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Marina R. Picciotto - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Molecular Neurobiology, Molecular basis of behavior
Website:
http://info.med.yale.edu/psych/faculty/picciotto.html
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257 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rajebhosale P, Ananth MR, Kim R, Crouse R, Jiang L, López-Hernández G, Zhong C, Arty C, Wang S, Jone A, Desai NS, Li Y, Picciotto MR, Role LW, Talmage DA. Functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons. Research Square. PMID 38405824 DOI: 10.21203/rs.3.rs-3938016/v1  0.801
2024 Rajebhosale P, Ananth MR, Kim R, Crouse RB, Jiang L, López-Hernández G, Zhong C, Arty C, Wang S, Jone A, Desai NS, Li Y, Picciotto MR, Role LW, Talmage DA. Functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons. Elife. 13. PMID 38363713 DOI: 10.7554/eLife.86581  0.801
2024 Peltier MR, Verplaetse TL, Altemus M, Zakiniaeiz Y, Ralevski EA, Mineur YS, Gueorguieva R, Picciotto MR, Cosgrove KP, Petrakis I, McKee SA. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers in Neuroendocrinology. 101119. PMID 38184208 DOI: 10.1016/j.yfrne.2023.101119  0.548
2023 Kim K, Picciotto MR. Nicotine addiction: More than just dopamine. Current Opinion in Neurobiology. 83: 102797. PMID 37832393 DOI: 10.1016/j.conb.2023.102797  0.345
2023 Abdulla ZI, Mineur YS, Crouse RB, Etherington IM, Yousuf H, Na JJ, Picciotto MR. Acetylcholine signaling in the medial prefrontal cortex mediates the ability to learn an active avoidance response following learned helplessness training. Biorxiv : the Preprint Server For Biology. PMID 37790481 DOI: 10.1101/2023.09.23.559126  0.801
2023 Soares AR, Picciotto MR. Nicotinic regulation of microglia: potential contributions to addiction. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 37778006 DOI: 10.1007/s00702-023-02703-9  0.341
2023 Mineur YS, Picciotto MR. How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches. Journal of Neurochemistry. PMID 37621094 DOI: 10.1111/jnc.15943  0.617
2023 Zakiniaeiz Y, Peltier MR, Mineur YS, Gueorguieva R, Picciotto MR, Petrakis I, Cosgrove KP, McKee SA. Developing Researchers with Expertise in Sex as a Biological Variable through SCORE Career Enhancement Core Center Programs. Journal of Women's Health (2002). 32: 852-857. PMID 37585509 DOI: 10.1089/jwh.2023.0015  0.536
2023 Mineur YS, Soares AR, Etherington IM, Abdulla ZI, Picciotto MR. Pathophysiology of nAChRs: Limbic circuits and related disorders. Pharmacological Research. 191: 106745. PMID 37011774 DOI: 10.1016/j.phrs.2023.106745  0.636
2022 Yousuf H, Girardi EM, Crouse RB, Picciotto MR. Muscarinic antagonists impair multiple aspects of operant discrimination learning and performance. Neuroscience Letters. 794: 137025. PMID 36529388 DOI: 10.1016/j.neulet.2022.137025  0.787
2022 Zhou WL, Kim K, Ali F, Pittenger ST, Calarco CA, Mineur YS, Ramakrishnan C, Deisseroth K, Kwan AC, Picciotto MR. Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward. Science Advances. 8: eabm5217. PMID 36260661 DOI: 10.1126/sciadv.abm5217  0.791
2022 Mineur YS, Mose TN, Maibom KL, Pittenger ST, Soares AR, Wu H, Taylor SR, Huang Y, Picciotto MR. ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms. Molecular Psychiatry. PMID 36050437 DOI: 10.1038/s41380-022-01749-7  0.749
2022 Bagdas D, Kebede N, Zepei AM, Harris L, Minanov K, Picciotto MR, Addy NA. Animal models to investigate the impact of flavors on nicotine addiction and dependence. Current Neuropharmacology. PMID 35611777 DOI: 10.2174/1570159X20666220524120231  0.689
2022 Lee B, Pothula S, Wu M, Kang H, Girgenti MJ, Picciotto MR, DiLeone RJ, Taylor JR, Duman RS. Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear. Molecular Psychiatry. PMID 35418600 DOI: 10.1038/s41380-022-01498-7  0.493
2022 Mineur YS, Garcia-Rivas V, Thomas MA, Soares AR, McKee SA, Picciotto MR. Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways. Psychopharmacology. PMID 35359158 DOI: 10.1007/s00213-022-06120-w  0.571
2022 Mineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR. Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. Molecular Psychiatry. PMID 34997190 DOI: 10.1038/s41380-021-01404-7  0.812
2021 Lee AM, Mansuri MS, Wilson RS, Lam TT, Nairn AC, Picciotto MR. Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. Frontiers in Molecular Neuroscience. 14: 657064. PMID 34335180 DOI: 10.3389/fnmol.2021.657064  0.654
2021 Lee AM, Picciotto MR. Effects of nicotine on DARPP-32 and CaMKII signaling relevant to addiction. Advances in Pharmacology (San Diego, Calif.). 90: 89-115. PMID 33706940 DOI: 10.1016/bs.apha.2020.09.002  0.33
2021 Peltier MR, Verplaetse TL, Mineur YS, Geuorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology. 108499. PMID 33600842 DOI: 10.1016/j.neuropharm.2021.108499  0.556
2020 George AA, Vieira JM, Xavier-Jackson C, Gee MT, Cirrito JR, Bimonte-Nelson H, Picciotto MR, Lukas RJ, Whiteaker P. Implications of oligomeric amyloid-beta (oAβ42) signaling through α7β2-nicotinic acetylcholine receptors (nAChR) on basal forebrain cholinergic neuronal intrinsic excitability and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33239400 DOI: 10.1523/JNEUROSCI.0876-20.2020  0.301
2020 Qing H, Desrouleaux R, Israni-Winger K, Mineur YS, Fogelman N, Zhang C, Rashed S, Palm NW, Sinha R, Picciotto MR, Perry RJ, Wang A. Origin and Function of Stress-Induced IL-6 in Murine Models. Cell. 182: 1660. PMID 32946784 DOI: 10.1016/j.cell.2020.08.044  0.539
2020 Crouse RB, Kim K, Batchelor HM, Girardi EM, Kamaletdinova R, Chan J, Rajebhosale P, Pittenger ST, Role LW, Talmage DA, Jing M, Li Y, Gao XB, Mineur YS, Picciotto MR. Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances learning of cue-reward contingency. Elife. 9. PMID 32945260 DOI: 10.7554/Elife.57335  0.802
2020 Cope ZA, Lavadia ML, Joosen AJM, van de Cappelle CJA, Lara JC, Huval A, Kwiatkowski MK, Picciotto MR, Mineur YS, Dulcis D, Young JW. Converging evidence that short-active photoperiod increases acetylcholine signaling in the hippocampus. Cognitive, Affective & Behavioral Neuroscience. PMID 32794101 DOI: 10.3758/S13415-020-00824-2  0.703
2020 Qing H, Desrouleaux R, Israni-Winger K, Mineur YS, Fogelman N, Zhang C, Rashed S, Palm NW, Sinha R, Picciotto MR, Perry RJ, Wang A. Origin and Function of Stress-Induced IL-6 in Murine Models. Cell. PMID 32610084 DOI: 10.1016/J.Cell.2020.05.054  0.602
2020 Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajos M, Lu L, de Lecea L, de Araujo I, Picciotto M, Horvath TL, et al. Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. The Journal of Clinical Investigation. PMID 32516139 DOI: 10.1172/Jci130889  0.534
2020 Mineur YS, Ernsten C, Islam A, Maibom KL, Picciotto MR. Hippocampal knockdown of α2 nicotinic or m1 muscarinic acetylcholine receptors in C57BL/6j male mice impairs cued fear conditioning. Genes, Brain, and Behavior. e12677. PMID 32447811 DOI: 10.1111/gbb.12677  0.677
2020 Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harbor Perspectives in Medicine. PMID 32341069 DOI: 10.1101/cshperspect.a039610  0.41
2020 Taylor JR, DiLeone RJ, Picciotto MR. Ronald S. Duman, PhD (1954-2020). Nature Neuroscience. PMID 32313268 DOI: 10.1038/s41593-020-0629-3  0.459
2020 Barthas F, Hu MY, Siniscalchi MJ, Ali F, Mineur YS, Picciotto MR, Kwan AC. Cumulative Effects of Social Stress on Reward-Guided Actions and Prefrontal Cortical Activity. Biological Psychiatry. PMID 32276717 DOI: 10.1016/J.Biopsych.2020.02.008  0.624
