| Year |
Citation |
Score |
| 2022 |
Grosse L, Chouinard S, Pâquet S, Verreault M, Trottier J, Bélanger A, Barbier O. Androgen Glucuronidation in Mice: When, Where, and How. Biology. 11. PMID 35336777 DOI: 10.3390/biology11030403 |
0.586 |
|
| 2020 |
Kilanczyk E, Banales JM, Wunsch E, Barbier O, Avila MA, Mato JM, Milkiewicz M, Milkiewicz P. S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165895. PMID 32681864 DOI: 10.1016/J.Bbadis.2020.165895 |
0.326 |
|
| 2020 |
Hansmann E, Mennillo E, Yoda E, Verreault M, Barbier O, Chen SJ, Tukey RH. Differential role of LXRα and LXRβ in the regulation of UDP-glucuronosyltransferase 1A1 in humanized UGT1 mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31980500 DOI: 10.1124/Dmd.119.090068 |
0.383 |
|
| 2019 |
Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, ... ... Barbier O, et al. The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis. Jci Insight. 4. PMID 31391339 DOI: 10.1172/Jci.Insight.129492 |
0.324 |
|
| 2019 |
Thérien A, Verreault M, Trottier J, Vohl M, Barbier O. Mo1472 – Omega-3 Polyunsaturated Fatty Acids Improve Responses to Obeticholic Acid in Human Cell Models Gastroenterology. 156: S-1318-S-1319. DOI: 10.1016/S0016-5085(19)40313-2 |
0.321 |
|
| 2018 |
Wunsch E, Raszeja-Wyszomirska J, Barbier O, Milkiewicz M, Krawczyk M, Milkiewicz P. Effect of S-adenosyl-L-methionine on liver biochemistry and quality of life in patients with primary biliary cholangitis treated with ursodeoxycholic acid. A prospective, open label pilot study. Journal of Gastrointestinal and Liver Diseases : Jgld. 27: 273-279. PMID 30240471 DOI: 10.15403/Jgld.2014.1121.273.Icz |
0.304 |
|
| 2018 |
Perreault M, Wunsch E, Białek A, Trottier J, Verreault M, Caron P, Poirier GG, Milkiewicz P, Barbier O. Urinary Elimination of Bile Acid Glucuronides under Severe Cholestatic Situations: Contribution of Hepatic and Renal Glucuronidation Reactions. Canadian Journal of Gastroenterology & Hepatology. 2018: 8096314. PMID 29850459 DOI: 10.1155/2018/8096314 |
0.399 |
|
| 2018 |
Cieślak A, Trottier J, Verreault M, Milkiewicz P, Vohl MC, Barbier O. N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models. Canadian Journal of Gastroenterology & Hepatology. 2018: 6031074. PMID 29850457 DOI: 10.1155/2018/6031074 |
0.4 |
|
| 2017 |
Lu W, Rettenmeier E, Paszek M, Yueh MF, Tukey RH, Trottier J, Barbier O, Chen S. Crypt organoids culture as an in vitro model in drug metabolism and cytotoxicity studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28468837 DOI: 10.1124/Dmd.117.075945 |
0.323 |
|
| 2017 |
Allam-Ndoul B, Guénard F, Barbier O, Vohl MC. A Study of the Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Gene Expression Profiles of Stimulated Thp-1 Macrophages. Nutrients. 9. PMID 28441337 DOI: 10.3390/Nu9050424 |
0.338 |
|
| 2017 |
Song Y, Liu C, Liu X, Trottier J, Beaudoin M, Zhang L, Pope C, Peng G, Barbier O, Zhong X, Li L, Wang L. H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of EpCAM. Hepatology (Baltimore, Md.). PMID 28407375 DOI: 10.1002/Hep.29209 |
0.327 |
|
| 2017 |
Da Silva MS, Bigo C, Barbier O, Rudkowska I. Whey protein hydrolysate and branched-chain amino acids downregulate inflammation-related genes in vascular endothelial cells. Nutrition Research (New York, N.Y.). 38: 43-51. PMID 28381353 DOI: 10.1016/J.Nutres.2017.01.005 |
