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Adam J. Prus, Ph.D. - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
Behavioral Pharmacology of Antipsychotics Drugs, Leraning & Cognition
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Prus AJ, Van Fossen MT, Iannucci AN, Dalton AG, Prete JN. Discriminative stimulus properties of two training doses of gabapentin in rats: Substitution by pregabalin, diazepam, and pentobarbital. Experimental and Clinical Psychopharmacology. PMID 38236222 DOI: 10.1037/pha0000704  0.772
2023 Park-Oates M, Prus AJ. Lack of sex and estrous stage effects on compulsive behavior assessed using a schedule-induced polydipsia procedure in rats. Behavioural Pharmacology. PMID 36939582 DOI: 10.1097/FBP.0000000000000723  0.707
2021 Lynch CJ, Prus AJ. Assessment of antidepressant-like effects of dextromethorphan on differential reinforcement of low-rate 72-s performance in rats. Behavioural Pharmacology. PMID 34417357 DOI: 10.1097/FBP.0000000000000649  0.768
2018 Porter JH, Prus AJ, Overton DA. Drug Discrimination: Historical Origins, Important Concepts, and Principles. Current Topics in Behavioral Neurosciences. PMID 29637526 DOI: 10.1007/7854_2018_40  0.806
2017 Carey LM, Rice RJ, Prus AJ. The Neurotensin NTS1 Receptor Agonist PD149163 Produces Antidepressant-Like Effects in the Forced Swim Test: Further Support for Neurotensin as a Novel Pharmacologic Strategy for Antidepressant Drugs. Drug Development Research. PMID 28736839 DOI: 10.1002/Ddr.21393  0.758
2017 Porter JH, Webster KA, Prus AJ. Translational Value of Drug Discrimination with Typical and Atypical Antipsychotic Drugs. Current Topics in Behavioral Neurosciences. PMID 28341945 DOI: 10.1007/7854_2017_4  0.864
2017 Steele FF, Whitehouse SC, Aday JS, Prus AJ. Neurotensin NTS1 and NTS2 receptor agonists produce anxiolytic-like effects in the 22-kHz ultrasonic vocalization model in rats. Brain Research. PMID 28089664 DOI: 10.1016/J.Brainres.2017.01.012  0.751
2016 Prus AJ, Wise LE, Pehrson AL, Philibin SD, Bang-Andersen B, Arnt J, Porter JH. Discriminative stimulus properties of 1.25 mg/kg clozapine in rats: mediation by serotonin 5-HT2and dopamine D4 receptors. Brain Research. PMID 27502027 DOI: 10.1016/J.Brainres.2016.08.004  0.842
2016 Prus AJ, Porter JH. The Discriminative Stimulus Properties of Drugs Used to Treat Depression and Anxiety. Current Topics in Behavioral Neurosciences. PMID 27352389 DOI: 10.1007/7854_2016_27  0.811
2015 Prus AJ, Mooney-Leber SM, Berquist MD, Pehrson AL, Porter NP, Porter JH. The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats: enhancement of fluoxetine's effects by the α2 adrenoceptor antagonist yohimbine. Behavioural Pharmacology. 26: 489-94. PMID 26154437 DOI: 10.1097/Fbp.0000000000000159  0.813
2014 Hillhouse TM, Shankland Z, Matazel KS, Keiser AA, Prus AJ. The quetiapine active metabolite N-desalkylquetiapine and the neurotensin NTS₁ receptor agonist PD149163 exhibit antidepressant-like effects on operant responding in male rats. Experimental and Clinical Psychopharmacology. 22: 548-56. PMID 25285844 DOI: 10.1037/A0038156  0.835
2014 Keiser AA, Matazel KS, Esser MK, Feifel D, Prus AJ. Systemic administration of the neurotensin NTS₁-receptor agonist PD149163 improves performance on a memory task in naturally deficient male brown Norway rats. Experimental and Clinical Psychopharmacology. 22: 541-7. PMID 25222546 DOI: 10.1037/A0037912  0.755
2014 Prus AJ, Schuck CJ, Rusch KR, Carey LM. The discriminative stimulus effects of the neurotensin NTS1 receptor agonist PD149163 in rats: stimulus generalization testing with dopamine D1 and D2 receptor ligands. Drug Development Research. 75: 47-58. PMID 24668440 DOI: 10.1002/Ddr.21171  0.779
