| Year |
Citation |
Score |
| 2024 |
Maharani R, Muhajir MI, Dirgantara JM, Hardianto A, Mayanti T, Harneti D, Farabi K, Hidayat AT, Supratman U, Siahaan T. Synthesis and anticancer evaluation of [d-Ala]-nocardiotide A. Rsc Advances. 14: 4097-4104. PMID 38292272 DOI: 10.1039/d4ra00025k |
0.315 |
|
| 2023 |
Yusuf-Makagiansar H, Yakovleva TV, Weldele M, Mahadik R, Siahaan TJ. Evaluation of LFA-1 Peptide-Methotrexate Conjugates in Modulating Endothelial Cell Inflammation and Cytokine Regulation. Medical Research Archives. 11. PMID 37063234 DOI: 10.18103/mra.v11i2.3534 |
0.376 |
|
| 2022 |
Stephanie F, Saragih M, Tambunan USF, Siahaan TJ. Structural Design and Synthesis of Novel Cyclic Peptide Inhibitors Targeting Transcription. Life (Basel, Switzerland). 12. PMID 36143370 DOI: 10.3390/life12091333 |
0.3 |
|
| 2020 |
Dening TJ, Siahaan TJ, Hageman MJ. Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides. Journal of Pharmaceutical Sciences. PMID 33359310 DOI: 10.1016/j.xphs.2020.12.018 |
0.378 |
|
| 2020 |
Norouzi M, Yathindranath V, Thliveris JA, Kopec BM, Siahaan TJ, Miller DW. Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles. Scientific Reports. 10: 11292. PMID 32647151 DOI: 10.1038/S41598-020-68017-Y |
0.351 |
|
| 2019 |
Kopec BM, Kiptoo P, Zhao L, Rosa-Molinar E, Siahaan TJ. Non-Invasive Brain Delivery and Efficacy of BDNF to Stimulate Neuroregeneration and Suppression of Disease Relapse in EAE Mice. Molecular Pharmaceutics. PMID 31846344 DOI: 10.1021/Acs.Molpharmaceut.9B00644 |
0.306 |
|
| 2019 |
Ulapane KR, Kopec BM, Siahaan TJ. Improving In Vivo Brain Delivery of Monoclonal Antibody Using Novel Cyclic Peptides. Pharmaceutics. 11. PMID 31683745 DOI: 10.3390/Pharmaceutics11110568 |
0.456 |
|
| 2019 |
Ulapane KR, Kopec BM, Siahaan TJ. Brain Delivery and Brain Deposition of Proteins with Various Sizes. Molecular Pharmaceutics. PMID 31664837 DOI: 10.1021/Acs.Molpharmaceut.9B00763 |
0.342 |
|
| 2019 |
Sajesh BV, On NH, Omar R, Alrushaid S, Kopec BM, Wang WG, Sun HD, Lillico R, Lakowski TM, Siahaan TJ, Davies NM, Puno PT, Vanan MI, Miller DW. Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors. Pharmaceutics. 11. PMID 31533285 DOI: 10.3390/Pharmaceutics11090481 |
0.408 |
|
| 2018 |
Gupta V, Bhavanasi S, Quadir M, Singh K, Ghosh G, Vasamreddy K, Ghosh A, Siahaan TJ, Banerjee S, Banerjee SK. Protein PEGylation for cancer therapy: bench to bedside. Journal of Cell Communication and Signaling. PMID 30499020 DOI: 10.1007/S12079-018-0492-0 |
0.313 |
|
| 2018 |
Moral MEG, Siahaan TJ. Conjugates of Cell Adhesion Peptides for Therapeutics and Diagnostics Against Cancer and Autoimmune Diseases. Current Topics in Medicinal Chemistry. PMID 29357802 DOI: 10.2174/1568026618666180118154514 |
0.477 |
|
| 2017 |
Ulapane KR, Kopec BM, Moral MEG, Siahaan TJ. Peptides and Drug Delivery. Advances in Experimental Medicine and Biology. 1030: 167-184. PMID 29081054 DOI: 10.1007/978-3-319-66095-0_8 |
0.475 |
|
| 2017 |
Ulapane KR, On N, Kiptoo P, Williams TD, Miller DW, Siahaan TJ. Improving Brain Delivery of Biomolecules via BBB Modulation in Mouse and Rat: Detection using MRI, NIRF, and Mass Spectrometry. Nanotheranostics. 1: 217-231. PMID 28890866 DOI: 10.7150/ntno.19158 |
0.313 |
|
| 2017 |
Kuehl C, Thati S, Sullivan B, Sestak J, Thompson M, Siahaan T, Berkland C. Pulmonary Administration of Soluble Antigen Arrays is Superior to Antigen in Treatment of Experimental Autoimmune Encephalomyelitis. Journal of Pharmaceutical Sciences. PMID 28625726 DOI: 10.1016/J.Xphs.2017.06.008 |
0.353 |
|
| 2017 |
White DR, Khedri Z, Kiptoo P, Siahaan TJ, Tolbert TJ. Synthesis of a Bifunctional Peptide Inhibitor-IgG1 Fc Fusion that Suppresses Experimental Autoimmune Encephalomyelitis. Bioconjugate Chemistry. PMID 28581731 DOI: 10.1021/Acs.Bioconjchem.7B00175 |
0.472 |
|
| 2017 |
On NH, Babu S, Omar R, Alrushaid S, Wang Y, Pu J, Sun H, Davies N, Siahaan T, Issaivanan M, Miller DW. EXTH-80. ENHANCED THERAPEUTIC RESPONSE IN MURINE MEDULLOBLASTOMA TUMOR MODEL USING ADENANTHIN AND TRANSIENT MODULATION OF THE BLOOD-BRAIN BARRIER WITH CADHERIN PEPTIDE Neuro-Oncology. 19: vi90-vi90. DOI: 10.1093/Neuonc/Nox168.370 |
0.372 |
|
| 2017 |
On N, Alrushaia S, Davies N, Babu S, Vanan M, Siahaan T, Miller D. Transient Modulation of Blood-brain Barrier with E-cadherin Peptide Improves Adenanthin Penetration into the Brain for the Treatment of Medulloblastoma Journal of Pharmacological and Toxicological Methods. 88: 174. DOI: 10.1016/J.Vascn.2017.09.023 |
0.348 |
|
| 2016 |
Alaofi A, On N, Kiptoo P, Williams TD, Miller DW, Siahaan TJ. Comparison of Linear and Cyclic His-Ala-Val Peptides in Modulating the Blood-Brain Barrier Permeability: Impact on Delivery of Molecules to the Brain. Journal of Pharmaceutical Sciences. 105: 797-807. PMID 26869430 DOI: 10.1016/S0022-3549(15)00188-4 |
0.447 |
|
| 2016 |
Alaofi A, Farokhi E, Prasasty VD, Anbanandam A, Kuczera K, Siahaan TJ. Probing the Interaction between cHAVc3 Peptide and the EC1 Domain of E-cadherin using NMR and Molecular Dynamics Simulations. Journal of Biomolecular Structure & Dynamics. 1-48. PMID 26728967 DOI: 10.1080/07391102.2015.1133321 |
0.453 |
|
| 2015 |
Tabanor K, Lee P, Kiptoo P, Choi IY, Sherry EB, Eagle CS, Williams TD, Siahaan TJ. Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC-MS/MS and Gd-DTPA Using Magnetic Resonance Imaging. Molecular Pharmaceutics. PMID 26705088 DOI: 10.1021/Acs.Molpharmaceut.5B00607 |
0.347 |
|
| 2015 |
Badawi AH, Kiptoo P, Siahaan TJ. Immune Tolerance Induction against Experimental Autoimmune Encephalomyelitis (EAE) Using A New PLP-B7AP Conjugate that Simultaneously Targets B7/CD28 Costimulatory Signal and TCR/MHC-II Signal. Journal of Multiple Sclerosis. 2. PMID 26140285 DOI: 10.4172/2376-0389.1000131 |
0.413 |
|