0.336 |
|
| 2017 |
Da Silva MS, Julien P, Bilodeau JF, Barbier O, Rudkowska I. Trans Fatty Acids Suppress TNF-α-Induced Inflammatory Gene Expression in Endothelial (HUVEC) and Hepatocellular Carcinoma (HepG2) Cells. Lipids. PMID 28315997 DOI: 10.1007/S11745-017-4243-4 |
0.385 |
|
| 2016 |
Dong X, Li H, Xie N, Chen R, Verreault M, Fazli L, Gleave ME, Barbier O. UGT2B17 expedites progression of castration-resistant prostate cancers by promoting ligand-independent AR signaling. Cancer Research. PMID 27659047 DOI: 10.1158/0008-5472.Can-16-1518 |
0.4 |
|
| 2016 |
Cieślak A, Kelly I, Trottier J, Verreault M, Wunsch E, Milkiewicz P, Poirier G, Droit A, Barbier O. Selective and sensitive quantification of the cytochrome P450 3A4 protein in human liver homogenates through multiple reaction monitoring mass spectrometry. Proteomics. PMID 27634100 DOI: 10.1002/Pmic.201500386 |
0.369 |
|
| 2016 |
Wunsch E, Krawczyk M, Milkiewicz M, Trottier J, Barbier O, Neurath MF, Lammert F, Kremer AE, Milkiewicz P. Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases. Scientific Reports. 6: 30847. PMID 27506882 DOI: 10.1038/Srep30847 |
0.307 |
|
| 2016 |
Allam-Ndoul B, Guénard F, Barbier O, Vohl MC. Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages. Lipids in Health and Disease. 15: 69. PMID 27044314 DOI: 10.1186/S12944-016-0241-4 |
0.336 |
|
| 2016 |
Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, Delker D, Zou A, Hagedorn CH, Wang L. Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function. Scientific Reports. 6: 20559. PMID 26838806 DOI: 10.1038/Srep20559 |
0.374 |
|
| 2016 |
Braadland PR, Grytli HH, Ramberg H, Katz B, Gauthier-Landry L, Kellmann R, Krobert KA, Wang W, Svindland A, Levy FO, Berge V, Mellgren G, Barbier O, Taskén KA. Abstract A01: ADRB2 regulates phase II steroid metabolism and determines development of castration-resistant prostate cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A01 |
0.442 |
|
| 2015 |
Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, ... ... Barbier O, et al. Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism. Oncotarget. PMID 26646591 DOI: 10.18632/Oncotarget.6479 |
0.388 |
|
| 2015 |
Wunsch E, Klak M, Wasik U, Milkiewicz M, Blatkiewicz M, Urasinska E, Barbier O, Bielicki D, Bogdanos DP, Elias E, Milkiewicz P. Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR. Journal of Immunology Research. 2015: 571353. PMID 26504856 DOI: 10.1155/2015/571353 |
0.332 |
|
| 2015 |
Wunsch E, Milkiewicz M, Wasik U, Trottier J, Kempińska-Podhorodecka A, Elias E, Barbier O, Milkiewicz P. Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease. Scientific Reports. 5: 13462. PMID 26293907 DOI: 10.1038/Srep13462 |
0.373 |
|
| 2015 |
Gauthier-Landry L, Bélanger A, Barbier O. Multiple roles for UDP-glucuronosyltransferase (UGT)2B15 and UGT2B17 enzymes in androgen metabolism and prostate cancer evolution. The Journal of Steroid Biochemistry and Molecular Biology. 145: 187-92. PMID 24861263 DOI: 10.1016/J.Jsbmb.2014.05.009 |
0.6 |
|
| 2015 |