2014 Prus AJ, Hillhouse TM, LaCrosse AL. Acute, but not repeated, administration of the neurotensin NTS1 receptor agonist PD149163 decreases conditioned footshock-induced ultrasonic vocalizations in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 49: 78-84. PMID 24275076 DOI: 10.1016/J.Pnpbp.2013.11.011  0.807
2013 Hillhouse TM, Prus AJ. Effects of the neurotensin NTS₁ receptor agonist PD149163 on visual signal detection in rats. European Journal of Pharmacology. 721: 201-7. PMID 24076181 DOI: 10.1016/J.Ejphar.2013.09.035  0.833
2013 Berquist Ii MD, Mooney-Leber SM, Feifel D, Prus AJ. Assessment of attention in male and female Brattleboro rats using a self-paced five-choice serial reaction time task. Brain Research. 1537: 174-9. PMID 24055104 DOI: 10.1016/J.Brainres.2013.09.012  0.703
2011 Holly EN, Ebrecht B, Prus AJ. The neurotensin-1 receptor agonist PD149163 inhibits conditioned avoidance responding without producing catalepsy in rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 526-31. PMID 21277173 DOI: 10.1016/J.Euroneuro.2010.12.004  0.802
2010 Jacobson SM, Prus AJ. Evaluation of the effects of α2 adrenoceptor antagonism with the D2 receptor antagonist raclopride on conditioned avoidance responding in rats. Behavioural Pharmacology. 21: 654-9. PMID 20729715 DOI: 10.1097/Fbp.0B013E32833E7Efd  0.763
2010 Prus AJ, Zornio PA, Schuck CJ, Heerts T, Jacobson SM, Winiarski DA. Discriminative stimulus properties of idazoxan: Mediation by both α2 adrenoceptor antagonism and 5-HT1A receptor agonism Drug Development Research. 71: 261-267. DOI: 10.1002/Ddr.20370  0.788
2009 Li Z, Prus AJ, Dai J, Meltzer HY. Differential effects of M1 and 5-hydroxytryptamine1A receptors on atypical antipsychotic drug-induced dopamine efflux in the medial prefrontal cortex. The Journal of Pharmacology and Experimental Therapeutics. 330: 948-55. PMID 19491322 DOI: 10.1124/Jpet.109.155663  0.785
2009 Porter JH, Prus AJ. Drug discrimination: 30 years of progress. Psychopharmacology. 203: 189-91. PMID 19225764 DOI: 10.1007/S00213-009-1478-7  0.801
2009 Philibin SD, Walentiny DM, Vunck SA, Prus AJ, Meltzer HY, Porter JH. Further characterization of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in C57BL/6 mice: role of 5-HT(2A) serotonergic and alpha (1) adrenergic antagonism. Psychopharmacology. 203: 303-15. PMID 18989659 DOI: 10.1007/S00213-008-1385-3  0.812
2009 Porter JH, Prus AJ. Discriminative stimulus properties of atypical and typical antipsychotic drugs: a review of preclinical studies. Psychopharmacology. 203: 279-94. PMID 18795269 DOI: 10.1007/S00213-008-1308-3  0.852
2009 Prus AJ, Pehrson AL, Philibin SD, Wood JT, Vunck SA, Porter JH. The role of M1 muscarinic cholinergic receptors in the discriminative stimulus properties of N-desmethylclozapine and the atypical antipsychotic drug clozapine in rats. Psychopharmacology. 203: 295-301. PMID 18685832 DOI: 10.1007/S00213-008-1262-0  0.832
2008 Prus AJ, Vann RE, Rosecrans JA, James JR, Pehrson AL, O'Connell MM, Philibin SD, Robinson SE. Acute nicotine reduces and repeated nicotine increases spontaneous activity in male and female Lewis rats. Pharmacology, Biochemistry, and Behavior. 91: 150-4. PMID 18644403 DOI: 10.1016/J.Pbb.2008.06.024  0.774
2007 Prus AJ, Huang M, Li Z, Dai J, Meltzer HY. The neurotensin analog NT69L enhances medial prefrontal cortical dopamine and acetylcholine efflux: potentiation of risperidone-, but not haloperidol-, induced dopamine efflux. Brain Research. 1184: 354-64. PMID 17988654 DOI: 10.1016/J.Brainres.2007.09.092  0.764
2007 Li Z, Bonhaus DW, Huang M, Prus AJ, Dai J, Meltzer HY. AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus. European Journal of Pharmacology. 572: 129-37. PMID 17628522 DOI: 10.1016/J.Ejphar.2007.06.025  0.766