2020 Krystal JH, Nestler EJ, Picciotto MR. Ronald S. Duman, Ph.D. (1954-2020). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32076104 DOI: 10.1038/S41386-020-0642-Y  0.48
2019 Lewis AS, Picciotto MR. Regulation of aggressive behaviors by nicotinic acetylcholine receptors: Animal models, human genetics, and clinical studies. Neuropharmacology. 167: 107929. PMID 32058178 DOI: 10.1016/j.neuropharm.2019.107929  0.419
2019 Mineur YS, Picciotto MR. The role of acetylcholine in negative encoding bias: Too much of a good thing? The European Journal of Neuroscience. PMID 31821620 DOI: 10.1111/ejn.14641  0.652
2019 Gerhard DM, Pothula S, Liu RJ, Wu M, Li XY, Girgenti MJ, Taylor SR, Duman CH, Delpire E, Picciotto M, Wohleb ES, Duman RS. GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions. The Journal of Clinical Investigation. PMID 31743111 DOI: 10.1172/Jci130808  0.598
2019 Lee AM, Calarco CA, McKee SA, Mineur YS, Picciotto MR. Variability in nicotine conditioned place preference, stress-induced reinstatement, and effects of guanfacine in male and female mice. Genes, Brain, and Behavior. e12601. PMID 31364813 DOI: 10.1111/gbb.12601  0.822
2019 Zakiniaeiz Y, Hillmer AT, Matuskey D, Nabulsi N, Ropchan J, Mazure CM, Picciotto MR, Huang Y, McKee SA, Morris ED, Cosgrove KP. Sex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31269510 DOI: 10.1038/S41386-019-0456-Y  0.319
2019 Lee AM, Picciotto MR. Perinatal nicotine exposure impairs learning of a skilled forelimb reaching task in male but not female adult mice. Behavioural Brain Research. PMID 30959127 DOI: 10.1016/j.bbr.2019.04.007  0.416
2019 Peltier MR, Verplaetse TL, Mineur YS, Petrakis IL, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in stress-related alcohol use. Neurobiology of Stress. 10: 100149. PMID 30949562 DOI: 10.1016/j.ynstr.2019.100149  0.602
2019 Calarco CA, Picciotto MR. Nicotinic acetylcholine receptor signaling in the hypothalamus: mechanisms related to nicotine's effects on food intake. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 30690485 DOI: 10.1093/ntr/ntz010  0.801
2019 Deyama S, Bang E, Wohleb ES, Li XY, Kato T, Gerhard DM, Dutheil S, Dwyer JM, Taylor SR, Picciotto MR, Duman RS. Role of Neuronal VEGF Signaling in the Prefrontal Cortex in the Rapid Antidepressant Effects of Ketamine. The American Journal of Psychiatry. appiajp201817121368. PMID 30606046 DOI: 10.1176/Appi.Ajp.2018.17121368  0.568
2019 Picciotto M, Mineur Y. Cholinergic modulation of circuits involved in stress-related behaviors Ibro Reports. 6: S28. DOI: 10.1016/j.ibror.2019.07.080  0.621
2018 Miller MB, Wilson RS, Lam TT, Nairn AC, Picciotto MR. Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo. Proteomes. 6. PMID 30326594 DOI: 10.3390/Proteomes6040042  0.648
2018 Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, ... ... Picciotto MR, et al. The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. Cell. PMID 30318146 DOI: 10.1016/J.Cell.2018.09.014  0.673
2018 Li D, Musante V, Zhou WL, Picciotto MR, Nairn AC. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. The Journal of Biological Chemistry. PMID 29802198 DOI: 10.1074/jbc.RA117.001519  0.683
2018 Calarco CA, Li Z, Taylor SR, Lee S, Zhou W, Friedman JM, Mineur YS, Gotti C, Picciotto MR. Molecular and cellular characterization of nAChR subtypes in the arcuate nucleus of the mouse hypothalamus. The European Journal of Neuroscience. PMID 29791746 DOI: 10.1111/Ejn.13966  0.821
2018 Lewis AS, van Schalkwyk GI, Lopez MO, Volkmar FR, Picciotto MR, Sukhodolsky DG. An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. PMID 29536216 DOI: 10.1007/S10803-018-3536-7  0.4
2018 Mineur YS, Cahuzac EL, Mose TN, Bentham MP, Plantenga ME, Thompson DC, Picciotto MR. Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29472646 DOI: 10.1038/s41386-018-0024-x  0.712
2017 Lewis AS, Pittenger ST, Mineur YS, Stout D, Smith PH, Picciotto MR. Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29114104 DOI: 10.1038/npp.2017.276  0.707
2017 Sandiego CM, Matuskey D, Lavery M, McGovern E, Huang Y, Nabulsi N, Ropchan J, Picciotto MR, Morris ED, McKee SA, Cosgrove KP. The Effect of Treatment with Guanfacine, an alpha2 Adrenergic Agonist, on Dopaminergic Tone in Tobacco Smokers: An [(11)C]FLB457 PET Study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28944773 DOI: 10.1038/Npp.2017.223  0.322
2017 Fait BW, Thompson D, Mose T, Jatlow P, Jordt S, Picciotto MR, Mineur YS. Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice. Behavioural Brain Research. PMID 28743602 DOI: 10.1016/j.bbr.2017.07.027  0.715
2017 Jung Y, Lee AM, McKee SA, Picciotto MR. Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators. Scientific Reports. 7: 4315. PMID 28659613 DOI: 10.1038/s41598-017-04413-1  0.751
2017 Calarco CA, Lee S, Picciotto MR. Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice. Neuropharmacology. PMID 28623168 DOI: 10.1016/j.neuropharm.2017.06.012  0.811
2017 Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal of Psychopharmacology (Oxford, England). 269881117699603. PMID 28440105 DOI: 10.1177/0269881117699603  0.31
2017 Mineur YS, Mose TN, Blakeman S, Picciotto MR. Hippocampal α7 nicotinic acetylcholine receptors contribute to modulation of depression-like behavior in C57BL/6 J mice. British Journal of Pharmacology. PMID 28264149 DOI: 10.1111/bph.13769  0.69
2016 Fan L, Balakrishna S, Jabba SV, Bonner PE, Taylor SR, Picciotto MR, Jordt SE. Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism. Tobacco Control. PMID 27698211 DOI: 10.1136/Tobaccocontrol-2016-053209  0.769
2016 Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S. CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory. Neuron. PMID 27667007 DOI: 10.1016/J.Neuron.2016.09.002  0.636
2016 Esterlis I, Hillmer AT, Bois F, Pittman B, McGovern E, O'Malley SS, Picciotto MR, Yang BZ, Gelernter J, Cosgrove KP. CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 27611310 DOI: 10.1093/Ntr/Ntw081  0.38
2016 McClure-Begley TD, Esterlis I, Stone KL, Lam TT, Grady SR, Colangelo CM, Lindstrom JM, Marks MJ, Picciotto MR. Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex. Eneuro. 3. PMID 27559543 DOI: 10.1523/ENEURO.0166-16.2016  0.344
2016 Wohleb ES, Wu M, Gerhard DM, Taylor SR, Picciotto MR, Alreja M, Duman RS. GABA interneurons mediate the rapid antidepressant-like effects of scopolamine. The Journal of Clinical Investigation. PMID 27270172 DOI: 10.1172/Jci85033  0.616
2016 Jung Y, Hsieh LS, Lee AM, Zhou Z, Coman D, Heath CJ, Hyder F, Mineur YS, Yuan Q, Goldman D, Bordey A, Picciotto MR. An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior. Nature Neuroscience. PMID 27239938 DOI: 10.1038/Nn.4315  0.824
2015 Engmann O, Giralt A, Gervasi N, Marion-Poll L, Gasmi L, Filhol O, Picciotto MR, Gilligan D, Greengard P, Nairn AC, Hervé D, Girault JA. DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nature Communications. 6: 10099. PMID 26639316 DOI: 10.1038/ncomms10099  0.743
2015 Mineur YS, Fote GM, Blakeman S, Cahuzac EL, Newbold SA, Picciotto MR. Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26471256 DOI: 10.1038/npp.2015.316  0.687
2015 Zhou WL, Gao XB, Picciotto MR. Acetylcholine Acts through Nicotinic Receptors to Enhance the Firing Rate of a Subset of Hypocretin Neurons in the Mouse Hypothalamus through Distinct Presynaptic and Postsynaptic Mechanisms(.) Eneuro. 2. PMID 26322330 DOI: 10.1523/ENEURO.0052-14.2015  0.541
2015 Lewis AS, Mineur YS, Smith PH, Cahuzac EL, Picciotto MR. Modulation of aggressive behavior in mice by nicotinic receptor subtypes. Biochemical Pharmacology. PMID 26212554 DOI: 10.1016/j.bcp.2015.07.019  0.716
