William E. Rainey - Publications

Affiliations: 
Georgia Regents University 
Area:
Physiology Biology, Endocrinology Biology, Biochemistry

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rege J, Bandulik S, Nanba K, Kosmann C, Blinder AR, Plain A, Vats P, Kumar-Sinha C, Lerario AM, Else T, Yamazaki Y, Satoh F, Sasano H, Giordano TJ, Williams TA, ... ... Rainey WE, et al. Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism. Nature Genetics. PMID 37709865 DOI: 10.1038/s41588-023-01498-5  0.555
2023 Mohan DR, Borges KS, Finco I, LaPensee CR, Rege J, Solon AL, Little DW, Else T, Almeida MQ, Dang D, Haggerty-Skeans J, Apfelbaum AA, Vinco M, Wakamatsu A, Mariani BMP, ... ... Rainey WE, et al. β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer. Cancer Research. PMID 37129912 DOI: 10.1158/0008-5472.CAN-22-2712  0.513
2022 Ghayee HK, Xu Y, Hatch H, Brockway R, Multani AS, Gu T, Bollag WB, Turcu A, Rainey WE, Rege J, Nanba K, Bhagwandin VJ, Nwariaku F, Stastny V, Gazdar AF, et al. Development of Human Adrenocortical Adenoma (HAA1) Cell Line from Zona Reticularis. International Journal of Molecular Sciences. 24. PMID 36614027 DOI: 10.3390/ijms24010584  0.566
2021 Wellman K, Fu R, Baldwin A, Rege J, Murphy E, Rainey WE, Mukherjee N. Transcriptomic Response Dynamics of Human Primary and Immortalized Adrenocortical Cells to Steroidogenic Stimuli. Cells. 10. PMID 34572026 DOI: 10.3390/cells10092376  0.566
2021 Rege J, Hoxie J, Liu CJ, Cash MN, Luther JM, Gellert L, Turcu AF, Else T, Giordano TJ, Udager AM, Rainey WE, Nanba K. Targeted Mutational Analysis of Cortisol-Producing Adenomas. The Journal of Clinical Endocrinology and Metabolism. PMID 34534321 DOI: 10.1210/clinem/dgab682  0.545
2021 Turcu AF, Zhao L, Chen X, Yang R, Rege J, Rainey WE, Veldhuis JD, Auchus RJ. Circadian Rhythms of 11-oxygenated C19 Steroids and ∆5-Steroid Sulfates in Healthy Men. European Journal of Endocrinology. PMID 34324429 DOI: 10.1530/EJE-21-0348  0.524
2021 Teuber JP, Nanba K, Turcu AF, Chen X, Zhao L, Else T, Auchus RJ, Rainey WE, Rege J. Intratumoral Steroid Profiling of Adrenal Cortisol-Producing Adenomas by Liquid Chromatography- Mass Spectrometry. The Journal of Steroid Biochemistry and Molecular Biology. 105924. PMID 34089832 DOI: 10.1016/j.jsbmb.2021.105924  0.55
2021 Fu R, Wellman K, Baldwin A, Rege J, Walters K, Hirsekorn A, Riemondy K, Rainey WE, Mukherjee N. RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells. Rna (New York, N.Y.). PMID 34074709 DOI: 10.1261/rna.078727.121  0.556
2021 Baker JE, Plaska SW, Qin Z, Liu CJ, Rege J, Rainey WE, Udager AM. Targeted RNA sequencing of adrenal zones using immunohistochemistry-guided capture of formalin-fixed paraffin-embedded tissue. Molecular and Cellular Endocrinology. 111296. PMID 33915228 DOI: 10.1016/j.mce.2021.111296  0.528
2021 Lim JS, Plaska SW, Rege J, Rainey WE, Turcu AF. Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations. Frontiers in Endocrinology. 12: 644382. PMID 33796077 DOI: 10.3389/fendo.2021.644382  0.579
2021 Tezuka Y, Atsumi N, Blinder AR, Rege J, Giordano TJ, Rainey WE, Turcu AF. The Age-Dependent Changes of the Human Adrenal Cortical Zones Are Not Congruent. The Journal of Clinical Endocrinology and Metabolism. PMID 33524149 DOI: 10.1210/clinem/dgab007  0.488
2020 Rege J, Nanba K, Blinder AR, Plaska S, Udager AM, Vats P, Kumar-Sinha C, Giordano TJ, Rainey WE, Else T. Identification of Somatic Mutations in in Aldosterone-Producing Adenomas. Journal of the Endocrine Society. 4: bvaa123. PMID 33033789 DOI: 10.1210/jendso/bvaa123  0.548
2020 Nanba K, Yamazaki Y, Bick N, Onodera K, Tezuka Y, Omata K, Ono Y, Blinder AR, Tomlins SA, Rainey WE, Satoh F, Sasano H. Prevalence of somatic mutations in aldosterone-producing adenomas in Japanese. The Journal of Clinical Endocrinology and Metabolism. PMID 32844168 DOI: 10.1210/Clinem/Dgaa595  0.307
2020 Plaska SW, Liu CJ, Lim JS, Rege J, Bick NR, Lerario AM, Hammer GD, Giordano TJ, Else T, Tomlins SA, Rainey WE, Udager AM. Targeted RNAseq of Formalin-Fixed Paraffin-Embedded Tissue to Differentiate Among Benign and Malignant Adrenal Cortical Tumors. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 52: 607-613. PMID 32791542 DOI: 10.1055/A-1212-8803  0.582
2020 Guo Z, Nanba K, Udager A, McWhinney BC, Ungerer JPJ, Wolley M, Thuzar M, Gordon RD, Rainey WE, Stowasser M. Biochemical, Histopathological and Genetic Characterization of Posture Responsive and Unresponsive APAs. The Journal of Clinical Endocrinology and Metabolism. PMID 32516371 DOI: 10.1210/Clinem/Dgaa367  0.303
