| Year |
Citation |
Score |
| 2023 |
Akiyama T, Raftery LA, Wharton KA. Bone morphogenetic protein signaling: the pathway and its regulation. Genetics. PMID 38124338 DOI: 10.1093/genetics/iyad200 |
0.796 |
|
| 2023 |
Groppe JC, Lu G, Tandang-Silvas MR, Pathi A, Konda S, Wu J, Le VQ, Culbert AL, Shore EM, Wharton KA, Kaplan FS. Polypeptide Substrate Accessibility Hypothesis: Gain-of-Function R206H Mutation Allosterically Affects Activin Receptor-like Protein Kinase Activity. Biomolecules. 13. PMID 37509165 DOI: 10.3390/biom13071129 |
0.732 |
|
| 2023 |
Bauer M, Aguilar G, Wharton KA, Matsuda S, Affolter M. Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila. Developmental Cell. PMID 37054707 DOI: 10.1016/j.devcel.2023.03.008 |
0.663 |
|
| 2021 |
Johnston AM, Chang LW, Wharton K, Santos LR. Dogs (Canis familiaris) prioritize independent exploration over looking back. Journal of Comparative Psychology (Washington, D.C. : 1983). 135: 370-381. PMID 34553976 DOI: 10.1037/com0000233 |
0.552 |
|
| 2021 |
Russo K, Wharton KA. BMP/TGF-β signaling as a modulator of neurodegeneration in ALS. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 33745185 DOI: 10.1002/dvdy.333 |
0.784 |
|
| 2019 |
Bartoletti M, Bosco DA, Da Cruz S, Lagier-Tourenne C, Liachko N, Markmiller S, Webster KM, Wharton KA. Phenotypic Suppression of ALS/FTD-Associated Neurodegeneration Highlights Mechanisms of Dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 39: 8217-8224. PMID 31619490 DOI: 10.1523/Jneurosci.1159-19.2019 |
0.776 |
|
| 2019 |
Held A, Major P, Sahin A, Reenan R, Lipscombe D, Wharton KA. Circuit dysfunction in model first detected in sensory feedback prior to motor neuron degeneration is alleviated by BMP signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30659087 DOI: 10.1523/Jneurosci.1771-18.2019 |
0.767 |
|
| 2019 |
Yanagi KS, Wu Z, Amaya J, Chapkis N, Duffy AM, Hajdarovic KH, Held A, Mathur AD, Russo K, Ryan VH, Steinert BL, Whitt JP, Fallon JR, Fawzi NL, Lipscombe D, ... Wharton KA, et al. Meta-analysis of Genetic Modifiers Reveals Candidate Dysregulated Pathways in Amyotrophic Lateral Sclerosis. Neuroscience. 396: A3-A20. PMID 30594291 DOI: 10.1016/J.Neuroscience.2018.10.033 |
0.764 |
|
| 2018 |
Borensztejn A, Mascaro A, Wharton KA. Corrigendum to "JAK/STAT signaling prevents excessive apoptosis to ensure maintenance of the interfollicular stalk critical for Drosophila oogenesis" [Dev. Biol. 438 (2018) 1-9]. Developmental Biology. PMID 30309615 DOI: 10.1016/J.Ydbio.2018.09.020 |
0.763 |
|
| 2018 |
Borensztejn A, Mascaro A, Wharton KA. JAK/STAT signaling prevents excessive apoptosis to ensure maintenance of the interfollicular stalk critical for Drosophila oogenesis. Developmental Biology. PMID 29571611 DOI: 10.1016/J.Ydbio.2018.03.018 |
0.764 |
|
| 2018 |
Kanai MI, Kim MJ, Akiyama T, Takemura M, Wharton K, O'Connor MB, Nakato H. Regulation of neuroblast proliferation by surface glia in the Drosophila larval brain. Scientific Reports. 8: 3730. PMID 29487331 DOI: 10.1038/S41598-018-22028-Y |
0.763 |
|
| 2017 |
Le V, Anderson E, Akiyama T, Wharton KA. Drosophila models of FOP provide mechanistic insight. Bone. PMID 29128351 DOI: 10.1016/J.Bone.2017.11.001 |
0.82 |
|
| 2017 |
Anderson EN, Wharton KA. Alternative cleavage of the bone morphogenetic protein (BMP), Gbb, produces ligands with distinct developmental functions and receptor preference. The Journal of Biological Chemistry. PMID 28924042 DOI: 10.1074/Jbc.M117.793513 |
