David Morilak - Publications

Affiliations: 
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Pharmacology, Neuroscience Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Paredes D, Morilak DA. Ventral Hippocampal Input to Infralimbic Cortex Is Necessary for the Therapeutic-Like Effects of Extinction in Stressed Rats. The International Journal of Neuropsychopharmacology. 26: 529-536. PMID 37480574 DOI: 10.1093/ijnp/pyad043  0.446
2023 Soteros BM, Tillmon H, Wollet M, General J, Chin H, Lee JB, Carreno FR, Morilak DA, Kim JH, Sia GM. Layer-specific microglia activation drives chronic stress-induced synapse loss. Biorxiv : the Preprint Server For Biology. PMID 37425856 DOI: 10.1101/2023.06.28.546889  0.312
2022 Paredes D, Knippenberg AR, Bulin SE, Keppler LJ, Morilak DA. Adjunct treatment with ketamine enhances the therapeutic effects of extinction learning after chronic unpredictable stress. Neurobiology of Stress. 19: 100468. PMID 35865972 DOI: 10.1016/j.ynstr.2022.100468  0.375
2021 Paredes D, Knippenberg AR, Morilak DA. Infralimbic BDNF signaling is necessary for the beneficial effects of extinction on set shifting in stressed rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34497360 DOI: 10.1038/s41386-021-01171-7  0.456
2020 Adler SM, Girotti M, Morilak DA. Optogenetically-induced long term depression in the rat orbitofrontal cortex ameliorates stress-induced reversal learning impairment. Neurobiology of Stress. 13: 100258. PMID 33344713 DOI: 10.1016/j.ynstr.2020.100258  0.421
2019 Bulin SE, Hohl KM, Paredes D, Silva JD, Morilak DA. Bidirectional optogenetically-induced plasticity of evoked responses in the rat medial prefrontal cortex can impair or enhance cognitive set-shifting. Eneuro. PMID 31852759 DOI: 10.1523/ENEURO.0363-19.2019  0.416
2019 Girotti M, Silva JD, George CM, Morilak DA. Ciliary neurotrophic factor signaling in the rat orbitofrontal cortex ameliorates stress-induced deficits in reversal learning. Neuropharmacology. 107791. PMID 31553898 DOI: 10.1016/j.neuropharm.2019.107791  0.409
2019 Paredes D, Morilak DA. A Rodent Model of Exposure Therapy: The Use of Fear Extinction as a Therapeutic Intervention for PTSD. Frontiers in Behavioral Neuroscience. 13: 46. PMID 30914932 DOI: 10.3389/fnbeh.2019.00046  0.328
2018 Fucich EA, Morilak DA. Shock-probe Defensive Burying Test to Measure Active versus Passive Coping Style in Response to an Aversive Stimulus in Rats. Bio-Protocol. 8. PMID 30271815 DOI: 10.21769/BioProtoc.2998  0.332
2018 Paredes D, Silva JD, Morilak DA. Ketamine corrects a deficit in reversal learning caused by chronic intermittent cold stress in female rats. The International Journal of Neuropsychopharmacology. PMID 30169648 DOI: 10.1093/ijnp/pyy080  0.377
2018 Fucich EA, Paredes D, Saunders MO, Morilak DA. Activity in the ventral medial prefrontal cortex is necessary for the therapeutic effects of extinction in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29335360 DOI: 10.1523/JNEUROSCI.0635-17.2017  0.405
2017 Girotti M, Adler SM, Bulin SE, Fucich EA, Paredes D, Morilak DA. Prefrontal cortex executive processes affected by stress in health and disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28690203 DOI: 10.1016/J.Pnpbp.2017.07.004  0.343
2017 Jett JD, Bulin SE, Hatherall LC, McCartney CM, Morilak DA. Deficits in cognitive flexibility induced by chronic unpredictable stress are associated with impaired glutamate neurotransmission in the rat medial prefrontal cortex. Neuroscience. PMID 28131625 DOI: 10.1016/J.Neuroscience.2017.01.017  0.367
2016 Hatherall L, Sánchez C, Morilak DA. Chronic vortioxetine treatment reduces exaggerated expression of conditioned fear memory and restores active coping behavior in chronically stressed rats. The International Journal of Neuropsychopharmacology. PMID 27927740 DOI: 10.1093/ijnp/pyw105  0.402