2020 Davio A, Woolcock H, Nanba AT, Rege J, O'Day P, Ren J, Zhao L, Ebina H, Auchus R, Rainey WE, Turcu AF. Sex Differences in 11-Oxygenated Androgen Patterns across Adulthood. The Journal of Clinical Endocrinology and Metabolism. PMID 32498089 DOI: 10.1210/Clinem/Dgaa343  0.56
2020 Lim JS, Rainey WE. The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. PMID 32227317 DOI: 10.1055/A-1128-0421  0.401
2020 Rege J, Turcu AF, Rainey WE. Primary aldosteronism diagnostics: mutations and hybrid steroid synthesis in aldosterone-producing adenomas. Gland Surgery. 9: 3-13. PMID 32206594 DOI: 10.21037/Gs.2019.10.22  0.613
2020 Turcu AF, Rege J, Auchus RJ, Rainey WE. 11-Oxygenated androgens in health and disease. Nature Reviews. Endocrinology. PMID 32203405 DOI: 10.1038/S41574-020-0336-X  0.612
2020 De Sousa K, Boulkroun S, Baron S, Nanba K, Wack M, Rainey WE, Rocha A, Giscos-Douriez I, Meatchi T, Amar L, Travers S, Fernandes-Rosa FL, Zennaro MC. Genetic, Cellular, and Molecular Heterogeneity in Adrenals With Aldosterone-Producing Adenoma. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11914. PMID 32114847 DOI: 10.1161/Hypertensionaha.119.14177  0.375
2020 Hattangady NG, Foster J, Lerario AM, Ponce-Balbuena D, Rege J, Monticone S, Rainey WE, Mulatero P, Else T. Molecular and Electrophysiological Analyses of ATP2B4 Gene Variants in Bilateral Adrenal Hyperaldosteronism. Hormones & Cancer. PMID 32002807 DOI: 10.1007/S12672-019-00375-0  0.625
2020 Nanba K, Blinder AR, Rege J, Hattangady NG, Else T, Liu CJ, Tomlins SA, Vats P, Kumar-Sinha C, Giordano TJ, Rainey WE. Somatic Mutation As a Cause of Aldosterone-Producing Adenoma. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11914. PMID 31983310 DOI: 10.1161/Hypertensionaha.119.14349  0.611
2020 Plaska S, Baker J, Blinder A, Lim JS, Rainey WE. OR19-01 IHC-Guided Capture of Adrenocortical Zones from Archival Formalin-Fixed, Paraffin-Embedded Adrenal Tissue Allows the Study Of RNA Expression Profiles Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.939  0.301
2020 Baker JE, Nanba K, Blinder AR, Bick N, Wachtel H, Cohen DL, Williams TA, Reincke M, Else T, Tomlins SA, Giordano TJ, Rainey WE. SAT-554 Genetic Profile of Early-Onset Aldosterone-Producing Adenomas Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.910  0.372
2020 Lim JS, Plaska S, Rege J, Turcu AF, Rainey WE. SAT-LB90 Angiotensin II and ACTH Receptor Expression in Aldosterone-Producing Adenomas Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2318  0.622
2020 Mohan DR, Finco I, LaPensee CR, Rege J, Else T, Almeida MQ, Vinco M, Wakamatsu A, Latronico AC, Mendonca BB, Zerbini MCN, Fragoso MCBV, Rainey WE, Venneti S, Marie SKN, et al. SAT-LB34 Repressive Epigenetic Programs Reinforce Steroidogenic Differentiation and Wnt/β-Catenin Signaling in Aggressive Adrenocortical Carcinoma Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2265  0.56
2020 Rege J, Nanba K, Blinder AR, Else T, Tomlins S, Vats P, Kumar-Sinha C, Giordano TJ, Rainey WE. SAT-549 Identification of Somatic Mutations in CLCN2 as a Cause of Aldosterone-Producing Adenomas Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1782  0.591
2020 Nocito MC, Saraithong P, Newman EA, Thomas IH, Rainey WE, Lerario AM, Heider A, Else T. SUN-931 Characterization of an Ovarian Steroid Cell Tumor in a VHL Patient Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1344  0.352
2020 Tsomos E, Belokovskaya R, Escobar JS, Yao S, Nanba K, Haines K, Rainey WE, Kirschenbaum A, Levine AC. OR19-02 Luteinizing Hormone/Human Chorionic Gonadotropin Receptor Protein Expression in Adrenocortical Progenitor Cells, Aldosterone Producing Cell Clusters and Adrenal Adenomas Derived from Postmenopausal Women Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1076  0.344
2019 Ono Y, Yamazaki Y, Omata K, Else T, Tomlins SA, Rhayem Y, Williams TA, Reincke M, Carling T, Monticone S, Mulatero P, Beuschlein F, Ito S, Satoh F, Rainey WE, et al. Histological characterization of aldosterone-producing adrenocortical adenomas with different somatic mutations. The Journal of Clinical Endocrinology and Metabolism. PMID 31789380 DOI: 10.1210/Clinem/Dgz235  0.327
2019 Turcu AF, Wannachalee T, Tsodikov A, Nanba AT, Ren J, Shields JJ, O'Day PJ, Giacherio D, Rainey WE, Auchus RJ. Comprehensive Analysis of Steroid Biomarkers for Guiding Primary Aldosteronism Subtyping. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31786984 DOI: 10.1161/Hypertensionaha.119.13866  0.313