| 2015 |
Laksitorini MD, Kiptoo PK, On NH, Thliveris JA, Miller DW, Siahaan TJ. Modulation of intercellular junctions by cyclic-ADT peptides as a method to reversibly increase blood-brain barrier permeability. Journal of Pharmaceutical Sciences. 104: 1065-75. PMID 25640479 DOI: 10.1002/Jps.24309 |
0.373 |
|
| 2015 |
Thati S, Kuehl C, Hartwell B, Sestak J, Siahaan T, Forrest ML, Berkland C. Routes of administration and dose optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis. Journal of Pharmaceutical Sciences. 104: 714-21. PMID 25447242 DOI: 10.1002/Jps.24272 |
0.301 |
|
| 2015 |
Prasasty VD, Krause ME, Tambunan US, Anbanandam A, Laurence JS, Siahaan TJ. (1)H, (13)C and (15)N backbone assignment of the EC-1 domain of human E-cadherin. Biomolecular Nmr Assignments. 9: 31-5. PMID 24510398 DOI: 10.1007/S12104-013-9539-6 |
0.427 |
|
| 2014 |
Büyüktimkin B, Kiptoo P, Siahaan TJ. Bifunctional Peptide Inhibitors Suppress Interleukin-6 Proliferation and Ameliorates Murine Collagen-Induced Arthritis. Journal of Clinical & Cellular Immunology. 5. PMID 26251760 DOI: 10.4172/2155-9899.1000273 |
0.811 |
|
| 2014 |
Sestak JO, Sullivan BP, Thati S, Northrup L, Hartwell B, Antunez L, Forrest ML, Vines CM, Siahaan TJ, Berkland C. Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis. Molecular Therapy. Methods & Clinical Development. 1: 14008. PMID 26015953 DOI: 10.1038/Mtm.2014.8 |
0.41 |
|
| 2014 |
Northrup L, Sestak JO, Sullivan BP, Thati S, Hartwell BL, Siahaan TJ, Vines CM, Berkland C. Co-delivery of autoantigen and b7 pathway modulators suppresses experimental autoimmune encephalomyelitis. The Aaps Journal. 16: 1204-13. PMID 25297853 DOI: 10.1208/S12248-014-9671-Y |
0.425 |
|
| 2014 |
Sestak JO, Fakhari A, Badawi AH, Siahaan TJ, Berkland C. Structure, size, and solubility of antigen arrays determines efficacy in experimental autoimmune encephalomyelitis. The Aaps Journal. 16: 1185-93. PMID 25193268 DOI: 10.1208/S12248-014-9654-Z |
0.409 |
|
| 2014 |
On NH, Kiptoo P, Siahaan TJ, Miller DW. Modulation of blood-brain barrier permeability in mice using synthetic E-cadherin peptide. Molecular Pharmaceutics. 11: 974-81. PMID 24495091 DOI: 10.1021/Mp400624V |
0.451 |
|
| 2014 |
Chittasupho C, Sestak J, Shannon L, Siahaan TJ, Vines CM, Berkland C. Hyaluronic acid graft polymers displaying peptide antigen modulate dendritic cell response in vitro. Molecular Pharmaceutics. 11: 367-73. PMID 24283935 DOI: 10.1021/Mp4003909 |
0.389 |
|
| 2014 |
Prasasty VD, Tambunan USF, Siahaan TJ. Homology modeling and molecular dynamics studies of ec1 domain of VE-Cadherin to elucidate docking interaction with Cadherin-derived peptide Online Journal of Biological Sciences. 14: 155-162. DOI: 10.3844/Ojbsci.2014.155.162 |
0.405 |
|
| 2013 |
Badawi AH, Siahaan TJ. Suppression of MOG- and PLP-induced experimental autoimmune encephalomyelitis using a novel multivalent bifunctional peptide inhibitor. Journal of Neuroimmunology. 263: 20-7. PMID 23911075 DOI: 10.1016/J.Jneuroim.2013.07.009 |
0.452 |
|
| 2013 |
Sestak J, Mullins M, Northrup L, Thati S, Forrest ML, Siahaan TJ, Berkland C. Single-step grafting of aminooxy-peptides to hyaluronan: a simple approach to multifunctional therapeutics for experimental autoimmune encephalomyelitis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 334-40. PMID 23541930 DOI: 10.1016/J.Jconrel.2013.03.015 |
0.483 |
|
| 2013 |
Kiptoo P, Büyüktimkin B, Badawi AH, Stewart J, Ridwan R, Siahaan TJ. Controlling immune response and demyelination using highly potent bifunctional peptide inhibitors in the suppression of experimental autoimmune encephalomyelitis. Clinical and Experimental Immunology. 172: 23-36. PMID 23480182 DOI: 10.1111/Cei.12029 |
0.815 |
|
| 2013 |
Büyüktimkin B, Manikwar P, Kiptoo PK, Badawi AH, Stewart JM, Siahaan TJ. Vaccinelike and prophylactic treatments of EAE with novel I-domain antigen conjugates (IDAC): targeting multiple antigenic peptides to APC. Molecular Pharmaceutics. 10: 297-306. PMID 23148513 DOI: 10.1021/Mp300440X |
0.807 |
|
| 2013 |
Kiptoo P, Laksitorini MD, Siahaan TJ. Peptide Delivery Handbook of Biologically Active Peptides. 1702-1710. DOI: 10.1016/B978-0-12-385095-9.00233-5 |
0.358 |
|
| 2012 |
Badawi AH, Siahaan TJ. Immune modulating peptides for the treatment and suppression of multiple sclerosis. Clinical Immunology (Orlando, Fla.). 144: 127-38. PMID 22722227 DOI: 10.1016/J.Clim.2012.05.010 |
0.387 |
|
| 2012 |
Majumdar S, Anderson ME, Xu CR, Yakovleva TV, Gu LC, Malefyt TR, Siahaan TJ. Methotrexate (MTX)-cIBR conjugate for targeting MTX to leukocytes: conjugate stability and in vivo efficacy in suppressing rheumatoid arthritis. Journal of Pharmaceutical Sciences. 101: 3275-91. PMID 22539217 DOI: 10.1002/Jps.23164 |
0.688 |
|
| 2012 |
Trivedi M, Laurence JS, Williams TD, Middaugh CR, Siahaan TJ. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. International Journal of Pharmaceutics. 431: 16-25. PMID 22531851 DOI: 10.1016/J.Ijpharm.2012.03.051 |
0.74 |
|
| 2012 |
Büyüktimkin B, Wang Q, Kiptoo P, Stewart JM, Berkland C, Siahaan TJ. Vaccine-like controlled-release delivery of an immunomodulating peptide to treat experimental autoimmune encephalomyelitis. Molecular Pharmaceutics. 9: 979-85. PMID 22375937 DOI: 10.1021/Mp200614Q |
0.787 |
|
| 2012 |
Manikwar P, Büyüktimkin B, Kiptoo P, Badawi AH, Galeva NA, Williams TD, Siahaan TJ. I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression. Bioconjugate Chemistry. 23: 509-17. PMID 22369638 DOI: 10.1021/Bc200580J |
0.803 |
|
| 2012 |
Badawi AH, Kiptoo P, Wang WT, Choi IY, Lee P, Vines CM, Siahaan TJ. Suppression of EAE and prevention of blood-brain barrier breakdown after vaccination with novel bifunctional peptide inhibitor. Neuropharmacology. 62: 1874-81. PMID 22210333 DOI: 10.1016/J.Neuropharm.2011.12.013 |
