Elaine W. Raines - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Cell Biology

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tang J, Frey JM, Wilson CL, Moncada-Pazos A, Levet C, Freeman M, Rosenfeld ME, Stanley ER, Raines EW, Bornfeldt KE. Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation. Molecular and Cellular Biology. PMID 29891514 DOI: 10.1128/Mcb.00103-18  0.377
2018 Tang J, Frey JM, Wilson CL, Moncada-Pazos A, Levet C, Freeman M, Stanley ER, Rosenfeld ME, Bornfeldt KE, Raines EW. Abstract 493: Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor-1 is Shed by a Disintegrin and Metalloprotease 17 and Contributes to Stimulating Macrophage Proliferation in Inflammation Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.493  0.369
2015 Feng Y, Tsai YH, Xiao W, Ralls MW, Stoeck A, Wilson CL, Raines EW, Teitelbaum DH, Dempsey PJ. Loss of ADAM17-mediated TNFα signaling in intestinal cells attenuates mucosal atrophy in a mouse model of parenteral nutrition. Molecular and Cellular Biology. PMID 26283731 DOI: 10.1128/Mcb.00143-15  0.344
2015 Razani B, Raines EW. Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype? Circulation Research. 116: 770-3. PMID 25722437 DOI: 10.1161/Circresaha.115.305922  0.309
2014 Palazuelos J, Crawford HC, Klingener M, Sun B, Karelis J, Raines EW, Aguirre A. TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11884-96. PMID 25186737 DOI: 10.1523/Jneurosci.1220-14.2014  0.314
2014 Nishizawa T, Kanter JE, Kramer F, Barnhart S, Shen X, Vivekanandan-Giri A, Wall VZ, Kowitz J, Devaraj S, O'Brien KD, Pennathur S, Tang J, Miyaoka RS, Raines EW, Bornfeldt KE. Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis. Cell Reports. 7: 356-65. PMID 24726364 DOI: 10.1016/J.Celrep.2014.03.028  0.34
2014 Tsubota Y, Frey JM, Raines EW. Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function. Journal of Leukocyte Biology. 95: 191-5. PMID 24006509 DOI: 10.1189/Jlb.0513272  0.317
2013 Cieslewicz M, Tang J, Yu JL, Cao H, Zavaljevski M, Motoyama K, Lieber A, Raines EW, Pun SH. Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival. Proceedings of the National Academy of Sciences of the United States of America. 110: 15919-24. PMID 24046373 DOI: 10.1073/Pnas.1312197110  0.319
2013 Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB. A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor. The Journal of Biological Chemistry. 288: 30742-51. PMID 24043629 DOI: 10.1074/Jbc.M113.492397  0.411
2013 Driscoll WS, Vaisar T, Tang J, Wilson CL, Raines EW. Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype. Circulation Research. 113: 52-61. PMID 23584255 DOI: 10.1161/Circresaha.112.300683  0.666
2013 Tsubota Y, Frey JM, Tai PW, Welikson RE, Raines EW. Monocyte ADAM17 promotes diapedesis during transendothelial migration: identification of steps and substrates targeted by metalloproteinases. Journal of Immunology (Baltimore, Md. : 1950). 190: 4236-44. PMID 23479224 DOI: 10.4049/Jimmunol.1300046  0.422
2013 Wilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW. Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mechanisms of Development. 130: 272-89. PMID 23354118 DOI: 10.1016/J.Mod.2013.01.001  0.339
2013 Lund SA, Wilson CL, Raines EW, Tang J, Giachelli CM, Scatena M. Osteopontin mediates macrophage chemotaxis via α4 and α9 integrins and survival via the α4 integrin. Journal of Cellular Biochemistry. 114: 1194-202. PMID 23192608 DOI: 10.1002/Jcb.24462  0.334
