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Christopher L. Brett, Ph.D. M.D. - Publications

Affiliations: 
Biology Concordia University (Canada), Montreal, QC, Canada 
Area:
Ion transport, pH regulation, endocytosis, membrane fusion, synaptic plasticity
Website:
http://www.brettlab.org/
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Golden CK, Kazmirchuk TDD, McNally EK, El Eissawi M, Gokbayrak ZD, Richard JD, Brett CL. A two-tiered system for selective receptor and transporter protein degradation. Plos Genetics. 18: e1010446. PMID 36215320 DOI: 10.1371/journal.pgen.1010446  0.318
2019 Mattie S, Kazmirchuk T, Mui J, Vali H, Brett CL. Visualization of SNARE-Mediated Organelle Membrane Hemifusion by Electron Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1860: 361-377. PMID 30317518 DOI: 10.1007/978-1-4939-8760-3_24  0.355
2019 Karim MA, Samyn DR, Brett CL. A Cell-Free Content Mixing Assay for SNARE-Mediated Multivesicular Body-Vacuole Membrane Fusion. Methods in Molecular Biology (Clifton, N.J.). 1860: 289-301. PMID 30317513 DOI: 10.1007/978-1-4939-8760-3_19  0.416
2018 McNally EK, Brett CL. The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation. Nature Communications. 9: 5358. PMID 30560896 DOI: 10.1038/S41467-018-07734-5  0.444
2018 Karim MA, McNally EK, Samyn DR, Mattie S, Brett CL. Rab-Effector-Kinase Interplay Modulates Intralumenal Fragment Formation during Vacuole Fusion. Developmental Cell. 47: 80-97.e6. PMID 30269949 DOI: 10.1016/J.Devcel.2018.09.002  0.47
2017 Karim MA, Brett CL. The Na+(K+)/H+ exchanger Nhx1 controls multivesicular body-vacuolar lysosome fusion. Molecular Biology of the Cell. PMID 29212874 DOI: 10.1091/Mbc.E17-08-0496  0.376
2017 Karim MA, Samyn DR, Mattie S, Brett CL. Distinct features of multivesicular body-lysosome fusion revealed by a new cell-free content-mixing assay. Traffic (Copenhagen, Denmark). PMID 29135058 DOI: 10.1111/Tra.12543  0.432
2016 McNally EK, Karim MA, Brett CL. Selective Lysosomal Transporter Degradation by Organelle Membrane Fusion. Developmental Cell. PMID 28017618 DOI: 10.1016/J.Devcel.2016.11.024  0.485
2016 McNally SM, Karim EK, Vali MA, Brett H, Brett CL. How and Why Intralumenal Membrane Fragments Form During Vacuolar Lysosome Fusion. Molecular Biology of the Cell. PMID 27881666 DOI: 10.1091/Mbc.E15-11-0759  0.308
2013 Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, et al. Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. American Journal of Human Genetics. 93: 181-90. PMID 23830518 DOI: 10.1016/J.Ajhg.2013.05.028  0.412
2012 Lockshon D, Olsen CP, Brett CL, Chertov A, Merz AJ, Lorenz DA, Van Gilst MR, Kennedy BK. Rho signaling participates in membrane fluidity homeostasis. Plos One. 7: e45049. PMID 23071506 DOI: 10.1371/Journal.Pone.0045049  0.655
2012 Lo SY, Brett CL, Plemel RL, Vignali M, Fields S, Gonen T, Merz AJ. Intrinsic tethering activity of endosomal Rab proteins. Nature Structural & Molecular Biology. 19: 40-7. PMID 22157956 DOI: 10.1038/Nsmb.2162  0.737
2011 Kallay LM, Brett CL, Tukaye DN, Wemmer MA, Chyou A, Odorizzi G, Rao R. Endosomal Na+ (K+)/H+ exchanger Nhx1/Vps44 functions independently and downstream of multivesicular body formation. The Journal of Biological Chemistry. 286: 44067-77. PMID 21998311 DOI: 10.1074/Jbc.M111.282319  0.601
2011 Brett CL, Kallay L, Hua Z, Green R, Chyou A, Zhang Y, Graham TR, Donowitz M, Rao R. Genome-wide analysis reveals the vacuolar pH-stat of Saccharomyces cerevisiae. Plos One. 6: e17619. PMID 21423800 DOI: 10.1371/Journal.Pone.0017619  0.611
