Farah Sheikh, Ph.D. - Publications

Affiliations: 
2001 University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Animal Physiology Biology, Cell Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang J, Zanella F, Lyon R, Mezzano V, Roberts J, Ursell P, Carromeu C, Gu Y, Martin J, Muotri AR, Scheinman M, Peterson KL, Sheikh F. Connexin43 as a Therapeutic To Restore Cardiac Structure in Arrhythmogenic Heart Disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06280  0.407
2018 Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ. Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. The Journal of Cell Biology. PMID 29959233 DOI: 10.1083/Jcb.201710161  0.33
2018 Liang Y, Bradford WH, Zhang J, Sheikh F. Four and a half LIM domain protein signaling and cardiomyopathy. Biophysical Reviews. PMID 29926425 DOI: 10.1007/S12551-018-0434-3  0.463
2018 Krysiak J, Unger A, Beckendorf L, Hamdani N, von Frieling-Salewsky M, Redfield MM, Dos Remedios CG, Sheikh F, Gergs U, Boknik P, Linke WA. Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes. Nature Communications. 9: 262. PMID 29343782 DOI: 10.1038/S41467-017-02483-3  0.348
2017 Bradford WH, Omens JH, Sheikh F. Vinculin at the heart of aging. Annals of Translational Medicine. 5: 62. PMID 28251141 DOI: 10.21037/Atm.2017.01.65  0.42
2016 Mezzano V, Liang Y, Wright AT, Lyon RC, Pfeiffer E, Song MY, Gu Y, Dalton ND, Scheinman M, Peterson KL, Evans SM, Fowler S, Cerrone M, McCulloch AD, Sheikh F. Desmosomal Junctions Are Necessary for Adult Sinus Node Function. Cardiovascular Research. PMID 27097650 DOI: 10.1093/Cvr/Cvw083  0.301
2016 Pellman J, Zhang J, Sheikh F. Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems. Journal of Molecular and Cellular Cardiology. PMID 26996756 DOI: 10.1016/J.Yjmcc.2016.03.005  0.411
2016 Liang Y, Sheikh F. Scaffold Proteins Regulating Extracellular Regulated Kinase Function in Cardiac Hypertrophy and Disease. Frontiers in Pharmacology. 7: 37. PMID 26973524 DOI: 10.3389/Fphar.2016.00037  0.437
2016 Zanella F, Sheikh F. Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization of Cardiac Cells. Methods in Molecular Biology (Clifton, N.J.). 1353: 147-62. PMID 25520292 DOI: 10.1007/7651_2014_172  0.394
2015 Sheikh F, Lyon RC, Chen J. Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease. Gene. 569: 14-20. PMID 26074085 DOI: 10.1016/J.Gene.2015.06.027  0.448
2015 Mastrototaro G, Liang X, Li X, Carullo P, Piroddi N, Tesi C, Gu Y, Dalton ND, Peterson KL, Poggesi C, Sheikh F, Chen J, Bang ML. Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers. Cardiovascular Research. 107: 216-25. PMID 25987543 DOI: 10.1093/Cvr/Cvv156  0.425
2015 Pellman J, Sheikh F. Atrial fibrillation: mechanisms, therapeutics, and future directions. Comprehensive Physiology. 5: 649-65. PMID 25880508 DOI: 10.1002/Cphy.C140047  0.344
2015 Lyon RC, Zanella F, Omens JH, Sheikh F. Mechanotransduction in cardiac hypertrophy and failure. Circulation Research. 116: 1462-76. PMID 25858069 DOI: 10.1161/Circresaha.116.304937  0.423
2015 Pellman J, Sheikh F. A new mechanism links preamyloid oligomer formation in the myocyte stress response associated with atrial fibrillation. Journal of Molecular and Cellular Cardiology. 80: 110-3. PMID 25541246 DOI: 10.1016/J.Yjmcc.2014.12.005  0.367
2015 Sheikh F, Lyon RC, Chen J. Corrigendum to "Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease" [Gene, 569, (2015), 14-20], doi: 10.1016/j.gene.2015.06.027 Gene. 571: 151. DOI: 10.1016/J.Gene.2015.07.076  0.318