2016 Patton MS, Lodge DJ, Morilak DA, Girotti M. Ketamine Corrects Stress-Induced Cognitive Dysfunction through JAK2/STAT3 Signaling in the Orbitofrontal Cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27748739 DOI: 10.1038/npp.2016.236  0.64
2016 Fucich EA, Paredes D, Morilak DA. Therapeutic Effects of Extinction Learning as a Model of Exposure Therapy in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 3092-3102. PMID 27417516 DOI: 10.1038/npp.2016.127  0.393
2016 Fucich EA, Paredes D, Morilak DA. Therapeutic Effects of Extinction Learning as a Model of Exposure Therapy in Rats Neuropsychopharmacology. DOI: 10.1038/npp.2016.127  0.392
2015 Radley J, Morilak D, Viau V, Campeau S. Chronic stress and brain plasticity: Mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders. Neuroscience and Biobehavioral Reviews. PMID 26116544 DOI: 10.1016/J.Neubiorev.2015.06.018  0.331
2015 Jett JD, Boley AM, Girotti M, Shah A, Lodge DJ, Morilak DA. Antidepressant-like cognitive and behavioral effects of acute ketamine administration associated with plasticity in the ventral hippocampus to medial prefrontal cortex pathway. Psychopharmacology. PMID 25986748 DOI: 10.1007/S00213-015-3957-3  0.62
2015 Donegan JJ, Patton MS, Chavera TS, Berg KA, Morilak DA, Girotti M. Interleukin-6 attenuates serotonin 2a receptor signaling by activating the JAK-STAT pathway. Molecular Pharmacology. 87: 492-500. PMID 25549668 DOI: 10.1124/mol.114.096289  0.689
2014 Donegan JJ, Girotti M, Weinberg MS, Morilak DA. A novel role for brain interleukin-6: facilitation of cognitive flexibility in rat orbitofrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 953-62. PMID 24431453 DOI: 10.1523/JNEUROSCI.3968-13.2014  0.727
2014 Giuffrida A, Lodge D, Morilak D. THE CANNABINOID DICHOTOMY IN SCHIZOPHRENIA: FROM RISK FACTOR TO THERAPY Schizophrenia Research. 153: S46. DOI: 10.1016/S0920-9964(14)70150-1  0.476
2013 Bingham BC, Sheela Rani CS, Frazer A, Strong R, Morilak DA. Exogenous prenatal corticosterone exposure mimics the effects of prenatal stress on adult brain stress response systems and fear extinction behavior. Psychoneuroendocrinology. 38: 2746-57. PMID 23937971 DOI: 10.1016/J.Psyneuen.2013.07.003  0.355
2013 Naegeli KJ, O'Connor JA, Banerjee P, Morilak DA. Effects of milnacipran on cognitive flexibility following chronic stress in rats. European Journal of Pharmacology. 703: 62-6. PMID 23422875 DOI: 10.1016/j.ejphar.2013.02.006  0.398
2013 Girotti M, Donegan JJ, Morilak DA. Influence of hypothalamic IL-6/gp130 receptor signaling on the HPA axis response to chronic stress. Psychoneuroendocrinology. 38: 1158-69. PMID 23218517 DOI: 10.1016/j.psyneuen.2012.11.004  0.735
2013 Jett JD, Morilak DA. Too much of a good thing: blocking noradrenergic facilitation in medial prefrontal cortex prevents the detrimental effects of chronic stress on cognition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 585-95. PMID 23132268 DOI: 10.1038/npp.2012.216  0.379
2013 Morilak DA, Bingham B, Donegan JJ, Girotti M, Jett JD. Jekyll and Hyde: Noradrenergic Modulation in Acute and Chronic Stress Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 227-228. DOI: 10.1016/B978-0-12-800044-1.00203-8  0.698
2012 Roth MK, Bingham B, Shah A, Joshi A, Frazer A, Strong R, Morilak DA. Effects of chronic plus acute prolonged stress on measures of coping style, anxiety, and evoked HPA-axis reactivity. Neuropharmacology. 63: 1118-26. PMID 22842072 DOI: 10.1016/J.Neuropharm.2012.07.034  0.406
2012 Furr A, Lapiz-Bluhm MD, Morilak DA. 5-HT2A receptors in the orbitofrontal cortex facilitate reversal learning and contribute to the beneficial cognitive effects of chronic citalopram treatment in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1295-305. PMID 22008191 DOI: 10.1017/S1461145711001441  0.434
