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Jonathan A. Kirk, Ph.D. - Publications

Affiliations: 
2009 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Biomedical Engineering
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang J, Tomar D, Martin TG, Dubey S, Dubey PK, Song J, Landesberg G, McCormick MG, Myers VD, Merali S, Merali C, Lemster B, McTiernan CF, Khalili K, Madesh M, ... ... Kirk JA, et al. Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart. Jacc. Basic to Translational Science. 8: 820-839. PMID 37547075 DOI: 10.1016/j.jacbts.2022.12.013  0.301
2022 Eaton DM, Martin TG, Kasa M, Djalinac N, Ljubojevic-Holzer S, Von Lewinski D, Pöttler M, Kampaengsri T, Krumphuber A, Scharer K, Maechler H, Zirlik A, McKinsey TA, Kirk JA, Houser SR, et al. HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension. Pharmaceutics. 14. PMID 35890404 DOI: 10.3390/pharmaceutics14071509  0.32
2020 DiNello E, Bovo E, Thuo P, Martin TG, Kirk JA, Zima AV, Cao Q, Kuo IY. Deletion of cardiac polycystin 2/PC2 results in increased SR calcium release and blunted adrenergic reserve. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32946258 DOI: 10.1152/Ajpheart.00302.2020  0.386
2020 Martin TG, Kirk JA. Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere. Journal of Molecular and Cellular Cardiology. PMID 32920010 DOI: 10.1016/J.Yjmcc.2020.08.018  0.361
2020 Ai L, Perez E, Asimes A, Kampaengsri T, Heroux M, Zlobin A, Hiske MA, Chung CS, Pak TR, Kirk JA. Binge Alcohol Exposure in Adolescence Impairs Normal Heart Growth. Journal of the American Heart Association. e015611. PMID 32319345 DOI: 10.1161/Jaha.119.015611  0.307
2020 Pitoulis FG, Hasan W, Papadaki M, Clavere NG, Perbellini F, Harding SE, Kirk JA, Boateng SY, de Tombe PP, Terracciano CM. Intact myocardial preparations reveal intrinsic transmural heterogeneity in cardiac mechanics. Journal of Molecular and Cellular Cardiology. PMID 32201175 DOI: 10.1016/J.Yjmcc.2020.03.007  0.427
2020 Seflova J, Pribadi M, Kirk J, Heroux A, Zima AV, Robia SL. Insight into Sodium Pump Regulation in the Failing Human Heart Biophysical Journal. 118: 129a. DOI: 10.1016/J.Bpj.2019.11.838  0.363
2020 Stachowski MJ, Zlobin A, Papadaki M, Perez E, Martin JL, Aima Muntu N, Moravec CS, Kirk JA. An Independent Pool of GSK-3β Modulates Calcium Sensitivity at the Cardiac Myofilament Biophysical Journal. 118: 592a-593a. DOI: 10.1016/J.Bpj.2019.11.3208  0.331
2019 Martin TG, Myers V, Willis M, Feldman A, Kirk JA. Abstract 909: Determining the Role of the Co-chaperone BAG3 at the Cardiac Myofilament Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.909  0.367
2018 Rattanasopa C, Kirk JA, Bupha-Intr T, Papadaki M, de Tombe PP, Wattanapermpool J. Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30499711 DOI: 10.1152/Ajpheart.00428.2018  0.33
2018 Papadaki M, Holewinski RJ, Previs SB, Martin TG, Stachowski MJ, Li A, Blair CA, Moravec CS, Van Eyk JE, Campbell KS, Warshaw DM, Kirk JA. Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function. Jci Insight. 3. PMID 30333300 DOI: 10.1016/J.Bpj.2018.11.645  0.364
2018 Stachowski MJ, Holewinski RJ, Grote E, Venkatraman V, Van Eyk JE, Kirk JA. Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy. Proteomics. 18: e1800079. PMID 30129105 DOI: 10.1002/Pmic.201800079  0.42
2018 Kirk JA, Frangogiannis NG. Galectin-3 in the pathogenesis of heart failure: a causative mediator or simply a biomarker? American Journal of Physiology. Heart and Circulatory Physiology. PMID 29498533 DOI: 10.1152/Ajpheart.00150.2018  0.361
2018 Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA. Right Ventricular Myofilament Functional Differences in Humans with Systemic Sclerosis-associated versus Idiopathic Pulmonary Arterial Hypertension. Circulation. PMID 29352073 DOI: 10.1161/Circulationaha.117.033147  0.348
