Gianfranco Alpini - Publications

Affiliations: 
The Texas A&M University System Health Science Center 
Area:
Molecular Biology, Physiology Biology

498 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Medford A, Childs J, Little A, Chakraborty S, Baiocchi L, Alpini G, Glaser S. Emerging Therapeutic Strategies in The Fight Against Primary Biliary Cholangitis. Journal of Clinical and Translational Hepatology. 11: 949-957. PMID 37408803 DOI: 10.14218/JCTH.2022.00398  0.511
2023 Ceci L, Han Y, Krutsinger K, Baiocchi L, Wu N, Kundu D, Kyritsi K, Zhou T, Gaudio E, Francis H, Alpini G, Kennedy L. Gallstone and Gallbladder Disease: Biliary Tract and Cholangiopathies. Comprehensive Physiology. 13: 4909-4943. PMID 37358507 DOI: 10.1002/cphy.c220028  0.301
2023 Zhang W, Kyritsi K, Isidan A, Park Y, Li P, Cross-Najafi AA, Lopez K, Kennedy L, Sato K, Glaser S, Francis H, Alpini G, Ekser B. Development of Scaffold-free 3D Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis. The American Journal of Pathology. PMID 37263345 DOI: 10.1016/j.ajpath.2023.05.005  0.466
2023 Alghoul Z, Sung J, Wu K, Alpini G, Glaser S, Yang C, Merlin D. Preparation and Characterization of IL-22 mRNA-loaded Lipid Nanoparticles. Bio-Protocol. 13: e4647. PMID 37056242 DOI: 10.21769/BioProtoc.4647  0.371
2023 Kundu D, Kennedy L, Zhou T, Ekser B, Meadows V, Sybenga A, Kyritsi K, Chen L, Ceci L, Wu N, Wu C, Glaser S, Carpino G, Onori P, Gaudio E, ... Alpini G, et al. p16 INK4A drives non-alcoholic fatty liver disease phenotypes in high fat diet fed mice via biliary e2f1/foxo1/igf-1 signaling. Hepatology (Baltimore, Md.). PMID 36799449 DOI: 10.1097/HEP.0000000000000307  0.496
2023 Wu N, Zhou T, Carpino G, Baiocchi L, Kyritsi K, Kennedy L, Ceci L, Chen L, Wu C, Kundu D, Barupala N, Franchitto A, Onori P, Ekser B, Gaudio E, ... ... Alpini G, et al. Prolonged administration of a secretin receptor antagonist inhibits biliary senescence and liver fibrosis in Mdr2-/- mice. Hepatology (Baltimore, Md.). PMID 36799446 DOI: 10.1097/HEP.0000000000000310  0.544
2023 Zhu B, Guo X, Xu H, Jiang B, Li H, Wang Y, Yin Q, Zhou T, Cai JJ, Glaser S, Meng F, Francis H, Alpini G, Wu C. Adipose tissue inflammation and systemic insulin resistance in mice with diet-induced obesity is possibly associated with disruption of PFKFB3 in hematopoietic cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 328-340. PMID 36775497 DOI: 10.1038/s41374-020-00523-z  0.415
2023 Lewis PL, Su J, Yan M, Meng F, Glaser SS, Alpini GD, Green RM, Sosa-Pineda B, Shah RN. Author Correction: Complex bile duct network formation within liver decellularized extracellular matrix hydrogels. Scientific Reports. 13: 923. PMID 36650181 DOI: 10.1038/s41598-022-26508-0  0.452
2023 Kyritsi K, Wu N, Zhou T, Carpino G, Baiocchi L, Kennedy L, Chen L, Ceci L, Meyer AA, Barupala N, Franchitto A, Onori P, Ekser B, Gaudio E, Wu C, ... ... Alpini G, et al. Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity. Cell & Bioscience. 13: 5. PMID 36624475 DOI: 10.1186/s13578-022-00945-w  0.544
2022 Sato K, Pham L, Glaser S, Francis H, Alpini G. Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis. Cellular and Molecular Gastroenterology and Hepatology. PMID 36435428 DOI: 10.1016/j.jcmgh.2022.11.006  0.507
2022 Yang C, Alpini G, Glaser S, Merlin D. Lipid nanoparticles for oral delivery of nucleic acids for treating inflammatory bowel disease. Nanomedicine (London, England). PMID 36317587 DOI: 10.2217/nnm-2022-0222  0.368
2022 Overi D, Carpino G, Cristoferi L, Onori P, Kennedy L, Francis H, Zucchini N, Rigamonti C, Viganò M, Floreani A, D'Amato D, Gerussi A, Venere R, Alpini G, Glaser S, et al. Role of ductular reaction and ductular-canalicular junctions in identifying severe primary biliary cholangitis. Jhep Reports : Innovation in Hepatology. 4: 100556. PMID 36267871 DOI: 10.1016/j.jhepr.2022.100556  0.487
2022 Li H, Zheng J, Xu Q, Yang Y, Zhou J, Guo X, Cai Y, Cai JJ, Xie L, Awika J, Han X, Li Q, Kennedy L, Francis H, Glaser S, ... ... Alpini G, et al. Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation. Gastroenterology. PMID 36181835 DOI: 10.1053/j.gastro.2022.09.027  0.514
2022 Park Y, Thadasina D, Bolujo I, Isidan A, Cross-Najafi AA, Lopez K, Li P, Dahlem A, Kennedy L, Sato K, Francis H, Alpini G, Zhang W, Ekser B. 3D Organoids as a Model to Study Nonalcoholic Fatty Liver Disease. Seminars in Liver Disease. PMID 36044928 DOI: 10.1055/a-1934-5588  0.318
2022 Kennedy L, Carpino G, Owen T, Ceci L, Kundu D, Meadows V, Kyritsi K, Franchitto A, Onori P, Isidan A, Zhang W, Ekser B, Alvaro D, Gaudio E, Gershwin ME, ... ... Alpini G, et al. Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes. Journal of Hepatology. PMID 35987275 DOI: 10.1016/j.jhep.2022.07.034  0.501
2022 Ceci L, Chen L, Baiocchi L, Wu N, Kennedy L, Carpino G, Kyritsi K, Zhou T, Owen T, Kundu D, Sybenga A, Isidan A, Ekser B, Franchitto A, Onori P, ... ... Alpini G, et al. Prolonged administration of melatonin ameliorates liver phenotypes in cholestatic murine model. Cellular and Molecular Gastroenterology and Hepatology. PMID 35863741 DOI: 10.1016/j.jcmgh.2022.07.007  0.537
2022 Zhou T, Meadows V, Kundu D, Kyritsi K, Owen T, Ceci L, Carpino G, Onori P, Gaudio E, Wu N, Glaser S, Ekser B, Alpini G, Kennedy L, Francis H. Mast cells selectively target large cholangiocytes during biliary injury via H2HR-mediated cAMP/pERK1/2 signaling. Hepatology Communications. PMID 35799467 DOI: 10.1002/hep4.2026  0.542
2022 Isidan A, Yenigun A, Soma D, Aksu E, Lopez K, Park Y, Cross-Najafi A, Li P, Kundu D, House MG, Chakraborty S, Glaser S, Kennedy L, Francis H, Zhang W, ... Alpini G, et al. Development and characterization of human primary cholangiocarcinoma cell lines. The American Journal of Pathology. PMID 35640676 DOI: 10.1016/j.ajpath.2022.05.007  0.429
2022 Zhu B, Li H, Lu B, Guo X, Wu C, Wang F, Li Q, Xie L, Glaser S, Francis H, Alpini G, Wu C. Indole supplementation ameliorates MCD-induced NASH in mice. The Journal of Nutritional Biochemistry. 107: 109041. PMID 35568098 DOI: 10.1016/j.jnutbio.2022.109041  0.541
2022 Mancinelli R, Ceci L, Kennedy L, Francis H, Meadows V, Chen L, Carpino G, Kyritsi K, Wu N, Zhou T, Sato K, Pannarale L, Glaser S, Chakraborty S, Alpini G, et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells. 11. PMID 35563897 DOI: 10.3390/cells11091591  0.546
2022 Han Y, Chen L, Baiocchi L, Ceci L, Glaser S, Francis H, Alpini G, Kennedy L. Circadian Rhythm and Melatonin in Liver Carcinogenesis: Updates on Current Findings. Critical Reviews in Oncogenesis. 26: 69-85. PMID 35377987 DOI: 10.1615/CritRevOncog.2021039881  0.512
2022 Pham L, Kyritsi K, Zhou T, Ceci L, Baiocchi L, Kennedy L, Chakraborty S, Glaser S, Francis H, Alpini G, Sato K. The Functional Roles of Immune Cells in Primary Liver Cancer. The American Journal of Pathology. PMID 35337836 DOI: 10.1016/j.ajpath.2022.02.004  0.465
2022 Ceci L, Zhou T, Lenci I, Meadows V, Kennedy L, Li P, Ekser B, Milana M, Zhang W, Wu C, Sato K, Chakraborty S, Glaser SS, Francis H, Alpini G, et al. Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development. Cancers. 14. PMID 35326593 DOI: 10.3390/cancers14061442  0.442
2022 O'Brien A, Zhou T, White T, Medford A, Chen L, Kyritsi K, Wu N, Childs J, Stiles D, Ceci L, Chakraborty S, Ekser B, Baiocchi L, Carpino G, Gaudio E, ... ... Alpini G, et al. FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2 Mouse Model of Primary Sclerosing Cholangitis. Hepatology Communications. PMID 35271760 DOI: 10.1002/hep4.1909  0.522
2021 Meadows V, Baiocchi L, Kundu D, Sato K, Fuentes Y, Wu C, Chakraborty S, Glaser S, Alpini G, Kennedy L, Francis H. Biliary Epithelial Senescence in Liver Disease: There Will Be SASP. Frontiers in Molecular Biosciences. 8: 803098. PMID 34993234 DOI: 10.3389/fmolb.2021.803098  0.535
2021 Roy S, Kumaravel S, Banerjee P, White TK, O'Brien A, Seelig C, Chauhan R, Ekser B, Bayless KJ, Alpini G, Glaser SS, Chakraborty S. Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma. Cells. 10. PMID 34831316 DOI: 10.3390/cells10113093  0.455
2021 Wu N, Carpino G, Ceci L, Baiocchi L, Francis H, Kennedy L, Zhou T, Chen L, Sato K, Kyritsi K, Meadows V, Ekser B, Franchitto A, Mancinelli R, Onori P, ... ... Alpini G, et al. MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury. Hepatology (Baltimore, Md.). PMID 34743371 DOI: 10.1002/hep.32233  0.482
2021 Roy S, Banerjee P, Ekser B, Bayless K, Zawieja D, Alpini G, Glaser SS, Chakraborty S. Targeting lymphangiogenesis and lymph node metastasis in liver cancer. The American Journal of Pathology. PMID 34509441 DOI: 10.1016/j.ajpath.2021.08.011  0.498
2021 Zhou T, Kundu D, Robles-Linares J, Meadows V, Sato K, Baiocchi L, Ekser B, Glaser S, Alpini G, Francis H, Kennedy L. Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease. Cells. 10. PMID 34440841 DOI: 10.3390/cells10082072  0.514
2021 Pham L, Kennedy L, Baiocchi L, Meadows V, Ekser B, Kundu D, Zhou T, Sato K, Glaser S, Ceci L, Alpini G, Francis H. Mast Cells in Liver Disease Progression: An Update on Current Studies and Implications. Hepatology (Baltimore, Md.). PMID 34435373 DOI: 10.1002/hep.32121  0.547
2021 Baiocchi L, Lenci I, Milana M, Kennedy L, Sato K, Zhang W, Ekser B, Ceci L, Meadows V, Glaser S, Alpini G, Francis H. Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment? Cells. 10. PMID 34359861 DOI: 10.3390/cells10071692  0.507
2021 Sato K, Baiocchi L, Kennedy L, Zhang W, Ekser B, Glaser S, Francis H, Alpini G. Current Advances in Basic and Translational Research of Cholangiocarcinoma. Cancers. 13. PMID 34282753 DOI: 10.3390/cancers13133307  0.414
2021 Baiocchi L, Glaser S, Francis H, Kennedy L, Felli E, Alpini G, Gracia-Sancho J. Impact of Aging on Liver Cells and Liver Disease: Focus on the Biliary and Vascular Compartments. Hepatology Communications. 5: 1125-1137. PMID 34278165 DOI: 10.1002/hep4.1725  0.508
2021 Matthews DR, Li H, Zhou J, Li Q, Glaser S, Francis H, Alpini G, Wu C. Methionine- and Choline-deficient Diet-induced Non-alcoholic Steatohepatitis Is Associated with Increased Intestinal Inflammation. The American Journal of Pathology. PMID 34242656 DOI: 10.1016/j.ajpath.2021.06.010  0.44
2021 Meadows V, Kennedy L, Ekser B, Kyritsi K, Kundu D, Zhou T, Chen L, Pham L, Wu N, Demieville J, Hargrove L, Glaser S, Alpini G, Francis H. Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis via Farnesoid X Receptor Signaling. Hepatology (Baltimore, Md.). PMID 34164827 DOI: 10.1002/hep.32028  0.563
2021 Lepore A, Choy PM, Lee NC, Carella MA, Favicchio R, Briones-Orta MA, Glaser SS, Alpini G, D'Santos C, Tooze RM, Lorger M, Syn WK, Papakyriakou A, Giamas G, Bubici C, et al. Phosphorylation and stabilization of PIN1 by JNK promote intrahepatic cholangiocarcinoma growth. Hepatology (Baltimore, Md.). PMID 34048060 DOI: 10.1002/hep.31983  0.469
2021 Xu H, Zhu B, Li H, Jiang B, Wang Y, Yin Q, Cai J, Glaser S, Francis H, Alpini G, Wu C. Adipocyte Inducible 6-phosphofructo-2-kinase Suppresses Adipose Tissue Inflammation and Promotes Macrophage Anti-inflammatory Activation. The Journal of Nutritional Biochemistry. 108764. PMID 33964465 DOI: 10.1016/j.jnutbio.2021.108764  0.43
2021 Chen L, Wu N, Kennedy L, Francis H, Ceci L, Zhou T, Samala N, Kyritsi K, Wu C, Sybenga A, Ekser B, Dar W, Atkins C, Meadows V, Glaser S, ... Alpini G, et al. Inhibition of secretin/secretin receptor axis ameliorates non-alcoholic fatty liver disease phenotypes. Hepatology (Baltimore, Md.). PMID 33928675 DOI: 10.1002/hep.31871  0.545
2021 Zhu B, Guo X, Xu H, Jiang B, Li H, Wang Y, Yin Q, Zhou T, Cai JJ, Glaser S, Meng F, Francis H, Alpini G, Wu C. Adipose tissue inflammation and systemic insulin resistance in mice with diet-induced obesity is possibly associated with disruption of PFKFB3 in hematopoietic cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 33462362 DOI: 10.1038/s41374-020-00523-z  0.415
2021 Kennedy L, Meadows V, Sybenga A, Demieville J, Chen L, Hargrove L, Ekser B, Dar W, Ceci L, Kundu D, Kyritsi K, Pham L, Zhou T, Glaser S, Meng F, ... Alpini G, et al. Mast Cells Promote Non-Alcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed Western Diet. Hepatology (Baltimore, Md.). PMID 33434322 DOI: 10.1002/hep.31713  0.525
2020 Guo X, Zhu B, Xu H, Li H, Jiang B, Wang Y, Zheng B, Glaser S, Alpini G, Wu C. Adoptive transfer of -disrupted hematopoietic cells to wild-type mice exacerbates diet-induced hepatic steatosis and inflammation. Liver Research. 4: 136-144. PMID 34336366 DOI: 10.1016/j.livres.2020.08.004  0.537
2020 Baiocchi L, Sato K, Ekser B, Kennedy L, Francis H, Ceci L, Lenci I, Alvaro D, Franchitto A, Onori P, Gaudio E, Wu C, Chakraborty S, Glaser S, Alpini G. Cholangiocarcinoma: Bridging the translational gap from preclinical to clinical development and implications for future therapy. Expert Opinion On Investigational Drugs. PMID 33226854 DOI: 10.1080/13543784.2021.1854725  0.419
2020 Sato K, Zhang W, Safarikia S, Isidan A, Chen AM, Li P, Francis H, Kennedy L, Baiocchi L, Alvaro D, Glaser S, Ekser B, Alpini G. Organoids and spheroids as novel models for studying cholestatic liver injury and cholangiocarcinoma. Hepatology (Baltimore, Md.). PMID 33222247 DOI: 10.1002/hep.31653  0.501
2020 Chen L, Zhou T, White T, O'Brien A, Chakraborty S, Liangpunsakul S, Yang Z, Kennedy L, Saxena R, Wu C, Meng F, Huang Q, Francis H, Alpini G, Glaser S. The apelin-apelin receptor axis triggers cholangiocyte proliferation and liver fibrosis during mouse models of cholestasis. Hepatology (Baltimore, Md.). PMID 32964473 DOI: 10.1002/Hep.31545  0.594
2020 Slevin E, Baiocchi L, Wu N, Ekser B, Sato K, Lin E, Ceci L, Chen L, Lorenzo SR, Xu W, Kyritsi K, Meadows V, Zhou T, Kundu D, Han Y, ... ... Alpini G, et al. Kupffer cells: Inflammation pathways and cell-cell interactions in alcohol-associated liver disease. The American Journal of Pathology. PMID 32919978 DOI: 10.1016/J.Ajpath.2020.08.014  0.593
2020 O'Brien A, Gasheva O, Alpini G, Zawieja D, Gashev A, Glaser S. The Role of Lymphatics in Cholestasis: A Comprehensive Review. Seminars in Liver Disease. PMID 32906164 DOI: 10.1055/S-0040-1713675  0.57
2020 Kyritsi K, Kennedy L, Meadows V, Hargrove L, Demieville J, Pham L, Sybenga A, Kundu D, Cerritos K, Meng F, Alpini G, Francis H. Mast cells (MCs) induce ductular reaction mimicking liver injury in mice via MC-derived TGF-β1 signaling. Hepatology (Baltimore, Md.). PMID 32761972 DOI: 10.1002/Hep.31497  0.438
2020 Wu N, Baiocchi L, Zhou T, Kennedy L, Ceci L, Meng F, Sato K, Wu C, Ekser B, Kyritsi K, Kundu D, Chen L, Meadows V, Franchitto A, Alvaro D, ... ... Alpini G, et al. The Functional Role of the Secretin/Secretin Receptor Signaling During Cholestatic Liver Injury. Hepatology (Baltimore, Md.). PMID 32737904 DOI: 10.1002/Hep.31484  0.564
2020 Ceci L, Francis H, Zhou T, Giang T, Yang Z, Meng F, Wu N, Kennedy L, Kyritsi K, Meadows V, Wu C, Liangpunsakul S, Franchitto A, Sybenga A, Ekser B, ... ... Alpini G, et al. Knockout of the tachykinin receptor 1 in the Mdr2 mouse model of primary sclerosing cholangitis reduces biliary damage and liver fibrosis. The American Journal of Pathology. PMID 32712019 DOI: 10.1016/J.Ajpath.2020.07.007  0.534
2020 Fabris L, Sato K, Alpini G, Strazzabosco M. The Tumor Microenvironment in Cholangiocarcinoma Progression. Hepatology (Baltimore, Md.). PMID 32500550 DOI: 10.1002/Hep.31410  0.335
2020 Kyritsi K, Francis H, Zhou T, Ceci L, Wu N, Yhang Z, Meng F, Chen L, Baiocchi L, Kundu D, Kennedy L, Liangpunsakul S, Wu C, Glaser S, Alpini G. Downregulation of p16 decreases biliary damage and liver fibrosis in the Mdr2-/- mouse model of primary sclerosing cholangitis. Gene Expression. PMID 32393417 DOI: 10.3727/105221620X15889714507961  0.551
2020 Glaser T, Baiocchi L, Zhou T, Francis H, Lenci I, Grassi G, Kennedy L, Liangpunsakul S, Glaser S, Alpini G, Meng F. Pro-inflammatory signalling and gut-liver axis in non-alcoholic and alcoholic steatohepatitis: Differences and similarities along the path. Journal of Cellular and Molecular Medicine. PMID 32314869 DOI: 10.1111/Jcmm.15182  0.556
2020 Sato K, Glaser S, Francis H, Alpini G. Concise Review: Functional Roles and Therapeutic Potentials of Long Non-coding RNAs in Cholangiopathies. Frontiers in Medicine. 7: 48. PMID 32154257 DOI: 10.3389/Fmed.2020.00048  0.509
2020 Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. H2 histamine receptor Vivo-Morpholino treatment ameliorates large bile duct damage in mice deficient in ATP binding cassette subfamily B member 4 (Abcb4-/-) via down-regulation of cAMP/ERK signaling. The American Journal of Pathology. PMID 32142732 DOI: 10.1016/J.Ajpath.2020.01.013  0.602
2020 Sato K, Glaser S, Alvaro D, Meng F, Francis H, Alpini G. Cholangiocarcinoma: novel therapeutic targets. Expert Opinion On Therapeutic Targets. 1-13. PMID 32077341 DOI: 10.1080/14728222.2020.1733528  0.497
2020 Sato K, Francis H, Zhou T, Meng F, Kennedy L, Ekser B, Baiocchi L, Onori P, Mancinelli R, Gaudio E, Franchitto A, Glaser S, Alpini G. Neuroendocrine Changes in Cholangiocarcinoma Growth. Cells. 9. PMID 32069926 DOI: 10.3390/Cells9020436  0.545
2020 Meadows V, Kennedy L, Kundu D, Alpini G, Francis H. Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases. Frontiers in Medicine. 7: 15. PMID 32064266 DOI: 10.3389/Fmed.2020.00015  0.414
2020 Sato K, Meng F, Francis H, Wu N, Chen L, Kennedy L, Zhou T, Franchitto A, Onori P, Gaudio E, Glaser S, Alpini G. Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies. Journal of Pineal Research. e12639. PMID 32061110 DOI: 10.1111/Jpi.12639  0.54
2020 Kennedy L, Meadows V, Demieville J, Hargrove L, Virani S, Glaser S, Zhou T, Rinehart E, Jaeger V, Kyritsi K, Pham L, Alpini G, Francis H. Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 32054995 DOI: 10.1038/S41374-020-0405-8  0.564
2020 Ma L, Li H, Hu J, Zheng J, Zhou J, Botchlett R, Matthews D, Zeng T, Chen L, Xiao X, Athrey G, Threadgill D, Li Q, Glaser S, Francis H, ... ... Alpini G, et al. Indole Alleviates Diet-induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell PFKFB3. Hepatology (Baltimore, Md.). PMID 31953865 DOI: 10.1002/Hep.31115  0.581