2013 Nguyen AT, Gomez D, Bell RD, Campbell JH, Clowes AW, Gabbiani G, Giachelli CM, Parmacek MS, Raines EW, Rusch NJ, Speer MY, Sturek M, Thyberg J, Towler DA, Weiser-Evans MC, et al. Smooth muscle cell plasticity: fact or fiction? Circulation Research. 112: 17-22. PMID 23093573 DOI: 10.1161/Circresaha.112.281048  0.404
2012 Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, ... ... Raines EW, et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 22: 304-17. PMID 22975374 DOI: 10.1016/J.Ccr.2012.07.024  0.305
2012 Gomez IG, Tang J, Wilson CL, Yan W, Heinecke JW, Harlan JM, Raines EW. Metalloproteinase-mediated Shedding of Integrin β2 promotes macrophage efflux from inflammatory sites. The Journal of Biological Chemistry. 287: 4581-9. PMID 22170060 DOI: 10.1074/Jbc.M111.321182  0.348
2011 Bowen-Pope DF, Raines EW. History of discovery: platelet-derived growth factor. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2397-401. PMID 22011752 DOI: 10.1161/Atvbaha.108.179556  0.362
2011 Tang J, Zarbock A, Gomez I, Wilson CL, Lefort CT, Stadtmann A, Bell B, Huang LC, Ley K, Raines EW. Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood. 118: 786-94. PMID 21628404 DOI: 10.1182/Blood-2010-11-321406  0.385
2011 de Claro RA, Zhu X, Tang J, Morgan-Stevenson V, Schwartz BR, Iwata A, Liles WC, Raines EW, Harlan JM. Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state. The American Journal of Pathology. 178: 2931-7. PMID 21550016 DOI: 10.1016/J.Ajpath.2011.02.011  0.336
2010 Raines EW, Bornfeldt KE. Integrin alpha(7)beta(1) COMPels smooth muscle cells to maintain their quiescence. Circulation Research. 106: 427-9. PMID 20167938 DOI: 10.1161/Circresaha.109.214072  0.4
2009 Vaisar T, Kassim SY, Gomez IG, Green PS, Hargarten S, Gough PJ, Parks WC, Wilson CL, Raines EW, Heinecke JW. MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages. Molecular & Cellular Proteomics : McP. 8: 1044-60. PMID 19116209 DOI: 10.1074/Mcp.M800449-Mcp200  0.317
2008 Liu L, Schwartz B, Tsubota Y, Raines E, Kiyokawa H, Yonekawa K, Harlan JM, Schnapp LM. Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 1808-17. PMID 18209078 DOI: 10.4049/Jimmunol.180.3.1808  0.393
2008 Schnapp LM, Liu L, Schwartz B, Chow Y, Tsubota Y, Raines EW, Harlan JM. Novel role of Cdk4 in leukocyte adhesion and trafficking Matrix Biology. 27: 32. DOI: 10.1016/J.Matbio.2008.09.308  0.349
2007 Wisse BE, Ogimoto K, Tang J, Harris MK, Raines EW, Schwartz MW. Evidence that lipopolysaccharide-induced anorexia depends upon central, rather than peripheral, inflammatory signals. Endocrinology. 148: 5230-7. PMID 17673516 DOI: 10.1210/En.2007-0394  0.318
2007 Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circulation Research. 100: 1589-96. PMID 17478729 DOI: 10.1161/Circresaha.106.142851  0.307
2007 Ferri N, Colombo G, Ferrandi C, Raines EW, Levkau B, Corsini A. Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1043-9. PMID 17303772 DOI: 10.1161/Atvbaha.107.139881  0.403
2007 Raines EW. Inflamed endothelium: an EPC adhesion kit Blood. 109: 4118-4118. DOI: 10.1182/Blood-2007-03-075762  0.354
2006 Garton KJ, Gough PJ, Raines EW. Emerging roles for ectodomain shedding in the regulation of inflammatory responses. Journal of Leukocyte Biology. 79: 1105-16. PMID 16565325 DOI: 10.1189/Jlb.0106038  0.756
2006 Raines EW. Antigen-independent targeting of long-lived CD4+ cytolytic T effector cells to lesions of atherosclerosis. Circulation Research. 98: 434-6. PMID 16514071 DOI: 10.1161/01.Res.0000214353.38360.A2  0.417
2006 Gough PJ, Gomez IG, Wille PT, Raines EW. Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice. The Journal of Clinical Investigation. 116: 59-69. PMID 16374516 DOI: 10.1172/Jci25074  0.361