2011 Plemel RL, Lobingier BT, Brett CL, Angers CG, Nickerson DP, Paulsel A, Sprague D, Merz AJ. Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic. Molecular Biology of the Cell. 22: 1353-63. PMID 21325627 DOI: 10.1091/Mbc.E10-03-0260  0.522
2011 Brett CL, Plemel RL, Lobingier BT, Vignali M, Fields S, Merz AJ. Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase Journal of Cell Biology. 195: 1061. DOI: 10.1083/jcb.2008010011956c  0.764
2009 Nickerson DP, Brett CL, Merz AJ. Vps-C complexes: gatekeepers of endolysosomal traffic. Current Opinion in Cell Biology. 21: 543-51. PMID 19577915 DOI: 10.1016/J.Ceb.2009.05.007  0.794
2008 Brett CL, Plemel RL, Lobingier BT, Lobinger BT, Vignali M, Fields S, Merz AJ. Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. The Journal of Cell Biology. 182: 1141-51. PMID 18809726 DOI: 10.1083/Jcb.200801001  0.783
2008 Brett CL, Merz AJ. Osmotic regulation of Rab-mediated organelle docking. Current Biology : Cb. 18: 1072-7. PMID 18619842 DOI: 10.1016/J.Cub.2008.06.050  0.627
2006 Hill JK, Brett CL, Chyou A, Kallay LM, Sakaguchi M, Rao R, Gillespie PG. Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9944-55. PMID 17005858 DOI: 10.1523/Jneurosci.2990-06.2006  0.492
2006 Mukherjee S, Kallay L, Brett CL, Rao R. Mutational analysis of the intramembranous H10 loop of yeast Nhx1 reveals a critical role in ion homoeostasis and vesicle trafficking. The Biochemical Journal. 398: 97-105. PMID 16671892 DOI: 10.1042/Bj20060388  0.542
2006 Brett CL, Donowitz M, Rao R. Does the proteome encode organellar pH? Febs Letters. 580: 717-9. PMID 16413548 DOI: 10.1016/J.Febslet.2005.12.103  0.601
2005 Donowitz M, Cha B, Zachos NC, Brett CL, Sharma A, Tse CM, Li X. NHERF family and NHE3 regulation. The Journal of Physiology. 567: 3-11. PMID 15905209 DOI: 10.1113/Jphysiol.2005.090399  0.606
2005 Brett CL, Donowitz M, Rao R. Evolutionary origins of eukaryotic sodium/proton exchangers. American Journal of Physiology. Cell Physiology. 288: C223-39. PMID 15643048 DOI: 10.1152/Ajpcell.00360.2004  0.621
2005 Brett CL, Tukaye DN, Mukherjee S, Rao R. The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking. Molecular Biology of the Cell. 16: 1396-405. PMID 15635088 DOI: 10.1091/Mbc.E04-11-0999  0.535
2004 Ali R, Brett CL, Mukherjee S, Rao R. Inhibition of sodium/proton exchange by a Rab-GTPase-activating protein regulates endosomal traffic in yeast. The Journal of Biological Chemistry. 279: 4498-506. PMID 14610088 DOI: 10.1074/Jbc.M307446200  0.615
2002 Brett CL, Kelly T, Sheldon C, Church J. Regulation of Cl--HCO3- exchangers by cAMP-dependent protein kinase in adult rat hippocampal CA1 neurons. The Journal of Physiology. 545: 837-53. PMID 12482890 DOI: 10.1113/Jphysiol.2002.027235  0.681
2002 Brett CL, Wei Y, Donowitz M, Rao R. Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria. American Journal of Physiology. Cell Physiology. 282: C1031-41. PMID 11940519 DOI: 10.1152/Ajpcell.00420.2001  0.629
1999 Diarra A, Sheldon C, Brett CL, Baimbridge KG, Church J. Anoxia-evoked intracellular pH and Ca2+ concentration changes in cultured postnatal rat hippocampal neurons. Neuroscience. 93: 1003-16. PMID 10473265 DOI: 10.1016/S0306-4522(99)00230-4  0.679
1998 Smith GA, Brett CL, Church J. Effects of noradrenaline on intracellular pH in acutely dissociated adult rat hippocampal CA1 neurones. The Journal of Physiology. 512: 487-505. PMID 9763638 DOI: 10.1111/J.1469-7793.1998.487Be.X  0.594
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