| Year |
Citation |
Score |
| 2023 |
Irani S, Tan W, Li Q, Toy W, Jones C, Gadiya M, Marra A, Katzenellenbogen JA, Carlson KE, Katzenellenbogen BS, Karimi M, Segu Rajappachetty R, Del Priore IS, Reis-Filho JS, Shen Y, et al. Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation. The Journal of Clinical Investigation. PMID 37883178 DOI: 10.1172/JCI163242 |
0.362 |
|
| 2021 |
Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, ... ... Katzenellenbogen JA, et al. Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34452998 DOI: 10.1073/pnas.2101657118 |
0.403 |
|
| 2021 |
Mayne CG, Toy W, Carlson KE, Bhatt T, Fanning SW, Greene GL, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA, Tajkhorshid E. Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular Cancer Research : McR. PMID 34021071 DOI: 10.1158/1541-7786.MCR-20-1017 |
0.728 |
|
| 2020 |
Li Y, Coons LA, Houtman R, Carlson KE, Martin TA, Mayne CG, Melchers D, Jefferson TB, Ramsey JT, Katzenellenbogen JA, Korach KS. A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment. Science Signaling. 13. PMID 32963012 DOI: 10.1126/scisignal.aaw4653 |
0.722 |
|
| 2020 |
Dey P, Wang A, Ziegler Y, Kim SH, El-Ashry D, Katzenellenbogen JA, Katzenellenbogen BS. Suppression of Tumor Growth, Metastasis, and Signaling Pathways by Reducing FOXM1 Activity in Triple Negative Breast Cancer. Cancers. 12. PMID 32961773 DOI: 10.3390/Cancers12092677 |
0.3 |
|
| 2020 |
Katzenellenbogen JA. PET Imaging Agents (FES, FFNP, and FDHT) for Estrogen, Androgen, and Progesterone Receptors to Improve Management of Breast and Prostate Cancers by Functional Imaging. Cancers. 12. PMID 32718075 DOI: 10.3390/Cancers12082020 |
0.405 |
|
| 2020 |
Laws MJ, Ziegler Y, Shahoei SH, Dey P, Kim SH, Yasuda M, Park BH, Nettles KW, Katzenellenbogen JA, Nelson ER, Katzenellenbogen BS. Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors. Breast Cancer Research and Treatment. PMID 32277377 DOI: 10.1007/S10549-020-05629-Y |
0.379 |
|
| 2020 |
Katzenellenbogen JA. The quest for improving the management of breast cancer by functional imaging: The discovery and development of 16α-[F]fluoroestradiol (FES), a PET radiotracer for the estrogen receptor, a historical review. Nuclear Medicine and Biology. PMID 32229068 DOI: 10.1016/J.Nucmedbio.2020.02.007 |
0.399 |
|
| 2020 |
Brakta S, Chorich LP, Kim HG, Coons LA, Katzenellenbogen JA, Hall JE, Kenneth SK, Layman LC. Long-Term Follow Up and Treatment of a Female with Complete Estrogen Insensitivity. The Journal of Clinical Endocrinology and Metabolism. PMID 32152632 DOI: 10.1210/Clinem/Dgaa106 |
0.314 |
|
| 2020 |
Nwachukwu J, Min J, Srinivasan SK, Rangarajan E, Guillen VS, Ziegler Y, Carlson K, Hou Y, Kim SH, Izard T, Houtman R, Katzenellenbogen BS, Nettles KW, Katzenellenbogen JA. OR12-07 Full Antagonism of Breast Cancer Cell Proliferation Can Result from Many Ligand-Induced Conformational Distortions of the Estrogen Receptor Ligand Binding Domain Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.249 |
0.516 |
|
| 2020 |
Katzenellenbogen JA, Min J, Srinivasan S, Rangarajan ES, Nwachukwu JC, Guillen VS, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Izard T, Houtman R, Nettles KW, Katzenellenbogen BS. Abstract P6-04-10: Combining direct and indirect modes of antiestrogen ligand antagonism of estrogen receptor activity in breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-04-10 |
0.473 |
|
| 2020 |
Katzenellenbogen BS, Ziegler Y, Laws MJ, Guillen VS, Kim S, Dey P, Smith BP, Gong P, Bindman N, Zhao Y, Carlson K, Yasuda MA, Singh D, Li Z, El-Ashry D, ... ... Katzenellenbogen JA, et al. Abstract P5-05-05: Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P5-05-05 |
0.305 |
|
| 2019 |
Lo YC, Cormier O, Liu T, Nettles KW, Katzenellenbogen JA, Stearns T, Altman RB. Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site. Nature Communications. 10: 1033. PMID 30833575 DOI: 10.1038/S41467-019-08965-W |
0.451 |
|
| 2019 |
Karim H, Kim SH, Lauderdale K, Lapato AS, Atkinson K, Yasui N, Yamate-Morgan H, Sekyi M, Katzenellenbogen JA, Tiwari-Woodruff SK. Analogues of ERβ ligand chloroindazole exert immunomodulatory and remyelinating effects in a mouse model of multiple sclerosis. Scientific Reports. 9: 503. PMID 30679747 DOI: 10.1038/S41598-018-37420-X |
0.329 |
|
| 2019 |
Skaddan MB, Wüst FR, Katzenellenbogen JA. Synthesis and Binding Affinities of Novel Re-Containing 7alpha-Substituted Estradiol Complexes: Models for Breast Cancer Imaging Agents. The Journal of Organic Chemistry. 64: 8108-8121. PMID 11674724 DOI: 10.1021/Jo990641G |
0.799 |
|
| 2019 |
Hom RK, Chi DY, Katzenellenbogen JA. Heterodimeric Bis(amino thiol) Complexes of Oxorhenium(V) That Mimic the Structure of Steroid Hormones. Synthesis and Stereochemical Issues. The Journal of Organic Chemistry. 61: 2624-2631. PMID 11667091 DOI: 10.1021/Jo951995K |
0.576 |
|
| 2018 |
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Katzenellenbogen JA, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/Elife.37161 |
0.735 |
|
| 2018 |
Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/Acschembio.8B00877 |
0.812 |
|
| 2018 |
Selvaraj UM, Zuurbier K, Whoolery C, Plautz EJ, Chambliss KL, Kong X, Zhang S, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW, Stowe AM. Selective Non-nuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice. Endocrinology. PMID 30256928 DOI: 10.1210/En.2018-00600 |
0.316 |
|
| 2018 |
Zhou D, Xu J, Mpoy C, Chu W, Kim SH, Li H, Rogers BE, Katzenellenbogen JA. Preliminary evaluation of a novel F-labeled PARP-1 ligand for PET imaging of PARP-1 expression in prostate cancer. Nuclear Medicine and Biology. 66: 26-31. PMID 30195072 DOI: 10.1016/J.Nucmedbio.2018.08.003 |
0.313 |
|
| 2018 |
Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 30185950 DOI: 10.1038/S41568-018-0053-0 |
0.688 |
|
| 2018 |
Bononi G, Granchi C, Lapillo M, Giannotti M, Nieri D, Fortunato S, Boustani ME, Caligiuri I, Poli G, Carlson KE, Kim SH, Macchia M, Martinelli A, Rizzolio F, Chicca A, ... Katzenellenbogen JA, et al. Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors. European Journal of Medicinal Chemistry. 157: 817-836. PMID 30144699 DOI: 10.1016/J.Ejmech.2018.08.038 |
0.309 |
|
| 2018 |
Wang L, Guillen VS, Sharma N, Flessa K, Min J, Carlson KE, Toy W, Braqi S, Katzenellenbogen BS, Katzenellenbogen JA, Chandarlapaty S, Sharma A. New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons. Acs Medicinal Chemistry Letters. 9: 803-808. PMID 30128071 DOI: 10.1021/Acsmedchemlett.8B00106 |
0.805 |
|
| 2018 |
Pollock JA, Sharma N, Ippagunta SK, Redecke V, Häcker H, Katzenellenbogen J. Triaryl Pyrazole Toll-Like Receptor Signaling Inhibitors: Structure-Activity Relationships Governing Pan- and Selective Signaling Inhibitors. Chemmedchem. PMID 30117269 DOI: 10.1002/Cmdc.201800417 |
0.638 |
|
| 2018 |
Ippagunta SK, Pollock JA, Sharma N, Lin W, Chen T, Tawaratsumida K, High AA, Min J, Chen Y, Guy RK, Redecke V, Katzenellenbogen JA, Häcker H. Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins. Science Signaling. 11. PMID 30108181 DOI: 10.1126/Scisignal.Aaq1077 |
0.658 |
|
| 2018 |
Guivarc'h E, Buscato M, Guihot AL, Favre J, Vessières E, Grimaud L, Wakim J, Melhem NJ, Zahreddine R, Adlanmerini M, Loufrani L, Knauf C, Katzenellenbogen JA, Katzenellenbogen BS, Foidart JM, et al. Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety. Journal of the American Heart Association. 7. PMID 29959137 DOI: 10.1161/Jaha.118.008950 |
0.392 |
|
| 2018 |
Karim H, Kim SH, Lapato AS, Yasui N, Katzenellenbogen JA, Tiwari-Woodruff SK. Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844175 DOI: 10.1073/Pnas.1721732115 |
0.357 |
|
| 2018 |
Amzaleg Y, Ji J, Kittivanichkul D, E Törnqvist A, Windahl S, Sabag E, Khalid AB, Sternberg H, West M, Katzenellenbogen JA, Krum SA, Chimge NO, Schones DE, Gabet Y, Ohlsson C, et al. Estrogens and selective estrogen receptor modulators differentially antagonize Runx2 in ST2 mesenchymal progenitor cells. The Journal of Steroid Biochemistry and Molecular Biology. PMID 29751107 DOI: 10.1016/J.Jsbmb.2018.05.002 |
0.331 |
|
| 2018 |
Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 29662238 DOI: 10.1038/S41568-018-0001-Z |
0.757 |
|
| 2018 |
Vinel A, Coudert AE, Buscato M, Valera MC, Agnès O, Katzenellenbogen JA, Katzenellenbogen BS, Berdal A, Babajko S, Arnal JF, Fontaine C. Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: implications for ERα modulation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29624728 DOI: 10.1002/Jbmr.3434 |
0.304 |
|
| 2018 |
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Katzenellenbogen JA, et al. Author response: The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells Elife. DOI: 10.7554/Elife.37161.024 |
0.65 |
|
| 2018 |
Laws MJ, Kim SH, Min J, Zhao Y, Ziegler Y, Chu D, Park BH, Katzenellenbogen JA, Katzenellenbogen BS. Abstract 946: Suppression of breast cancer metastasis and extension of host animal survival by a new adamantyl antiestrogen, K-07, in a preclinical breast cancer metastasis model driven by constitutively active mutant estrogen receptors Cancer Research. 78: 946-946. DOI: 10.1158/1538-7445.Am2018-946 |
0.363 |
|
| 2018 |
Laws MJ, Kim SH, Ziegler Y, Bindman N, Gong P, Guillen VS, Yasuda M, Singh D, El-Ashry D, Katzenellenbogen JA, Katzenellenbogen BS. Abstract 1955: Suppression of hormone receptor-positive and triple-negative breast cancers by new inhibitors of the transcription factor FOXM1 Cancer Research. 78: 1955-1955. DOI: 10.1158/1538-7445.Am2018-1955 |
0.381 |
|
| 2017 |
Katzenellenbogen BS, Zhao Y, Laws MJ, Sanabria Guillen V, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA. Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors. Cancer Research. PMID 28904064 DOI: 10.1158/0008-5472.Can-17-1265 |
0.569 |
|
| 2017 |
Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/Acs.Jmedchem.7B00585 |
0.781 |
|
| 2017 |
Arnal JF, Lenfant F, Metivier R, Flouriot G, Henrion D, Adlanmerini M, Fontaine C, Gourdy P, Chambon P, Katzenellenbogen B, Katzenellenbogen J. Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications. Physiological Reviews. 97: 1045-1087. PMID 28539435 DOI: 10.1152/Physrev.00024.2016 |
0.393 |
|
| 2017 |
Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691. PMID 28514424 DOI: 10.1038/Nchembio0617-691C |
0.36 |
|
| 2017 |
Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691. PMID 28514419 DOI: 10.1038/nchembio0617-691b |
0.386 |
|
| 2017 |
Zhou D, Kim SH, Chu W, Voller T, Katzenellenbogen JA. Evaluation of Aromatic Radiobromination by Nucleophilic Substitution using Diaryliodonium Salt Precursors. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 28512784 DOI: 10.1002/Jlcr.3519 |
0.303 |
|
| 2017 |
Menazza S, Sun J, Appachi S, Chambliss KL, Kim SH, Aponte A, Khan S, Katzenellenbogen JA, Katzenellenbogen BS, Shaul PW, Murphy E. Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice. Journal of Molecular and Cellular Cardiology. PMID 28457941 DOI: 10.1016/J.Yjmcc.2017.04.004 |
0.403 |
|
| 2017 |
Madak-Erdogan Z, Charn TH, Jiang Y, Liu ET, Katzenellenbogen JA, Katzenellenbogen BS. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 13: 929. PMID 28442489 DOI: 10.15252/Msb.20177595 |
0.791 |
|
| 2017 |
Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, et al. Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Molecular Cell. 65: 1122-1135.e5. PMID 28306507 DOI: 10.1016/J.Molcel.2017.02.008 |
0.337 |
|
| 2017 |
Christenson JL, Butterfield KT, Spoelstra NS, Norris JD, Josan JS, Pollock JA, McDonnell DP, Katzenellenbogen BS, Katzenellenbogen JA, Richer JK. MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression. Hormones & Cancer. PMID 28194662 DOI: 10.1007/S12672-017-0285-6 |
0.673 |
|
| 2017 |
Josan J, Pokludova K, Devi S, Srinivasan S, Katzenellenbogen J, Nettles K. Abstract P2-08-07: Anti-proliferative and anti-inflammatory estrogen receptor agents for treatment of endocrine-resistant breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P2-08-07 |
0.349 |
|
| 2017 |
Toy W, Carlson KE, Martin TA, Mayne CG, Fanning SW, Razavi P, Baselga J, Shen Y, Greene G, Katzenellenbogen B, Katzenellenbogen J, Chandarlapaty S. Abstract 999: ESR1 mutations activate and confer hormone resistance via distinct mechanisms Endocrinology. 77: 999-999. DOI: 10.1158/1538-7445.Am2017-999 |
0.633 |
|
| 2017 |
Sun J, Menazza S, Appachi S, Chambliss K, Kim S, Aponte A, Khan S, Katzenellenbogen J, Katzenellenbogen B, Shaul P, Murphy E. Membrane delimited estrogen receptor activation protects heart against ischemic-reperfusion injury in mice with cardiac but not endothelial specific ablation of ERα Journal of Molecular and Cellular Cardiology. 112: 139-140. DOI: 10.1016/J.Yjmcc.2017.07.030 |
0.3 |
|
| 2016 |
Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao XQ, Grant BJ, Kojetin DJ, Elemento O, Katzenellenbogen JA, Nettles KW. Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chemical Biology. PMID 28042045 DOI: 10.1016/J.Chembiol.2016.11.014 |
0.425 |
|
| 2016 |
Sharma N, Carlson KE, Nwachukwu JC, Srinivasan S, Sharma A, Nettles KW, Katzenellenbogen JA. Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. Acs Chemical Biology. PMID 28032978 DOI: 10.1021/Acschembio.6B00918 |
0.646 |
|
| 2016 |
Zhang S, Wang Z, Hu Z, Li C, Tang C, Carlson KE, Luo J, Dong C, Katzenellenbogen JA, Huang J, Zhou H. Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands. Chemmedchem. PMID 27976818 DOI: 10.1002/Cmdc.201600593 |
0.541 |
|
| 2016 |
Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. PMID 27870835 DOI: 10.1038/Nchembio.2236 |
0.478 |
|
| 2016 |
Chambliss KL, Barrera J, Umetani M, Umetani J, Kim SH, Madak-Erdogan Z, Huang L, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW. Non-Nuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. Endocrinology. en20151629. PMID 27552247 DOI: 10.1210/En.2015-1629 |
0.366 |
|
| 2016 |
Gong P, Madak-Erdogan Z, Flaws JA, Shapiro DJ, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells. Molecular and Cellular Endocrinology. PMID 27543265 DOI: 10.1016/J.Mce.2016.08.025 |
0.495 |
|
| 2016 |
Pollock JA, Wardell SE, Parent AA, Stagg DB, Ellison SJ, Alley HM, Chao CA, Lawrence SA, Stice JP, Spasojevic I, Baker JG, Kim SH, McDonnell DP, Katzenellenbogen JA, Norris JD. Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer. Nature Chemical Biology. PMID 27501397 DOI: 10.1038/Nchembio.2131 |
0.805 |
|
| 2016 |
Madak-Erdogan Z, Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen BS. Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling. 9: ra53. PMID 27221711 DOI: 10.1126/Scisignal.Aad8170 |
0.724 |
|
| 2016 |
Katzenellenbogen BS, Katzenellenbogen JA, Madak-Erdogan Z, VanHook AM. Science Signaling podcast for 24 May 2016: Designer estrogens. Science Signaling. 9: pc12. PMID 27221709 DOI: 10.1126/Scisignal.Aag1040 |
0.332 |
|
| 2016 |
Granchi C, Lapillo M, Spena CR, Rizzolio F, Tuccinardi T, Martin TA, Carlson KE, Katzenellenbogen JA, Minutolo F. Cyclic Ketoximes as Estrogen Receptor β Selective Agonists. Chemmedchem. PMID 27135651 DOI: 10.1002/Cmdc.201600140 |
0.511 |
|
| 2016 |
Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F. Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metabolism. PMID 27133133 DOI: 10.1016/J.Cmet.2016.03.015 |
0.329 |
|
| 2016 |
Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, et al. Predictive features of ligand-specific signaling through the estrogen receptor. Molecular Systems Biology. 12: 864. PMID 27107013 DOI: 10.15252/Msb.20156701 |
0.465 |
|
| 2016 |
Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, et al. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife. 5. PMID 26836308 DOI: 10.7554/Elife.12792 |
0.721 |
|
| 2016 |
Fowler AM, Clark AS, Katzenellenbogen JA, Linden HM, Dehdashti F. Imaging Diagnostic and Therapeutic Targets: Steroid Receptors in Breast Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 57: 75S-80S. PMID 26834106 DOI: 10.2967/Jnumed.115.157933 |
0.452 |
|
| 2016 |
Farman H, Wu J, Gustafsson K, Windahl S, Kim S, Katzenellenbogen J, Ohlsson C, Lagerquist M. Extranuclear effects of estrogen on cortical bone in males is dependent on estrogen receptor A activation function-1 Bone Abstracts. DOI: 10.1530/Boneabs.5.Oc6.4 |
0.382 |
|
| 2016 |
Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, et al. Predictive features of ligand-specific signaling through the estrogen receptor Molecular Systems Biology. 12. DOI: 10.15252/msb.20156701 |
0.358 |
|
| 2016 |
Garner F, Brown J, Katzenellenbogen J, Lyttle C, Hattersley G. Abstract P3-05-07: RAD1901, a novel oral, selective estrogen receptor degrader (SERD) with single agent efficacy in an ER+ primary patent derived ESR1 mutant xenograft model Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-05-07 |
0.437 |
|
| 2016 |