2015 Mineur YS, Bentham MP, Zhou WL, Plantenga ME, McKee SA, Picciotto MR. Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice. Psychopharmacology. PMID 26146014 DOI: 10.1007/s00213-015-4001-3  0.718
2015 Van Schalkwyk GI, Lewis AS, Qayyum Z, Koslosky K, Picciotto MR, Volkmar FR. Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 45: 3061-6. PMID 25982311 DOI: 10.1007/S10803-015-2471-0  0.394
2015 Verplaetse TL, Weinberger AH, Smith PH, Cosgrove KP, Mineur YS, Picciotto MR, Mazure CM, McKee SA. Targeting the noradrenergic system for gender-sensitive medication development for tobacco dependence. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 17: 486-95. PMID 25762760 DOI: 10.1093/ntr/ntu280  0.603
2015 Picciotto MR, Lewis AS, van Schalkwyk GI, Mineur YS. Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states. Neuropharmacology. 96: 235-43. PMID 25582289 DOI: 10.1016/j.neuropharm.2014.12.028  0.702
2015 McKee SA, Potenza MN, Kober H, Sofuoglu M, Arnsten AF, Picciotto MR, Weinberger AH, Ashare R, Sinha R. A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation. Journal of Psychopharmacology (Oxford, England). 29: 300-11. PMID 25516371 DOI: 10.1177/0269881114562091  0.31
2015 Mineur YS, Einstein EB, Bentham MP, Wigestrand MB, Blakeman S, Newbold SA, Picciotto MR. Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 938-46. PMID 25288485 DOI: 10.1038/Npp.2014.269  0.819
2015 Lewis AS, Garvey K, Mineur YS, Picciotto MR. Reduction of aggressive behavior in mouse models by the selective α7 nicotinic partial agonist GTS-21 Biochemical Pharmacology. 97: 632-633. DOI: 10.1016/J.BCP.2015.08.034  0.672
2015 Lewis AS, Mineur YS, Smith PH, Cahuzac ELM, Picciotto MR. Modulation of aggressive behavior in mice by nicotinic receptor subtypes Biochemical Pharmacology. DOI: 10.1016/j.bcp.2015.07.019  0.683
2014 Higley MJ, Picciotto MR. Neuromodulation by acetylcholine: examples from schizophrenia and depression. Current Opinion in Neurobiology. 29: 88-95. PMID 24983212 DOI: 10.1016/j.conb.2014.06.004  0.317
2014 Mazei-Robison MS, Appasani R, Edwards S, Wee S, Taylor SR, Picciotto MR, Koob GF, Nestler EJ. Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons. Plos One. 9: e95962. PMID 24755634 DOI: 10.1371/Journal.Pone.0095962  0.722
2014 Mineur YS, Taylor SR, Picciotto MR. Calcineurin downregulation in the amygdala is sufficient to induce anxiety-like and depression-like behaviors in C57BL/6J male mice. Biological Psychiatry. 75: 991-8. PMID 24742621 DOI: 10.1016/J.Biopsych.2014.03.009  0.728
2014 Taylor SR, Badurek S, Dileone RJ, Nashmi R, Minichiello L, Picciotto MR. GABAergic and glutamatergic efferents of the mouse ventral tegmental area. The Journal of Comparative Neurology. 522: 3308-34. PMID 24715505 DOI: 10.1002/Cne.23603  0.585
2014 McClure-Begley TD, Papke RL, Stone KL, Stokes C, Levy AD, Gelernter J, Xie P, Lindstrom J, Picciotto MR. Rare human nicotinic acetylcholine receptor α4 subunit (CHRNA4) variants affect expression and function of high-affinity nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 348: 410-20. PMID 24385388 DOI: 10.1124/Jpet.113.209767  0.465
2014 Esterlis I, Ranganathan M, Bois F, Pittman B, Picciotto MR, Shearer L, Anticevic A, Carlson J, Niciu MJ, Cosgrove KP, D'Souza DC. In vivo evidence for β2 nicotinic acetylcholine receptor subunit upregulation in smokers as compared with nonsmokers with schizophrenia. Biological Psychiatry. 76: 495-502. PMID 24360979 DOI: 10.1016/J.Biopsych.2013.11.001  0.361
2014 Park A, O'Malley SS, King SL, Picciotto MR. Mediating role of stress reactivity in the effects of prenatal tobacco exposure on childhood mental health outcomes. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 16: 174-85. PMID 23990474 DOI: 10.1093/ntr/ntt131  0.61
2014 Picciotto MR, Mineur YS. Molecules and circuits involved in nicotine addiction: The many faces of smoking. Neuropharmacology. 76: 545-53. PMID 23632083 DOI: 10.1016/j.neuropharm.2013.04.028  0.659
2014 Steiner RC, Picciotto MR. Drug abuse: Nicotine Behavioral Genetics of the Mouse Volume Ii: Genetic Mouse Models of Neurobehavioral Disorders. 303-314. DOI: 10.1007/CBO9781107360556  0.802
2013 Peng C, Stokes C, Mineur YS, Picciotto MR, Tian C, Eibl C, Tomassoli I, Guendisch D, Papke RL. Differential modulation of brain nicotinic acetylcholine receptor function by cytisine, varenicline, and two novel bispidine compounds: emergent properties of a hybrid molecule. The Journal of Pharmacology and Experimental Therapeutics. 347: 424-37. PMID 23959137 DOI: 10.1124/jpet.113.206904  0.708
2013 McClure-Begley TD, Stone KL, Marks MJ, Grady SR, Colangelo CM, Lindstrom JM, Picciotto MR. Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice. Genomics, Proteomics & Bioinformatics. 11: 207-18. PMID 23891776 DOI: 10.1016/J.Gpb.2013.05.005  0.465
2013 Yang Y, Paspalas CD, Jin LE, Picciotto MR, Arnsten AF, Wang M. Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 110: 12078-83. PMID 23818597 DOI: 10.1073/Pnas.1307849110  0.375
2013 Hannestad JO, Cosgrove KP, DellaGioia NF, Perkins E, Bois F, Bhagwagar Z, Seibyl JP, McClure-Begley TD, Picciotto MR, Esterlis I. Changes in the cholinergic system between bipolar depression and euthymia as measured with [123I]5IA single photon emission computed tomography. Biological Psychiatry. 74: 768-76. PMID 23773793 DOI: 10.1016/J.Biopsych.2013.04.004  0.312
2013 Neugebauer NM, Einstein EB, Lopez MB, McClure-Begley TD, Mineur YS, Picciotto MR. Morphine dependence and withdrawal induced changes in cholinergic signaling. Pharmacology, Biochemistry, and Behavior. 109: 77-83. PMID 23651795 DOI: 10.1016/J.Pbb.2013.04.015  0.823
2013 Lewis AS, Picciotto MR. High-affinity nicotinic acetylcholine receptor expression and trafficking abnormalities in psychiatric illness. Psychopharmacology. 229: 477-85. PMID 23624811 DOI: 10.1007/s00213-013-3126-5  0.428
2013 Picciotto MR. An indirect resilience to addiction. Nature Neuroscience. 16: 521-3. PMID 23619754 DOI: 10.1038/nn.3375  0.31
2013 Mineur YS, Obayemi A, Wigestrand MB, Fote GM, Calarco CA, Li AM, Picciotto MR. Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 110: 3573-8. PMID 23401542 DOI: 10.1073/Pnas.1219731110  0.809
2013 Einstein EB, Asaka Y, Yeckel MF, Higley MJ, Picciotto MR. Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and morphine conditioned place preference require both galanin receptor 1 and galanin receptor 2. The European Journal of Neuroscience. 37: 1541-9. PMID 23387435 DOI: 10.1111/ejn.12151  0.811
2013 Addy NA, Picciotto MR. Nicotine, striatum, and reward. Biological Psychiatry. 73: 205-6. PMID 23337022 DOI: 10.1016/j.biopsych.2012.11.001  0.727
2013 Rao Y, Mineur YS, Gan G, Wang AH, Liu ZW, Wu X, Suyama S, de Lecea L, Horvath TL, Picciotto MR, Gao XB. Repeated in vivo exposure of cocaine induces long-lasting synaptic plasticity in hypocretin/orexin-producing neurons in the lateral hypothalamus in mice. The Journal of Physiology. 591: 1951-66. PMID 23318871 DOI: 10.1113/jphysiol.2012.246983  0.715
2013 Giza JI, Jung Y, Jeffrey RA, Neugebauer NM, Picciotto MR, Biederer T. The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 628-38. PMID 23169347 DOI: 10.1038/Npp.2012.226  0.793
2013 Esterlis I, Hannestad JO, Bois F, Sewell RA, Tyndale RF, Seibyl JP, Picciotto MR, Laruelle M, Carson RE, Cosgrove KP. Imaging changes in synaptic acetylcholine availability in living human subjects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 78-82. PMID 23160789 DOI: 10.2967/Jnumed.112.111922  0.389