2019 Taylor MJ, Ullenbruch MR, Frucci EC, Rege J, Ansorge MS, Gomez-Sanchez CE, Begum S, Laufer E, Breault DT, Rainey WE. Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation. The Journal of Clinical Investigation. PMID 31738186 DOI: 10.1172/Jci127429  0.601
2019 Wannachalee T, Zhao L, Nanba K, Nanba AT, Shields JJ, Rainey WE, Auchus RJ, Turcu AF. Three Discrete Patterns of Primary Aldosteronism Lateralization in Response to Cosyntropin during Adrenal Vein Sampling. The Journal of Clinical Endocrinology and Metabolism. PMID 31408156 DOI: 10.1210/Jc.2019-01182  0.304
2019 Rege J, Garber S, Conley AJ, Elsey RM, Turcu AF, Auchus RJ, Rainey WE. Circulating 11-oxygenated androgens across species. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30959151 DOI: 10.1016/J.Jsbmb.2019.04.005  0.585
2019 Mohan DR, Lerario AM, Else T, Mukherjee B, Almeida MQ, Vinco M, Rege J, Mariani BMP, Zerbini MCN, Mendonca BB, Latronico AC, Marie SKN, Rainey WE, Giordano TJ, Fragoso MCBV, et al. Targeted assessment of methylation identifies a rapidly recurrent, routinely fatal molecular subtype of adrenocortical carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30770352 DOI: 10.1158/1078-0432.Ccr-18-2693  0.547
2019 Nanba AT, Rege J, Ren J, Auchus RJ, Rainey WE, Turcu AF. 11-Oxygenated C19 Steroids Do Not Decline with Age in Women. The Journal of Clinical Endocrinology and Metabolism. PMID 30753518 DOI: 10.1210/Jc.2018-02527  0.542
2019 Lerario AM, Nanba K, Blinder AR, Suematsu S, Omura M, Nishikawa T, Giordano TJ, Rainey W, Else T. Genetics of aldosterone-producing adenomas with pathogenic KCNJ5 variants. Endocrine-Related Cancer. PMID 30753137 DOI: 10.1530/Erc-18-0364  0.342
2019 Nanba K, Omata K, Gomez-Sanchez CE, Stratakis CA, Demidowich AP, Suzuki M, Thompson LDR, Cohen DL, Luther JM, Gellert L, Vaidya A, Barletta JA, Else T, Giordano TJ, Tomlins SA, ... Rainey WE, et al. Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11812. PMID 30739536 DOI: 10.1161/Hypertensionaha.118.12070  0.335
2019 Rege J, Turcu AF, Else T, Auchus RJ, Rainey WE. Steroid Biomarkers in Human Adrenal Disease. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30707926 DOI: 10.1016/J.Jsbmb.2019.01.018  0.615
2019 Affinati A, Rege J, Nanba K, Blinder A, He X, Miller B, Samantray J, Rainey W, Auchus R. SUN-387 ACTH-Independent Cushing Syndrome from Pregnancy-Induced Micronodular Hyperplasia Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-387  0.535
2019 Rege J, Garber S, Auchus R, Turcu A, Conley A, Rainey W. SAT-345 11-oxygenated Adrenal Androgens Are Produced In Several Mammalian Species Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-345  0.539
2019 Namba A, Rege J, Rainey W, Auchus R, Turcu A. SAT-010 Adrenal Androgen Synthesis in Aging Men Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-010  0.545
2019 Mohan D, Lerario A, Else T, Almeida M, Vinco M, Rege J, Mariani B, Zerbini M, Mendonca B, Latronico AC, Marie S, Rainey W, Giordano T, Fragoso M, Hammer G. OR29-3 Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or29-3  0.534
2018 Mouat IC, Omata K, McDaniel AS, Hattangady N, Talapatra D, Cani AK, Hovelson DH, Tomlins SA, Rainey W, Hammer G, Giordano TJ, Else T. Somatic mutations in adrenocortical carcinoma with hyperaldosteronism. Endocrine-Related Cancer. PMID 30475217 DOI: 10.1530/Erc-18-0385  0.362
2018 Omata K, Satoh F, Morimoto R, Ito S, Yamazaki Y, Nakamura Y, Anand SK, Guo Z, Stowasser M, Sasano H, Tomlins SA, Rainey WE. Cellular and Genetic Causes of Idiopathic Hyperaldosteronism. Hypertension (Dallas, Tex. : 1979). 72: 874-880. PMID 30354720 DOI: 10.1161/Hypertensionaha.118.11086  0.374
2018 Nanba AT, Wannachalee T, Shields JJ, Byrd JB, Rainey WE, Auchus RJ, Turcu AF. Adrenal Vein Sampling Lateralization Despite Mineralocorticoid Receptor Antagonists Exposure in Primary Aldosteronism. The Journal of Clinical Endocrinology and Metabolism. PMID 30239792 DOI: 10.1210/Jc.2018-01299  0.305
2018 Rege J, Turcu A, Kasa-Vubu JZ, Lerario AM, Auchus GC, Auchus RJ, Smith JM, White PC, Rainey WE. 11-ketotestosterone is the dominant circulating bioactive androgen during normal and premature adrenarche. The Journal of Clinical Endocrinology and Metabolism. PMID 30137510 DOI: 10.1210/Jc.2018-00736  0.585