0.752 |
|
| 2016 |
Şahin A, Held A, Bredvik K, Major P, Achilli TM, Kerson AG, Wharton K, Stilwell G, Reenan R. Human SOD1 ALS Mutations in a Drosophila Knock-In Model Cause Severe Phenotypes and Reveal Dosage-Sensitive Gain and Loss of Function Components. Genetics. PMID 27974499 DOI: 10.1534/Genetics.116.190850 |
0.786 |
|
| 2015 |
Wharton K. William Martin Gelbart 1945-2015. Nature Genetics. 47: 1372. PMID 26620108 DOI: 10.1038/Ng.3455 |
0.615 |
|
| 2015 |
McGinniss MJ, Eberhard DA, Wharton KA. Next-generation sequencing (Ngs) in anatomic pathology discovery and practice Methods in Pharmacology and Toxicology. 20: 219-257. DOI: 10.1007/7653_2014_39 |
0.569 |
|
| 2015 |
Wharton KA. Histopathology: A canvas and landscape of disease in drug and diagnostic development Methods in Pharmacology and Toxicology. 20: 1-26. DOI: 10.1007/7653_2014_33 |
0.553 |
|
| 2015 |
Wharton KA, Lee BH, Moulin P, Mongeon D, Hillenbrand R, Gusev A, Ye B, Jiang X. Outsourcing tissue histopathology investigations in support of clinical trials for novel therapeutics: Considerations and perspectives Methods in Pharmacology and Toxicology. 20: 43-63. DOI: 10.1007/7653_2014_28 |
0.548 |
|
| 2014 |
James RE, Hoover KM, Bulgari D, McLaughlin CN, Wilson CG, Wharton KA, Levitan ES, Broihier HT. Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction. Developmental Cell. 31: 586-98. PMID 25453556 DOI: 10.1016/J.Devcel.2014.10.006 |
0.641 |
|
| 2013 |
Wharton KA, Serpe M. Fine-tuned shuttles for bone morphogenetic proteins. Current Opinion in Genetics & Development. 23: 374-84. PMID 23735641 DOI: 10.1016/J.Gde.2013.04.012 |
0.655 |
|
| 2012 |
Boulanger A, Farge M, Ramanoudjame C, Wharton K, Dura JM. Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-β/BMP signaling and orphan nuclear receptors. Plos One. 7: e40255. PMID 22792255 DOI: 10.1371/Journal.Pone.0040255 |
0.642 |
|
| 2012 |
Akiyama T, Marqués G, Wharton KA. A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing. Science Signaling. 5: ra28. PMID 22472650 DOI: 10.1126/Scisignal.2002549 |
0.642 |
|
| 2012 |
Le VQ, Wharton KA. Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 200-14. PMID 22174087 DOI: 10.1002/Dvdy.22779 |
0.759 |
|
| 2011 |
Dunstan RW, Wharton KA, Quigley C, Lowe A. The use of immunohistochemistry for biomarker assessment--can it compete with other technologies? Toxicologic Pathology. 39: 988-1002. PMID 21971934 DOI: 10.1177/0192623311419163 |
0.569 |
|
| 2010 |
Ballard SL, Jarolimova J, Wharton KA. Gbb/BMP signaling is required to maintain energy homeostasis in Drosophila. Developmental Biology. 337: 375-85. PMID 19914231 DOI: 10.1016/J.Ydbio.2009.11.011 |
0.68 |
|
| 2010 |
Aldrich M, Soares L, Wharton K. Investigating the regulatory sequences of dpp required for negative feedback of dpp transcription Developmental Biology. 344: 489. DOI: 10.1016/J.Ydbio.2010.05.424 |
0.736 |
|
| 2010 |
Le VQ, Wharton K. A Drosophila model for fibrodysplasia ossificans progressiva (FOP) Developmental Biology. 344: 508. DOI: 10.1016/J.Ydbio.2010.05.342 |
0.706 |
|
| 2009 |
Chung S, Vining MS, Bradley PL, Chan CC, Wharton KA, Andrew DJ. Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length. Plos Genetics. 5: e1000746. PMID 19956736 DOI: 10.1371/Journal.Pgen.1000746 |
0.64 |
|
| 2009 |