2007 Li Z, Huang M, Prus AJ, Dai J, Meltzer HY. 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. Brain Research. 1134: 70-8. PMID 17207474 DOI: 10.1016/J.Brainres.2006.11.060  0.798
2007 Prus AJ, Maxwell AT, Baker KM, Rosecrans JA, James JR. Acute behavioral tolerance to nicotine in the conditioned taste aversion paradigm Drug Development Research. 68: 522-528. DOI: 10.1002/Ddr.20219  0.731
2006 Prus AJ, Philibin SD, Pehrson AL, Porter JH. Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle. Behavioural Pharmacology. 17: 185-94. PMID 16495726 DOI: 10.1097/01.Fbp.0000197457.70774.91  0.858
2006 Meltzer H, Prus A. NK3 receptor antagonists for the treatment of schizophrenia Drug Discovery Today: Therapeutic Strategies. 3: 555-560. DOI: 10.1016/J.Ddstr.2006.11.013  0.745
2006 Meltzer HY, Li Z, Huang M, Prus A. Serotonergic mechanisms in schizophrenia: Evolution and current concepts Current Psychosis and Therapeutics Reports. 4: 12-19. DOI: 10.1007/Bf02629409  0.751
2005 Li Z, Ichikawa J, Huang M, Prus AJ, Dai J, Meltzer HY. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology. 183: 144-53. PMID 16220333 DOI: 10.1007/S00213-005-0170-9  0.759
2005 Prus AJ, Philibin SD, Pehrson AL, Porter JH. Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine versus vehicle in a three-choice drug discrimination task. Behavioural Pharmacology. 16: 511-20. PMID 16170228 DOI: 10.1097/01.fbp.0000172735.73876.06  0.827
2005 Philibin SD, Prus AJ, Pehrson AL, Porter JH. Serotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL/6 mice. Psychopharmacology. 180: 49-56. PMID 15696329 DOI: 10.1007/S00213-005-2147-0  0.849
2005 Porter JH, Prus AJ, Vann RE, Varvel SA. Discriminative stimulus properties of the atypical antipsychotic clozapine and the typical antipsychotic chlorpromazine in a three-choice drug discrimination procedure in rats. Psychopharmacology. 178: 67-77. PMID 15316715 DOI: 10.1007/S00213-004-1985-5  0.862
2005 Prus A, Philibin S, Pehrson A, Wood E, Porter J. A82 THE DISCRIMINATIVE STIMULUS PROPERTIES OF THE ATYPICAL ANTIPSYCHOTIC DRUG CLOZAPINE IN RATS TRAINED TO DISCRIMINATE 1.25???mg/kg CLOZAPINE VERSUS 5.0???mg/kg CLOZAPINE VERSUS VEHICLE IN A THREE-CHOICE DRUG DISCRIMINATION TASK Behavioural Pharmacology. 16: S49. DOI: 10.1097/00008877-200509001-00155  0.84
2005 Porter J, Cooper R, Prus A, Stephens C, Pehrson A, Wood E, Porter N, Glowa J. A64 THE ??2 ANTAGONIST YOHIMBINE ACCELERATES THE EFFECTS OF THE SSRI FLUOXETINE ON SCHEDULE-INDUCED POLYDIPSIA Behavioural Pharmacology. 16: S43. DOI: 10.1097/00008877-200509001-00136  0.781
2005 Prus AJ, Philibin SD, Pehrson AL, Stephens CL, Cooper RN, Wise LE, Porter JH. Generalization testing with atypical and typical antipsychotic drugs in rats trained to discriminate 5.0 mg/kg clozapine from vehicle in a two-choice drug discrimination task Drug Development Research. 64: 55-65. DOI: 10.1002/Ddr.10419  0.824
2004 Prus AJ, Baker LE, Meltzer HY. Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms. Pharmacology, Biochemistry, and Behavior. 77: 199-208. PMID 14751446 DOI: 10.1016/J.Pbb.2003.10.010  0.825
2002 Baker LE, Prus AJ. Reevaluation of PNU-99194A discriminative stimulus effects: potentiation by both a D2 antagonist and a D3/D2 agonist. Pharmacology, Biochemistry, and Behavior. 73: 753-8. PMID 12213519 DOI: 10.1016/S0091-3057(02)00882-1  0.75
2001 Goudie AJ, Baker LE, Smith JA, Prus AJ, Svensson KA, Cortes-Burgos LA, Wong EH, Haadsma-Svensson S. Common discriminative stimulus properties in rats of muscarinic antagonists, clozapine and the D3 preferring antagonist PNU-99194a: an analysis of possible mechanisms. Behavioural Pharmacology. 12: 303-15. PMID 11710745 DOI: 10.1097/00008877-200109000-00001  0.748
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