0.368 |
|
| 2012 |
Manikwar P, Kiptoo P, Badawi AH, Büyüktimkin B, Siahaan TJ. Antigen-specific blocking of CD4-specific immunological synapse formation using BPI and current therapies for autoimmune diseases. Medicinal Research Reviews. 32: 727-64. PMID 21433035 DOI: 10.1002/Med.20243 |
0.789 |
|
| 2012 |
Wang B, Gangwar S, Pauletti G, Siahaan T, Borchardt RT. Synthesis of an esterase-sensitive cyclic prodrug of a model hexapeptide having enhanced membrane permeability and enzymatic stability using a 3-(2'-hydroxy-4',6'-dimethylphenyl)-3,3-dimethyl propionic Acid promoiety. Methods in Molecular Medicine. 23: 53-69. PMID 21380891 DOI: 10.1385/0-89603-517-4:53 |
0.762 |
|
| 2012 |
Gangwar S, Pauletti GM, Siahaan TJ, Stella VJ, Borchardt RT. Synthesis of an esterase-sensitive cyclic prodrug of a model hexapeptide having enhanced membrane permeability and enzymatic stability using an acyloxyalkoxy promoiety. Methods in Molecular Medicine. 23: 37-51. PMID 21380890 DOI: 10.1385/0-89603-517-4:37 |
0.761 |
|
| 2012 |
Majumdar S, Siahaan TJ. Peptide-mediated targeted drug delivery. Medicinal Research Reviews. 32: 637-58. PMID 20814957 DOI: 10.1002/Med.20225 |
0.619 |
|
| 2012 |
Phongpradist R, Chittasupho C, Intasai N, Siahaan TJ, Berkland CJ, Charoenkwan P, Anuchapreeda S, Ampasavate C. Biodegradable nanoparticles surface modification techniques with cIBR peptide targeting to LFA-1 expressing leukemic cells Journal of Nanotechnology in Engineering and Medicine. 3. DOI: 10.1115/1.4023896 |
0.387 |
|
| 2011 |
Manikwar P, Zimmerman T, Blanco FJ, Williams TD, Siahaan TJ. Rapid identification of fluorochrome modification sites in proteins by LC ESI-Q-TOF mass spectrometry. Bioconjugate Chemistry. 22: 1330-6. PMID 21612301 DOI: 10.1021/Bc100560C |
0.785 |
|
| 2011 |
Manikwar P, Tejo BA, Shinogle H, Moore DS, Zimmerman T, Blanco F, Siahaan TJ. Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes. Theranostics. 1: 277-89. PMID 21611107 DOI: 10.7150/Thno/V01P0277 |
0.761 |
|
| 2011 |
Khondee S, Baoum A, Siahaan TJ, Berkland C. Calcium condensed LABL-TAT complexes effectively target gene delivery to ICAM-1 expressing cells. Molecular Pharmaceutics. 8: 788-98. PMID 21473630 DOI: 10.1021/Mp100393J |
0.369 |
|
| 2011 |
Chittasupho C, Shannon L, Siahaan TJ, Vines CM, Berkland C. Nanoparticles targeting dendritic cell surface molecules effectively block T cell conjugation and shift response. Acs Nano. 5: 1693-702. PMID 21375342 DOI: 10.1021/Nn102159G |
0.374 |
|
| 2011 |
Kiptoo P, Sinaga E, Calcagno AM, Zhao H, Kobayashi N, Tambunan US, Siahaan TJ. Enhancement of drug absorption through the blood-brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides. Molecular Pharmaceutics. 8: 239-49. PMID 21128658 DOI: 10.1021/Mp100293M |
0.746 |
|
| 2011 |
Fakhari A, Baoum A, Siahaan TJ, Le KB, Berkland C. Controlling ligand surface density optimizes nanoparticle binding to ICAM-1. Journal of Pharmaceutical Sciences. 100: 1045-56. PMID 20922813 DOI: 10.1002/Jps.22342 |
0.323 |
|
| 2010 |
Phongpradist R, Chittasupho C, Okonogi S, Siahaan T, Anuchapreeda S, Ampasavate C, Berkland C. LFA-1 on leukemic cells as a target for therapy or drug delivery. Current Pharmaceutical Design. 16: 2321-30. PMID 20618153 DOI: 10.2174/138161210791920450 |
0.39 |
|
| 2010 |
Satyanarayanajois SD, Büyüktimkin B, Gokhale A, Ronald S, Siahaan TJ, Latendresse JR. A peptide from the beta-strand region of CD2 protein that inhibits cell adhesion and suppresses arthritis in a mouse model. Chemical Biology & Drug Design. 76: 234-44. PMID 20572813 DOI: 10.1111/J.1747-0285.2010.01001.X |
0.443 |
|
| 2010 |
Ridwan R, Kiptoo P, Kobayashi N, Weir S, Hughes M, Williams T, Soegianto R, Siahaan TJ. Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor: structure optimization and pharmacokinetics. The Journal of Pharmacology and Experimental Therapeutics. 332: 1136-45. PMID 20026673 DOI: 10.1124/Jpet.109.161109 |
0.457 |
|
| 2010 |
Chittasupho C, Manikwar P, Krise JP, Siahaan TJ, Berkland C. cIBR effectively targets nanoparticles to LFA-1 on acute lymphoblastic T cells. Molecular Pharmaceutics. 7: 146-55. PMID 19883077 DOI: 10.1021/Mp900185U |
0.766 |
|
| 2010 |
Zhao H, Kiptoo P, Williams TD, Siahaan TJ, Topp EM. Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 141: 145-52. PMID 19748537 DOI: 10.1016/J.Jconrel.2009.09.002 |
0.4 |
|
| 2010 |
Sinaga E, Jois SD, Avery M, Makagiansar I, Tambunan US, Siahaan TJ. MODULASI JUNCTION ANTAR SEL MENGGUNAKAN PEPTIDA KADHERIN UPAYA MENINGKATKAN PENGHANTARAN OBAT Makara of Science Series. 8. DOI: 10.7454/Mss.V8I1.394 |
0.455 |
|
| 2010 |
Gangwar S, Pauletti GM, Siahaan TJ, Stella VJ, Borchardt RT. ChemInform Abstract: Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymatic Stability Using an Acyloxyalkoxy Promoiety Cheminform. 31: no-no. DOI: 10.1002/chin.200032253 |
0.651 |
|
| 2010 |
Wang B, Gangwar S, Pauletti G, Siahaan T, Borchardt RT. ChemInform Abstract: Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymic Stability Using a 3-(2′-Hydroxy-4′,6′-dimethylphenyl)-3,3-Dimethylpropionic Acid Promoiety Cheminform. 31: no-no. DOI: 10.1002/chin.200032252 |
0.648 |
|
| 2010 |
BARRY CEI, BATES RB, BEAVERS WA, CAMOU FA, GORDON BI, HSU HF, MILLS NS, OGLE CA, SIAHAAN TJ, SUVANNACHUT K, TAYLOR SR, WHITE JJ, YAGER KM. ChemInform Abstract: Delocalized Carbanions in Synthesis Cheminform. 23: no-no. DOI: 10.1002/chin.199201332 |
0.643 |
|
| 2009 |
Zheng K, Laurence JS, Kuczera K, Verkhivker G, Middaugh CR, Siahaan TJ. Characterization of multiple stable conformers of the EC5 domain of E-cadherin and the interaction of EC5 with E-cadherin peptides. Chemical Biology & Drug Design. 73: 584-98. PMID 19635050 DOI: 10.1111/J.1747-0285.2009.00818.X |
0.588 |
|
| 2009 |