2013 Picciotto MR, Mineur YS. Nicotine, food intake, and activation of POMC neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 245. PMID 23147487 DOI: 10.1038/npp.2012.163  0.62
2013 Picciotto MR, Kenny PJ. Molecular mechanisms underlying behaviors related to nicotine addiction. Cold Spring Harbor Perspectives in Medicine. 3: a012112. PMID 23143843 DOI: 10.1101/cshperspect.a012112  0.441
2013 Jung Y, Mulholland PJ, Wiseman SL, Chandler LJ, Picciotto MR. Constitutive knockout of the membrane cytoskeleton protein beta adducin decreases mushroom spine density in the nucleus accumbens but does not prevent spine remodeling in response to cocaine. The European Journal of Neuroscience. 37: 1-9. PMID 23106536 DOI: 10.1111/Ejn.12037  0.778
2012 Picciotto MR, Higley MJ, Mineur YS. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 76: 116-29. PMID 23040810 DOI: 10.1016/j.neuron.2012.08.036  0.677
2012 DiLeone RJ, Taylor JR, Picciotto MR. The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction. Nature Neuroscience. 15: 1330-5. PMID 23007187 DOI: 10.1038/nn.3202  0.493
2012 Zoli M, Picciotto MR. Nicotinic regulation of energy homeostasis. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1270-90. PMID 22990212 DOI: 10.1093/ntr/nts159  0.416
2012 Saricicek A, Esterlis I, Maloney KH, Mineur YS, Ruf BM, Muralidharan A, Chen JI, Cosgrove KP, Kerestes R, Ghose S, Tamminga CA, Pittman B, Bois F, Tamagnan G, Seibyl J, ... Picciotto MR, et al. Persistent β2*-nicotinic acetylcholinergic receptor dysfunction in major depressive disorder. The American Journal of Psychiatry. 169: 851-9. PMID 22772158 DOI: 10.1176/Appi.Ajp.2012.11101546  0.65
2012 Dietrich MO, Bober J, Ferreira JG, Tellez LA, Mineur YS, Souza DO, Gao XB, Picciotto MR, Araújo I, Liu ZW, Horvath TL. AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors. Nature Neuroscience. 15: 1108-10. PMID 22729177 DOI: 10.1038/Nn.3147  0.714
2012 Cosgrove KP, Esterlis I, McKee SA, Bois F, Seibyl JP, Mazure CM, Krishnan-Sarin S, Staley JK, Picciotto MR, O'Malley SS. Sex differences in availability of β2*-nicotinic acetylcholine receptors in recently abstinent tobacco smokers. Archives of General Psychiatry. 69: 418-27. PMID 22474108 DOI: 10.1001/Archgenpsychiatry.2011.1465  0.369
2012 Horst NK, Heath CJ, Neugebauer NM, Kimchi EY, Laubach M, Picciotto MR. Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletion. Behavioural Brain Research. 231: 170-80. PMID 22433585 DOI: 10.1016/J.Bbr.2012.03.002  0.811
2012 Yan Y, Pushparaj A, Gamaleddin I, Steiner RC, Picciotto MR, Roder J, Le Foll B. Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction. Behavioural Brain Research. 230: 34-9. PMID 22326373 DOI: 10.1016/J.Bbr.2012.01.042  0.832
2012 Holmes FE, Armenaki A, Iismaa TP, Einstein EB, Shine J, Picciotto MR, Wynick D, Zachariou V. Galanin negatively modulates opiate withdrawal via galanin receptor 1. Psychopharmacology. 220: 619-25. PMID 21969124 DOI: 10.1007/S00213-011-2515-X  0.807
2012 Guez-Barber D, Fanous S, Harvey BK, Zhang Y, Lehrmann E, Becker KG, Picciotto MR, Hope BT. FACS purification of immunolabeled cell types from adult rat brain. Journal of Neuroscience Methods. 203: 10-8. PMID 21911005 DOI: 10.1016/J.Jneumeth.2011.08.045  0.78
2012 L. Papke R, Picciotto M. Nicotine Dependence and Depression, What is the Future for Therapeutics? Journal of Addiction Research & Therapy. 3. DOI: 10.4172/2155-6105.1000E105  0.35
2011 Tian MK, Bailey CD, De Biasi M, Picciotto MR, Lambe EK. Plasticity of prefrontal attention circuitry: upregulated muscarinic excitability in response to decreased nicotinic signaling following deletion of α5 or β2 subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16458-63. PMID 22072695 DOI: 10.1523/JNEUROSCI.3600-11.2011  0.462
2011 Wigestrand MB, Mineur YS, Heath CJ, Fonnum F, Picciotto MR, Walaas SI. Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post-transcriptional regulation in the spontaneously hypertensive rat model of ADHD. Journal of Neurochemistry. 119: 240-50. PMID 21824140 DOI: 10.1111/J.1471-4159.2011.07415.X  0.807
2011 Yalcin I, Charlet A, Cordero-Erausquin M, Tessier LH, Picciotto MR, Schlichter R, Poisbeau P, Freund-Mercier MJ, Barrot M. Nociceptive thresholds are controlled through spinal β2-subunit-containing nicotinic acetylcholine receptors. Pain. 152: 2131-7. PMID 21794985 DOI: 10.1016/J.Pain.2011.05.022  0.813
2011 Abizaid A, Mineur YS, Roth RH, Elsworth JD, Sleeman MW, Picciotto MR, Horvath TL. Reduced locomotor responses to cocaine in ghrelin-deficient mice. Neuroscience. 192: 500-6. PMID 21699961 DOI: 10.1016/J.Neuroscience.2011.06.001  0.715
2011 Xu HP, Furman M, Mineur YS, Chen H, King SL, Zenisek D, Zhou ZJ, Butts DA, Tian N, Picciotto MR, Crair MC. An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron. 70: 1115-27. PMID 21689598 DOI: 10.1016/j.neuron.2011.04.028  0.762
2011 Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J. Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biological Psychiatry. 70: 528-36. PMID 21683344 DOI: 10.1016/J.Biopsych.2011.04.017  0.344
2011 Mineur YS, Abizaid A, Rao Y, Salas R, DiLeone RJ, Gündisch D, Diano S, De Biasi M, Horvath TL, Gao XB, Picciotto MR. Nicotine decreases food intake through activation of POMC neurons. Science (New York, N.Y.). 332: 1330-2. PMID 21659607 DOI: 10.1126/Science.1201889  0.74
2011 Mineur YS, Einstein EB, Seymour PA, Coe JW, O'neill BT, Rollema H, Picciotto MR. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behavioural Pharmacology. 22: 291-9. PMID 21566524 DOI: 10.1097/FBP.0b013e328347546d  0.803
2011 Venkitaramani DV, Moura PJ, Picciotto MR, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory. The European Journal of Neuroscience. 33: 2288-98. PMID 21501258 DOI: 10.1111/j.1460-9568.2011.07687.x  0.607
2011 Caldarone BJ, Wang D, Paterson NE, Manzano M, Fedolak A, Cavino K, Kwan M, Hanania T, Chellappan SK, Kozikowski AP, Olivier B, Picciotto MR, Ghavami A. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380. Psychopharmacology. 217: 199-210. PMID 21487659 DOI: 10.1007/S00213-011-2271-Y  0.695
2011 Lori A, Tang Y, O'Malley S, Picciotto MR, Wu R, Conneely KN, Cubells JF. The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1412-20. PMID 21430647 DOI: 10.1038/Npp.2011.25  0.329
2011 Guez-Barber D, Fanous S, Golden SA, Schrama R, Koya E, Stern AL, Bossert JM, Harvey BK, Picciotto MR, Hope BT. FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4251-9. PMID 21411666 DOI: 10.1523/Jneurosci.6195-10.2011  0.792
2011 Neugebauer NM, Henehan RM, Hales CA, Picciotto MR. Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference. Pharmacology, Biochemistry, and Behavior. 98: 87-93. PMID 21172385 DOI: 10.1016/J.Pbb.2010.12.015  0.786
2011 Esterlis I, Mitsis EM, Batis JC, Bois F, Picciotto MR, Stiklus SM, Kloczynski T, Perry E, Seibyl JP, McKee S, Staley JK, Cosgrove KP. Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 389-98. PMID 21029513 DOI: 10.1017/S1461145710001227  0.428
2011 Tomassoli I, Eibl C, Wulf M, Papke R, Picciotto M, Gündisch D. The twin drug approach for novel nicotinic acetylcholine receptor (nAChR) ligands: Synthesis and structure–affinity relationships Biochemical Pharmacology. 82: 1028. DOI: 10.1016/J.BCP.2011.07.016  0.376
2010 Picciotto MR. Galanin and addiction. Exs. 102: 195-208. PMID 21299070 DOI: 10.1007/978-3-0346-0228-0_14  0.379
2010 Brabant C, Kuschpel AS, Picciotto MR. Locomotion and self-administration induced by cocaine in 129/OlaHsd mice lacking galanin. Behavioral Neuroscience. 124: 828-38. PMID 21038934 DOI: 10.1037/a0021221  0.339