Fanning SW, Dharmarajan V, Mayne CG, Toy W, Carlson KE, Martin TA, Nowak J, Nwachukwu J, Hosfield DJ, Tajkhorshid E, Chandarlapaty S, Griffin P, Shen Y, Katzenellenbogen JA, Greene GL. Abstract 4854: Bazedoxifene inhibits ESR1 somatic mutants with improved potency compared to tamoxifene and raloxifene Cancer Research. 76: 4854-4854. DOI: 10.1158/1538-7445.Am2016-4854 |
0.717 |
|
| 2015 |
Xiong R, Patel HK, Gutgesell LM, Zhao J, Delgado-Rivera L, Pham TN, Zhao H, Carlson KE, Martin TA, Katzenellenbogen JA, Moore TW, Tonetti D, Thatcher GR. Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer. Journal of Medicinal Chemistry. PMID 26681208 DOI: 10.1021/Acs.Jmedchem.5B01276 |
0.702 |
|
| 2015 |
Zhao Y, Chen Y, Kuang Y, Bagchi MK, Taylor RN, Katzenellenbogen JA, Katzenellenbogen BS. Multiple Beneficial Roles of Repressor of Estrogen Receptor Activity (REA) in Suppressing the Progression of Endometriosis. Endocrinology. en20151324. PMID 26653759 DOI: 10.1210/En.2015-1324 |
0.318 |
|
| 2015 |
Boonmuen N, Gong P, Ali Z, Chittiboyina AG, Khan I, Doerge DR, Helferich WG, Carlson KE, Martin T, Piyachaturawat P, Katzenellenbogen JA, Katzenellenbogen BS. Licorice Root Components in Dietary Supplements are Selective Estrogen Receptor Modulators with a Spectrum of Estrogenic and Anti-Estrogenic Activities. Steroids. PMID 26631549 DOI: 10.1016/J.Steroids.2015.11.006 |
0.618 |
|
| 2015 |
Yasui N, Mayne CG, Katzenellenbogen JA. Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling. Organic Letters. PMID 26536250 DOI: 10.1021/Acs.Orglett.5B02640 |
0.6 |
|
| 2015 |
Pollock JA, Kim SH, Katzenellenbogen JA. Imidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles. Tetrahedron Letters. 56: 6097-6099. PMID 26516292 DOI: 10.1016/J.Tetlet.2015.09.076 |
0.605 |
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| 2015 |
Pisani SL, Neese SL, Katzenellenbogen JA, Schantz SL, Korol DL. ESTROGEN RECEPTOR SELECTIVE AGONISTS MODULATE LEARNING IN FEMALE RATS IN A DOSE- AND TASK-SPECIFIC MANNER. Endocrinology. en20151616. PMID 26465198 DOI: 10.1210/En.2015-1616 |
0.348 |
|
| 2015 |
Smirnova NF, Fontaine C, Buscato M, Lupieri A, Vinel A, Valera MC, Guillaume M, Malet N, Foidart JM, Raymond-Letron I, Lenfant F, Gourdy P, Katzenellenbogen BS, Katzenellenbogen JA, Laffargue M, et al. The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells. Circulation Research. 117: 770-8. PMID 26316608 DOI: 10.1161/Circresaha.115.306416 |
0.343 |
|
| 2015 |
Durrant JD, Carlson KE, Martin TA, Offutt TL, Mayne CG, Katzenellenbogen JA, Amaro RE. Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. Journal of Chemical Information and Modeling. 55: 1953-61. PMID 26286148 DOI: 10.1021/Acs.Jcim.5B00241 |
0.708 |
|
| 2015 |
Valéra MC, Fontaine C, Lenfant F, Cabou C, Guillaume M, Smirnova N, Kim SH, Chambon P, Katzenellenbogen JA, Katzenellenbogen BS, Payrastre B, Arnal JF. Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α. Endocrinology. 156: 4293-301. PMID 26280130 DOI: 10.1210/En.2015-1522 |
0.352 |
|
| 2015 |
Kim SH, Madak-Erdogan Z, Bae SC, Carlson KE, Mayne CG, Granick S, Katzenellenbogen BS, Katzenellenbogen JA. Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History. Journal of the American Chemical Society. PMID 26186415 DOI: 10.1021/Jacs.5B05952 |
0.678 |
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| 2015 |
Bosch A, Li Z, Bergamaschi A, Ellis H, Toska E, Prat A, Tao JJ, Spratt DE, Viola-Villegas NT, Castel P, Minuesa G, Morse N, Rodón J, Ibrahim Y, Cortes J, ... ... Katzenellenbogen JA, et al. PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer. Science Translational Medicine. 7: 283ra51. PMID 25877889 DOI: 10.1126/Scitranslmed.Aaa4442 |
0.422 |
|
| 2015 |
Moore TW, Gunther JR, Katzenellenbogen JA. Estrogen receptor alpha/co-activator interaction assay: TR-FRET. Methods in Molecular Biology (Clifton, N.J.). 1278: 545-53. PMID 25859975 DOI: 10.1007/978-1-4939-2425-7_36 |
0.743 |
|
| 2015 |
Zhao Y, Gong P, Chen Y, Nwachukwu JC, Srinivasan S, Ko C, Bagchi MK, Taylor RN, Korach KS, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis. Science Translational Medicine. 7: 271ra9. PMID 25609169 DOI: 10.1126/Scitranslmed.3010626 |
0.35 |
|
| 2015 |
Paterni I, Bertini S, Granchi C, Tuccinardi T, Macchia M, Martinelli A, Caligiuri I, Toffoli G, Rizzolio F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Minutolo F. Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model. Journal of Medicinal Chemistry. 58: 1184-94. PMID 25559213 DOI: 10.1021/Jm501829F |
0.462 |
|
| 2015 |
Chan SR, Fowler AM, Allen JA, Zhou D, Dence CS, Sharp TL, Fettig NM, Dehdashti F, Katzenellenbogen JA. Longitudinal noninvasive imaging of progesterone receptor as a predictive biomarker of tumor responsiveness to estrogen deprivation therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1063-70. PMID 25520392 DOI: 10.1158/1078-0432.Ccr-14-1715 |
0.376 |
|
| 2015 |
Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07 |
0.76 |
|
| 2014 |
Gong P, Madak-Erdogan Z, Li J, Cheng J, Greenlief CM, Helferich W, Katzenellenbogen JA, Katzenellenbogen BS. Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens. Nuclear Receptor Signaling. 12: e001. PMID 25363786 DOI: 10.1621/Nrs.12001 |
0.353 |
|
| 2014 |
Abot A, Fontaine C, Buscato M, Solinhac R, Flouriot G, Fabre A, Drougard A, Rajan S, Laine M, Milon A, Muller I, Henrion D, Adlanmerini M, Valéra MC, Gompel A, ... ... Katzenellenbogen JA, et al. The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation. Embo Molecular Medicine. 6: 1328-46. PMID 25214462 DOI: 10.15252/Emmm.201404112 |
0.383 |
|
| 2014 |
Dabrota C, Asim M, Choueiri C, Gargaun A, Korobkov I, Butt A, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: comparison with the cis-fused isomers. Bioorganic & Medicinal Chemistry Letters. 24: 3841-4. PMID 25027938 DOI: 10.1016/J.Bmcl.2014.06.066 |
0.623 |
|
| 2014 |
Paterni I, Granchi C, Katzenellenbogen JA, Minutolo F. Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential. Steroids. 90: 13-29. PMID 24971815 DOI: 10.1016/J.Steroids.2014.06.012 |
0.452 |
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| 2014 |
Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Pérez Tenorio G, ... ... Katzenellenbogen JA, et al. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Research : Bcr. 16: R53. PMID 24886537 DOI: 10.1186/Bcr3664 |
0.352 |
|
| 2014 |
Zhou D, Lin M, Yasui N, Al-Qahtani MH, Dence CS, Schwarz S, Katzenellenbogen JA. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16alpha-[18F]fluoroestradiol (FES), [18F]fluoro furanyl norprogesterone (FFNP), and 16beta-[18F]fluoro-5alpha-dihydrotestosterone (FDHT) as radiopharmaceuticals. Journal of Labelled Compounds & Radiopharmaceuticals. 57: 371-7. PMID 24861984 DOI: 10.1002/Jlcr.3191 |
0.341 |
|
| 2014 |
Parent AA, Ess DH, Katzenellenbogen JA. π-π interaction energies as determinants of the photodimerization of mono-, di-, and triazastilbenes. The Journal of Organic Chemistry. 79: 5448-62. PMID 24837276 DOI: 10.1021/Jo500457N |
0.658 |
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| 2014 |
Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, et al. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife. 3: e02057. PMID 24771768 DOI: 10.7554/Elife.02057 |
0.79 |
|
| 2014 |
Royston SE, Yasui N, Kondilis AG, Lord SV, Katzenellenbogen JA, Mahoney MM. ESR1 and ESR2 differentially regulate daily and circadian activity rhythms in female mice. Endocrinology. 155: 2613-23. PMID 24735329 DOI: 10.1210/En.2014-1101 |
0.311 |
|
| 2014 |
Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor. Journal of Medicinal Chemistry. 57: 3532-45. PMID 24708493 DOI: 10.1021/Jm500268J |
0.613 |
|
| 2014 |
Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, et al. Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions. Proceedings of the National Academy of Sciences of the United States of America. 111: E283-90. PMID 24371309 DOI: 10.1073/Pnas.1322057111 |
0.407 |
|
| 2014 |
Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, et al. Author response: Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network Elife. DOI: 10.7554/Elife.02057.040 |
0.784 |
|
| 2014 |
Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot A, Boudou F, Sautier L, Vessieres E, Kim S, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, et al. 0053: The estrogen receptor alpha C451 palmitoylation site is absolutely required for vascular membrane-initiated action of estrogens in mice Archives of Cardiovascular Diseases Supplements. 6: 58-59. DOI: 10.1016/S1878-6480(14)71424-7 |
0.386 |
|
| 2014 |
Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Boudou F, Kim S, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen J, Gourdy P, Shaul P, Henrion D, et al. Mutation of palmitoylation site of Estrogen Receptor ER alpha in vivo reveals tissue-specific roles for membrane versus genomic effects of estrogens Annales D'Endocrinologie. 75: 270. DOI: 10.1016/J.Ando.2014.07.062 |
0.354 |
|
| 2013 |
Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y. Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 1: 5288-5297. PMID 24159374 DOI: 10.1039/C3Tb20412J |
0.329 |
|
| 2013 |
Wright JS, Anderson JM, Shadnia H, Durst T, Katzenellenbogen JA. Experimental versus predicted affinities for ligand binding to estrogen receptor: iterative selection and rescoring of docked poses systematically improves the correlation. Journal of Computer-Aided Molecular Design. 27: 707-21. PMID 23975271 DOI: 10.1007/S10822-013-9670-6 |
0.667 |
|
| 2013 |
Jiang Y, Gong P, Madak-Erdogan Z, Martin T, Jeyakumar M, Carlson K, Khan I, Smillie TJ, Chittiboyina AG, Rotte SC, Helferich WG, Katzenellenbogen JA, Katzenellenbogen BS. Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4406-18. PMID 23882126 DOI: 10.1096/Fj.13-234617 |
0.654 |
|
| 2013 |
Madak-Erdogan Z, Charn TH, Jiang Y, Liu ET, Katzenellenbogen JA, Katzenellenbogen BS. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 9: 676. PMID 23774759 DOI: 10.1038/Msb.2013.28 |
0.828 |
|
| 2013 |
Fan P, Griffith OL, Agboke FA, Anur P, Zou X, McDaniel RE, Creswell K, Kim SH, Katzenellenbogen JA, Gray JW, Jordan VC. c-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells. Cancer Research. 73: 4510-20. PMID 23704208 DOI: 10.1158/0008-5472.Can-12-4152 |
0.317 |
|
| 2013 |
Min J, Wang P, Srinivasan S, Nwachukwu JC, Guo P, Huang M, Carlson KE, Katzenellenbogen JA, Nettles KW, Zhou HB. Thiophene-core estrogen receptor ligands having superagonist activity. Journal of Medicinal Chemistry. 56: 3346-66. PMID 23586645 DOI: 10.1021/Jm400157E |
0.532 |
|
| 2013 |
Srinivasan S, Nwachukwu JC, Parent AA, Cavett V, Nowak J, Hughes TS, Kojetin DJ, Katzenellenbogen JA, Nettles KW. Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α. Nature Chemical Biology. 9: 326-32. PMID 23524984 DOI: 10.1038/Nchembio.1214 |
0.757 |
|
| 2013 |
Bartell SM, Han L, Kim HN, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Chambliss KL, Shaul PW, Roberson PK, Weinstein RS, Jilka RL, Almeida M, Manolagas SC. Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass. Molecular Endocrinology (Baltimore, Md.). 27: 649-56. PMID 23443267 DOI: 10.1210/Me.2012-1368 |
0.327 |
|
| 2013 |
Shan M, Carlson KE, Bujotzek A, Wellner A, Gust R, Weber M, Katzenellenbogen JA, Haag R. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. Acs Chemical Biology. 8: 707-15. PMID 23312071 DOI: 10.1021/Cb3006243 |
0.536 |
|
| 2013 |
Lee BC, Moon BS, Kim JS, Jung JH, Park HS, Katzenellenbogen JA, Kim SE. Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: Highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis Rsc Advances. 3: 782-792. DOI: 10.1039/C2Ra22460G |
0.317 |
|
| 2012 |
Zhu M, Zhang C, Nwachukwu JC, Srinivasan S, Cavett V, Zheng Y, Carlson KE, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides. Organic & Biomolecular Chemistry. 10: 8692-700. PMID 23033157 DOI: 10.1039/C2Ob26531A |
0.55 |
|
| 2012 |
Sepehr E, Lebl-Rinnova M, Mann MK, Pisani SL, Churchwell MI, Korol DL, Katzenellenbogen JA, Doerge DR. Pharmacokinetics of the estrogen receptor subtype-selective ligands, PPT and DPN: quantification using UPLC-ES/MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 71: 119-26. PMID 22981216 DOI: 10.1016/J.Jpba.2012.08.022 |
0.742 |
|
| 2012 |
Kim Y, Kim SH, Ferracane D, Katzenellenbogen JA, Schroeder CM. Specific labeling of zinc finger proteins using noncanonical amino acids and copper-free click chemistry. Bioconjugate Chemistry. 23: 1891-901. PMID 22871171 DOI: 10.1021/Bc300262H |
0.312 |
|
| 2012 |
Lee JH, Peters O, Lehmann L, Dence CS, Sharp TL, Carlson KE, Zhou D, Jeyakumar M, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of two agents for imaging estrogen receptor β by positron emission tomography: challenges in PET imaging of a low abundance target. Nuclear Medicine and Biology. 39: 1105-16. PMID 22749433 DOI: 10.1016/J.Nucmedbio.2012.05.011 |
0.445 |
|
| 2012 |
Fowler AM, Chan SR, Sharp TL, Fettig NM, Zhou D, Dence CS, Carlson KE, Jeyakumar M, Katzenellenbogen JA, Schreiber RD, Welch MJ. Small-animal PET of steroid hormone receptors predicts tumor response to endocrine therapy using a preclinical model of breast cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1119-26. PMID 22669982 DOI: 10.2967/Jnumed.112.103465 |
0.346 |
|
| 2012 |
Asim M, Klonowska D, Choueiri C, Korobkov I, Carlson KE, Katzenellenbogen JA, Durst T. BC-spiro-estradiols. Synthesis and estrogen receptor binding affinity of four new estradiol isomers. Bioorganic & Medicinal Chemistry Letters. 22: 3713-7. PMID 22546676 DOI: 10.1016/J.Bmcl.2012.04.022 |
0.704 |
|
| 2012 |
Zheng Y, Zhu M, Srinivasan S, Nwachukwu JC, Cavett V, Min J, Carlson KE, Wang P, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands. Chemmedchem. 7: 1094-100. PMID 22517684 DOI: 10.1002/Cmdc.201200048 |
0.563 |
|
| 2012 |
Dehdashti F, Laforest R, Gao F, Aft RL, Dence CS, Zhou D, Shoghi KI, Siegel BA, Katzenellenbogen JA, Welch MJ. Assessment of progesterone receptors in breast carcinoma by PET with 21-18F-fluoro-16α,17α-[(R)-(1'-α-furylmethylidene)dioxy]-19-norpregn-4-ene-3,20-dione. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 363-70. PMID 22331216 DOI: 10.2967/Jnumed.111.098319 |
0.332 |
|
| 2012 |
Wang P, Min J, Nwachukwu JC, Cavett V, Carlson KE, Guo P, Zhu M, Zheng Y, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide. Journal of Medicinal Chemistry. 55: 2324-41. PMID 22283328 DOI: 10.1021/Jm201556R |
0.519 |
|
| 2012 |
Carroll VM, Jeyakumar M, Carlson KE, Katzenellenbogen JA. Diarylpropionitrile (DPN) enantiomers: synthesis and evaluation of estrogen receptor β-selective ligands. Journal of Medicinal Chemistry. 55: 528-37. PMID 22122563 DOI: 10.1021/Jm201436K |
0.519 |
|
| 2012 |
Mayne CG, Katzenellenbogen JA, Tajkhorshid E. Characterizing Structural and Dynamical Impacts of Agonist- and Antsgonist-Stabilized Mutants of the Estrogen Receptor Biophysical Journal. 102: 457a. DOI: 10.1016/J.Bpj.2011.11.2508 |
0.707 |
|
| 2011 |
Miller CP, Shomali M, Lyttle CR, O'Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS, Nickels M, Green JL, Katzenellenbogen JA, Tchesnokov A, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. Acs Medicinal Chemistry Letters. 2: 124-9. PMID 24900290 DOI: 10.1021/Ml1002508 |
0.818 |
|
| 2011 |
Paulmurugan R, Tamrazi A, Massoud TF, Katzenellenbogen JA, Gambhir SS. In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. Molecular Endocrinology (Baltimore, Md.). 25: 2029-40. PMID 22052998 DOI: 10.1210/Me.2011-1145 |
0.797 |
|
| 2011 |
McLachlan MJ, Katzenellenbogen JA, Zhao H. A new fluorescence complementation biosensor for detection of estrogenic compounds. Biotechnology and Bioengineering. 108: 2794-803. PMID 21732327 DOI: 10.1002/Bit.23254 |
0.409 |
|
| 2011 |
Katzenellenbogen JA. The 2010 Philip S. Portoghese Medicinal Chemistry Lectureship: addressing the "core issue" in the design of estrogen receptor ligands. Journal of Medicinal Chemistry. 54: 5271-82. PMID 21707083 DOI: 10.1021/Jm200801H |
0.456 |
|
| 2011 |
Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell. 145: 584-95. PMID 21565615 DOI: 10.1016/J.Cell.2011.03.050 |
0.398 |
|
| 2011 |
Bertini S, De Cupertinis A, Granchi C, Bargagli B, Tuccinardi T, Martinelli A, Macchia M, Gunther JR, Carlson KE, Katzenellenbogen JA, Minutolo F. Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes. European Journal of Medicinal Chemistry. 46: 2453-62. PMID 21481497 DOI: 10.1016/J.Ejmech.2011.03.030 |
0.674 |
|
| 2011 |
Sun A, Moore TW, Gunther JR, Kim MS, Rhoden E, Du Y, Fu H, Snyder JP, Katzenellenbogen JA. Discovering small-molecule estrogen receptor α/coactivator binding inhibitors: high-throughput screening, ligand development, and models for enhanced potency. Chemmedchem. 6: 654-66. PMID 21365764 DOI: 10.1002/Cmdc.201000507 |
0.805 |
|
| 2011 |