2005 Tang J, Raines EW. Are suppressors of cytokine signaling proteins recently identified in atherosclerosis possible therapeutic targets? Trends in Cardiovascular Medicine. 15: 243-9. PMID 16226678 DOI: 10.1016/J.Tcm.2005.08.001  0.359
2005 Tang J, Kozaki K, Farr AG, Martin PJ, Lindahl P, Betsholtz C, Raines EW. The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice. The American Journal of Pathology. 167: 901-12. PMID 16127167 DOI: 10.1016/S0002-9440(10)62061-5  0.399
2005 Kim F, Tysseling KA, Rice J, Gallis B, Haji L, Giachelli CM, Raines EW, Corson MA, Schwartz MW. Activation of IKKbeta by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells. Journal of Molecular and Cellular Cardiology. 39: 327-34. PMID 15978611 DOI: 10.1016/J.Yjmcc.2005.05.009  0.322
2005 Raines EW, Ferri N. Thematic review series: The immune system and atherogenesis. Cytokines affecting endothelial and smooth muscle cells in vascular disease. Journal of Lipid Research. 46: 1081-92. PMID 15834121 DOI: 10.1194/Jlr.R500004-Jlr200  0.448
2005 Kim F, Tysseling KA, Rice J, Pham M, Haji L, Gallis BM, Baas AS, Paramsothy P, Giachelli CM, Corson MA, Raines EW. Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 989-94. PMID 15731493 DOI: 10.1161/01.Atv.0000160549.60980.A8  0.334
2005 Sanderson MP, Erickson SN, Gough PJ, Garton KJ, Wille PT, Raines EW, Dunbar AJ, Dempsey PJ. ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. The Journal of Biological Chemistry. 280: 1826-37. PMID 15507448 DOI: 10.1074/Jbc.M408804200  0.768
2004 Raines EW. PDGF and cardiovascular disease. Cytokine & Growth Factor Reviews. 15: 237-54. PMID 15207815 DOI: 10.1016/J.Cytogfr.2004.03.004  0.433
2004 Ferri N, Carragher NO, Raines EW. Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. The American Journal of Pathology. 164: 1575-85. PMID 15111304 DOI: 10.1016/S0002-9440(10)63716-9  0.429
2004 Raines EW, Garton KJ, Ferri N. Beyond the endothelium: NF-kappaB regulation of smooth muscle function. Circulation Research. 94: 706-8. PMID 15059939 DOI: 10.1161/01.Res.0000125646.08156.4D  0.765
2004 Raines EW. Nogo puts the brake on vascular lesions. Nature Medicine. 10: 348-9. PMID 15057228 DOI: 10.1038/Nm0404-348  0.35
2004 Shofuda T, Shofuda K, Ferri N, Kenagy RD, Raines EW, Clowes AW. Cleavage of focal adhesion kinase in vascular smooth muscle cells overexpressing membrane-type matrix metalloproteinases. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 839-44. PMID 15044209 DOI: 10.1161/01.Atv.0000126680.78500.4C  0.406
2004 Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. Journal of Immunology (Baltimore, Md. : 1950). 172: 3678-85. PMID 15004171 DOI: 10.4049/Jimmunol.172.6.3678  0.766
2003 Gough PJ, Raines EW. Advances in retroviral transduction of hematopoietic stem cells for the gene therapy of atherosclerosis. Current Opinion in Lipidology. 14: 491-7. PMID 14501588 DOI: 10.1097/00041433-200310000-00010  0.335
2003 Garton KJ, Gough PJ, Philalay J, Wille PT, Blobel CP, Whitehead RH, Dempsey PJ, Raines EW. Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). The Journal of Biological Chemistry. 278: 37459-64. PMID 12878595 DOI: 10.1074/Jbc.M305877200  0.773
2003 Ferri N, Garton KJ, Raines EW. An NF-kappaB-dependent transcriptional program is required for collagen remodeling by human smooth muscle cells. The Journal of Biological Chemistry. 278: 19757-64. PMID 12649281 DOI: 10.1074/Jbc.M212714200  0.754
