| Year |
Citation |
Score |
| 2024 |
Sun Q, Wang Y, Hou L, Li S, Hong JS, Wang Q, Zhao J. Clozapine-N-oxide protects dopaminergic neurons against rotenone-induced neurotoxicity by preventing ferritinophagy-mediated ferroptosis. Free Radical Biology & Medicine. PMID 38182072 DOI: 10.1016/j.freeradbiomed.2023.12.045 |
0.389 |
|
| 2023 |
Yang JJ, Liu YX, Wang YF, Ge BY, Wang Y, Wang QS, Li S, Zhang JJ, Jin LL, Hong JS, Yin SM, Zhao J. Anti-epileptic and Neuroprotective Effects of Ultra-low Dose NADPH Oxidase Inhibitor Dextromethorphan on Kainic Acid-induced Chronic Temporal Lobe Epilepsy in Rats. Neuroscience Bulletin. PMID 37973720 DOI: 10.1007/s12264-023-01140-8 |
0.571 |
|
| 2023 |
Wang Q, Ruan Z, Jing L, Guo Z, Zhang X, Liu J, Tian L, Sun W, Song S, Hong JS, Shih YI, Hou L, Wang Q. Complement receptor 3-mediated neurotoxic glial activation contributes to rotenone-induced cognitive decline in mice. Ecotoxicology and Environmental Safety. 266: 115550. PMID 37832486 DOI: 10.1016/j.ecoenv.2023.115550 |
0.556 |
|
| 2023 |
Zhou R, Chen SH, Zhao Z, Tu D, Song S, Wang Y, Wang Q, Feng J, Hong JS. Complement C3 Enhances LPS-Elicited Neuroinflammation and Neurodegeneration Via the Mac1/NOX2 Pathway. Molecular Neurobiology. PMID 37268807 DOI: 10.1007/s12035-023-03393-w |
0.624 |
|
| 2023 |
Tu D, Velagapudi R, Gao Y, Hong JS, Zhou H, Gao HM. Activation of neuronal NADPH oxidase NOX2 promotes inflammatory neurodegeneration. Free Radical Biology & Medicine. 200: 47-58. PMID 36870375 DOI: 10.1016/j.freeradbiomed.2023.03.001 |
0.426 |
|
| 2023 |
Song S, Tu D, Meng C, Liu J, Wilson B, Wang Q, Shih YI, Gao HM, Hong JS. Dysfunction of the noradrenergic system drives inflammation, α-synucleinopathy, and neuronal loss in mouse colon. Frontiers in Immunology. 14: 1083513. PMID 36845109 DOI: 10.3389/fimmu.2023.1083513 |
0.603 |
|
| 2022 |
Yang R, Gao Y, Li H, Huang W, Tu D, Yang M, Liu X, Hong JS, Gao HM. Posttranslational S-nitrosylation modification regulates HMGB1 secretion and promotes its proinflammatory and neurodegenerative effects. Cell Reports. 40: 111330. PMID 36103834 DOI: 10.1016/j.celrep.2022.111330 |
0.356 |
|
| 2022 |
Zhang X, Tu D, Li S, Li N, Li D, Gao Y, Tian L, Liu J, Zhang X, Hong JS, Hou L, Zhao J, Wang Q. A novel synthetic peptide SVHRSP attenuates dopaminergic neurodegeneration by inhibiting NADPH oxidase-mediated neuroinflammation in experimental models of Parkinson's disease. Free Radical Biology & Medicine. PMID 35760232 DOI: 10.1016/j.freeradbiomed.2022.06.241 |
0.648 |
|
| 2022 |
Chen SH, Han S, Hu CF, Zhou R, Gao Y, Tu D, Gao H, Feng J, Wang Y, Lu RB, Hong JS. Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration. Antioxidants (Basel, Switzerland). 11. PMID 35740099 DOI: 10.3390/antiox11061202 |
0.351 |
|
| 2021 |
Hou L, Zhou X, Zhang C, Wang K, Liu X, Che Y, Sun F, Li H, Wang Q, Zhang D, Hong JS. Corrigendum to "NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease" [Redox Biol. 2017, 12: 162-170]. Redox Biology. 102119. PMID 34465554 DOI: 10.1016/j.redox.2021.102119 |
0.57 |
|
| 2021 |
Jing L, Hou L, Zhang D, Li S, Ruan Z, Zhang X, Hong JS, Wang Q. Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson's Disease Mouse Model. Journal of Inflammation Research. 14: 1341-1356. PMID 33859489 DOI: 10.2147/JIR.S299927 |
0.644 |
|
| 2021 |
Zhang D, Li S, Hou L, Jing L, Ruan Z, Peng B, Zhang X, Hong JS, Zhao J, Wang Q. Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson's disease model. Journal of Neuroinflammation. 18: 4. PMID 33402167 DOI: 10.1186/s12974-020-02065-z |