Jeyakumar M, Carlson KE, Gunther JR, Katzenellenbogen JA. Exploration of dimensions of estrogen potency: parsing ligand binding and coactivator binding affinities. The Journal of Biological Chemistry. 286: 12971-82. PMID 21321128 DOI: 10.1074/Jbc.M110.205112 |
0.712 |
|
| 2011 |
Cheong SJ, Jang D, Jeong HJ, Lim ST, Sohn MH, Katzenellenbogen JA, Kim DW. Reduction of stimulated sodium iodide symporter expression by estrogen receptor ligands in breast cancer cells. Nuclear Medicine and Biology. 38: 287-94. PMID 21315285 DOI: 10.1016/J.Nucmedbio.2010.07.010 |
0.385 |
|
| 2011 |
Wright JS, Shadnia H, Anderson JM, Durst T, Asim M, El-Salfiti M, Choueiri C, Pratt MA, Ruddy SC, Lau R, Carlson KE, Katzenellenbogen JA, O'Brien PJ, Wan L. A-CD estrogens. I. Substituent effects, hormone potency, and receptor subtype selectivity in a new family of flexible estrogenic compounds. Journal of Medicinal Chemistry. 54: 433-48. PMID 21190382 DOI: 10.1021/Jm100513M |
0.691 |
|
| 2011 |
Minutolo F, Macchia M, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor β ligands: recent advances and biomedical applications. Medicinal Research Reviews. 31: 364-442. PMID 19967775 DOI: 10.1002/Med.20186 |
0.406 |
|
| 2010 |
Bruning JB, Parent AA, Gil G, Zhao M, Nowak J, Pace MC, Smith CL, Afonine PV, Adams PD, Katzenellenbogen JA, Nettles KW. Coupling of receptor conformation and ligand orientation determine graded activity. Nature Chemical Biology. 6: 837-43. PMID 20924370 DOI: 10.1038/Nchembio.451 |
0.764 |
|
| 2010 |
Moore TW, Gunther JR, Katzenellenbogen JA. Probing the topological tolerance of multimeric protein interactions: evaluation of an estrogen/synthetic ligand for FK506 binding protein conjugate. Bioconjugate Chemistry. 21: 1880-9. PMID 20919698 DOI: 10.1021/Bc100266V |
0.786 |
|
| 2010 |
Ackroyd NC, Katzenellenbogen JA. Pyridyl-Cyclopentadiene Re(CO)(2) Complexes as a Compact Core Systems for SPECT Ligand Development. Organometallics. 29: 3669-3671. PMID 20865134 DOI: 10.1021/Om100521S |
0.783 |
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| 2010 |
Neese SL, Korol DL, Katzenellenbogen JA, Schantz SL. Impact of estrogen receptor alpha and beta agonists on delayed alternation in middle-aged rats. Hormones and Behavior. 58: 878-90. PMID 20816967 DOI: 10.1016/J.Yhbeh.2010.08.017 |
0.334 |
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| 2010 |
Santollo J, Katzenellenbogen BS, Katzenellenbogen JA, Eckel LA. Activation of ERα is necessary for estradiol's anorexigenic effect in female rats. Hormones and Behavior. 58: 872-7. PMID 20807534 DOI: 10.1016/J.Yhbeh.2010.08.012 |
0.364 |
|
| 2010 |
Wong WP, Tiano JP, Liu S, Hewitt SC, Le May C, Dalle S, Katzenellenbogen JA, Katzenellenbogen BS, Korach KS, Mauvais-Jarvis F. Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 13057-62. PMID 20616010 DOI: 10.1073/Pnas.0914501107 |
0.324 |
|
| 2010 |
Chambliss KL, Wu Q, Oltmann S, Konaniah ES, Umetani M, Korach KS, Thomas GD, Mineo C, Yuhanna IS, Kim SH, Madak-Erdogan Z, Maggi A, Dineen SP, Roland CL, Hui DY, ... ... Katzenellenbogen JA, et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. The Journal of Clinical Investigation. 120: 2319-30. PMID 20577047 DOI: 10.1172/Jci38291 |
0.431 |
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| 2010 |
Lee JH, Zhou HB, Dence CS, Carlson KE, Welch MJ, Katzenellenbogen JA. Development of [F-18]fluorine-substituted Tanaproget as a progesterone receptor imaging agent for positron emission tomography. Bioconjugate Chemistry. 21: 1096-104. PMID 20496889 DOI: 10.1021/Bc1001054 |
0.413 |
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| 2010 |
Zhou HB, Lee JH, Mayne CG, Carlson KE, Katzenellenbogen JA. Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget. Journal of Medicinal Chemistry. 53: 3349-60. PMID 20355713 DOI: 10.1021/Jm100052K |
0.762 |
|
| 2010 |
Kieser KJ, Kim DW, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs). Journal of Medicinal Chemistry. 53: 3320-9. PMID 20334372 DOI: 10.1021/Jm100047K |
0.52 |
|
| 2010 |
Kim SH, Gunther JR, Katzenellenbogen JA. Monitoring a coordinated exchange process in a four-component biological interaction system: development of a time-resolved terbium-based one-donor/three-acceptor multicolor FRET system. Journal of the American Chemical Society. 132: 4685-92. PMID 20230029 DOI: 10.1021/Ja100248Q |
0.651 |
|
| 2010 |
Moore TW, Mayne CG, Katzenellenbogen JA. Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs). Molecular Endocrinology (Baltimore, Md.). 24: 683-95. PMID 19933380 DOI: 10.1210/Me.2009-0362 |
0.821 |
|
| 2010 |
Charn TH, Liu ET, Chang EC, Lee YK, Katzenellenbogen JA, Katzenellenbogen BS. Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Molecular Endocrinology (Baltimore, Md.). 24: 47-59. PMID 19897598 DOI: 10.1210/Me.2009-0252 |
0.843 |
|
| 2010 |
Gao H, Katzenellenbogen JA, Garg R, Hansch C. ChemInform Abstract: Comparative QSAR Analysis of Estrogen Receptor Ligands Cheminform. 30: no-no. DOI: 10.1002/CHIN.199921279 |
0.406 |
|
| 2010 |
Spradau TW, Katzenellenbogen JA. ChemInform Abstract: Ligands for the Estrogen Receptor, Containing Cyclopentadienyltricarbonylrhenium Units. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199912201 |
0.397 |
|
| 2010 |
MAZUR BOWEN C, KATZENELLENBOGEN JA. ChemInform Abstract: Synthesis and Spectroscopic Characterization of Two Azatetrahydrochrysenes as Potential Fluorescent Ligands for the Estrogen Receptor. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199813127 |
0.388 |
|
| 2010 |
TEDESCO R, KATZENELLENBOGEN JA, NAPOLITANO E. ChemInform Abstract: 7α,11β-Disubstituted Estrogens: Probes for the Shape of the Ligand Binding Pocket in the Estrogen Receptor. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199810215 |
0.358 |
|
| 2010 |
KYM PR, CARLSON KE, KATZENELLENBOGEN JA. ChemInform Abstract: Evaluation of a Highly Efficient Aryl Azide Photoaffinity Labeling Reagent for the Progesterone Receptor. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199528210 |
0.301 |
|
| 2010 |
VANBROCKLIN HF, CARLSON KE, KATZENELLENBOGEN JA, WELCH MJ. ChemInform Abstract: 16β-((18F)Fluoro)estrogens: Systematic Investigation of a New Series of Fluorine-18-Labeled Estrogens as Potential Imaging Agents for Estrogen-Receptor-Positive Breast Tumors. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199335310 |
0.309 |
|
| 2010 |
HWANG K, O'NEIL JP, KATZENELLENBOGEN JA. ChemInform Abstract: 5,6,11,12-Tetrahydrochrysenes: Synthesis of Rigid Stilbene Systems Designed to be Fluorescent Ligands for the Estrogen Receptor. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199230132 |
0.342 |
|
| 2009 |
Williams AB, Weiser PT, Hanson RN, Gunther JR, Katzenellenbogen JA. Synthesis of biphenyl proteomimetics as estrogen receptor-alpha coactivator binding inhibitors. Organic Letters. 11: 5370-3. PMID 19902964 DOI: 10.1021/Ol901999F |
0.667 |
|
| 2009 |
Gunther JR, Parent AA, Katzenellenbogen JA. Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors. Acs Chemical Biology. 4: 435-40. PMID 19441848 DOI: 10.1021/Cb900043E |
0.813 |
|
| 2009 |
LaFrate AL, Carlson KE, Katzenellenbogen JA. Steroidal bivalent ligands for the estrogen receptor: design, synthesis, characterization and binding affinities. Bioorganic & Medicinal Chemistry. 17: 3528-35. PMID 19394231 DOI: 10.1016/J.Bmc.2009.04.016 |
0.849 |
|
| 2009 |
Waibel M, Kieser KJ, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta. European Journal of Medicinal Chemistry. 44: 3560-70. PMID 19394116 DOI: 10.1016/J.Ejmech.2009.03.013 |
0.505 |
|
| 2009 |
Moon BS, Carlson KE, Katzenellenbogen JA, Choi TH, Chi DY, Kim JY, Cheon GJ, Koh HY, Lee KC, An G. Synthesis and evaluation of aryl-substituted diarylpropionitriles, selective ligands for estrogen receptor beta, as positron-emission tomographic imaging agents. Bioorganic & Medicinal Chemistry. 17: 3479-88. PMID 19359182 DOI: 10.1016/J.Bmc.2009.02.064 |
0.682 |
|
| 2009 |
Waibel M, De Angelis M, Stossi F, Kieser KJ, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta. European Journal of Medicinal Chemistry. 44: 3412-24. PMID 19286283 DOI: 10.1016/J.Ejmech.2009.02.006 |
0.487 |
|
| 2009 |
Zhou D, Zhou H, Jenks CC, Lewis JS, Katzenellenbogen JA, Welch MJ. Bromination from the macroscopic level to the tracer radiochemical level: (76)Br radiolabeling of aromatic compounds via electrophilic substitution. Bioconjugate Chemistry. 20: 808-16. PMID 19260733 DOI: 10.1021/Bc800313C |
0.348 |
|
| 2009 |
Lee BC, Dence CS, Zhou H, Parent EE, Welch MJ, Katzenellenbogen JA. Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-gamma ligands: potential positron emission tomography imaging agents. Nuclear Medicine and Biology. 36: 147-53. PMID 19217526 DOI: 10.1016/J.Nucmedbio.2008.11.002 |
0.679 |
|
| 2009 |
Gunther JR, Du Y, Rhoden E, Lewis I, Revennaugh B, Moore TW, Kim SH, Dingledine R, Fu H, Katzenellenbogen JA. A set of time-resolved fluorescence resonance energy transfer assays for the discovery of inhibitors of estrogen receptor-coactivator binding. Journal of Biomolecular Screening. 14: 181-93. PMID 19196699 DOI: 10.1177/1087057108329349 |
0.8 |
|
| 2009 |
Asim M, Asim M, El-Salfiti M, Qian Y, Choueiri C, Salari S, Cheng J, Shadnia H, Bal M, Christine Pratt MA, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Deconstructing estradiol: removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists. Bioorganic & Medicinal Chemistry Letters. 19: 1250-3. PMID 19167882 DOI: 10.1016/J.Bmcl.2008.12.080 |
0.659 |
|
| 2009 |
Minutolo F, Bertini S, Granchi C, Marchitiello T, Prota G, Rapposelli S, Tuccinardi T, Martinelli A, Gunther JR, Carlson KE, Katzenellenbogen JA, Macchia M. Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor beta. Journal of Medicinal Chemistry. 52: 858-67. PMID 19128016 DOI: 10.1021/Jm801458T |
0.69 |
|
| 2009 |
Jeyakumar M, Katzenellenbogen JA. A dual-acceptor time-resolved Föster resonance energy transfer assay for simultaneous determination of thyroid hormone regulation of corepressor and coactivator binding to the thyroid hormone receptor: Mimicking the cellular context of thyroid hormone action. Analytical Biochemistry. 386: 73-8. PMID 19111515 DOI: 10.1016/J.Ab.2008.11.039 |
0.457 |
|
| 2009 |
Trogden BG, Kim SH, Lee S, Katzenellenbogen JA. Tethered indoles as functionalizable ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 19: 485-8. PMID 19059778 DOI: 10.1016/J.Bmcl.2008.11.043 |
0.85 |
|
| 2009 |
Zhou HB, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity. Bioorganic & Medicinal Chemistry Letters. 19: 108-10. PMID 19014882 DOI: 10.1016/J.Bmcl.2008.11.006 |
0.451 |
|
| 2009 |
Dehdashti F, Mortimer JE, Trinkaus K, Naughton MJ, Ellis M, Katzenellenbogen JA, Welch MJ, Siegel BA. PET-based estradiol challenge as a predictive biomarker of response to endocrine therapy in women with estrogen-receptor-positive breast cancer. Breast Cancer Research and Treatment. 113: 509-17. PMID 18327670 DOI: 10.1007/S10549-008-9953-0 |
0.334 |
|
| 2009 |
Moore TW, Katzenellenbogen JA. Inhibitors of nuclear hormone receptor/coactivator interactions Annual Reports in Medicinal Chemistry. 44: 443-457. DOI: 10.1016/S0065-7743(09)04421-2 |
0.731 |
|
| 2009 |
Asim M, El-Salfiti M, Qian Y, Choueiri C, Salari S, Cheng J, Shadnia H, Bal M, Christine Pratt MA, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Corrigendum to "Deconstructing estradiol: Removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists" [Bioorg. Med. Chem. Lett. 19 (2009) 1250-1253] (DOI:10.1016/j.bmcl.2008.12.080) Bioorganic and Medicinal Chemistry Letters. 19: 2605. DOI: 10.1016/J.Bmcl.2008.12.117 |
0.649 |
|
| 2008 |
LaFrate AL, Gunther JR, Carlson KE, Katzenellenbogen JA. Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorganic & Medicinal Chemistry. 16: 10075-84. PMID 18976929 DOI: 10.1016/J.Bmc.2008.10.007 |
0.849 |
|
| 2008 |
Kim SH, Gunther JR, Katzenellenbogen JA. Nonclassical SNAPFL analogue as a Cy5 resonance energy transfer partner. Organic Letters. 10: 4931-4. PMID 18841988 DOI: 10.1021/Ol801907B |
0.63 |
|
| 2008 |
Parent AA, Gunther JR, Katzenellenbogen JA. Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding. Journal of Medicinal Chemistry. 51: 6512-30. PMID 18785725 DOI: 10.1021/Jm800698B |
0.825 |
|
| 2008 |
Zhou D, Sharp TL, Fettig NM, Lee H, Lewis JS, Katzenellenbogen JA, Welch MJ. Evaluation of a bromine-76-labeled progestin 16alpha,17alpha-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies. Nuclear Medicine and Biology. 35: 655-63. PMID 18678350 DOI: 10.1016/J.Nucmedbio.2008.05.001 |
0.307 |
|
| 2008 |
Jeyakumar M, Webb P, Baxter JD, Scanlan TS, Katzenellenbogen JA. Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor. Biochemistry. 47: 7465-76. PMID 18558711 DOI: 10.1021/Bi800393U |
0.495 |
|
| 2008 |
Alyea RA, Laurence SE, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Watson CS. The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells. Journal of Neurochemistry. 106: 1525-33. PMID 18489713 DOI: 10.1111/J.1471-4159.2008.05491.X |
0.344 |
|
| 2008 |
Gunther JR, Moore TW, Collins ML, Katzenellenbogen JA. Amphipathic benzenes are designed inhibitors of the estrogen receptor alpha/steroid receptor coactivator interaction. Acs Chemical Biology. 3: 282-6. PMID 18484708 DOI: 10.1021/Cb800056R |
0.832 |
|
| 2008 |
Parent EE, Dence CS, Sharp TL, Welch MJ, Katzenellenbogen JA. 7alpha-18F-fluoromethyl-dihydrotestosterone and 7alpha-18F-fluoromethyl-nortestosterone: ligands to determine the role of sex hormone-binding globulin for steroidal radiopharmaceuticals. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 987-94. PMID 18483103 DOI: 10.2967/Jnumed.107.048926 |
0.66 |
|
| 2008 |
Paulmurugan R, Tamrazi A, Katzenellenbogen JA, Katzenellenbogen BS, Gambhir SS. A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Molecular Endocrinology (Baltimore, Md.). 22: 1552-64. PMID 18451095 DOI: 10.1210/Me.2007-0570 |
0.803 |
|
| 2008 |
Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses. Nature Chemical Biology. 4: 241-7. PMID 18344977 DOI: 10.1038/Nchembio.76 |
0.485 |
|
| 2008 |
Minutolo F, Bellini R, Bertini S, Carboni I, Lapucci A, Pistolesi L, Prota G, Rapposelli S, Solati F, Tuccinardi T, Martinelli A, Stossi F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, et al. Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta. Journal of Medicinal Chemistry. 51: 1344-51. PMID 18269232 DOI: 10.1021/Jm701396G |
0.505 |
|
| 2008 |
Chang EC, Charn TH, Park SH, Helferich WG, Komm B, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Molecular Endocrinology (Baltimore, Md.). 22: 1032-43. PMID 18258689 DOI: 10.1210/Me.2007-0356 |
0.832 |
|
| 2008 |
Kim DW, Jeong HJ, Lim ST, Sohn MH, Katzenellenbogen JA, Chi DY. Facile nucleophilic fluorination reactions using tert-alcohols as a reaction medium: significantly enhanced reactivity of alkali metal fluorides and improved selectivity. The Journal of Organic Chemistry. 73: 957-62. PMID 18166063 DOI: 10.1021/Jo7021229 |
0.51 |
|
| 2008 |
Seo JW, Kim HJ, Lee BS, Katzenellenbogen JA, Chi DY. Convenient one-pot synthesis of 2,2-bis-(4-hydroxyphenyl)-cyclopentanone. The Journal of Organic Chemistry. 73: 715-8. PMID 18088140 DOI: 10.1021/Jo701850U |
0.548 |
|
| 2008 |
Wuest F, Carlson KE, Katzenellenbogen JA. Expeditious synthesis of steroids containing a 2-methylsulfanyl-acetyl side chain as potential glucocorticoid receptor imaging agents. Steroids. 73: 69-76. PMID 17942130 DOI: 10.1016/J.Steroids.2007.08.013 |
0.444 |
|
| 2008 |
Byung SM, Katzenellenbogen JA, Gi JC, Dae YC, Kyo CL, Gwang IA. Synthesis and evaluation of estrogen receptor β-selective ligands: Fluoroalkylated indazole estrogens Bulletin of the Korean Chemical Society. 29: 1107-1114. DOI: 10.5012/Bkcs.2008.29.6.1107 |
0.543 |
|
| 2008 |
Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachimiak A, Greene GL. Corrigendum: NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses (Nature Chemical Biology (2008) 4, (241-247)) Nature Chemical Biology. 4: 379. DOI: 10.1038/Nchembio0608-379B |
0.501 |
|
| 2007 |
Kim SH, Jeyakumar M, Katzenellenbogen JA. Dual-mode fluorophore-doped nickel nitrilotriacetic acid-modified silica nanoparticles combine histidine-tagged protein purification with site-specific fluorophore labeling. Journal of the American Chemical Society. 129: 13254-64. PMID 17910454 DOI: 10.1021/Ja074443F |
0.366 |
|
| 2007 |
LaFrate AL, Katzenellenbogen JA. Improved chemical syntheses of 5,6-dihydro-5-fluorouracil. The Journal of Organic Chemistry. 72: 8573-6. PMID 17900141 DOI: 10.1021/Jo071255Z |
0.774 |
|
| 2007 |
Parent EE, Carlson KE, Katzenellenbogen JA. Synthesis of 7alpha-(fluoromethyl)dihydrotestosterone and 7alpha-(fluoromethyl)nortestosterone, structurally paired androgens designed to probe the role of sex hormone binding globulin in imaging androgen receptors in prostate tumors by positron emission tomography. The Journal of Organic Chemistry. 72: 5546-54. PMID 17585812 DOI: 10.1021/Jo070328B |
0.693 |
|
| 2007 |
Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA. Elemental Isomerism: A Boron-Nitrogen Surrogate for a Carbon-Carbon Double Bond Increases the Chemical Diversity of Estrogen Receptor Ligands Chemistry and Biology. 14: 659-669. PMID 17584613 DOI: 10.1016/J.Chembiol.2007.04.009 |
0.442 |
|
| 2007 |
Zhou HB, Collins ML, Gunther JR, Comninos JS, Katzenellenbogen JA. Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators. Bioorganic & Medicinal Chemistry Letters. 17: 4118-22. PMID 17560105 DOI: 10.1016/J.Bmcl.2007.05.058 |
0.829 |
|
| 2007 |
Seo JW, Chi DY, Dence CS, Welch MJ, Katzenellenbogen JA. Synthesis and biodistribution of fluorine-18-labeled fluorocyclofenils for imaging the estrogen receptor. Nuclear Medicine and Biology. 34: 383-90. PMID 17499727 DOI: 10.1016/J.Nucmedbio.2007.01.010 |
0.663 |
|
| 2007 |
Parent EE, Dence CS, Jenks C, Sharp TL, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging. Journal of Medicinal Chemistry. 50: 1028-40. PMID 17328524 DOI: 10.1021/Jm060847R |
0.688 |
|
| 2007 |
Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Strategies for the labeling of halogen-substituted peroxisome proliferator-activated receptor gamma ligands: potential positron emission tomography and single photon emission computed tomography imaging agents. Bioconjugate Chemistry. 18: 514-23. PMID 17315977 DOI: 10.1021/Bc060191G |
0.459 |
|
| 2007 |
Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Synthesis and binding affinity of a fluorine-substituted peroxisome proliferator-activated gamma (PPARgamma) ligand as a potential positron emission tomography (PET) imaging agent. Bioconjugate Chemistry. 18: 507-13. PMID 17309226 DOI: 10.1021/Bc060190O |
0.41 |
|
| 2007 |
Lupien M, Jeyakumar M, Hébert E, Hilmi K, Cotnoir-White D, Loch C, Auger A, Dayan G, Pinard GA, Wurtz JM, Moras D, Katzenellenbogen J, Mader S. Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. Molecular Endocrinology (Baltimore, Md.). 21: 797-816. PMID 17299137 DOI: 10.1210/Me.2006-0074 |
0.489 |
|
| 2007 |
Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, Sharma S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA. Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. Journal of Medicinal Chemistry. 50: 399-403. PMID 17228884 DOI: 10.1021/Jm061035Y |
0.758 |
|
| 2006 |
Dahlman-Wright K, Cavailles V, Fuqua SA, Jordan VC, Katzenellenbogen JA, Korach KS, Maggi A, Muramatsu M, Parker MG, Gustafsson JA. International Union of Pharmacology. LXIV. Estrogen receptors. Pharmacological Reviews. 58: 773-81. PMID 17132854 DOI: 10.1124/Pr.58.4.8 |
0.515 |
|
| 2006 |
Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates. Journal of the American Chemical Society. 128: 14476-7. PMID 17090028 DOI: 10.1021/Ja066360P |
0.504 |
|
| 2006 |
Kim SH, Katzenellenbogen JA. Hormone-PAMAM dendrimer conjugates: polymer dynamics and tether structure affect ligand access to receptors. Angewandte Chemie (International Ed. in English). 45: 7243-8. PMID 17024710 DOI: 10.1002/Anie.200601923 |
0.404 |
|
| 2006 |
Likhite VS, Stossi F, Kim K, Katzenellenbogen BS, Katzenellenbogen JA. Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity. Molecular Endocrinology (Baltimore, Md.). 20: 3120-32. PMID 16945990 DOI: 10.1210/Me.2006-0068 |
0.367 |
|
| 2006 |
Parent EE, Jenks C, Sharp T, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide. Nuclear Medicine and Biology. 33: 705-13. PMID 16934689 DOI: 10.1016/J.Nucmedbio.2006.05.009 |
0.717 |
|
| 2006 |
Jacobson O, Laky D, Carlson KE, Elgavish S, Gozin M, Even-Sapir E, Leibovitc I, Gutman M, Chisin R, Katzenellenbogen JA, Mishani E. Chiral dimethylamine flutamide derivatives--modeling, synthesis, androgen receptor affinities and carbon-11 labeling. Nuclear Medicine and Biology. 33: 695-704. PMID 16934688 DOI: 10.1016/J.Nucmedbio.2006.05.010 |
0.347 |
|
| 2006 |
Tuccinardi T, Bertini S, Martinelli A, Minutolo F, Ortore G, Placanica G, Prota G, Rapposelli S, Carlson KE, Katzenellenbogen JA, Macchia M. Synthesis of anthranylaldoxime derivatives as estrogen receptor ligands and computational prediction of binding modes. Journal of Medicinal Chemistry. 49: 5001-12. PMID 16884312 DOI: 10.1021/Jm060560U |
0.486 |
|
| 2006 |
Zhou D, Carlson KE, Katzenellenbogen JA, Welch MJ. Bromine- and iodine-substituted 16alpha,17alpha-dioxolane progestins for breast tumor imaging and radiotherapy: synthesis and receptor binding affinity. Journal of Medicinal Chemistry. 49: 4737-44. PMID 16854080 DOI: 10.1021/Jm060348Q |
0.355 |
|
| 2006 |
Parent EE, Dence CS, Sharp TL, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a fluorine-18-labeled nonsteroidal androgen receptor antagonist, N-(3-[18F]fluoro-4-nitronaphthyl)-cis-5-norbornene-endo-2,3-dicarboxylic imide. Nuclear Medicine and Biology. 33: 615-24. PMID 16843836 DOI: 10.1016/J.Nucmedbio.2006.04.003 |
0.705 |
|
| 2006 |
Dayan G, Lupien M, Auger A, Anghel SI, Rocha W, Croisetière S, Katzenellenbogen JA, Mader S. Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor alpha. Molecular Pharmacology. 70: 579-88. PMID 16679488 DOI: 10.1124/Mol.105.021931 |
0.421 |
|
| 2006 |
Seo JW, Comninos JS, Chi DY, Kim DW, Carlson KE, Katzenellenbogen JA. Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer. Journal of Medicinal Chemistry. 49: 2496-511. PMID 16610793 DOI: 10.1021/Jm0512037 |
0.831 |
|
| 2006 |
Stossi F, Likhite VS, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter. The Journal of Biological Chemistry. 281: 16272-8. PMID 16608856 DOI: 10.1074/Jbc.M513405200 |
0.42 |
|
| 2006 |
Harrington WR, Kim SH, Funk CC, Madak-Erdogan Z, Schiff R, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Molecular Endocrinology (Baltimore, Md.). 20: 491-502. PMID 16306086 DOI: 10.1210/Me.2005-0186 |
0.332 |
|
| 2006 |
Mishra RG, Stanczyk FZ, Burry KA, Oparil S, Katzenellenbogen BS, Nealen ML, Katzenellenbogen JA, Hermsmeyer RK. Metabolite ligands of estrogen receptor-beta reduce primate coronary hyperreactivity. American Journal of Physiology. Heart and Circulatory Physiology. 290: H295-303. PMID 16199482 DOI: 10.1152/Ajpheart.00468.2005 |
0.323 |
|
| 2006 |
Minutolo F, Bertini S, Martinelli A, Ortore G, Placanica G, Prota G, Rapposelli S, Tuccinardi T, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M. Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands Arkivoc. 2006: 83-94. DOI: 10.3998/Ark.5550190.0007.809 |
0.509 |
|
| 2005 |
Zhou HB, Comninos JS, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure. Journal of Medicinal Chemistry. 48: 7261-74. PMID 16279785 DOI: 10.1021/Jm0506773 |
0.85 |
|
| 2005 |
Yoo J, Dence CS, Sharp TL, Katzenellenbogen JA, Welch MJ. Synthesis of an estrogen receptor beta-selective radioligand: 5-[18F]fluoro-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile and comparison of in vivo distribution with 16alpha-[18F]fluoro-17beta-estradiol. Journal of Medicinal Chemistry. 48: 6366-78. PMID 16190762 DOI: 10.1021/Jm050121F |
0.405 |
|
| 2005 |
De Angelis M, Stossi F, Waibel M, Katzenellenbogen BS, Katzenellenbogen JA. Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites. Bioorganic & Medicinal Chemistry. 13: 6529-42. PMID 16099659 DOI: 10.1016/J.Bmc.2005.07.014 |
0.482 |
|
| 2005 |
Katzenellenbogen JA. Designing effective hybrid toxins. Chemistry & Biology. 12: 719-21. PMID 16039518 DOI: 10.1016/J.Chembiol.2005.07.002 |
0.353 |
|
| 2005 |
Chockalingam K, Chen Z, Katzenellenbogen JA, Zhao H. Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. Proceedings of the National Academy of Sciences of the United States of America. 102: 5691-6. PMID 15811944 DOI: 10.1073/Pnas.0409206102 |
0.488 |
|
| 2005 |
Bigott HM, Parent E, Luyt LG, Katzenellenbogen JA, Welch MJ. Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry. 16: 255-64. PMID 15769078 DOI: 10.1021/Bc049770G |
0.813 |
|
| 2005 |
De Angelis M, Stossi F, Carlson KA, Katzenellenbogen BS, Katzenellenbogen JA. Indazole estrogens: highly selective ligands for the estrogen receptor beta. Journal of Medicinal Chemistry. 48: 1132-44. PMID 15715479 DOI: 10.1021/Jm049223G |
0.494 |
|
| 2005 |
Tamrazi A, Carlson KE, Rodriguez AL, Katzenellenbogen JA. Coactivator proteins as determinants of estrogen receptor structure and function: spectroscopic evidence for a novel coactivator-stabilized receptor conformation. Molecular Endocrinology (Baltimore, Md.). 19: 1516-28. PMID 15661830 DOI: 10.1210/Me.2004-0458 |
0.849 |
|
| 2005 |
Kim SH, Tamrazi A, Carlson KE, Katzenellenbogen JA. A proteomic microarray approach for exploring ligand-initiated nuclear hormone receptor pharmacology, receptor selectivity, and heterodimer functionality. Molecular & Cellular Proteomics : McP. 4: 267-77. PMID 15613364 DOI: 10.1074/Mcp.M400192-Mcp200 |
0.8 |
|
| 2005 |
Chu CK, Kim JH, Kim DW, Chung KH, Katzenellenbogen JA, Chi DY. Aromatic fluorination by decomposition of triazenes in ionic liquids Bulletin of the Korean Chemical Society. 26: 599-602. DOI: 10.5012/Bkcs.2005.26.4.599 |
0.519 |
|
| 2004 |
Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. Journal of Medicinal Chemistry. 47: 5872-93. PMID 15537344 DOI: 10.1021/Jm049631K |
0.774 |
|
| 2004 |
De Angelis M, Katzenellenbogen JA. Ring nitrogen-substituted non-steroidal estrogens: pyridine and pyrimidine analogs of the phenol in deoxyhexestrol experience resonance constraints on preferred ligand conformation. Bioorganic & Medicinal Chemistry Letters. 14: 5835-9. PMID 15501051 DOI: 10.1016/J.Bmcl.2004.09.048 |
0.481 |
|
| 2004 |
Compton DR, Carlson KE, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines as estrogen receptor ligands: defining the orientation of a novel heterocyclic core. Bioorganic & Medicinal Chemistry Letters. 14: 5681-4. PMID 15482947 DOI: 10.1016/J.Bmcl.2004.08.046 |
0.736 |
|
| 2004 |
Mueller SO, Katzenellenbogen JA, Korach KS. Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids. 69: 681-6. PMID 15465114 DOI: 10.1016/J.Steroids.2004.06.004 |
0.469 |
|
| 2004 |
Spera D, Cabrera G, Fiaschi R, Carlson KE, Katzenellenbogen JA, Napolitano E. Estradiol derivatives bearing sulfur-containing substituents at the 11beta or 7alpha positions: versatile reagents for the preparation of estrogen conjugates. Bioorganic & Medicinal Chemistry. 12: 4393-401. PMID 15265491 DOI: 10.1016/J.Bmc.2004.06.017 |
0.424 |
|
| 2004 |
Minutolo F, Antonello M, Bertini S, Placanica G, Rapposelli S, Carlson KE, Katzenellenbogen JA, Macchia M. Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands Farmaco. 59: 601-607. PMID 15262529 DOI: 10.1016/j.farmac.2004.01.007 |
0.424 |
|
| 2004 |
Chen Z, Katzenellenbogen BS, Katzenellenbogen JA, Zhao H. Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity. The Journal of Biological Chemistry. 279: 33855-64. PMID 15159406 DOI: 10.1074/Jbc.M402118200 |
0.515 |
|
| 2004 |
Kim SH, Tamrazi A, Carlson KE, Daniels JR, Lee IY, Katzenellenbogen JA. Estrogen receptor microarrays: subtype-selective ligand binding. Journal of the American Chemical Society. 126: 4754-5. PMID 15080660 DOI: 10.1021/Ja039586Q |
0.811 |
|
| 2004 |
Pedersen SB, Kristensen K, Hermann PA, Katzenellenbogen JA, Richelsen B. Estrogen controls lipolysis by up-regulating α2A-adrenergic receptors directly in human adipose tissue through the estrogen receptor α. Implications for the female fat distribution Journal of Clinical Endocrinology and Metabolism. 89: 1869-1878. PMID 15070958 DOI: 10.1210/Jc.2003-031327 |
0.449 |
|
| 2004 |
Tsai HW, Katzenellenbogen JA, Katzenellenbogen BS, Shupnik MA. Protein kinase A activation of estrogen receptor α transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation Endocrinology. 145: 2730-2738. PMID 15033909 DOI: 10.1210/En.2003-1470 |
0.374 |
|
| 2004 |
Muthyala RS, Ju YH, Sheng S, Williams LD, Doerge DR, Katzenellenbogen BS, Helferich WG, Katzenellenbogen JA. Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry. 12: 1559-67. PMID 15018930 DOI: 10.1016/J.Bmc.2003.11.035 |
0.421 |
|
| 2004 |
Nettles KW, Sun J, Radek JT, Sheng S, Rodriguez AL, Katzenellenbogen JA, Katzenellenbogen BS, Greene GL. Allosteric Control of Ligand Selectivity between Estrogen Receptors α and β: Implications for Other Nuclear Receptors Molecular Cell. 13: 317-327. PMID 14967140 DOI: 10.1016/S1097-2765(04)00054-1 |
0.701 |
|
| 2004 |
Hurth KM, Nilges MJ, Carlson KE, Tamrazi A, Belford RL, Katzenellenbogen JA. Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling. Biochemistry. 43: 1891-907. PMID 14967030 DOI: 10.1021/Bi035566P |
0.827 |
|
| 2004 |
Rodriguez AL, Tamrazi A, Collins ML, Katzenellenbogen JA. Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding. Journal of Medicinal Chemistry. 47: 600-11. PMID 14736241 DOI: 10.1021/Jm030404C |
0.84 |
|
| 2003 |
Muthyala RS, Carlson KE, Katzenellenbogen JA. Exploration of the bicyclo[3.3.1]nonane system as a template for the development of new ligands for the estrogen receptor Bioorganic and Medicinal Chemistry Letters. 13: 4485-4488. PMID 14643352 DOI: 10.1016/J.Bmcl.2003.08.061 |
0.437 |
|
| 2003 |
Tamrazi A, Katzenellenbogen JA. Site-specific fluorescent labeling of estrogen receptors and structure-activity relationships of ligands in terms of receptor dimer stability. Methods in Enzymology. 364: 37-53. PMID 14631838 DOI: 10.1016/S0076-6879(03)64003-6 |
0.815 |
|
| 2003 |
Luyt LG, Bigott HM, Welch MJ, Katzenellenbogen JA. 7alpha- and 17alpha-substituted estrogens containing tridentate tricarbonyl rhenium/technetium complexes: synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m. Bioorganic & Medicinal Chemistry. 11: 4977-89. PMID 14604660 DOI: 10.1016/J.Bmc.2003.09.004 |
0.687 |
|
| 2003 |
Minutolo F, Antonello M, Bertini S, Ortore G, Placanica G, Rapposelli S, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M. Novel estrogen receptor ligands based on an anthranylaldoxime structure: Role of the phenol-type pseudocycle in the binding process Journal of Medicinal Chemistry. 46: 4032-4042. PMID 12954056 DOI: 10.1021/Jm0308390 |
0.436 |
|
| 2003 |
Tamrazi A, Carlson KE, Katzenellenbogen JA. Molecular sensors of estrogen receptor conformations and dynamics. Molecular Endocrinology (Baltimore, Md.). 17: 2593-602. PMID 12947047 DOI: 10.1210/Me.2003-0239 |
0.805 |
|
| 2003 |
Arterburn JB, Corona C, Rao KV, Carlson KE, Katzenellenbogen JA. Synthesis of 17-alpha-substituted estradiol-pyridin-2-yl hydrazine conjugates as effective ligands for labeling with Alberto's complex fac-[Re(OH2)3(CO)3]+ in water. The Journal of Organic Chemistry. 68: 7063-70. PMID 12946150 DOI: 10.1021/Jo034780G |
0.496 |
|
| 2003 |
Harrington WR, Sheng S, Barnett DH, Petz LN, Katzenellenbogen JA, Katzenellenbogen BS. Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. Molecular and Cellular Endocrinology. 206: 13-22. PMID 12943986 DOI: 10.1016/S0303-7207(03)00255-7 |
0.464 |
|
| 2003 |
Lee KC, Moon BS, Lee JH, Chung KH, Katzenellenbogen JA, Chi DY. Synthesis and binding affinities of fluoroalkylated raloxifenes Bioorganic and Medicinal Chemistry. 11: 3649-3658. PMID 12901910 DOI: 10.1016/S0968-0896(03)00362-6 |
0.681 |
|
| 2003 |
Vijaykumar D, Al-Qahtani MH, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a fluorine-18 labeled estrogen receptor-α selective ligand: [18F] propyl pyrazole triol Nuclear Medicine and Biology. 30: 397-404. PMID 12767397 DOI: 10.1016/S0969-8051(02)00446-8 |
0.499 |
|
| 2003 |
Muthyala RS, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor Journal of Medicinal Chemistry. 46: 1589-1602. PMID 12699377 DOI: 10.1021/Jm0204800 |
0.553 |
|
| 2003 |
Minutolo F, Antonello M, Bertini S, Rapposelli S, Rossello A, Sheng S, Carlson KE, Katzenellenbogen JA, Macchia M. Synthesis, binding affinity, and transcriptional activity of hydroxy- and methoxy-substituted 3,4-diarylsalicylaldoximes on estrogen receptors α and β Bioorganic and Medicinal Chemistry. 11: 1247-1257. PMID 12628652 DOI: 10.1016/S0968-0896(02)00640-5 |
0.462 |
|
| 2003 |
Sun J, Katzenellenbogen JA, Zhao H, Katzenellenbogen BS. DNA shuffling method for generating estrogen receptor α and β chimeras in yeast Biotechniques. 34: 278-288. PMID 12613251 DOI: 10.2144/03342St02 |
0.426 |
|
| 2003 |
Wüst F, Carlson KE, Katzenellenbogen JA. Synthesis of novel arylpyrazolo corticosteroids as potential ligands for imaging brain glucocorticoid receptors Steroids. 68: 177-191. PMID 12606009 DOI: 10.1016/S0039-128X(02)00171-X |
0.472 |
|
| 2003 |
Sun J, Baudry J, Katzenellenbogen JA, Katzenellenbogen BS. Molecular basis for the subtype discrimination of the estrogen receptor-β-selective ligand, diarylpropionitrile Molecular Endocrinology. 17: 247-258. PMID 12554752 DOI: 10.1210/Me.2002-0341 |
0.51 |
|
| 2003 |
Ghosh U, Ganessunker D, Sattigeri VJ, Carlson KE, Mortensen DJ, Katzenellenbogen BS, Katzenellenbogen JA. Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes. Bioorganic & Medicinal Chemistry. 11: 629-57. PMID 12538029 DOI: 10.1016/S0968-0896(02)00309-7 |
0.557 |
|
| 2003 |