2018 Nanba K, Omata K, Else T, Beck PCC, Nanba AT, Turcu AF, Miller BS, Giordano TJ, Tomlins SA, Rainey WE. Targeted Molecular Characterization of Aldosterone-Producing Adenomas in White Americans. The Journal of Clinical Endocrinology and Metabolism. PMID 30085035 DOI: 10.1210/Jc.2018-01004  0.32
2018 Sun N, Wu Y, Nanba K, Sbiera S, Kircher S, Kunzke T, Aichler M, Berezowska S, Reibetanz J, Rainey WE, Fassnacht M, Walch A, Kroiss M. High resolution tissue mass spectrometry imaging reveals a refined functional anatomy of the human adult adrenal gland. Endocrinology. PMID 29385420 DOI: 10.1210/En.2018-00064  0.328
2017 Casaburi I, Avena P, De Luca A, Sirianni R, Rago V, Chimento A, Trotta F, Campana C, Rainey WE, Pezzi V. GPER-independent inhibition of adrenocortical cancer growth by G-1 involves ROS/Egr-1/BAX pathway. Oncotarget. 8: 115609-115619. PMID 29383185 DOI: 10.18632/Oncotarget.23314  0.3
2017 Omata K, Anand SK, Hovelson DH, Liu CJ, Yamazaki Y, Nakamura Y, Ito S, Satoh F, Sasano H, Rainey WE, Tomlins SA. Aldosterone-Producing Cell Clusters Frequently Harbor Somatic Mutations and Accumulate With Age in Normal Adrenals. Journal of the Endocrine Society. 1: 787-799. PMID 29264530 DOI: 10.1210/Js.2017-00134  0.348
2017 Nanba K, Vaidya A, Rainey WE. Aging and Adrenal Aldosterone Production. Hypertension (Dallas, Tex. : 1979). PMID 29229745 DOI: 10.1161/Hypertensionaha.117.10391  0.397
2017 Omata K, Tomlins SA, Rainey WE. Aldosterone-Producing Cell Clusters in Normal and Pathological States. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 49: 951-956. PMID 29202494 DOI: 10.1055/S-0043-122394  0.362
2017 Rege J, Nanba AT, Auchus RJ, Ren J, Peng HM, Rainey WE, Turcu AF. Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal in Vivo and in Vitro. The Journal of Clinical Endocrinology and Metabolism. PMID 29126147 DOI: 10.1210/Jc.2017-01525  0.594
2017 Gomez-Sanchez CE, Lewis M, Nanba K, Rainey WE, Kuppusamy M, Gomez-Sanchez EP. Development of Monoclonal Antibodies Against the Human 3β-Hydroxysteroid Dehydrogenase/Isomerase Isozymes. Steroids. PMID 28863887 DOI: 10.1016/J.Steroids.2017.08.011  0.34
2017 Suzuki D, Saito-Hakoda A, Ito R, Shimizu K, Parvin R, Shimada H, Noro E, Suzuki S, Fujiwara I, Kagechika H, Rainey WE, Kure S, Ito S, Yokoyama A, Sugawara A. Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure. Plos One. 12: e0181055. PMID 28800627 DOI: 10.1371/Journal.Pone.0181055  0.342
2016 Tsai YY, Rainey WE, Bollag WB. Very low-density lipoprotein (VLDL)-induced signals mediating aldosterone production. The Journal of Endocrinology. PMID 27913572 DOI: 10.1530/Joe-16-0237  0.304
2016 Rege J, Karashima S, Lerario AM, Smith JM, Auchus RJ, Kasa-Vubu JZ, Sasano H, Nakamura Y, White PC, Rainey WE. Age-dependent increases in adrenal cytochrome b5 and serum 5-androstenediol-3-sulfate. The Journal of Clinical Endocrinology and Metabolism. jc20162864. PMID 27623070 DOI: 10.1210/Jc.2016-2864  0.59
2016 Tsai YY, Rainey WE, Johnson MH, Bollag WB. VLDL-activated cell signaling pathways that stimulate adrenal cell aldosterone production. Molecular and Cellular Endocrinology. PMID 27222295 DOI: 10.1016/J.Mce.2016.05.018  0.327
2016 Nanba K, Omata K, Tomlins SA, Giordano TJ, Hammer G, Rainey WE, Else T. Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations. European Journal of Endocrinology / European Federation of Endocrine Societies. PMID 27165862 DOI: 10.1530/Eje-16-0262  0.352
2016 Hattangady NG, Karashima S, Yuan L, Ponce-Balbuena D, Jalife J, Gomez-Sanchez CE, Auchus R, Rainey WE, Else T. Mutated KCNJ5 activates the acute and chronic regulatory steps in aldosterone production. Journal of Molecular Endocrinology. PMID 27099398 DOI: 10.1530/Jme-15-0324  0.378
2016 Nanba K, Chen AX, Omata K, Vinco M, Giordano TJ, Else T, Hammer GD, Tomlins SA, Rainey WE. Molecular Heterogeneity in Aldosterone-Producing Adenomas. The Journal of Clinical Endocrinology and Metabolism. jc20153239. PMID 26765578 DOI: 10.1210/Jc.2015-3239  0.344
2016 Campana C, Rege J, Turcu AF, Pezzi V, Gomez-Sanchez CE, Robins DM, Rainey WE. Development of a novel cell based androgen screening model. The Journal of Steroid Biochemistry and Molecular Biology. 156: 17-22. PMID 26581480 DOI: 10.1016/J.Jsbmb.2015.11.005  0.608
2015 Nanba K, Chen AX, Turcu AF, Rainey WE. H295R expression of melanocortin 2 receptor accessory protein (MRAP) results in ACTH responsiveness. Journal of Molecular Endocrinology. PMID 26576642 DOI: 10.1530/Jme-15-0230  0.38