Guo J, Cagatay T, Zhou G, Chan CC, Blythe S, Suyama K, Zheng L, Pan K, Qian C, Hamelin R, Thibodeau SN, Klein PS, Wharton KA, Liu W. Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling. Plos One. 4: e7982. PMID 19956716 DOI: 10.1371/Journal.Pone.0007982 |
0.668 |
|
| 2009 |
Wharton K, Derynck R. TGFbeta family signaling: novel insights in development and disease. Development (Cambridge, England). 136: 3691-7. PMID 19855012 DOI: 10.1242/Dev.040584 |
0.701 |
|
| 2009 |
Twombly V, Bangi E, Le V, Malnic B, Singer MA, Wharton KA. Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2. Genetics. 183: 563-79, 1SI-8SI. PMID 19620392 DOI: 10.1534/Genetics.109.105585 |
0.775 |
|
| 2008 |
Prabhat, Forsberg A, Katzourin M, Wharton K, Slater M. A comparative study of Desktop, Fishtank, and Cave systems for the exploration of volume rendered confocal data sets. Ieee Transactions On Visualization and Computer Graphics. 14: 551-63. PMID 18461742 DOI: 10.1109/Tvcg.2007.70433 |
0.583 |
|
| 2008 |
Chan CC, Zhang S, Rousset R, Wharton KA. Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-alpha3 to antagonize Wnt/beta-catenin signaling. Developmental Biology. 318: 17-28. PMID 18423435 DOI: 10.1016/J.Ydbio.2008.02.050 |
0.673 |
|
| 2008 |
DeCarolis NA, Wharton KA, Eisch AJ. Which way does the Wnt blow? Exploring the duality of canonical Wnt signaling on cellular aging. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 30: 102-6. PMID 18200563 DOI: 10.1002/bies.20709 |
0.658 |
|
| 2007 |
Chan CC, Zhang S, Cagatay T, Wharton KA. Cell-autonomous, myristyl-independent activity of the Drosophila Wnt/Wingless antagonist Naked cuticle (Nkd). Developmental Biology. 311: 538-53. PMID 17942091 DOI: 10.1016/J.Ydbio.2007.09.002 |
0.696 |
|
| 2007 |
Sokol SY, Wharton KA. WNTers in La Jolla. Development (Cambridge, England). 134: 3393-9. PMID 17827178 DOI: 10.1242/dev.008169 |
0.673 |
|
| 2007 |
Zhang S, Cagatay T, Amanai M, Zhang M, Kline J, Castrillon DH, Ashfaq R, Oz OK, Wharton KA. Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. Molecular and Cellular Biology. 27: 4454-64. PMID 17438140 DOI: 10.1128/MCB.00133-07 |
0.679 |
|
| 2006 |
Zhang L, Jia J, Wang B, Amanai K, Wharton KA, Jiang J. Regulation of wingless signaling by the CKI family in Drosophila limb development. Developmental Biology. 299: 221-37. PMID 16987508 DOI: 10.1016/j.ydbio.2006.07.025 |
0.683 |
|
| 2006 |
Bangi E, Wharton K. Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc. Development (Cambridge, England). 133: 3295-303. PMID 16887821 DOI: 10.1242/Dev.02513 |
0.815 |
|
| 2006 |
Waldrop S, Chan CC, Cagatay T, Zhang S, Rousset R, Mack J, Zeng W, Fish M, Zhang M, Amanai M, Wharton KA. An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle. Genetics. 174: 331-48. PMID 16849595 DOI: 10.1534/genetics.106.061853 |
0.699 |
|
| 2006 |
Karner C, Wharton KA, Carroll TJ. Planar cell polarity and vertebrate organogenesis. Seminars in Cell & Developmental Biology. 17: 194-203. PMID 16839790 DOI: 10.1016/j.semcdb.2006.05.003 |
0.609 |
|
| 2006 |
Karner C, Wharton KA, Carroll TJ. Apical-basal polarity, Wnt signaling and vertebrate organogenesis. Seminars in Cell & Developmental Biology. 17: 214-22. PMID 16839789 DOI: 10.1016/j.semcdb.2006.05.007 |
0.659 |
|
| 2006 |
Bangi E, Wharton K. Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning. Developmental Biology. 295: 178-93. PMID 16643887 DOI: 10.1016/J.Ydbio.2006.03.021 |
0.797 |
|
| 2005 |