0.548 |
|
| 2020 |
Song S, Liu J, Zhang F, Hong JS. Norepinephrine depleting toxin DSP-4 and LPS alter gut microbiota and induce neurotoxicity in α-synuclein mutant mice. Scientific Reports. 10: 15054. PMID 32929122 DOI: 10.1038/S41598-020-72202-4 |
0.434 |
|
| 2020 |
Shindo S, Chen SH, Gotoh S, Yokobori K, Hu H, Ray M, Moore R, Nagata K, Martinez J, Hong JS, Negishi M. Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia. Cell Communication and Signaling : Ccs. 18: 117. PMID 32727504 DOI: 10.1186/S12964-020-00578-X |
0.341 |
|
| 2020 |
Zhao Z, Wang Y, Zhou R, Li Y, Gao Y, Tu D, Wilson B, Song S, Feng J, Hong JS, Yakel JL. A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration. Journal of Neuroinflammation. 17: 64. PMID 32070376 DOI: 10.1186/S12974-020-1728-5 |
0.329 |
|
| 2020 |
Hou L, Zhang L, Hong JS, Zhang D, Zhao J, Wang Q. NADPH oxidase and neurodegenerative diseases: mechanisms and therapy. Antioxidants & Redox Signaling. PMID 31968994 DOI: 10.1089/Ars.2019.8014 |
0.599 |
|
| 2020 |
Gao Y, Tu D, Yang R, Chu CH, Hong JS, Gao HM. Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration. International Journal of Molecular Sciences. 21. PMID 31940754 DOI: 10.3390/Ijms21020465 |
0.326 |
|
| 2020 |
Wang Q, Oyarzabal EA, Song S, Wilson B, Santos JH, Hong JS. Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration. Brain, Behavior, and Immunity. PMID 31923552 DOI: 10.1016/J.Bbi.2020.01.003 |
0.824 |
|
| 2019 |
Tu D, Gao Y, Yang R, Guan T, Hong JS, Gao HM. The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration. Journal of Neuroinflammation. 16: 255. PMID 31805953 DOI: 10.1186/S12974-019-1659-1 |
0.336 |
|
| 2019 |
Song S, Wang Q, Jiang L, Oyarzabal E, Riddick NV, Wilson B, Moy SS, Shih YI, Hong JS. Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. Brain, Behavior, and Immunity. PMID 31247288 DOI: 10.1016/J.Bbi.2019.06.034 |
0.799 |
|
| 2019 |
Zhou R, Chen SH, Li G, Chen HL, Liu Y, Wu HM, Wang Y, Feng J, Hong JS. Ultralow doses of dextromethorphan protect mice from endotoxin-induced sepsis-like hepatotoxicity. Chemico-Biological Interactions. PMID 30822415 DOI: 10.1016/J.Cbi.2019.02.025 |
0.41 |
|
| 2018 |
Li H, Song S, Wang Y, Huang C, Zhang F, Liu J, Hong JS. Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats. Neurotoxicity Research. PMID 30328585 DOI: 10.1007/S12640-018-9968-1 |
0.416 |
|
| 2018 |
Song S, Jiang L, Oyarzabal EA, Wilson B, Li Z, Shih YI, Wang Q, Hong JS. Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration. Molecular Neurobiology. PMID 30051353 DOI: 10.1007/S12035-018-1235-1 |
0.81 |
|
| 2018 |
Lai CL, Lu CC, Lin HC, Sung YF, Wu YP, Hong JS, Peng GS. Valproate is protective against 6-OHDA-induced dopaminergic neurodegeneration in rodent midbrain: A potential role of BDNF up-regulation. Journal of the Formosan Medical Association = Taiwan Yi Zhi. PMID 30031602 DOI: 10.1016/J.Jfma.2018.06.017 |
0.443 |
|
| 2018 |
Hashiguchi T, Shindo S, Chen SH, Hong JS, Negishi M. Sulfotransferase 4A1 (SULT4A1) increases its expression in mouse neurons as they mature. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29626075 DOI: 10.1124/Dmd.118.080838 |
0.408 |
|
| 2018 |
Hou L, Li Q, Jiang L, Qiu H, Geng C, Hong JS, Li H, Wang Q. Hypertension and Diagnosis of Parkinson's Disease: A Meta-Analysis of Cohort Studies. Frontiers in Neurology. 9: 162. PMID 29615961 DOI: 10.3389/Fneur.2018.00162 |