2010 Mineur YS, Picciotto MR. Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis. Trends in Pharmacological Sciences. 31: 580-6. PMID 20965579 DOI: 10.1016/j.tips.2010.09.004  0.688
2010 Kamens HM, Andersen J, Picciotto MR. The nicotinic acetylcholine receptor partial agonist varenicline increases the ataxic and sedative-hypnotic effects of acute ethanol administration in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 34: 2053-60. PMID 20946306 DOI: 10.1111/j.1530-0277.2010.01301.x  0.696
2010 Heath CJ, Horst NK, Picciotto MR. Oral nicotine consumption does not affect maternal care or early development in mice but results in modest hyperactivity in adolescence. Physiology & Behavior. 101: 764-9. PMID 20826170 DOI: 10.1016/j.physbeh.2010.08.021  0.826
2010 Heath CJ, King SL, Gotti C, Marks MJ, Picciotto MR. Cortico-thalamic connectivity is vulnerable to nicotine exposure during early postnatal development through α4/β2/α5 nicotinic acetylcholine receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2324-38. PMID 20736992 DOI: 10.1038/npp.2010.130  0.806
2010 Kamens HM, Andersen J, Picciotto MR. Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice. Psychopharmacology. 208: 613-26. PMID 20072781 DOI: 10.1007/s00213-009-1759-1  0.728
2010 Picciotto MR, Brabant C, Einstein EB, Kamens HM, Neugebauer NM. Effects of galanin on monoaminergic systems and HPA axis: Potential mechanisms underlying the effects of galanin on addiction- and stress-related behaviors. Brain Research. 1314: 206-18. PMID 19699187 DOI: 10.1016/J.Brainres.2009.08.033  0.791
2009 Mineur YS, Picciotto MR. Biological basis for the co-morbidity between smoking and mood disorders. Journal of Dual Diagnosis. 5: 122-130. PMID 20046987 DOI: 10.1080/15504260902869964  0.664
2009 Lavaur J, Mineur YS, Picciotto MR. The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration. Journal of Neurochemistry. 111: 1129-37. PMID 19780900 DOI: 10.1111/j.1471-4159.2009.06405.x  0.646
2009 Bahi A, Mineur YS, Picciotto MR. Blockade of protein phosphatase 2B activity in the amygdala increases anxiety- and depression-like behaviors in mice. Biological Psychiatry. 66: 1139-46. PMID 19716552 DOI: 10.1016/j.biopsych.2009.07.004  0.64
2009 Brunzell DH, Mineur YS, Neve RL, Picciotto MR. Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1993-2001. PMID 19212318 DOI: 10.1038/npp.2009.11  0.834
2009 Rollema H, Guanowsky V, Mineur YS, Shrikhande A, Coe JW, Seymour PA, Picciotto MR. Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect. European Journal of Pharmacology. 605: 114-6. PMID 19168054 DOI: 10.1016/j.ejphar.2009.01.002  0.68
2009 Mineur YS, Eibl C, Young G, Kochevar C, Papke RL, Gündisch D, Picciotto MR. Cytisine-based nicotinic partial agonists as novel antidepressant compounds. The Journal of Pharmacology and Experimental Therapeutics. 329: 377-86. PMID 19164465 DOI: 10.1124/jpet.108.149609  0.703
2009 Narasimhaiah R, Kamens HM, Picciotto MR. Effects of galanin on cocaine-mediated conditioned place preference and ERK signaling in mice. Psychopharmacology. 204: 95-102. PMID 19099295 DOI: 10.1007/s00213-008-1438-7  0.808
2009 Mineur YS, Brunzell DH, Grady SR, Lindstrom JM, McIntosh JM, Marks MJ, King SL, Picciotto MR. Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning. Genes, Brain, and Behavior. 8: 257-66. PMID 19077117 DOI: 10.1111/J.1601-183X.2008.00468.X  0.844
2009 Jacobsen LK, Picciotto MR, Heath CJ, Mencl WE, Gelernter J. Allelic variation of calsyntenin 2 (CLSTN2) modulates the impact of developmental tobacco smoke exposure on mnemonic processing in adolescents. Biological Psychiatry. 65: 671-9. PMID 19058786 DOI: 10.1016/J.Biopsych.2008.10.024  0.62
2009 Brunzell DH, Picciotto MR. Molecular mechanisms underlying the motivational effects of nicotine. Nebraska Symposium On Motivation. Nebraska Symposium On Motivation. 55: 17-30. PMID 19013937 DOI: 10.1007/978-0-387-78748-0_3  0.754
2009 Venkitaramani DV, Paul S, Zhang Y, Kurup P, Ding L, Tressler L, Allen M, Sacca R, Picciotto MR, Lombroso PJ. Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation. Synapse (New York, N.Y.). 63: 69-81. PMID 18932218 DOI: 10.1002/syn.20608  0.621
2009 Rudnick ND, Koehler C, Picciotto MR, Siegel SJ. Role of beta2-containing nicotinic acetylcholine receptors in auditory event-related potentials. Psychopharmacology. 202: 745-51. PMID 18931833 DOI: 10.1007/s00213-008-1358-6  0.447
2009 Brabant C, Alleva L, Grisar T, Quertemont E, Lakaye B, Ohtsu H, Lin JS, Jatlow P, Picciotto MR, Tirelli E. Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions. Psychopharmacology. 202: 673-87. PMID 18843481 DOI: 10.1007/s00213-008-1345-y  0.333
2009 Heath CJ, Picciotto MR. Nicotine-induced plasticity during development: modulation of the cholinergic system and long-term consequences for circuits involved in attention and sensory processing. Neuropharmacology. 56: 254-62. PMID 18692078 DOI: 10.1016/j.neuropharm.2008.07.020  0.688
2008 Rao Y, Lu M, Ge F, Marsh DJ, Qian S, Wang AH, Picciotto MR, Gao XB. Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9101-10. PMID 18784290 DOI: 10.1523/JNEUROSCI.1766-08.2008  0.41
2008 Addy NA, Bahi A, Taylor JR, Picciotto MR. Administration of the calcineurin inhibitor cyclosporine modulates cocaine-induced locomotor activity in rats. Psychopharmacology. 200: 129-39. PMID 18587562 DOI: 10.1007/s00213-008-1189-5  0.725
2008 Vieyra-Reyes P, Mineur YS, Picciotto MR, Túnez I, Vidaltamayo R, Drucker-Colín R. Antidepressant-like effects of nicotine and transcranial magnetic stimulation in the olfactory bulbectomy rat model of depression. Brain Research Bulletin. 77: 13-8. PMID 18582540 DOI: 10.1016/j.brainresbull.2008.05.007  0.647
2008 Caldarone BJ, King SL, Picciotto MR. Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice. Neuroscience Letters. 439: 187-91. PMID 18524488 DOI: 10.1016/j.neulet.2008.05.023  0.806
2008 Picciotto MR. Galanin and addiction. Cellular and Molecular Life Sciences : Cmls. 65: 1872-9. PMID 18500649 DOI: 10.1007/s00018-008-8151-x  0.378
2008 Vieyra-Reyes P, Picciotto MR, Mineur YS. Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors. Neuroscience Letters. 434: 18-22. PMID 18261852 DOI: 10.1016/j.neulet.2008.01.021  0.738
2008 Picciotto MR, Addy NA, Mineur YS, Brunzell DH. It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood. Progress in Neurobiology. 84: 329-42. PMID 18242816 DOI: 10.1016/j.pneurobio.2007.12.005  0.833
2008 Müller Smith K, Fagel DM, Stevens HE, Rabenstein RL, Maragnoli ME, Ohkubo Y, Picciotto MR, Schwartz ML, Vaccarino FM. Deficiency in inhibitory cortical interneurons associates with hyperactivity in fibroblast growth factor receptor 1 mutant mice. Biological Psychiatry. 63: 953-62. PMID 17988653 DOI: 10.1016/J.Biopsych.2007.09.020  0.797
2008 Picciotto MR, Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Frontiers in Bioscience : a Journal and Virtual Library. 13: 492-504. PMID 17981563 DOI: 10.2741/2695  0.432
2008 Hawes JJ, Brunzell DH, Narasimhaiah R, Langel U, Wynick D, Picciotto MR. Galanin protects against behavioral and neurochemical correlates of opiate reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1864-73. PMID 17957220 DOI: 10.1038/Sj.Npp.1301579  0.81
2008 Mineur YS, Picciotto MR. Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction. Biochemical Pharmacology. 75: 323-33. PMID 17632086 DOI: 10.1016/j.bcp.2007.06.010  0.709
2008 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Corrigendum to "prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors". [Neuroscience 147 (2007) 419-427] (DOI:10.1016/j.neuroscience.2007.04.036) Neuroscience. 156: 800. DOI: 10.1016/J.Neuroscience.2008.08.024  0.314