2020 Wan Y, Ceci L, Wu N, Zhou T, Chen L, Venter J, Francis H, Bernuzzi F, Invernizzi P, Kyritsi K, Baker P, Huang Q, Wu C, Sybenga A, Alpini G, et al. Correction to: Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31937871 DOI: 10.1038/s41374-020-0376-9  0.499
2020 Zhou B, Wan Y, Chen R, Zhang C, Li X, Meng F, Glaser S, Wu N, Zhou T, Li S, Francis H, Alpini G, Zou P. The emerging role of cellular senescence in renal diseases. Journal of Cellular and Molecular Medicine. PMID 31916698 DOI: 10.1111/Jcmm.14952  0.499
2020 Kumar N, Mishra J, Alpini G, Ludovica C, Kyritsi, Konstantina, Glaser S, Meng F, Heather F. Role of Jak3 in hepatic inflammation during ulcerative colitis. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09860  0.341
2020 O’Brien A, Chen L, Cromer W, Alpini G, Glaser S, Zawieja D. Liver fibrosis and biliary proliferation are enhanced in the rat model of inflammatory bowel disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07053  0.578
2020 O’Brien A, White T, Francis H, Meng F, Alpini G, Glaser S. FGF1 receptor antagonist decreases biliary proliferation, fibrosis, and senescence in a mouse model of chronic cholestasis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06501  0.526
2020 Wu N, Zhou T, Chen L, Slevin E, Glaser S, Francis HL, Alpini G, Meng F. microRNA‐34a Knockout Attenuates Endothelial Progenitor Dysfunction in Cholestatic Liver Injury The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05471  0.549
2020 Kennedy L, Francis H, Marzioni M, Invernizzi P, Carbone M, Mancinelli R, Onori P, Franchitto A, Gaudio E, Alvaro D, Gershwin ME, Glaser S, Alpini G. Combined ursodeoxycholic acid/secretin treatment reduces biliary senescence and liver fibrosis in a murine model of late stage primary biliary cholangitis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04591  0.555
2020 Kennedy L, Meadows V, Kundu D, Yang Z, Invernizzi P, Carbone M, Liangpunsakul S, Alpini G, Francis H. Mast Cell (MC) Activation and Histamine (HA) Signaling Promotes Atypical Ductular Reaction, Biliary Senescence and Liver Fibrosis During Advanced Stage Primary Biliary Cholangitis (PBC) The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02713  0.391
2020 Zhou T, Kyritsi K, Huang L, Wu N, McDaniel KM, Yang Z, Sato K, Wu C, Ceci L, Chen L, Francis HL, Glaser SS, Liangpunsakul S, Alpini G, Meng F. Sa1502 PROMOTION OF M1 MACROPHAGE POLARIZATION AND DUCTULAR REACTION BY MICRORNA-34A DURING CHOLESTATIC LIVER INJURY Gastroenterology. 158: S-1313. DOI: 10.1016/S0016-5085(20)33947-0  0.52
2020 Meadows V, Kennedy L, Kundu D, Kyritsi K, Cerritos K, Alpini G, Francis HL. Sa1494 INHIBITION OF BILIARY ASBT VIA VIVO-MORPHOLINO TREATMENT DECREASES MAST CELL ACTIVATION AND SUBSEQUENT BILIARY DAMAGE, HEPATIC FIBROSIS AND BILE ACID SIGNALING IN MDR2-/- MICE Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33939-1  0.41
2020 Kundu D, Meadows V, Kennedy L, Ceci L, Kyritsi K, Chen L, Wu N, Cerritos K, Glaser SS, Alpini G, Francis HL. Sa1493 COORDINATED REGULATION OF SENSORY INNERVATION AND MAST CELL ACTIVATION CONTRIBUTES TO BILIARY DAMAGE AND HEPATIC FIBROSIS Gastroenterology. 158: S-1310. DOI: 10.1016/S0016-5085(20)33938-X  0.56
2020 Sato K, Kyritsi K, Francis HL, Slevin E, Grumbles K, Kennedy L, Wu N, Chen L, Liangpunsakul S, Yang Z, Xu W, Ceci L, Glaser SS, Alpini G, Meng F. Sa1491 CHOLANGIOCARCINOMA CELLS SECRETE EXTRACELLULAR VESICLES THAT CONTRIBUTE TO CYTOKINE EXPRESSION AND FIBROGENESIS DURING THE TUMOR MICROENVIRONMENT DEVELOPMENT. Gastroenterology. 158: S-1309. DOI: 10.1016/S0016-5085(20)33936-6  0.493
2020 Ceci L, Wu N, Francis HL, Chen L, Zhou T, Kennedy L, Kyritsi K, Grumbles K, Rivosecchi-Fulton J, Meadows V, Wu C, Kundu D, Meng F, Franchitto A, Gaudio E, ... ... Alpini G, et al. Sa1490 PROLONGED ADMINISTRATION OF MELATONIN TO THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSIS CHOLANGITIS (PSC) DECREASES BILIARY SENESCENCE AND LIVER FIBROSIS THROUGH RESTORATION OF THE CIRCADIAN RHYTHM. Gastroenterology. 158: S-1309. DOI: 10.1016/S0016-5085(20)33935-4  0.574
2020 Yang Z, Kusumanchi P, Zhang T, han s, Jiang Y, Meng F, Francis HL, Alpini G, Ross RA, Liangpunsakul S. 917 A NOVEL MECHANISM OF SMALL HETERODIMER PARTNER, CLOCK MACHINERY REV-ERBα, AND CYTOCHROME P450 4A IN THE PATHOGENESIS OF ALCOHOL-INDUCED LIVER INJURY Gastroenterology. 158: S-1296-S-1297. DOI: 10.1016/S0016-5085(20)33903-2  0.346
2020 Kyritsi K, Zhou T, Kennedy L, Meadows V, Wu C, Wu N, Meng F, Kundu D, Chen A, Ekser B, Glaser SS, Alpini G, Francis HL. 693 CROSSTALK SIGNALING BETWEEN MAST CELLS, HISTAMINE AND STIMULATOR OF INTERFERON GENE (STING/TMEM173) PROMOTES CHOLANGIOCARCINOMA (CCA) TUMORIGENESIS Gastroenterology. 158: S-1287. DOI: 10.1016/S0016-5085(20)33881-6  0.49
2020 Kennedy L, Chen L, Wu N, Ceci L, Meadows V, Ekser B, Liangpunsakul S, Glaser SS, Francis HL, Alpini G. 689 COMBINED URSODEOXYCHOLIC ACID (UDCA) AND SECRETIN RECEPTOR ANTAGONIST (SEC 5-27) TREATMENT DECREASES LIVER DAMAGE BY COORDINATELY DECREASING BOTH SECRETIN (SCT) AND FXR/FGF SIGNALING IN PRIMARY SCLEROSING CHOLANGITIS (PSC). Gastroenterology. 158: S-1285. DOI: 10.1016/S0016-5085(20)33877-4  0.567
2020 Wu N, Kennedy L, Zhou T, Kyritsi K, Chen L, Ceci L, Grumbles K, Francis HL, Meadows V, Meng F, Ekser B, O'Brien A, Rivosecchi-Fulton J, Onori P, Gaudio E, ... ... Alpini G, et al. 454 LONG-TERM ADMINISTRATION OF THE SECRETIN RECEPTOR ANTAGONIST, SCT 5-27, INHIBITS BILIARY SENESCENCE AND LIVER FIBROSIS OF PRIMARY SCLEROSING CHOLANGITIS (PSC) IN THE MDR2-/- MOUSE MODEL. Gastroenterology. 158: S-1277. DOI: 10.1016/S0016-5085(20)33855-5  0.566
2020 Chen L, Wu N, Glaser SS, Ceci L, Liangpunsakul S, Yang Z, Kennedy L, Meng F, Meadows V, Kundu D, Alpini G, Francis HL. 319 TREATMENT WITH MELATONIN OR DARK THERAPY DECREASES MAST CELL (MC) ACTIVATION BY DOWNREGULATION OF MIR-200B-DEPENDENT HISTAMINE (HA) SIGNALING IN MDR2-/- MICE: A NOVEL SCENARIO FOR PSC MANAGEMENT Gastroenterology. 158: S-1266. DOI: 10.1016/S0016-5085(20)33821-X  0.486
2020 Zhou T, Wu N, Chen L, Ceci L, O'Brien A, White T, Kennedy L, Wu C, Meng F, Francis HL, Alpini G, Glaser SS. 216 MELATONIN MODULATES STIMULATOR OF INTERFERON GENES (STING) ACTIVATION IN THE MDR2-/-MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC) Gastroenterology. 158: S-1262. DOI: 10.1016/S0016-5085(20)33811-7  0.477
2020 Sato K, Meng F, Kennedy L, Slevin E, Grumbles K, Francis HL, Glaser SS, Alpini G. 214 CHOLANGIOCYTE-DERIVED EXTRACELLULAR VESICLES REGULATE FIBROGENESIS AND EPITHELIAL-MESENCHYMAL TRANSITION OF HEPATIC STELLATE CELLS DURING CHOLESTATIC LIVER INJURY. Gastroenterology. 158: S-1262. DOI: 10.1016/S0016-5085(20)33809-9  0.583
2019 Zhou Y, Peng H, Xu H, Li J, Golovko M, Cheng H, Lynch EC, Liu L, McCauley N, Kennedy L, Alpini G, Zhang KK, Xie L. Maternal diet intervention before pregnancy primes offspring lipid metabolism in liver. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31748681 DOI: 10.1038/S41374-019-0344-4  0.301
2019 O'Brien A, Zhou T, Tan C, Alpini G, Glaser S. Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models. Cancers. 11. PMID 31731549 DOI: 10.3390/Cancers11111652  0.536
2019 Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, ... ... Alpini G, et al. Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2 mouse model of primary sclerosing cholangitis (PSC). Ebiomedicine. PMID 31522982 DOI: 10.1016/J.Ebiom.2019.09.013  0.568
2019 Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2 mice. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165557. PMID 31521820 DOI: 10.1016/J.Bbadis.2019.165557  0.428
2019 Baiocchi L, Zhou T, Liangpunsakul S, Ilaria L, Milana M, Meng F, Kennedy L, Kusumanchi P, Yang Z, Ceci L, Glaser S, Francis H, Alpini GD. Possible application of melatonin treatment in human diseases of the biliary tract. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31509434 DOI: 10.1152/Ajpgi.00110.2019  0.558
2019 Raggi C, Fiaccadori K, Pastore M, Correnti M, Piombanti B, Forti E, Navari N, Abbadessa G, Hall T, Destro A, Di Tommaso L, Roncalli M, Meng F, Glaser S, Rovida E, ... ... Alpini G, et al. Antitumor Activity of a Novel Fibroblast Growth Factor Receptor (FGFR) Inhibitor for Intrahepatic Cholangiocarcinoma. The American Journal of Pathology. PMID 31351075 DOI: 10.1016/J.Ajpath.2019.06.007  0.536
2019 Kyritsi K, Chen L, O'Brien A, Francis H, Hein TW, Venter J, Wu N, Ceci L, Zhou T, Zawieja D, Gashev AA, Meng F, Invernizzi P, Fabris L, Wu C, ... ... Alpini G, et al. Modulation of the TPH1/MAO-A/5HT/5HTR2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis. Hepatology (Baltimore, Md.). PMID 31344280 DOI: 10.1002/Hep.30880  0.534
2019 Kennedy L, Francis H, Alpini G. Fructose Promotion of Intestinal and Liver Injury: A Sugar by Any Other Name That Isn't So Sweet. Hepatology (Baltimore, Md.). PMID 31273795 DOI: 10.1002/Hep.30843  0.386
2019 Kennedy L, Francis H, Invernizzi P, Venter J, Wu N, Carbone M, Gershwin ME, Bernuzzi F, Franchitto A, Alvaro D, Marzioni M, Onori P, Gaudio E, Sybenga A, Fabris L, ... ... Alpini G, et al. Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early-stage primary biliary cholangitis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802606R. PMID 31251081 DOI: 10.1096/Fj.201802606R  0.578
2019 Sato K, Kennedy L, Liangpunsakul S, Kusumanchi P, Yang Z, Meng F, Glaser S, Francis H, Alpini G. Intercellular Communication between Hepatic Cells in Liver Diseases. International Journal of Molecular Sciences. 20. PMID 31052525 DOI: 10.3390/Ijms20092180  0.576
2019 Alpini G. Sphingosine lipid signaling in alcoholic liver injury. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 31031176 DOI: 10.1016/J.Dld.2019.04.002  0.348
2019 Baiocchi L, Zhou T, Liangpunsakul S, Lenci I, Santopaolo F, Meng F, Kennedy L, Glaser S, Francis H, Alpini G. Dual Role of Bile Acids on the Biliary Epithelium: Friend or Foe? International Journal of Molecular Sciences. 20. PMID 31014010 DOI: 10.3390/Ijms20081869  0.556
2019 Sato K, Glaser S, Kennedy L, Liangpunsakul S, Meng F, Francis H, Alpini G. Preclinical insights into cholangiopathies: disease modeling and emerging therapeutic targets. Expert Opinion On Therapeutic Targets. 1-12. PMID 30990740 DOI: 10.1080/14728222.2019.1608950  0.516
2019 Navas MC, Glaser S, Dhruv H, Celinski S, Alpini G, Meng F. Hepatitis C virus infection and cholangiocarcinoma: An insight into epidemiological evidences and hypothetical mechanisms of oncogenesis. The American Journal of Pathology. PMID 30953604 DOI: 10.1016/J.Ajpath.2019.01.018  0.482
2019 Chen L, Zhou T, Wu N, O'Brien A, Venter J, Ceci L, Kyritsi K, Onori P, Gaudio E, Sybenga A, Xie L, Wu C, Fabris L, Invernizzi P, Zawieja D, ... ... Alpini G, et al. Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30890428 DOI: 10.1016/J.Bbadis.2019.03.002  0.59
2019 Alpini G, Tariq R, Singal AK. FXR deficiency and alcoholic liver disease: Tissue is the issue. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 30826275 DOI: 10.1016/J.Dld.2019.01.014  0.338
2019 McDaniel K, Wu N, Zhou T, Huang L, Sato K, Venter J, Ceci L, Chen D, Ramos-Lorenzo S, Invernizzi P, Bernuzzi F, Wu C, Francis H, Glaser S, Alpini G, et al. Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 knockout mice via let-7 microRNA. Hepatology (Baltimore, Md.). PMID 30723922 DOI: 10.1002/Hep.30542  0.568
2019 Wan Y, Ceci L, Wu N, Zhou T, Chen L, Venter J, Francis H, Bernuzzi F, Invernizzi P, Kyritsi K, Baker P, Huang Q, Wu C, Sybenga A, Alpini G, et al. Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30700848 DOI: 10.1038/S41374-018-0178-5  0.583
2019 Kennedy L, Francis H, Alpini G. Hepatocyte-specific and extra-hepatocyte actions of Perilipin-2 during fatty liver disease: Benefits of being extra. The Journal of Physiology. PMID 30656685 DOI: 10.1113/Jp277539  0.409
2019 Rath S, Peng S, Hartman L, Reid G, Dhruv H, Glaser S, Meng F, Alpini G, Celinski S. Abstract 1072: Development and characterization of patient derived xenograft (PDX) avatars of human cholangiocarcinoma Cancer Research. 79: 1072-1072. DOI: 10.1158/1538-7445.Sabcs18-1072  0.449
2019 Kennedy L, Francis HL, Wu N, Venter J, Fabris L, Gershwin E, Invernizzi P, Meng F, Zawieja DC, Glaser S, Alpini G. Mo1470 – Secretin/Secretin Receptor Signaling Modulates Biliary Immunobiology and Subsequent T Cell Migration in Early Stage Primary Biliary Cholangitis (PBC) Gastroenterology. 156: S-1318. DOI: 10.1016/S0016-5085(19)40311-9  0.496
2019 Wu N, McDaniel KM, Zhou T, Celinski S, Huang L, Dhruv H, Francis HL, Glaser S, Alpini G, Meng F. Mo1436 – Regulation of Chemoresistance by Microrna-17-92 Cluster in Patient-Derived Cholangiocarcinoma Xenograft Tumors Gastroenterology. 156: S-1306. DOI: 10.1016/S0016-5085(19)40277-1  0.449
2019 Glaser S, Chen L, O'Brien A, Cromer W, Alpini G, Zawieja DC. Mo1431 – Inflammatory Bowel Disease (IBD) Induces Biliary Damage and Liver Fibrosis in an IBD Rat Model Gastroenterology. 156: S-1305-S-1306. DOI: 10.1016/S0016-5085(19)40274-6  0.559
2019 Sato K, Venter J, Meng F, Kennedy L, Francis HL, Glaser S, Alpini G. Mo1430 – The Proliferative Activity of Cholangiocytes is Regulated by Micrornas Carried in Extracellular Vesicles Secreted from Other Cholangiocytes Gastroenterology. 156: S-1305. DOI: 10.1016/S0016-5085(19)40273-4  0.492
2019 Sato K, Wu N, Zhou T, Glaser S, Francis HL, Alpini G, Meng F. Mo1429 – Microrna Induced Glycolysis Metabolism is Essential to the Activation of Inflammatory Macrophages in Cholestatic Liver Injury Gastroenterology. 156: S-1305. DOI: 10.1016/S0016-5085(19)40272-2  0.544
2019 Ceci L, Wu N, Chen L, O'Brien A, Zhou T, Kennedy L, Kyritsi K, Gaudio E, Venter J, Meng F, Onori P, Francis HL, Glaser S, Alpini G. Mo1428 – Role of the Aanat/Melatonin/Mt1/Mt2/Per-1 Axis in the Regulation of Biliary Damage and Liver Fibrosis in Cholestatic Mice Gastroenterology. 156: S-1305. DOI: 10.1016/S0016-5085(19)40271-0  0.569
2019 Han Y, Cheplick F, Wu N, Zhou T, Kennedy L, Francis HL, Meng F, Chen L, Glaser S, Alpini G. Su1545 – Differential Dna Methylation Status in Core Clock Genes Leads to Altered Circadian Rhythm in High-Fat Diet Fed Mice Gastroenterology. 156: S-1293-S-1294. DOI: 10.1016/S0016-5085(19)40239-4  0.444
2019 Zhou T, Wu N, McDaniel KM, Glaser S, Francis HL, Alpini G, Meng F. Su1023 – Regulation of Endothelial Progenitor Cell Function by Microrna in Cholestatic Liver Injury Gastroenterology. 156: S-1267. DOI: 10.1016/S0016-5085(19)40168-6  0.571
2019 Gashev A, Gasheva O, Alpini G, Zawieja DC, Glaser S. Sa1521 – Dysfunction of Collecting Liver Lymphatics During the Progression of Extrahepatic Cholestasis Gastroenterology. 156: S-1232. DOI: 10.1016/S0016-5085(19)40071-1  0.574
2019 Zhou T, Chen L, Wu N, Kyritsi K, Venter J, Ceci L, Meng F, Kennedy L, Francis HL, Zawieja DC, Gashev A, Alpini G, Wu C, Glaser S. Sa1520 – Knockdown of Stimulator of Interferon Genes (STING) Reduces Biliary Senescence and Liver Inflammation and Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis (PSC) Gastroenterology. 156: S-1231. DOI: 10.1016/S0016-5085(19)40070-X  0.574
2019 Kyritsi K, Chen L, Venter J, Zhou T, Ceci L, Kennedy L, Guillot A, Francis HL, Gao B, Wu N, White T, Liangpunsakul S, Meng F, Alpini G, Glas S. Sa1510 – Increased Serotonin (5HT) Biliary Synthesis Due to Enhanced Expression of Tryptophan Hydroxylase1 (TPH1) and Reduced Monoamine-Oxidase-A (MAO-A) Expression is Couple with Alcohol-Induced Liver Injury (ALI) Gastroenterology. 156: S-1228-S-1229. DOI: 10.1016/S0016-5085(19)40060-7  0.339
2019 Kennedy L, Demieville J, Hargrove L, Meadows V, Meng F, Glaser S, Tolefree JA, Reinhart E, Virani S, Liangpunsakul S, Alpini G, Francis HL. Sa1508 – Biliary L-Histidine Decarboxylase (HDC) Activity Induces Ductular Reaction (DR) and Subsequent Liver Fibrosis During Alcoholic Liver Injury (ALI) Gastroenterology. 156: S-1228. DOI: 10.1016/S0016-5085(19)40058-9  0.568
2019 Wu N, Guillot A, Zhou T, Venter J, Kennedy L, Kyritsi K, Ceci L, Chen L, Francis HL, White T, Gao B, Liangpunsakul S, Zawieja DC, Alpini G, Glaser S, et al. Sa1502 – Knockout (KO) of the Melatonin Receptor, Mt2, Enhances Alcohol-Induced Ductular Reaction (DR), Biliary Senescence and Hepatic Fibrosis During Alcoholic Liver Disease (ALD) Gastroenterology. 156: S-1226. DOI: 10.1016/S0016-5085(19)40052-8  0.545
2019 Sato K, Venter J, Kennedy L, Francis HL, Meng F, Glaser S, Alpini G. 772 – Extracellular Vesicles Isolated from Cholangiocytes Lacking the Secretin/Secretin Receptor Axis Attenuate Liver Fibrosis Via Cargo Micrornas in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis Gastroenterology. 156: S-1215-S-1216. DOI: 10.1016/S0016-5085(19)40023-1  0.579
2019 Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Glaser S, Alpini G, Francis HL. 492 – Mast Cell Regulation of Biliary Bile Acid Transporter, Asbt Via Nuclear Bile Acid Receptor Fxr/Histamine Signaling During Cholestatic Liver Injury Gastroenterology. 156: S-1199. DOI: 10.1016/S0016-5085(19)39977-9  0.569
2019 Sato K, Meng F, Fava G, Glaser S, Alpini G. Functional roles of gut bacteria imbalance in cholangiopathies Liver Research. 3: 40-45. DOI: 10.1016/J.Livres.2018.11.001  0.548
2018 Virani S, Akers A, Stephenson K, Smith S, Kennedy L, Alpini G, Francis H. Comprehensive Review of Molecular Mechanisms during Cholestatic Liver Injury and Cholangiocarcinoma. Journal of Liver. 7. PMID 30613437 DOI: 10.4172/2167-0889.1000231  0.406
2018 Newberry EP, Xie Y, Lodeiro C, Solis R, Moritz W, Kennedy S, Barron L, Onufer E, Alpini G, Zhou T, Blaner WS, Chen A, Davidson NO. Hepatocyte and stellate cell deletion of liver fatty acid binding protein reveals distinct roles in fibrogenic injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801976R. PMID 30576225 DOI: 10.1096/Fj.201801976R  0.368
2018 Pei Y, Li H, Cai Y, Zhou J, Luo X, Ma L, McDaniel K, Zeng T, Chen Y, Qian X, Huo Y, Glaser S, Meng F, Alpini G, Chen L, et al. Regulation of adipose tissue inflammation by adenosine 2A receptor in obese mice. The Journal of Endocrinology. 239: 365-376. PMID 30400017 DOI: 10.1530/Joe-18-0169  0.484