2003 Levkau B, Kenagy RD, Karsan A, Weitkamp B, Clowes AW, Ross R, Raines EW. Activation of metalloproteinases and their association with integrins: an auxiliary apoptotic pathway in human endothelial cells. Cell Death and Differentiation. 9: 1360-7. PMID 12478473 DOI: 10.1038/Sj.Cdd.4401106  0.436
2003 Gough PJ, Raines EW. Gene therapy of apolipoprotein E-deficient mice using a novel macrophage-specific retroviral vector. Blood. 101: 485-91. PMID 12393475 DOI: 10.1182/Blood-2002-07-2131  0.307
2002 Dempsey PJ, Garton K, Raines EW. Emerging roles of TACE as a key protease in ErbB ligand shedding. Molecular Interventions. 2: 136-41. PMID 14993373 DOI: 10.1124/Mi.2.3.136  0.701
2002 Tanaka S, Koyama H, Ichii T, Shioi A, Hosoi M, Raines EW, Nishizawa Y. Fibrillar collagen regulation of plasminogen activator inhibitor-1 is involved in altered smooth muscle cell migration. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1573-8. PMID 12377732 DOI: 10.1161/01.Atv.0000028002.60919.4D  0.439
2002 Kozaki K, Kaminski WE, Tang J, Hollenbach S, Lindahl P, Sullivan C, Yu JC, Abe K, Martin PJ, Ross R, Betsholtz C, Giese NA, Raines EW. Blockade of platelet-derived growth factor or its receptors transiently delays but does not prevent fibrous cap formation in ApoE null mice. The American Journal of Pathology. 161: 1395-407. PMID 12368212 DOI: 10.1016/S0002-9440(10)64415-X  0.402
2002 Ham C, Levkau B, Raines EW, Herren B. ADAM15 is an adherens junction molecule whose surface expression can be driven by VE-cadherin. Experimental Cell Research. 279: 239-47. PMID 12243749 DOI: 10.1006/Excr.2002.5606  0.447
2002 Garton KJ, Ferri N, Raines EW. Efficient expression of exogenous genes in primary vascular cells using IRES-based retroviral vectors. Biotechniques. 32: 830, 832, 834 passim. PMID 11962605 DOI: 10.2144/02324Rr01  0.752
2002 Motamed K, Funk SE, Koyama H, Ross R, Raines EW, Sage EH. Inhibition of PDGF-stimulated and matrix-mediated proliferation of human vascular smooth muscle cells by SPARC is independent of changes in cell shape or cyclin-dependent kinase inhibitors. Journal of Cellular Biochemistry. 84: 759-71. PMID 11835401 DOI: 10.1002/Jcb.10095  0.479
2001 Lepidi S, Kenagy RD, Raines EW, Chiu ES, Chait A, Ross R, Clowes AW. MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. Journal of Vascular Surgery. 34: 1111-8. PMID 11743569 DOI: 10.1067/Mva.2001.119401  0.378
2001 Herren B, Garton KJ, Coats S, Bowen-Pope DF, Ross R, Raines EW. ADAM15 overexpression in NIH3T3 cells enhances cell-cell interactions. Experimental Cell Research. 271: 152-60. PMID 11697891 DOI: 10.1006/Excr.2001.5353  0.767
2001 Buetow BS, Crosby JR, Kaminski WE, Ramachandran RK, Lindahl P, Martin P, Betsholtz C, Seifert RA, Raines EW, Bowen-Pope DF. Platelet-derived growth factor B-chain of hematopoietic origin is not necessary for granulation tissue formation and its absence enhances vascularization. The American Journal of Pathology. 159: 1869-76. PMID 11696447 DOI: 10.1016/S0002-9440(10)63033-7  0.391
2001 Garton KJ, Gough PJ, Blobel CP, Murphy G, Greaves DR, Dempsey PJ, Raines EW. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). The Journal of Biological Chemistry. 276: 37993-8001. PMID 11495925 DOI: 10.1074/Jbc.M106434200  0.758
2001 Kaminski WE, Lindahl P, Lin NL, Broudy VC, Crosby JR, Hellström M, Swolin B, Bowen-Pope DF, Martin PJ, Ross R, Betsholtz C, Raines EW. Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice. Blood. 97: 1990-8. PMID 11264163 DOI: 10.1182/Blood.V97.7.1990  0.369