0.555 |
|
| 2018 |
Chen SH, Sung YF, Oyarzabal EA, Tan YM, Leonard J, Guo M, Li S, Wang Q, Chu CH, Chen SL, Lu RB, Hong JS. Physiological Concentration of Prostaglandin EExerts Anti-inflammatory Effects by Inhibiting Microglial Production of Superoxide Through a Novel Pathway. Molecular Neurobiology. PMID 29492849 DOI: 10.1007/S12035-018-0965-4 |
0.817 |
|
| 2018 |
Dang DK, Shin EJ, Kim DJ, Tran HQ, Jeong JH, Jang CG, Nah SY, Jeong JH, Byun JK, Ko SK, Bing G, Hong JS, Kim HC. Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor. Journal of Neuroinflammation. 15: 52. PMID 29467000 DOI: 10.1186/S12974-018-1087-7 |
0.391 |
|
| 2017 |
Dang DK, Shin EJ, Kim DJ, Tran HQ, Jeong JH, Jang CG, Ottersen OP, Nah SY, Hong JS, Nabeshima T, Kim HC. PKCδ-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity. Free Radical Biology & Medicine. PMID 29269308 DOI: 10.1016/j.freeradbiomed.2017.12.018 |
0.313 |
|
| 2017 |
Hou L, Zhou X, Zhang C, Wang K, Liu X, Che Y, Sun F, Li H, Wang Q, Zhang D, Hong JS. NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease. Redox Biology. 12: 162-170. PMID 28237879 DOI: 10.1016/J.Redox.2017.02.016 |
0.667 |
|
| 2016 |
Zhang W, Gao JH, Yan ZF, Huang XY, Guo P, Sun L, Liu Z, Hu Y, Zuo LJ, Yu SY, Cao CJ, Wang XM, Hong JS. Minimally Toxic Dose of Lipopolysaccharide and α-Synuclein Oligomer Elicit Synergistic Dopaminergic Neurodegeneration: Role and Mechanism of Microglial NOX2 Activation. Molecular Neurobiology. PMID 27975175 DOI: 10.1007/S12035-016-0308-2 |
0.477 |
|
| 2016 |
Jiang L, Wu X, Wang S, Chen SH, Zhou H, Wilson B, Jin CY, Lu RB, Xie K, Wang Q, Hong JS. Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase. Journal of Neuroinflammation. 13: 110. PMID 27184631 DOI: 10.1186/s12974-016-0573-z |
0.572 |
|
| 2016 |
Chu CH, Wang S, Li CL, Chen SH, Hu CF, Chung YL, Chen SL, Wang Q, Lu RB, Gao HM, Hong JS. Neurons and astroglia govern microglial endotoxin tolerance through macrophage colony-stimulating factor receptor-mediated ERK1/2 signals. Brain, Behavior, and Immunity. PMID 27132056 DOI: 10.1016/J.Bbi.2016.04.015 |
0.599 |
|
| 2016 |
Dang DK, Shin EJ, Nam Y, Ryoo S, Jeong JH, Jang CG, Nabeshima T, Hong JS, Kim HC. Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK. Journal of Neuroinflammation. 13: 12. PMID 26780950 DOI: 10.1186/S12974-016-0478-X |
0.398 |
|
| 2015 |
Chen SH, Oyarzabal EA, Hong JS. Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration. Current Opinion in Pharmacology. 26: 54-60. PMID 26498406 DOI: 10.1016/J.Coph.2015.10.001 |
0.765 |
|
| 2015 |
Wang Q, Oyarzabal E, Wilson B, Qian L, Hong JS. Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice. Clinical Science (London, England : 1979). 129: 757-67. PMID 26223840 DOI: 10.1042/Cs20150008 |
0.772 |
|
| 2015 |
Jiang L, Chen SH, Chu CH, Wang SJ, Oyarzabal E, Wilson B, Sanders V, Xie K, Wang Q, Hong JS. A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis. Glia. 63: 1057-72. PMID 25740080 DOI: 10.1002/Glia.22801 |
0.821 |
|
| 2015 |
Wang Q, Qian L, Chen SH, Chu CH, Wilson B, Oyarzabal E, Ali S, Robinson B, Rao D, Hong JS. Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models. Brain : a Journal of Neurology. 138: 1247-62. PMID 25716193 DOI: 10.1093/Brain/Awv034 |
0.806 |
|
| 2015 |
Nguyen XK, Lee J, Shin EJ, Dang DK, Jeong JH, Nguyen TT, Nam Y, Cho HJ, Lee JC, Park DH, Jang CG, Hong JS, Nabeshima T, Kim HC. Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene. Journal of Pineal Research. 58: 86-106. PMID 25407782 DOI: 10.1111/Jpi.12195 |