2018 Luo X, Li H, Ma L, Zhou J, Guo X, Woo SL, Pei Y, Knight LR, Deveau M, Chen Y, Qian X, Xiao X, Li Q, Chen X, Huo Y, ... ... Alpini G, et al. Expression of STING Is Increased in Liver Tissues from Patients With NAFLD and Promotes Macrophage-mediated Hepatic Inflammation and Fibrosis in Mice. Gastroenterology. PMID 30213555 DOI: 10.1053/J.Gastro.2018.09.010  0.587
2018 Meng F, Kennedy L, Hargrove L, Demieville J, Jones H, Madeka T, Karstens A, Chappell K, Alpini G, Sybenga A, Invernizzi P, Bernuzzi F, DeMorrow S, Francis H. Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2 mice and human primary sclerosing cholangitis. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30143751 DOI: 10.1038/S41374-018-0101-0  0.42
2018 Lewis PL, Su J, Yan M, Meng F, Glaser SS, Alpini GD, Green RM, Sosa-Pineda B, Shah RN. Complex bile duct network formation within liver decellularized extracellular matrix hydrogels. Scientific Reports. 8: 12220. PMID 30111800 DOI: 10.1038/S41598-018-30433-6  0.509
2018 Sato K, Marzioni M, Meng F, Francis H, Glaser S, Alpini G. Ductular reaction in liver diseases: pathological mechanisms and translational significances. Hepatology (Baltimore, Md.). PMID 30070383 DOI: 10.1002/Hep.30150  0.614
2018 Wu N, Meng F, Zhou T, Venter J, Giang TK, Kyritsi K, Wu C, Alvaro D, Onori P, Mancinelli R, Gaudio E, Francis H, Alpini G, Glaser S, Franchitto A. The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor (TGF)-β1-Mediated Biliary Senescence. The American Journal of Pathology. PMID 30036520 DOI: 10.1016/J.Ajpath.2018.06.015  0.609
2018 Sato K, Meng F, Venter J, Giang T, Glaser S, Alpini G. Author Correction: The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles. Scientific Reports. 8: 11238. PMID 30026581 DOI: 10.1038/S41598-018-29609-X  0.449
2018 Zhou T, Wu N, Meng F, Venter J, Giang TK, Francis H, Kyritsi K, Wu C, Franchitto A, Alvaro D, Marzioni M, Onori P, Mancinelli R, Gaudio E, Glaser S, ... Alpini G, et al. Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2 mice by diminishing senescence of cholangiocytes. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29977037 DOI: 10.1038/S41374-018-0093-9  0.577
2018 Wu N, McDaniel K, Zhou T, Ramos-Lorenzo S, Wu C, Huang L, Chen D, Annable T, Francis H, Glaser S, Alpini G, Meng F. Knockout of microRNA-21 attenuates alcoholic hepatitis through VHL/NF-κB signaling pathway in hepatic stellate cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29848019 DOI: 10.1152/Ajpgi.00111.2018  0.57
2018 Ehrlich L, Scrushy M, Meng F, Lairmore TC, Alpini G, Glaser S. Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease. Clinics and Research in Hepatology and Gastroenterology. PMID 29678444 DOI: 10.1016/J.Clinre.2018.03.009  0.603
2018 Ehrlich L, O'Brien A, Hall C, White T, Chen L, Wu N, Venter J, Scrushy M, Mubarak M, Meng F, Dostal D, Wu C, Lairmore TC, Alpini G, Glaser S. α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile-Duct Ligated Mice. Gene Expression. PMID 29580318 DOI: 10.3727/105221618X15216453076707  0.57
2018 Mancinelli R, Olivero F, Carpino G, Overi D, Rosa L, Lepanto MS, Cutone A, Franchitto A, Alpini G, Onori P, Valenti P, Gaudio E. Role of lactoferrin and its receptors on biliary epithelium. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 29550924 DOI: 10.1007/S10534-018-0094-6  0.384
2018 Cai Y, Li H, Liu M, Pei Y, Zheng J, Zhou J, Luo X, Huang W, Ma L, Yang Q, Guo S, Xiao X, Li Q, Zeng T, Meng F, ... ... Alpini G, et al. Disruption of Adenosine 2A Receptor Exacerbates NAFLD through Increasing Inflammatory Responses and SREBP1c Activity. Hepatology (Baltimore, Md.). PMID 29315766 DOI: 10.1002/Hep.29777  0.536
2018 Chen L, White T, Venter J, Ehrlich L, O'Brien A, Nguyen AV, Wu N, Kyritsi K, Han Y, Huang Q, Meng F, Alpini G, Zhou T, Glaser S. Mo1377 - Pinealectomy Exacerbates Biliary Proliferation and Senescence and Liver Fibrosis During Rat Cholestatic Liver Through Decreased Biliary Melatonin Synthesis Gastroenterology. 154: S-1187. DOI: 10.1016/S0016-5085(18)33925-8  0.602
2018 Sato K, Kennedy L, Giang T, Zhou T, Ramos-Lorenzo S, Francis HL, Glaser S, Alpini G, Meng F. Mo1376 - Therapeutic Effects of Microrna-21 Depletion on Inflammatory Response in Liver Macrophages During Cholestatic Liver Injury Gastroenterology. 154: S-1186-S-1187. DOI: 10.1016/S0016-5085(18)33924-6  0.576
2018 Zhou T, Kyritsi K, Wu N, Venter J, Francis HL, Meng F, Chen L, Giang T, White T, Alpini G, Glaser S. Mo1373 - Knockout of Secretin/Secretin Receptor Axis (SCT/SR) Reduces Liver Fibrosis by Angiogenesis-Dependent Reduced Senescence of Cholangiocytes but Increased Senescence of Hepatic Stellate Cells (HSCS) in the MDR2 −/− Mouse Model of Primary Sclerosing Cholangitis (PSC) Gastroenterology. 154: S-1185. DOI: 10.1016/S0016-5085(18)33921-0  0.583
2018 Wu N, Zhou T, Venter J, Wu C, Onori P, Alvaro D, Franchitto A, Meng F, Giang T, Gaudio E, Francis HL, Kyritsi K, Alpini G, Glaser S. Mo1372 - Loss of the Biliary Secretin/Secretin Receptor (SCT/SR) Axis Decreases Liver Fibrosis by Enhanced Senescence of Hepatic Stellate Cells (HSCS) Through Decreased Biliary Secretion of TGFβ1 Gastroenterology. 154: S-1185. DOI: 10.1016/S0016-5085(18)33920-9  0.605
2018 Wu N, Sato K, Kennedy L, Zhou T, McDaniel KM, Ramos-Lorenzo S, Francis HL, Glaser S, Alpini G, Meng F. Sa1466 - Knockout of Microrna-21 Attenuates Alcoholic Hepatitis Through VHL/NF-KB Signaling Pathway Gastroenterology. 154: S-1122. DOI: 10.1016/S0016-5085(18)33733-8  0.501
2018 McDaniel K, Guillot A, Wu N, Kyritsi K, Ramos-Lorenzo S, Giang T, Francis HL, Venter J, Glaser S, Meng F, Gao B, Alpini G. Sa1453 - Secretin Knockout Reduces Liver Damage in Alcoholic Liver Disease Gastroenterology. 154: S-1118. DOI: 10.1016/S0016-5085(18)33720-X  0.566
2018 Kennedy L, Wu N, Francis HL, Venter J, Meng F, Mancinelli R, Bennett M, Giang T, Invernizzi P, Bernuzzi F, Onori P, Franchitto A, Kyritsi K, Zhou T, Alvaro D, ... ... Alpini G, et al. 557 - Melatonin and Dark Therapy Reduce Biliary Damage, Liver Fibrosis and Angiogenesis in a Murine Model of Early Stage Primary Biliary Cholangitis (PBC) Gastroenterology. 154: S-1096-S-1097. DOI: 10.1016/S0016-5085(18)33651-5  0.55
2018 Giang T, Zhou T, Venter J, White T, Wu N, Meng F, Onori P, Gaudio E, Franchitto A, Bennett M, Alpini G, Glaser S. 510 - Knockout of the Substance P/Neurokinin-1 Receptor (SP/NK-1R) Axis Reduces Liver Fibrosis and Biliary Damage in the Murine Model of Primary Sclerosing Cholangitis (PSC) Gastroenterology. 154: S-1095. DOI: 10.1016/S0016-5085(18)33644-8  0.541
2018 Keisaku S, Venter J, Giang T, Francis HL, Glaser S, Alpini G, Meng F. 509 - Therapeutic Effects of Extracellular Vesicles Isolated from Cholangiocytes Lacking the Secretin/Secretin Receptor (SCT/SRT) Axis on a Mouse Model of Primary Sclerosing Cholangitis Gastroenterology. 154: S-1095. DOI: 10.1016/S0016-5085(18)33643-6  0.489
2018 Zhou T, McDaniel KM, Ramos-Lorenzo S, Wu N, Francis HL, Glaser S, Alpini G, Meng F. 245 - Liver Specific Deletion of Microrna-34A Alleviates Cellular Senescence and Liver Fibrosis During Experimental Cholestasis Gastroenterology. 154: S-1079. DOI: 10.1016/S0016-5085(18)33596-0  0.574
2018 Lewis PL, Su J, Venter J, Meng F, Glaser S, Green RM, Alpini G, Sosa-Pineda B, Shah RN. 243 - In Vitro Formation of Three-Dimensional Biliary Trees Within Decellularized Liver Extracellular Matrix Hydrogels Gastroenterology. 154: S-1078-S-1079. DOI: 10.1016/S0016-5085(18)33594-7  0.533
2017 Francis H, Kennedy L, Alpini G. Dual ablation of β- and γ-catenin: Critical regulators of junctions and their functions. Hepatology (Baltimore, Md.). PMID 29272046 DOI: 10.1002/Hep.29761  0.329
2017 Kennedy L, Hargrove L, Demieville J, Bailey J, Dar W, Polireddy K, Chen Q, Nevah Rubin MI, Sybenga A, DeMorrow S, Meng F, Stockton L, Alpini G, Francis H. Knockout of l-Histidine Decarboxylase (HDC-/-) Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling. The American Journal of Pathology. PMID 29248461 DOI: 10.1016/J.Ajpath.2017.11.016  0.39
2017 Raggi C, Gammella E, Correnti M, Buratti P, Forti E, Andersen JB, Alpini G, Glaser S, Alvaro D, Invernizzi P, Cairo G, Recalcati S. Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells. Scientific Reports. 7: 17667. PMID 29247214 DOI: 10.1038/S41598-017-17804-1  0.503
2017 Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, ... Alpini G, et al. Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury. The American Journal of Pathology. PMID 29128099 DOI: 10.1016/J.Ajpath.2017.08.027  0.554
2017 Stephenson K, Kennedy L, Hargrove L, Demieville J, Thomson J, Alpini G, Francis H. Updates on Dietary Models of Non-Alcoholic Fatty Liver Disease: Current Studies and Insights. Gene Expression. PMID 29096730 DOI: 10.3727/105221617X15093707969658  0.337
2017 Kennedy I, Francis H, Meng F, Glaser S, Alpini G. Diagnostic and therapeutic potentials of microRNAs in cholangiopathies. Liver Research. 1: 34-41. PMID 29085701 DOI: 10.1016/J.Livres.2017.03.003  0.546
2017 Sato K, Meng F, Venter J, Giang T, Glaser S, Alpini G. The role of the secretin/secretin receptor axis in inflammatory cholangiocyte communication via extracellular vesicles. Scientific Reports. 7: 11183. PMID 28894209 DOI: 10.1038/S41598-017-10694-3  0.508
2017 McMillin M, DeMorrow S, Glaser S, Venter J, Kyritsi K, Zhou T, Grant S, Giang T, Greene JF, Wu N, Jefferson B, Meng F, Alpini G. Melatonin inhibits hypothalamic gonandotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00421.2016. PMID 28751425 DOI: 10.1152/Ajpgi.00421.2016  0.59
2017 Guo X, Shu C, Li H, Pei Y, Woo SL, Zheng J, Liu M, Xu H, Botchlett R, Guo T, Cai Y, Gao X, Zhou J, Chen L, Li Q, ... ... Alpini G, et al. Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation. Scientific Reports. 7: 6355. PMID 28743914 DOI: 10.1038/S41598-017-05884-Y  0.328
2017 Sato K, Meng F, Giang T, Glaser S, Alpini G. Mechanisms of cholangiocyte responses to injury. Biochimica Et Biophysica Acta. PMID 28648950 DOI: 10.1016/J.Bbadis.2017.06.017  0.62
2017 Wu N, Meng F, Zhou T, Han Y, Kennedy L, Venter J, Francis H, DeMorrow S, Onori P, Invernizzi P, Bernuzzi F, Mancinelli R, Gaudio E, Franchitto A, Glaser S, ... Alpini G, et al. Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28634212 DOI: 10.1096/Fj.201700097R  0.562
2017 Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S. Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2(-/-) mice. The Journal of Surgical Research. PMID 28602220 DOI: 10.1016/J.Jss.2017.05.020  0.599
2017 Wu N, Nguyen Q, Wan Y, Zhou T, Venter J, Frampton GA, DeMorrow S, Pan D, Meng F, Glaser S, Alpini G, Bai H. The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 28581486 DOI: 10.1038/Labinvest.2017.29  0.513
2017 McDaniel K, Huang L, Sato K, Wu N, Annable T, Zhou T, Ramos-Lorenzo S, Wan Y, Huang Q, Francis H, Glaser S, Tsukamoto H, Alpini G, Meng F. The let-7/lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury. The Journal of Biological Chemistry. PMID 28536261 DOI: 10.1074/Jbc.M116.773291  0.591
2017 Kyritsi K, Meng F, Zhou T, Wu N, Venter J, Francis H, Kennedy L, Onori P, Franchitto A, Bernuzzi F, Invernizzi P, McDaniel K, Mancinelli R, Alvaro D, Gaudio E, ... Alpini G, et al. Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. The American Journal of Pathology. PMID 28502477 DOI: 10.1016/J.Ajpath.2017.03.013  0.572
2017 Ehrlich L, Hall C, Meng F, Lairmore T, Alpini G, Glaser S. A Review of the Scaffold Protein Menin and its Role in Hepatobiliary Pathology. Gene Expression. PMID 28485270 DOI: 10.3727/105221617X695744  0.519
2017 Martínez AK, Jensen K, Hall C, O'Brien A, Ehrlich L, White T, Meng F, Zhou T, Greene J, Bernuzzi F, Invernizzi P, Dostal DE, Lairmore T, Alpini G, Glaser S. Nicotine Promotes Cholangiocarcinoma Growth in Xenograft Mice. The American Journal of Pathology. PMID 28315314 DOI: 10.1016/J.Ajpath.2017.01.011  0.513
2017 Wan Y, Meng F, Wu N, Zhou T, Venter J, Francis H, Kennedy L, Glaser T, Bernuzzi F, Invernizzi P, Glaser S, Huang Q, Alpini G. Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells. Hepatology (Baltimore, Md.). PMID 28256736 DOI: 10.1002/Hep.29138  0.563
2017 Ehrlich L, Hall C, Venter J, Dostal D, Bernuzzi F, Invernizzi P, Meng F, Trzeciakowski JP, Zhou T, Standeford H, Alpini G, Lairmore TC, Glaser S. miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation. The American Journal of Pathology. PMID 28087162 DOI: 10.1016/J.Ajpath.2016.10.021  0.503
2017 Mancinelli R, Onori P, Franchitto A, Francis H, Venter J, Alpini G, Gaudio E. Knockdown of hepatic GnRH reduces liver fibrosis in a mouse model of PSC Italian Journal of Anatomy and Embryology. 122: 131. DOI: 10.13128/Ijae-21523  0.439
2017 Wu N, Zhou T, Venter J, Sato K, Kennedy L, Alvaro D, Francis HL, Onori P, Gaudio E, Meng F, Alpini G, Glaser S. Knockout of the Secretin Receptor (SR) in Experimental Primary Sclerosing Cholangitis Reduces Biliary Hyperplasia and Liver Fibrois through Decreased Expression of Epithelial-Mesenchymal Transitions (EMT) Traits and Cellular Senescence in Cholangiocytes Gastroenterology. 152: S1155. DOI: 10.1016/S0016-5085(17)33870-2  0.581
2017 Wan Y, McDaniel KM, Wu N, Ramos-Lorenzo S, Zhou T, Sato K, Venter J, Francis HL, Glaser S, Tsukamoto H, Alpini G, Meng F. Characterization of Endothelial Dysfunction in Microrna-34A Knockout Mice with Alcoholic Liver Injury Gastroenterology. 152: S1111. DOI: 10.1016/S0016-5085(17)33741-1  0.528
2017 Kyritsi K, Meng F, Wu N, Venter J, Zhou T, Francis HL, Kennedy L, Gang T, Sato K, Alpini G, Glaser S. Inhibition of the Gonadotropin Releasing Hormone (GNRH)/GNRHR1 Axis with Cetrorelix Reduces Hepatic Fibrosis in MDR2 -/- Mice Gastroenterology. 152: S1073. DOI: 10.1016/S0016-5085(17)33624-7  0.521
2017 Sato K, Meng F, Venter J, Wu N, Zhou T, McDaniel K, Glaser S, Alpini G. The Secretin/Secretin Receptor Axis is Required for Inflammatory Cell-Cell Communication Via Extracellular Vesicles Between Cholangiocytes Treated with Lipopolysaccharide Gastroenterology. 152: S1067. DOI: 10.1016/S0016-5085(17)33603-X  0.486
2017 McDaniel K, Zhou T, Ramos-Lorenzo S, Venter J, Sato K, Francis HL, Wu N, Glaser S, Kyritsi K, Alpini G, Meng F. Stem Cell Derived Extracellular Vesicles Inhibits Liver Inflammation and Fibrosis in a Mouse Model of Primary Sclerosing Cholangitis Gastroenterology. 152: S1066-S1067. DOI: 10.1016/S0016-5085(17)33602-8  0.572
2017 Sato K, Kennedy L, Zhou T, McDaniel KM, Ramos-Lorenzo S, Wan Y, Venter J, Francis HL, Glaser S, Alpini G, Meng F. Depletion of Microrna-21 Reduces Infiltration of Macrophages and Neutrophils in the Liver and Attenuates Inflammatory Cytokine Production in Liver Macrophages During Experimental Cholestatic Liver Injury Gastroenterology. 152: S1064. DOI: 10.1016/S0016-5085(17)33593-X  0.569
2017 Kennedy L, Francis HL, Venter J, Hargrove L, Invernizzi P, Bernuzzi F, Alvaro D, Wu N, Onori P, Gaudio E, Franchitto A, Meng F, Glaser S, Alpini G. Secretin-Stimulation of Bicarbonate Secretion Reduces Biliary Damage and Liver Fibrosis in a Model of Primary Biliary Cholangitis (PBC) Gastroenterology. 152: S1060. DOI: 10.1016/S0016-5085(17)33579-5  0.58
2016 Hall C, Ehrlich L, Venter J, O'Brien A, White T, Zhou T, Dang T, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Lairmore T, Glaser S. Inhibition of the Apelin/Apelin Receptor Axis Decreases Cholangiocarcinoma Growth. Cancer Letters. PMID 27894959 DOI: 10.1016/J.Canlet.2016.11.025  0.502
2016 Kennedy LL, Meng F, Venter JK, Zhou T, Karstens WA, Hargrove LA, Wu N, Kyritsi K, Greene J, Invernizzi P, Bernuzzi F, Glaser SS, Francis HL, Alpini G. Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 27775690 DOI: 10.1038/Labinvest.2016.112  0.545
2016 McDaniel K, Meng F, Wu N, Sato K, Venter J, Bernuzzi F, Invernizzi P, Zhou T, Kyritsi K, Wan Y, Huang Q, Onori P, Francis H, Gaudio E, Glaser S, ... Alpini G, et al. Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury. Hepatology (Baltimore, Md.). PMID 27639079 DOI: 10.1002/Hep.28831  0.572
2016 Raggi C, Correnti M, Sica A, Andersen JB, Cardinale V, Alvaro D, Chiorino G, Forti E, Glaser S, Alpini G, Destro A, Sozio F, Di Tommaso L, Roncalli M, Banales JM, et al. Cholangiocarcinoma Stem-like Cells Shapes Tumor-initiating Niche by Regulating Associated Macrophages. Journal of Hepatology. PMID 27593106 DOI: 10.1016/J.Jhep.2016.08.012  0.463
2016 Mancinelli R, Franchitto A, Glaser S, Vetuschi A, Venter J, Sferra R, Pannarale L, Olivero F, Carpino G, Alpini G, Onori P, Gaudio E. Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 27571215 DOI: 10.1038/Labinvest.2016.93  0.632
2016 Sato K, Meng F, Glaser S, Alpini G. Corrigendum to "Exosomes in liver pathology". Journal of Hepatology. 65: 655. PMID 27538765 DOI: 10.1016/J.Jhep.2016.06.016  0.578
2016 Sato K, Hall C, Glaser S, Francis H, Meng F, Alpini G. Pathogenesis of Kupffer Cells in Cholestatic Liver Injury. The American Journal of Pathology. PMID 27452297 DOI: 10.1016/J.Ajpath.2016.06.003  0.614
2016 Hall C, Sato K, Wu N, Zhou T, Kyritsi T, Meng F, Glaser S, Alpini G. Regulators of Cholangiocyte Proliferation. Gene Expression. PMID 27412505 DOI: 10.3727/105221616X692568  0.565
2016 Jones H, Hargrove L, Kennedy L, Meng F, Graf-Eaton A, Owens J, Alpini G, Johnson C, Bernuzzi F, Demieville J, DeMorrow S, Invernizzi P, Francis H. Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2(-/-) mice. Hepatology (Baltimore, Md.). PMID 27351144 DOI: 10.1002/Hep.28704  0.46
2016 Carpino G, Nobili V, Renzi A, De Stefanis C, Stronati L, Franchitto A, Alisi A, Onori P, De Vito R, Alpini G, Gaudio E. Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway. Plos One. 11: e0157246. PMID 27310371 DOI: 10.1371/Journal.Pone.0157246  0.42
2016 Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, Liu Y, Wu N, Joseph NE, Wang TL, Zhang N, Pan D, Alpini G, Robinson DN, Anders RA. Yes-Associated Protein impacts adherens junction assembly through regulating actin cytoskeleton organization. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00027.2016. PMID 27229120 DOI: 10.1152/Ajpgi.00027.2016  0.42