Wunsch E, Milkiewicz M, Trottier J, Kempinska-Podhorodecka A, Wasik U, Elias E, Barbier O, Milkiewicz P. P1195 : Characteristic changes in bile acids synthesis regulatory mechanisms in primary biliary cirrhosis. UDCA non-response is associated with higher expression of FGF19 Journal of Hepatology. 62: S803. DOI: 10.1016/S0168-8278(15)31391-X |
0.329 |
|
| 2015 |
White PJ, Mitchell PL, Schwab M, Trottier J, Kang JX, Barbier O, Marette A. Corrigendum to "Transgenic-3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins" [Metab Clin Exp 64 (2015) 666-676] Metabolism: Clinical and Experimental. DOI: 10.1016/J.Metabol.2015.04.007 |
0.301 |
|
| 2014 |
Bigo C, Kaeding J, El Husseini D, Rudkowska I, Verreault M, Vohl MC, Barbier O. PPARα: A Master Regulator of Bilirubin Homeostasis. Ppar Research. 2014: 747014. PMID 25147562 DOI: 10.1155/2014/747014 |
0.428 |
|
| 2014 |
Wunsch E, Trottier J, Milkiewicz M, Raszeja-Wyszomirska J, Hirschfield GM, Barbier O, Milkiewicz P. Prospective evaluation of ursodeoxycholic acid withdrawal in patients with primary sclerosing cholangitis. Hepatology (Baltimore, Md.). 60: 931-40. PMID 24519384 DOI: 10.1002/Hep.27074 |
0.324 |
|
| 2014 |
Rudkowska I, Julien P, Couture P, Lemieux S, Tchernof A, Barbier O, Vohl MC. Cardiometabolic risk factors are influenced by Stearoyl-CoA Desaturase (SCD) -1 gene polymorphisms and n-3 polyunsaturated fatty acid supplementation. Molecular Nutrition & Food Research. 58: 1079-86. PMID 24375980 DOI: 10.1002/Mnfr.201300426 |
0.316 |
|
| 2013 |
Perreault M, Białek A, Trottier J, Verreault M, Caron P, Milkiewicz P, Barbier O. Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction. Plos One. 8: e80994. PMID 24244729 DOI: 10.1371/Journal.Pone.0080994 |
0.333 |
|
| 2013 |
Chen S, Yueh MF, Bigo C, Barbier O, Wang K, Karin M, Nguyen N, Tukey RH. Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proceedings of the National Academy of Sciences of the United States of America. 110: 19143-8. PMID 24191041 DOI: 10.1073/Pnas.1319123110 |
0.338 |
|
| 2013 |
Grosse L, Pâquet S, Caron P, Fazli L, Rennie PS, Bélanger A, Barbier O. Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications. Cancer Research. 73: 6963-71. PMID 24121496 DOI: 10.1158/0008-5472.Can-13-1462 |
0.58 |
|
| 2013 |
Trottier J, Perreault M, Rudkowska I, Levy C, Dallaire-Theroux A, Verreault M, Caron P, Staels B, Vohl MC, Straka RJ, Barbier O. Profiling serum bile acid glucuronides in humans: gender divergences, genetic determinants, and response to fenofibrate. Clinical Pharmacology and Therapeutics. 94: 533-43. PMID 23756370 DOI: 10.1038/Clpt.2013.122 |
0.346 |
|
| 2013 |
Perreault M, Gauthier-Landry L, Trottier J, Verreault M, Caron P, Finel M, Barbier O. The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1616-20. PMID 23756265 DOI: 10.1124/Dmd.113.052613 |
0.362 |
|
| 2013 |
Grosse L, Campeau AS, Caron S, Morin FA, Meunier K, Trottier J, Caron P, Verreault M, Barbier O. Enantiomer selective glucuronidation of the non-steroidal pure anti-androgen bicalutamide by human liver and kidney: role of the human UDP-glucuronosyltransferase (UGT)1A9 enzyme. Basic & Clinical Pharmacology & Toxicology. 113: 92-102. PMID 23527766 DOI: 10.1111/Bcpt.12071 |
0.428 |
|
| 2013 |
Bigo C, Caron S, Dallaire-Théroux A, Barbier O. Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT. Drug Metabolism Reviews. 45: 34-47. PMID 23330540 DOI: 10.3109/03602532.2012.751992 |
