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Gregory T. Knipp - Publications

Affiliations: 
Industrial and Physical Pharmacy Purdue University, West Lafayette, IN, United States 
Area:
Pharmacology, Pharmaceutical Chemistry, Physiology Biology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lavan M, Knipp G. Considerations For Determining Direct Versus Indirect Functional Effects Of Solubilizing Excipients On Drug Transporters For Enahancing Bioavailability. Journal of Pharmaceutical Sciences. PMID 32142715 DOI: 10.1016/J.Xphs.2020.02.020  0.503
2019 Lavan M, Byrn SR, Knipp G. Pediatric Formulations: Knowledge Gaps Limiting the Expedited Preclinical to Clinical Translation in Children. Aaps Pharmscitech. 20: 73. PMID 30631973 DOI: 10.1208/S12249-018-1253-3  0.311
2018 Lavan M, Knipp G. Effects of Dendrimer-Like Biopolymers on Physical Stability of Amorphous Solid Dispersions and Drug Permeability Across Caco-2 Cell Monolayers. Aaps Pharmscitech. PMID 29869315 DOI: 10.1208/S12249-018-1080-6  0.35
2015 Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clinical Pharmacology and Therapeutics. 98: 266-87. PMID 26088472 DOI: 10.1002/Cpt.176  0.494
2015 Mehtala JG, Kulczar C, Lavan M, Knipp G, Wei A. Cys34-PEGylated Human Serum Albumin for Drug Binding and Delivery. Bioconjugate Chemistry. 26: 941-9. PMID 25918947 DOI: 10.1021/Acs.Bioconjchem.5B00143  0.331
2014 Krasniak AE, Knipp GT, Svensson CK, Liu W. Pharmacogenomics of acetaminophen in pediatric populations: a moving target. Frontiers in Genetics. 5: 314. PMID 25352860 DOI: 10.3389/Fgene.2014.00314  0.329
2014 Sage DP, Kulczar C, Roth W, Liu W, Knipp GT. Persistent pharmacokinetic challenges to pediatric drug development. Frontiers in Genetics. 5: 281. PMID 25221567 DOI: 10.3389/Fgene.2014.00281  0.612
2014 Carl SM, Herrera-Ruiz D, Bhardwaj RK, Gudmundsson O, Knipp GT. Peptide Transporters Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 67-90. DOI: 10.1002/9781118705308.ch5  0.774
2013 Roth WJ, Kissinger CB, McCain RR, Cooper BR, Marchant-Forde JN, Vreeman RC, Hannou S, Knipp GT. Assessment of juvenile pigs to serve as human pediatric surrogates for preclinical formulation pharmacokinetic testing. The Aaps Journal. 15: 763-74. PMID 23595360 DOI: 10.1208/S12248-013-9482-6  0.588
2012 Roth WJ, Lindley DJ, Carl SM, Knipp GT. The effects of intralaboratory modifications to media composition and cell source on the expression of pharmaceutically relevant transporters and metabolizing genes in the Caco-2 cell line. Journal of Pharmaceutical Sciences. 101: 3962-78. PMID 22786684 DOI: 10.1002/Jps.23241  0.775
2012 Lindley DJ, Roth WJ, Carl SM, Knipp GT. The effects of media on pharmaceutically relevant transporters in the human HT-29 adenocarcinoma cell line: does culture media need to be controlled? Journal of Pharmaceutical Sciences. 101: 1616-30. PMID 22213613 DOI: 10.1002/Jps.23036  0.771
2012 Carl SM, Lindley DJ, Das D, Couraud PO, Weksler BB, Romero I, Mowery SA, Knipp GT. Correction to “ABC and SLC Transporter Expression and Proton Oligopeptide Transporter (POT) Mediated Permeation across the Human Blood–Brain Barrier Cell Line, hCMEC/D3” Molecular Pharmaceutics. 9: 3606-3606. DOI: 10.1021/Mp300626K  0.787