2016 Krishnamurthy K, Glaser S, Alpini G, Cardounel AJ, Liu Z, Ilangovan G. Heat Shock Factor-1 Knockout Enhances Cholesterol 7α Hydroxylase (CYP7A1) and Multidrug Transporter (MDR1) Gene Expressions to Attenuate Atherosclerosis. Cardiovascular Research. PMID 27131506 DOI: 10.1093/Cvr/Cvw094  0.391
2016 Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G. The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion. Hepatology (Baltimore, Md.). PMID 27115285 DOI: 10.1002/Hep.28622  0.586
2016 McDaniel K, Hall C, Sato K, Lairmore T, Marzioni M, Glaser S, Meng F, Alpini G. Lin28 and let-7: Roles and Regulation in Liver Diseases. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00080.2016. PMID 27012771 DOI: 10.1152/Ajpgi.00080.2016  0.589
2016 Sato K, Meng F, Glaser S, Alpini G. Exosomes in liver pathology. Journal of Hepatology. PMID 26988731 DOI: 10.1016/J.Jhep.2016.03.004  0.542
2016 Han Y, Meng F, Venter J, Wu N, Wan Y, Standeford H, Francis H, Meininger C, Greene J, Trzeciakowski JP, Ehrlich L, Glaser S, Alpini G. miR-34a-dependent overexpression of Per1 decreases cholangiocarcinoma growth. Journal of Hepatology. PMID 26923637 DOI: 10.1016/J.Jhep.2016.02.024  0.473
2016 Mancinelli R, Glaser S, Alpini G, Gaudio E. Role of the secretin/secretin receptor axis in the modulation of the liver fibrosis Italian Journal of Anatomy and Embryology. 121: 141. DOI: 10.13128/Ijae-21778  0.597
2016 Mancinelli R, Pannarale L, Glaser S, Alpini G, Onori P. Vasopressin induces cholangiocyte proliferation in experimental cholestasis and in Polycystic Liver Disease Italian Journal of Anatomy and Embryology. 121: 22. DOI: 10.13128/Ijae-21659  0.625
2016 Glaser S, Meng F, Wu N, Venter J, Kyritsi K, Alpini G. The secretin receptor antagonist (SCT 5‐27) reduces biliary hyperplasia and liver fibrosis in an animal model of primary sclerosing cholangitis The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.56.7  0.577
2016 Navas MC, Wu N, Venter J, Meng F, Onori P, Gaudio E, Glaser S, Alpini G. Tu1698 Modulation of Epithelial Mesenchymal Transition by miRNA125b in Cholestatic Bile Duct Ligated (BDL) Mice Gastroenterology. 150: S1166. DOI: 10.1016/S0016-5085(16)33939-7  0.485
2016 Wu N, Meng F, Venter J, Kyritsi K, Francis HL, Hall C, Zhou T, Kennedy L, Glaser S, Alpini G. Tu1694 Regulation of Cellular Senescence Associated Liver Fibrosis By Melatonin in Cholestatic Liver Injury Gastroenterology. 150: S1165. DOI: 10.1016/S0016-5085(16)33935-X  0.593
2016 Wan Y, Meng F, McDaniel K, Wu N, Venter J, Francis HL, Zhou T, Standeford H, Glaser S, Alpini G. Tu1619 Blockade of Substance P Receptor attenuates Cellular Senescence and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis Gastroenterology. 150: S1150-S1151. DOI: 10.1016/S0016-5085(16)33883-5  0.562
2016 McDaniel K, Venter J, Wu N, Wan Y, Francis HL, Zhou T, Glaser S, Alpini G, Meng F. Tu1618 Treatment of Biliary Injury With Small Cholangiocyte Therapy Decreases Stellate Cell Activation via Mediation of Cellular Senescence Gastroenterology. 150: S1150. DOI: 10.1016/S0016-5085(16)33882-3  0.506
2016 Ehrlich L, Hall C, Venter J, Standeford H, Meng F, Lairmore TC, Alpini G, Glaser S. Tu1616 miR-125b Negatively Regulates Menin Expression and Protects from Liver Fibrosis Gastroenterology. 150: S1150. DOI: 10.1016/S0016-5085(16)33880-X  0.542
2016 McMillin M, DeMorrow S, Venter J, Frampton G, Bai H, Glaser S, Alpini G. Tu1613 Cranial Infusion of Melatonin in a Rat Model of Extrahepatic Cholestasis Reduces Biliary Proliferation and Liver Fibrosis Gastroenterology. 150: S1149. DOI: 10.1016/S0016-5085(16)33877-X  0.59
2016 Hall C, Ehrlich L, White T, O'Brien A, Lairmore TC, Alpini G, Glaser S. Mo1470 Activation of the Apelin(Apelin Receptor Axis in Cholangiocarcinoma Promotes Tumor Growth and Angiogenesis Gastroenterology. 150: S1124. DOI: 10.1016/S0016-5085(16)33793-3  0.482
2016 Hargrove L, Kennedy L, Demieville J, Huynh V, Johnson C, DeMorrow S, Meng F, Bernuzzi F, Invernizzi P, Alpini G, Francis HL. Sa1567 UDCA Treatment Reverses Biliary Proliferation and Hepatic Fibrosis in Mdr2−/−Mice and Human PSC By Decreasing Mast Cell Infiltration and Histamine Release Gastroenterology. 150: S1069. DOI: 10.1016/S0016-5085(16)33610-1  0.383
2016 Wu N, Meng F, Venter J, Francis HL, Standeford H, DeMorrow S, Franchitto A, Onori P, Gaudio E, Alpini G, Glaser S. 750 Melatonin Therapy Reduces Biliary Proliferation and Hepatic Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis (PSC) By Decreased Expression of miR-200b and Angiogenic Factors Gastroenterology. 150: S1046. DOI: 10.1016/S0016-5085(16)33535-1  0.526
2016 McDaniel K, Wan Y, Wu N, Venter J, Francis HL, Zhou T, Kennedy L, Glaser S, Alpini G, Meng F. 745 Inhibition of Hepatic Stellate Cell Activation by Stem Cell Derived Extracellular Vesicles and microRNAs During Cholestatic Liver Injury Gastroenterology. 150: S1044-S1045. DOI: 10.1016/S0016-5085(16)33530-2  0.577
2016 Wan Y, Francis HL, Wu N, McDaniel K, Zhou T, Venter J, Bai H, Glaser S, Alpini G, Meng F. 653 microRNA-34a Regulates Alcoholic Hepatitis Through SIRT1/NF-kappa;B Pathway Gastroenterology. 150: S1043. DOI: 10.1016/S0016-5085(16)33525-9  0.491
2016 Kennedy L, Francis HL, Meng F, Venter J, Hargrove L, Glaser S, Alpini G. 510 microRNA-21 Increases Liver Fibrosis via Modulation of TGF-β1/SMAD Signaling in Bile Duct Ligated (BDL) Mice Gastroenterology. 150: S1038-S1039. DOI: 10.1016/S0016-5085(16)33511-9  0.549
2016 Andry S, DeMorrow S, Alpini G, Grant S, Frampton G, McMillin M. 354 Thrombospondin-1 Promotes Liver Injury and Hepatic Encephalopathy By Activating Transforming Growth Factor β1 During Mouse Models of Acute Liver Failure Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33479-5  0.4
2016 Zhou T, Francis HL, Wan Y, Venter J, Wu N, McDaniel K, Bai H, Glaser S, Alpini G, Meng F. 287 Senescence of Activated Hepatic Stellate Cells Limits Liver Fibrosis During Alcoholic Liver Injury Gastroenterology. 150: S1025. DOI: 10.1016/S0016-5085(16)33471-0  0.585
2016 Kyritsi K, Meng F, Venter J, Francis HL, Wu N, Gaudio E, Franchitto A, Onori P, Hall C, Standeford H, Alpini G, Glaser S. 227 MiR-200b Modulates Angiogenesis and Liver Fibrosis in the Mdr2-/- Model of Primary Sclerosing Cholangitis Gastroenterology. 150: S1021. DOI: 10.1016/S0016-5085(16)33457-6  0.531
2015 Wan Y, Garner J, Wu N, Phillip L, Han Y, McDaniel K, Annable T, Zhou T, Francis H, Glaser S, Huang Q, Alpini G, Meng F. Role of stem cells during diabetic liver injury. Journal of Cellular and Molecular Medicine. PMID 26645107 DOI: 10.1111/Jcmm.12723  0.565
2015 Johnson C, Huynh V, Hargrove L, Kennedy L, Graf-Eaton A, Owens J, Trzeciakowski JP, Hodges K, DeMorrow S, Han Y, Wong L, Alpini G, Francis H. Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling. The American Journal of Pathology. PMID 26597881 DOI: 10.1016/J.Ajpath.2015.09.016  0.329
2015 Jones H, Alpini G, Francis H. Bile acid signaling and biliary functions. Acta Pharmaceutica Sinica. B. 5: 123-128. PMID 26579437 DOI: 10.1016/J.Apsb.2015.01.009  0.313
2015 Mishra J, Verma RK, Alpini G, Meng F, Kumar N. Role of Janus Kinase 3 in Predisposition to Obesity associated Metabolic Syndrome. The Journal of Biological Chemistry. PMID 26451047 DOI: 10.1074/Jbc.M115.670331  0.303
2015 Mancinelli R, Glaser S, Francis H, Carpino G, Franchitto A, Vetuschi A, Sferra R, Pannarale L, Venter J, Meng F, Alpini G, Onori P, Gaudio E. Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00015.2015. PMID 26451003 DOI: 10.1152/Ajpgi.00015.2015  0.596
2015 Venter J, Francis H, Meng F, DeMorrow S, Kennedy L, Standeford H, Hargrove L, Wu N, Wan Y, Frampton G, McMillin M, Marzioni M, Gaudio E, Onori P, Glaser S, ... Alpini G, et al. Development and functional characterization of extrahepatic cholangiocyte lines from normal rats. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 26277684 DOI: 10.1016/J.Dld.2015.07.012  0.494
2015 Maroni L, Haibo B, Ray D, Zhou T, Wan Y, Meng F, Marzioni M, Alpini G. Functional and structural features of cholangiocytes in health and disease. Cellular and Molecular Gastroenterology and Hepatology. 1: 368-380. PMID 26273695 DOI: 10.1016/J.Jcmgh.2015.05.005  0.345
2015 Meng F, Alpini G. Peri-scoping the biliary tree reveals stem cell activation in peribiliary glands in Primary Sclerosing Cholangitis. Journal of Hepatology. PMID 26212028 DOI: 10.1016/J.Jhep.2015.07.015  0.408
2015 Nguyen Q, Anders RA, Alpini G, Bai H. Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 47: 826-35. PMID 26093945 DOI: 10.1016/J.Dld.2015.05.011  0.435
2015 Kim KH, Chen CC, Alpini G, Lau LF. CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB. The Journal of Clinical Investigation. 125: 1886-900. PMID 25822023 DOI: 10.1172/Jci79327  0.428
2015 Ray D, Han Y, Franchitto A, DeMorrow S, Meng F, Venter J, McMillin M, Kennedy L, Francis H, Onori P, Mancinelli R, Gaudio E, Alpini G, Glaser SS. Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. The American Journal of Pathology. 185: 1061-72. PMID 25794706 DOI: 10.1016/J.Ajpath.2014.12.004  0.595
2015 Meng L, Quezada M, Levine P, Han Y, McDaniel K, Zhou T, Lin E, Glaser S, Meng F, Francis H, Alpini G. Functional role of cellular senescence in biliary injury. The American Journal of Pathology. 185: 602-9. PMID 25619959 DOI: 10.1016/J.Ajpath.2014.10.027  0.57
2015 Renzi A, Carpino G, Overi D, Venter J, Valenti P, Alpini G, Gaudio E. Lactoferrin regulate biliary epithelium growth and the activation of hepatic progenitor cell niche Italian Journal of Anatomy and Embryology. 120: 126. DOI: 10.13128/Ijae-16997  0.431
2015 Mancinelli R, Venter J, Glaser S, Alpini G, Pannarale L, Onori P. Gonadotropin-releasing hormone induces biliary proliferation by both paracrine and autocrine mechanisms Italian Journal of Anatomy and Embryology. 120: 41. DOI: 10.13128/Ijae-16883  0.6
2015 Choy P, Sufi J, Glaser S, Alpini G, Heaton N, Williams R, Quaglia A, Syn W, Bubici C, Papa S. PTH-115 Inhibition of mapk signalling promotes cell cycle arrest and sensitises intrahepatic cholangiocarcinoma cells to chemotherapy Gut. 64: A458.2-A459. DOI: 10.1136/Gutjnl-2015-309861.1003  0.576
2015 Kennedy L, Francis HL, Hargrove L, Han Y, Venter J, Standeford HA, Meng F, Alpini G, McDaniel K. Sa1720 Knockdown of microRNA-21 Reduces Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct Ligated (BDL) Mice Gastroenterology. 148: S-1020. DOI: 10.1016/S0016-5085(15)33488-0  0.419
2015 Ray D, Han Y, Venter J, Wu N, Avila S, Wan Y, Standeford HA, McDaniel K, Glaser S, Meng F, Alpini G. Sa1719 Dark Therapy Protects Mdr2−/- Mice From Cholestatic Liver Injury Through miR-34a Regulation of the p53/SIRT-1 Signaling Pathway Gastroenterology. 148: S-1019. DOI: 10.1016/S0016-5085(15)33487-9  0.532
2015 Han Y, Wu N, McDaniel K, Wan Y, Venter J, Annable T, Ray D, Avila S, Francis HL, Glaser S, Meng F, Alpini G. Sa1718 C-Myc-Regulated Biliary Cellular Senescence and Functional Heterogeneity During Cholestatic Liver Injury Gastroenterology. 148: S-1019. DOI: 10.1016/S0016-5085(15)33486-7  0.559
2015 Annable T, McDaniel K, Han Y, Venter J, Wu N, Glaser S, Wan Y, Francis HL, Alpini G, Meng F. Sa1715 Regulation of Cellular Senescence by the microRNA-34a/p53 Axis During Alcoholic Liver Injury Gastroenterology. 148: S-1018-S-1019. DOI: 10.1016/S0016-5085(15)33483-1  0.533
2015 Bai H, Nguyen QP, Alpini G, Anders R. Sa1702 Differential YAP Expression Pattern During Liver Development Determines Its Physiological Role in the Liver Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33470-3  0.428
2015 Ehrlich L, Martinez A, O'Brien A, Venter J, Standeford HA, Lairmore T, Alpini G, Glaser S. Sa1700 The Secretin/Secretin Receptor Axis Modulates Biliary Proliferation Following Cholestatic Injury Through Changes in Menin Expression Gastroenterology. 148: S-1014-S-1015. DOI: 10.1016/S0016-5085(15)33468-5  0.512
2015 McDaniel K, Han Y, Wan Y, Venter J, Ray D, Francis HL, Avila S, Standeford HA, Glaser S, Meng F, Alpini G. 803 microRNA Regulation of Functional Heterogeneity in Human Cholangiocytes Gastroenterology. 148: S-996. DOI: 10.1016/S0016-5085(15)33403-X  0.476
2015 Glaser S, Han Y, Venter J, Martinez A, O'Brien A, Avila S, Wu N, Standeford HA, Meng F, Alpini G. 459 Inhibition of the Secretin/Secretin Receptor Axis Attenuates Biliary Fibrosis During Cholestasis Gastroenterology. 148: S-980. DOI: 10.1016/S0016-5085(15)33351-5  0.516
2015 Wu N, Wan Y, Han Y, Annable T, Ray D, Venter J, Avila S, Standeford HA, Francis HL, Glaser S, Meng F, Alpini G. 457 Impact of MT2 Melatonin Receptor Deletion on Cellular Senescence in Cholangiocytes Isolated From Mice After Cholestatic Liver Injury Gastroenterology. 148: S-980. DOI: 10.1016/S0016-5085(15)33349-7  0.536
2015 Wan Y, Han Y, McDaniel K, Annable T, Wu N, Venter J, Francis HL, Glaser S, Alpini G, Meng F. 236 miR-34a Regulates Cellular Senescence in Activated Hepatic Stellate Cells During Alcohol Induced Hepatic Injury Gastroenterology. 148: S-974. DOI: 10.1016/S0016-5085(15)33327-8  0.563
2014 Martínez AK, Maroni L, Marzioni M, Ahmed ST, Milad M, Ray D, Alpini G, Glaser SS. Mouse models of liver fibrosis mimic human liver fibrosis of different etiologies. Current Pathobiology Reports. 2: 143-153. PMID 25396098 DOI: 10.1007/S40139-014-0050-2  0.6
2014 Han Y, Onori P, Meng F, DeMorrow S, Venter J, Francis H, Franchitto A, Ray D, Kennedy L, Greene J, Renzi A, Mancinelli R, Gaudio E, Glaser S, Alpini G. Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G894-904. PMID 25214401 DOI: 10.1152/Ajpgi.00288.2014  0.611
2014 Ray D, Alpini G, Glaser S. Probiotic Bifidobacterium species: potential beneficial effects in diarrheal disorders. Focus on "Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells". American Journal of Physiology. Cell Physiology. 307: C1081-3. PMID 25209264 DOI: 10.1152/Ajpcell.00300.2014  0.483
2014 Francis H, McDaniel K, Han Y, Liu X, Kennedy L, Yang F, McCarra J, Zhou T, Glaser S, Venter J, Huang L, Levine P, Lai JM, Liu CG, Alpini G, et al. Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury. The Journal of Biological Chemistry. 289: 27526-39. PMID 25118289 DOI: 10.1074/Jbc.M114.602383  0.541
2014 Lleo A, Maroni L, Glaser S, Alpini G, Marzioni M. Role of cholangiocytes in primary biliary cirrhosis. Seminars in Liver Disease. 34: 273-84. PMID 25057951 DOI: 10.1055/S-0034-1383727  0.522
2014 Guerrier M, Attili F, Alpini G, Glaser S. Prolonged administration of secretin to normal rats increases biliary proliferation and secretin-induced ductal secretory activity. Hepatobiliary Surgery and Nutrition. 3: 118-25. PMID 25019073 DOI: 10.3978/J.Issn.2304-3881.2014.04.04  0.588
2014 McMillin M, Frampton G, Thompson M, Galindo C, Standeford H, Whittington E, Alpini G, DeMorrow S. Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline. Journal of Neuroinflammation. 11: 121. PMID 25012628 DOI: 10.1186/1742-2094-11-121  0.407
2014 Glaser S, Han Y, Francis H, Alpini G. Melatonin regulation of biliary functions. Hepatobiliary Surgery and Nutrition. 3: 35-43. PMID 24696836 DOI: 10.3978/J.Issn.2304-3881.2013.10.04  0.599
2014 Renzi A, Mancinelli R, Onori P, Franchitto A, Alpini G, Glaser S, Gaudio E. Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes. Hepatobiliary Surgery and Nutrition. 3: 4-10. PMID 24696833 DOI: 10.3978/J.Issn.2304-3881.2014.01.02  0.535
2014 Meng F, DeMorrow S, Venter J, Frampton G, Han Y, Francis H, Standeford H, Avila S, McDaniel K, McMillin M, Afroze S, Guerrier M, Quezada M, Ray D, Kennedy L, ... ... Alpini G, et al. Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G759-68. PMID 24603459 DOI: 10.1152/Ajpgi.00018.2014  0.516
2014 Glaser S, Meng F, Han Y, Onori P, Chow BK, Francis H, Venter J, McDaniel K, Marzioni M, Invernizzi P, Ueno Y, Lai JM, Huang L, Standeford H, Alvaro D, ... ... Alpini G, et al. Secretin stimulates biliary cell proliferation by regulating expression of microRNA 125b and microRNA let7a in mice. Gastroenterology. 146: 1795-808.e12. PMID 24583060 DOI: 10.1053/J.Gastro.2014.02.030  0.537
2014 Nobili V, Carpino G, Alisi A, De Vito R, Franchitto A, Alpini G, Onori P, Gaudio E. Role of docosahexaenoic acid treatment in improving liver histology in pediatric nonalcoholic fatty liver disease. Plos One. 9: e88005. PMID 24505350 DOI: 10.1371/Journal.Pone.0088005  0.411
2014 Levine P, McDaniel K, Francis H, Kennedy L, Alpini G, Meng F. Molecular mechanisms of stem cell therapy in alcoholic liver disease. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 46: 391-7. PMID 24440312 DOI: 10.1016/J.Dld.2013.11.015  0.395
2014 McDaniel K, Herrera L, Zhou T, Francis H, Han Y, Levine P, Lin E, Glaser S, Alpini G, Meng F. The functional role of microRNAs in alcoholic liver injury. Journal of Cellular and Molecular Medicine. 18: 197-207. PMID 24400890 DOI: 10.1111/Jcmm.12223  0.545
2014 Yang W, Zhang J, Hu B, Wu W, Venter J, Alpini G, Fallon MB. The role of receptor tyrosine kinase activation in cholangiocytes and pulmonary vascular endothelium in experimental hepatopulmonary syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G72-80. PMID 24200956 DOI: 10.1152/Ajpgi.00178.2013  0.305
2014 Jung D, York JP, Wang L, Yang C, Zhang A, Francis HL, Webb P, McKeehan WL, Alpini G, Lesage GD, Moore DD, Xia X. FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway. Pflã¼Gers Archiv : European Journal of Physiology. 466: 1011-9. PMID 24068255 DOI: 10.1007/S00424-013-1364-3  0.383
2014 Mancinelli R, Glaser S, Carpino G, Meng F, Pannarale L, Alpini G, Onori P, Franchitto A. Effect of secretin on biliary epithelium growth by regulating expression of MicroRNA 125b and MicroRNA let7a in mice Italian Journal of Anatomy and Embryology. 119: 118. DOI: 10.13128/Ijae-15957  0.561
2014 Quezada M, McDaniel K, Han Y, Francis HL, Glaser S, Venter J, Alpini G, Meng F. Tu1821 Regulation of the Extrinsic Apoptotic Pathway by MicroRNA-21 in Alcoholic Liver Injury Gastroenterology. 146: S-1006. DOI: 10.1016/S0016-5085(14)63658-1  0.549