0.334 |
|
| 2013 |
Wunsch E, Trottier J, Barbier O, Milkiewicz P. 961 EFFECT OF URSODEOXYCHOLIC ACID WITHDRAWAL IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS Journal of Hepatology. 58: S396. DOI: 10.1016/S0168-8278(13)60963-0 |
0.381 |
|
| 2012 |
Pâquet S, Fazli L, Grosse L, Verreault M, Têtu B, Rennie PS, Bélanger A, Barbier O. Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression. The Journal of Clinical Endocrinology and Metabolism. 97: E428-32. PMID 22170718 DOI: 10.1210/Jc.2011-2064 |
0.309 |
|
| 2012 |
Trottier J, Caron P, Straka R, Barbier O. 568 FENOFIBRATE INCREASES BILE ACID GLUCURONIDATION IN HUMANS: A TARGETED METABOLOMIC STUDY Journal of Hepatology. 56: S226. DOI: 10.1016/S0168-8278(12)60581-9 |
0.353 |
|
| 2011 |
Trottier J, Białek A, Caron P, Straka RJ, Milkiewicz P, Barbier O. Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. Plos One. 6: e22094. PMID 21760958 DOI: 10.1371/Journal.Pone.0022094 |
0.324 |
|
| 2011 |
Trottier J, Caron P, Straka RJ, Barbier O. Profile of serum bile acids in noncholestatic volunteers: gender-related differences in response to fenofibrate. Clinical Pharmacology and Therapeutics. 90: 279-86. PMID 21716269 DOI: 10.1038/Clpt.2011.124 |
0.346 |
|
| 2010 |
Giton F, Caron P, Bérubé R, Bélanger A, Barbier O, Fiet J. Plasma estrone sulfate assay in men: Comparison of radioimmunoassay, mass spectrometry coupled to gas chromatography (GC-MS), and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Clinica Chimica Acta; International Journal of Clinical Chemistry. 411: 1208-13. PMID 20427015 DOI: 10.1016/J.Cca.2010.04.022 |
0.511 |
|
| 2010 |
Lévesque E, Ménard V, Laverdière I, Bellemare J, Barbier O, Girard H, Guillemette C. Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation. Pharmacogenetics and Genomics. 20: 195-210. PMID 20139797 DOI: 10.1097/Fpc.0B013E328336Ef1C |
0.463 |
|
| 2010 |
Rudkowska I, Caron-Dorval D, Verreault M, Couture P, Deshaies Y, Barbier O, Vohl MC. PPARalpha L162V polymorphism alters the potential of n-3 fatty acids to increase lipoprotein lipase activity. Molecular Nutrition & Food Research. 54: 543-50. PMID 19937854 DOI: 10.1002/Mnfr.200900085 |
0.314 |
|
| 2010 |
Trottier J, El Husseini D, Perreault M, Pâquet S, Caron P, Bourassa S, Verreault M, Inaba TT, Poirier GG, Bélanger A, Guillemette C, Trauner M, Barbier O. The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver. The Journal of Biological Chemistry. 285: 1113-21. PMID 19889628 DOI: 10.1074/Jbc.M109.073908 |
0.475 |
|
| 2010 |
Verreault M, Kaeding J, Caron P, Trottier J, Grosse L, Houssin E, Pâquet S, Perreault M, Barbier O. Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential. Drug Metabolism Reviews. 42: 110-22. PMID 19831728 DOI: 10.3109/03602530903219220 |
0.458 |
|
| 2010 |
Trottier J, Bialek A, Caron P, Milkiewicz P, Barbier O. 991 INTERINDIVIDUAL VARIABILITY OF BILE ACID GLUCURONIDATION AND HEPATIC UDP-GLUCURONOSYLTRANSFERASE EXPRESSION IN RESPONSE TO RIFAMPICIN: IN VIVO AND IN VITRO EVIDENCES Journal of Hepatology. 52: S383. DOI: 10.1016/S0168-8278(10)60992-0 |
0.351 |
|
| 2009 |