2018 Ranek MJ, Stachowski MJ, Kirk JA, Willis MS. The role of heat shock proteins and co-chaperones in heart failure. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29203715 DOI: 10.1098/Rstb.2016.0530  0.375
2017 Sonaglioni A, Baravelli M, Lombardo M, Sommese C, Anzà C, Kirk JA, Padeletti L. Ventricular-arterial coupling in centenarians without cardiovascular diseases. Aging Clinical and Experimental Research. PMID 28616854 DOI: 10.1007/S40520-017-0783-Y  0.31
2017 Kirk JA, Kass DA. Cellular and Molecular Aspects of Dyssynchrony and Resynchronization. Heart Failure Clinics. 13: 29-41. PMID 27886930 DOI: 10.1016/J.Hfc.2016.07.003  0.394
2017 Papadaki M, Holewinski R, Stachowski M, Kirk J. The Role of Methylglyoxal on the Cardiac Myofilament Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2614  0.376
2016 Ngkelo A, Richart A, Kirk JA, Bonnin P, Vilar J, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G, et al. Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction. The Journal of Experimental Medicine. 213: 1353-74. PMID 27353089 DOI: 10.1084/Jem.20160081  0.444
2016 Kirk JA, Cingolani OH. Thrombospondins in the transition from myocardial infarction to heart failure. Journal of Molecular and Cellular Cardiology. 90: 102-10. PMID 26686988 DOI: 10.1016/J.Yjmcc.2015.12.009  0.412
2016 Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE. Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials. Proteomics. 16: 894-905. PMID 26670943 DOI: 10.1002/Pmic.201500401  0.336
2016 Kirk JA, Holewinski RJ, Crowgey EL, Van Eyk JE. Front cover: Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials Proteomics. 16: NA-NA. DOI: 10.1002/Pmic.201670050  0.318
2015 Kirk JA, Chakir K, Lee KH, Karst E, Holewinski RJ, Pironti G, Tunin RS, Pozios I, Abraham TP, de Tombe P, Rockman HA, Van Eyk JE, Craig R, Farazi TG, Kass DA. Pacemaker-induced transient asynchrony suppresses heart failure progression. Science Translational Medicine. 7: 319ra207. PMID 26702095 DOI: 10.1126/Scitranslmed.Aad2899  0.431
2015 Kirk JA, Kass DA. Cellular and Molecular Aspects of Dyssynchrony and Resynchronization. Cardiac Electrophysiology Clinics. 7: 585-97. PMID 26596804 DOI: 10.1016/J.Ccep.2015.08.011  0.441
2015 Fert-Bober J, Giles JT, Holewinski RJ, Kirk JA, Uhrigshardt H, Crowgey EL, Andrade F, Bingham CO, Park JK, Halushka MK, Kass DA, Bathon JM, Van Eyk JE. Citrullination of myofilament proteins in heart failure. Cardiovascular Research. 108: 232-42. PMID 26113265 DOI: 10.1093/Cvr/Cvv185  0.397
2015 Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, et al. Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature. 519: 472-6. PMID 25799991 DOI: 10.1038/Nature14332  0.361
2015 Kirk JA, Holewinski RJ, Venkatraman V, Grote E, Kass DA, Van Eyk JE. Mass Spectrometry-Based Analysis of the Phospho-Proteome for Cardiac Dyssynchrony and Resynchronization Therapy Biophysical Journal. 108: 273a. DOI: 10.1016/J.Bpj.2014.11.1497  0.394
2014 Kirk JA, Paolocci N. New redox-related arrows in the arsenal of cardiac disease treatment. Antioxidants & Redox Signaling. 21: 1945-8. PMID 25211226 DOI: 10.1089/Ars.2014.6124  0.411
2014 Kooij V, Venkatraman V, Kirk JA, Ubaida-Mohien C, Graham DR, Faber MJ, Van Eyk JE. Identification of cardiac myofilament protein isoforms using multiple mass spectrometry based approaches. Proteomics. Clinical Applications. 8: 578-589. PMID 24974818 DOI: 10.1002/Prca.201400039  0.323
2014 Kooij V, Venkatraman V, Tra J, Kirk JA, Rowell J, Blice-Baum A, Cammarato A, Van Eyk JE. Sizing up models of heart failure: Proteomics from flies to humans. Proteomics. Clinical Applications. 8: 653-64. PMID 24723306 DOI: 10.1002/Prca.201300123  0.411