2015 Chen AX, Nishimoto K, Nanba K, Rainey WE. Potassium channels related to primary aldosteronism: expression similarities and differences between human and rat adrenals. Molecular and Cellular Endocrinology. PMID 26375812 DOI: 10.1016/J.Mce.2015.09.011  0.359
2015 Nishimoto K, Tomlins SA, Kuick R, Cani AK, Giordano TJ, Hovelson DH, Liu CJ, Sanjanwala AR, Edwards MA, Gomez-Sanchez CE, Nanba K, Rainey WE. Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands. Proceedings of the National Academy of Sciences of the United States of America. PMID 26240369 DOI: 10.1073/Pnas.1505529112  0.393
2015 Xing Y, Lerario AM, Rainey W, Hammer GD. Development of adrenal cortex zonation. Endocrinology and Metabolism Clinics of North America. 44: 243-74. PMID 26038200 DOI: 10.1016/J.Ecl.2015.02.001  0.327
2015 Campana C, Pezzi V, Rainey WE. Cell-based assays for screening androgen receptor ligands. Seminars in Reproductive Medicine. 33: 225-34. PMID 26036905 DOI: 10.1055/S-0035-1552989  0.318
2015 Rege J, Nishimoto HK, Nishimoto K, Rodgers RJ, Auchus RJ, Rainey WE. Bone Morphogenetic Protein-4 (BMP4): A Paracrine Regulator of Human Adrenal C19 Steroid Synthesis. Endocrinology. 156: 2530-40. PMID 25868050 DOI: 10.1210/En.2014-1942  0.603
2015 Turcu AF, Rege J, Chomic R, Liu J, Nishimoto HK, Else T, Moraitis AG, Palapattu GS, Rainey WE, Auchus RJ. Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency. The Journal of Clinical Endocrinology and Metabolism. 100: 2283-90. PMID 25850025 DOI: 10.1210/Jc.2015-1023  0.541
2015 Nanba K, Chen A, Nishimoto K, Rainey WE. Role of Ca(2+)/calmodulin-dependent protein kinase kinase in adrenal aldosterone production. Endocrinology. 156: 1750-6. PMID 25679868 DOI: 10.1210/En.2014-1782  0.339
2015 Recarti C, Seccia TM, Caroccia B, Gonzales-Campos A, Ceolotto G, Lenzini L, Petrelli L, Belloni AS, Rainey WE, Nussberger J, Rossi GP. Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism. Journal of Hypertension. 33: 1014-22. PMID 25668351 DOI: 10.1097/Hjh.0000000000000504  0.337
2015 Monticone S, Else T, Mulatero P, Williams TA, Rainey WE. Understanding primary aldosteronism: impact of next generation sequencing and expression profiling. Molecular and Cellular Endocrinology. 399: 311-20. PMID 25240470 DOI: 10.1016/J.Mce.2014.09.015  0.328
2015 Nakamura Y, Fujishima F, Hui XG, Felizola SJ, Shibahara Y, Akahira J, McNamara KM, Rainey WE, Sasano H. 3βHSD and CYB5A double positive adrenocortical cells during adrenal development/aging. Endocrine Research. 40: 8-13. PMID 24832628 DOI: 10.3109/07435800.2014.895377  0.346
2015 Boulkroun S, Rickard A, Golib Dzib J, Samson-Couterie B, Rocha A, Gomez-Sanchez C, Rainey W, Amar L, Fernandes-Rosa F, Ghyselinck N, Benecke A, Lalli E, Zennaro M. CO-34: Retinoic acid receptor signaling contributes to adrenal morphology and functional zonation Annales De Cardiologie Et D'AngéIologie. 64: S16. DOI: 10.1016/S0003-3928(16)30034-8  0.343
2014 Turcu A, Smith JM, Auchus R, Rainey WE. Adrenal androgens and androgen precursors-definition, synthesis, regulation and physiologic actions. Comprehensive Physiology. 4: 1369-81. PMID 25428847 DOI: 10.1002/Cphy.C140006  0.351
2014 Tsai YY, Rainey WE, Pan ZQ, Frohman MA, Choudhary V, Bollag WB. Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells. Endocrinology. 155: 3550-60. PMID 24956203 DOI: 10.1210/En.2014-1159  0.31
2014 Nakamura Y, Maekawa T, Felizola SJ, Satoh F, Qi X, Velarde-Miranda C, Plonczynski MW, Ise K, Kikuchi K, Rainey WE, Gomez-Sanchez EP, Gomez-Sanchez CE, Sasano H. Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies. Molecular and Cellular Endocrinology. 392: 73-9. PMID 24837548 DOI: 10.1016/J.Mce.2014.05.002  0.359
2014 Nakamura Y, Hattangady NG, Ye P, Satoh F, Morimoto R, Ito-Saito T, Sugawara A, Ohba K, Takahashi K, Rainey WE, Sasano H. Aberrant gonadotropin-releasing hormone receptor (GnRHR) expression and its regulation of CYP11B2 expression and aldosterone production in adrenal aldosterone-producing adenoma (APA). Molecular and Cellular Endocrinology. 384: 102-8. PMID 24472523 DOI: 10.1016/J.Mce.2014.01.016  0.397
2014 Rege J, Nakamura Y, Wang T, Merchen TD, Sasano H, Rainey WE. Transcriptome profiling reveals differentially expressed transcripts between the human adrenal zona fasciculata and zona reticularis. The Journal of Clinical Endocrinology and Metabolism. 99: E518-27. PMID 24423296 DOI: 10.1210/Jc.2013-3198  0.618
2014 Nishimoto K, Harris RB, Rainey WE, Seki T. Sodium deficiency regulates rat adrenal zona glomerulosa gene expression. Endocrinology. 155: 1363-72. PMID 24422541 DOI: 10.1210/En.2013-1999  0.347