Koch A, Waha A, Hartmann W, Hrychyk A, Schüller U, Waha A, Wharton KA, Fuchs SY, von Schweinitz D, Pietsch T. Elevated expression of Wnt antagonists is a common event in hepatoblastomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4295-304. PMID 15958610 DOI: 10.1158/1078-0432.CCR-04-1162 |
0.635 |
|
| 2004 |
Sinenko SA, Kim EK, Wynn R, Manfruelli P, Ando I, Wharton KA, Perrimon N, Mathey-Prevot B. Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology. 273: 48-62. PMID 15302597 DOI: 10.1016/J.Ydbio.2004.05.022 |
0.648 |
|
| 2003 |
Wharton KA. Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Developmental Biology. 253: 1-17. PMID 12490194 DOI: 10.1006/dbio.2002.0869 |
0.688 |
|
| 2002 |
Rousset R, Wharton KA, Zimmermann G, Scott MP. Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle. The Journal of Biological Chemistry. 277: 49019-26. PMID 12354775 DOI: 10.1074/jbc.M203246200 |
0.634 |
|
| 2001 |
Ray RP, Wharton KA. Context-dependent relationships between the BMPs gbb and dpp during development of the Drosophila wing imaginal disk. Development (Cambridge, England). 128: 3913-25. PMID 11641216 |
0.754 |
|
| 2001 |
Wharton KA, Zimmermann G, Rousset R, Scott MP. Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling. Developmental Biology. 234: 93-106. PMID 11356022 DOI: 10.1006/dbio.2001.0238 |
0.697 |
|
| 2001 |
Ray RP, Wharton KA. Twisted perspective: new insights into extracellular modulation of BMP signaling during development. Cell. 104: 801-4. PMID 11290316 DOI: 10.1016/S0092-8674(01)00275-6 |
0.723 |
|
| 2001 |
Rousset R, Mack JA, Wharton KA, Axelrod JD, Cadigan KM, Fish MP, Nusse R, Scott MP. Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes & Development. 15: 658-71. PMID 11274052 DOI: 10.1101/Gad.869201 |
0.705 |
|
| 2000 |
Zeng W, Wharton KA, Mack JA, Wang K, Gadbaw M, Suyama K, Klein PS, Scott MP. naked cuticle encodes an inducible antagonist of Wnt signalling. Nature. 403: 789-95. PMID 10693810 DOI: 10.1038/35001615 |
0.695 |
|
| 1999 |
Wharton KA, Cook JM, Torres-Schumann S, de Castro K, Borod E, Phillips DA. Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development. Genetics. 152: 629-40. PMID 10353905 |
0.69 |
|
| 1998 |
Haerry TE, Khalsa O, O'Connor MB, Wharton KA. Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila. Development (Cambridge, England). 125: 3977-87. PMID 9735359 |
0.657 |
|
| 1998 |
Khalsa O, Yoon JW, Torres-Schumann S, Wharton KA. TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing. Development (Cambridge, England). 125: 2723-34. PMID 9636086 |
0.656 |
|
| 1997 |
Johnson LA, Longacre TA, Wharton KA, Jeffrey RB. Multiple mesenteric lymphatic cysts: an unusual feature of mesenteric panniculitis (sclerosing mesenteritis). Journal of Computer Assisted Tomography. 21: 103-5. PMID 9022778 DOI: 10.1097/00004728-199701000-00019 |
0.539 |
|
| 1996 |
Wharton K, Ray RP, Findley SD, Duncan HE, Gelbart WM. Molecular lesions associated with alleles of decapentaplegic identify residues necessary for TGF-beta/BMP cell signaling in Drosophila melanogaster. Genetics. 142: 493-505. PMID 8852848 |
0.768 |
|
| 1995 |
Raftery LA, Twombly V, Wharton K, Gelbart WM. Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics. 139: 241-54. PMID 7705627 |
0.804 |
|
| 1995 |
Wharton KA. How many receptors does it take? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 17: 13-6. PMID 7702589 DOI: 10.1002/Bies.950170105 |
0.663 |
|
| 1994 |