Trivedi MV, Laurence JS, Siahaan TJ. The role of thiols and disulfides on protein stability Current Protein and Peptide Science. 10: 614-625. PMID 19538140 DOI: 10.2174/138920309789630534 |
0.738 |
|
| 2009 |
Chittasupho C, Xie SX, Baoum A, Yakovleva T, Siahaan TJ, Berkland CJ. ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 37: 141-50. PMID 19429421 DOI: 10.1016/J.Ejps.2009.02.008 |
0.37 |
|
| 2009 |
Tejo BA, Siahaan TJ. Solution structure of a novel T-cell adhesion inhibitor derived from the fragment of ICAM-1 receptor: cyclo(1,8)-Cys-Pro-Arg-Gly-Gly-Ser-Val-Cys. Biopolymers. 91: 633-41. PMID 19330816 DOI: 10.1002/bip.21192 |
0.395 |
|
| 2009 |
Majumdar S, Tejo BA, Badawi AH, Moore D, Krise JP, Siahaan TJ. Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60. Molecular Pharmaceutics. 6: 396-406. PMID 19296614 DOI: 10.1021/Mp800120T |
0.616 |
|
| 2009 |
Trivedi M, Davis RA, Shabaik Y, Roy A, Verkhivker G, Laurence JS, Middaugh CR, Siahaan TJ. The role of covalent dimerization on the physical and chemical stability of the EC1 domain of human E-cadherin. Journal of Pharmaceutical Sciences. 98: 3562-74. PMID 19199298 DOI: 10.1002/Jps.21686 |
0.726 |
|
| 2009 |
Zheng K, Middaugh CR, Siahaan TJ. Evaluation of the physical stability of the EC5 domain of E-cadherin: Effects of pH, temperature, ionic strength, and disulfide bonds Journal of Pharmaceutical Sciences. 98: 63-73. PMID 18428798 DOI: 10.1002/Jps.21418 |
0.437 |
|
| 2008 |
Kobayashi N, Kiptoo P, Kobayashi H, Ridwan R, Brocke S, Siahaan TJ. Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor. Clinical Immunology (Orlando, Fla.). 129: 69-79. PMID 18676182 DOI: 10.1016/J.Clim.2008.06.002 |
0.408 |
|
| 2008 |
Iskandarsyah, Tejo BA, Tambunan US, Verkhivker G, Siahaan TJ. Structural modifications of ICAM-1 cyclic peptides to improve the activity to inhibit heterotypic adhesion of T cells. Chemical Biology & Drug Design. 72: 27-33. PMID 18554252 DOI: 10.1111/J.1747-0285.2008.00676.X |
0.522 |
|
| 2008 |
Zhang N, Chittasupho C, Duangrat C, Siahaan TJ, Berkland C. PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1. Bioconjugate Chemistry. 19: 145-52. PMID 17997512 DOI: 10.1021/Bc700227Z |
0.437 |
|
| 2007 |
Zimmerman T, Oyarzabal J, Sebastián ES, Majumdar S, Tejo BA, Siahaan TJ, Blanco FJ. ICAM-1 peptide inhibitors of T-cell adhesion bind to the allosteric site of LFA-1. An NMR characterization. Chemical Biology & Drug Design. 70: 347-53. PMID 17868072 DOI: 10.1111/J.1747-0285.2007.00566.X |
0.623 |
|
| 2007 |
Yusuf-Makagiansar H, Yakovleva TV, Tejo BA, Jones K, Hu Y, Verkhivker GM, Audus KL, Siahaan TJ. Sequence recognition of alpha-LFA-1-derived peptides by ICAM-1 cell receptors: inhibitors of T-cell adhesion. Chemical Biology & Drug Design. 70: 237-46. PMID 17718718 DOI: 10.1111/J.1747-0285.2007.00549.X |
0.486 |
|
| 2007 |
Murray JS, Oney S, Page JE, Kratochvil-Stava A, Hu Y, Makagiansar IT, Brown JC, Kobayashi N, Siahaan TJ. Suppression of type 1 diabetes in NOD mice by bifunctional peptide inhibitor: modulation of the immunological synapse formation. Chemical Biology & Drug Design. 70: 227-36. PMID 17718717 DOI: 10.1111/J.1747-0285.2007.00552.X |
0.416 |
|
| 2007 |
Majumdar S, Kobayashi N, Krise JP, Siahaan TJ. Mechanism of internalization of an ICAM-1-derived peptide by human leukemic cell line HL-60: influence of physicochemical properties on targeted drug delivery. Molecular Pharmaceutics. 4: 749-58. PMID 17680719 DOI: 10.1021/Mp0700458 |
0.556 |
|
| 2007 |
Kobayashi N, Kobayashi H, Gu L, Malefyt T, Siahaan TJ. Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 322: 879-86. PMID 17522343 DOI: 10.1124/Jpet.107.123257 |
0.505 |
|
| 2006 |
Anderson ME, Tejo BA, Yakovleva T, Siahaan TJ. Characterization of binding properties of ICAM-1 peptides to LFA-1: inhibitors of T-cell adhesion. Chemical Biology & Drug Design. 68: 20-8. PMID 16923022 DOI: 10.1111/J.1747-0285.2006.00407.X |
0.624 |
|
| 2006 |
Zheng K, Trivedi M, Siahaan TJ. Structure and function of the intercellular junctions: barrier of paracellular drug delivery. Current Pharmaceutical Design. 12: 2813-24. PMID 16918412 DOI: 10.2174/138161206777947722 |
0.785 |
|
| 2006 |
He HT, Gürsoy RN, Kupczyk-Subotkowska L, Tian J, Williams T, Siahaan TJ. Synthesis and chemical stability of a disulfide bond in a model cyclic pentapeptide: cyclo(1,4)-Cys-Gly-Phe-Cys-Gly-OH. Journal of Pharmaceutical Sciences. 95: 2222-34. PMID 16883561 DOI: 10.1002/Jps.20701 |
0.438 |
|
| 2006 |
Dunehoo AL, Anderson M, Majumdar S, Kobayashi N, Berkland C, Siahaan TJ. Cell adhesion molecules for targeted drug delivery. Journal of Pharmaceutical Sciences. 95: 1856-72. PMID 16850395 DOI: 10.1002/Jps.20676 |
0.707 |
|
| 2006 |
Liederer BM, Fuchs T, Vander Velde D, Siahaan TJ, Borchardt RT. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides. Journal of Medicinal Chemistry. 49: 1261-70. PMID 16480263 DOI: 10.1021/Jm050277F |
0.373 |
|
| 2006 |
Kobayashi N, Ikesue A, Majumdar S, Siahaan TJ. Inhibition of e-cadherin-mediated homotypic adhesion of Caco-2 cells: a novel evaluation assay for peptide activities in modulating cell-cell adhesion. The Journal of Pharmacology and Experimental Therapeutics. 317: 309-16. PMID 16371447 DOI: 10.1124/Jpet.105.097535 |
0.567 |
|
| 2005 |
Krogmeier SL, Reddy DS, Vander Velde D, Lushington GH, Siahaan TJ, Middaugh CR, Borchardt RT, Topp EM. Deamidation of model beta-turn cyclic peptides in the solid state. Journal of Pharmaceutical Sciences. 94: 2616-31. PMID 16258986 DOI: 10.1002/Jps.20468 |
0.412 |
|
| 2005 |
Calcagno AM, Fostel JM, Orchekowski RP, Alston JT, Mattes WB, Siahaan TJ, Ware JA. Modulation of cell adhesion molecules in various epithelial cell lines after treatment with PP2. Molecular Pharmaceutics. 2: 170-84. PMID 15934778 DOI: 10.1021/Mp0499003 |