2014 Matsuda K, Uruno A, Kogure N, Sugawara K, Shimada H, Nezu M, Saito-Ito T, Iki Y, Kudo M, Shimizu K, Sato I, Yoshikawa T, Satoh F, Ito R, Yokoyama A, ... Rainey WE, et al. Angiotensin II receptor blockers differentially affect CYP11B2 expression in human adrenal H295R cells. Molecular and Cellular Endocrinology. 383: 60-8. PMID 24333837 DOI: 10.1016/J.Mce.2013.12.004  0.335
2014 Felizola SJ, Nakamura Y, Arata Y, Ise K, Satoh F, Rainey WE, Midorikawa S, Suzuki S, Sasano H. Metallothionein-3 (MT-3) in the human adrenal cortex and its disorders. Endocrine Pathology. 25: 229-35. PMID 24242700 DOI: 10.1007/S12022-013-9280-9  0.35
2013 Moraitis AG, Rainey WE, Auchus RJ. Gene mutations that promote adrenal aldosterone production, sodium retention, and hypertension. The Application of Clinical Genetics. 7: 1-13. PMID 24399884 DOI: 10.2147/Tacg.S35571  0.352
2013 Swart AC, Schloms L, Storbeck KH, Bloem LM, Toit Td, Quanson JL, Rainey WE, Swart P. 11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione. The Journal of Steroid Biochemistry and Molecular Biology. 138: 132-42. PMID 23685396 DOI: 10.1016/J.Jsbmb.2013.04.010  0.341
2013 Rege J, Nakamura Y, Satoh F, Morimoto R, Kennedy MR, Layman LC, Honma S, Sasano H, Rainey WE. Liquid chromatography-tandem mass spectrometry analysis of human adrenal vein 19-carbon steroids before and after ACTH stimulation. The Journal of Clinical Endocrinology and Metabolism. 98: 1182-8. PMID 23386646 DOI: 10.1210/Jc.2012-2912  0.572
2013 Nishimoto K, Rainey WE, Bollag WB, Seki T. Lessons from the gene expression pattern of the rat zona glomerulosa. Molecular and Cellular Endocrinology. 371: 107-13. PMID 23287491 DOI: 10.1016/J.Mce.2012.12.023  0.323
2013 Mulatero P, Monticone S, Rainey WE, Veglio F, Williams TA. Role of KCNJ5 in familial and sporadic primary aldosteronism. Nature Reviews. Endocrinology. 9: 104-12. PMID 23229280 DOI: 10.1038/Nrendo.2012.230  0.331
2013 Felizola SJ, Nakamura Y, Hui XG, Satoh F, Morimoto R, M McNamara K, Midorikawa S, Suzuki S, Rainey WE, Sasano H. Estrogen-related receptor α in normal adrenal cortex and adrenocortical tumors: involvement in development and oncogenesis. Molecular and Cellular Endocrinology. 365: 207-11. PMID 23123734 DOI: 10.1016/J.Mce.2012.10.020  0.344
2012 Rege J, Rainey WE. The steroid metabolome of adrenarche. The Journal of Endocrinology. 214: 133-43. PMID 22715193 DOI: 10.1530/Joe-12-0183  0.587
2012 Monticone S, Hattangady NG, Nishimoto K, Mantero F, Rubin B, Cicala MV, Pezzani R, Auchus RJ, Ghayee HK, Shibata H, Kurihara I, Williams TA, Giri JG, Bollag RJ, Edwards MA, ... ... Rainey WE, et al. Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells. The Journal of Clinical Endocrinology and Metabolism. 97: E1567-72. PMID 22628608 DOI: 10.1210/Jc.2011-3132  0.342
2012 Monticone S, Satoh F, Giacchetti G, Viola A, Morimoto R, Kudo M, Iwakura Y, Ono Y, Turchi F, Paci E, Veglio F, Boscaro M, Rainey W, Ito S, Mulatero P. Effect of adrenocorticotropic hormone stimulation during adrenal vein sampling in primary aldosteronism. Hypertension. 59: 840-6. PMID 22331382 DOI: 10.1161/Hypertensionaha.111.189548  0.325
2012 Wang T, Rowland JG, Parmar J, Nesterova M, Seki T, Rainey WE. Comparison of aldosterone production among human adrenocortical cell lines Hormone and Metabolic Research. 44: 245-250. PMID 22266826 DOI: 10.1055/S-0031-1298019  0.323
2012 Xing Y, Rainey WE, Apolzan JW, Francone OL, Harris RB, Bollag WB. Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL). Endocrinology. 153: 721-31. PMID 22186415 DOI: 10.1210/En.2011-1752  0.372
2012 Nakamura Y, Rege J, Satoh F, Morimoto R, Kennedy MR, Ahlem CN, Honma S, Sasano H, Rainey WE. Liquid chromatography-tandem mass spectrometry analysis of human adrenal vein corticosteroids before and after adrenocorticotropic hormone stimulation. Clinical Endocrinology. 76: 778-84. PMID 22150161 DOI: 10.1111/J.1365-2265.2011.04316.X  0.581
2012 Wang T, Rainey WE. Human adrenocortical carcinoma cell lines. Molecular and Cellular Endocrinology. 351: 58-65. PMID 21924324 DOI: 10.1016/J.Mce.2011.08.041  0.359
2012 Hattangady NG, Olala LO, Bollag WB, Rainey WE. Acute and chronic regulation of aldosterone production. Molecular and Cellular Endocrinology. 350: 151-62. PMID 21839803 DOI: 10.1016/J.Mce.2011.07.034  0.332