2014 Glaser S, DeMorrow S, Meng F, Venter J, Standeford HA, Francis HL, McMillin M, Avila S, Frampton GA, Hargrove L, Han Y, McDaniel K, Guerrier M, Afroze SH, Alpini G. Sa1700 Inhibition of the Substance P/Neurokinin 1 Receptor Signaling Axis Reduces Cholangiocarcinoma Growth In Vivo Gastroenterology. 146: S-954. DOI: 10.1016/S0016-5085(14)63472-7  0.566
2014 Ray D, Venter J, Meng F, DeMorrow S, Standeford HA, Francis HL, McDaniel K, Hargrove L, Gaudio E, Onori P, Franchitto A, Mancinelli R, Glaser S, Alpini G. Sa1699 Local Inhibition of Hepatic GnRH by Vivo-Morpholino Reduces Biliary Proliferation and Ameliorates the Expression of Fibrotic Markers in Cholestatic Rats Gastroenterology. 146: S-954. DOI: 10.1016/S0016-5085(14)63471-5  0.576
2014 Lairmore T, Ammarzahid H, Maté G, Standeford HA, Venter J, Meng F, Afroze SH, Guerrier M, Avila S, Alpini G, Glaser S. Sa1698 Downregulation of Menin by Mir-24-1 Increases Cholangiocarcinoma Proliferation Gastroenterology. 146: S-954. DOI: 10.1016/S0016-5085(14)63470-3  0.555
2014 Milad M, McDaniel K, Han Y, Quezada M, Francis HL, Glaser S, Venter J, Alpini G, Meng F. 698 Signal Transducer and Activator of Transcription (STAT)-3 Regulates MicroRNA Gene Expression in Alcoholic Steatohepatitis Gastroenterology. 146: S-923. DOI: 10.1016/S0016-5085(14)63354-0  0.487
2014 Han Y, Meng F, Glaser S, Venter J, McDaniel K, Francis HL, Alpini G. 646 Translational Control of the Circadian Rhythms by MicroRNA-34a in Human Cholangiocarcinoma Gastroenterology. 146: S-920. DOI: 10.1016/S0016-5085(14)63342-4  0.495
2014 McDaniel K, Han Y, Glaser S, Francis HL, Venter J, Guerrier M, Meng F, Alpini G. 473 Functional Role of Definitive Endoderm Marker FOXA2 in Biliary-Committed Progenitor Cells During Cholestatic Liver Injury Gastroenterology. 146: S-912. DOI: 10.1016/S0016-5085(14)63318-7  0.57
2013 Afroze S, Meng F, Jensen K, McDaniel K, Rahal K, Onori P, Gaudio E, Alpini G, Glaser SS. The physiological roles of secretin and its receptor. Annals of Translational Medicine. 1: 29. PMID 25332973 DOI: 10.3978/J.Issn.2305-5839.2012.12.01  0.588
2013 McDaniel K, Correa R, Zhou T, Johnson C, Francis H, Glaser S, Venter J, Alpini G, Meng F. Functional role of microvesicles in gastrointestinal malignancies. Annals of Translational Medicine. 1: 4. PMID 24432300 DOI: 10.3978/J.Issn.2305-5839.2012.10.01  0.487
2013 Glenister R, McDaniel K, Francis H, Venter J, Jensen K, Dusio G, Gaudio E, Glaser S, Meng F, Alpini G. Therapeutic actions of melatonin on gastrointestinal cancer development and progression. Translational Gastrointestinal Cancer. 2. PMID 24312749 DOI: 10.3978/J.Issn.2224-4778.2012.08.03  0.49
2013 Mishra J, Verma RK, Alpini G, Meng F, Kumar N. Role of Janus kinase 3 in mucosal differentiation and predisposition to colitis. The Journal of Biological Chemistry. 288: 31795-806. PMID 24045942 DOI: 10.1074/Jbc.M113.504126  0.334
2013 Han Y, Glaser S, Meng F, Francis H, Marzioni M, McDaniel K, Alvaro D, Venter J, Carpino G, Onori P, Gaudio E, Alpini G, Franchitto A. Recent advances in the morphological and functional heterogeneity of the biliary epithelium. Experimental Biology and Medicine (Maywood, N.J.). 238: 549-65. PMID 23856906 DOI: 10.1177/1535370213489926  0.543
2013 Jensen KJ, Alpini G, Glaser S. Hepatic nervous system and neurobiology of the liver. Comprehensive Physiology. 3: 655-65. PMID 23720325 DOI: 10.1002/Cphy.C120018  0.564
2013 DeMorrow S, Meng F, Venter J, Leyva-Illades D, Francis H, Frampton G, Pae HY, Quinn M, Onori P, Glaser S, McDaniel K, Mancinelli R, Gaudio E, Alpini G, Franchitto A. Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G250-7. PMID 23703654 DOI: 10.1152/Ajpgi.00140.2013  0.567
2013 Onori P, Mancinelli R, Franchitto A, Carpino G, Renzi A, Brozzetti S, Venter J, Francis H, Glaser S, Jefferson DM, Alpini G, Gaudio E. Role of follicle-stimulating hormone on biliary cyst growth in autosomal dominant polycystic kidney disease. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 914-25. PMID 23617956 DOI: 10.1111/Liv.12177  0.536
2013 Mancinelli R, Franchitto A, Glaser S, Meng F, Onori P, Demorrow S, Francis H, Venter J, Carpino G, Baker K, Han Y, Ueno Y, Gaudio E, Alpini G. GABA induces the differentiation of small into large cholangiocytes by activation of Ca(2+) /CaMK I-dependent adenylyl cyclase 8. Hepatology (Baltimore, Md.). 58: 251-63. PMID 23389926 DOI: 10.1002/Hep.26308  0.497
2013 De Minicis S, Kisseleva T, Francis H, Baroni GS, Benedetti A, Brenner D, Alvaro D, Alpini G, Marzioni M. Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 45: 450-9. PMID 23177172 DOI: 10.1016/J.Dld.2012.10.008  0.349
2013 Renzi A, DeMorrow S, Onori P, Carpino G, Mancinelli R, Meng F, Venter J, White M, Franchitto A, Francis H, Han Y, Ueno Y, Dusio G, Jensen KJ, Greene JJ, ... ... Alpini G, et al. Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats. Hepatology (Baltimore, Md.). 57: 1130-41. PMID 23080076 DOI: 10.1002/Hep.26105  0.595
2013 Meng F, Francis H, McDaniel K, Han Y, Glaser S, Alpini G. 1063 microRNAS IN THE p53 NETWORK: EPITHELIAL–MESENCHYMAL TRANSITION IN FUNCTIONAL TUMOR-INITIATING CELLS OF HUMAN GALLBLADDER CANCER Journal of Hepatology. 58: S436. DOI: 10.1016/S0168-8278(13)61064-8  0.389
2013 Levine P, McDaniel K, Francis HL, Glaser S, Han Y, Sharma J, Liu C, Venter J, Short-Baker KK, Alpini G, Meng F. Mo1778 Regulation of MicroRNAs by p53 in Functional Tumor-Initiating Cells of Human Gallbladder Cancer Gastroenterology. 144: S-1024. DOI: 10.1016/S0016-5085(13)63805-6  0.483
2013 Levine P, McDaniel K, Han Y, Francis HL, Glaser S, Venter J, Tsukamoto H, Alpini G, Meng F. Su1718 Regulation of MicroRNA-21 by Interleukin-6 During Alcoholic Liver Injury Gastroenterology. 144: S-1005. DOI: 10.1016/S0016-5085(13)63734-8  0.544
2013 Johnson C, Han Y, Meng F, Francis HL, Venter J, McDaniel K, Onori P, Ueno Y, Gaudio E, Glaser S, Alpini G. 368 Regulation of MicroRNA Expression by Secretin During Cholestatic Liver Injury Gastroenterology. 144: S-943. DOI: 10.1016/S0016-5085(13)63508-8  0.573
2012 Bai H, Zhang N, Xu Y, Chen Q, Khan M, Potter JJ, Nayar SK, Cornish T, Alpini G, Bronk S, Pan D, Anders RA. Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology (Baltimore, Md.). 56: 1097-107. PMID 22886419 DOI: 10.1002/Hep.25769  0.481
2012 Meng F, Glaser SS, Francis H, Yang F, Han Y, Stokes A, Staloch D, McCarra J, Liu J, Venter J, Zhao H, Liu X, Francis T, Swendsen S, Liu CG, ... ... Alpini G, et al. Epigenetic regulation of miR-34a expression in alcoholic liver injury. The American Journal of Pathology. 181: 804-17. PMID 22841474 DOI: 10.1016/J.Ajpath.2012.06.010  0.514
2012 Xia X, Jung D, Webb P, Zhang A, Zhang B, Li L, Ayers SD, Gabbi C, Ueno Y, Gustafsson JÅ, Alpini G, Moore DD, Lesage GD. Liver X receptor β and peroxisome proliferator-activated receptor δ regulate cholesterol transport in murine cholangiocytes. Hepatology (Baltimore, Md.). 56: 2288-96. PMID 22729460 DOI: 10.1002/Hep.25919  0.38
2012 Johnson C, Han Y, Hughart N, McCarra J, Alpini G, Meng F. Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer. Translational Gastrointestinal Cancer. 1: 58-70. PMID 22724089 DOI: 10.3978/J.Issn.2224-4778.2011.11.02  0.344
2012 Francis H, Bohanan J, Alpini G. Hedgehog signalling and LSEC capillarisation: stopping this one in its tracks. Gut. 61: 1243-4. PMID 22589203 DOI: 10.1136/Gutjnl-2012-302057  0.466
2012 Nobili V, Carpino G, Alisi A, Franchitto A, Alpini G, De Vito R, Onori P, Alvaro D, Gaudio E. Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). 56: 2142-53. PMID 22467277 DOI: 10.1002/Hep.25742  0.431
2012 Cardinale V, Wang Y, Carpino G, Mendel G, Alpini G, Gaudio E, Reid LM, Alvaro D. The biliary tree--a reservoir of multipotent stem cells. Nature Reviews. Gastroenterology & Hepatology. 9: 231-40. PMID 22371217 DOI: 10.1038/Nrgastro.2012.23  0.36
2012 Francis H, Meng F, Gaudio E, Alpini G. Histamine regulation of biliary proliferation. Journal of Hepatology. 56: 1204-6. PMID 22245899 DOI: 10.1016/J.Jhep.2011.09.023  0.348
2012 Jensen K, Marzioni M, Munshi K, Afroze S, Alpini G, Glaser S. Autocrine regulation of biliary pathology by activated cholangiocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G473-83. PMID 22194419 DOI: 10.1152/Ajpgi.00482.2011  0.599
2012 Meng F, Francis H, Glaser S, Han Y, DeMorrow S, Stokes A, Staloch D, Venter J, White M, Ueno Y, Reid LM, Alpini G. Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration. Hepatology (Baltimore, Md.). 55: 209-21. PMID 21932404 DOI: 10.1002/Hep.24673  0.552
2012 Francis H, DeMorrow S, Venter J, Onori P, White M, Gaudio E, Francis T, Greene JF, Tran S, Meininger CJ, Alpini G. Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma. Gut. 61: 753-64. PMID 21873469 DOI: 10.1136/Gutjnl-2011-300007  0.359
2012 Meng F, Glaser SS, Francis H, DeMorrow S, Han Y, Passarini JD, Stokes A, Cleary JP, Liu X, Venter J, Kumar P, Priester S, Hubble L, Staloch D, Sharma J, ... ... Alpini G, et al. Functional analysis of microRNAs in human hepatocellular cancer stem cells. Journal of Cellular and Molecular Medicine. 16: 160-73. PMID 21352471 DOI: 10.1111/J.1582-4934.2011.01282.X  0.516
2012 Renzi A, DeMorrow S, Carpino G, Glaser S, Alpini G, Gaudio E. Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes Italian Journal of Anatomy and Embryology. 117: 160. DOI: 10.13128/Ijae-12271  0.579
2012 Mancinelli R, Brozzetti S, Venter J, Pannarale L, Alpini G, Onori P. Follicle-Stimulating Hormone influences biliary epithelium growth in Autosomal Dominant Polycystic Kidney Disease Italian Journal of Anatomy and Embryology. 117: 110. DOI: 10.13128/Ijae-12193  0.406
2012 Franchitto A, Mancinelli R, Renzi A, Francis H, Alpini G. Histamine induces small and large cholangiocytes growth by activation of IP3/Ca2+ and cAMP-dependent signalling mechanisms Italian Journal of Anatomy and Embryology. 117: 76. DOI: 10.13128/Ijae-11984  0.367
2012 Glaser SS, Meng F, Venter J, Han Y, White M, Alpini G. Abstract 3023: Decreased neutral endopeptidase expression regulates the autocrine proliferative effects of substance P on cholangiocarcinoma growth Cancer Research. 72: 3023-3023. DOI: 10.1158/1538-7445.Am2012-3023  0.534
2012 Han Y, Glaser S, McCarra J, Venter J, White M, Dusio G, Francis HL, Johnson C, Tsukamoto H, Meng F, Alpini G. 931 Regulation of Hepatic Stem/Progenitor Phenotype by Melatonin During Alcoholic Liver Injury Gastroenterology. 142: S-935. DOI: 10.1016/S0016-5085(12)63629-4  0.521
2012 Johnson C, Francis HL, Glaser S, Han Y, Venter J, Liu C, White M, McCarra J, Tsukamoto H, Alpini G, Meng F. 930 Regulation of Hepatic Stellate Cell Activation by MicroRNA Let-7 Family During Alcoholic Liver Injury Gastroenterology. 142: S-935. DOI: 10.1016/S0016-5085(12)63628-2  0.523
2012 Dusio G, Renzi A, Meng F, DeMorrow S, Venter J, White M, Francis HL, Han Y, Onori P, Baker KK, Butler W, Invernizzi P, Gaudio E, Alpini G, Glaser S. 832 Increased Synthesis of Melatonin From Pineal Gland and Cholangiocytes (by Prolonged Exposure of Cholestatic Rats to Complete Dark) Leads to Inhibition of Biliary Hyperplasia by Autocrine/Paracrine Mechanisms Gastroenterology. 142: S-930. DOI: 10.1016/S0016-5085(12)63609-9  0.504
2012 Han Y, Francis HL, Glaser S, McCarra J, Alpini G, Sharma J, Dusio G, Liu C, Johnson C, Meng F. 740 Epigenetic Regulation of MicroRNA-200 Family in Human Gall Bladder Cancer Stem Cells Gastroenterology. 142: S-926-S-927. DOI: 10.1016/S0016-5085(12)63594-X  0.461
2012 Meng F, Jensen KJ, Afroze S, Han Y, Munshi M, Alpini G, Guerrier M, Dostal DE, Glaser S. 292 Functional Roles of MicroRNAs in Mechanical Stress Induced Mesenchymal Transition During Cholestatic Liver Injury Gastroenterology. 142: S-910. DOI: 10.1016/S0016-5085(12)63532-X  0.543
2011 Meng F, Alpini G. Confocal laser endomicroscopy in dynamic evaluation of hepatic apoptosis in vivo American Journal of Physiology - Gastrointestinal and Liver Physiology. 301. PMID 21868634 DOI: 10.1152/Ajpgi.00310.2011  0.385
2011 Han Y, Demorrow S, Invernizzi P, Jing Q, Glaser S, Renzi A, Meng F, Venter J, Bernuzzi F, White M, Francis H, Lleo A, Marzioni M, Onori P, Alvaro D, ... ... Alpini G, et al. Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G623-33. PMID 21778461 DOI: 10.1152/Ajpgi.00118.2011  0.528
2011 Renzi A, Glaser S, Demorrow S, Mancinelli R, Meng F, Franchitto A, Venter J, White M, Francis H, Han Y, Alvaro D, Gaudio E, Carpino G, Ueno Y, Onori P, ... Alpini G, et al. Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G634-43. PMID 21757639 DOI: 10.1152/Ajpgi.00206.2011  0.575
2011 Alpini G, Glaser SS, Zhang JP, Francis H, Han Y, Gong J, Stokes A, Francis T, Hughart N, Hubble L, Zhuang SM, Meng F. Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. Journal of Hepatology. 55: 1339-45. PMID 21703189 DOI: 10.1016/J.Jhep.2011.04.015  0.477
2011 Glaser S, Gaudio E, Renzi A, Mancinelli R, Ueno Y, Venter J, White M, Kopriva S, Chiasson V, DeMorrow S, Francis H, Meng F, Marzioni M, Franchitto A, Alvaro D, ... ... Alpini G, et al. Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G297-305. PMID 21596993 DOI: 10.1152/ajpgi.00418.2010  0.528
2011 Chu AS, Diaz R, Hui JJ, Yanger K, Zong Y, Alpini G, Stanger BZ, Wells RG. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis. Hepatology (Baltimore, Md.). 53: 1685-95. PMID 21520179 DOI: 10.1002/Hep.24206  0.414
2011 Omenetti A, Bass LM, Anders RA, Clemente MG, Francis H, Guy CD, McCall S, Choi SS, Alpini G, Schwarz KB, Diehl AM, Whitington PF. Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia. Hepatology (Baltimore, Md.). 53: 1246-58. PMID 21480329 DOI: 10.1002/Hep.24156  0.389
2011 Turner R, Lozoya O, Wang Y, Cardinale V, Gaudio E, Alpini G, Mendel G, Wauthier E, Barbier C, Alvaro D, Reid LM. Human hepatic stem cell and maturational liver lineage biology. Hepatology (Baltimore, Md.). 53: 1035-45. PMID 21374667 DOI: 10.1002/Hep.24157  0.408
2011 Munshi MK, Priester S, Gaudio E, Yang F, Alpini G, Mancinelli R, Wise C, Meng F, Franchitto A, Onori P, Glaser SS. Regulation of biliary proliferation by neuroendocrine factors: implications for the pathogenesis of cholestatic liver diseases. The American Journal of Pathology. 178: 472-84. PMID 21281779 DOI: 10.1016/J.Ajpath.2010.09.043  0.615
2011 Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, Francis H, Venter J, Kopriva S, Mancinelli R, Carpino G, Stagnitti F, Ueno Y, Han Y, Meng F, et al. Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1. Hepatology (Baltimore, Md.). 53: 628-39. PMID 21274883 DOI: 10.1002/Hep.24041  0.522
2011 DeMorrow S, Onori P, Venter J, Invernizzi P, Frampton G, White M, Franchitto A, Kopriva S, Bernuzzi F, Francis H, Coufal M, Glaser S, Fava G, Meng F, Alvaro D, ... ... Alpini G, et al. Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion. American Journal of Physiology. Cell Physiology. 300: C1078-89. PMID 21270292 DOI: 10.1152/Ajpcell.00358.2010  0.534
2011 Dutta AK, Khimji AK, Kresge C, Bugde A, Dougherty M, Esser V, Ueno Y, Glaser SS, Alpini G, Rockey DC, Feranchak AP. Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium. The Journal of Biological Chemistry. 286: 766-76. PMID 21041307 DOI: 10.1074/Jbc.M110.164970  0.523
2011 Carpino G, Nobili V, Onori P, Alisi A, Franchitto A, Vito RD, Mancinelli R, Alpini G, Alvaro D, Gaudio E. Hepatic progenitor cells as a source of adipokines and glucagon-like peptide-1 in pediatric nonalcoholic fatty liver disease. Italian Journal of Anatomy and Embryology. 116: 40-40. DOI: 10.13128/Ijae-9992  0.442
2011 Mancinelli R, Renzi A, Franchitto A, Carpino G, DeMorrow S, Francis H, Alpini G, Onori P. Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by downregulation of CLOCK genes Italian Journal of Anatomy and Embryology. 116: 107. DOI: 10.13128/Ijae-10117  0.404
2011 Venter J, Francis H, Meng F, White M, Staloch D, Renzi A, Onori P, Butler W, Gaudio E, Alpini G. Initial Development and Characterization of Primary Cultures of Small and Large Intrahepatic Cholangiocytes From Normal Rat Liver Gastroenterology. 140: S-937. DOI: 10.1016/S0016-5085(11)63886-9  0.381
2011 Glaser S, Mancinelli R, Onori P, Franchitto A, Venter J, White M, Meng F, Renzi A, Carpino G, Butler W, Sferra R, Staloch D, Gaudio E, Alpini G. Ischemia Reperfusion of the Hepatic Artery Induces the Functional Damage of Large Bile Ducts by Changes in the Expression of the Cholangiocyte Angiogenic Factors, VEGF and Angiopoietin Gastroenterology. 140: S-937. DOI: 10.1016/S0016-5085(11)63884-5  0.526
2011 Han Y, Meng F, Glaser S, Francis H, Sharma J, Liu C, Venter J, White M, Stokes A, Hubble L, Staloch D, Alpini G. Aberrant Expression of the miR-17-92 Cluster in Human Cholangiocarcinoma Stem Cells Gastroenterology. 140: S-889. DOI: 10.1016/S0016-5085(11)63695-0  0.466
2011 DeMorrow S, Onori P, Mancinelli R, Venter J, Franchitto A, White M, Ueno Y, Francis H, Butler W, Gaudio E, Alpini G. Selective Activation of the Serotonin Receptor 2B Isoform Increases Cholangiocyte Growth and Induces the Expression of the Fibroblast Growth Factor 1 (FGF1) Gastroenterology. 140: S-888. DOI: 10.1016/S0016-5085(11)63691-3  0.386
2011 Renzi A, DeMorrow S, Glaser S, Onori P, Venter J, Mancinelli R, Franchitto A, White M, Francis H, Ueno Y, Meng F, Butler W, Gaudio E, Alpini G. Modulation of the Biliary Expression of Arylalkylamine N-Acetyltransferase (AANAT, the Key Enzyme Regulating Melatonin Synthesis) Alters the Proliferative/Apoptotic Responses of Cholangiocytes to Liver Injury In Vivo and In Vitro Gastroenterology. 140: S-887. DOI: 10.1016/S0016-5085(11)63690-1  0.565
2010 Yang F, Gaudio E, Onori P, Wise C, Alpini G, Glaser SS. Mechanisms of Biliary Damage. Journal of Cell Death. 3: 13-21. PMID 28469475  0.51
2010 Yang F, Gaudio E, Onori P, Wise C, Alpini G, Glaser SS. Mechanisms of Biliary Damage. Journal of Cell Death. 2010: 13-21. PMID 22924014 DOI: 10.4137/JCD.S2785  0.51
2010 Mancinelli R, Onori P, Demorrow S, Francis H, Glaser S, Franchitto A, Carpino G, Alpini G, Gaudio E. Role of sex hormones in the modulation of cholangiocyte function. World Journal of Gastrointestinal Pathophysiology. 1: 50-62. PMID 21607142 DOI: 10.4291/Wjgp.V1.I2.50  0.607