0.662 |
|
| 2005 |
Huang M, Matthews K, Siahaan TJ, Kevil CG. Alpha L-integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G67-73. PMID 15319185 DOI: 10.1152/Ajpgi.00267.2004 |
0.339 |
|
| 2005 |
Calcagno AM, Siahaan TJ. Physiological, Biochemical, and Chemical Barriers to Oral Drug Delivery Drug Delivery: Principles and Applications. 15-27. DOI: 10.1002/0471475734.ch2 |
0.62 |
|
| 2004 |
Calcagno AM, Fostel JM, Reyner EL, Sinaga E, Alston JT, Mattes WB, Siahaan TJ, Ware JA. Effects of an E-cadherin-derived peptide on the gene expression of Caco-2 cells. Pharmaceutical Research. 21: 2085-94. PMID 15587932 DOI: 10.1023/B:Pham.0000048201.00143.72 |
0.725 |
|
| 2004 |
Jining L, Makagiansar I, Yusuf-Makagiansar H, Chow VT, Siahaan TJ, Jois SD. Design, structure and biological activity of beta-turn peptides of CD2 protein for inhibition of T-cell adhesion. European Journal of Biochemistry / Febs. 271: 2873-86. PMID 15233784 DOI: 10.1111/J.1432-1033.2004.04198.X |
0.362 |
|
| 2004 |
Stotz CE, Borchardt RT, Middaugh CR, Siahaan TJ, Vander Velde D, Topp EM. Secondary structure of a dynamic type I' β-hairpin peptide Journal of Peptide Research. 63: 371-382. PMID 15102055 DOI: 10.1111/J.1399-3011.2004.00129.X |
0.368 |
|
| 2004 |
Anderson ME, Yakovleva T, Hu Y, Siahaan TJ. Inhibition of ICAM-1/LFA-1-mediated heterotypic T-cell adhesion to epithelial cells: design of ICAM-1 cyclic peptides. Bioorganic & Medicinal Chemistry Letters. 14: 1399-402. PMID 15006370 DOI: 10.1016/J.Bmcl.2003.09.100 |
0.65 |
|
| 2004 |
Zheng K, Makagiansar IT, Wang M, Urbauer JL, Kuczera K, Siahaan TJ. Expression, purification, and structural study of the EC4 domain of E-cadherin. Protein Expression and Purification. 33: 72-9. PMID 14680964 DOI: 10.1016/J.Pep.2003.08.021 |
0.487 |
|
| 2003 |
Anderson ME, Siahaan TJ. Mechanism of binding and internalization of ICAM-1-derived cyclic peptides by LFA-1 on the surface of T cells: a potential method for targeted drug delivery. Pharmaceutical Research. 20: 1523-32. PMID 14620502 DOI: 10.1023/A:1026188212126 |
0.654 |
|
| 2003 |
Shuxing Z, Ying WS, Siahaan TJ, Jois SD. Solution structure of a peptide derived from the beta subunit of LFA-1. Peptides. 24: 827-35. PMID 12948834 DOI: 10.1016/S0196-9781(03)00170-0 |
0.43 |
|
| 2003 |
Anderson ME, Siahaan TJ. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors. Peptides. 24: 487-501. PMID 12732350 DOI: 10.1016/S0196-9781(03)00083-4 |
0.648 |
|
| 2003 |
Jois SDS, Siahaan TJ. A peptide derived from LFA-1 protein that modulates T-cell adhesion binds to soluble ICAM-1 protein Journal of Biomolecular Structure and Dynamics. 20: 635-644. PMID 12643766 DOI: 10.1080/07391102.2003.10506880 |
0.486 |
|
| 2003 |
Xu CR, He HT, Song X, Siahaan TJ. Synthesis and comparison of physicochemical, transport, and antithrombic properties of a cyclic prodrug and the parent RGD peptidomimetic Tetrahedron. 59: 2861-2869. DOI: 10.1016/S0040-4020(03)00333-8 |
0.317 |
|
| 2002 |
Makagiansar IT, Ikesue A, Nguyen PD, Urbauer JL, Urbauer RJ, Siahaan TJ. Localized production of human E-cadherin-derived first repeat in Escherichia coli. Protein Expression and Purification. 26: 449-54. PMID 12460769 DOI: 10.1016/S1046-5928(02)00553-3 |
0.321 |
|
| 2002 |
Song X, Xu CR, He HT, Siahaan TJ. Synthesis of a novel cyclic prodrug of RGD peptidomimetic to improve its cell membrane permeation. Bioorganic Chemistry. 30: 285-301. PMID 12392707 DOI: 10.1016/S0045-2068(02)00013-5 |
0.332 |
|
| 2002 |
Sinaga E, Jois SD, Avery M, Makagiansar IT, Tambunan US, Audus KL, Siahaan TJ. Increasing paracellular porosity by E-cadherin peptides: discovery of bulge and groove regions in the EC1-domain of E-cadherin. Pharmaceutical Research. 19: 1170-9. PMID 12240943 DOI: 10.1023/A:1019850226631 |
0.474 |
|
| 2002 |
Ouyang H, Tang F, Siahaan TJ, Borchardt RT. A modified coumarinic acid-based cyclic prodrug of an opioid peptide: its enzymatic and chemical stability and cell permeation characteristics. Pharmaceutical Research. 19: 794-801. PMID 12134949 DOI: 10.1023/A:1016148631055 |
0.435 |
|
| 2002 |
Makagiansar IT, Yusuf-Makagiansar H, Ikesue A, Calcagno AM, Murray JS, Siahaan TJ. N-cadherin involvement in the heterotypic adherence of malignant T-cells to epithelia. Molecular and Cellular Biochemistry. 233: 1-8. PMID 12083363 DOI: 10.1023/A:1015556625038 |
0.671 |
|
| 2002 |
Murray JS, Fois SD, Schountz T, Ford SR, Tawde MD, Brown JC, Siahaan TJ. Modeling alternative binding registers of a minimal immunogenic peptide on two class II major histocompatibility complex (MHC II) molecules predicts polarized T-cell receptor (TCR) contact positions. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 115-22. PMID 11985705 DOI: 10.1034/J.1399-3011.2002.01960.X |
0.467 |
|
| 2002 |
Ouyang H, Borchardt RT, Siahaan TJ, Vander Velde DG. Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion Journal of Peptide Research. 59: 183-195. PMID 11972752 DOI: 10.1034/J.1399-3011.2002.1O983.X |
0.353 |
|
| 2002 |
Xu CR, Yusuf-Makagiansar H, Hu Y, Jois SD, Siahaan TJ. Structural and ICAM-1-docking properties of a cyclic peptide from the I-domain of LFA-1: an inhibitor of ICAM-1/LFA- 1-mediated T-cell adhesion. Journal of Biomolecular Structure & Dynamics. 19: 789-99. PMID 11922836 DOI: 10.1080/07391102.2002.10506785 |
0.489 |
|
| 2002 |
Mahadevan J, Xu C, Siahaan T, Kuczera K. Molecular dynamics simulations of conformational behavior of linear RGD peptidomimetics and cyclic prodrugs in aqueous and octane solutions Journal of Biomolecular Structure and Dynamics. 19: 775-788. PMID 11922835 DOI: 10.1080/07391102.2002.10506784 |
0.305 |
|
| 2002 |
Yusuf-Makagiansar H, Anderson ME, Yakovleva TV, Murray JS, Siahaan TJ. Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases. Medicinal Research Reviews. 22: 146-67. PMID 11857637 DOI: 10.1002/Med.10001 |