2007 Rao Y, Liu ZW, Borok E, Rabenstein RL, Shanabrough M, Lu M, Picciotto MR, Horvath TL, Gao XB. Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons. The Journal of Clinical Investigation. 117: 4022-33. PMID 18060037 DOI: 10.1172/JCI32829  0.787
2007 Jacobsen LK, Picciotto MR, Heath CJ, Frost SJ, Tsou KA, Dwan RA, Jackowski MP, Constable RT, Mencl WE. Prenatal and adolescent exposure to tobacco smoke modulates the development of white matter microstructure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13491-8. PMID 18057207 DOI: 10.1523/Jneurosci.2402-07.2007  0.632
2007 Addy NA, Fornasiero EF, Stevens TR, Taylor JR, Picciotto MR. Role of calcineurin in nicotine-mediated locomotor sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8571-80. PMID 17687035 DOI: 10.1523/Jneurosci.2601-07.2007  0.833
2007 Steiner RC, Heath CJ, Picciotto MR. Nicotine-induced phosphorylation of ERK in mouse primary cortical neurons: evidence for involvement of glutamatergic signaling and CaMKII. Journal of Neurochemistry. 103: 666-78. PMID 17666046 DOI: 10.1111/j.1471-4159.2007.04799.x  0.825
2007 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: role of autoreceptors. Neuroscience. 147: 419-27. PMID 17543464 DOI: 10.1016/J.Neuroscience.2007.04.036  0.326
2007 Uboha NV, Flajolet M, Nairn AC, Picciotto MR. A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4413-23. PMID 17442826 DOI: 10.1523/Jneurosci.0725-07.2007  0.781
2007 Mineur YS, Somenzi O, Picciotto MR. Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice. Neuropharmacology. 52: 1256-62. PMID 17320916 DOI: 10.1016/j.neuropharm.2007.01.006  0.697
2007 Lynch WJ, Kiraly DD, Caldarone BJ, Picciotto MR, Taylor JR. Effect of cocaine self-administration on striatal PKA-regulated signaling in male and female rats. Psychopharmacology. 191: 263-71. PMID 17180335 DOI: 10.1007/s00213-006-0656-0  0.703
2007 Zanetti L, Picciotto MR, Zoli M. Differential effects of nicotinic antagonists perfused into the nucleus accumbens or the ventral tegmental area on cocaine-induced dopamine release in the nucleus accumbens of mice. Psychopharmacology. 190: 189-99. PMID 17061109 DOI: 10.1007/s00213-006-0598-6  0.403
2007 Fornari A, Pedrazzi P, Lippi G, Picciotto MR, Zoli M, Zini I. Nicotine withdrawal increases body weight, neuropeptide Y and Agouti-related protein expression in the hypothalamus and decreases uncoupling protein-3 expression in the brown adipose tissue in high-fat fed mice. Neuroscience Letters. 411: 72-6. PMID 17052838 DOI: 10.1016/j.neulet.2006.10.014  0.41
2007 Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, ... ... Picciotto MR, et al. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology. 190: 269-319. PMID 16896961 DOI: 10.1007/S00213-006-0441-0  0.596
2007 Mineur YS, Picciotto MR, Sanacora G. Antidepressant-like effects of ceftriaxone in male C57BL/6J mice. Biological Psychiatry. 61: 250-2. PMID 16860779 DOI: 10.1016/j.biopsych.2006.04.037  0.642
2006 Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal of Clinical Investigation. 116: 3229-39. PMID 17060947 DOI: 10.1172/Jci29867  0.548
2006 Rabenstein RL, Caldarone BJ, Picciotto MR. The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacology. 189: 395-401. PMID 17016705 DOI: 10.1007/s00213-006-0568-z  0.826
2006 Cleary MA, Uboha N, Picciotto MR, Beech RD. Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream. Neuroscience. 143: 851-61. PMID 16996217 DOI: 10.1016/J.Neuroscience.2006.08.028  0.777
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/J.Neuron.2006.07.025  0.822
2006 Staley JK, Krishnan-Sarin S, Cosgrove KP, Krantzler E, Frohlich E, Perry E, Dubin JA, Estok K, Brenner E, Baldwin RM, Tamagnan GD, Seibyl JP, Jatlow P, Picciotto MR, London ED, et al. Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8707-14. PMID 16928859 DOI: 10.1523/Jneurosci.0546-06.2006  0.405
2006 Zanetti L, de Kerchove D'Exaerde A, Zanardi A, Changeux JP, Picciotto MR, Zoli M. Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum. Psychopharmacology. 187: 181-8. PMID 16826402 DOI: 10.1007/s00213-006-0419-y  0.585
2006 Hawes JJ, Narasimhaiah R, Picciotto MR. Galanin and galanin-like peptide modulate neurite outgrowth via protein kinase C-mediated activation of extracellular signal-related kinase. The European Journal of Neuroscience. 23: 2937-46. PMID 16819983 DOI: 10.1111/j.1460-9568.2006.04828.x  0.786
2006 Steiner RC, Hsiung HM, Picciotto MR. Cocaine self-administration and locomotor sensitization are not altered in CART knockout mice. Behavioural Brain Research. 171: 56-62. PMID 16621045 DOI: 10.1016/j.bbr.2006.03.022  0.795
2006 Hawes JJ, Narasimhaiah R, Picciotto MR. Galanin attenuates cyclic AMP regulatory element-binding protein (CREB) phosphorylation induced by chronic morphine and naloxone challenge in Cath.a cells and primary striatal cultures. Journal of Neurochemistry. 96: 1160-8. PMID 16417577 DOI: 10.1111/j.1471-4159.2005.03613.x  0.795
2006 Brunzell DH, Chang JR, Schneider B, Olausson P, Taylor JR, Picciotto MR. beta2-Subunit-containing nicotinic acetylcholine receptors are involved in nicotine-induced increases in conditioned reinforcement but not progressive ratio responding for food in C57BL/6 mice. Psychopharmacology. 184: 328-38. PMID 16133126 DOI: 10.1007/s00213-005-0099-z  0.795
2006 Picciotto M. Role of Nicotinic Acetylcholine Receptors in Neurodegeneration or Neuroprotection During Aging Cns Drug Reviews. 6: 28-28. DOI: 10.1111/j.1527-3458.2000.tb00173.x  0.404
2005 Picciotto MR, Hawes JJ, Brunzell DH, Zachariou V. Galanin can attenuate opiate reinforcement and withdrawal. Neuropeptides. 39: 313-5. PMID 15944028 DOI: 10.1016/j.npep.2004.12.001  0.815
2005 Hawes JJ, Brunzell DH, Wynick D, Zachariou V, Picciotto MR. GalR1, but not GalR2 or GalR3, levels are regulated by galanin signaling in the locus coeruleus through a cyclic AMP-dependent mechanism. Journal of Neurochemistry. 93: 1168-76. PMID 15934937 DOI: 10.1111/J.1471-4159.2005.03105.X  0.802
2005 Rabenstein RL, Addy NA, Caldarone BJ, Asaka Y, Gruenbaum LM, Peters LL, Gilligan DM, Fitzsimonds RM, Picciotto MR. Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2138-45. PMID 15728854 DOI: 10.1523/JNEUROSCI.3530-04.2005  0.777
2005 Picciotto M, Fornaserio E, Addy N, Brunzell D. S43 INVOLVEMENT OF SIGNAL TRANSDUCTION CASCADES IN NICOTINE REINFORCEMENT Behavioural Pharmacology. 16: S14. DOI: 10.1097/00008877-200509001-00043  0.808
2004 Caldarone BJ, Harrist A, Cleary MA, Beech RD, King SL, Picciotto MR. High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biological Psychiatry. 56: 657-64. PMID 15522249 DOI: 10.1016/J.Biopsych.2004.08.010  0.837
2004 Hawes JJ, Picciotto MR. Characterization of GalR1, GalR2, and GalR3 immunoreactivity in catecholaminergic nuclei of the mouse brain. The Journal of Comparative Neurology. 479: 410-23. PMID 15514977 DOI: 10.1002/cne.20329  0.672
2004 Wehner JM, Keller JJ, Keller AB, Picciotto MR, Paylor R, Booker TK, Beaudet A, Heinemann SF, Balogh SA. Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning. Neuroscience. 129: 11-24. PMID 15489024 DOI: 10.1016/J.Neuroscience.2004.07.016  0.419
2004 Harrist A, Beech RD, King SL, Zanardi A, Cleary MA, Caldarone BJ, Eisch A, Zoli M, Picciotto MR. Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor. Synapse (New York, N.Y.). 54: 200-6. PMID 15472930 DOI: 10.1002/Syn.20081  0.813