2011 Lindley DJ, Carl SM, Mowery SA, Knipp GT. THE EVALUATION OF PEPTIDE/HISTIDINE TRANSPORTER 1 (PHT1) FUNCTION: UPTAKE KINETICS UTILIZING A COS-7 STABLY TRANSFECTED CELL LINE. Revista Mexicana De Ciencias Farmaceutica. 42: 57-65. PMID 23888104  0.796
2011 Lindley DJ, Carl SM, Herrera-Ruiz D, Pan LF, Karpes LB, Goole JME, Gudmundsson OS, Knipp GT. Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications. 291-308. DOI: 10.1002/9781118067598.ch18  0.682
2010 Carl SM, Lindley DJ, Das D, Couraud PO, Weksler BB, Romero I, Mowery SA, Knipp GT. ABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected]. Molecular Pharmaceutics. 7: 1057-68. PMID 20524699 DOI: 10.1021/Mp900178J  0.792
2010 Goole J, Lindley DJ, Roth W, Carl SM, Amighi K, Kauffmann JM, Knipp GT. The effects of excipients on transporter mediated absorption. International Journal of Pharmaceutics. 393: 17-31. PMID 20417699 DOI: 10.1016/J.Ijpharm.2010.04.019  0.764
2007 Mathis AS, Jin S, Friedman GS, Peng F, Carl SM, Knipp GT. The pharmacodynamic effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors. Journal of Pharmaceutical Sciences. 96: 209-22. PMID 17016853 DOI: 10.1002/Jps.20751  0.687
2007 Oliver E, Carl SM, Morris KR, Becker GW, Knipp GT. Regulatory Considerations in Approval on Follow-on Protein Drug Products Pharmaceutical Manufacturing Handbook: Production and Processes. 33-57. DOI: 10.1002/9780470259818.ch2  0.714
2007 Carl SM, Lindley DJ, Knipp GT, Morris KR, Oliver E, Becker GW, Arnold RD. Biotechnology-Derived Drug Product Development Pharmaceutical Manufacturing Handbook: Production and Processes. 1-32. DOI: 10.1002/9780470259818.ch1  0.747
2006 Bhardwaj RK, Herrera-Ruiz D, Eltoukhy N, Saad M, Knipp GT. The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 533-42. PMID 16289537 DOI: 10.1016/J.Ejps.2005.09.014  0.501
2006 Carl SM, Herrera-Ruiz D, Bhardwaj RK, Gudmundsson O, Knipp GT. Mammalian Oligopeptide Transporters Drug Transporters: Molecular Characterization and Role in Drug Disposition. 105-145. DOI: 10.1002/9780470140505.ch6  0.766
2005 Bhardwaj RK, Herrera-Ruiz D, Sinko PJ, Gudmundsson OS, Knipp G. Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells. The Journal of Pharmacology and Experimental Therapeutics. 314: 1093-100. PMID 15901802 DOI: 10.1124/Jpet.105.087148  0.534
2005 Xu Y, Cook TJ, Knipp GT. Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 84: 287-300. PMID 15647598 DOI: 10.1093/Toxsci/Kfi083  0.302
2005 Wang Q, Herrera-Ruiz D, Mathis AS, Cook TJ, Bhardwaj RK, Knipp GT. Expression of PPAR, RXR isoforms and fatty acid transporting proteins in the rat and human gastrointestinal tracts. Journal of Pharmaceutical Sciences. 94: 363-72. PMID 15614817 DOI: 10.1002/Jps.20264  0.376
2004 Wang Q, Bhardwaj RK, Herrera-Ruiz D, Hanna NN, Hanna IT, Gudmundsson OS, Buranachokpaisan T, Hidalgo IJ, Knipp GT. Expression of multiple drug resistance conferring proteins in normal Chinese and Caucasian small and large intestinal tissue samples. Molecular Pharmaceutics. 1: 447-54. PMID 16028356 DOI: 10.1021/Mp049942R  0.342
2004 Herrera-Ruiz D, Faria TN, Bhardwaj RK, Timoszyk J, Gudmundsson OS, Moench P, Wall DA, Smith RL, Knipp GT. A novel hPepT1 stably transfected cell line: establishing a correlation between expression and function. Molecular Pharmaceutics. 1: 136-44. PMID 15832510 DOI: 10.1021/Mp034011L  0.487