Wharton KA, Franks RG, Kasai Y, Crews ST. Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation. Development (Cambridge, England). 120: 3563-9. PMID 7821222 |
0.642 |
|
| 1993 |
Wharton KA, Crews ST. CNS midline enhancers of the Drosophila slit and Toll genes. Mechanisms of Development. 40: 141-54. PMID 8494768 DOI: 10.1016/0925-4773(93)90072-6 |
0.622 |
|
| 1993 |
Wharton KA, Ray RP, Gelbart WM. An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development (Cambridge, England). 117: 807-22. PMID 8330541 |
0.763 |
|
| 1992 |
Zipfel PF, Wharton KA, Villalobos J, Irving SG, Kelly K, Siebenlist U. Employment of antipeptide antisera to distinguish two closely related cytokines induced in human T cells. Lymphokine and Cytokine Research. 11: 141-8. PMID 1391233 |
0.591 |
|
| 1991 |
Wharton KA, Thomsen GH, Gelbart WM. Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins. Proceedings of the National Academy of Sciences of the United States of America. 88: 9214-8. PMID 1924384 DOI: 10.1073/Pnas.88.20.9214 |
0.695 |
|
| 1991 |
Watts IS, Wharton KA, White BP, Lumley P. Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets. British Journal of Pharmacology. 102: 497-505. PMID 1826620 |
0.563 |
|
| 1991 |
Lumley P, Keery RJ, Wharton KA, White BP, Watts IS. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 21: 603-6. PMID 1825385 |
0.562 |
|
| 1991 |
Nambu JR, Lewis JO, Wharton KA, Crews ST. The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell. 67: 1157-67. PMID 1760843 DOI: 10.1016/0092-8674(91)90292-7 |
0.662 |
|
| 1989 |
Watts IS, White BP, Wharton KA, Lumley P. Comparison of GR32191, R68070 and CV-4151 upon U-46619- and collagen-induced platelet aggregation in vitro and ex vivo. British Journal of Pharmacology. 98: 842P. PMID 2611538 |
0.543 |
|
| 1989 |
Ramos RG, Grimwade BG, Wharton KA, Scottgale TN, Artavanis-Tsakonas S. Physical and functional definition of the Drosophila Notch locus by P element transformation. Genetics. 123: 337-48. PMID 2555253 |
0.789 |
|
| 1985 |
Wharton KA, Johansen KM, Xu T, Artavanis-Tsakonas S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell. 43: 567-81. PMID 3935325 DOI: 10.1016/0092-8674(85)90229-6 |
0.758 |
|
| 1985 |
Wharton KA, Yedvobnick B, Finnerty VG, Artavanis-Tsakonas S. opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Cell. 40: 55-62. PMID 2981631 DOI: 10.1016/0092-8674(85)90308-3 |
0.716 |
|
| 1985 |
Yedvobnick B, Muskavitch MA, Wharton KA, Halpern ME, Paul E, Grimwade BG, Artavanis-Tsakonas S. Molecular genetics of Drosophila neurogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 50: 841-54. PMID 2420520 |
0.754 |
|
| 1982 |
Mooseker MS, Bonder EM, Grimwade BG, Howe CL, Keller TC, Wasserman RH, Wharton KA. Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells. Cold Spring Harbor Symposia On Quantitative Biology. 46: 855-70. PMID 6955109 DOI: 10.1101/Sqb.1982.046.01.080 |
0.764 |
|
| 1982 |
Mooseker MS, Pollard TD, Wharton KA. Nucleated polymerization of actin from the membrane-associated ends of microvillar filaments in the intestinal brush border. The Journal of Cell Biology. 95: 223-33. PMID 6890554 DOI: 10.1083/Jcb.95.1.223 |
0.564 |
|
| 1980 |
Mooseker MS, Graves TA, Wharton KA, Falco N, Howe CL. Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells. The Journal of Cell Biology. 87: 809-22. PMID 6893989 DOI: 10.1083/Jcb.87.3.809 |
0.559 |
|
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