2001 Ichii T, Koyama H, Tanaka S, Kim S, Shioi A, Okuno Y, Raines EW, Iwao H, Otani S, Nishizawa Y. Fibrillar collagen specifically regulates human vascular smooth muscle cell genes involved in cellular responses and the pericellular matrix environment. Circulation Research. 88: 460-7. PMID 11249868 DOI: 10.1161/01.Res.88.5.460  0.437
2001 Levkau B, Garton KJ, Ferri N, Kloke K, Nofer JR, Baba HA, Raines EW, Breithardt G. xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells. Circulation Research. 88: 282-90. PMID 11179195 DOI: 10.1161/01.Res.88.3.282  0.77
2000 Crosby JR, Kaminski WE, Schatteman G, Martin PJ, Raines EW, Seifert RA, Bowen-Pope DF. Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circulation Research. 87: 728-30. PMID 11055974 DOI: 10.1161/01.Res.87.9.728  0.343
2000 Raines EW. The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease. International Journal of Experimental Pathology. 81: 173-82. PMID 10971738 DOI: 10.1046/J.1365-2613.2000.00155.X  0.438
2000 Raines EW, Koyama H, Carragher NO. The extracellular matrix dynamically regulates smooth muscle cell responsiveness to PDGF. Annals of the New York Academy of Sciences. 902: 39-51; discussion 51. PMID 10865824 DOI: 10.1111/J.1749-6632.2000.Tb06299.X  0.405
1999 Levkau B, Scatena M, Giachelli CM, Ross R, Raines EW. Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop Nature Cell Biology. 1: 227-233. PMID 10559921 DOI: 10.1038/12050  0.361
1999 Carragher NO, Levkau B, Ross R, Raines EW. Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin. The Journal of Cell Biology. 147: 619-30. PMID 10545505 DOI: 10.1083/Jcb.147.3.619  0.4
1998 Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of cdk2: Role of a caspase cascade Molecular Cell. 1: 553-563. PMID 9660939 DOI: 10.1016/S1097-2765(00)80055-6  0.361
1998 Herren B, Levkau B, Raines EW, Ross R. Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Molecular Biology of the Cell. 9: 1589-601. PMID 9614196 DOI: 10.1091/Mbc.9.6.1589  0.437
1998 Nakashima Y, Raines EW, Plump AS, Breslow JL, Ross R. Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 842-51. PMID 9598845 DOI: 10.1161/01.Atv.18.5.842  0.387
1998 Levkau B, Herren B, Koyama H, Ross R, Raines EW. Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis. The Journal of Experimental Medicine. 187: 579-86. PMID 9463408 DOI: 10.1084/Jem.187.4.579  0.427
1997 Bornfeldt KE, Campbell JS, Koyama H, Argast GM, Leslie CC, Raines EW, Krebs EG, Ross R. The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets. The Journal of Clinical Investigation. 100: 875-85. PMID 9259587 DOI: 10.1172/Jci119603  0.431
1997 Herren B, Raines EW, Ross R. Three putative integrin ligands identified in human aortic smooth muscle cells. Annals of the New York Academy of Sciences. 811: 498-505. PMID 9186628 DOI: 10.1111/J.1749-6632.1997.Tb52032.X  0.342
1997 Betsholtz C, Raines EW. Platelet-derived growth factor: a key regulator of connective tissue cells in embryogenesis and pathogenesis. Kidney International. 51: 1361-9. PMID 9150445 DOI: 10.1038/Ki.1997.186  0.433
1997 Herren B, Raines EW, Ross R. Expression of a disintegrin-like protein in cultured human vascular cells and in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 173-80. PMID 9039960 DOI: 10.1096/Fasebj.11.2.9039960  0.466
1997 Koyama H, Raines EW, Bornfeldt KE, Roberts JM, Ross R. Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors. Cell. 87: 1069-78. PMID 8978611 DOI: 10.1016/S0092-8674(00)81801-2  0.375
1996 Raines EW, Ross R. Multiple growth factors are associated with lesions of atherosclerosis: specificity or redundancy? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 271-82. PMID 8967895 DOI: 10.1002/Bies.950180405  0.337