2003 Williams GC, Knipp GT, Sinko PJ. The effect of cell culture conditions on saquinavir transport through, and interactions with, MDCKII cells overexpressing hMDR1. Journal of Pharmaceutical Sciences. 92: 1957-67. PMID 14502536 DOI: 10.1002/Jps.10458  0.399
2003 Herrera-Ruiz D, Knipp GT. Current perspectives on established and putative mammalian oligopeptide transporters. Journal of Pharmaceutical Sciences. 92: 691-714. PMID 12661057 DOI: 10.1002/Jps.10303  0.5
2002 Zhang EY, Knipp GT, Ekins S, Swaan PW. Structural biology and function of solute transporters: implications for identifying and designing substrates. Drug Metabolism Reviews. 34: 709-50. PMID 12487148 DOI: 10.1081/Dmr-120015692  0.508
2002 Williams GC, Liu A, Knipp G, Sinko PJ. Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2). Antimicrobial Agents and Chemotherapy. 46: 3456-62. PMID 12384350 DOI: 10.1128/Aac.46.11.3456-3462.2002  0.471
2002 Wang Q, Fujii H, Knipp GT. Expression of PPAR and RXR isoforms in the developing rat and human term placentas Placenta. 23: 661-671. PMID 12361685 DOI: 10.1053/Plac.2002.0855  0.311
2002 Scott Mathis A, Friedman GS, Knipp GT. Do sex and ethnicity influence drug pharmacokinetics in solid organ transplantation? Graft. 5: 294-302. DOI: 10.1177/1522162802005005003  0.357
2001 Herrera-Ruiz D, Wang Q, Gudmundsson OS, Cook TJ, Smith RL, Faria TN, Knipp GT. Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues. Aaps Pharmsci. 3: E9. PMID 11741260 DOI: 10.1208/Ps030109  0.511
2001 Herrera-Ruiz D, Wang Q, Gudmundsson OS, Cook TJ, Smith RL, Faria TN, Knipp GT. Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues Aaps Pharmsci. 3.  0.417
2001 Herrera-Ruiz D, Wang Q, Gudmundsson OS, Cook TJ, Smith RL, Faria TN, Knipp GT. Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues Aaps Pharmsci. 3.  0.417
2000 Knipp GT, Liu B, Audus KL, Fujii H, Ono T, Soares MJ. Fatty acid transport regulatory proteins in the developing rat placenta and in trophoblast cell culture models Placenta. 21: 367-375. PMID 10833372 DOI: 10.1053/Plac.1999.0484  0.372
1999 Knipp GT, Audus KL, Soares MJ. Nutrient transport across the placenta Advanced Drug Delivery Reviews. 38: 41-58. DOI: 10.1016/S0169-409X(99)00005-8  0.447
1997 Sorensen M, Steenberg B, Knipp GT, Wang W, Steffansen B, Frokjaer S, Borchardt RT. The effect of β-turn structure on the permeation of peptides across monolayers of bovine brain microvessel endothelial cells Pharmaceutical Research. 14: 1341-1348. PMID 9358545 DOI: 10.1023/A:1012104301773  0.36
1997 Knipp GT, Vander Velde DG, Siahaan TJ, Borchardt RT. The effect of β-turn structure on the passive diffusion of peptides across caco-2 cell monolayers Pharmaceutical Research. 14: 1332-1340. PMID 9358544 DOI: 10.1023/A:1012152117703  0.36
1996 Pauletti GM, Gangwar S, Knipp GT, Nerurkar MM, Okumu FW, Tamura K, Siahaan TJ, Borchardt RT. Structural requirements for intestinal absorption of peptide drugs Journal of Controlled Release. 41: 3-17. DOI: 10.1016/0168-3659(96)01352-1  0.494
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