2004 King SL, Caldarone BJ, Picciotto MR. Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration. Neuropharmacology. 47: 132-9. PMID 15464132 DOI: 10.1016/j.neuropharm.2004.06.024  0.812
2004 Beech RD, Cleary MA, Treloar HB, Eisch AJ, Harrist AV, Zhong W, Greer CA, Duman RS, Picciotto MR. Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons. The Journal of Comparative Neurology. 475: 128-41. PMID 15176089 DOI: 10.1002/Cne.20179  0.709
2004 Stedman DR, Uboha NV, Stedman TT, Nairn AC, Picciotto MR. Cytoplasmic localization of calcium/calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain. Febs Letters. 566: 275-80. PMID 15147908 DOI: 10.1016/J.Febslet.2004.04.042  0.771
2003 Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Labarca C, Lester HA, Picciotto MR, Wehner JM, Collins AC. Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response. Alcoholism, Clinical and Experimental Research. 27: 1867-75. PMID 14691373 DOI: 10.1097/01.Alc.0000102700.72447.0F  0.669
2003 Stevens TR, Krueger SR, Fitzsimonds RM, Picciotto MR. Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10093-9. PMID 14602824 DOI: 10.1523/Jneurosci.23-31-10093.2003  0.812
2003 Picciotto MR. Nicotine as a modulator of behavior: beyond the inverted U. Trends in Pharmacological Sciences. 24: 493-9. PMID 12967775 DOI: 10.1016/S0165-6147(03)00230-X  0.46
2003 Caldarone BJ, Karthigeyan K, Harrist A, Hunsberger JG, Wittmack E, King SL, Jatlow P, Picciotto MR. Sex differences in response to oral amitriptyline in three animal models of depression in C57BL/6J mice. Psychopharmacology. 170: 94-101. PMID 12879206 DOI: 10.1007/S00213-003-1518-7  0.767
2003 Zachariou V, Brunzell DH, Hawes J, Stedman DR, Bartfai T, Steiner RA, Wynick D, Langel U, Picciotto MR. The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 100: 9028-33. PMID 12853567 DOI: 10.1073/Pnas.1533224100  0.813
2003 King SL, Marks MJ, Grady SR, Caldarone BJ, Koren AO, Mukhin AG, Collins AC, Picciotto MR. Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3837-43. PMID 12736354 DOI: 10.1523/Jneurosci.23-09-03837.2003  0.843
2003 Brunzell DH, Russell DS, Picciotto MR. In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice. Journal of Neurochemistry. 84: 1431-41. PMID 12614343 DOI: 10.1046/j.1471-4159.2003.01640.x  0.758
2003 Lambe EK, Picciotto MR, Aghajanian GK. Nicotine induces glutamate release from thalamocortical terminals in prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 216-25. PMID 12589374 DOI: 10.1038/sj.npp.1300032  0.45
2002 Picciotto MR, Zoli M. Nicotinic receptors in aging and dementia. Journal of Neurobiology. 53: 641-55. PMID 12436427 DOI: 10.1002/neu.10102  0.416
2002 Picciotto MR, Brunzell DH, Caldarone BJ. Effect of nicotine and nicotinic receptors on anxiety and depression. Neuroreport. 13: 1097-106. PMID 12151749 DOI: 10.1097/00001756-200207020-00006  0.825
2002 Ferrari R, Le Novère N, Picciotto MR, Changeux JP, Zoli M. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European Journal of Neuroscience. 15: 1810-8. PMID 12081661 DOI: 10.1046/j.1460-9568.2001.02009.x  0.55
2002 Marks MJ, Whiteaker P, Grady SR, Picciotto MR, McIntosh JM, Collins AC. Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice. Journal of Neurochemistry. 81: 1102-15. PMID 12065623 DOI: 10.1046/J.1471-4159.2002.00910.X  0.609
2002 Picciotto MR, Corrigall WA. Neuronal systems underlying behaviors related to nicotine addiction: neural circuits and molecular genetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3338-41. PMID 11978809 DOI: 10.1523/Jneurosci.22-09-03338.2002  0.481
2002 Zachariou V, Benoit-Marand M, Allen PB, Ingrassia P, Fienberg AA, Gonon F, Greengard P, Picciotto MR. Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1. Biological Psychiatry. 51: 612-20. PMID 11955461 DOI: 10.1016/S0006-3223(01)01318-X  0.693
2002 Di Paolo G, Sankaranarayanan S, Wenk MR, Daniell L, Perucco E, Caldarone BJ, Flavell R, Picciotto MR, Ryan TA, Cremona O, De Camilli P. Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron. 33: 789-804. PMID 11879655 DOI: 10.1016/S0896-6273(02)00601-3  0.747
2001 Picciotto MR, Caldarone BJ, Brunzell DH, Zachariou V, Stevens TR, King SL. Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacology & Therapeutics. 92: 89-108. PMID 11916531 DOI: 10.1016/S0163-7258(01)00161-9  0.837
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  0.799
2001 George TP, Picciotto MR, Verrico CD, Roth RH. Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects. Biological Psychiatry. 49: 300-6. PMID 11230881 DOI: 10.1016/S0006-3223(00)00928-8  0.403
2001 Grady SR, Meinerz NM, Cao J, Reynolds AM, Picciotto MR, Changeux JP, McIntosh JM, Marks MJ, Collins AC. Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry. 76: 258-68. PMID 11145999 DOI: 10.1046/j.1471-4159.2001.00019.x  0.637
2001 Zachariou V, Georgescu D, Kansal L, Merriam P, Picciotto MR. Galanin receptor 1 gene expression is regulated by cyclic AMP through a CREB-dependent mechanism. Journal of Neurochemistry. 76: 191-200. PMID 11145992 DOI: 10.1046/j.1471-4159.2001.00018.x  0.629
2000 Caldarone BJ, Duman CH, Picciotto MR. Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology. 39: 2779-84. PMID 11044747 DOI: 10.1016/S0028-3908(00)00137-4  0.711
2000 Marks MJ, Stitzel JA, Grady SR, Picciotto MR, Changeux JP, Collins AC. Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype. Neuropharmacology. 39: 2632-45. PMID 11044733 DOI: 10.1016/S0028-3908(00)00115-5  0.653
2000 George TP, Verrico CD, Picciotto MR, Roth RH. Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization. The Journal of Pharmacology and Experimental Therapeutics. 295: 58-66. PMID 10991961  0.355
2000 Caldarone BJ, George TP, Zachariou V, Picciotto MR. Gender differences in learned helplessness behavior are influenced by genetic background. Pharmacology, Biochemistry, and Behavior. 66: 811-7. PMID 10973520 DOI: 10.1016/S0091-3057(00)00271-9  0.744
2000 Paul S, Snyder GL, Yokakura H, Picciotto MR, Nairn AC, Lombroso PJ. The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5630-8. PMID 10908600 DOI: 10.1523/Jneurosci.20-15-05630.2000  0.7
2000 Wickman K, Karschin C, Karschin A, Picciotto MR, Clapham DE. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5608-15. PMID 10908597 DOI: 10.1523/Jneurosci.20-15-05608.2000  0.341
2000 Zachariou V, Thome J, Parikh K, Picciotto MR. Upregulation of galanin binding sites and GalR1 mRNA levels in the mouse locus coeruleus following chronic morphine treatments and precipitated morphine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 127-37. PMID 10882839 DOI: 10.1016/S0893-133X(00)00094-4  0.637
2000 Whiteaker P, Marks MJ, Grady SR, Lu Y, Picciotto MR, Changeux JP, Collins AC. Pharmacological and null mutation approaches reveal nicotinic receptor diversity. European Journal of Pharmacology. 393: 123-35. PMID 10771005 DOI: 10.1016/S0014-2999(00)00052-2  0.667
2000 Picciotto MR, Caldarone BJ, King SL, Zachariou V. Nicotinic receptors in the brain. Links between molecular biology and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 451-65. PMID 10731620 DOI: 10.1016/S0893-133X(99)00146-3  0.833
2000 Mukhin AG, Gündisch D, Horti AG, Koren AO, Tamagnan G, Kimes AS, Chambers J, Vaupel DB, King SL, Picciotto MR, Innis RB, London ED. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Molecular Pharmacology. 57: 642-9. PMID 10692507 DOI: 10.1124/MOL.57.3.642  0.689
2000 King SL, Picciotto MR. Mouse genetics and transgenics: a practical approach Heredity. 84: 733-734. DOI: 10.1046/j.1365-2540.2000.0728b.x  0.609