Katzenellenbogen JA, Muthyala R, Katzenellenbogen BS. The nature of the ligand-binding pocket of estrogen receptor alpha and beta: The search for subtype-selective ligands and implications for the prediction of estrogenic activity Pure and Applied Chemistry. 75: 2397-2403. DOI: 10.1351/Pac200375112397 |
0.524 |
|
| 2003 |
Katzenellenbogen JA, Muthyala R. Interactions of exogenous endocrine active substances with nuclear receptors Pure and Applied Chemistry. 75: 1797-1817. DOI: 10.1351/Pac200375111797 |
0.519 |
|
| 2003 |
Gorshkov NI, Lumpov AA, Miroslavov AE, Suglobov DN, Katzenellenbogen JA, Luyt LG. “Scorpion-like” dithiocarbamato-carboxylate ligands for linking M(CO)3 + (M=Tc, Re) Czechoslovak Journal of Physics. 53: A543-A548. DOI: 10.1007/S10582-003-0070-3 |
0.608 |
|
| 2003 |
Katzenellenbogen JA. Book Review: Steroid Receptor Methods-Protocols and Assays. Edited by Benjamin A. Lieberman Chembiochem. 4: 548-548. DOI: 10.1002/Cbic.200390081 |
0.378 |
|
| 2003 |
Katzenellenbogen JA, Muthyala R, Katzenellenbogen BS. Nature of the ligand-binding pocket of estrogen receptor α and β: The search for subtype-selective ligands and implications for the prediction of estrogenic activity Pure and Applied Chemistry. 75: 2397-2403. |
0.377 |
|
| 2002 |
Tamrazi A, Carlson KE, Daniels JR, Hurth KM, Katzenellenbogen JA. Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate. Molecular Endocrinology (Baltimore, Md.). 16: 2706-19. PMID 12456792 DOI: 10.1210/Me.2002-0250 |
0.845 |
|
| 2002 |
Harris HA, Katzenellenbogen JA, Katzenellenbogen BS. Characterization of the biological roles of the estrogen receptors, ERα and ERβ, in estrogen target tissues in vivo through the use of an ERα-selective ligand Endocrinology. 143: 4172-4177. PMID 12399409 DOI: 10.1210/En.2002-220403 |
0.469 |
|
| 2002 |
Luyt LG, Katzenellenbogen JA. A trithiolate tripodal bifunctional ligand for the radiolabeling of peptides with gallium(III) Bioconjugate Chemistry. 13: 1140-1145. PMID 12236797 DOI: 10.1021/Bc025552G |
0.626 |
|
| 2002 |
Vijaykumar D, Mao W, Kirschbaum KS, Katzenellenbogen JA. An efficient route for the preparation of a 21-fluoro progestin-16 alpha,17 alpha-dioxolane, a high-affinity ligand for PET imaging of the progesterone receptor. The Journal of Organic Chemistry. 67: 4904-10. PMID 12098304 DOI: 10.1021/Jo020190R |
0.405 |
|
| 2002 |
Nishiguchi GA, Rodriguez AL, Katzenellenbogen JA. Diaryl-dialkyl-substituted pyrazoles: regioselective synthesis and binding affinity for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 12: 947-50. PMID 11959000 DOI: 10.1016/S0960-894X(02)00057-4 |
0.671 |
|
| 2002 |
Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nature Structural Biology. 9: 359-64. PMID 11953755 DOI: 10.1038/Nsb787 |
0.71 |
|
| 2002 |
Rickard DJ, Waters KM, Ruesink TJ, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Riggs BL, Spelsberg TC. Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts Journal of Bone and Mineral Research. 17: 580-592. PMID 11918216 DOI: 10.1359/Jbmr.2002.17.4.580 |
0.413 |
|
| 2002 |
Mull ES, Sattigeri VJ, Rodriguez AL, Katzenellenbogen JA. Aryl cyclopentadienyl tricarbonyl rhenium complexes: novel ligands for the estrogen receptor with potential use as estrogen radiopharmaceuticals. Bioorganic & Medicinal Chemistry. 10: 1381-98. PMID 11886802 DOI: 10.1016/S0968-0896(01)00406-0 |
0.716 |
|
| 2002 |
Sun J, Huang YR, Harrington WR, Sheng S, Katzenellenbogen JA, Katzenellenbogen BS. Antagonists selective for estrogen receptor alpha. Endocrinology. 143: 941-7. PMID 11861516 DOI: 10.1210/Endo.143.3.8704 |
0.401 |
|
| 2002 |
Katzenellenbogen BS, Sun J, Harrington WR, Kraichely DM, Ganessunker D, Katzenellenbogen JA. Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles. Annals of the New York Academy of Sciences. 949: 6-15. PMID 11795381 DOI: 10.1111/J.1749-6632.2001.Tb03998.X |
0.522 |
|
| 2002 |
Cesati RR, Tamagnan G, Baldwin RM, Zoghbi SS, Innis RB, Kula NS, Baldessarini RJ, Katzenellenbogen JA. Synthesis of cyclopentadienyltricarbonyl rhenium phenyltropanes by double ligand transfer: organometallic ligands for the dopamine transporter. Bioconjugate Chemistry. 13: 29-39. PMID 11792176 DOI: 10.1021/Bc010011X |
0.75 |
|
| 2001 |
Minutolo F, Bertini S, Papi C, Carlson KE, Katzenellenbogen JA, Macchia M. Salicylaldoxime moiety as a phenolic "A-Ring" substitute in estrogen receptor ligands. Journal of Medicinal Chemistry. 44: 4288-91. PMID 11708930 DOI: 10.1021/Jm010948J |
0.519 |
|
| 2001 |
Meyers MJ, Sun J, Carlson KE, Marriner GA, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. Journal of Medicinal Chemistry. 44: 4230-51. PMID 11708925 DOI: 10.1021/Jm010254A |
0.73 |
|
| 2001 |
Mortensen DS, Rodriguez AL, Carlson KE, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Synthesis and biological evaluation of a novel series of furans: ligands selective for estrogen receptor alpha. Journal of Medicinal Chemistry. 44: 3838-48. PMID 11689070 DOI: 10.1021/Jm010211U |
0.848 |
|
| 2001 |
Waters KM, Rickard DJ, Lawrence Riggs B, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Moore J, Spelsberg TC. Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform Journal of Cellular Biochemistry. 83: 448-462. PMID 11596113 DOI: 10.1002/Jcb.1242 |
0.34 |
|
| 2001 |
Nuedling S, Karas RH, Mendelsohn ME, Katzenellenbogen JA, Katzenellenbogen BS, Meyer R, Vetter H, Grohé C. Activation of estrogen receptor β is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytes Febs Letters. 502: 103-108. PMID 11583108 DOI: 10.1016/S0014-5793(01)02675-8 |
0.312 |
|
| 2001 |
Mortensen DS, Rodriguez AL, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha. Bioorganic & Medicinal Chemistry Letters. 11: 2521-4. PMID 11549460 DOI: 10.1016/S0960-894X(01)00488-7 |
0.835 |
|
| 2001 |
Downer JB, Jones LA, Engelbach JA, Lich LL, Mao W, Carlson KE, Katzenellenbogen JA, Welch MJ. Comparison of animal models for the evaluation of radiolabeled androgens. Nuclear Medicine and Biology. 28: 613-26. PMID 11518642 DOI: 10.1016/S0969-8051(01)00229-3 |
0.328 |
|
| 2001 |
Cesati RR, Katzenellenbogen JA. One-pot formation of substituted cyclopentadienyl and indenyltricarbonyl rhenium complexes through in situ generation of cyclopentadienyl- and indenyltributylstannanes. Journal of the American Chemical Society. 123: 4093-4. PMID 11457166 DOI: 10.1021/Ja005585B |
0.697 |
|
| 2001 |
Tedesco R, Youngman MK, Wilson SR, Katzenellenbogen JA. Synthesis and evaluation of hexahydrochrysene and tetrahydrobenzofluorene ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 11: 1281-4. PMID 11392537 DOI: 10.1016/S0960-894X(01)00189-5 |
0.711 |
|
| 2001 |
Mortimer JE, Dehdashti F, Siegel BA, Trinkaus K, Katzenellenbogen JA, Welch MJ. Metabolic flare: indicator of hormone responsiveness in advanced breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2797-803. PMID 11387350 DOI: 10.1200/Jco.2001.19.11.2797 |
0.355 |
|
| 2001 |
Kim SH, Jonson SD, Welch MJ, Katzenellenbogen JA. Fluorine-substituted ligands for the peroxisome proliferator-activated receptor gamma (PPARgamma): potential imaging agents for metastatic tumors. Bioconjugate Chemistry. 12: 439-50. PMID 11353543 DOI: 10.1021/Bc000153B |
0.417 |
|
| 2001 |
Tedesco R, Thomas JA, Katzenellenbogen BS, Katzenellenbogen JA. The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations. Chemistry & Biology. 8: 277-87. PMID 11306352 DOI: 10.1016/S1074-5521(01)00006-0 |
0.741 |
|
| 2001 |
Gee AC, Katzenellenbogen JA. Probing conformational changes in the estrogen receptor: evidence for a partially unfolded intermediate facilitating ligand binding and release. Molecular Endocrinology (Baltimore, Md.). 15: 421-8. PMID 11222743 DOI: 10.1210/Mend.15.3.0602 |
0.811 |
|
| 2001 |
Stauffer SR, Huang YR, Aron ZD, Coletta CJ, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists. Bioorganic & Medicinal Chemistry. 9: 151-61. PMID 11197335 DOI: 10.1016/S0968-0896(00)00226-1 |
0.512 |
|
| 2001 |
Stauffer SR, Huang Y, Coletta CJ, Tedesco R, Katzenellenbogen JA. Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor. Bioorganic & Medicinal Chemistry. 9: 141-50. PMID 11197334 DOI: 10.1016/S0968-0896(00)00228-5 |
0.709 |
|
| 2001 |
Kousteni S, Bellido T, Plotkin L, O'Brien C, Bodenner D, Han L, Han K, DiGregorio G, Katzenellenbogen J, Katzenellenbogen B, Roberson P, Weinstein R, Jilka R, Manolagas S. Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors Cell. 104: 719-730. DOI: 10.1016/S0092-8674(01)00268-9 |
0.512 |
|
| 2001 |
Luyt LG, Katzenellenbogen JA. Synthesis of a functionalized gallium(III) tripodyl complex Journal of Labelled Compounds and Radiopharmaceuticals. 44: S773-S774. DOI: 10.1002/Jlcr.25804401272 |
0.595 |
|
| 2001 |
Mull ES, Katzenellenbogen JA. Development of cyclopentadienyl tricarbonyl metal complexes as radiopharmaceuticals for the estrogen receptor using an “integrated” design Journal of Labelled Compounds and Radiopharmaceuticals. 44: S69-S71. DOI: 10.1002/Jlcr.2580440124 |
0.391 |
|
| 2001 |
Luyt LG, Mull ES, Katzenellenbogen JA, Bigott HM, Welch MJ. Preparation of cyclopentadienyl tricarbonyl technetium-94m complexes Journal of Labelled Compounds and Radiopharmaceuticals. 44: S489-S490. DOI: 10.1002/Jlcr.25804401173 |
0.586 |
|
| 2001 |
Gorshkov NI, Katzenellenbogen JA, Luyt LG, Lumpov AA, Miroslavov AE, Suglobov DN. New dithiocarbamato-carboxylate chelation units for linking M(CO)3+ (M = Tc, Re) species to other molecules Journal of Labelled Compounds and Radiopharmaceuticals. 44: S486-S488. DOI: 10.1002/Jlcr.25804401172 |
0.565 |
|
| 2001 |
Vijaykumar D, Katzenellenbogen JA. Halogen-substituted triarylpyrazoles: Potential estrogen receptor-alpha selective radiopharmaceuticals Journal of Labelled Compounds and Radiopharmaceuticals. 44: S342-S344. DOI: 10.1002/Jlcr.25804401120 |
0.513 |
|
| 2001 |
Kim SH, Jonson SD, Welch MJ, Katzenellenbogen JA. Fluorine-substituted ligands for the peroxisome proliferator-activated receptor gamma (Pparγ): Potential imaging agents for metastatic tumors Journal of Labelled Compounds and Radiopharmaceuticals. 44: S316-S318. DOI: 10.1002/Jlcr.25804401111 |
0.481 |
|
| 2000 |
Kraichely DM, Sun J, Katzenellenbogen JA, Katzenellenbogen BS. Conformational Changes and Coactivator Recruitment by Novel Ligands for Estrogen Receptor-α and Estrogen Receptor-β: Correlations with Biological Character and Distinct Differences among SRC Coactivator Family Members. Endocrinology. 141: 3534-3545. PMID 28200959 DOI: 10.1210/endo.141.10.7698 |
0.342 |
|
| 2000 |
Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor alpha and estrogen receptor beta: Regulation by selective estrogen receptor modulators and importance in breast cancer Breast Cancer Research. 2: 335-344. PMID 11250726 DOI: 10.1186/Bcr78 |
0.507 |
|
| 2000 |
Katzenellenbogen BS, Choi I, Delage-Mourroux R, Ediger TR, Martini PG, Montano M, Sun J, Weis K, Katzenellenbogen JA. Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. The Journal of Steroid Biochemistry and Molecular Biology. 74: 279-85. PMID 11162936 DOI: 10.1016/S0960-0760(00)00104-7 |
0.513 |
|
| 2000 |
Stauffer SR, Coletta CJ, Tedesco R, Nishiguchi G, Carlson K, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. Journal of Medicinal Chemistry. 43: 4934-47. PMID 11150164 DOI: 10.1021/Jm000170M |
0.737 |
|
| 2000 |
Cesati RR, Katzenellenbogen JA. Preparation of hexahydrobenzo[f]isoquinolines using a vinylogous pictet-spengler cyclization. Organic Letters. 2: 3635-8. PMID 11073663 |
0.7 |
|
| 2000 |
Ju YH, Carlson KE, Sun J, Pathak D, Katzenellenbogen BS, Katzenellenbogen JA, Helferich WG. Estrogenic effects of extracts from cabbage, fermented cabbage, and acidified brussels sprouts on growth and gene expression of estrogen-dependent human breast cancer (MCF-7) cells. Journal of Agricultural and Food Chemistry. 48: 4628-34. PMID 11052710 DOI: 10.1021/Jf000164Z |
0.388 |
|
| 2000 |
Kraichely DM, Sun J, Katzenellenbogen JA, Katzenellenbogen BS. Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-α and estrogen receptor-β: Correlations with biological character and distinct differences among SRC coactivator family members Endocrinology. 141: 3534-3545. PMID 11014206 DOI: 10.1210/Endo.141.10.7698 |
0.543 |
|
| 2000 |
Huang YR, Katzenellenbogen JA. Regioselective synthesis of 1,3,5-triaryl-4-alkylpyrazoles: novel ligands for the estrogen receptor. Organic Letters. 2: 2833-6. PMID 10964377 DOI: 10.1021/OL0062650 |
0.411 |
|
| 2000 |
Stauffer SR, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Acyclic amides as estrogen receptor ligands: Synthesis, binding, activity and receptor interaction Bioorganic and Medicinal Chemistry. 8: 1293-1316. PMID 10896109 DOI: 10.1016/S0968-0896(00)00075-4 |
0.507 |
|
| 2000 |
Stauffer SR, Katzenellenbogen JA. Solid-phase synthesis of tetrasubstituted pyrazoles, novel ligands for the estrogen receptor. Journal of Combinatorial Chemistry. 2: 318-29. PMID 10891098 DOI: 10.1021/CC0000040 |
0.402 |
|
| 2000 |
Skaddan MB, Wüst FR, Jonson S, Syhre R, Welch MJ, Spies H, Katzenellenbogen JA. Radiochemical synthesis and tissue distribution of Tc-99m-labeled 7alpha-substituted estradiol complexes. Nuclear Medicine and Biology. 27: 269-78. PMID 10832084 DOI: 10.1016/S0969-8051(00)00083-4 |
0.781 |
|
| 2000 |
Kim SH, Katzenellenbogen JA. Triarylethylene bisphenols with a novel cycle are ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry. 8: 785-93. PMID 10819167 DOI: 10.1016/S0968-0896(00)00016-X |
0.543 |
|
| 2000 |
Huang YR, Katzenellenbogen JA. ChemInform Abstract: Regioselective Synthesis of 1,3,5-Triaryl-4-alkylpyrazoles: Novel Ligands for the Estrogen Receptor. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200052105 |
0.429 |
|
| 1999 |
Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS. Novel Ligands that Function as Selective Estrogens or Antiestrogens for Estrogen Receptor-α or Estrogen Receptor-β. Endocrinology. 140: 800-804. PMID 28204395 DOI: 10.1210/endo.140.2.6480 |
0.709 |
|
| 1999 |
Gao H, Katzenellenbogen JA, Garg R, Hansch C. Comparative QSAR analysis of estrogen receptor ligands. Chemical Reviews. 99: 723-44. PMID 11749430 DOI: 10.1021/Cr980018G |
0.505 |
|
| 1999 |
Gee AC, Carlson KE, Martini PG, Katzenellenbogen BS, Katzenellenbogen JA. Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 13: 1912-23. PMID 10551784 DOI: 10.1210/Mend.13.11.0373 |
0.824 |
|
| 1999 |
Wüst F, Skaddan MB, Leibnitz P, Spies H, Katzenellenbogen JA, Johannsen B. Synthesis of novel progestin-rhenium conjugates as potential ligands for the progesterone receptor Bioorganic and Medicinal Chemistry. 7: 1827-1835. PMID 10530930 DOI: 10.1016/S0968-0896(99)00119-4 |
0.805 |
|
| 1999 |
Meyers MJ, Sun J, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes. Journal of Medicinal Chemistry. 42: 2456-68. PMID 10395487 DOI: 10.1021/Jm990101B |
0.719 |
|
| 1999 |
Fink BE, Mortensen DS, Stauffer SR, Aron ZD, Katzenellenbogen JA. Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens. Chemistry & Biology. 6: 205-19. PMID 10099132 DOI: 10.1016/S1074-5521(99)80037-4 |
0.824 |
|
| 1999 |
Jonson SD, Bonasera TA, Dehdashti F, Cristel ME, Katzenellenbogen JA, Welch MJ. Comparative breast tumor imaging and comparative in vitro metabolism of 16alpha-[18F]fluoroestradiol-17beta and 16beta-[18F]fluoromoxestrol in isolated hepatocytes. Nuclear Medicine and Biology. 26: 123-30. PMID 10096512 DOI: 10.1016/S0969-8051(98)00079-1 |
0.318 |
|
| 1999 |
Spradau TW, Edwards WB, Anderson CJ, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricarbonyltechnetium-labeled octreotide. Nuclear Medicine and Biology. 26: 1-7. PMID 10096494 DOI: 10.1016/S0969-8051(98)00060-2 |
0.316 |
|
| 1999 |
Dehdashti F, Flanagan FL, Mortimer JE, Katzenellenbogen JA, Welch MJ, Siegel BA. Positron emission tomographic assessment of "metabolic flare" to predict response of metastatic breast cancer to antiestrogen therapy. European Journal of Nuclear Medicine. 26: 51-6. PMID 9933662 DOI: 10.1007/S002590050359 |
0.312 |
|
| 1999 |
Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology. 140: 800-4. PMID 9927308 DOI: 10.1210/Endo.140.2.6480 |
0.712 |
|
| 1999 |
Skaddan MB, Katzenellenbogen JA. Integrated "3+1" oxorhenium(V) complexes as estrogen mimics. Bioconjugate Chemistry. 10: 119-29. PMID 9893973 DOI: 10.1021/Bc980094Q |
0.797 |
|
| 1999 |
Spradau TW, Katzenellenbogen JA. Ligands for the estrogen receptor, containing cyclopentadienyltricarbonylrhenium units. Bioorganic & Medicinal Chemistry Letters. 8: 3235-40. PMID 9873709 DOI: 10.1016/S0960-894X(98)00592-7 |
0.449 |
|
| 1998 |
Meyers MJ, Carlson KE, Katzenellenbogen JA. Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 8: 3589-94. PMID 9934476 DOI: 10.1016/S0960-894X(98)00652-0 |
0.711 |
|
| 1998 |
Wüst F, Carlson KE, Katzenellenbogen JA, Spies H, Johannsen B. Synthesis and binding affinities of new 17α-substituted estradiol- rhenium 'n+1' mixed-ligand and thioether-carbonyl complexes Steroids. 63: 665-671. PMID 9870263 DOI: 10.1016/S0039-128X(98)00079-8 |