Rudkowska I, Verreault M, Barbier O, Vohl MC. Differences in transcriptional activation by the two allelic (L162V Polymorphic) variants of PPARα after Omega-3 fatty acids treatment. Ppar Research. 2009: 369602. PMID 19266045 DOI: 10.1155/2009/369602 |
0.355 |
|
| 2009 |
Barbier O, Trottier J, Kaeding J, Caron P, Verreault M. Lipid-activated transcription factors control bile acid glucuronidation. Molecular and Cellular Biochemistry. 326: 3-8. PMID 19130183 DOI: 10.1007/S11010-008-0001-5 |
0.405 |
|
| 2008 |
Barbier O, Bélanger A. Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate. Best Practice & Research. Clinical Endocrinology & Metabolism. 22: 259-70. PMID 18471784 DOI: 10.1016/J.Beem.2008.01.001 |
0.656 |
|
| 2008 |
Chouinard S, Yueh MF, Tukey RH, Giton F, Fiet J, Pelletier G, Barbier O, Bélanger A. Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. The Journal of Steroid Biochemistry and Molecular Biology. 109: 247-53. PMID 18467088 DOI: 10.1016/J.Jsbmb.2008.03.016 |
0.64 |
|
| 2008 |
Kaeding J, Bélanger J, Caron P, Verreault M, Bélanger A, Barbier O. Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells. Molecular Cancer Therapeutics. 7: 380-90. PMID 18281521 DOI: 10.1158/1535-7163.Mct-07-0455 |
0.419 |
|
| 2008 |
Kaeding J, Bouchaert E, Bélanger J, Caron P, Chouinard S, Verreault M, Larouche O, Pelletier G, Staels B, Bélanger A, Barbier O. Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells. The Biochemical Journal. 410: 245-53. PMID 17988216 DOI: 10.1042/Bj20071136 |
0.46 |
|
| 2007 |
Chouinard S, Barbier O, Bélanger A. UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. The Journal of Biological Chemistry. 282: 33466-74. PMID 17848572 DOI: 10.1074/Jbc.M703370200 |
0.564 |
|
| 2007 |
Caillier B, Lépine J, Tojcic J, Ménard V, Perusse L, Bélanger A, Barbier O, Guillemette C. A pharmacogenomics study of the human estrogen glucuronosyltransferase UGT1A3. Pharmacogenetics and Genomics. 17: 481-95. PMID 17558304 DOI: 10.1097/Fpc.0B013E32806D87A4 |
0.585 |
|
| 2007 |
Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH. Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 419-27. PMID 17151188 DOI: 10.1124/Dmd.106.013243 |
0.487 |
|
| 2006 |
Trottier J, Verreault M, Grepper S, Monté D, Bélanger J, Kaeding J, Caron P, Inaba TT, Barbier O. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology (Baltimore, Md.). 44: 1158-70. PMID 17058234 DOI: 10.1002/hep.21362 |
0.361 |
|
| 2006 |
Chouinard S, Pelletier G, Bélanger A, Barbier O. Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. Endocrinology. 147: 5431-42. PMID 16887906 DOI: 10.1210/En.2006-0229 |
0.638 |
|
| 2006 |
Verreault M, Senekeo-Effenberger K, Trottier J, Bonzo JA, Bélanger J, Kaeding J, Staels B, Caron P, Tukey RH, Barbier O. The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice. Hepatology (Baltimore, Md.). 44: 368-78. PMID 16871576 DOI: 10.1002/Hep.21259 |
0.491 |
|
| 2006 |
Caron P, Trottier J, Verreault M, Bélanger J, Kaeding J, Barbier O. Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses. Molecular Pharmaceutics. 3: 293-302. PMID 16749861 DOI: 10.1021/Mp060021L |
0.306 |
|
| 2006 |
Trottier J, Milkiewicz P, Kaeding J, Verreault M, Barbier O. Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors. Molecular Pharmaceutics. 3: 212-22. PMID 16749854 DOI: 10.1021/Mp060020T |
0.359 |
|