2014 Mezzano V, Pellman J, Sheikh F. Cell junctions in the specialized conduction system of the heart. Cell Communication & Adhesion. 21: 149-59. PMID 24738884 DOI: 10.3109/15419061.2014.905928  0.373
2014 Lyon RC, Mezzano V, Wright AT, Pfeiffer E, Chuang J, Banares K, Castaneda A, Ouyang K, Cui L, Contu R, Gu Y, Evans SM, Omens JH, Peterson KL, McCulloch AD, ... Sheikh F, et al. Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Human Molecular Genetics. 23: 1134-50. PMID 24108106 DOI: 10.1093/Hmg/Ddt508  0.408
2014 Zanella F, Lyon RC, Sheikh F. Modeling heart disease in a dish: from somatic cells to disease-relevant cardiomyocytes. Trends in Cardiovascular Medicine. 24: 32-44. PMID 24054750 DOI: 10.1016/J.Tcm.2013.06.002  0.397
2014 Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, et al. Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Human Molecular Genetics. 23: 209-25. PMID 23975679 DOI: 10.1093/Hmg/Ddt412  0.326
2014 Sheikh F, Lyon RC, Chen J. Getting the skinny on thick filament regulation in cardiac muscle biology and disease. Trends in Cardiovascular Medicine. 24: 133-41. PMID 23968570 DOI: 10.1016/J.Tcm.2013.07.004  0.42
2013 Lin C, Guo X, Lange S, Liu J, Ouyang K, Yin X, Jiang L, Cai Y, Mu Y, Sheikh F, Ye S, Chen J, Ke Y, Cheng H. Cypher/ZASP is a novel A-kinase anchoring protein. The Journal of Biological Chemistry. 288: 29403-13. PMID 23996002 DOI: 10.1074/Jbc.M113.470708  0.301
2013 Lyon RC, Lange S, Sheikh F. Breaking down protein degradation mechanisms in cardiac muscle. Trends in Molecular Medicine. 19: 239-49. PMID 23453282 DOI: 10.1016/J.Molmed.2013.01.005  0.417
2013 Cooley N, Ouyang K, McMullen JR, Kiriazis H, Sheikh F, Wu W, Mu Y, Du XJ, Chen J, Woodcock EA. No Contribution of IP3-R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy Circulation: Heart Failure. 6: 318-325. PMID 23258573 DOI: 10.1161/Circheartfailure.112.972158  0.305
2013 Rao N, Evans S, Stewart D, Spencer KH, Sheikh F, Hui EE, Christman KL. Fibroblasts influence muscle progenitor differentiation and alignment in contact independent and dependent manners in organized co-culture devices. Biomedical Microdevices. 15: 161-9. PMID 22983793 DOI: 10.1007/S10544-012-9709-9  0.364
2012 Raskin A, Lange S, Banares K, Lyon RC, Zieseniss A, Lee LK, Yamazaki KG, Granzier HL, Gregorio CC, McCulloch AD, Omens JH, Sheikh F. A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. The Journal of Biological Chemistry. 287: 29273-84. PMID 22778266 DOI: 10.1074/Jbc.M112.372839  0.406
2012 DeQuach JA, Lin JE, Cam C, Hu D, Salvatore MA, Sheikh F, Christman KL. Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. European Cells & Materials. 23: 400-12; discussion 4. PMID 22665162 DOI: 10.22203/Ecm.V023A31  0.315
2012 Sheikh F, Ouyang K, Campbell SG, Lyon RC, Chuang J, Fitzsimons D, Tangney J, Hidalgo CG, Chung CS, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens JH, et al. Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. The Journal of Clinical Investigation. 122: 1209-21. PMID 22426213 DOI: 10.1172/Jci61134  0.429
2012 Mezzano V, Sheikh F. Cell-cell junction remodeling in the heart: possible role in cardiac conduction system function and arrhythmias? Life Sciences. 90: 313-21. PMID 22227473 DOI: 10.1016/J.Lfs.2011.12.009  0.437