0.477 |
|
| 1998 |
Jonson SD, d'Avignon DA, Katzenellenbogen JA, Welch MJ. Methyl hypofluorite in the synthesis of 16-methoxyestradiol stereoisomers. Steroids. 63: 470-8. PMID 9727094 DOI: 10.1016/S0039-128X(98)00051-8 |
0.436 |
|
| 1998 |
Ekena K, Katzenellenbogen JA, Katzenellenbogen BS. Determinants of ligand specificity of estrogen receptor-α: Estrogen versus androgen discrimination Journal of Biological Chemistry. 273: 693-699. PMID 9422719 DOI: 10.1074/Jbc.273.2.693 |
0.532 |
|
| 1998 |
Hom RK, Katzenellenbogen JA. Technetium-99m-labeled receptor-specific small-molecule radiopharmaceuticals: recent developments and encouraging results. Nuclear Medicine and Biology. 24: 485-98. PMID 9316075 DOI: 10.1016/S0969-8051(97)00066-8 |
0.419 |
|
| 1998 |
Chesnut RW, Cesati RR, Cutler CS, Pluth SL, Katzenellenbogen JA. Four-coordinate dimethylgallium compounds vary in stability toward hydrolysis Organometallics. 17: 4889-4896. DOI: 10.1021/Om980413X |
0.749 |
|
| 1998 |
Spradau TW, Katzenellenbogen JA. Preparation of Cyclopentadienyltricarbonylrhenium Complexes Using a Double Ligand-Transfer Reaction Organometallics. 17: 2009-2017. DOI: 10.1021/Om971018U |
0.337 |
|
| 1997 |
Carlson KE, Choi I, Gee A, Katzenellenbogen BS, Katzenellenbogen JA. Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: Evidence that an open pocket conformation is required for ligand interaction Biochemistry. 36: 14897-14905. PMID 9398213 DOI: 10.1021/Bi971746L |
0.816 |
|
| 1997 |
Cushman M, He HM, Katzenellenbogen JA, Varma RK, Hamel E, Lin CM, Ram S, Sachdeva YP. Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth. Journal of Medicinal Chemistry. 40: 2323-34. PMID 9240348 DOI: 10.1021/Jm9700833 |
0.374 |
|
| 1997 |
Bergmann KE, Landvatter SW, Rocque PG, Carlson KE, Welch MJ, Katzenellenbogen JA. Oxohexestrol derivatives labeled with fluorine-18. Synthesis, receptor binding and in vivo distribution of two non-steroidal estrogens as potential breast tumor imaging agents. Nuclear Medicine and Biology. 21: 25-39. PMID 9234261 DOI: 10.1016/0969-8051(94)90126-0 |
0.483 |
|
| 1997 |
Scribner AW, Jonson SD, Welch MJ, Katzenellenbogen JA. Synthesis, estrogen receptor binding, and tissue distribution of [18F]fluorodoisynolic acids. Nuclear Medicine and Biology. 24: 209-24. PMID 9228655 DOI: 10.1016/S0969-8051(97)00058-9 |
0.403 |
|
| 1997 |
Anstead GM, Carlson KE, Katzenellenbogen JA. The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site Steroids. 62: 268-303. PMID 9071738 DOI: 10.1016/S0039-128X(96)00242-5 |
0.497 |
|
| 1997 |
Ekena K, Weis KE, Katzenellenbogen JA, Katzenellenbogen BS. Different residues of the human estrogen receptor are involved in the recognition of structurally diverse estrogens and antiestrogens. The Journal of Biological Chemistry. 272: 5069-75. PMID 9030571 DOI: 10.1074/Jbc.272.8.5069 |
0.506 |
|
| 1997 |
Kym PR, Hummert KL, Nilsson AG, Lubin M, Katzenellenbogen JA. Bisphenolic compounds that enhance cell cation transport are found in commercial phenol red. Journal of Medicinal Chemistry. 39: 4897-904. PMID 8960548 DOI: 10.1021/Jm960300K |
0.304 |
|
| 1997 |
Dence CS, Napolitano E, Katzenellenbogen JA, Welch MJ. Carbon-11-labeled estrogens as potential imaging agents for breast tumors. Nuclear Medicine and Biology. 23: 491-6. PMID 8832705 DOI: 10.1016/0969-8051(96)00029-7 |
0.413 |
|
| 1997 |
Bowen CM, Katzenellenbogen JA. Synthesis and Spectroscopic Characterization of Two Azatetrahydrochrysenes as Potential Fluorescent Ligands for the Estrogen Receptor The Journal of Organic Chemistry. 62: 7650-7657. DOI: 10.1021/Jo9708405 |
0.384 |
|
| 1997 |
Scribner AW, Haroutounian SA, Carlson KE, Katzenellenbogen JA. 1-Aryl-2-pyridyl-3,4-dihydronaphthalenes: Photofluorogenic Ligands for the Estrogen Receptor The Journal of Organic Chemistry. 62: 1043-1057. DOI: 10.1021/Jo9618029 |
0.491 |
|
| 1997 |
Tedesco R, Katzenellenbogen JA, Napolitano E. 7α,11β-Disubstituted estrogens: Probes for the shape of the ligand binding pocket in the estrogen receptor Bioorganic & Medicinal Chemistry Letters. 7: 2919-2924. DOI: 10.1016/S0960-894X(97)10099-3 |
0.633 |
|
| 1997 |
Tedesco R, Katzenellenbogen JA, Napolitano E. AN EXPEDITIOUS ROUTE TO 7α-SUBSTITUTED ESTRADIOL DERIVATIVES Tetrahedron Letters. 38: 7997-8000. DOI: 10.1016/S0040-4039(97)10180-0 |
0.575 |
|
| 1996 |
Katzenellenbogen JA, O'Malley BW, Katzenellenbogen BS. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones Molecular Endocrinology. 10: 119-131. PMID 8825552 DOI: 10.1210/Mend.10.2.8825552 |
0.412 |
|
| 1996 |
Katzenellenbogen JA, Katzenellenbogen BS. Nuclear hormone receptors: Ligand-activated regulators of transcription and diverse cell responses Chemistry and Biology. 3: 529-536. PMID 8807884 DOI: 10.1016/S1074-5521(96)90143-X |
0.359 |
|
| 1996 |
Devraj R, Barrett JF, Fernandez JA, Katzenellenbogen JA, Cushman M. Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates. Journal of Medicinal Chemistry. 39: 3367-74. PMID 8765520 DOI: 10.1021/Jm9602930 |
0.492 |
|
| 1996 |
Ekena K, Weis KE, Katzenellenbogen JA, Katzenellenbogen BS. Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding. The Journal of Biological Chemistry. 271: 20053-9. PMID 8702724 DOI: 10.1074/Jbc.271.33.20053 |
0.511 |
|
| 1996 |
Haroutounian SA, Scribner AW, Katzenellenbogen JA. Derivatives of 4-styrylpyridines: synthesis, estrogen receptor binding affinity, and photophysical properties. Steroids. 60: 636-45. PMID 8545854 DOI: 10.1016/0039-128X(95)00072-X |
0.507 |
|
| 1996 |
Srivastava N, Ray S, Dwivedy I, Wilson SR, Hom RK, Katzenellenbogen JA. Determination of the absolute configuration of the nonsteroidal contraceptive agent centchroman by X-ray crystallography on its N-methyl iodide salt Bioorganic & Medicinal Chemistry Letters. 6: 1747-1752. DOI: 10.1016/0960-894X(96)00309-5 |
0.343 |
|
| 1996 |
Sugano Y, Katzenellenbogen JA. Synthesis of tetradentate bisamino-bisthiol complexes of oxorhenium(V) as structural mimics of steroids Bioorganic & Medicinal Chemistry Letters. 6: 361-366. DOI: 10.1016/0960-894X(96)00029-7 |
0.303 |
|
| 1995 |
Seielstad DA, Carlson KE, Katzenellenbogen JA, Kushner PJ, Greene GL. Molecular characterization by mass spectrometry of the human estrogen receptor ligand-binding domain expressed in Escherichia coli. Molecular Endocrinology (Baltimore, Md.). 9: 647-58. PMID 8592511 DOI: 10.1210/Mend.9.6.8592511 |
0.386 |
|
| 1995 |
Choe YS, Lidström PJ, Chi DY, Bonasera TA, Welch MJ, Katzenellenbogen JA. Synthesis of 11 beta-[18F]fluoro-5 alpha-dihydrotestosterone and 11 beta-[18F]fluoro-19-nor-5 alpha-dihydrotestosterone: preparation via halofluorination-reduction, receptor binding, and tissue distribution. Journal of Medicinal Chemistry. 38: 816-25. PMID 7877147 DOI: 10.1021/Jm00005A009 |
0.579 |
|
| 1995 |
Napolitano E, Fiaschi R, Carlson KE, Katzenellenbogen JA. 11 beta-Substituted estradiol derivatives, potential high-affinity carbon-11-labeled probes for the estrogen receptor: a structure-affinity relationship study. Journal of Medicinal Chemistry. 38: 429-34. PMID 7853335 DOI: 10.1021/Jm00003A005 |
0.356 |
|
| 1995 |
Buckman BO, Bonasera TA, Kirschbaum KS, Welch MJ, Katzenellenbogen JA. Fluorine-18-labeled progestin 16 alpha, 17 alpha-dioxolanes: development of high-affinity ligands for the progesterone receptor with high in vivo target site selectivity. Journal of Medicinal Chemistry. 38: 328-37. PMID 7830275 DOI: 10.1021/Jm00002A014 |
0.405 |
|
| 1995 |
Chi DY, Wilson SR, Katzenellenbogen JA. Crystal structure of doisynolic acid and the structure of other products formed during its synthesis. Steroids. 60: 261-4. PMID 7792828 DOI: 10.1016/0039-128X(94)00051-D |
0.531 |
|
| 1995 |
Cushman M, He HM, Katzenellenbogen JA, Lin CM, Hamel E. Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site. Journal of Medicinal Chemistry. 38: 2041-9. PMID 7783135 DOI: 10.1021/Jm00012A003 |
0.42 |
|
| 1995 |
Napolitano E, Fiaschi R, Carlson KE, Katzenellenbogen JA. 11 beta-substituted estradiol derivatives. 2. Potential carbon-11- and iodine-labeled probes for the estrogen receptor. Journal of Medicinal Chemistry. 38: 2774-9. PMID 7629815 DOI: 10.1021/Jm00014A028 |
0.498 |
|
| 1995 |
Choe YS, Bonasera TA, Chi DY, Welch MJ, Katzenellenbogen JA. 6 alpha-[18F]fluoroprogesterone: synthesis via halofluorination-oxidation, receptor binding and tissue distribution. Nuclear Medicine and Biology. 22: 635-42. PMID 7581174 DOI: 10.1016/0969-8051(94)00142-7 |
0.632 |
|
| 1995 |
Choe YS, Katzenellenbogen JA. Synthesis of C-6 fluoroandrogens: Evaluation of ligands for tumor receptor imaging Steroids. 60: 414-422. PMID 7570716 DOI: 10.1016/0039-128X(95)00009-F |
0.461 |
|
| 1995 |
Miksicek RJ, Carlson KE, Hwang KJ, Katzenellenbogen JA. Studies using fluorescent tetrahydrochrysene estrogens for in situ visualization of the estrogen receptor in living cells. Molecular Endocrinology (Baltimore, Md.). 9: 592-604. PMID 7565806 DOI: 10.1210/Mend.9.5.7565806 |
0.358 |
|
| 1995 |
Seielstad DA, Carlson KE, Kushner PJ, Greene GL, Katzenellenbogen JA. Analysis of the structural core of the human estrogen receptor ligand binding domain by selective proteolysis/mass spectrometric analysis. Biochemistry. 34: 12605-15. PMID 7548010 DOI: 10.1021/Bi00039A016 |
0.4 |
|
| 1995 |
Chi DY, Wilson SR, Katzenellenbogen JA. Crystal Structure of a Bis(amido)bis(thiolato)oxorhenium(V) Complex That Forms a Methanol-Solvated Salt with Calcium Extracted from Silica Gel Inorganic Chemistry. 34: 1624-1625. DOI: 10.1021/Ic00110A048 |
0.529 |
|
| 1995 |
Chi DY, Lidström PJ, Choe YS, Bonasera TA, Welch MJ, Katzenellenbogen JA. Bromo[18F]fluorination of cyclohexenes: a method for the preparation of [18F]fluorocyclohexanes Journal of Fluorine Chemistry. 71: 143-147. DOI: 10.1016/0022-1139(94)03172-V |
0.534 |
|
| 1994 |
Chi DY, O'Neil JP, Anderson CJ, Welch MJ, Katzenellenbogen JA. Homodimeric and heterodimeric bis(amino thiol) oxometal complexes with rhenium(V) and technetium(V). Control of heterodimeric complex formation and an approach to metal complexes that mimic steroid hormones. Journal of Medicinal Chemistry. 37: 928-37. PMID 8151620 DOI: 10.1021/Jm00033A010 |
0.583 |
|
| 1994 |
VanBrocklin HF, Liu A, Welch MJ, O'Neil JP, Katzenellenbogen JA. The synthesis of 7 alpha-methyl-substituted estrogens labeled with fluorine-18: potential breast tumor imaging agents. Steroids. 59: 34-45. PMID 8140600 DOI: 10.1016/0039-128X(94)90043-4 |
0.49 |
|
| 1994 |
Bergmann KE, Carlson KE, Katzenellenbogen JA. Hexestrol diazirine photoaffinity labeling reagent for the estrogen receptor. Bioconjugate Chemistry. 5: 141-50. PMID 8031877 DOI: 10.1021/Bc00026A006 |
0.459 |
|
| 1994 |
Bergmann KE, Wooge CH, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bivalent ligands as probes of estrogen receptor action Journal of Steroid Biochemistry and Molecular Biology. 49: 139-152. PMID 8031710 DOI: 10.1016/0960-0760(94)90004-3 |
0.523 |
|
| 1994 |
O'Neil JP, Carlson KE, Anderson CJ, Welch MJ, Katzenellenbogen JA. Progestin radiopharmaceuticals labeled with technetium and rhenium: synthesis, binding affinity, and in vivo distribution of a new progestin N2S2-metal conjugate. Bioconjugate Chemistry. 5: 182-93. PMID 7918738 DOI: 10.1021/Bc00027A002 |
0.448 |
|
| 1993 |
Anstead GM, Hwang KJ, Katzenellenbogen JA. Characterization of the spectroscopic properties of a tetrahydrochrysene system containing a rigidified hydroxynitrostilbene chromophore: an inherently fluorescent ligand designed for the estrogen receptor. Photochemistry and Photobiology. 57: 616-628. PMID 8506389 DOI: 10.1111/J.1751-1097.1993.Tb02927.X |
0.31 |
|
| 1993 |
Kochanny MJ, VanBrocklin HF, Kym PR, Carlson KE, O'Neil JP, Bonasera TA, Welch MJ, Katzenellenbogen JA. Fluorine-18-labeled progestin ketals: synthesis and target tissue uptake selectivity of potential imaging agents for receptor-positive breast tumors. Journal of Medicinal Chemistry. 36: 1120-7. PMID 8487253 DOI: 10.1021/Jm00061A002 |
0.447 |
|
| 1993 |
French AN, Napolitano E, Vanbrocklin HF, Hanson RN, Welch MJ, Katzenellenbogen JA. Synthesis, radiolabeling and tissue distribution of 11β-fluoroalkyl- and 11β-fluoroalkoxy-substituted estrogens: Target tissue uptake selectivity and defluorination of a homologous series of fluorine-18-labeled estrogens Nuclear Medicine and Biology. 20: 31-47. PMID 8461878 DOI: 10.1016/0969-8051(93)90134-G |
0.456 |
|
| 1993 |
Katzenellenbogen JA, Mathias CJ, VanBrocklin HF, Brodack JW, Welch MJ. Titration of the in vivo uptake of 16 alpha-[18F]fluoroestradiol by target tissues in the rat: competition by tamoxifen, and implications for quantitating estrogen receptors in vivo and the use of animal models in receptor-binding radiopharmaceutical development. Nuclear Medicine and Biology. 20: 735-45. PMID 8401374 DOI: 10.1016/0969-8051(93)90160-V |
0.413 |
|
| 1993 |
Kym PR, Carlson KE, Katzenellenbogen JA. Progestin 16 alpha, 17 alpha-dioxolane ketals as molecular probes for the progesterone receptor: synthesis, binding affinity, and photochemical evaluation. Journal of Medicinal Chemistry. 36: 1111-9. PMID 8387596 DOI: 10.1021/Jm00061A001 |
0.504 |
|
| 1993 |
VanBrocklin HF, Rocque PA, Lee HV, Carlson KE, Katzenellenbogen JA, Welch MJ. 16 beta-[18F]fluoromoxestrol: a potent, metabolically stable positron emission tomography imaging agent for estrogen receptor positive human breast tumors. Life Sciences. 53: 811-9. PMID 8355567 DOI: 10.1016/0024-3205(93)90503-U |
0.379 |
|
| 1993 |
Kym PR, Anstead GM, Pinney KG, Wilson SR, Katzenellenbogen JA. Molecular structures, conformational analysis, and preferential modes of binding of 3-aroyl-2-arylbenzo[b]thiophene estrogen receptor ligands: LY117018 and aryl azide photoaffinity labeling analogs. Journal of Medicinal Chemistry. 36: 3910-22. PMID 8254621 DOI: 10.1021/Jm00076A020 |
0.686 |
|
| 1993 |
Goldstein RA, Katzenellenbogen JA, Luthey-Schulten ZA, Seielstad DA, Wolynes PG. Three-dimensional model for the hormone binding domains of steroid receptors. Proceedings of the National Academy of Sciences of the United States of America. 90: 9949-53. PMID 8234340 DOI: 10.1073/Pnas.90.21.9949 |
0.458 |
|
| 1993 |
VanBrocklin HF, Carlson KE, Katzenellenbogen JA, Welch MJ. 16 beta-([18F]fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors. Journal of Medicinal Chemistry. 36: 1619-29. PMID 7684451 DOI: 10.1021/Jm00063A012 |
0.381 |
|
| 1993 |
Chi DY, Katzenellenbogen JA. Selective formation of heterodimeric bis-bidentate aminothiol-oxometal complexes or rhenium(V) Journal of the American Chemical Society. 115: 7045-7046. DOI: 10.1021/Ja00068A101 |
0.54 |
|
| 1993 |
French AN, Wilson SR, Welch MJ, Katzenellenbogen JA. A synthesis of 7α-substituted estradiols: synthesis and biological evaluation of a 7α-pentyl-substituted BODIPY fluorescent conjugate and a fluorine-18-labeled 7α-pentylestradiol analog Steroids. 58: 157-169. DOI: 10.1016/0039-128X(93)90063-S |
0.389 |
|
| 1993 |
Kochanny MJ, Härd T, Katzenellenbogen JA. Synthesis and NMR spectrum of [13C18]-meso-hexestrol, a fully carbon-13 substituted ligand for NMR studies of the estrogen receptor Magnetic Resonance in Chemistry. 31: 977-986. DOI: 10.1002/Mrc.1260311105 |
0.394 |
|
| 1992 |
Vanbrocklin HF, Pomper MG, Carlson KE, Welch MJ, Katzenellenbogen JA. Preparation and evaluation of 17-ethynyl-substituted 16α-[18F]fluoroestradiols: Selective receptor-based PET imaging agents Nuclear Medicine and Biology. 19: 363-374. PMID 1629026 DOI: 10.1016/0883-2897(92)90122-F |
0.493 |
|
| 1992 |
DiZio JP, Carlson KE, Bannochie CJ, Welch MJ, Von Angerer E, Katzenellenbogen JA. Estrogen platinum-diamine complexes: preparation of a non-steroidal estrogen platinum-diamine complex labeled with platinum-191 and a study of its binding to the estrogen receptor in vitro and its tissue distribution in vivo. The Journal of Steroid Biochemistry and Molecular Biology. 42: 363-73. PMID 1606047 DOI: 10.1016/0960-0760(92)90141-5 |
0.476 |
|
| 1992 |
Liu A, Carlson KE, Katzenellenbogen JA. Synthesis of high affinity fluorine-substituted ligands for the androgen receptor. Potential agents for imaging prostatic cancer by positron emission tomography. Journal of Medicinal Chemistry. 35: 2113-29. PMID 1597861 DOI: 10.1021/Jm00089A024 |
0.465 |
|
| 1992 |
Pinney KG, Carlson KE, Katzenellenbogen JA. Nonsteroidal estrogens bearing acyl azide functions: potential electrophilic and photoaffinity labeling agents for the estrogen receptor. Steroids. 57: 222-32. PMID 1488784 DOI: 10.1016/0039-128X(92)90106-J |
0.751 |
|
| 1992 |
Rai R, Katzenellenbogen JA. Effect of conformational mobility and hydrogen-bonding interactions on the selectivity of some guanidinoaryl-substituted mechanism-based inhibitors of trypsin-like serine proteases Journal of Medicinal Chemistry. 35: 4297-4305. PMID 1447734 DOI: 10.1021/Jm00101A006 |
0.301 |
|
| 1992 |
