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Hwayoung Yun, Ph.D. - Publications

Affiliations: 
2014- College of Pharmacy Pusan National University 
Website:
http://hyun.pusan.ac.kr/
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jo J, Kim J, Ibrahim L, Kumar M, Iaconelli J, So Tran C, Ryong Moon H, Jung Y, Luke Wiseman R, Lairson LL, Chatterjee AK, Bollong MJ, Yun H. Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators. Bioorganic & Medicinal Chemistry Letters. 129306. PMID 37116763 DOI: 10.1016/j.bmcl.2023.129306  0.777
2022 Lee SM, Kim CE, Park HY, Yoon EH, Won HJ, Ahn JM, Nguyen NZN, Kim M, Jang WH, Lee WS, Kang MS, Jeong M, Yun H, Park S, Wu S, et al. Aryl hydrocarbon receptor-targeted therapy of CD4+ T-cell-mediated idiopathic pneumonia syndrome in mice. Blood. PMID 35226727 DOI: 10.1182/blood.2021013849  0.309
2021 Song K, Rajasekaran N, Chelakkot C, Lee HS, Paek SM, Yang H, Jia L, Park HG, Son WS, Kim YJ, Choi JS, Jeong HM, Suh YG, Yun H, Shin YK. Macrosphelide A Exhibits a Specific Anti-Cancer Effect by Simultaneously Inactivating ENO1, ALDOA, and FH. Pharmaceuticals (Basel, Switzerland). 14. PMID 34681284 DOI: 10.3390/ph14101060  0.314
2021 Lee SC, Ma JSY, Kim MS, Laborda E, Choi SH, Hampton EN, Yun H, Nunez V, Muldong MT, Wu CN, Ma W, Kulidjian AA, Kane CJ, Klyushnichenko V, Woods AK, et al. A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand. Science Advances. 7. PMID 34380625 DOI: 10.1126/sciadv.abi8193  0.777
2021 Cao YJ, Wang X, Wang Z, Zhao L, Li S, Zhang Z, Wei X, Yun H, Choi SH, Liu Z, Zhao L, Kazane SA. Switchable CAR-T Cells Outperformed Traditional Antibody-Redirected Therapeutics Targeting Breast Cancers. Acs Synthetic Biology. PMID 33856201 DOI: 10.1021/acssynbio.1c00007  0.8
2021 Jo J, Ibrahim L, Iaconelli J, Kwak J, Kumar M, Jung Y, Lairson LL, Chatterjee AK, Schultz PG, Bollong MJ, Yun H. Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators. Bioorganic Chemistry. 108: 104614. PMID 33508678 DOI: 10.1016/j.bioorg.2020.104614  0.773
2019 Jo J, Kim H, Oh JY, Kim S, Park YH, Choi H, Jeong JY, Jung YS, Yun H. SAR optimization studies on a novel series of 2-anilinopyrimidines as selective inhibitors against triple-negative breast cancer cell line MDA-MB-468. Bioorganic & Medicinal Chemistry Letters. 126752. PMID 31711784 DOI: 10.1016/J.Bmcl.2019.126752  0.363
2019 Jo J, Jeong M, Ahn JS, Akter J, Kim HS, Suh YG, Yun H. Total Synthesis of Anmindenol A and Its Application to the Design, Synthesis, and Biological Evaluation of Derivatives Thereof. The Journal of Organic Chemistry. PMID 31357857 DOI: 10.1021/Acs.Joc.9B01564  0.352
2018 Jo J, Kim SH, Kim H, Jeong M, Kwak JH, Taek Han Y, Jeong JY, Jung YS, Yun H. Discovery and SAR studies of novel 2-anilinopyrimidine-based selective inhibitors against triple-negative breast cancer cell line MDA-MB-468. Bioorganic & Medicinal Chemistry Letters. PMID 30447889 DOI: 10.1016/J.Bmcl.2018.11.010  0.359