1996 Graves LM, Bornfeldt KE, Sidhu JS, Argast GM, Raines EW, Ross R, Leslie CC, Krebs EG. Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells. The Journal of Biological Chemistry. 271: 505-11. PMID 8550611 DOI: 10.1074/Jbc.271.1.505  0.384
1995 Raines EW, Ross R. Biology of atherosclerotic plaque formation: possible role of growth factors in lesion development and the potential impact of soy. The Journal of Nutrition. 125: 624S-630S. PMID 7884544 DOI: 10.1093/Jn/125.Suppl_3.624S  0.496
1995 Bornfeldt KE, Graves LM, Raines EW, Igarashi Y, Wayman G, Yamamura S, Yatomi Y, Sidhu JS, Krebs EG, Hakomori S. Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. The Journal of Cell Biology. 130: 193-206. PMID 7790372 DOI: 10.1083/Jcb.130.1.193  0.382
1995 Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: Role of αvβ3 in smooth muscle cell migration to osteopontin in vitro Journal of Clinical Investigation. 95: 713-724. PMID 7532190 DOI: 10.1172/Jci117718  0.445
1995 Bornfeldt KE, Raines EW, Graves LM, Skinner MP, Krebs EG, Ross R. Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation. Annals of the New York Academy of Sciences. 766: 416-30. PMID 7486687 DOI: 10.1111/J.1749-6632.1995.Tb26691.X  0.41
1994 Nakano T, Raines EW, Abraham JA, Klagsbrun M, Ross R. Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes. Proceedings of the National Academy of Sciences of the United States of America. 91: 1069-73. PMID 8302833 DOI: 10.1073/Pnas.91.3.1069  0.419
1994 Nakashima Y, Plump AS, Raines EW, Breslow JL, Ross R. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 14: 133-40. PMID 8274468 DOI: 10.1161/01.Atv.14.1.133  0.31
1994 Bornfeldt KE, Raines EW, Nakano T, Graves LM, Krebs EG, Ross R. Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. The Journal of Clinical Investigation. 93: 1266-74. PMID 8132765 DOI: 10.1172/Jci117081  0.364
1993 Raines EW, Ross R. Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis. British Heart Journal. 69: S30-7. PMID 8427762 DOI: 10.1136/Hrt.69.1_Suppl.S30  0.462
1993 Jackson CL, Raines EW, Ross R, Reidy MA. Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 13: 1218-26. PMID 8343497 DOI: 10.1161/01.Atv.13.8.1218  0.413
1993 Kraiss LW, Raines EW, Wilcox JN, Seifert RA, Barrett TB, Kirkman TR, Hart CE, Bowen-Pope DF, Ross R, Clowes AW. Regional expression of the platelet-derived growth factor and its receptors in a primate graft model of vessel wall assembly. The Journal of Clinical Investigation. 92: 338-48. PMID 8326002 DOI: 10.1172/Jci116572  0.392
1993 Graves LM, Bornfeldt KE, Raines EW, Potts BC, Macdonald SG, Ross R, Krebs EG. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 10300-4. PMID 7694289 DOI: 10.1073/Pnas.90.21.10300  0.398
1993 SASAHARA M, ROSS R, RAINES EW. Immuno-study of PDGF, PDGF Receptor and Cell Kinetics in Atherosclerotic Lesions in Nonhuman Primates The Journal of Japan Atherosclerosis Society. 21: 493-496. DOI: 10.5551/Jat1973.21.6-7_493  0.332
1992 Johnson RJ, Raines EW, Floege J, Yoshimura A, Pritzl P, Alpers C, Ross R. Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. The Journal of Experimental Medicine. 175: 1413-6. PMID 1569407 DOI: 10.1084/JEM.175.5.1413  0.323
1992 Raines EW, Lane TF, Iruela-Arispe ML, Ross R, Sage EH. The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 1281-5. PMID 1311092 DOI: 10.1073/Pnas.89.4.1281  0.42
1992 Raines EW, Ross R. Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences. The Journal of Cell Biology. 116: 533-43. PMID 1309814 DOI: 10.1083/Jcb.116.2.533  0.323