Hwang KJ, Carlson KE, Anstead GM, Katzenellenbogen JA. Donor-acceptor tetrahydrochrysenes, inherently fluorescent, high-affinity ligands for the estrogen receptor: Binding and fluorescence characteristics and fluorometric assay of receptor Biochemistry. 31: 11536-11545. PMID 1445887 DOI: 10.1021/Bi00161A035 |
0.473 |
|
| 1992 |
Hwang KJ, O'Neil JP, Katzenellenbogen JA. 5,6,11,12-Tetrahydrochrysenes: synthesis of rigid stilbene systems designed to be fluorescent ligands for the estrogen receptor The Journal of Organic Chemistry. 57: 1262-1271. DOI: 10.1021/JO00030A039 |
0.34 |
|
| 1992 |
VanBrocklin HF, Pomper MG, Carlson KE, Welch MJ, Katzenellenbogen JA. Erratum: Preparation and evaluation of 17-ethynyl-substituted 16α-[18F]fluoroestradiols: selective receptor-based PET imaging agents (Nuclear Medicine and Biology - International Journal of Radiation Applications and instrumentation Part B (Vol.nr. 19) (363-374)) Nuclear Medicine and Biology. 19. DOI: 10.1016/0883-2897(92)90165-U |
0.345 |
|
| 1991 |
Pinney KG, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Efficient and selective photoaffinity labeling of the estrogen receptor using two nonsteroidal ligands that embody aryl azide or tetrafluoroaryl azide photoreactive functions. Biochemistry. 30: 2421-31. PMID 2001370 DOI: 10.1021/Bi00223A018 |
0.734 |
|
| 1991 |
DiZio JP, Fiaschi R, Davison A, Jones AG, Katzenellenbogen JA. Progestin-rhenium complexes: Metal-labeled steroids with high receptor binding affinity, potential receptor-directed agents for diagnostic imaging or therapy Bioconjugate Chemistry. 2: 353-366. PMID 1790176 DOI: 10.1021/Bc00011A011 |
0.424 |
|
| 1991 |
Pinney KG, Katzenellenbogen JA. Synthesis of a tetrafluoro-substituted aryl azide and its protio analog as photoaffinity labeling reagents for the estrogen receptor The Journal of Organic Chemistry. 56: 3125-3133. DOI: 10.1021/Jo00009A037 |
0.703 |
|
| 1991 |
Pinney KG, Katzenellenbogen JA. Synthesis of a tetrafluoro-substituted aryl azide and its protio analogue as photoaffinity labeling reagents for the estrogen receptor Journal of Organic Chemistry. 56: 3125-3133. |
0.684 |
|
| 1990 |
Pomper MG, Pinney KG, Carlson KE, van Brocklin H, Mathias CJ, Welch MJ, Katzenellenbogen JA. Target tissue uptake selectivity of three fluorine-substituted progestins: potential imaging agents for receptor-positive breast tumors. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 17: 309-19. PMID 2341287 DOI: 10.1016/0883-2897(90)90058-9 |
0.714 |
|
| 1990 |
Pinney KG, Carlson KE, Katzenellenbogen JA. [3H]DU41165: a high affinity ligand and novel photoaffinity labeling reagent for the progesterone receptor. Journal of Steroid Biochemistry. 35: 179-89. PMID 2308335 DOI: 10.1016/0022-4731(90)90272-T |
0.688 |
|
| 1990 |
Carlson KE, Katzenellenbogen JA. A comparative study of the selectivity and efficiency of target tissue uptake of five tritium-labeled androgens in the rat. Journal of Steroid Biochemistry. 36: 549-61. PMID 2214772 DOI: 10.1016/0022-4731(90)90172-O |
0.375 |
|
| 1990 |
Anstead GM, Peterson CS, Pinney KG, Wilson SR, Katzenellenbogen JA. Torsionally and hydrophobically modified 2,3-diarylindenes as estrogen receptor ligands. Journal of Medicinal Chemistry. 33: 2726-34. PMID 2213825 DOI: 10.1021/Jm00172A008 |
0.667 |
|
| 1990 |
Vanbrocklin HF, Brodack JW, Mathias CJ, Welch MJ, Katzenellenbogen JA, Keenan JF, Mizejewski GJ. Binding of 16α-[18F]fluoro-17β-estradiol to alphafetoprotein in Sprague-Dawley female rats affects blood levels Nuclear Medicine and Biology. 17: 769-773. PMID 1706690 DOI: 10.1016/0883-2897(90)90024-U |
0.335 |
|
| 1990 |
Pomper MG, VanBrocklin H, Thieme AM, Thomas RD, Kiesewetter DO, Carlson KE, Mathias CJ, Welch MJ, Katzenellenbogen JA. 11 beta-methoxy-, 11 beta-ethyl- and 17 alpha-ethynyl-substituted 16 alpha-fluoroestradiols: receptor-based imaging agents with enhanced uptake efficiency and selectivity. Journal of Medicinal Chemistry. 33: 3143-55. PMID 1701833 DOI: 10.1021/Jm00174A009 |
0.518 |
|
| 1989 |
Fevig TL, Mao MK, Katzenellenbogen JA. Estrogen receptor binding tolerance of 16 alpha-substituted estradiol derivatives. Steroids. 51: 471-97. PMID 3242172 DOI: 10.1016/0039-128X(88)90046-3 |
0.493 |
|
| 1989 |
Anstead GM, Wilson SR, Katzenellenbogen JA. 2-Arylindenes and 2-arylindenones: Molecular structures and considerations in the binding orientation of unsymmetrical nonsteroidal ligands to the estrogen receptor Journal of Medicinal Chemistry. 32: 2163-2171. PMID 2769689 DOI: 10.1021/Jm00129A024 |
0.493 |
|
| 1989 |
Anstead GM, Peterson CS, Katzenellenbogen JA. Hydroxylated 2,3-diarylindenes: Synthesis, estrogen receptor binding affinity, and binding orientation considerations Journal of Steroid Biochemistry. 33: 877-887. PMID 2601332 DOI: 10.1016/0022-4731(89)90235-5 |
0.477 |
|
| 1989 |
Carlson KE, Coppey M, Magdelenat H, Katzenellenbogen JA. Receptor binding of NBD-labeled fluorescent estrogens and progestins in whole cells and cell-free preparations. Journal of Steroid Biochemistry. 32: 345-55. PMID 2539536 DOI: 10.1016/0022-4731(89)90206-9 |
0.509 |
|
| 1989 |
Anstead GM, Ensign JL, Peterson CS, Katzenellenbogen JA. 2-Arylindenes and 2-arylindenones. Synthesis of probes to study the binding orientation of unsymmetrical nonsteroidal ligands to the estrogen receptor The Journal of Organic Chemistry. 54: 1485-1491. DOI: 10.1021/JO00268A003 |
0.429 |
|
| 1989 |
ANSTEAD GM, ENSIGN JL, PETERSON CS, KATZENELLENBOGEN JA. ChemInform Abstract: 2-Arylindenes and 2-Arylindenones: Synthesis of Probes to Study the Binding Orientation of Unsymmetrical Nonsteroidal Ligands to the Estrogen Receptor. Cheminform. 20. DOI: 10.1002/CHIN.198942113 |
0.429 |
|
| 1988 |
Bindal RD, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Lipophilic impurities, not phenolsulfonphthalein, account for the estrogenic activity in commercial preparations of phenol red Journal of Steroid Biochemistry. 31: 287-293. PMID 3419159 DOI: 10.1016/0022-4731(88)90352-4 |
0.467 |
|
| 1988 |
Anstead GM, Katzenellenbogen JA. Optimizing of 2,3-diarylindenes as fluorescent estrogens: Variation of the acceptor group, ortho substitution of the 2-ring, and C-1 methylation Journal of Medicinal Chemistry. 31: 1754-1761. PMID 3411601 DOI: 10.1021/Jm00117A014 |
0.434 |
|
| 1988 |
Anstead GM, Altenbach RJ, Wilson SR, Katzenellenbogen JA. 2,3-diarylindenes and 2,3-diarylindenones: Synthesis, molecular structure, photochemistry, estrogen receptor binding affinity, and comparisons with related triarylethylenes Journal of Medicinal Chemistry. 31: 1316-1326. PMID 3385728 DOI: 10.1021/JM00402A011 |
0.302 |
|
| 1988 |
Brandes SJ, Katzenellenbogen JA. Fundamental considerations in the design of fluorine-18 labeled progestins and androgens as imaging agents for receptor-positive tumors of the breast and prostate. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 15: 53-67. PMID 3280523 DOI: 10.1016/0883-2897(88)90162-6 |
0.331 |
|
| 1988 |
Mintun MA, Welch MJ, Siegel BA, Mathias CJ, Brodack JW, McGuire AH, Katzenellenbogen JA. Breast cancer: PET imaging of estrogen receptors. Radiology. 169: 45-8. PMID 3262228 DOI: 10.1148/Radiology.169.1.3262228 |
0.38 |
|
| 1988 |
Pomper MG, Katzenellenbogen JA, Welch MJ, Brodack JW, Mathias CJ. 21-[18F]fluoro-16α-ethyl-19-norprogesterone: Synthesis and target tissue selective uptake of a progestin receptor based radiotracer for positron emission tomography Journal of Medicinal Chemistry. 31: 1360-1363. PMID 3260285 DOI: 10.1021/Jm00402A019 |
0.566 |
|
| 1988 |
Welch MJ, Katzenellenbogen JA, Mathias CJ, Brodack JW, Carlson KE, Chi DY, Dence CS, Kilbourn MR, Perlmutter JS, Raichle ME. N-(3-[18F]fluoropropyl)-spiperone: the preferred 18F labeled spiperone analog for positron emission tomographic studies of the dopamine receptor. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 15: 83-97. PMID 3258305 DOI: 10.1016/0883-2897(88)90164-X |
0.663 |
|
| 1988 |
Carlson KE, Brandes SJ, Pomper MG, Katzenellenbogen JA. Uptake of three [3H]progestins by target tissues in vivo; Implications for the design of diagnostic imaging agents Nuclear Medicine and Biology. 15: 403-408. PMID 3255736 DOI: 10.1016/0883-2897(88)90010-4 |
0.553 |
|
| 1988 |
Bindal RD, Katzenellenbogen JA. Bis(4-hydroxyphenyl)[2-(phenoxysulfonyl)phenyl]methane: isolation and structure elucidation of a novel estrogen from commercial preparations of phenol red (phenolsulfonphthalein) Journal of Medicinal Chemistry. 31: 1978-83. PMID 3172132 DOI: 10.1021/Jm00118A020 |
0.478 |
|
| 1988 |
Carlson KE, Brandes SJ, Pomper MG, Katzenellenbogen JA. Uptake of three [3H]progestins by target tissues in vivo: Implications for the design of diagnostic imaging agents International Journal of Radiation Applications and Instrumentation.. 15: 403-408. DOI: 10.1016/0883-2897(88)90010-4 |
0.489 |
|
| 1988 |
ANSTEAD GM, ALTENBACH RJ, WILSON SR, KATZENELLENBOGEN JA. ChemInform Abstract: 2,3-Diarylindenes and 2,3-Diarylindenones: Synthesis, Molecular Structure, Photochemistry, Estrogen Receptor Binding Affinity, and Comparisons with Related Triarylethylenes. Cheminform. 19. DOI: 10.1002/CHIN.198849135 |
0.386 |
|
| 1987 |
Katzenellenbogen JA, Carlson KE, Bindal RD, Neeley RL, Martin PM, Magdelenat HP. Fluorescence-based assay of estrogen receptor using 12-oxo-9(11)-dehydroestradiol-17 beta. Analytical Biochemistry. 159: 336-48. PMID 3826620 DOI: 10.1016/0003-2697(86)90351-9 |
0.441 |
|
| 1987 |
Welch MJ, Chi DY, Mathias CJ, Kilbourn MR, Brodack JW, Katzenellenbogen JA. Biodistribution of N-alkyl and N-fluoroalkyl derivatives of spiroperidol; radiopharmaceuticals for PET studies of dopamine receptors. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 13: 523-6. PMID 3818316 DOI: 10.1016/0883-2897(86)90132-7 |
0.653 |
|
| 1987 |
Boulanger WA, Katzenellenbogen JA. Structure-activity study of 6-substituted 2-pyranones as inactivators of alpha-chymotrypsin. Journal of Medicinal Chemistry. 29: 1159-63. PMID 3806568 DOI: 10.1021/Jm00157A007 |
0.375 |
|
| 1987 |
Bindal RD, Carlson KE, Reiner GC, Katzenellenbogen JA. 11 beta-chloromethyl-[3H]estradiol-17 beta: a very high affinity, reversible ligand for the estrogen receptor. Journal of Steroid Biochemistry. 28: 361-70. PMID 3669657 DOI: 10.1016/0022-4731(87)91052-1 |
0.439 |
|
| 1987 |
Simpson DM, Elliston JF, Katzenellenbogen JA. Desmethylnafoxidine aziridine: an electrophilic affinity label for the estrogen receptor with high efficiency and selectivity. Journal of Steroid Biochemistry. 28: 233-45. PMID 3657146 DOI: 10.1016/0022-4731(87)91014-4 |
0.528 |
|
| 1987 |
Elliston JF, Zablocki JA, Katzenellenbogen BS, Katzenellenbogen JA. Ketononestrol aziridine, an agonistic estrogen receptor affinity label: Study of its bioactivity and estrogen receptor covalent labeling Endocrinology. 121: 667-676. PMID 3595536 DOI: 10.1210/Endo-121-2-667 |
0.495 |
|
| 1987 |
Mathias CJ, Welch MJ, Katzenellenbogen JA, Brodack JW, Kilbourn MR, Carlson KE, Kiesewetter DO. Characterization of the uptake of 16α-([18F]fluoro)-17β-estradiol in DMBA-induced mammary tumors Nuclear Medicine and Biology. 14: 15-25. PMID 3108199 DOI: 10.1016/0883-2897(87)90156-5 |
0.551 |
|
| 1987 |
Zablocki JA, Katzenellenbogen JA, Carlson KE, Norman MJ, Katzenellenbogen BS. Estrogenic affinity labels: Synthesis, irreversible receptor binding, and bioactivity of aziridine-substituted hexestrol derivatives Journal of Medicinal Chemistry. 30: 829-838. PMID 3033242 DOI: 10.1021/Jm00388A015 |
0.457 |
|
| 1987 |
Chi DY, Kilbourn MR, Katzenellenbogen JA, Brodack JW, Welch MJ. Synthesis of no-carrier-added N-([18F]fluoroalkyl)spiperone derivatives. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 37: 1173-80. PMID 3028983 DOI: 10.1016/0883-2889(86)90002-X |
0.635 |
|
| 1987 |
Fevig TL, Lloyd JE, Zablocki JA, Katzenellenbogen JA. Preparation, receptor binding, and fluorescence properties of hexestrol-fluorophore conjugates: evaluation of site of attachment, fluorophore structure, and fluorophore-ligand spacing. Journal of Medicinal Chemistry. 30: 156-65. PMID 3027331 DOI: 10.1021/Jm00384A026 |
0.5 |
|
| 1987 |
Chi DY, Kilbourn MR, Katzenellenbogen JA, Welch MJ. A rapid and efficient method for the fluoroalkylation of amines and amides. Development of a method suitable for incorporation of the short-lived positron emitting radionuclide fluorine-18 The Journal of Organic Chemistry. 52: 658-664. DOI: 10.1021/JO00380A030 |
0.459 |
|
| 1987 |
Dae YC, Kilbourn MR, Katzenellenbogen JA, Welch MJ. A rapid and efficient method for the fluoroalkylation of amines and amides. Development of a method suitable for incorporation of the short-lived positron emitting radionuclide fluorine-18 Journal of Organic Chemistry. 52: 658-664. DOI: 10.1021/Jo00380A030 |
0.479 |
|
| 1987 |
ZABLOCKI JA, KATZENELLENBOGEN JA, CARLSON KE, NORMAN MJ, KATZENELLENBOGEN BS. ChemInform Abstract: Estrogenic Affinity Labels: Synthesis, Irreversible Receptor Binding, and Bioactivity of Aziridine-Substituted Hexestrol Derivatives. Cheminform. 18. DOI: 10.1002/CHIN.198746375 |
0.407 |
|
| 1987 |
CHI DY, KILBOURN MR, KATZENELLENBOGEN JA, WELCH MJ. ChemInform Abstract: A Rapid and Efficient Method for the Fluoroalkylation of Amines and Amides. Development of a Method Suitable for Incorporation of the Short-Lived Positron Emitting Radionuclide Fluorine-18. Cheminform. 18. DOI: 10.1002/CHIN.198733120 |
0.464 |
|
| 1987 |
FEVIG TL, LLOYD JE, ZABLOCKI JA, KATZENELLENBOGEN JA. ChemInform Abstract: Preparation, Receptor Binding, and Fluorescence Properties of Hexestrol-Fluorophore Conjugates: Evaluation of Site of Attachment, Fluorophore Structure, and Fluorophore-Ligand Spacing. Cheminform. 18. DOI: 10.1002/CHIN.198724210 |
0.304 |
|
| 1986 |
Bindal RD, Katzenellenbogen JA. 1,2-Diaryl-3,4-dihydronaphthalenes: photofluorogenic ligands for the estrogen receptor. Journal of Steroid Biochemistry. 23: 929-37. PMID 4094420 DOI: 10.1016/0022-4731(85)90049-4 |
0.455 |
|
| 1986 |
Daniels SB, Katzenellenbogen JA. Halo enol lactones: studies on the mechanism of inactivation of alpha-chymotrypsin. Biochemistry. 25: 1436-44. PMID 3964685 DOI: 10.1021/Bi00354A037 |
0.307 |
|
| 1986 |
Wei LL, Katzenellenbogen BS, Robertson DW, Simpson DM, Katzenellenbogen JA. Nitrosourea and nitrosocarbamate derivatives of the antiestrogen tamoxifen as potential estrogen receptor-mediated cytotoxic agents in human breast cancer cells Breast Cancer Research and Treatment. 7: 77-90. PMID 3719114 DOI: 10.1007/Bf01806792 |
0.487 |
|
| 1986 |
Bindal RD, Katzenellenbogen JA. 1,2-bis(4-Hydroxyphenyl)-3,4-dihydro-6-hydroxynaphthalene, a photofluorogenic ligand for the estrogen receptor. Photochemistry and Photobiology. 43: 121-6. PMID 3703953 DOI: 10.1111/J.1751-1097.1986.Tb09502.X |
0.439 |
|
| 1986 |
Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture Proceedings of the National Academy of Sciences of the United States of America. 83: 2496-2500. PMID 3458212 DOI: 10.1073/Pnas.83.8.2496 |
0.401 |
|
| 1986 |
Salituro FG, Carlson KE, Elliston JF, Katzenellenbogen BS, Katzenellenbogen JA. [125I]Iododesethyl tamoxifen aziridine: Synthesis and covalent labeling of the estrogen receptor with an iodine-labeled affinity label Steroids. 48: 287-313. PMID 3445283 DOI: 10.1016/0039-128X(86)90017-6 |
0.517 |
|
| 1986 |
Brodack JW, Kilbourn MR, Welch MJ, Katzenellenbogen JA. NCA 16 alpha-[18F]fluoroestradiol-17 beta: the effect of reaction vessel on fluorine-18 resolubilization, product yield, and effective specific activity. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 37: 217-21. PMID 3019933 DOI: 10.1016/0883-2889(86)90174-7 |
0.472 |
|
| 1986 |
Dae YC, Kiesewetter DO, Katzenellenbogen JA, Kilbourn MR, Welch MJ. Halofluorination of olefins: elucidation of reaction characteristics and applications in labeling with the positron-emitting radionuclide fluorine-18 Journal of Fluorine Chemistry. 31: 99-113. DOI: 10.1016/S0022-1139(00)85091-5 |
0.497 |
|
| 1986 |
CHI DY, KIESEWETTER DO, KATZENELLENBOGEN JA, KILBOURN MR, WELCH MJ. ChemInform Abstract: Halofluorination of Olefins: Elucidation of Reaction Characteristics and Applications in Labeling with the Positron-Emitting Radionuclide Fluorine-18. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198629107 |
0.466 |
|
| 1985 |
Katzenellenbogen JA, Carlson KE, Katzenellenbogen BS. Facile geometric isomerization of phenolic non-steroidal estrogens and antiestrogens: Limitations to the interpretation of experiments characterizing the activity of individual isomers Journal of Steroid Biochemistry. 22: 589-596. PMID 4010284 DOI: 10.1016/0022-4731(85)90210-9 |
0.473 |
|
| 1984 |
Monsma FJ, Katzenellenbogen BS, Miller MA, Ziegler YS, Katzenellenbogen JA. Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching antiestrogen. Endocrinology. 115: 143-53. PMID 6734512 DOI: 10.1210/Endo-115-1-143 |
0.47 |
|
| 1984 |