2018 Ahn SY, Jo MS, Lee D, Baek SE, Baek J, Yu JS, Jo J, Yun H, Kang KS, Yoo JE, Kim KH. Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells. Bioorganic Chemistry. 83: 135-144. PMID 30352359 DOI: 10.1016/J.Bioorg.2018.10.017  0.36
2018 Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. PMID 30323285 DOI: 10.1038/S41586-018-0622-0  0.719
2018 Jung JW, Kim NJ, Yun H, Han YT. Recent Advances in Synthesis of 4-Arylcoumarins. Molecules (Basel, Switzerland). 23. PMID 30241375 DOI: 10.3390/Molecules23102417  0.61
2017 Ahn J, Lim C, Yun H, Kim HS, Kwon S, Lee J, Lee S, An H, Park HG, Suh YG. Asymmetric Total Synthesis of (+)-Intricenyne via an Endocyclization Route to Oxocane Skeleton. Organic Letters. 19: 6642-6645. PMID 29192789 DOI: 10.1021/Acs.Orglett.7B03370  0.307
2017 Lee SM, Park HY, Suh YS, Yoon EH, Kim J, Jang WH, Lee WS, Park SG, Choi IW, Choi I, Kang SW, Yun H, Teshima T, Kwon B, Seo SK. Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 28673995 DOI: 10.1073/Pnas.1615280114  0.346
2016 Cao Y, Rodgers DT, Du J, Ahmad I, Hampton EN, Ma JS, Mazagova M, Choi SH, Yun HY, Xiao H, Yang P, Luo X, Lim RK, Pugh HM, Wang F, et al. Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer. Angewandte Chemie (International Ed. in English). 55: 7520-4. PMID 27145250 DOI: 10.1002/Anie.201601902  0.722
2016 Ma JS, Kim JY, Kazane SA, Choi SH, Yun HY, Kim MS, Rodgers DT, Pugh HM, Singer O, Sun SB, Fonslow BR, Kochenderfer JN, Wright TM, Schultz PG, Young TS, et al. Versatile strategy for controlling the specificity and activity of engineered T cells. Proceedings of the National Academy of Sciences of the United States of America. 113: E450-8. PMID 26759368 DOI: 10.1073/Pnas.1524193113  0.761
2015 Bollong MJ, Yun H, Sherwood L, Woods AK, Lairson LL, Schultz PG. A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer. Acs Chemical Biology. 10: 2193-8. PMID 26270491 DOI: 10.1021/Acschembio.5B00448  0.78
2015 Kim MS, Ma JS, Yun H, Cao Y, Kim JY, Chi V, Wang D, Woods A, Sherwood L, Caballero D, Gonzalez J, Schultz PG, Young TS, Kim CH. Redirection of genetically engineered CAR-T cells using bifunctional small molecules. Journal of the American Chemical Society. 137: 2832-5. PMID 25692571 DOI: 10.1021/Jacs.5B00106  0.805
2014 Yun H, Sim J, An H, Lee J, Lee HS, Shin YK, Paek SM, Suh YG. Design and synthesis of a macrosphelide A-biotin chimera. Organic & Biomolecular Chemistry. 12: 7127-35. PMID 25098405 DOI: 10.1039/C4Ob01028K  0.37
2014 Kim K, Maharjan S, Lim C, Kim NJ, Agrawal V, Han YT, Lee S, An H, Yun H, Choi HJ, Kwon YG, Suh YG. Glucal-conjugated sterols as novel vascular leakage blocker: structure-activity relationship focusing on the C17-side chain. European Journal of Medicinal Chemistry. 75: 184-94. PMID 24531231 DOI: 10.1016/J.Ejmech.2014.01.027  0.608
2014 Chun SK, Jang J, Chung S, Yun H, Kim NJ, Jung JW, Son GH, Suh YG, Kim K. Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock. Acs Chemical Biology. 9: 703-10. PMID 24387302 DOI: 10.1021/Cb400752K  0.625