2012 Donegan J, Girotti M, Morilak D. 86. Orbitofrontal IL-6 enhances reversal learning in the rat Brain, Behavior, and Immunity. 26: S24. DOI: 10.1016/j.bbi.2012.07.110  0.677
2011 Campeau S, Liberzon I, Morilak D, Ressler K. Stress modulation of cognitive and affective processes. Stress (Amsterdam, Netherlands). 14: 503-19. PMID 21790481 DOI: 10.3109/10253890.2011.596864  0.333
2011 Green MK, Rani CS, Joshi A, Soto-Piña AE, Martinez PA, Frazer A, Strong R, Morilak DA. Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress. Neuroscience. 192: 438-51. PMID 21723377 DOI: 10.1016/J.Neuroscience.2011.06.041  0.387
2011 Girotti M, Donegan JJ, Morilak DA. Chronic intermittent cold stress sensitizes neuro-immune reactivity in the rat brain. Psychoneuroendocrinology. 36: 1164-74. PMID 21411230 DOI: 10.1016/j.psyneuen.2011.02.008  0.733
2010 Bondi CO, Jett JD, Morilak DA. Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by alpha1-adrenergic receptors in medial prefrontal cortex. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 913-23. PMID 20417676 DOI: 10.1016/J.Pnpbp.2010.04.016  0.707
2010 Danet M, Lapiz-Bluhm S, Morilak DA. A cognitive deficit induced in rats by chronic intermittent cold stress is reversed by chronic antidepressant treatment. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 997-1009. PMID 20149267 DOI: 10.1017/S1461145710000039  0.429
2009 Lapiz-Bluhm MD, Soto-Piña AE, Hensler JG, Morilak DA. Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats. Psychopharmacology. 202: 329-41. PMID 18587666 DOI: 10.1007/S00213-008-1224-6  0.36
2008 Lapiz-Bluhm MD, Bondi CO, Doyen J, Rodriguez GA, Bédard-Arana T, Morilak DA. Behavioural assays to model cognitive and affective dimensions of depression and anxiety in rats. Journal of Neuroendocrinology. 20: 1115-37. PMID 18673411 DOI: 10.1111/J.1365-2826.2008.01772.X  0.638
2008 Ma S, Mifflin SW, Cunningham JT, Morilak DA. Chronic intermittent hypoxia sensitizes acute hypothalamic-pituitary-adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stress Neuroscience. 154: 1639-1647. PMID 18554809 DOI: 10.1016/j.neuroscience.2008.04.068  0.373
2008 Zhao Z, Baros AM, Zhang HT, Lapiz MD, Bondi CO, Morilak DA, O'Donnell JM. Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3190-200. PMID 18418364 DOI: 10.1038/Npp.2008.45  0.628
2008 Bondi CO, Rodriguez G, Gould GG, Frazer A, Morilak DA. Chronic unpredictable stress induces a cognitive deficit and anxiety-like behavior in rats that is prevented by chronic antidepressant drug treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 320-31. PMID 17406647 DOI: 10.1038/Sj.Npp.1301410  0.694
2008 Morilak D, Bondi C, Lapiz-Bluhm M. S.20.05 Effects of chronic stress, monoamines and antidepressant drugs on cognitive function in prefrontal cortex European Neuropsychopharmacology. 18: S185. DOI: 10.1016/S0924-977X(08)70192-5  0.348
2007 Lapiz MD, Zhao Z, Bondi CO, O'Donnell JM, Morilak DA. Blockade of autoreceptor-mediated inhibition of norepinephrine release by atipamezole is maintained after chronic reuptake inhibition. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 827-33. PMID 17697440 DOI: 10.1017/S1461145707007651  0.629
2007 Bondi CO, Barrera G, Lapiz MD, Bedard T, Mahan A, Morilak DA. Noradrenergic facilitation of shock-probe defensive burying in lateral septum of rats, and modulation by chronic treatment with desipramine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 482-95. PMID 17188790 DOI: 10.1016/J.Pnpbp.2006.11.015  0.691
2007 Lapiz MD, Bondi CO, Morilak DA. Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1000-10. PMID 17077810 DOI: 10.1038/Sj.Npp.1301235  0.67
2007 Morilak DA. Norepinephrine and stress Brain Norepinephrine: Neurobiology and Therapeutics. 275-296. DOI: 10.1017/CBO9780511544156.010  0.325