Landvatter SW, Kiesewetter DO, Kilbourn MR, Katzenellenbogen JA, Welch MJ. (2R*, 3S*)-1-[18F]fluoro-2,3-bis(4-hydroxyphenyl)pentane [( 18F]fluoronor-hexestrol), a positron-emitting estrogen that shows highly-selective, receptor-mediated uptake by target tissues in vivo. Life Sciences. 33: 1933-8. PMID 6316052 DOI: 10.1016/0024-3205(83)90678-1 |
0.625 |
|
| 1984 |
Kiesewetter DO, Katzenellenbogen JA, Kilbourn MR, Welch MJ. Synthesis of 16-fluoroestrogens by unusually facile fluoride ion displacement reactions: prospects for the preparation of fluorine-18 labeled estrogens The Journal of Organic Chemistry. 49: 4900-4905. DOI: 10.1021/Jo00199A031 |
0.54 |
|
| 1984 |
Katzenellenbogen JA, Katzenellenbogen BS. Affinity labeling of receptors for steroid and thyroid hormones Vitamins and Hormones. 213-274. DOI: 10.1016/S0083-6729(08)60091-6 |
0.45 |
|
| 1984 |
Katzenellenbogen JA. Radiolabeled antiestrogens: Synthesis, metabolism and receptor interaction studies Journal of Steroid Biochemistry. 20: 1628. DOI: 10.1016/0022-4731(84)90939-7 |
0.384 |
|
| 1983 |
Chakravarty PK, Carl PL, Weber MJ, Katzenellenbogen JA. Plasmin-activated prodrugs for cancer chemotherapy. II. Synthesis and biological activity of peptidyl derivatives of doxorubicin Journal of Medicinal Chemistry. 26: 638-644. PMID 6302253 DOI: 10.1002/Chin.198338340 |
0.302 |
|
| 1983 |
Landvatter SW, Katzenellenbogen JA, McElvany KD, Welch MJ. (2R*,3S*)-1-[125I]Iodo-2,3-bis(4-hydroxyphenyl)pentane ([125I]iodonorhexestrol) and (2R*,3S*)-1-[77Br]Bromo-2,3-bis(4-hydroxyphenyl)pentane ([77Br]bromonorhexestrol), two gamma-emitting estrogens that show receptor-mediated uptake by target tissues in vivo. Journal of Medicinal Chemistry. 25: 1307-12. PMID 6292424 DOI: 10.1021/Jm00353A007 |
0.388 |
|
| 1983 |
Landvatter SW, Katzenellenbogen JA. Nonsteroidal estrogens: synthesis and estrogen receptor binding affinity of derivatives of (3R*,4S*)-3,4-bis(4-hydroxyphenyl)hexane (hexestrol) and (2R*,3S*)-2,3-bis(4-hydroxyphenyl)pentane (norhexestrol) functionalized on the side chain. Journal of Medicinal Chemistry. 25: 1300-7. PMID 6292423 DOI: 10.1021/Jm00353A006 |
0.477 |
|
| 1983 |
McElvany KD, Carlson KE, Katzenellenbogen JA, Welch MJ. Factors affecting the target site uptake selectivity of estrogen radiopharmaceuticals: serum binding and endogenous estrogens. Journal of Steroid Biochemistry. 18: 635-41. PMID 6191127 DOI: 10.1016/0022-4731(83)90240-6 |
0.467 |
|
| 1983 |
LANDVATTER SW, KATZENELLENBOGEN JA, MCELVANY KD, WELCH MJ. ChemInform Abstract: (2R*,3S*)-1-(125I)IODO-2,3-BIS(4-HYDROXYPHENYL)PENTANE ((125I)IODONORHEXESTROL), AND (2R*,3S*)-1-(77BR)BROMO-2,3-BIS(4-HYDROXYPHENYL)PENTANE ((77BR)BROMONORHEXESTROL), TWO Γ-EMITTING ESTROGENS THAT SHOW RECEPTOR-MEDIATED UPTAKE BY TAR Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198317174 |
0.34 |
|
| 1982 |
Robertson DW, Katzenellenbogen JA, Long DJ, Rorke EA, Katzenellenbogen BS. Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen. Journal of Steroid Biochemistry. 16: 1-13. PMID 7062732 DOI: 10.1016/0022-4731(82)90137-6 |
0.327 |
|
| 1982 |
Robertson DW, Katzenellenbogen JA, Hayes JR, Katzenellenbogen BS. Antiestrogen basicity-activity relationships: A comparison of the estrogen receptor binding and antiuterotrophic potencies of several analogues of (Z)-1,2-diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1-butene (tamoxifen, Nolvadex) having altered basicity Journal of Medicinal Chemistry. 25: 167-171. PMID 7057423 DOI: 10.1021/Jm00344A015 |
0.453 |
|
| 1982 |
Robertson DW, Katzenellenbogen JA. Synthesis of the (E) and (Z) isomers of the antiestrogen tamoxifen and its metabolite, hydroxytamoxifen, in tritium-labeled form The Journal of Organic Chemistry. 47: 2387-2393. DOI: 10.1021/Jo00133A030 |
0.32 |
|
| 1982 |
Katzenellenbogen J, Carlson K, Robertson D, Heiman D. 100. Highly selective affinity labeling of the estrogen receptor with tamoxifen aziridine Journal of Steroid Biochemistry. 17: xxxiv. DOI: 10.1016/0022-4731(82)90314-4 |
0.49 |
|
| 1982 |
Katzenellenbogen JA, Katzenellenbogen BS. Considerations in the design and evaluation of cytotoxic estrogens Breast Cancer Research and Treatment. 2: 347-353. DOI: 10.1007/Bf01805876 |
0.49 |
|
| 1982 |
Krafft GA, Reich MF, Katzenellenbogen JA. Synthesis of 14C-labeled 10,11-epoxyfarnesyl diazoacetate, a potential photoaffinity labeling reagent for insect juvenile hormone binding proteins Journal of Labelled Compounds and Radiopharmaceuticals. 19: 591-596. DOI: 10.1002/Jlcr.2580190413 |
0.35 |
|
| 1982 |
ROBERTSON DW, KATZENELLENBOGEN JA, HAYES JR, KATZENELLENBOGEN BS. ChemInform Abstract: ANTIESTROGEN BASICITY-ACTIVITY RELATIONSHIPS: A COMPARISON OF THE ESTROGEN RECEPTOR BINDING AND ANTIUTEROTROPHIC POTENCIES OF SEVERAL ANALOGS OF (Z)-1,2-DIPHENYL-1-(4-(2-(DIMETHYLAMINO)ETHOXY)PHENYL)-1-BUTENE (TAMOXIFEN, NOLVADEX) HAV Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198226152 |
0.516 |
|
| 1981 |
Robertson DW, Wei LL, Hayes JR, Carlson KE, Katzenellenbogen JA, Katzenellenbogen BS. Tamoxifen aziridines: effective inactivators of the estrogen receptor. Endocrinology. 109: 1298-300. PMID 7285873 DOI: 10.1210/Endo-109-4-1298 |
0.518 |
|
| 1981 |
de Boer W, Notides AC, Katzenellenbogen BS, Hayes JR, Katzenellenbogen JA. The capacity of the antiestrogen CI-628 to activate the estrogen receptor in vitro Endocrinology. 108: 206-212. PMID 7007019 DOI: 10.1210/Endo-108-1-206 |
0.326 |
|
| 1981 |
Hayes JR, Rorke EA, Robertson DW, Katzenellenbogen BS, Katzenellenbogen JA. Biological potency and uterine estrogen receptor interaction of the metabolites of the antiestrogens CI628 and U23,469 Endocrinology. 108: 164-172. PMID 7007017 DOI: 10.1210/Endo-108-1-164 |
0.447 |
|
| 1981 |
Katzenellenbogen JA, McGorrin RJ, Tatee T, Kempton RJ, Carlson KE, Kinder DH. Chemically reactive estrogens: synthesis and estrogen receptor interactions of hexestrol ether derivatives and 4-substituted deoxyhexestrol derivatives bearing alkylating functions. Journal of Medicinal Chemistry. 24: 435-50. PMID 6267281 DOI: 10.1002/Chin.198134187 |
0.839 |
|
| 1981 |
Ng JS, Katzenellenbogen JA, Kilbourn MR. Aromatic fluorinations suitable for fluorine-18 labeling of estrogens The Journal of Organic Chemistry. 46: 2520-2528. DOI: 10.1021/Jo00325A017 |
0.535 |
|
| 1981 |
Heiman D, Senderoff S, Katzenellenbogen J, Neeley R. Additions and Corrections - Estrogen Receptor Based Imaging Agents. 1. Synthesis and Receptor Binding Affinity of Some Aromatic and D-Ring Halogenated Estrogens. Journal of Medicinal Chemistry. 24: 1540-1540. DOI: 10.1021/Jm00144A601 |
0.494 |
|
| 1981 |
Katzenellenbogen JA, Tatee T, Robertson DW. Preparation of tritium-labeled 4-hydroxy-α-[p-(2-(N-pyrrolidinyl) ethoxy) phenyl]-α′-nitrostilbene (CN-928), a biologically-important metabolite of the antiestrogen CI-628 Journal of Labelled Compounds and Radiopharmaceuticals. 18: 865-879. DOI: 10.1002/Jlcr.2580180612 |
0.313 |
|
| 1981 |
Goswami R, Kilbourn MR, Katzenellenbogen JA. 1-dehydrohexestrol. Synthesis of a precursor for the preparation of tritium-labeled hexestrol derivatives and its use in a new, convenient synthesis of tritium-labeled o-azido-hexestrol Journal of Labelled Compounds and Radiopharmaceuticals. 18: 407-418. DOI: 10.1002/Jlcr.2580180315 |
0.532 |
|
| 1981 |
KATZENELLENBOGEN JA, MCGORRIN RJ, TATEE T, KEMPTON RJ, CARLSON KE, KINDER DH. ChemInform Abstract: CHEMICALLY REACTIVE ESTROGENS: SYNTHESIS AND ESTROGEN RECEPTOR INTERACTIONS OF HEXESTROL ETHER DERIVATIVES AND 4-SUBSTITUTED DEOXYHEXESTROL DERIVATIVE BEARING ALKYLATING FUNCTIONS Chemischer Informationsdienst. 12. DOI: 10.1002/CHIN.198134187 |
0.351 |
|
| 1981 |
HEIMAN DF, SENDEROFF SG, KATZENELLENBOGEN JA, NEELEY RJ. ChemInform Abstract: ESTROGEN RECEPTOR-BASED IMAGING AGENTS. 1. SYNTHESIS AND RECEPTOR BINDING AFFINITY OF SOME AROMATIC AND D-RING HALOGENATED ESTROGENS Chemischer Informationsdienst. 12. DOI: 10.1002/CHIN.198109355 |
0.395 |
|
| 1981 |
GOSWAMY R, HARSY SG, HEIMAN DF, KATZENELLENBOGEN JA. ChemInform Abstract: ESTROGEN RECEPTOR BASED IMAGING AGENTS. 2. SYNTHESIS AND RECEPTOR BINDING AFFINITY OF SIDE-CHAIN HALOGENATED HEXESTROL DERIVATIVES Chemischer Informationsdienst. 12. DOI: 10.1002/CHIN.198109207 |
0.389 |
|
| 1980 |
Heiman DF, Senderoff SG, Katzenellenbogen JA, Neeley RJ. Estrogen receptor based imaging agents. 1. Synthesis and receptor binding affinity of some aromatic and D-ring halogenated estrogens. Journal of Medicinal Chemistry. 23: 994-1002. PMID 7411555 DOI: 10.1002/Chin.198109355 |
0.52 |
|
| 1980 |
Payne DW, Katzenellenbogen JA. Differential effects of estrogens in tissues: a comparison of estrogen receptor in rabbit uterus and vagina. Endocrinology. 106: 1345-52. PMID 7363855 DOI: 10.1210/Endo-106-5-1345 |
0.449 |
|
| 1980 |
Katzenellenbogen JA, Kilbourn MR, Carlson KE. Photosensitive steroids as probes of estrogen receptor sites. Annals of the New York Academy of Sciences. 346: 18-30. PMID 6930181 DOI: 10.1111/J.1749-6632.1980.Tb22088.X |
0.628 |
|
| 1980 |
Goswami R, Harsy SG, Heiman DF, Katzenellenbogen JA. Estrogen receptor based imaging agents. 2. Synthesis and receptor binding affinity of side-chain halogenated hexestrol derivatives. Journal of Medicinal Chemistry. 23: 1002-8. PMID 6251218 DOI: 10.1002/Chin.198109207 |
0.524 |
|
| 1980 |
Katzenellenbogen BS, Bhakoo HS, Ferguson ER, Lan NC, Tatee T, Tsai TS, Katzenellenbogen JA. Estrogen and antiestrogen action in reproductive tissues and tumors. Recent Progress in Hormone Research. 35: 259-300. PMID 229525 DOI: 10.1016/B978-0-12-571135-7.50010-2 |
0.461 |
|
| 1979 |
Tatee T, Carlson KE, Katzenellenbogen JA, Robertson DW, Katzenellenbogen BS. Antiestrogens and antiestrogen metabolites: Preparation of tritium-labeled (±)-cis-3-[p-(1,2,3,4-tetrahydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy]- 1,2-propanediol (U-23469) and characterization and synthesis of a biologically important metabolite Journal of Medicinal Chemistry. 22: 1509-1517. PMID 536996 DOI: 10.1021/Jm00198A015 |
0.374 |
|
| 1979 |
Katzenellenbogen BS, Tsai TS, Tatee T, Katzenellenbogen JA. Estrogen and antiestrogen action: studies in reproductive target tissues and tumors Advances in Experimental Medicine and Biology. 117: 111-132. PMID 474274 DOI: 10.1007/978-1-4757-6589-2_6 |
0.464 |
|
| 1979 |
Katzenellenbogen BS, Katzenellenbogen JA, Mordecai D. Zearalenones: Characterization of the estrogenic potencies and receptor interactions of a series of fungal β-resorcylic acid lactones Endocrinology. 105: 33-40. PMID 446414 DOI: 10.1210/Endo-105-1-33 |
0.453 |
|
| 1979 |
Payne DW, Katzenellenbogen JA. Binding specificity of rat alpha-fetoprotein for a series of estrogen derivatives: studies using equilibrium and nonequilibrium binding techniques. Endocrinology. 105: 745-53. PMID 89027 DOI: 10.1210/Endo-105-3-743 |
0.474 |
|
| 1978 |
Katzenellenbogen BS, Iwamoto HS, Heiman DF, Lan NC, Katzenellenbogen JA. Stilbestrols and stilbestrol derivatives: Estrogenic potency and temporal relationships between estrogen receptor binding and uterine growth Molecular and Cellular Endocrinology. 10: 103-113. PMID 564791 DOI: 10.1016/0303-7207(78)90063-1 |
0.434 |
|
| 1977 |
Carlson KE, Sun LH, Katzenellenbogen JA. Characterization of trypsin-treated forms of the estrogen receptor from rat and lamb uterus. Biochemistry. 16: 4288-96. PMID 901772 DOI: 10.1021/Bi00638A025 |
0.405 |
|
| 1977 |
Katzenellenbogen JA, Carlson KE, Johnson HJ, Myers HN. Estrogen photoaffinity labels. 2. Reversible binding and covalent attachment of photosensitive hexestrol derivatives to the uterine estrogen receptor Biochemistry. 16: 1970-1976. PMID 870034 DOI: 10.1021/Bi00628A034 |
0.443 |
|
| 1977 |
Katzenellenbogen JA, Myers HN, Johnson HJ, kempton RJ, Carlson KE. Estrogen photoaffinity labels. 1. Chemical and radiochemical synthesis of hexestrol diazoketone and azide derivatives; photochemical studies in solution. Biochemistry. 16: 1964-70. PMID 870033 DOI: 10.1021/Bi00628A033 |
0.77 |
|
| 1975 |
Katzenellenbogen JA, Hsiung HM. Iodohexestrols. I. Synthesis and photoreaotivity of iodinated hexestrol derivatives Biochemistry. 14: 1736-1741. PMID 1125197 DOI: 10.1021/Bi00679A028 |
0.392 |
|
| 1975 |
Katzenellenbogen JA, Ruh TS, Carlson KE, Iwamoto HS, Gorski J. Ultraviolet photosensitivity of the estrogen binding protein from rat uterus. Wavelength and ligand dependence. Photocovalent attachment of estrogens to proteins. Biochemistry. 14: 2310-6. PMID 166653 DOI: 10.1021/Bi00682A006 |
0.401 |
|
| 1975 |
Katzenellenbogen JA, Hsiung HM, Carlson KE, McGuire WL, Kraay RJ, Katzenellenbogen BS. Iodohexestrols. II. Characterization of the binding and estrogenic activity of iodinated hexestrol derivatives, in vitro and in vivo. Biochemistry. 14: 1742-50. PMID 164893 DOI: 10.1021/Bi00679A029 |
0.413 |
|
| 1974 |
Katzenellenbogen JA, Johnson HJ, Carlson KE, Myers HN. Photoreactivity of some light-sensitive estrogen derivatives. Use of an exchange assay to determine their photointeraction with the rat uterine estrogen binding protein Biochemistry. 13: 2986-2994. PMID 4407785 DOI: 10.1021/Bi00711A031 |
0.386 |
|
| 1974 |
Katzenellenbogen JA. Chapter 23. Affinity Labeling of Hormone Binding Sites Annual Reports in Medicinal Chemistry. 9: 222-233. DOI: 10.1016/S0065-7743(08)61445-1 |
0.379 |
|
| 1974 |
Katzenellenbogen J, Johnson H, Myers H, Carlson K. 123. An approach to affinity labelling of the estrogen binding protein from rat uterus Journal of Steroid Biochemistry. 5: 325. DOI: 10.1016/0022-4731(74)90268-4 |
0.358 |
|
| 1973 |
Katzenellenbogen JA, Myers HN, Johnson HJ. Reagents for photoaffinity labeling of estrogen binding proteins. Synthesis of some azide and diazo derivatives of estradiol, estrone, and hexestrol Journal of Organic Chemistry. 38: 3525-3533. PMID 4780823 DOI: 10.1002/Chin.197403401 |
0.412 |
|
| 1973 |
Katzenellenbogen JA, Johnson HJ, Carlson KE. Studies on the uterine, cytoplasmic estrogen binding protein. Thermal stability and ligand dissociation rate. An assay of empty and filled sites by exchange Biochemistry. 12: 4092-4099. PMID 4745661 DOI: 10.1021/Bi00745A011 |
0.392 |
|
| 1973 |
Katzenellenbogen JA, Johnson HJ, Myers HN. Photoaffinity labels for estrogen binding proteins of rat uterus Biochemistry. 12: 4085-4092. PMID 4745660 DOI: 10.1021/Bi00745A010 |
0.424 |
|
| 1973 |
Ruh TS, Katzenellenbogen BS, Katzenellenbogen JA, Gorski J. Estrone interaction with the rat uterus: in vitro response and nuclear uptake Endocrinology. 92: 125-134. PMID 4681918 DOI: 10.1210/Endo-92-1-125 |
0.384 |
|
| 1973 |
Katzenellenbogen BS, Katzenellenbogen JA. Antiestrogens: studies using an in vitro estrogen-responsive uterine system. Biochemical and Biophysical Research Communications. 50: 1152-9. PMID 4347895 DOI: 10.1016/0006-291X(73)91526-X |
0.358 |
|
| 1972 |
Katzenellenbogen JA, Corey EJ. Novel cyclization mediated by organocopper reagents The Journal of Organic Chemistry. 37: 1441-1442. DOI: 10.1021/Jo00974A034 |
0.446 |
|
| 1971 |
Corey EJ, Katzenellenbogen JA, Roman SA, Gilman NW. Stereospecific synthesis of a biologically active dehydro derivative of the C18-juvenile hormone of cecropia. New routes to a key C12-intermediate Tetrahedron Letters. 12: 1821-1824. DOI: 10.1016/S0040-4039(01)87471-2 |
0.34 |
|
| 1971 |
COREY EJ, KATZENELLENBOGEN JA, ROMAN SA, GILMAN NW. ChemInform Abstract: STEREOSPEZIFISCHE SYNTH. EINER BIOLOGISCH AKTIVEN DEHYDRO-VERBINDUNG DES C18-JUVENIL-HORMONS VON CECROPIA, NEUE WEGE ZU EINER C12-ZWISCHENSTUFE Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197137375 |
0.381 |
|
| 1971 |
COREY EJ, KIRST HA, KATZENELLENBOGEN JA. ChemInform Abstract: STEREOSPEZIFISCHE TOTALSYNTHESE VON ALPHA-SANTALOL Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197101271 |
0.377 |
|
| 1970 |
Corey EJ, Kirst HA, Katzenellenbogen JA. A Stereospecific Total Synthesis of α-Santalol Journal of the American Chemical Society. 92: 6314-6320. DOI: 10.1021/Ja00724A600 |
0.385 |
|
| 1969 |
Corey EJ, Achiwa K, Katzenellenbogen JA. Total synthesis of dl-sirenin Journal of the American Chemical Society. 91: 4318-4320. DOI: 10.1021/Ja01043A068 |
0.573 |
|
| 1969 |
Corey EJ, Katzenellenbogen JA. Stereospecific synthesis of trisubstituted and tetrasubstituted olefins. Conjugate addition of dialkylcopper-lithium reagents to .alpha.,.beta.-acetylenic esters Journal of the American Chemical Society. 91: 1851-1852. DOI: 10.1021/Ja01035A045 |
0.418 |
|
| 1968 |
Corey EJ, Katzenellenbogen JA, Gilman NW, Roman SA, Erickson BW. Stereospecific total synthesis of the dl-C18 Cecropia juvenile hormone Journal of the American Chemical Society. 90: 5618-5620. DOI: 10.1021/Ja01022A060 |
0.615 |
|
| 1967 |
Corey EJ, Katzenellenbogen JA, Posner GH. New stereospecific synthesis of trisubstituted olefins. Stereospecific synthesis of farnesol Journal of the American Chemical Society. 89: 4245-4247. DOI: 10.1021/Ja00992A065 |
0.548 |
|
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