2010 Onori P, Gaudio E, Franchitto A, Alpini G, Francis H. Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes. World Journal of Gastrointestinal Pathophysiology. 1: 38-49. PMID 21607141 DOI: 10.4291/Wjgp.V1.I2.38  0.352
2010 Woo K, Sathe M, Kresge C, Esser V, Ueno Y, Venter J, Glaser SS, Alpini G, Feranchak AP. Adenosine triphosphate release and purinergic (P2) receptor-mediated secretion in small and large mouse cholangiocytes. Hepatology (Baltimore, Md.). 52: 1819-28. PMID 20827720 DOI: 10.1002/Hep.23883  0.506
2010 Franchitto A, Torrice A, Semeraro R, Napoli C, Nuzzo G, Giuliante F, Alpini G, Carpino G, Berloco PB, Izzo L, Bolognese A, Onori P, Renzi A, Cantafora A, Gaudio E, et al. Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologically. The American Journal of Pathology. 177: 1779-90. PMID 20724592 DOI: 10.2353/Ajpath.2010.091171  0.365
2010 Glaser S, Lam IP, Franchitto A, Gaudio E, Onori P, Chow BK, Wise C, Kopriva S, Venter J, White M, Ueno Y, Dostal D, Carpino G, Mancinelli R, Butler W, ... ... Alpini G, et al. Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation. Hepatology (Baltimore, Md.). 52: 204-14. PMID 20578263 DOI: 10.1002/Hep.23657  0.556
2010 Glaser S, Wang M, Ueno Y, Venter J, Wang K, Chen H, Alpini G, Holterman AX. Differential transcriptional characteristics of small and large biliary epithelial cells derived from small and large bile ducts American Journal of Physiology - Gastrointestinal and Liver Physiology. 299: G769-G777. PMID 20576918 DOI: 10.1152/Ajpgi.00237.2010  0.531
2010 Glaser SS, Alpini G. Introduction to Mini-Symposium on Cholangiocyte Pathophysiology--Part II. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 389. PMID 20392677 DOI: 10.1016/J.Dld.2010.03.021  0.41
2010 Glaser S, Onori P, Gaudio E, Ueno Y, Pannarale L, Franchitto A, Francis H, Mancinelli R, Carpino G, Venter J, White M, Kopriva S, Vetuschi A, Sferra R, Alpini G. Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 709-17. PMID 20303838 DOI: 10.1016/J.Dld.2010.02.008  0.565
2010 Mancinelli R, Franchitto A, Gaudio E, Onori P, Glaser S, Francis H, Venter J, Demorrow S, Carpino G, Kopriva S, White M, Fava G, Alvaro D, Alpini G. After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes. The American Journal of Pathology. 176: 1790-800. PMID 20185575 DOI: 10.2353/Ajpath.2010.090677  0.527
2010 Alpini G. Introduction to mini-symposium on cholangiocyte pathophysiology--part I. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 237. PMID 20171945 DOI: 10.1016/J.Dld.2010.01.015  0.331
2010 Glaser SS, Onori P, Wise C, Yang F, Marzioni M, Alvaro D, Franchitto A, Mancinelli R, Alpini G, Munshi MK, Gaudio E. Recent advances in the regulation of cholangiocyte proliferation and function during extrahepatic cholestasis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 245-52. PMID 20153989 DOI: 10.1016/J.Dld.2010.01.008  0.581
2010 Onori P, Franchitto A, Mancinelli R, Carpino G, Alvaro D, Francis H, Alpini G, Gaudio E. Polycystic liver diseases. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 261-71. PMID 20138815 DOI: 10.1016/J.Dld.2010.01.006  0.41
2010 Glaser SS, Alpini G. International hepatology. Journal of Hepatology. 52: 450-1. PMID 20129691 DOI: 10.1016/j.jhep.2009.11.021  0.328
2010 Glaser SS, Gaudio E, Alpini G. Vascular factors, angiogenesis and biliary tract disease. Current Opinion in Gastroenterology. 26: 246-50. PMID 20061944 DOI: 10.1097/Mog.0B013E3283369D19  0.48
2010 Torrice A, Cardinale V, Gatto M, Semeraro R, Napoli C, Onori P, Alpini G, Gaudio E, Alvaro D. Polycystins play a key role in the modulation of cholangiocyte proliferation Digestive and Liver Disease. 42: 377-385. PMID 19897428 DOI: 10.1016/J.Dld.2009.09.008  0.345
2010 Onori P, Mancinelli R, Glaser S, Franchitto A, Pannarale L, Sferra R, Vetuschi A, Alpini G, Gaudio E. Effect of taurocholic acid on biliary injury in course of hepatic artery ligation in cholestatic rats Italian Journal of Anatomy and Embryology. 115: 131-131. DOI: 10.13128/Ijae-8893  0.524
2010 Franchitto A, Onori P, Carpino G, Francis H, Mancinelli R, Alpini G, Gaudio E. Role of secretin in large cholangiocyte proliferation during extrahepatic cholestasisinduced by bile duct ligation in mice Italian Journal of Anatomy and Embryology. 115: 71-71. DOI: 10.13128/Ijae-8829  0.324
2010 Meng F, Glaser S, Han Y, Francis H, Stokes A, Sharma J, Liu C, Hubble L, Alpini G. P7 Associated MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human cholangiocarcinoma stem cells Digestive and Liver Disease. 42: S317-S318. DOI: 10.1016/S1590-8658(10)60541-5  0.459
2010 Meng F, Francis H, DeMorrow S, Glaser S, Stokes A, Han Y, Venter J, White M, Kopriva S, Alpini G. M1030 Involvement of Colony Stimulating Factors in Biliary Epithelial Remodeling After Partial Hepatectomy Gastroenterology. 138: S-825. DOI: 10.1016/S0016-5085(10)63804-8  0.474
2010 Yang F, Wise C, Miller TD, Francis H, Venter J, Alpini G, Kopriva S, White M, Meng F, Munshi M, Glaser S. M1005 Omeprazole Inhibits Biliary Proliferation and Ductal Bile Secretion in Cholestatic Rats by the Activation of Aryl Hydrocarbon Receptors on Cholangiocytes Gastroenterology. 138: S-820. DOI: 10.1016/S0016-5085(10)63779-1  0.535
2010 Han Y, DeMorrow S, Glaser S, Venter J, Francis H, Kopriva S, Wise C, White M, Meng F, Butler W, Huang L, Alpini G. 631 Decreased Melatonin Synthesis in Cholangiocarcinoma (CCA) Suppresses Its Antiproliferative Actions by Upregulation of Clock Gene Gastroenterology. 138: S-792-S-793. DOI: 10.1016/S0016-5085(10)63651-7  0.468
2009 Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G. H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo. Molecular Cancer Research : McR. 7: 1704-13. PMID 19825989 DOI: 10.1158/1541-7786.Mcr-09-0261  0.36
2009 Omenetti A, Syn WK, Jung Y, Francis H, Porrello A, Witek RP, Choi SS, Yang L, Mayo MJ, Gershwin ME, Alpini G, Diehl AM. Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production. Hepatology (Baltimore, Md.). 50: 518-27. PMID 19575365 DOI: 10.1002/Hep.23019  0.473
2009 Glaser SS, Alpini G. Activation of the cholehepatic shunt as a potential therapy for primary sclerosing cholangitis. Hepatology (Baltimore, Md.). 49: 1795-7. PMID 19475683 DOI: 10.1002/Hep.22969  0.443
2009 Strazzabosco M, Fiorotto R, Melero S, Glaser S, Francis H, Spirli C, Alpini G. Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation. Hepatology (Baltimore, Md.). 50: 244-52. PMID 19444869 DOI: 10.1002/Hep.22926  0.495
2009 Mancinelli R, Onori P, Gaudio E, DeMorrow S, Franchitto A, Francis H, Glaser S, Carpino G, Venter J, Alvaro D, Kopriva S, White M, Kossie A, Savage J, Alpini G. Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G11-26. PMID 19389804 DOI: 10.1152/Ajpgi.00025.2009  0.545
2009 Lam IP, Lee LT, Choi HS, Alpini G, Chow BK. Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP). American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G90-7. PMID 19372104 DOI: 10.1152/Ajpgi.00094.2009  0.352
2009 Onori P, DeMorrow S, Gaudio E, Franchitto A, Mancinelli R, Venter J, Kopriva S, Ueno Y, Alvaro D, Savage J, Alpini G, Francis H. Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis. International Journal of Cancer. Journal International Du Cancer. 125: 565-76. PMID 19358267 DOI: 10.1002/Ijc.24271  0.337
2009 Fava G, Demorrow S, Gaudio E, Franchitto A, Onori P, Carpino G, Glaser S, Francis H, Coufal M, Marucci L, Alvaro D, Marzioni M, Horst T, Mancinelli R, Benedetti A, ... Alpini G, et al. Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression. Liver International : Official Journal of the International Association For the Study of the Liver. 29: 1031-42. PMID 19291182 DOI: 10.1111/J.1478-3231.2009.01997.X  0.471
2009 Glaser SS, Gaudio E, Miller T, Alvaro D, Alpini G. Cholangiocyte proliferation and liver fibrosis. Expert Reviews in Molecular Medicine. 11: e7. PMID 19239726 DOI: 10.1017/S1462399409000994  0.63
2009 Glaser SS, Gaudio E, Rao A, Pierce LM, Onori P, Franchitto A, Francis HL, Dostal DE, Venter JK, DeMorrow S, Mancinelli R, Carpino G, Alvaro D, Kopriva SE, Savage JM, ... Alpini GD, et al. Morphological and functional heterogeneity of the mouse intrahepatic biliary epithelium. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 456-69. PMID 19204666 DOI: 10.1038/Labinvest.2009.6  0.548
2009 Marzioni M, Invernizzi P, Candelaresi C, Maggioni M, Saccomanno S, Selmi C, Rychlicki C, Agostinelli L, Cassani B, Miozzo M, Pasini S, Fava G, Alpini G, Benedetti A. Human cholangiocarcinoma development is associated with dysregulation of opioidergic modulation of cholangiocyte growth. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 41: 523-33. PMID 18948067 DOI: 10.1016/J.Dld.2008.09.011  0.345
2009 Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Venter J, Rychlicki C, Fava G, Francis H, Trozzi L, Benedetti A. Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis. Gut. 58: 990-7. PMID 18829977 DOI: 10.1136/Gut.2008.150870  0.353
2009 Marzioni M, Fava G, Alvaro D, Alpini G, Benedetti A. Control of cholangiocyte adaptive responses by visceral hormones and neuropeptides. Clinical Reviews in Allergy & Immunology. 36: 13-22. PMID 18548352 DOI: 10.1007/S12016-008-8090-1  0.37
2009 Mancino A, Mancino MG, Glaser SS, Alpini G, Bolognese A, Izzo L, Francis H, Onori P, Franchitto A, Ginanni-Corradini S, Gaudio E, Alvaro D. Estrogens stimulate the proliferation of human cholangiocarcinoma by inducing the expression and secretion of vascular endothelial growth factor. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 41: 156-63. PMID 18395502 DOI: 10.1016/J.Dld.2008.02.015  0.518
2009 Mancinelli R, Onori P, Gaudio E, Carpino G, Franchitto A, Francis H, Meininger C, DeMorrow S, Glaser S, Venter J, Kopriva S, White M, Kossie AN, Alvaro D, Savage J, ... Alpini G, et al. S1581 Stimulation of Biliary Proliferation By Follicle Stimulating Hormone (FSH) Is Mediated By Increased Expression of Nitric Oxide Synthase in Cholangiocytes Gastroenterology. 136: A-818. DOI: 10.1016/S0016-5085(09)63771-9  0.487
2009 Mancinelli R, Onori P, Gaudio E, Franchitto A, Bhardwaj A, Glaser S, Francis H, Venter J, Carpino G, Sferra R, Vetuschi A, Alvaro D, Supowit S, DiPette DJ, Chiasson VL, ... Alpini G, et al. S1579 Bile Duct Damage Following Hepatic Artery and Portal Vein Ischemia Reperfusion Injury in Cholestatic Bile Duct Ligated (BDL) Rats Is Associated with Changes in the Expression of Cholangiocyte Angiogenic Factors Gastroenterology. 136: A-818. DOI: 10.1016/S0016-5085(09)63769-0  0.548
2009 Francis H, DeMorrow S, Gaudio E, Ueno Y, Venter J, Onori P, Franchitto A, Carpino G, Marzioni M, Mancinelli R, Glaser S, Kopriva S, Kossie AN, White M, Savage J, ... Alpini G, et al. S1578 The Differential Effects of Histamine Receptor Subtypes On Cholangiocyte Proliferation of Normal Rats Gastroenterology. 136: A-817-A-818. DOI: 10.1016/S0016-5085(09)63768-9  0.504
2009 Fava G, DeMorrow S, Francis H, Gaudio E, Onori P, Glaser S, Franchitto A, Alvaro D, Marzioni M, Mancinelli R, Benedetti A, Marucci L, Coufal M, Carpino G, Venter J, ... Alpini G, et al. S1577 Endothelin Inhibits Both In Vivo and In Vitro Cholangiocarcinoma Growth By a Decrease in Vascular Endothelial Growth Factor (VEGF) Expression Gastroenterology. 136: A-817. DOI: 10.1016/S0016-5085(09)63767-7  0.472
2009 Mancinelli R, Gaudio E, Onori P, Francis H, Franchitto A, Carpino G, DeMorrow S, Glaser S, Alvaro D, Ueno Y, Fava G, Venter J, Marzioni M, Kopriva S, Alpini G. 344 Novel Evidence for CaMK I-Dependent Differentiation of Small Cholangiocytes Into Functional Large Cholangiocytes Following Gamma-Aminobutyric Acid (GABA) Treatment Gastroenterology. 136: A-800. DOI: 10.1016/S0016-5085(09)63690-8  0.444
2008 Alpini G, Invernizzi P, Gaudio E, Venter J, Kopriva S, Bernuzzi F, Onori P, Franchitto A, Coufal M, Frampton G, Alvaro D, Lee SP, Marzioni M, Benedetti A, DeMorrow S. Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth. Cancer Research. 68: 9184-93. PMID 19010890 DOI: 10.1158/0008-5472.Can-08-2133  0.327
2008 Omenetti A, Porrello A, Jung Y, Yang L, Popov Y, Choi SS, Witek RP, Alpini G, Venter J, Vandongen HM, Syn WK, Baroni GS, Benedetti A, Schuppan D, Diehl AM. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. The Journal of Clinical Investigation. 118: 3331-42. PMID 18802480 DOI: 10.1172/Jci35875  0.414
2008 Fava G, Alpini G, Rychlicki C, Saccomanno S, DeMorrow S, Trozzi L, Candelaresi C, Venter J, Di Sario A, Marzioni M, Bearzi I, Glaser S, Alvaro D, Marucci L, Francis H, et al. Leptin enhances cholangiocarcinoma cell growth. Cancer Research. 68: 6752-61. PMID 18701500 DOI: 10.1158/0008-5472.Can-07-6682  0.556
2008 Gatto M, Drudi-Metalli V, Torrice A, Alpini G, Cantafora A, Blotta I, Alvaro D. Insulin-like growth factor-1 isoforms in rat hepatocytes and cholangiocytes and their involvement in protection against cholestatic injury. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 986-94. PMID 18607346 DOI: 10.1038/Labinvest.2008.63  0.361
2008 Glaser S, DeMorrow S, Francis H, Ueno Y, Gaudio E, Vaculin S, Venter J, Franchitto A, Onori P, Vaculin B, Marzioni M, Wise C, Pilanthananond M, Savage J, Pierce L, ... ... Alpini G, et al. Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G124-G136. PMID 18511743 DOI: 10.1152/Ajpgi.00536.2007  0.603
2008 Yang L, Jung Y, Omenetti A, Witek RP, Choi S, Vandongen HM, Huang J, Alpini GD, Diehl AM. Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. Stem Cells (Dayton, Ohio). 26: 2104-13. PMID 18511600 DOI: 10.1634/Stemcells.2008-0115  0.33
2008 Francis H, Glaser S, Demorrow S, Gaudio E, Ueno Y, Venter J, Dostal D, Onori P, Franchitto A, Marzioni M, Vaculin S, Vaculin B, Katki K, Stutes M, Savage J, ... Alpini G, et al. Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. American Journal of Physiology. Cell Physiology. 295: C499-513. PMID 18508907 DOI: 10.1152/Ajpcell.00369.2007  0.508
2008 Wise C, Pilanthananond M, Perry BF, Alpini G, McNeal M, Glaser SS. Mechanisms of biliary carcinogenesis and growth. World Journal of Gastroenterology : Wjg. 14: 2986-9. PMID 18494047 DOI: 10.3748/Wjg.14.2986  0.5
2008 Alvaro D, Onori P, Alpini G, Franchitto A, Jefferson DM, Torrice A, Cardinale V, Stefanelli F, Mancino MG, Strazzabosco M, Angelico M, Attili A, Gaudio E. Morphological and functional features of hepatic cyst epithelium in autosomal dominant polycystic kidney disease. The American Journal of Pathology. 172: 321-32. PMID 18202196 DOI: 10.2353/Ajpath.2008.070293  0.387
2008 DeMorrow S, Francis H, Gaudio E, Ueno Y, Venter J, Onori P, Franchitto A, Vaculin B, Vaculin S, Alpini G. Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G506-19. PMID 18096608 DOI: 10.1152/Ajpgi.00304.2007  0.368
2008 Wise C, Venter J, Alpini G, Vaculin BT, Glaser S. S1591 Chronic Administration of Nicotine Induces Biliary Proliferation in Both Normal and Rats with Extrahepatic Cholestasis Induced By Bile Duct Ligation (BDL) Gastroenterology. 134: A-777-A-778. DOI: 10.1016/S0016-5085(08)63631-8  0.515
2008 Glaser S, Gaudio E, Francis H, Ueno Y, Onori P, Franchitto A, Venter J, Alvaro D, Vaculin BT, Kopriva S, Savage J, Alpini G. S1590 Bile Acid Feeding Prevents Hepatic Artery Ligation-Induced Bile Duct Injury in Bile Duct Ligated Rats (BDL) By PI3K/AKT-Dependent Activation of Cholangiocyte VEGF-a Expression Gastroenterology. 134: A-777. DOI: 10.1016/S0016-5085(08)63630-6  0.565
2008 Venter J, Glaser S, Wise C, Francis H, Vaculin BT, Kopriva S, Savage J, Alpini G. S1589 Castration Reduces Cholangiocyte Hyperplasia and Secretin-Stimulated Ductal Secretion of Bile Duct Ligated (BDL) Rats By Downregulation of the cAMP-Dependent ERK1/2 Pathway Gastroenterology. 134: A-777. DOI: 10.1016/S0016-5085(08)63629-X  0.528
2008 Yang L, Jung Y, Huang J, Omenetti A, Witek RP, Choi SS, Alpini G, Diehl AM. 685 Glial Fibrillary Acidic Protein(+) Progenitors Regenerate Adult Livers Gastroenterology. 134: A-768-A-769. DOI: 10.1016/S0016-5085(08)63589-1  0.333
2007 Xia X, Demorrow S, Francis H, Glaser S, Alpini G, Marzioni M, Fava G, Lesage G. Cholangiocyte injury and ductopenic syndromes. Seminars in Liver Disease. 27: 401-12. PMID 17979076 DOI: 10.1055/S-2007-991516  0.506
2007 Fava G, Marzioni M, Francis H, Glaser S, Demorrrow S, Ueno Y, Benedetti A, Alpini G. Novel interaction of bile acid and neural signaling in the regulation of cholangiocyte function. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 37: S420-9. PMID 17931197 DOI: 10.1111/J.1872-034X.2007.00228.X  0.586
2007 Taffetani S, Glaser S, Francis H, DeMorrow S, Ueno Y, Alvaro D, Marucci L, Marzioni M, Fava G, Venter J, Vaculin S, Vaculin B, Lam IP, Lee VH, Gaudio E, ... ... Alpini G, et al. Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms. Bmc Physiology. 7: 6. PMID 17640386 DOI: 10.1186/1472-6793-7-6  0.527
2007 Francis H, LeSage G, DeMorrow S, Alvaro D, Ueno Y, Venter J, Glaser S, Mancino MG, Marucci L, Benedetti A, Alpini G. The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats. American Journal of Physiology. Cell Physiology. 293: C1252-62. PMID 17634418 DOI: 10.1152/Ajpcell.00031.2007  0.553
2007 Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Venter J, Rychlicki C, Fava G, Francis H, Trozzi L, Glaser S, Benedetti A. Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis. Gastroenterology. 133: 244-55. PMID 17631146 DOI: 10.1053/J.Gastro.2007.04.007  0.497
2007 Glaser SS, Ueno Y, DeMorrow S, Chiasson VL, Katki KA, Venter J, Francis HL, Dickerson IM, DiPette DJ, Supowit SC, Alpini GD. Knockout of alpha-calcitonin gene-related peptide reduces cholangiocyte proliferation in bile duct ligated mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 914-26. PMID 17618297 DOI: 10.1038/Labinvest.3700602  0.496
2007 Ueno Y, Francis H, Glaser S, Demorrow S, Venter J, Benedetti A, Fava G, Marzioni M, Alpini G. Taurocholic acid feeding prevents tumor necrosis factor-alpha-induced damage of cholangiocytes by a PI3K-mediated pathway. Experimental Biology and Medicine (Maywood, N.J.). 232: 942-9. PMID 17609511  0.508