1999 Picciotto MR, Zoli M, Changeux JP. Use of knock-out mice to determine the molecular basis for the actions of nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 1: S121-5; discussion S. PMID 11768168 DOI: 10.1080/14622299050011931  0.621
1999 Epping-Jordan MP, Picciotto MR, Changeux JP, Pich EM. Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice. Psychopharmacology. 147: 25-6. PMID 10591862 DOI: 10.1007/s002130051135  0.59
1999 le Novère N, Zoli M, Léna C, Ferrari R, Picciotto MR, Merlo-Pich E, Changeux JP. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neuroreport. 10: 2497-501. PMID 10574359  0.505
1999 Lawson ND, Zain M, Zibello T, Picciotto MR, Nairn AC, Berliner N. Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation. Experimental Hematology. 27: 1682-90. PMID 10560916 DOI: 10.1016/S0301-472X(99)00108-3  0.591
1999 Picciotto MR. Knock-out mouse models used to study neurobiological systems. Critical Reviews in Neurobiology. 13: 103-49. PMID 10512487 DOI: 10.1615/Critrevneurobiol.V13.I2.10  0.343
1999 Kelz MB, Chen J, Carlezon WA, Whisler K, Gilden L, Beckmann AM, Steffen C, Zhang YJ, Marotti L, Self DW, Tkatch T, Baranauskas G, Surmeier DJ, Neve RL, Duman RS, ... Picciotto MR, et al. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature. 401: 272-6. PMID 10499584 DOI: 10.1038/45790  0.598
1999 Zachariou V, Parikh K, Picciotto MR. Centrally administered galanin blocks morphine place preference in the mouse. Brain Research. 831: 33-42. PMID 10411981 DOI: 10.1016/S0006-8993(99)01476-6  0.618
1999 Marks MJ, Whiteaker P, Calcaterra J, Stitzel JA, Bullock AE, Grady SR, Picciotto MR, Changeux JP, Collins AC. Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit. The Journal of Pharmacology and Experimental Therapeutics. 289: 1090-103. PMID 10215692  0.627
1999 Salmon AM, Damaj I, Sekine S, Picciotto MR, Marubio L, Changeux JP. Modulation of morphine analgesia in alphaCGRP mutant mice. Neuroreport. 10: 849-54. PMID 10208559 DOI: 10.1097/00001756-199903170-00033  0.484
1999 Zoli M, Picciotto MR, Ferrari R, Cocchi D, Changeux JP. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. The Embo Journal. 18: 1235-44. PMID 10064590 DOI: 10.1093/emboj/18.5.1235  0.559
1999 Picciotto MR. Use of animal models to test the specificity of nicotinic drugs Cns Drug Reviews. 5: 3. DOI: 10.1111/J.1527-3458.1999.Tb00117.X  0.348
1998 Picciotto MR, Wickman K. Using knockout and transgenic mice to study neurophysiology and behavior. Physiological Reviews. 78: 1131-63. PMID 9790572 DOI: 10.1152/Physrev.1998.78.4.1131  0.326
1998 Chen J, Kelz MB, Zeng G, Sakai N, Steffen C, Shockett PE, Picciotto MR, Duman RS, Nestler EJ. Transgenic animals with inducible, targeted gene expression in brain. Molecular Pharmacology. 54: 495-503. PMID 9730908 DOI: 10.1124/Mol.54.3.495  0.594
1998 Picciotto MR. Common aspects of the action of nicotine and other drugs of abuse. Drug and Alcohol Dependence. 51: 165-72. PMID 9716938 DOI: 10.1016/S0376-8716(98)00074-X  0.37
1998 Changeux JP, Bertrand D, Corringer PJ, Dehaene S, Edelstein S, Léna C, Le Novère N, Marubio L, Picciotto M, Zoli M. Brain nicotinic receptors: structure and regulation, role in learning and reinforcement. Brain Research. Brain Research Reviews. 26: 198-216. PMID 9651527 DOI: 10.1016/S0165-0173(97)00040-4  0.631
1998 Zoli M, Léna C, Picciotto MR, Changeux JP. Identification of four classes of brain nicotinic receptors using beta2 mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4461-72. PMID 9614223  0.522
1998 Picciotto MR, Zoli M, Rimondini R, Léna C, Marubio LM, Pich EM, Fuxe K, Changeux JP. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 391: 173-7. PMID 9428762 DOI: 10.1038/34413  0.62
1998 Zoli M, Léna C, Picciotto MR, Changeux J. Identification of Four Classes of Brain Nicotinic Receptors Using β2 Mutant Mice The Journal of Neuroscience. 18: 4461-4472. DOI: 10.1523/Jneurosci.18-12-04461.1998  0.776
1998 Picciotto MR. Nicotine addiction: From molecules to behavior Neuroscientist. 4: 391-394. DOI: 10.1177/107385849800400610  0.465
1998 Salmon A, Sekine S, Picciotto M, Damaj I, Changeux J. Analysis of developmental evolution of synapses in CGRP knock-out mice Journal of Physiology-Paris. 92: 488. DOI: 10.1016/S0928-4257(99)80104-1  0.301
1997 Picciotto MR, Zoli M, Zachariou V, Changeux JP. Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine. Biochemical Society Transactions. 25: 824-9. PMID 9388554 DOI: 10.1042/Bst0250824  0.735
1997 PICCIOTTO MR. NICOTINIC RECEPTOR β2 KNOCKOUT Biochemical Society Transactions. 25: 535S-535S. DOI: 10.1042/bst025535sb  0.379
1996 Picciotto MR, Nastiuk KL, Nairn AC. Structure, regulation, and function of calcium/calmodulin-dependent protein kinase I. Advances in Pharmacology (San Diego, Calif.). 36: 251-75. PMID 8783563 DOI: 10.1016/S1054-3589(08)60585-2  0.568
1996 Changeux J-, Bessis A, Bourgeois J-, Corringer P-, Devillers-Thiery A, Eiselé J-, Kerszberg M, Léna C, Novère NL, Picciotto M, Zoli M. Nicotinic Receptors And Brain Plasticity Cold Spring Harbor Symposia On Quantitative Biology. 61: 343-362. DOI: 10.1101/Sqb.1996.061.01.038  0.727
1996 Changeux J, Bessis A, Picciotto M, Zoli M. 35 Nicotinic receptors (nAChR) in the brain : Gene expression and contribution to learning and aging processes Neurobiology of Aging. 17: S9-S10. DOI: 10.1016/S0197-4580(96)80037-6  0.54
1995 Bessis A, Salmon AM, Zoli M, Le Novère N, Picciotto M, Changeux JP. Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice. Neuroscience. 69: 807-19. PMID 8596650 DOI: 10.1016/0306-4522(95)00303-Z  0.548
1995 Picciotto MR, Zoli M, Léna C, Bessis A, Lallemand Y, Le Novère N, Vincent P, Pich EM, Brûlet P, Changeux JP. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature. 374: 65-7. PMID 7870173 DOI: 10.1038/374065A0  0.615
1995 Picciotto MR, Zoli M, Bertuzzi G, Nairn AC. Immunochemical localization of calcium/calmodulin-dependent protein kinase I. Synapse (New York, N.Y.). 20: 75-84. PMID 7624832 DOI: 10.1002/syn.890200111  0.588
1995 Yokokura H, Picciotto MR, Nairn AC, Hidaka H. The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains. The Journal of Biological Chemistry. 270: 23851-9. PMID 7559563 DOI: 10.1074/jbc.270.40.23851  0.571
1994 Nairn AC, Picciotto MR. Calcium/calmodulin-dependent protein kinases. Seminars in Cancer Biology. 5: 295-303. PMID 7803766  0.524
1993 Picciotto MR, Czernik AJ, Nairn AC. Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site. The Journal of Biological Chemistry. 268: 26512-21. PMID 8253780  0.533
1993 Cohn JA, Strong TV, Picciotto MR, Nairn AC, Collins FS, Fitz JG. Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells. Gastroenterology. 105: 1857-64. PMID 7504645 DOI: 10.1016/0016-5085(93)91085-V  0.538
1992 Picciotto MR, Cohn JA, Bertuzzi G, Greengard P, Nairn AC. Phosphorylation of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 267: 12742-52. PMID 1377674  0.522
1988 Weeks G, Picciotto M, Nairn AC, Walaas SI, Greengard P. Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000. Synapse (New York, N.Y.). 2: 89-96. PMID 2844000 DOI: 10.1002/syn.890020112  0.73
1985 Schaefer M, Picciotto MR, Kreiner T, Kaldany RR, Taussig R, Scheller RH. Aplysia neurons express a gene encoding multiple FMRFamide neuropeptides. Cell. 41: 457-67. PMID 3838698 DOI: 10.1016/S0092-8674(85)80019-2  0.492
1984 Taussig R, Picciotto MR, Scheller RH. Two introns define functional domains of a neuropeptide precursor in Aplysia. Clinical and Experimental Hypertension. Part a, Theory and Practice. 6: 2133-40. PMID 6532597 DOI: 10.3109/10641968409046142  0.477
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