0.621 |
|
| 2002 |
Makagiansar IT, Nguyen PD, Ikesue A, Kuczera K, Dentler W, Urbauer JL, Galeva N, Alterman M, Siahaan TJ. Disulfide bond formation promotes the cis- and trans-dimerization of the E-cadherin-derived first repeat. The Journal of Biological Chemistry. 277: 16002-10. PMID 11856755 DOI: 10.1074/Jbc.M200916200 |
0.306 |
|
| 2002 |
Hu Y, Webb E, Singh J, Morgan BA, Gainor JA, Gordon TD, Siahaan TJ. Rapid determination of substrate specificity of Clostridium histolyticum beta-collagenase using an immobilized peptide library. The Journal of Biological Chemistry. 277: 8366-71. PMID 11724807 DOI: 10.1074/Jbc.M111042200 |
0.334 |
|
| 2001 |
Yusuf-Makagiansar H, Makagiansar IT, Hu Y, Siahaan TJ. Synergistic inhibitory activity of alpha- and beta-LFA-1 peptides on LFA-1/ICAM-1 interaction Peptides. 22: 1955-1962. PMID 11786177 DOI: 10.1016/S0196-9781(01)00546-0 |
0.405 |
|
| 2001 |
Makagiansar IT, Avery M, Hu Y, Audus KL, Siahaan TJ. Improving the selectivity of HAV-peptides in modulating E-cadherin-E-cadherin interactions in the intercellular junction of MDCK cell monolayers Pharmaceutical Research. 18: 446-453. PMID 11451030 DOI: 10.1023/A:1011094025008 |
0.495 |
|
| 2001 |
Yusuf-Makagiansar H, Siahaan TJ. Binding and internalization of an LFA-1-derived cyclic peptide by ICAM receptors on activated lymphocyte: A potential ligand for drug targeting to ICAM-1-expressing cells Pharmaceutical Research. 18: 329-335. PMID 11442273 DOI: 10.1023/A:1011007014510 |
0.475 |
|
| 2001 |
Yusuf-Makagiansar H, Makagiansar IT, Siahaan TJ. Inhibition of the adherence of T-lymphocytes to epithelial cells by a cyclic peptide derived from inserted domain of lymphocyte function-associated antigen-1 Inflammation. 25: 203-214. PMID 11403212 DOI: 10.1023/A:1011044616170 |
0.454 |
|
| 2000 |
Tibbetts SA, Seetharama Jois D, Siahaan TJ, Benedict SH, Chan MA. Linear and cyclic LFA-1 and ICAM-1 peptides inhibit T cell adhesion and function. Peptides. 21: 1161-7. PMID 11035201 DOI: 10.1016/S0196-9781(00)00255-2 |
0.503 |
|
| 1999 |
Jois SDS, Hughes R, Siahaan TJ. Comparison of the solution conformations of a cell-adhesive peptide LBE and its reverse sequence EBL Journal of Biomolecular Structure and Dynamics. 17: 429-444. PMID 10636079 DOI: 10.1080/07391102.1999.10508375 |
0.49 |
|
| 1999 |
Tibbetts SA, Chirathaworn C, Nakashima M, Jois DS, Siahaan TJ, Chan MA, Benedict SH. Peptides derived from ICAM-1 and LFA-1 modulate T cell adhesion and immune function in a mixed lymphocyte culture. Transplantation. 68: 685-92. PMID 10507489 DOI: 10.1097/00007890-199909150-00015 |
0.383 |
|
| 1999 |
Bogdanowich-Knipp SJ, Jois SDS, Siahaan TJ. Effect of conformation on the conversion of cyclo-(1,7)-Gly-Arg-Gly- Asp-Ser-Pro-Asp-Gly-OH to its cyclic imide degradation product Journal of Peptide Research. 54: 43-53. PMID 10448969 DOI: 10.1034/J.1399-3011.1999.00091.X |
0.476 |
|
| 1999 |
Bogdanowich-Knipp SJ, Chakrabarti S, Williams TD, Dillman RK, Siahaan TJ. Solution stability of linear vs. cyclic RGD peptides Journal of Peptide Research. 53: 530-541. PMID 10424348 DOI: 10.1034/J.1399-3011.1999.00052.X |
0.47 |
|
| 1999 |
Bogdanowich-Knipp SJ, Jois DSS, Siahaan TJ. The effect of conformation on the solution stability of linear vs. cyclic RGD peptides Journal of Peptide Research. 53: 523-529. PMID 10424347 DOI: 10.1034/J.1399-3011.1999.00055.X |
0.479 |
|
| 1999 |
Gürsoy RN, Jois DSS, Siahaan TJ. Structural recognition of an ICAM-1 peptide by its receptor on the surface of T cells: Conformational studies of cyclo (1, 12)-Pen-Pro-Arg-Gly- Gly-Ser-Val-Leu-Val-Thr-Gly-Cys-OH Journal of Peptide Research. 53: 422-431. PMID 10406220 DOI: 10.1034/J.1399-3011.1999.00080.X |
0.483 |
|
| 1999 |
Gürsoy RN, Siahaan TJ. Binding and internalization of an ICAM-1 peptide by the surface receptors of T cells Journal of Peptide Research. 53: 414-421. PMID 10406219 DOI: 10.1034/J.1399-3011.1999.00079.X |
0.458 |
|
| 1999 |
Gudmundsson OS, Vander Velde DG, Jois SDS, Bak A, Siahaan TJ, Borchardt RT. The effect of conformation of the acyloxyalkoxy-based cyclic prodrugs of opioid peptides on their membrane permeability Journal of Peptide Research. 53: 403-413. PMID 10406218 DOI: 10.1034/J.1399-3011.1999.00077.X |
0.391 |
|
| 1999 |
Bak A, Siahaan TJ, Gudmundsson OS, Gangwar S, Friis GJ, Borchardt RT. Synthesis and evaluation of the physicochemical properties of esterase- sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker Journal of Peptide Research. 53: 393-402. PMID 10406217 DOI: 10.1034/J.1399-3011.1999.00070.X |
0.709 |
|
| 1999 |
Gudmundsson OS, Jois SDS, Vander Velde DG, Siahaan TJ, Wang B, Borchardt RT. The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides Journal of Peptide Research. 53: 383-392. PMID 10406216 DOI: 10.1034/J.1399-3011.1999.00076.X |
0.419 |
|
| 1999 |
Wang B, Nimkar K, Wang W, Zhang H, Shan D, Gudmundsson O, Gangwar S, Siahaan T, Borchardt RT. Synthesis and evaluation of the physicochemical properties of esterase- sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers Journal of Peptide Research. 53: 370-382. PMID 10406215 DOI: 10.1034/J.1399-3011.1999.00071.X |
0.732 |
|
| 1999 |
Jois SD, Tibbetts SA, Chan MA, Benedict SH, Siahaan TJ. A Ca2+ binding cyclic peptide derived from the alpha-subunit of LFA-1: inhibitor of ICAM-1/LFA-1-mediated T-cell adhesion. The Journal of Peptide Research : Official Journal of the American Peptide Society. 53: 18-29. PMID 10195438 DOI: 10.1111/J.1399-3011.1999.Tb01613.X |
0.474 |
|
| 1999 |
Bak A, Gudmundsson OS, Friis GJ, Siahaan TJ, Borchardt RT. Acyloxyalkoxy-based cyclic prodrugs of opioid peptides: Evaluation of the chemical and enzymatic stability as well as their transport properties across Caco-2 cell monolayers Pharmaceutical Research. 16: 24-29. PMID 9950274 DOI: 10.1023/A:1018854308829 |