2007 Salunga TL, Cui ZG, Shimoda S, Zheng HC, Nomoto K, Kondo T, Takano Y, Selmi C, Alpini G, Gershwin ME, Tsuneyama K. Oxidative stress-induced apoptosis of bile duct cells in primary biliary cirrhosis. Journal of Autoimmunity. 29: 78-86. PMID 17544621 DOI: 10.1016/J.Jaut.2007.04.002  0.358
2007 Metalli VD, Mancino MG, Mancino A, Torrice A, Gatto M, Attili AF, Alpini G, Alvaro D. Bile salts regulate proliferation and apoptosis of liver cells by modulating the IGF1 system. Digestive and Liver Disease. 39: 654-662. PMID 17531559 DOI: 10.1016/J.Dld.2007.03.008  0.34
2007 Marzioni M, Ueno Y, Glaser S, Francis H, Benedetti A, Alvaro D, Venter J, Fava G, Alpini G. Cytoprotective effects of taurocholic acid feeding on the biliary tree after adrenergic denervation of the liver. Liver International : Official Journal of the International Association For the Study of the Liver. 27: 558-68. PMID 17403196 DOI: 10.1111/J.1478-3231.2007.01443.X  0.586
2007 Francis H, Franchitto A, Ueno Y, Glaser S, DeMorrow S, Venter J, Gaudio E, Alvaro D, Fava G, Marzioni M, Vaculin B, Alpini G. H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 473-87. PMID 17334413 DOI: 10.1038/Labinvest.3700533  0.572
2007 DeMorrow S, Glaser S, Francis H, Venter J, Vaculin B, Vaculin S, Alpini G. Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. The Journal of Biological Chemistry. 282: 13098-113. PMID 17329257 DOI: 10.1074/Jbc.M608238200  0.512
2007 Marzioni M, Baroni GS, Alpini G, Benedetti A. Endogenous opioid peptides and chronic liver disease: from bedside to bench. Journal of Hepatology. 46: 583-586. PMID 17313989 DOI: 10.1016/J.Jhep.2007.01.006  0.308
2007 Alvaro D, Mancino MG, Glaser S, Gaudio E, Marzioni M, Francis H, Alpini G. Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver. Gastroenterology. 132: 415-31. PMID 17241889 DOI: 10.1053/J.Gastro.2006.07.023  0.619
2007 Fava G, Ueno Y, Glaser S, Francis H, Demorrow S, Marucci L, Marzioni M, Benedetti A, Venter J, Vaculin B, Vaculin S, Alpini G. Thyroid hormone inhibits biliary growth in bile duct-ligated rats by PLC/IP(3)/Ca(2+)-dependent downregulation of SRC/ERK1/2. American Journal of Physiology. Cell Physiology. 292: C1467-75. PMID 17192280 DOI: 10.1152/Ajpcell.00575.2006  0.54
2007 Fava G, Marzioni M, Benedetti A, Glaser S, DeMorrow S, Francis H, Alpini G. Molecular pathology of biliary tract cancers. Cancer Letters. 250: 155-67. PMID 17069969 DOI: 10.1016/J.Canlet.2006.09.011  0.486
2007 Sario AD, Bendia E, Omenetti A, Minicis SD, Marzioni M, Kleemann HW, Candelaresi C, Saccomanno S, Alpini G, Benedetti A. Selective inhibition of ion transport mechanisms regulating intracellular pH reduces proliferation and induces apoptosis in cholangiocarcinoma cells Digestive and Liver Disease. 39: 60-69. PMID 16982221 DOI: 10.1016/J.Dld.2006.07.013  0.306
2007 Ueno Y, Francis H, Glaser S, DeMorrow S, Venter J, Benedetti A, Fava G, Marzioni M, Alpini G. Taurocholic Acid Feeding Prevents Tumor Necrosis Factor-α–Induced Damage of Cholangiocytes by a PI3K–Mediated Pathway Experimental Biology and Medicine. 232: 942-949. DOI: 10.3181/00379727-232-2320942  0.552
2006 Alvaro D, Barbaro B, Franchitto A, Onori P, Glaser SS, Alpini G, Francis H, Marucci L, Sterpetti P, Ginanni-Corradini S, Onetti Muda A, Dostal DE, De Santis A, Attili AF, Benedetti A, et al. Estrogens and insulin-like growth factor 1 modulate neoplastic cell growth in human cholangiocarcinoma. The American Journal of Pathology. 169: 877-88. PMID 16936263 DOI: 10.2353/Ajpath.2006.050464  0.507
2006 Xia X, Francis H, Glaser S, Alpini G, LeSage G. Bile acid interactions with cholangiocytes. World Journal of Gastroenterology : Wjg. 12: 3553-63. PMID 16773712 DOI: 10.3748/Wjg.V12.I22.3553  0.525
2006 Gaudio E, Franchitto A, Pannarale L, Carpino G, Alpini G, Francis H, Glaser S, Alvaro D, Onori P. Cholangiocytes and blood supply. World Journal of Gastroenterology : Wjg. 12: 3546-52. PMID 16773711 DOI: 10.3748/Wjg.V12.I22.3546  0.54
2006 Alvaro D, Mancino MG, Onori P, Franchitto A, Alpini G, Francis H, Glaser S, Gaudio E. Estrogens and the pathophysiology of the biliary tree. World Journal of Gastroenterology : Wjg. 12: 3537-45. PMID 16773710 DOI: 10.3748/Wjg.V12.I22.3537  0.531
2006 Glaser S, Francis H, Demorrow S, Lesage G, Fava G, Marzioni M, Venter J, Alpini G. Heterogeneity of the intrahepatic biliary epithelium. World Journal of Gastroenterology : Wjg. 12: 3523-36. PMID 16773709 DOI: 10.3748/Wjg.V12.I22.3523  0.588
2006 Marzioni M, Alpini G, Saccomanno S, de Minicis S, Glaser S, Francis H, Trozzi L, Venter J, Orlando F, Fava G, Candelaresi C, Macarri G, Benedetti A. Endogenous opioids modulate the growth of the biliary tree in the course of cholestasis. Gastroenterology. 130: 1831-47. PMID 16697745 DOI: 10.1053/J.Gastro.2006.02.021  0.513
2006 Gaudio E, Barbaro B, Alvaro D, Glaser S, Francis H, Ueno Y, Meininger CJ, Franchitto A, Onori P, Marzioni M, Taffetani S, Fava G, Stoica G, Venter J, Reichenbach R, ... ... Alpini G, et al. Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. Gastroenterology. 130: 1270-82. PMID 16618418 DOI: 10.1053/J.Gastro.2005.12.034  0.499
2006 Gaudio E, Barbaro B, Alvaro D, Glaser S, Francis H, Franchitto A, Onori P, Ueno Y, Marzioni M, Fava G, Venter J, Reichenbach R, Summers R, Alpini G. Administration of r-VEGF-A prevents hepatic artery ligation-induced bile duct damage in bile duct ligated rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G307-17. PMID 16574985 DOI: 10.1152/Ajpgi.00507.2005  0.58
2006 Svegliati-Baroni G, Ghiselli R, Marzioni M, Alvaro D, Mocchegiani F, Saccomanno S, Sisti V, Ugili L, Orlando F, Alpini G, Saba V, Benedetti A. Estrogens maintain bile duct mass and reduce apoptosis after biliodigestive anastomosis in bile duct ligated rats. Journal of Hepatology. 44: 1158-1166. PMID 16481066 DOI: 10.1016/J.Jhep.2005.10.032  0.35
2006 Marzioni M, Francis H, Benedetti A, Ueno Y, Fava G, Venter J, Reichenbach R, Mancino MG, Summers R, Alpini G, Glaser S. Ca2+-dependent cytoprotective effects of ursodeoxycholic and tauroursodeoxycholic acid on the biliary epithelium in a rat model of cholestasis and loss of bile ducts. The American Journal of Pathology. 168: 398-409. PMID 16436655 DOI: 10.2353/Ajpath.2006.050126  0.547
2006 Glaser S, Alvaro D, Francis H, Ueno Y, Marucci L, Benedetti A, De Morrow S, Marzioni M, Mancino MG, Phinizy JL, Reichenbach R, Fava G, Summers R, Venter J, Alpini G. Adrenergic receptor agonists prevent bile duct injury induced by adrenergic denervation by increased cAMP levels and activation of Akt. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G813-26. PMID 16339297 DOI: 10.1152/Ajpgi.00306.2005  0.536
2006 Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Glaser S, Rychlicki C, Francis H, Trozzi L, Venter J, Reichenbach R, Benedetti A. Glucagon-like peptide-1 (GLP-1) and its analogue exendin-4 promote the growth of the biliary tree Digestive and Liver Disease. 38: S33. DOI: 10.1016/S1590-8658(06)80085-X  0.383
2006 Fava G, Alpini G, Rychlicki C, Svegliati-Baroni G, Di Sario A, De Morrow S, Francis H, Venter J, Glaser S, Reichenbach R, Benedetti A. Leptin mediates a proliferative response in human cholangiocarcinoma Digestive and Liver Disease. 38: S4. DOI: 10.1016/S1590-8658(06)80008-3  0.385
2006 Fava G, Alpini G, Rychlicki C, Svegliati-Baroni G, di Sario A, De Morrow S, Francise H, Venter J, Glaser S, Reichenbach R, Benedetti A. 309 Human cholangiocarcinoma cells express leptin receptors and respond to leptin with increase of proliferation Journal of Hepatology. 44: S120. DOI: 10.1016/S0168-8278(06)80310-7  0.448
2006 Marzioni M, Alpini G, Saccomanno S, Candelaresi C, Glaser S, Rychlicki C, Francis H, Trozzi L, Venter J, Reichenbach R, Benedetti A. 97 Glucagon-like peptide-1 (GLP-1) promotes the growth of the biliary tree in the normal and in the cholestatic rat Journal of Hepatology. 44: S43. DOI: 10.1016/S0168-8278(06)80098-X  0.417
2005 Fava G, Marucci L, Glaser S, Francis H, De Morrow S, Benedetti A, Alvaro D, Venter J, Meininger C, Patel T, Taffetani S, Marzioni M, Summers R, Reichenbach R, Alpini G. gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway. Cancer Research. 65: 11437-46. PMID 16357152 DOI: 10.1158/0008-5472.Can-05-1470  0.492
2005 Fava G, Glaser S, Francis H, Alpini G. The immunophysiology of biliary epithelium. Seminars in Liver Disease. 25: 251-64. PMID 16143942 DOI: 10.1055/S-2005-916318  0.512
2005 Alvaro D, Metalli VD, Alpini G, Onori P, Franchitto A, Barbaro B, Glaser SS, Francis H, Cantafora A, Blotta I, Attili AF, Gaudio E. The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis. Journal of Hepatology. 43: 875-83. PMID 16083987 DOI: 10.1016/J.Jhep.2005.04.011  0.485
2005 Taffetani S, Ueno Y, Meng F, Venter J, Francis H, Glaser S, Alpini G, Patel T. Tannic acid inhibits cholangiocyte proliferation after bile duct ligation via a cyclic adenosine 5',3'-monophosphate-dependent pathway. The American Journal of Pathology. 166: 1671-9. PMID 15920152 DOI: 10.1016/S0002-9440(10)62477-7  0.523
2005 Alpini G, Glaser S, Baiocchi L, Francis H, Xia X, Lesage G. Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats. Hepatology (Baltimore, Md.). 41: 1037-45. PMID 15834929 DOI: 10.1002/Hep.20653  0.523
2005 Marzioni M, Glaser S, Francis H, Marucci L, Benedetti A, Alvaro D, Taffetani S, Ueno Y, Roskams T, Phinizy JL, Venter J, Fava G, Lesage GD, Alpini G. Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin. Gastroenterology. 128: 121-37. PMID 15633129 DOI: 10.1053/J.Gastro.2004.10.002  0.571
2004 LeSage GD, Alvaro D, Glaser S, Francis H, Marucci L, Roskams T, Phinizy JL, Marzioni M, Benedetti A, Taffetani S, Barbaro B, Fava G, Ueno Y, Alpini G. Alpha-1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca(2+)- and PKC-dependent stimulation of cAMP. Hepatology (Baltimore, Md.). 40: 1116-27. PMID 15486932 DOI: 10.1002/Hep.20424  0.535
2004 Gigliozzi A, Alpini G, Baroni GS, Marucci L, Metalli VD, Glaser SS, Francis H, Mancino MG, Ueno Y, Barbaro B, Benedetti A, Attili AF, Alvaro D. Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis. Gastroenterology. 127: 1198-209. PMID 15480997 DOI: 10.1053/J.Gastro.2004.06.023  0.489
2004 Francis H, Glaser S, Ueno Y, Lesage G, Marucci L, Benedetti A, Taffetani S, Marzioni M, Alvaro D, Venter J, Reichenbach R, Fava G, Phinizy JL, Alpini G. cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway. Journal of Hepatology. 41: 528-37. PMID 15464232 DOI: 10.1016/J.Jhep.2004.06.009  0.528
2004 Ueno Y, Alpini G, Yahagi K, Kanno N, Moritoki Y, Fukushima K, Glaser S, LeSage G, Shimosegawa T. Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice. Liver International : Official Journal of the International Association For the Study of the Liver. 23: 449-59. PMID 14986819 DOI: 10.1111/J.1478-3231.2003.00876.X  0.49
2004 Alpini G, Kanno N, Phinizy JL, Glaser S, Francis H, Taffetani S, LeSage G. Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G973-82. PMID 14701718 DOI: 10.1152/Ajpgi.00270.2003  0.501
2004 LeSage GD, Glaser SS, Francis H, Phinizy JL, Alpini G. 2. Functional Heterogeneity Of Intrahepatic Cholangiocytes Principles of Medical Biology. 15: 21-48. DOI: 10.1016/S1569-2582(04)15002-2  0.571
2003 Glaser S, Alvaro D, Ueno Y, Francis H, Marzioni M, Phinizy JL, Baumann B, Mancino MG, Venter J, LeSage G, Alpini G. Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+- dependent PKC isoforms. Liver International : Official Journal of the International Association For the Study of the Liver. 23: 78-88. PMID 12698962 DOI: 10.1034/J.1600-0676.2003.00814.X  0.547
2003 Marzioni M, LeSage GD, Glaser S, Patel T, Marienfeld C, Ueno Y, Francis H, Alvaro D, Tadlock L, Benedetti A, Marucci L, Baiocchi L, Phinizy JL, Alpini G. Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G837-52. PMID 12684215 DOI: 10.1152/Ajpgi.00398.2002  0.553
2003 Alpini G, Ueno Y, Tadlock L, Glaser SS, LeSage G, Francis H, Taffetani S, Marzioni M, Alvaro D, Patel T. Increased susceptibility of cholangiocytes to tumor necrosis factor-alpha cytotoxicity after bile duct ligation. American Journal of Physiology. Cell Physiology. 285: C183-94. PMID 12637265 DOI: 10.1152/Ajpcell.00497.2002  0.51
2003 Baiocchi L, Alpini G, Glaser S, Angelico M, Alvaro D, Francis H, Marzioni M, Phinizy JL, Barbaro B, LeSage G. Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. Journal of Hepatology. 38: 136-47. PMID 12547401 DOI: 10.1016/S0168-8278(02)00358-6  0.534
2003 Alpini G, Phinizy JL, Glaser S, Francis H, Benedetti A, Marucci L, LeSage G. Development and characterization of secretin-stimulated secretion of cultured rat cholangiocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G1066-73. PMID 12540366 DOI: 10.1152/Ajpgi.00260.2002  0.538
2003 Glaser S, Alvaro D, Roskams T, Phinizy JL, Stoica G, Francis H, Ueno Y, Barbaro B, Marzioni M, Mauldin J, Rashid S, Mancino MG, LeSage G, Alpini G. Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G683-94. PMID 12505882 DOI: 10.1152/Ajpgi.00302.2002  0.514
2003 Marucci L, Alpini G, Glaser SS, Alvaro D, Benedetti A, Francis H, Phinizy JL, Marzioni M, Mauldin J, Venter J, Baumann B, Ugili L, LeSage G. Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through PI3-kinase-dependent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G290-301. PMID 12388182 DOI: 10.1152/Ajpgi.00245.2002  0.538
2003 Marzioni M, Alpini G, Marucci L, Baumarun B, Francis H, Glaser S, Di Sario A, Benedetti A. 28 Activation of serotonin receptor 5-HT1A and 5-HT1B subtypes inhibits cholangiocyte proliferation and secretion of dile duct ligated (BDL) rats in a cAMP/PKA/SRC/ERK1/2 dependent manner Digestive and Liver Disease. 35: A17. DOI: 10.1016/S1590-8658(03)90059-4  0.536
2003 MELERO S, STRAZZABOSCO M, SPIRLI C, FIOROTTO R, GLASER S, FRANCIS H, ALPINI G. 1103 Expression and regulation of adenylyl cyclase isoforms (ACS) in rat cholangiocytes; effects of lipopolysaccaride (LPS) and α-napthylisothiocyanate (ANIT) treatment Hepatology. 38: 687-687. DOI: 10.1016/S0270-9139(03)81141-2  0.48
2003 TAFFETANI S, ALPINI G, FRANCIS H, GLASER S, PHINIZY J, VENTER J, BAUMANN B, PATEL T. 1099 Tannic acid inhibits cholangiocyte proliferation in bile duct ligated rats by a SRC dependent pathway Hepatology. 38: 685-685. DOI: 10.1016/S0270-9139(03)81137-0  0.532
2003 TAFFETANI S, FRANCIS H, GLASER S, PHINIZY J, MARUCCI L, BENEDETTI A, BAUMANN B, REICHENBACH R, VENTER J, ALPINI G. 1096 The pituitary hormone, prolactin stimulates normal cholangiocyte proliferation by a Ca and PKC mediated mechanism Hepatology. 38: 684-684. DOI: 10.1016/S0270-9139(03)81134-5  0.479
2003 FRANCIS H, GLASER S, TAFFETANI S, VENTER J, PHINIZY J, BAUMANN B, FAVA G, REICHENBACH R, ALPINI G. 1095 Histamine stimulates proliferation of normal cholangiocytes by Ca/PKC-dependent modulation of the cAMP-dependent PKA/SRC/MEK/ERK1/2 pathway Hepatology. 38: 683-683. DOI: 10.1016/S0270-9139(03)81133-3  0.478
2003 FAVA G, PHINIZY J, GLASER S, FRANCIS H, MARUCCI L, BENEDETTI A, BAUMANN B, TAFFETANI S, VENTER J, ALPINI G. 1090 Gamma-aminobutyric acid (GABA) inhibits cholangiocarcinoma growth by cAMP-dependent inhibition of the PkA/SRC/MEK/ERK1/2 pathway Hepatology. 38: 680-680. DOI: 10.1016/S0270-9139(03)81128-X  0.468
2003 Taffetani S, Patel T, Ueno Y, Venter J, Francis H, Baumann B, Glaser S, Marienfeld C, Phinizy JL, Marzioni M, Benedetti A, Alpini G. Taurocholate prevents TNF-α-induced bile duct damage of bile duct ligated (BDL) rats by Ca2+-and PKC-dependent mediated mechanisms Gastroenterology. 124: A729. DOI: 10.1016/S0016-5085(03)83683-1  0.516
2003 Marzioni M, Glaser S, Francis H, Ueno Y, Taffetani S, Benedetti A, Venter J, Phinizy JL, Baumann B, Alpini G. In vivo administration of an intracellular Ca2+ chelator and a PKC inhibitor to bile duct ligated (BDL), vagotomized rats abolishes the protective effects of ursodeoxycholate (UDCA) and tauroursodeoxycholate (TUDCA) against vagotomy-induced duct damage Gastroenterology. 124: A728. DOI: 10.1016/S0016-5085(03)83680-6  0.516
2003 Marzioni M, Glaser S, Francis H, Marucci L, Benedetti A, Ueno Y, Venter J, Baumann B, Phinizy JL, Alpini G. The blockage of endogenous cholangiocyte serotonin secretion enhances the growth of the biliary tree after bile duct ligation (BDL): Evidence for autocrine regulation of cholangiocyte proliferation Gastroenterology. 124: A693. DOI: 10.1016/S0016-5085(03)83505-9  0.541
2003 Taffetani S, Marienfeld C, Alpini G, Patel T. Tannic acid inhibits cholangiocyte proliferation of bile duct ligated (BDL) rats by Ca2+- and Pkc-dependent mechanisms Gastroenterology. 124: A160. DOI: 10.1016/S0016-5085(03)80798-9  0.321
2002 Alpini G, Glaser S, Alvaro D, Ueno Y, Marzioni M, Francis H, Baiocchi L, Stati T, Barbaro B, Phinizy JL, Mauldin J, Lesage G. Bile acid depletion and repletion regulate cholangiocyte growth and secretion by a phosphatidylinositol 3-kinase-dependent pathway in rats. Gastroenterology. 123: 1226-37. PMID 12360484 DOI: 10.1053/Gast.2002.36055  0.527
2002 Marzioni M, Glaser SS, Francis H, Phinizy JL, LeSage G, Alpini G. Functional heterogeneity of cholangiocytes. Seminars in Liver Disease. 22: 227-40. PMID 12360417 DOI: 10.1055/S-2002-34501  0.54
2002 Lesage GD, Marucci L, Alvaro D, Glaser SS, Benedetti A, Marzioni M, Patel T, Francis H, Phinizy JL, Alpini G. Insulin inhibits secretin-induced ductal secretion by activation of PKC alpha and inhibition of PKA activity. Hepatology (Baltimore, Md.). 36: 641-51. PMID 12198656 DOI: 10.1053/Jhep.2002.35537  0.486
2002 Alvaro D, Alpini G, Onori P, Franchitto A, Glaser SS, Le Sage G, Folli F, Attili AF, Gaudio E. Alfa and beta estrogen receptors and the biliary tree. Molecular and Cellular Endocrinology. 193: 105-8. PMID 12161009 DOI: 10.1016/S0303-7207(02)00103-X  0.531
2002 Alvaro D, Onori P, Metalli VD, Svegliati-Baroni G, Folli F, Franchitto A, Alpini G, Mancino MG, Attili AF, Gaudio E. Intracellular pathways mediating estrogen-induced cholangiocyte proliferation in the rat. Hepatology. 36: 297-304. PMID 12143037 DOI: 10.1053/Jhep.2002.34741  0.353
2002 Alvaro D, Alpini G, Onori P, Franchitto A, Glaser S, Le Sage G, Gigliozzi A, Vetuschi A, Morini S, Attili AF, Gaudio E. Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes. Gastroenterology. 123: 336-44. PMID 12105861 DOI: 10.1053/Gast.2002.34169  0.526