2011 Cheng H, Zheng M, Peter AK, Kimura K, Li X, Ouyang K, Shen T, Cui L, Frank D, Dalton ND, Gu Y, Frey N, Peterson KL, Evans SM, Knowlton KU, ... Sheikh F, et al. Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Human Molecular Genetics. 20: 1751-62. PMID 21303826 DOI: 10.1093/Hmg/Ddr050  0.436
2010 Lu SY, Jin Y, Li X, Sheppard P, Bock ME, Sheikh F, Duckworth ML, Cattini PA. Embryonic survival and severity of cardiac and craniofacial defects are affected by genetic background in fibroblast growth factor-16 null mice. Dna and Cell Biology. 29: 407-15. PMID 20618076 DOI: 10.1089/Dna.2010.1024  0.656
2010 Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N. Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circulation Research. 106: 880-90. PMID 20093627 DOI: 10.1161/Circresaha.109.213256  0.464
2010 Pellman J, Lyon RC, Sheikh F. Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. Journal of Molecular and Cellular Cardiology. 48: 461-7. PMID 19751740 DOI: 10.1016/J.Yjmcc.2009.09.001  0.352
2009 Sheikh F, Ross RS, Chen J. Cell-cell connection to cardiac disease. Trends in Cardiovascular Medicine. 19: 182-90. PMID 20211433 DOI: 10.1016/J.Tcm.2009.12.001  0.41
2009 Princen F, Bard E, Sheikh F, Zhang SS, Wang J, Zago WM, Wu D, Trelles RD, Bailly-Maitre B, Kahn CR, Chen Y, Reed JC, Tong GG, Mercola M, Chen J, et al. Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death. Molecular and Cellular Biology. 29: 378-88. PMID 19001090 DOI: 10.1128/Mcb.01661-08  0.354
2008 Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW, Brown JH, Heller-Brown J, et al. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. The Journal of Clinical Investigation. 118: 3870-80. PMID 19033658 DOI: 10.1172/Jci34472  0.36
2008 Lu SY, Sheikh F, Sheppard PC, Fresnoza A, Duckworth ML, Detillieux KA, Cattini PA. FGF-16 is required for embryonic heart development. Biochemical and Biophysical Research Communications. 373: 270-4. PMID 18565327 DOI: 10.1016/J.Bbrc.2008.06.029  0.683
2007 Sheikh F, Bang ML, Lange S, Chen J. "Z"eroing in on the role of Cypher in striated muscle function, signaling, and human disease. Trends in Cardiovascular Medicine. 17: 258-62. PMID 18021935 DOI: 10.1016/J.Tcm.2007.09.002  0.332
2007 Gawaziuk JP, X, Sheikh F, Cheng ZQ, Cattini PA, Stephens NL. Transforming growth factor-beta as a differentiating factor for cultured smooth muscle cells. The European Respiratory Journal. 30: 643-52. PMID 17596270 DOI: 10.1183/09031936.00141805  0.556
2007 Sheikh F, Chen J. Mouse models for cardiomyopathy research Progress in Pediatric Cardiology. 24: 27-34. DOI: 10.1016/J.Ppedcard.2007.08.006  0.399
2004 Sheikh F, Hirst CJ, Jin Y, Bock ME, Fandrich RR, Nickel BE, Doble BW, Kardami E, Cattini PA. Inhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesis. Cardiovascular Research. 64: 516-25. PMID 15537505 DOI: 10.1016/J.Cardiores.2004.08.009  0.63
2004 Kardami E, Jiang ZS, Jimenez SK, Hirst CJ, Sheikh F, Zahradka P, Cattini PA. Fibroblast growth factor 2 isoforms and cardiac hypertrophy. Cardiovascular Research. 63: 458-66. PMID 15276471 DOI: 10.1016/J.Cardiores.2004.04.024  0.69
2004 Jimenez SK, Sheikh F, Jin Y, Detillieux KA, Dhaliwal J, Kardami E, Cattini PA. Transcriptional regulation of FGF-2 gene expression in cardiac myocytes. Cardiovascular Research. 62: 548-57. PMID 15158147 DOI: 10.1016/J.Cardiores.2004.01.032  0.668