1991 Ross R, Masuda J, Raines EW. Cellular interactions, growth factors, and smooth muscle proliferation in atherogenesis. Annals of the New York Academy of Sciences. 598: 102-12. PMID 2248430 DOI: 10.1111/J.1749-6632.1990.Tb42282.X  0.323
1991 Ferns GA, Sprugel KH, Seifert RA, Bowen-Pope DF, Kelly JD, Murray M, Raines EW, Ross R. Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF. Growth Factors (Chur, Switzerland). 3: 315-24. PMID 2175209 DOI: 10.3109/08977199009003674  0.418
1991 Sasahara M, Fries JW, Raines EW, Gown AM, Westrum LE, Frosch MP, Bonthron DT, Ross R, Collins T. PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell. 64: 217-27. PMID 1986868 DOI: 10.1016/0092-8674(91)90223-L  0.308
1991 Golden MA, Au YP, Kirkman TR, Wilcox JN, Raines EW, Ross R, Clowes AW. Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation. The Journal of Clinical Investigation. 87: 406-14. PMID 1825089 DOI: 10.1172/Jci115011  0.4
1991 Ferns GA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science (New York, N.Y.). 253: 1129-32. PMID 1653454 DOI: 10.1126/Science.1653454  0.371
1990 Ross R, Masuda J, Raines EW, Gown AM, Katsuda S, Sasahara M, Malden LT, Masuko H, Sato H. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science (New York, N.Y.). 248: 1009-12. PMID 2343305 DOI: 10.1126/Science.2343305  0.421
1990 Battegay EJ, Raines EW, Seifert RA, Bowen-Pope DF, Ross R. TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell. 63: 515-24. PMID 2171777 DOI: 10.1016/0092-8674(90)90448-N  0.314
1990 Dower SK, Qwarnstrom EE, Page RC, Blanton RA, Kupper TS, Raines E, Ross R, Sims JE. Biology of the interleukin-1 receptor. The Journal of Investigative Dermatology. 94: 68S-73S. PMID 2141050 DOI: 10.1111/1523-1747.Ep12875154  0.325
1990 Ross R, Bowen-Pope DF, Raines EW. Platelet-derived growth factor and its role in health and disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 327: 155-69. PMID 1969656 DOI: 10.1098/Rstb.1990.0051  0.457
1990 Cashman J, Eaves A, Raines E, Ross R, Eaves C. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta Blood. 75: 96-101. DOI: 10.1182/Blood.V75.1.96.Bloodjournal75196  0.418
1989 Ross R, Raines EW. Platelet-derived growth factor--its role in health and disease. Advances in Experimental Medicine and Biology. 234: 9-21. PMID 3063091 DOI: 10.1007/978-1-4757-1980-2_2  0.376
1989 Raines EW, Dower SK, Ross R. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science (New York, N.Y.). 243: 393-6. PMID 2783498 DOI: 10.1126/Science.2783498  0.371
1989 Sakariassen KS, Powell JS, Raines EW, Ross R. Selective expression of mRNA encoding platelet-derived growth factor B chain following transfection of foreign genes into cell lines derived from baby hamster kidney Journal of Cellular Biochemistry. 39: 87-94. PMID 2654148 DOI: 10.1002/Jcb.240390110  0.359
1988 Hamerman D, Taylor S, Kirschenbaum I, Klagsbrun M, Raines EW, Ross R, Thomas KA. Growth factors with heparin binding affinity in human synovial fluid. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 186: 384-9. PMID 3423022 DOI: 10.3181/00379727-186-3-Rc2  0.33
1988 Madtes DK, Raines EW, Sakariassen KS, Assoian RK, Sporn MB, Bell GI, Ross R. Induction of transforming growth factor-alpha in activated human alveolar macrophages. Cell. 53: 285-93. PMID 3258795 DOI: 10.1016/0092-8674(88)90390-X  0.379