2002 Kanno N, Lesage G, Phinizy JL, Glaser S, Francis H, Alpini G. Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities. Hepatology (Baltimore, Md.). 35: 1329-40. PMID 12029618 DOI: 10.1053/Jhep.2002.33330  0.515
2002 Alpini G, Baiocchi L, Glaser S, Ueno Y, Marzioni M, Francis H, Phinizy JL, Angelico M, Lesage G. Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha. Hepatology (Baltimore, Md.). 35: 1041-52. PMID 11981754 DOI: 10.1053/Jhep.2002.32712  0.553
2002 Alvaro D, Gigliozzi A, Marucci L, Alpini G, Barbaro B, Monterubbianesi R, Minetola L, Mancino MG, Medina JF, Attili AF, Benedetti A. Corticosteroids modulate the secretory processes of the rat intrahepatic biliary epithelium. Gastroenterology. 122: 1058-69. PMID 11910357 DOI: 10.1053/Gast.2002.32374  0.356
2002 Taffetani S, Marucci L, Marzioni M, Glaser S, Ugili L, Alpini G, Benedetti A. 5 OP Taurocholic acid (TC) feeding prevents vagotomy-induced cholangiocyte apoptosis through P13-kinase dependent blockage of caspases activity Digestive and Liver Disease. 34: A50. DOI: 10.1016/S1590-8658(02)90191-X  0.398
2002 Alvaro D, Alpini G, Onori P, Franchitto A, Glaser S, Le Sage G, Gigliozzi A, Attili A, Gaudio E. Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes Journal of Hepatology. 36: 140. DOI: 10.1016/S0168-8278(02)80503-7  0.486
2002 Alvaro D, Alpini G, Onori P, Franchitto A, Glaser S, Le Sage G, Gigliozzi A, Attili A, Baronigaudio GS, Metalli VD, Mancino MG, Gaudio E. Estrogens induce cholangiocyte proliferation through the activation of the ERK1/2 system and the adapter proteins Sch, and Src Journal of Hepatology. 36: 28. DOI: 10.1016/S0168-8278(02)80085-X  0.484
2001 Marzioni M, Glaser SS, Alpini G, LeSage GD. Role of apoptosis in development of primary biliary cirrhosis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 33: 531-3. PMID 11816539 DOI: 10.1016/S1590-8658(01)80102-X  0.519
2001 Alpini G, Ueno Y, Glaser SS, Marzioni M, Phinizy JL, Francis H, Lesage G. Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes. Hepatology (Baltimore, Md.). 34: 868-76. PMID 11679956 DOI: 10.1053/Jhep.2001.28884  0.554
2001 Kanno N, LeSage G, Glaser S, Alpini G. Regulation of cholangiocyte bicarbonate secretion. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G612-25. PMID 11518673 DOI: 10.1152/Ajpgi.2001.281.3.G612  0.54
2001 Lesage G, Glaser S, Ueno Y, Alvaro D, Baiocchi L, Kanno N, Phinizy JL, Francis H, Alpini G. Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G182-90. PMID 11408271 DOI: 10.1152/Ajpgi.2001.281.1.G182  0.521
2001 LeSage G, Glaser S, Alpini G. Regulation of cholangiocyte proliferation. Liver. 21: 73-80. PMID 11318975 DOI: 10.1034/J.1600-0676.2001.021002073.X  0.551
2001 Kanno N, Glaser S, Chowdhury U, Phinizy JL, Baiocchi L, Francis H, LeSage G, Alpini G. Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-alpha. Journal of Hepatology. 34: 284-91. PMID 11281558 DOI: 10.1016/S0168-8278(00)00025-8  0.495
2001 McGill JM, Yen MS, Cummings OW, Alpini G, LeSage G, Pollok KE, Miller B, Engle SK, Stansfield AP. Interleukin-5 inhibition of biliary cell chloride currents and bile flow. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G738-45. PMID 11254501 DOI: 10.1152/Ajpgi.2001.280.4.G738  0.391
2001 LeSage G, Glaser S, Alpini G. Regulatory mechanisms of ductal bile secretion. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 32: 563-6. PMID 11142552 DOI: 10.1016/S1590-8658(00)80836-1  0.502
2001 Alvaro D, Alpini G, Onori P, Perego L, Svegliata Baroni G, Franchitto A, Baiocchi L, Glaser SS, Le Sage G, Folli F, Gaudio E. Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats. Gastroenterology. 119: 1681-91. PMID 11113090 DOI: 10.1053/Gast.2000.20184  0.529
2001 Ridolfi F, Alvam D, Svegliati-Baroni G, Alpini G, Onori P, Glaser S, Folli F, LeSage G, Franchitto A, Attili A, Gaudio E. Estrogens stimulate cholangiocyte proliferation through the activation of the ERK1/2 system and the adapter protein Sch Digestive and Liver Disease. 33: A16. DOI: 10.1016/S1590-8658(01)80218-8  0.407
2001 Alpini G, Tadlock L, Glaser S, Lesage G, Patel T. Increassed susceptibility of rat cholangiocytes to tumor necrosis factor α (TNFα) cytotoxicity following bile duct ligation Gastroenterology. 120: A362. DOI: 10.1016/S0016-5085(08)81802-1  0.485
2001 Lesage G, Glaser S, Francis H, Ludvik M, Phinizy JL, Kanno N, Alpini G. Alpha-napthylisothiocyanate-induced cholangiocyte apoptosis is dependent on increased reactive oxygen species (ROS) Gastroenterology. 120: A356. DOI: 10.1016/S0016-5085(08)81767-2  0.44
2001 Kanno N, Lesage G, Glaser S, Phinizy JL, Ludvik M, Alpini G. The growth of two human cholangiocarcinoma cell lines is inhibited by alpha-2 adrenergic agonists by a cAMP-dependent mechanism through the inhibition of Raf-1 and MAPK systems Gastroenterology. 120: A92. DOI: 10.1016/S0016-5085(08)80451-9  0.497
2001 Alpini G, Glaser S, Phinizy JL, Kanno N, Francis H, Ludvik M, Lesage G. Regulation of cholanglocyte apical bile acid transporter (ABAT) activity by biliary bile acids: Different potential compensatory changes for intrahepatic and extrahepatic cholestasis Gastroenterology. 120: A2. DOI: 10.1016/S0016-5085(08)80008-X  0.47
2001 Alpini G, Glaser S, Phinizy JL, Kanno N, Francis H, Ludvik M, Lesage G. Bile acid stimulation of small bile duct proliferation requires de novo expression of the apical bile acid transporter (ABAT) Gastroenterology. 120: A1. DOI: 10.1016/S0016-5085(08)80006-6  0.505
2000 Alvaro D, Benedetti A, Marucci L, Delle Monache M, Monterubbianesi R, Di Cosimo E, Perego L, Macarri G, Glaser S, Le Sage G, Alpini G. The function of alkaline phosphatase in the liver: regulation of intrahepatic biliary epithelium secretory activities in the rat. Hepatology (Baltimore, Md.). 32: 174-84. PMID 10915721 DOI: 10.1053/Jhep.2000.9078  0.548
2000 Glaser S, Benedetti A, Marucci L, Alvaro D, Baiocchi L, Kanno N, Caligiuri A, Phinizy JL, Chowdury U, Papa E, LeSage G, Alpini G. Gastrin inhibits cholangiocyte growth in bile duct-ligated rats by interaction with cholecystokinin-B/Gastrin receptors via D-myo-inositol 1,4,5-triphosphate-, Ca(2+)-, and protein kinase C alpha-dependent mechanisms. Hepatology (Baltimore, Md.). 32: 17-25. PMID 10869284 DOI: 10.1053/Jhep.2000.8265  0.526
2000 Kanno N, LeSage G, Glaser S, Alvaro D, Alpini G. Functional heterogeneity of the intrahepatic biliary epithelium. Hepatology (Baltimore, Md.). 31: 555-61. PMID 10706542 DOI: 10.1002/Hep.510310302  0.477
2000 Phinizy JL, Glaser S, Francis H, Kanno N, Chowdhury U, Alpini G, LeSage G. Development and characterization of secretory functions of a rat cholangiocyte cell culture system Gastroenterology. 118: A931. DOI: 10.1016/S0016-5085(00)85861-8  0.489
2000 Alpini G, Glaser S, Phinizy JL, Hofmann AF, LeSage G. Bile acid absorption in isolated bile duct units (IBDU) is primarily due to the apical bile acid transporter Gastroenterology. 118: A930. DOI: 10.1016/S0016-5085(00)85859-X  0.472
2000 Kanno N, Glaser S, Chowdhury U, Phinizy JL, Francis H, LeSage G, Alpini G. The alpha-2 adrenergic agonist, UK 14,304, inhibits growth andincreases apoptosis of the cholangio-carcinoma cell line, Mz-Cha-1, through camp but not Ca2+-dependent mechanisms Gastroenterology. 118: A930. DOI: 10.1016/S0016-5085(00)85858-8  0.483
2000 LeSage G, Glaser S, Alvaro D, Kanno N, Phinizy JL, Chowdury U, Alpini G. Camp stimulates secretory and proliferative capacity of the rat intrahepatic biliary epithelium through the PKA system Gastroenterology. 118: A929. DOI: 10.1016/S0016-5085(00)85856-4  0.508
2000 Kanno N, Glaser S, Phinizy JL, Chowdhury U, Francis H, Alpini G, LeSage G. Inhibition of cholangiocarcinoma growth by tauroursodeoxycholic acid requires activation of cah2+ and protein kinase c (PKC) signaling pathways Gastroenterology. 118: A906. DOI: 10.1016/S0016-5085(00)85760-1  0.483
1999 LeSage GD, Glaser SS, Marucci L, Benedetti A, Phinizy JL, Rodgers R, Caligiuri A, Papa E, Tretjak Z, Jezequel AM, Holcomb LA, Alpini G. Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 276: G1289-G1301. PMID 29591742 DOI: 10.1152/ajpgi.1999.276.5.G1289  0.476
1999 Baiocchi L, LeSage G, Glaser S, Alpini G. Regulation of cholangiocyte bile secretion. Journal of Hepatology. 31: 179-91. PMID 10424300 DOI: 10.1016/S0168-8278(99)80180-9  0.583
1999 Grappone C, Pinzani M, Parola M, Pellegrini G, Caligiuri A, Defranco R, Marra F, Herbst H, Alpini G, Milani S. Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats Journal of Hepatology. 31: 100-109. PMID 10424289 DOI: 10.1016/S0168-8278(99)80169-X  0.423
1999 Ott M, Rajvanshi P, Sokhi RP, Alpini G, Aragona E, Dabeva M, Shafritz DA, Gupta S. Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver The Journal of Pathology. 187: 365-373. PMID 10398093 DOI: 10.1002/(Sici)1096-9896(199902)187:3<365::Aid-Path237>3.0.Co;2-Z  0.395
1999 LeSagE G, Alvaro D, Benedetti A, Glaser S, Marucci L, Baiocchi L, Eisel W, Caligiuri A, Phinizy JL, Rodgers R, Francis H, Alpini G. Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats. Gastroenterology. 117: 191-9. PMID 10381927 DOI: 10.1016/S0016-5085(99)70567-6  0.54
1999 Lesage GD, Glaser SS, Marucci L, Benedetti A, Phinizy JL, Rodgers R, Caligiuri A, Papa E, Tretjak Z, Jezequel AM, Holcomb LA, Alpini G. Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 276: G1289-G1301. PMID 10330021 DOI: 10.1152/Ajpgi.1999.276.5.G1289  0.543
1999 LeSage GD, Benedetti A, Glaser S, Marucci L, Tretjak Z, Caligiuri A, Rodgers R, Phinizy JL, Baiocchi L, Francis H, Lasater J, Ugili L, Alpini G. Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver. Hepatology (Baltimore, Md.). 29: 307-19. PMID 9918904 DOI: 10.1002/Hep.510290242  0.587
1999 Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiocchi L, Holcomb LA, Caligiuri A, LeSage GD. Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion. Gastroenterology. 116: 179-86. PMID 9869616 DOI: 10.1016/S0016-5085(99)70242-8  0.535
1998 Caligiuri A, Glaser S, Rodgers RE, Phinizy JL, Robertson W, Papa E, Pinzani M, Alpini G. Endothelin-1 inhibits secretin-stimulated ductal secretion by interacting with ETreceptors on large cholangiocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G835-G846. PMID 29591802 DOI: 10.1152/Ajpgi.1998.275.4.G835  0.525
1998 Alpini G, Glaser SS, Ueno Y, Pham L, Podila PV, Caligiuri A, LeSage G, LaRusso NF. Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G767-G775. PMID 29585280 DOI: 10.1152/ajpgi.1998.274.4.G767  0.504
1998 Alpini G, Glaser SS, Ueno Y, Pham L, Podila PV, Caligiuri A, LeSage G, LaRusso NF. Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation. The American Journal of Physiology. 274: G767-75. PMID 9575860 DOI: 10.1152/Ajpgi.1998.274.4.G767  0.544
1998 LeSage G, Glaser S, Caligiuri A, Phinizy J, Rodgers R, Francis H, Papa E, Lasater J, Robertson W, Alpini G. Insulin inhibits secretin-stimulated ductal bile secretion in bile duct-ligated (BDL) rats by interaction with insulin receptors on cholangiocytes Gastroenterology. 114: A1287. DOI: 10.1016/S0016-5085(98)85225-6  0.422
1998 Alvaro D, Alpini G, Glaser S, Papa E, Onori P, Franchitto A, Gigliozzi A, Caligiuri A, LeSage G, Gaudio E. Estrogen receptors are expressed in rat cholangiocytes and upregulated after bile duct ligation: Their inhibition with chronic tamoxifen treatment markedly decreases secretin-induced ductal bile secretion Gastroenterology. 114: A1202-A1203. DOI: 10.1016/S0016-5085(98)84880-4  0.496
1998 Alvaro D, Benedetti A, Glaser S, Caligiuri A, Marucci L, Papa E, Gigliozzi A, Fraioli F, Phinizy J, LeSage G, Alpini G. Alkaline phosphate regulates secretory processes in rat intrahepatic biliary epithelium Gastroenterology. 114: A1202. DOI: 10.1016/S0016-5085(98)84879-8  0.444
1998 Alpini G, Glaser S, Caligiuri A, Phinizy J, Rodgers R, Francis H, Robertson W, Papa E, Lasater J, LeSage G. Ursodeoxycholic acid feeding inhibits secretin-induced cholangiocyte secretory processes in bile duct ligated rats Gastroenterology. 114: A1202. DOI: 10.1016/S0016-5085(98)84878-6  0.453
1997 Glaser SS, Rodgers RED, Phinizy JL, Robertson WE, Lasater J, Caligiuri A, Tretjak Z, Lesage GD, Alpini G. Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 273: G1061-G1070. PMID 29585434 DOI: 10.1152/Ajpgi.1997.273.5.G1061  0.538
1997 Alpini G, Glaser SS, Rodgers R, Phinizy JL, Robertson WE, Lasater J, Caligiuri A, Tretjak Z, LeSage GD. Functional expression of the apical Na+-dependent bile acid transporter in large but not small rat cholangiocytes. Gastroenterology. 113: 1734-40. PMID 9352879 DOI: 10.1053/Gast.1997.V113.Pm9352879  0.51
1997 Alvaro D, Alpini G, Jezequel AM, Bassotti C, Francia C, Fraioli F, Romeo R, Marucci L, Le Sage G, Glaser SS, Benedetti A. Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions. The Journal of Clinical Investigation. 100: 1349-62. PMID 9294100 DOI: 10.1172/Jci119655  0.511
1997 Alpini G, Elias I, Glaser SS, Rodgers RE, Phinizy JL, Robertson WE, Francis H, Lasater J, Richards M, LeSage GD. gamma-Interferon inhibits secretin-induced choleresis and cholangiocyte proliferation in a murine model of cirrhosis. Journal of Hepatology. 27: 371-80. PMID 9288613 DOI: 10.1016/S0168-8278(97)80184-5  0.522
1997 Alpini G, Glaser S, Robertson W, Phinizy JL, Rodgers RE, Caligiuri A, LeSage G. Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes. The American Journal of Physiology. 273: G518-29. PMID 9277433 DOI: 10.1152/Ajpgi.1997.273.2.G518  0.507
1997 Alpini G, Glaser S, Robertson W, Rodgers RE, Phinizy JL, Lasater J, LeSage GD. Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion. The American Journal of Physiology. 272: G1064-74. PMID 9176215 DOI: 10.1152/Ajpgi.1997.272.5.G1064  0.537
1997 Alpini G, Ulrich C, Roberts S, Phillips JO, Ueno Y, Podila PV, Colegio O, LeSage GD, Miller LJ, LaRusso NF. Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation. The American Journal of Physiology. 272: G289-97. PMID 9124353 DOI: 10.1152/Ajpgi.1997.272.2.G289  0.401
1997 Lesage G, Glaser SS, Gubba S, Robertson WE, Phinizy JL, Lasater J, Rodgers RE, Alpini G. Regrowth of the rat biliary tree after 70% partial hepatectomy is coupled to increased secretin-induced ductal secretion. Gastroenterology. 111: 1633-44. PMID 8942744 DOI: 10.1016/S0016-5085(96)70027-6  0.575
1996 Alpini G, Roberts S, Kuntz SM, Ueno Y, Gubba S, Podila PV, LeSage G, LaRusso NF. Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver. Gastroenterology. 110: 1636-43. PMID 8613073 DOI: 10.1053/Gast.1996.V110.Pm8613073  0.384
1995 Tietz PS, Alpini G, Pham LD, Larusso NF. Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes. The American Journal of Physiology. 269: G110-8. PMID 7631787 DOI: 10.1152/Ajpgi.1995.269.1.G110  0.422
1994 Gupta S, Alpini G, Vemuru RP, Hurston E, Shafritz DA. Butyrate synchronization of hepatocytes: modulation of cycling and cell cycle regulated gene expression. Growth Factors (Chur, Switzerland). 10: 171-80. PMID 7946406 DOI: 10.3109/08977199409000235  0.352
1994 Alpini G, Ulrich CD, Phillips JO, Pham LD, Miller LJ, LaRusso NF. Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation. The American Journal of Physiology. 266: G922-8. PMID 7515577 DOI: 10.1152/Ajpgi.1994.266.5.G922  0.388
1994 Alpini G, Phillips JO, Vroman B, Larusso NF. Recent advances in the isolation of liver cells Hepatology. 20: 494-514. DOI: 10.1002/Hep.1840200231  0.354
1993 Dabeva MD, Alpini G, Hurston E, Shafritz DA. Models for hepatic progenitor cell activation Experimental Biology and Medicine. 204: 242-252. PMID 7694303 DOI: 10.3181/00379727-204-43660  0.426
1992 Lenzi R, Liu MH, Lenzen R, Han T, Alpini G, Tavoloni N. Distribution of glucose-6-phosphatase activity in normal, hyperplastic, and preneoplastic rat liver. Virchows Archiv B Cell Pathology Including Molecular Pathology. 61: 279-287. PMID 1685820 DOI: 10.1007/Bf02890429  0.427
1992 Lenzen R, Alpini G, Tavoloni N. Secretin stimulates bile ductular secretory activity through the cAMP system. American Journal of Physiology-Gastrointestinal and Liver Physiology. 263. PMID 1329554 DOI: 10.1152/Ajpgi.1992.263.4.G527  0.386
1992 Schubart UK, Xu J, Fan W, Cheng G, Goldstein H, Alpini G, Shafritz DA, Amat JA, Farooq M, Norton WT. Widespread differentiation stage-specific expression of the gene encoding phosphoprotein p19 (metablastin) in mammalian cells. Differentiation; Research in Biological Diversity. 51: 21-32. PMID 1280608 DOI: 10.1111/J.1432-0436.1992.Tb00676.X  0.36
1990 Lenzi R, Alpini G, Liu MH, Rand JH, Tavoloni N. von Willebrand factor antigen is not an accurate marker of rat and guinea pig liver endothelial cells. Liver. 10: 372-9. PMID 2074734 DOI: 10.1111/J.1600-0676.1990.Tb00483.X  0.403
1989 Alpini G, Lenzi R, Zhai WR, Slott PA, Liu MH, Sarkozi L, Tavoloni N. Bile secretory function of intrahepatic biliary epithelium in the rat. American Journal of Physiology-Gastrointestinal and Liver Physiology. 257. PMID 2750903 DOI: 10.1152/Ajpgi.1989.257.1.G124  0.424
1989 Alpini G, Lenzi R, Zhai WR, Liu MH, Slott PA, Paronetto F, Tavoloni N. Isolation of a nonparenchymal liver cell fraction enriched in cells with biliary epithelial phenotypes. Gastroenterology. 97: 1248-1260. PMID 2477298 DOI: 10.1016/0016-5085(89)91696-X  0.443
1988 Okuda H, Sorrentino D, Alpini G, Tavoloni N, Jones MJ, Kiang CL, Berk PD. Bile acid secretion and pool size during phenobarbital induced hypercholeresis. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 187: 202-8. PMID 3340628 DOI: 10.3181/00379727-187-42655  0.385
1988 Alpini G, Lenzi R, Sarkozi L, Tavoloni N. Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. Journal of Clinical Investigation. 81: 569-578. PMID 2448343 DOI: 10.1172/Jci113355  0.403
1987 Sorrentino D, Licko V, Weisiger RA, Alpini G, Berk PD. Phenobarbital specifically increases the hepatocellular uptake of sulfobromophthalein-glutathione Biochemical and Biophysical Research Communications. 149: 921-926. PMID 3426617 DOI: 10.1016/0006-291X(87)90496-7  0.385
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