0.4 |
|
| 1999 |
Gudmundsson OS, Nimkar K, Gangwar S, Siahaan T, Borchardt RT. Phenylpropionic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeation Pharmaceutical Research. 16: 16-23. PMID 9950273 DOI: 10.1023/A:1018802324759 |
0.725 |
|
| 1999 |
Jois SDS, Tibbetts SA, Chan MA, Benedict SH, Siahaan TJ. A Ca2+ binding cyclic peptide derived from the α-subunit of LFA-1: Inhibitor of ICAM-1/LFA-1-mediated T-cell adhesion Journal of Peptide Research. 53: 18-29. |
0.376 |
|
| 1997 |
T Borchardt R, Jeffrey Aubé, Siahaan TJ, Gangwar S, Pauletti GM. Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies. Advanced Drug Delivery Reviews. 27: 235-256. PMID 10837560 DOI: 10.1016/S0169-409X(97)00045-8 |
0.455 |
|
| 1997 |
Knipp GT, Vander Velde DG, Siahaan TJ, Borchardt RT. The effect of β-turn structure on the passive diffusion of peptides across caco-2 cell monolayers Pharmaceutical Research. 14: 1332-1340. PMID 9358544 DOI: 10.1023/A:1012152117703 |
0.471 |
|
| 1997 |
Lutz KL, Siahaan TJ. Molecular structure of the apical junction corn plex and its contribution to the paracellular barrier Journal of Pharmaceutical Sciences. 86: 977-984. PMID 9294808 DOI: 10.1021/Js970134J |
0.344 |
|
| 1997 |
Jois DS, Pal D, Tibbetts SA, Chan MA, Benedict SH, Siahaan TJ. Inhibition of homotypic adhesion of T-cells: secondary structure of an ICAM-1-derived cyclic peptide. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 517-26. PMID 9266479 DOI: 10.1111/J.1399-3011.1997.Tb01159.X |
0.506 |
|
| 1997 |
Hühmer AFR, Aced GI, Perkins MD, Gürsoy RN, Seetharama Jois DS, Larive C, Siahaan TJ, Schöneich C. Separation and analysis of peptides and proteins Analytical Chemistry. 69. PMID 9195854 |
0.326 |
|
| 1997 |
Jois DSS, Conrad MW, Chakrabarti S, Siahaan TJ. Conformational analysis of cyclo(2,9)-Ac-QCRSVEGSCG-OH from the C- terminal loop of human growth hormone Journal of Peptide Research. 49: 15-22. PMID 9128096 DOI: 10.1111/J.1399-3011.1997.Tb01116.X |
0.455 |
|
| 1997 |
Okumu FW, Pauletti GM, Vander Velde DG, Siahaan TJ, Borchardt RT. Effect of restricted conformational flexibility on the permeation of model hexapeptides across caco-2 cell monolayers Pharmaceutical Research. 14: 169-175. PMID 9090704 DOI: 10.1023/A:1012092409216 |
0.343 |
|
| 1997 |
Pal D, Audus KL, Siahaan TJ. Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide Brain Research. 747: 103-113. PMID 9042533 DOI: 10.1016/S0006-8993(96)01223-1 |
0.312 |
|
| 1997 |
Lutz KL, Siahaan TJ. Modulation of the cellular]unction protein E-cadherin in bovine brain microvessel endothelial cells by cadherin peptides Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 4: 187-193. DOI: 10.3109/10717549709051891 |
0.46 |
|
| 1997 |
Wang B, Gangwar S, Pauletti GM, Siahaan TJ, Borchardt RT. Synthesis of a novel esterase-sensitive cyclic prodrug system for peptides that utilizes a 'trimethyl lock'-facilitated lactonization reaction Journal of Organic Chemistry. 62: 1363-1367. DOI: 10.1021/Jo961778Z |
0.761 |
|
| 1997 |
Gangwar S, Pauletti GM, Siahaan TJ, Stella VJ, Borchardt RT. Synthesis of a novel esterase-sensitive cyclic prodrug of a hexapeptide using an (acyloxy)alkoxy promoiety Journal of Organic Chemistry. 62: 1356-1362. DOI: 10.1021/Jo961696A |
0.743 |
|
| 1997 |
Gangwar S, Pauletti GM, Wang B, Siahaan TJ, Stella VJ, Borchardt RT. Prodrug strategies to enhance the intestinal absorption of peptides Drug Discovery Today. 2: 148-155. DOI: 10.1016/S1359-6446(97)01011-8 |
0.754 |
|
| 1997 |
Pauletti GM, Gangwar S, Siahaan TJ, Aubé J, Borchardt RT. Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies Advanced Drug Delivery Reviews. 27: 235-256. DOI: 10.1016/S0169-409X(97)00045-8 |
0.348 |
|
| 1997 |
Gangwar S, Pauletti GM, Wang B, Siahaan TJ, Stella VJ, Borchardt RT. Novel esterase-sensitive cyclic prodrugs of a model hexapeptide having enhanced membrane permeability and enzymatic stability Pharmacochemistry Library. 28: 27-34. DOI: 10.1016/S0165-7208(97)80050-5 |
0.761 |
|
| 1996 |
Lutz KL, Szabo LA, Thompson DL, Siahaan TJ. Antibody recognition of peptide sequences from the cell-cell adhesion proteins: N- and E-cadherins Peptide Research. 9: 233-239. PMID 9000249 |
0.34 |
|
| 1996 |
Gangwar S, Jois SDS, Siahaan TJ, Vander Velde DG, Stella VJ, Borchardt RT. The effect of conformation on membrane permeability of an acyloxyalkoxy-linked cyclic prodrug of a model hexapeptide Pharmaceutical Research. 13: 1657-1662. PMID 8956330 DOI: 10.1023/A:1016484522113 |
0.685 |
|
| 1996 |
Pauletti GM, Gangwar S, Okumu FW, Siahaan TJ, Stella VJ, Borchardt RT. Esterase-sensitive cyclic prodrugs of peptides: Evaluation of an acyloxyalkoxy promoiety in a model hexapeptide Pharmaceutical Research. 13: 1615-1623. PMID 8956324 DOI: 10.1023/A:1016472119387 |
0.736 |
|
| 1996 |
Jois SDS, Tambunan USF, Chakrabarti S, Siahaan TJ. Solution structure of a cyclic RGD peptide that inhibits platelet aggregation Journal of Biomolecular Structure and Dynamics. 14: 1-12. PMID 8877556 DOI: 10.1080/07391102.1996.10508923 |
0.463 |
|
| 1996 |
Pauletti GM, Gangwar S, Knipp GT, Nerurkar MM, Okumu FW, Tamura K, Siahaan TJ, Borchardt RT. Structural requirements for intestinal absorption of peptide drugs Journal of Controlled Release. 41: 3-17. DOI: 10.1016/0168-3659(96)01352-1 |
0.749 |
|
| 1995 |
Lutz KL, Jois SDS, Siahaan TJ. Secondary structure of the hav peptide which regulates cadherin-cadherin interaction Journal of Biomolecular Structure and Dynamics. 13: 447. PMID 8825724 DOI: 10.1080/07391102.1995.10508854 |
0.447 |
|
| 1995 |