2014 Agnetti G, Halperin VL, Kirk JA, Chakir K, Guo Y, Lund L, Nicolini F, Gherli T, Guarnieri C, Caldarera CM, Tomaselli GF, Kass DA, Van Eyk JE. Desmin modifications associate with amyloid-like oligomers deposition in heart failure. Cardiovascular Research. 102: 24-34. PMID 24413773 DOI: 10.1093/Cvr/Cvu003  0.341
2014 Kirk JA, Holewinski RJ, Kooij V, Agnetti G, Tunin RS, Witayavanitkul N, de Tombe PP, Gao WD, Van Eyk J, Kass DA. Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β. The Journal of Clinical Investigation. 124: 129-38. PMID 24292707 DOI: 10.1172/Jci69253  0.397
2013 Kirk JA, Saccomani MP, Shroff SG. A Priori Identifiability Analysis of Cardiovascular Models. Cardiovascular Engineering and Technology. 4: 500-512. PMID 26726299 DOI: 10.1007/S13239-013-0157-3  0.543
2013 Kirk JA, Kass DA. Electromechanical dyssynchrony and resynchronization of the failing heart. Circulation Research. 113: 765-76. PMID 23989718 DOI: 10.1161/Circresaha.113.300270  0.443
2013 Kirk JA, Zhang P, Murphy AM, Van Eyk JE. Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure? Expert Review of Proteomics. 10: 5-8. PMID 23414352 DOI: 10.1586/Epr.12.77  0.335
2013 Kirk JA, Saccomani MP, Shroff SG. A Priori Identifiability Analysis of Cardiovascular Models Cardiovascular Engineering and Technology. 4: 500-512. DOI: 10.1007/s13239-013-0157-3  0.5
2012 Zhang P, Kirk JA, Ji W, dos Remedios CG, Kass DA, Van Eyk JE, Murphy AM. Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart. Circulation. 126: 1828-37. PMID 22972900 DOI: 10.1161/Circulationaha.112.096388  0.33
2012 Rainer PP, Doleschal B, Kirk JA, Sivakumaran V, Saad Z, Groschner K, Maechler H, Hoefler G, Bauernhofer T, Samonigg H, Hutterer G, Kass DA, Pieske B, von Lewinski D, Pichler M. Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes. Bju International. 110: 1455-62. PMID 22508007 DOI: 10.1111/J.1464-410X.2012.11134.X  0.323
2012 Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi S, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG. Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. The Journal of Clinical Investigation. 122: 291-302. PMID 22201686 DOI: 10.1172/Jci57426  0.394
2011 Cingolani OH, Kirk JA, Seo K, Koitabashi N, Lee DI, Ramirez-Correa G, Bedja D, Barth AS, Moens AL, Kass DA. Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle. Circulation Research. 109: 1410-4. PMID 22034490 DOI: 10.1161/Circresaha.111.256743  0.437
2011 Kirk JA, Kass DA, Cingolani OH. Thrombospondin-4 is Necessary for the Increased Calcium Cycling Associated with the Slow Force Response Biophysical Journal. 100: 344a. DOI: 10.1016/J.Bpj.2010.12.2079  0.376
2010 Clause KC, Tinney JP, Liu LJ, Gharaibeh B, Huard J, Kirk JA, Shroff SG, Fujimoto KL, Wagner WR, Ralphe JC, Keller BB, Tobita K. A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle-derived stem cells. Tissue Engineering. Part C, Methods. 16: 375-85. PMID 19601695 DOI: 10.1089/Ten.Tec.2009.0098  0.58
2009 Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG. Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I. Circulation Research. 105: 1232-9. PMID 19850940 DOI: 10.1161/Circresaha.109.205427  0.618
2009 Naghshin J, McGaffin KR, Witham WG, Mathier MA, Romano LC, Smith SH, Janczewski AM, Kirk JA, Shroff SG, O'Donnell CP. Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 787-93. PMID 19589954 DOI: 10.1152/Japplphysiol.91256.2008  0.598
2006 MacGowan GA, Kirk JA, Evans C, Shroff SG. Pressure-calcium relationships in perfused mouse hearts. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2614-24. PMID 16415077 DOI: 10.1152/Ajpheart.00979.2005  0.56
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