2013 Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: 17796-801. PMID 24127589 DOI: 10.1073/Pnas.1316026110  0.762
2013 Seo H, Yun H, Lee S, Jang J, Han YT, Kim DD, Lee J, Suh YG. Stereoselective synthesis of 7-epi-incarvilline. Organic Letters. 15: 531-3. PMID 23343424 DOI: 10.1021/Ol303395F  0.315
2013 Kim NJ, Li FN, Lee JH, Park SG, Kim K, Lim C, Han YT, Yun H, Jung JW, Park HG, Kim HD, Woo BY, Shin SS, Kim SY, Choi JK, et al. Heterocycle-linked phenylbenzyl amides as novel TRPV1 antagonists and their TRPV1 binding modes: constraint-induced enhancement of in vitro and in vivo activities. Chemistry, An Asian Journal. 8: 400-9. PMID 23208797 DOI: 10.1002/Asia.201200730  0.62
2012 Chang DJ, An H, Kim KS, Kim HH, Jung J, Lee JM, Kim NJ, Han YT, Yun H, Lee S, Lee G, Lee S, Lee JS, Cha JH, Park JH, et al. Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis. Journal of Medicinal Chemistry. 55: 10863-84. PMID 23186287 DOI: 10.1021/Jm301488Q  0.651
2012 Han YT, Choi GI, Son D, Kim NJ, Yun H, Lee S, Chang DJ, Hong HS, Kim H, Ha HJ, Kim YH, Park HJ, Lee J, Suh YG. Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors. Journal of Medicinal Chemistry. 55: 9120-35. PMID 22742537 DOI: 10.1021/Jm300172Z  0.611
2012 Suh YG, Lee YS, Kim SH, Jung JK, Yun H, Jang J, Kim NJ, Jung JW. A stereo-controlled access to functionalized macrolactams via an aza-Claisen rearrangement. Organic & Biomolecular Chemistry. 10: 561-8. PMID 22108849 DOI: 10.1039/C1Ob06733H  0.596
2012 Sim J, Yun H, Jung J, Lee S, Kim N, Suh Y. Achiral auxiliary-assisted chiral transfer via microwave-accelerated aza-Claisen rearrangement: a short synthesis of (+)-1-hydroxyquinolizidinone Tetrahedron Letters. 53: 4813-4815. DOI: 10.1016/J.Tetlet.2012.06.073  0.591
2011 Han YT, Kim NJ, Jung JW, Yun H, Lee S, Suh YG. A versatile synthetic approach to grandisol monoterpene pheromone. Archives of Pharmacal Research. 34: 1437-42. PMID 21975804 DOI: 10.1007/S12272-011-0904-7  0.587
2011 Lee S, Paek SM, Yun H, Kim NJ, Suh YG. Enantioselective total synthesis of a natural iridoid. Organic Letters. 13: 3344-7. PMID 21619009 DOI: 10.1021/Ol201089F  0.595
2010 Kim NJ, Moon H, Park T, Yun H, Jung JW, Chang DJ, Kim DD, Suh YG. Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2). The Journal of Organic Chemistry. 75: 7458-60. PMID 20929274 DOI: 10.1021/Jo101523K  0.584
2009 Yun H, Paek SM, Jung JW, Kim NJ, Kim SH, Suh YG. First total syntheses of (-)-macrosphelides J and K and elucidation of their absolute configuration. Chemical Communications (Cambridge, England). 2463-5. PMID 19532857 DOI: 10.1039/B817693K  0.555
2009 Paek SM, Yun H, Kim NJ, Jung JW, Chang DJ, Lee S, Yoo J, Park HJ, Suh YG. Concise syntheses of (+)-macrosphelides A and B: studies on the macro-ring closure strategy. The Journal of Organic Chemistry. 74: 554-61. PMID 19086801 DOI: 10.1021/Jo8016692  0.596
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