Oliyai R, Siahaan TJ, Stella VJ. The Importance of Structural Factors on the Rate and the Extent of N,O-acyl Migration in Cyclic and Linear Peptides Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 323-328. PMID 7617515 DOI: 10.1023/A:1016231913858 |
0.435 |
|
| 1995 |
Lutz KL, Siahaan TJ. E-cadherin peptide sequence recognition by anti-E-cadherin antibody Biochemical and Biophysical Research Communications. 211: 21-27. PMID 7540004 DOI: 10.1006/Bbrc.1995.1772 |
0.446 |
|
| 1994 |
Siahaan TJ, Lutz K. Conformational study of cyclo[Gln-Trp-Phe-Gly-Leu-Met] as NK-2 antagonist by NMR and molecular dynamics Journal of Pharmaceutical and Biomedical Analysis. 12: 65-71. PMID 8161607 DOI: 10.1016/0731-7085(94)80011-1 |
0.409 |
|
| 1994 |
Siahaan TJ, Bruss D, Powell NA, Chakrabarti S, Conrad M. The aqueous conformation of cyclo(1,6)Ac-Cys-Arg-Gly-Asp-Phe-Pen-NH2 International Journal of Peptide and Protein Research. 44: 427-434. PMID 7896500 DOI: 10.1111/J.1399-3011.1994.Tb00178.X |
0.457 |
|
| 1991 |
Barry III CE, Bates RB, Beavers WA, Camou FA, Gordon III B, Hsu HF, Mills NS, Ogle CA, Siahaan TJ, Suvannachut K, Taylor SR, White JJ, Yager KM. Delocalized Carbanions in Synthesis Synlett. 1991: 207-212. DOI: 10.1055/S-1991-20682 |
0.667 |
|
| 1990 |
Bates RB, Siahaan TJ, Suvannachut K. A new rearrangement of alkoxybenzyl anions Journal of Organic Chemistry. 55: 1328-1334. DOI: 10.1021/Jo00291A044 |
0.48 |
|
| 1990 |
Lipshutz BH, Huff BE, McCarthy KE, Mukarram SMJ, Siahaan TJ, Vaccaro WD, Webb H, Falick AM, Miller TA. Oxazolophanes as masked cyclopeptide alkaloid equivalents: cyclic peptide chemistry without peptide couplings Journal of the American Chemical Society. 112: 7032-7041. DOI: 10.1021/Ja00175A039 |
0.59 |
|
| 1990 |
Lipshutz BH, Huff BE, McCarthy KE, Miller TA, Jaweed Mukarram SM, Siahaan TJ, Vaccaro WD, Webb H, Falick AM. Oxazolophanes as masked cyclopeptide alkaloid equivalents: Cyclic peptide chemistry without peptide couplings Journal of the American Chemical Society. 112: 7032-7041. |
0.326 |
|
| 1989 |
Lipshutz BH, Ellsworth EL, Siahaan TJ. The Role of BF3·Et2O in Reactions of Lower Order (Gilman) Organocuprates Journal of the American Chemical Society. 111: 1351-1358. DOI: 10.1021/Ja00186A031 |
0.425 |
|
| 1988 |
Lipshutz BH, Ellsworth EL, Siahaan TJ. Effects of BF3•Et2O on higher order organocuprate reactions: substrate activation or cuprate modification Journal of the American Chemical Society. 110: 4834-4835. DOI: 10.1021/Ja00222A055 |
0.441 |
|
| 1988 |
Lipshutz BH, Ellsworth EL, Siahaan TJ, Shirazi A. Unexpected affects of Me3Si-X on reactions of higher order cyanocuprates Tetrahedron Letters. 29: 6677-6680. DOI: 10.1016/S0040-4039(00)82426-0 |
0.431 |
|
| 1988 |
Jolad SD, Timmermann BN, Hoffmann JJ, Bates RB, Camou FA, Siahaan TJ. Kolavane diterpenoids of Vanclevea stylosa Phytochemistry. 27: 505-515. DOI: 10.1016/0031-9422(88)83131-5 |
0.484 |
|
| 1988 |
Jolad SD, Timmermann BN, Hoffmann JJ, Bates RB, Camou FA, Siahaan TJ. Grindelane diterpenoids from Isocoma tenuisecta Phytochemistry. 27: 497-499. DOI: 10.1016/0031-9422(88)83129-7 |
0.484 |
|
| 1988 |
Jolad SD, Timmermann BN, Hoffmann JJ, Bates RB, Camou FA, Siahaan TJ. Sesquiterpenoid glycosides and an acetogenin glucoside from Lessingia glandulifera Phytochemistry. 27: 2199-2204. DOI: 10.1016/0031-9422(88)80126-2 |
0.457 |
|
| 1987 |
Sardesai LG, Paknikar SK, Bates RB, Siahaan TJ, Kane VV, Mishra PK. A new heterocyclic system from salol and phenylacetic acid Heterocycles. 26: 2941-2944. DOI: 10.3987/R-1987-11-2941 |
0.478 |
|
| 1987 |
Bates RB, Siahaan TJ, Suvannachut K, Vasey SK, Yager KM. Preparation and reactions of trianions from the dimethylphenols Journal of Organic Chemistry. 52: 4605-4608. DOI: 10.1021/Jo00229A032 |
0.465 |
|
| 1987 |
Hoffmann JJ, Jolad SD, Timmermann BN, Bates RB, Camou FA, Siahaan TJ. A new diterpenoid from Ericameria laricifolia Phytochemistry. 26: 2861-2863. DOI: 10.1016/S0031-9422(00)83610-9 |
0.498 |
|
| 1987 |
Jolad SD, Timmermann BN, Hoffmann JJ, Bates RB, Siahaan TJ. Havardic acids A-F and havardiol, labdane diterpenoids from Grindelia havardii Phytochemistry. 26: 483-489. DOI: 10.1016/S0031-9422(00)81438-7 |
0.479 |
|
| 1987 |
Timmermann BN, Hoffmann JJ, Jolad SD, Bates RB, Siahaan TJ. Five grindelane diterpenoids from Grindelia acutifolia Phytochemistry. 26: 467-470. DOI: 10.1016/S0031-9422(00)81434-X |
0.482 |
|
| 1986 |
Bates RB, Roberts SA, Siahaan TJ, Gnanasambandan T, Yalkowsky SH. 9,10-Anthracenedicarbaldehyde bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] acetic acid hydrochloric acid trihydrate salt (bisantrene) Acta Crystallographica Section C Crystal Structure Communications. 42: 186-188. DOI: 10.1107/S010827018609683X |
0.477 |
|
| 1986 |
Bates RB, Siahaan TJ. Preparation and reactions of dianions from cresols Journal of Organic Chemistry. 51: 1432-1434. DOI: 10.1021/Jo00359A010 |
0.479 |
|
| 1986 |
Jolad SD, Bates RB, Cole JR, Hoffmann JJ, Siahaan TJ, Timmermann BN. Cardenolides and a lignan from asclepias subulata Phytochemistry. 25: 2581-2590. DOI: 10.1016/S0031-9422(00)84515-X |
0.471 |
|
| 1986 |
Timmermann BN, Hoffmann JJ, Jolad SD, Bates RB, Siahaan TJ. Labdane diterpenoids from Grindelia discoidea (asteraceae) Phytochemistry. 25: 1389-1392. DOI: 10.1016/S0031-9422(00)81295-9 |
0.478 |
|
| 1986 |
Timmermann BN, Hoffmann JJ, Jolad SD, Bates RB, Siahaan TJ. Diterpenoids and flavonoids from Grindelia discoidea Phytochemistry. 25: 723-727. DOI: 10.1016/0031-9422(86)88032-3 |
0.481 |
|
| 1986 |
Bates RB, Siahaan TJ. Preparation and reactions of dianions from the cresols Journal of Organic Chemistry. 51: 1432-1434. DOI: 10.1002/Chin.198648129 |
0.465 |
|
| 1985 |
Bates RB, Camou FA, Siahaan TJ, White JJ. Resonance-stabilized dianions in synthesis Preprints Symposia. 30: 570-572. |
0.416 |
|
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