| 2006 |
Chouinard S, Tessier M, Vernouillet G, Gauthier S, Labrie F, Barbier O, Bélanger A. Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue. Molecular Pharmacology. 69: 908-20. PMID 16339389 DOI: 10.1124/Mol.105.015891 |
0.375 |
|
| 2006 |
CAILLIER B, VILLENEUVE L, BARBIER O, GUILLEMETTE C. OV-A-3Genetic determinants of the hepatic expression of the phase II conjugating UGT1A3 enzyme Clinical Pharmacology & Therapeutics. 79: P35-P35. DOI: 10.1016/J.Clpt.2005.12.124 |
0.347 |
|
| 2005 |
Chen S, Beaton D, Nguyen N, Senekeo-Effenberger K, Brace-Sinnokrak E, Argikar U, Remmel RP, Trottier J, Barbier O, Ritter JK, Tukey RH. Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. The Journal of Biological Chemistry. 280: 37547-57. PMID 16155002 DOI: 10.1074/Jbc.M506683200 |
0.34 |
|
| 2005 |
Barbier O, Girard H, Inoue Y, Duez H, Villeneuve L, Kamiya A, Fruchart JC, Guillemette C, Gonzalez FJ, Staels B. Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha. Molecular Pharmacology. 67: 241-9. PMID 15470081 DOI: 10.1124/mol.104.003863 |
0.34 |
|
| 2004 |
Chouinard S, Pelletier G, Bélanger A, Barbier O. Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. Endocrine Research. 30: 717-25. PMID 15666817 DOI: 10.1081/Erc-200044014 |
0.646 |
|
| 2003 |
Bélanger A, Pelletier G, Labrie F, Barbier O, Chouinard S. Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans. Trends in Endocrinology and Metabolism: Tem. 14: 473-9. PMID 14643063 DOI: 10.1016/J.Tem.2003.10.005 |
0.59 |
|
| 2003 |
Barbier O, Bélanger A. The cynomolgus monkey (Macaca fascicularis) is the best animal model for the study of steroid glucuronidation. The Journal of Steroid Biochemistry and Molecular Biology. 85: 235-45. PMID 12943709 DOI: 10.1016/S0960-0760(03)00235-8 |
0.664 |
|
| 2003 |
Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, Staels B. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme. The Journal of Biological Chemistry. 278: 32852-60. PMID 12810707 DOI: 10.1074/jbc.M305361200 |
0.376 |
|
| 2003 |
Girard C, Barbier O, Veilleux G, El-Alfy M, Bélanger A. Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites. Endocrinology. 144: 2659-68. PMID 12746330 DOI: 10.1210/En.2002-0052 |
0.651 |
|
| 2002 |
Girard C, Barbier O, Turgeon D, Bélanger A. Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid, glucocorticoid, androgen and oestrogen hormones. The Biochemical Journal. 365: 213-22. PMID 12071853 DOI: 10.1042/Bj20011594 |
0.798 |
|
| 2001 |
Barbier O, Girard C, Berger L, El Alfy M, Bélanger A, Hum DW. The androgen-conjugating uridine diphosphoglucuronosyltransferase-2B enzymes are differentially expressed temporally and spatially in the monkey follicle throughout the menstrual cycle. Endocrinology. 142: 2499-507. PMID 11356699 DOI: 10.1210/Endo.142.6.8040 |
0.51 |
|
| 2001 |
Barbier O, Albert C, Martineau I, Vallée M, High K, Labrie F, Hum DW, Labrie C, Bélanger A. Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes. Molecular Pharmacology. 59: 636-45. PMID 11179460 DOI: 10.1124/Mol.59.3.636 |
0.752 |
|
| 2000 |
Albert C, Barbier O, Valle E M, Beaudry G, Be Langer A, Hum DW. Distribution of Uridine Diphosphate-Glucuronosyltransferase (UGT) Expression and Activity in Cynomolgus Monkey Tissues: Evidence for Differential Expression of Steroid-Conjugating UGT Enzymes in Steroid Target Tissues. Endocrinology. 141: 2472-2480. PMID 28201193 DOI: 10.1210/endo.141.7.7583 |