2005 Morilak DA, Barrera G, Echevarria DJ, Garcia AS, Hernandez A, Ma S, Petre CO. Role of brain norepinephrine in the behavioral response to stress. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 1214-24. PMID 16226365 DOI: 10.1016/J.Pnpbp.2005.08.007  0.402
2005 Ma S, Morilak DA. Chronic intermittent cold stress sensitises the hypothalamic-pituitary-adrenal response to a novel acute stress by enhancing noradrenergic influence in the rat paraventricular nucleus Journal of Neuroendocrinology. 17: 761-769. PMID 16219005 DOI: 10.1111/j.1365-2826.2005.01372.x  0.39
2005 Echevarria DJ, Hernandez A, Diogenes A, Morilak DA. Administration of the galanin antagonist M40 into lateral septum attenuates shock probe defensive burying behavior in rats. Neuropeptides. 39: 445-51. PMID 16084587 DOI: 10.1016/J.Npep.2005.06.004  0.315
2005 Ma S, Morilak DA. Norepinephrine release in medial amygdala facilitates activation of the hypothalamic-pituitary-adrenal axis in response to acute immobilisation stress Journal of Neuroendocrinology. 17: 22-28. PMID 15720472 DOI: 10.1111/j.1365-2826.2005.01279.x  0.34
2004 Ma S, Morilak DA. Induction of Fos expression by acute immobilization stress is reduced in locus coeruleus and medial amygdala of Wistar-Kyoto rats compared to Sprague-Dawley rats Neuroscience. 124: 963-972. PMID 15026136 DOI: 10.1016/j.neuroscience.2003.12.028  0.36
2003 Morilak DA, Cecchi M, Khoshbouei H. Interactions of norepinephrine and galanin in the central amygdala and lateral bed nucleus of the stria terminalis modulate the behavioral response to acute stress. Life Sciences. 73: 715-26. PMID 12801593 DOI: 10.1016/S0024-3205(03)00392-8  0.331
2003 Pardon MC, Ma S, Morilak DA. Chronic cold stress sensitizes brain noradrenergic reactivity and noradrenergic facilitation of the HPA stress response in Wistar Kyoto rats. Brain Research. 971: 55-65. PMID 12691837 DOI: 10.1016/S0006-8993(03)02355-2  0.379
2002 Cecchi M, Khoshbouei H, Morilak DA. Modulatory effects of norepinephrine, acting on alpha 1 receptors in the central nucleus of the amygdala, on behavioral and neuroendocrine responses to acute immobilization stress. Neuropharmacology. 43: 1139-47. PMID 12504920 DOI: 10.1016/S0028-3908(02)00292-7  0.332
2002 Pardon MC, Gould GG, Garcia A, Phillips L, Cook MC, Miller SA, Mason PA, Morilak DA. Stress reactivity of the brain noradrenergic system in three rat strains differing in their neuroendocrine and behavioral responses to stress: implications for susceptibility to stress-related neuropsychiatric disorders. Neuroscience. 115: 229-42. PMID 12401336 DOI: 10.1016/S0306-4522(02)00364-0  0.358
2002 Khoshbouei H, Cecchi M, Morilak DA. Modulatory effects of galanin in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 25-34. PMID 12062904 DOI: 10.1016/S0893-133X(01)00424-9  0.354
2002 Cecchi M, Khoshbouei H, Javors M, Morilak DA. Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress. Neuroscience. 112: 13-21. PMID 12044468 DOI: 10.1016/S0306-4522(02)00062-3  0.342
2002 Khoshbouei H, Cecchi M, Dove S, Javors M, Morilak DA. Behavioral reactivity to stress: amplification of stress-induced noradrenergic activation elicits a galanin-mediated anxiolytic effect in central amygdala. Pharmacology, Biochemistry, and Behavior. 71: 407-17. PMID 11830175 DOI: 10.1016/S0091-3057(01)00683-9  0.343
2000 Sands SA, Strong R, Corbitt J, Morilak DA. Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wistar and Wistar-Kyoto rats Molecular Brain Research. 75: 1-7. PMID 10648882 DOI: 10.1016/S0169-328X(99)00255-7  0.317
2000 Sands SA, Guerra V, Morilak DA. Changes in tyrosine hydroxylase mRNA expression in the rat locus coeruleus following acute or chronic treatment with valproic acid Neuropsychopharmacology. 22: 27-35. PMID 10633488 DOI: 10.1016/S0893-133X(99)00072-X  0.318
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