2011 Mansfield CW, Carr BR, Faye-Petersen OM, Chen D, Xing Y, Rainey WE, Parker CR. Differential gene expression in the adrenals of normal and anencephalic fetuses and studies focused on the Fras-1-related extracellular matrix protein (FREM2) gene. Reproductive Sciences (Thousand Oaks, Calif.). 18: 1146-53. PMID 22031191 DOI: 10.1177/1933719111408113  0.318
2011 Suda N, Shibata H, Kurihara I, Ikeda Y, Kobayashi S, Yokota K, Murai-Takeda A, Nakagawa K, Oya M, Murai M, Rainey WE, Saruta T, Itoh H. Coactivation of SF-1-mediated transcription of steroidogenic enzymes by Ubc9 and PIAS1. Endocrinology. 152: 2266-77. PMID 21467194 DOI: 10.1210/En.2010-1232  0.358
2011 Xing Y, Edwards MA, Ahlem C, Kennedy M, Cohen A, Gomez-Sanchez CE, Rainey WE. The effects of ACTH on steroid metabolomic profiles in human adrenal cells. The Journal of Endocrinology. 209: 327-35. PMID 21429963 DOI: 10.1530/Joe-10-0493  0.401
2011 Hatzirodos N, Bayne RA, Irving-Rodgers HF, Hummitzsch K, Sabatier L, Lee S, Bonner W, Gibson MA, Rainey WE, Carr BR, Mason HD, Reinhardt DP, Anderson RA, Rodgers RJ. Linkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2256-65. PMID 21411746 DOI: 10.1096/Fj.11-181099  0.313
2011 Wang T, Satoh F, Morimoto R, Nakamura Y, Sasano H, Auchus RJ, Edwards MA, Rainey WE. Gene expression profiles in aldosterone-producing adenomas and adjacent adrenal glands. European Journal of Endocrinology / European Federation of Endocrine Societies. 164: 613-9. PMID 21248073 DOI: 10.1530/Eje-10-1085  0.367
2011 Xing Y, Cohen A, Rothblat G, Sankaranarayanan S, Weibel G, Royer L, Francone OL, Rainey WE. Aldosterone production in human adrenocortical cells is stimulated by high-density lipoprotein 2 (HDL2) through increased expression of aldosterone synthase (CYP11B2). Endocrinology. 152: 751-63. PMID 21239432 DOI: 10.1210/En.2010-1049  0.321
2011 Nakamura Y, Xing Y, Hui XG, Kurotaki Y, Ono K, Cohen T, Sasano H, Rainey WE. Human adrenal cells that express both 3β-hydroxysteroid dehydrogenase type 2 (HSD3B2) and cytochrome b5 (CYB5A) contribute to adrenal androstenedione production. The Journal of Steroid Biochemistry and Molecular Biology. 123: 122-6. PMID 21185375 DOI: 10.1016/J.Jsbmb.2010.12.001  0.39
2011 Uruno A, Matsuda K, Noguchi N, Yoshikawa T, Kudo M, Satoh F, Rainey WE, Hui XG, Akahira J, Nakamura Y, Sasano H, Okamoto H, Ito S, Sugawara A. Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production. Journal of Molecular Endocrinology. 46: 37-49. PMID 21106862 DOI: 10.1677/Jme-10-0088  0.388
2011 Ghayee HK, Rege J, Watumull LM, Nwariaku FE, Carrick KS, Rainey WE, Miller WL, Auchus RJ. Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome. The Journal of Clinical Endocrinology and Metabolism. 96: E243-50. PMID 21084398 DOI: 10.1210/Jc.2010-1222  0.563
2010 Sirianni R, Nogueira E, Bassett MH, Carr BR, Suzuki T, Pezzi V, Andò S, Rainey WE. The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1. Journal of Cell Science. 123: 3956-65. PMID 20980388 DOI: 10.1242/Jcs.055806  0.332
2010 Xing Y, Parker CR, Edwards M, Rainey WE. ACTH is a potent regulator of gene expression in human adrenal cells. Journal of Molecular Endocrinology. 45: 59-68. PMID 20460446 DOI: 10.1677/Jme-10-0006  0.381
2010 Nogueira EF, Rainey WE. Regulation of aldosterone synthase by activator transcription factor/cAMP response element-binding protein family members. Endocrinology. 151: 1060-70. PMID 20097716 DOI: 10.1210/En.2009-0977  0.32
2010 Nogueira EF, Gerry D, Mantero F, Mariniello B, Rainey WE. The role of TASK1 in aldosterone production and its expression in normal adrenal and aldosterone-producing adenomas. Clinical Endocrinology. 73: 22-9. PMID 19878209 DOI: 10.1111/J.1365-2265.2009.03738.X  0.309
2009 Hui XG, Akahira J, Suzuki T, Nio M, Nakamura Y, Suzuki H, Rainey WE, Sasano H. Development of the human adrenal zona reticularis: morphometric and immunohistochemical studies from birth to adolescence. The Journal of Endocrinology. 203: 241-52. PMID 19723922 DOI: 10.1677/Joe-09-0127  0.304
2009 Nakamura Y, Xing Y, Sasano H, Rainey WE. The mediator complex subunit 1 enhances transcription of genes needed for adrenal androgen production. Endocrinology. 150: 4145-53. PMID 19497978 DOI: 10.1210/En.2009-0006  0.352
2009 Nakamura Y, Hornsby PJ, Casson P, Morimoto R, Satoh F, Xing Y, Kennedy MR, Sasano H, Rainey WE. Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularis. The Journal of Clinical Endocrinology and Metabolism. 94: 2192-8. PMID 19336506 DOI: 10.1210/Jc.2008-2374  0.347