2003 Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J. Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis. Development (Cambridge, England). 130: 6111-9. PMID 14573518 DOI: 10.1242/Dev.00831  0.439
2003 Detillieux KA, Sheikh F, Kardami E, Cattini PA. Biological activities of fibroblast growth factor-2 in the adult myocardium. Cardiovascular Research. 57: 8-19. PMID 12504809 DOI: 10.1016/S0008-6363(02)00708-3  0.684
2003 Huang C, Zhou Q, Liang P, Hollander MS, Sheikh F, Li X, Greaser M, Shelton GD, Evans S, Chen J. Characterization and in vivo functional analysis of splice variants of cypher. The Journal of Biological Chemistry. 278: 7360-5. PMID 12499364 DOI: 10.1074/Jbc.M211875200  0.383
2002 Meij JTA, Sheikh F, Jimenez SK, Nickerson PW, Kardami E, Cattini PA. Exacerbation of myocardial injury in transgenic mice overexpressing FGF-2 is T cell dependent American Journal of Physiology - Heart and Circulatory Physiology. 282: H547-H555. PMID 11788402 DOI: 10.1152/Ajpheart.01019.2000  0.681
2002 Jimenez S, Sheikh F, Detillieux K, Dhaliwal J, Kardami E, Cattini P. 09 β-adrenergic stimulation increases FGF-2 promoter activity in transgenic mouse hearts Journal of Molecular and Cellular Cardiology. 34: A41. DOI: 10.1016/S0022-2828(02)90217-8  0.622
2001 Sheikh F, Sontag DP, Fandrich RR, Kardami E, Cattini PA. Overexpression of FGF-2 increases cardiac myocyte viability after injury in isolated mouse hearts. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1039-50. PMID 11179045 DOI: 10.1152/Ajpheart.2001.280.3.H1039  0.689
2001 Jimenez S, Sheikh F, Meij J, Nickerson P, Kardami E, Cattini P. Increased lesion size and nuclear infiltration are seen in FGF-2 transgenic mouse hearts after ischemic injury in vivo Journal of Molecular and Cellular Cardiology. 33: A54. DOI: 10.1016/S0022-2828(01)90213-5  0.613
2001 Agustin C, Sheikh F, Herlyn M, Cattini PA, Kardami E. Intracrine effects of CUG-initiated FGF-2 on chromatin precede development of apoptotic DNA ladder in cardiomyocytes Journal of Molecular and Cellular Cardiology. 33: A2. DOI: 10.1016/S0022-2828(01)90006-9  0.584
2000 Jin Y, Sheikh F, Detillieux KA, Cattini PA. Role for early growth response-1 protein in alpha(1)-adrenergic stimulation of fibroblast growth factor-2 promoter activity in cardiac myocytes. Molecular Pharmacology. 57: 984-90. PMID 10779383  0.628
1999 Sheikh F, Fandrich RR, Kardami E, Cattini PA. Overexpression of long or short FGFR-1 results in FGF-2-mediated proliferation in neonatal cardiac myocyte cultures. Cardiovascular Research. 42: 696-705. PMID 10533610 DOI: 10.1016/S0008-6363(99)00008-5  0.676
1999 Nickerson P, Meij J, Sheikh F, Kardami E, Cattini PA. ISCHEMIA INDUCED MYOCARDIAL INJURY IS ACCENTUATED IN TRANSGENIC MICE OVEREXPRESSING FGF-2 AND IS LINKED TO A T-CELL DEPENDENT PROCESS. Transplantation. 67: S36. DOI: 10.1097/00007890-199904150-00146  0.574
1998 Cattini PA, Jin Y, Sheikh F. Detection of 28S RNA with the FGF-2 cDNA at high stringency through related G/C-rich sequences. Molecular and Cellular Biochemistry. 189: 33-9. PMID 9879651 DOI: 10.1023/A:1006852312188  0.594
1997 Sheikh F, Jin Y, Pasumarthi KB, Kardami E, Cattini PA. Expression of fibroblast growth factor receptor-1 in rat heart H9c2 myoblasts increases cell proliferation. Molecular and Cellular Biochemistry. 176: 89-97. PMID 9406149 DOI: 10.1023/A:1006879029333  0.644
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