0.728 |
|
| 2000 |
Barbier O, Lapointe H, El Alfy M, Hum DW, Bélanger A. Cellular localization of uridine diphosphoglucuronosyltransferase 2B enzymes in the human prostate by in situ hybridization and immunohistochemistry. The Journal of Clinical Endocrinology and Metabolism. 85: 4819-26. PMID 11134149 DOI: 10.1210/Jcem.85.12.7019 |
0.627 |
|
| 2000 |
Barbier O, Girard C, Breton R, Bélanger A, Hum DW. N-glycosylation and residue 96 are involved in the functional properties of UDP-glucuronosyltransferase enzymes. Biochemistry. 39: 11540-52. PMID 10995221 DOI: 10.1021/Bi000779P |
0.608 |
|
| 2000 |
Albert C, Barbier O, Vallée M, Beaudry G, Bélanger A, Hum DW. Distribution of uridine diphosphate-glucuronosyltransferase (UGT) expression and activity in cynomolgus monkey tissues: evidence for differential expression of steroid-conjugating UGT enzymes in steroid target tissues. Endocrinology. 141: 2472-80. PMID 10875248 DOI: 10.1210/Endo.141.7.7583 |
0.745 |
|
| 2000 |
Barbier O, Turgeon D, Girard C, Green MD, Tephly TR, Hum DW, Bélanger A. 3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 28: 497-502. PMID 10772627 |
0.748 |
|
| 1999 |
Barbier O, Le Vesque E, Be Langer A, Hum DW. UGT2B23, a Novel Uridine Diphosphate-Glucuronosyltransferase Enzyme Expressed in Steroid Target Tissues That Conjugates Androgen and Estrogen Metabolites. Endocrinology. 140: 5538-5548. PMID 28204286 DOI: 10.1210/endo.140.12.7192 |
0.354 |
|
| 1999 |
Barbier O, Lévesque E, Bélanger A, Hum DW. UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites. Endocrinology. 140: 5538-48. PMID 10579317 DOI: 10.1210/Endo.140.12.7192 |
0.559 |
|
| 1999 |
Hum DW, Bélanger A, Lévesque E, Barbier O, Beaulieu M, Albert C, Vallée M, Guillemette C, Tchernof A, Turgeon D, Dubois S. Characterization of UDP-glucuronosyltransferases active on steroid hormones. The Journal of Steroid Biochemistry and Molecular Biology. 69: 413-23. PMID 10419020 DOI: 10.1016/S0960-0760(99)00061-8 |
0.785 |
|
| 1999 |
Bélanger G, Barbier O, Hum DW, Bélanger A. Molecular cloning, expression and characterization of a monkey steroid UDP-glucuronosyltransferase, UGT2B19, that conjugates testosterone. European Journal of Biochemistry / Febs. 260: 701-8. PMID 10102998 DOI: 10.1046/J.1432-1327.1999.00197.X |
0.646 |
|
| 1999 |
Barbier O, Bélanger A, Hum DW. Cloning and characterization of a simian UDP-glucuronosyltransferase enzyme UGT2B20, a novel C19 steroid-conjugating protein. The Biochemical Journal. 337: 567-74. PMID 9895303 |
0.48 |
|
| 1999 |
BARBIER O, BÉLANGER A, HUM DW. Cloning and characterization of a simian UDP-glucuronosyltransferase enzyme UGT2B20, a novel C19 steroid-conjugating protein Biochemical Journal. 337: 567. DOI: 10.1042/Bj3370567 |
0.694 |
|
| 1998 |
Beaulieu M, Lévesque E, Barbier O, Turgeon D, Bélanger G, Hum DW, Bélanger A. Isolation and characterization of a simian UDP-glucuronosyltransferase UGT2B18 active on 3-hydroxyandrogens. Journal of Molecular Biology. 275: 785-94. PMID 9480769 DOI: 10.1006/Jmbi.1997.1486 |
0.784 |
|
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