2009 Nogueira EF, Xing Y, Morris CA, Rainey WE. Role of angiotensin II-induced rapid response genes in the regulation of enzymes needed for aldosterone synthesis. Journal of Molecular Endocrinology. 42: 319-30. PMID 19158234 DOI: 10.1677/Jme-08-0112  0.331
2009 Xing Y, Nakamura Y, Rainey WE. G protein-coupled receptor expression in the adult and fetal adrenal glands. Molecular and Cellular Endocrinology. 300: 43-50. PMID 19027826 DOI: 10.1016/J.Mce.2008.10.036  0.334
2009 Ye P, Nakamura Y, Lalli E, Rainey WE. Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells. Endocrinology. 150: 1303-9. PMID 18974272 DOI: 10.1210/En.2008-0667  0.331
2009 Nakamura Y, Gang HX, Suzuki T, Sasano H, Rainey WE. Adrenal changes associated with adrenarche. Reviews in Endocrine & Metabolic Disorders. 10: 19-26. PMID 18821019 DOI: 10.1007/S11154-008-9092-2  0.348
2009 Ye P, Yamashita T, Pollock DM, Sasano H, Rainey WE. Contrasting effects of eplerenone and spironolactone on adrenal cell steroidogenesis Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 41: 35-39. PMID 18819053 DOI: 10.1055/S-0028-1087188  0.359
2009 Nogueira EF, Bollag WB, Rainey WE. Angiotensin II regulation of adrenocortical gene transcription. Molecular and Cellular Endocrinology. 302: 230-6. PMID 18812209 DOI: 10.1016/J.Mce.2008.08.024  0.319
2008 Parmar J, Key RE, Rainey WE. Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell line. The Journal of Clinical Endocrinology and Metabolism. 93: 4542-6. PMID 18713819 DOI: 10.1210/Jc.2008-0903  0.325
2007 Nakamura Y, Aoki S, Xing Y, Sasano H, Rainey WE. Metastin stimulates aldosterone synthesis in human adrenal cells. Reproductive Sciences (Thousand Oaks, Calif.). 14: 836-45. PMID 18089602 DOI: 10.1177/1933719107307823  0.393
2007 Nogueira EF, Vargas CA, Otis M, Gallo-Payet N, Bollag WB, Rainey WE. Angiotensin-II acute regulation of rapid response genes in human, bovine, and rat adrenocortical cells. Journal of Molecular Endocrinology. 39: 365-74. PMID 18055484 DOI: 10.1677/Jme-07-0094  0.353
2007 Rehman KS, Sirianni R, Parker CR, Rainey WE, Carr BR. The regulation of adrenocorticotrophic hormone receptor by corticotropin-releasing hormone in human fetal adrenal definitive/transitional zone cells. Reproductive Sciences (Thousand Oaks, Calif.). 14: 578-87. PMID 17959886 DOI: 10.1177/1933719107307908  0.391
2007 Ye P, Mariniello B, Mantero F, Shibata H, Rainey WE. G-protein-coupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism. The Journal of Endocrinology. 195: 39-48. PMID 17911395 DOI: 10.1677/Joe-07-0037  0.337
2007 Beshay VE, Havelock JC, Sirianni R, Ye P, Suzuki T, Rainey WE, Carr BR. The mechanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model. The Journal of Clinical Endocrinology and Metabolism. 92: 4802-9. PMID 17895316 DOI: 10.1210/Jc.2007-1394  0.339
2005 Sirianni R, Mayhew BA, Carr BR, Parker CR, Rainey WE. Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells. The Journal of Clinical Endocrinology and Metabolism. 90: 5393-400. PMID 16014403 DOI: 10.1210/Jc.2005-0680  0.371
2005 Bassett MH, Mayhew B, Rehman K, White PC, Mantero F, Arnaldi G, Stewart PM, Bujalska I, Rainey WE. Expression profiles for steroidogenic enzymes in adrenocortical disease. The Journal of Clinical Endocrinology and Metabolism. 90: 5446-55. PMID 15985477 DOI: 10.1210/Jc.2005-0836  0.329
2001 Attia GR, Rainey WE, Carr BR. Metformin directly inhibits androgen production in human thecal cells Fertility and Sterility. 76: 517-524. PMID 11532475 DOI: 10.1016/S0015-0282(01)01975-6  0.358
1998 Gell JS, Oh J, Rainey WE, Carr BR. Effect of estradiol on DHEAS production in the human adrenocortical cell line, H295R. Journal of the Society For Gynecologic Investigation. 5: 144-8. PMID 9614644 DOI: 10.1016/S1071-5576(98)00002-1  0.33
1996 Carr BR, McGee EA, Sawetawan C, Clyne CD, Rainey WE, Weiss G, Jaffe RB, Hill JA. The effect of transforming growth factor-β on steroidogenesis and expression of key steroidogenic enzymes with a human ovarian thecal-like tumor cell model American Journal of Obstetrics and Gynecology. 174: 1109-1117. PMID 8623837 DOI: 10.1016/S0002-9378(96)70652-X  0.313
1990 Viard I, Rainey WE, Capponi AM, Begeot M, Saez JM. Ovine adrenal fasciculata cells contain angiotensin-II receptors coupled to intracellular effectors but are resistant to the steroidogenic effects of this hormone Endocrinology. 127: 2071-2078. PMID 2171905 DOI: 10.1210/Endo-127-5-2071  0.316
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