1987 Papayannopoulou T, Raines E, Collins S, Nakamoto B, Tweeddale M, Ross R. Constitutive and inducible secretion of platelet-derived growth factor analogs by human leukemic cell lines coexpressing erythroid and megakaryocytic markers. The Journal of Clinical Investigation. 79: 859-66. PMID 3469217 DOI: 10.1172/Jci112895  0.365
1987 Assoian RK, Fleurdelys BE, Stevenson HC, Miller PJ, Madtes DK, Raines EW, Ross R, Sporn MB. Expression and secretion of type beta transforming growth factor by activated human macrophages. Proceedings of the National Academy of Sciences of the United States of America. 84: 6020-4. PMID 2888109 DOI: 10.1073/Pnas.84.17.6020  0.326
1987 Raines EW, Ross R. Identification and assay of platelet-derived growth factor-binding proteins. Methods in Enzymology. 147: 48-64. PMID 2823055 DOI: 10.1016/0076-6879(87)47098-5  0.398
1986 Ross R, Bowen-Pope DF, Raines EW. Platelets, macrophages, endothelium, and growth factors. Their effects upon cells and their possible roles in atherogenesis. Annals of the New York Academy of Sciences. 454: 254-60. PMID 3907465 DOI: 10.1111/J.1749-6632.1985.Tb11865.X  0.405
1986 Shimokado K, Raines EW, Madtes DK, Barrett TB, Benditt EP, Ross R. A significant part of macrophage-derived growth factor consists of at least two forms of PDGF. Cell. 43: 277-86. PMID 2416458 DOI: 10.1016/0092-8674(85)90033-9  0.449
1985 Delwiche F, Raines E, Powell J, Ross R, Adamson J. Platelet-derived growth factor enhances in vitro erythropoiesis via stimulation of mesenchymal cells. The Journal of Clinical Investigation. 76: 137-42. PMID 4019772 DOI: 10.1172/Jci111936  0.411
1985 Raines EW, Ross R. Purification of human platelet-derived growth factor. Methods in Enzymology. 109: 749-73. PMID 3990574 DOI: 10.1016/0076-6879(85)09128-5  0.431
1985 Libby P, Raines EW, Cullinane PM, Ross R. Analysis of the mitogenic effect of fetuin preparations on arterial smooth muscle cells: the role of contaminant platelet-derived growth factor. Journal of Cellular Physiology. 125: 357-66. PMID 2415538 DOI: 10.1002/Jcp.1041250302  0.401
1984 Raines EW, Bowen-Pope DF, Ross R. Plasma binding proteins for platelet-derived growth factor that inhibit its binding to cell-surface receptors. Proceedings of the National Academy of Sciences of the United States of America. 81: 3424-8. PMID 6203121 DOI: 10.1073/Pnas.81.11.3424  0.329
1983 Ross R, Raines E, Bowen-Pope D. Growth factors from platelets, monocytes, and endothelium: their role in cell proliferation. Annals of the New York Academy of Sciences. 397: 18-24. PMID 6818881 DOI: 10.1111/J.1749-6632.1982.Tb43413.X  0.375
1983 Cooper JA, Bowen-Pope DF, Raines E, Ross R, Hunter T. Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins. Cell. 31: 263-73. PMID 6186382 DOI: 10.1016/0092-8674(82)90426-3  0.381
1980 Vogel A, Ross R, Raines E. Role of serum components in density-dependent inhibition of growth of cells in culture. Platelet-derived growth factor is the major serum determinant of saturation density. The Journal of Cell Biology. 85: 377-85. PMID 7372711 DOI: 10.1083/Jcb.85.2.377  0.378
1978 Vogel A, Raines E, Kariya B, Rivest MJ, Ross R. Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components. Proceedings of the National Academy of Sciences of the United States of America. 75: 2810-4. PMID 275851 DOI: 10.1073/Pnas.75.6.2810  0.381
1978 Ross R, Nist C, Kariya B, Rivest MJ, Raines E, Callis J. Physiological quiescence in plasma-derived serum: Influence of platelet-derived growth factor on cell growth in culture Journal of Cellular Physiology. 97: 497-508. PMID 103885 DOI: 10.1002/Jcp.1040970325  0.379
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