0.355 |
|
| 2015 |
Chu CH, Chen SH, Wang Q, Langenbach R, Li H, Zeldin D, Chen SL, Wang S, Gao H, Lu RB, Hong JS. PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition. Molecular Neurobiology. 52: 587-600. PMID 25218510 DOI: 10.1007/S12035-014-8889-0 |
0.541 |
|
| 2015 |
Chen SH, Oyarzabal EA, Sung YF, Chu CH, Wang Q, Chen SL, Lu RB, Hong JS. Microglial regulation of immunological and neuroprotective functions of astroglia. Glia. 63: 118-31. PMID 25130274 DOI: 10.1002/Glia.22738 |
0.807 |
|
| 2015 |
Chen SH, Oyarzabal EA, Santos J, Wang Q, Jiang L, Hong JS. Neuroinflammation in Neurological Dysfunction and Degeneration Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. 385-407. DOI: 10.1016/B978-0-12-800228-5.00018-2 |
0.692 |
|
| 2014 |
Wang Q, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12490-503. PMID 25209287 DOI: 10.1523/Jneurosci.2238-14.2014 |
0.795 |
|
| 2014 |
Wang Q, Chu CH, Oyarzabal E, Jiang L, Chen SH, Wilson B, Qian L, Hong JS. Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases. Glia. 62: 2034-43. PMID 25043383 DOI: 10.1002/Glia.22724 |
0.807 |
|
| 2014 |
Kumar A, Chen SH, Kadiiska MB, Hong JS, Zielonka J, Kalyanaraman B, Mason RP. Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells. Free Radical Biology & Medicine. 73: 51-9. PMID 24746617 DOI: 10.1016/J.Freeradbiomed.2014.04.014 |
0.412 |
|
| 2014 |
Zhang W, Yan ZF, Gao JH, Sun L, Huang XY, Liu Z, Yu SY, Cao CJ, Zuo LJ, Chen ZJ, Hu Y, Wang F, Hong JS, Wang XM. Role and mechanism of microglial activation in iron-induced selective and progressive dopaminergic neurodegeneration. Molecular Neurobiology. 49: 1153-65. PMID 24277523 DOI: 10.1007/S12035-013-8586-4 |
0.445 |
|
| 2013 |
Chen SH, Oyarzabal EA, Hong JS. Preparation of rodent primary cultures for neuron-glia, mixed glia, enriched microglia, and reconstituted cultures with microglia. Methods in Molecular Biology (Clifton, N.J.). 1041: 231-40. PMID 23813383 DOI: 10.1007/978-1-62703-520-0_21 |
0.756 |
|
| 2013 |
Qin L, Liu Y, Hong JS, Crews FT. NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration. Glia. 61: 855-68. PMID 23536230 DOI: 10.1002/glia.22479 |
0.346 |
|
| 2013 |
Mattison HA, Nie H, Gao H, Zhou H, Hong JS, Zhang J. Suppressed pro-inflammatory response of microglia in CX3CR1 knockout mice. Journal of Neuroimmunology. 257: 110-5. PMID 23499256 DOI: 10.1016/j.jneuroim.2013.02.008 |
0.343 |
|
| 2013 |
Zhang W, Zecca L, Wilson B, Ren HW, Wang YJ, Wang XM, Hong JS. Human neuromelanin: an endogenous microglial activator for dopaminergic neuron death. Frontiers in Bioscience (Elite Edition). 5: 1-11. PMID 23276965 DOI: 10.2741/E591 |
0.489 |
|
| 2013 |
Zhou H, Liao J, Aloor J, Nie H, Wilson BC, Fessler MB, Gao HM, Hong JS. CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses. Journal of Immunology (Baltimore, Md. : 1950). 190: 115-25. PMID 23209319 DOI: 10.4049/Jimmunol.1202136 |
0.365 |
|
| 2012 |
Chen SL, Lee SY, Chang YH, Chen SH, Chu CH, Tzeng NS, Lee IH, Chen PS, Yeh TL, Huang SY, Yang YK, Lu RB, Hong JS. Inflammation in patients with schizophrenia: the therapeutic benefits of risperidone plus add-on dextromethorphan. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 656-64. PMID 22730040 DOI: 10.1007/S11481-012-9382-Z |
0.301 |
|
| 2012 |
Wang Q, Shin EJ, Nguyen XK, Li Q, Bach JH, Bing G, Kim WK, Kim HC, Hong JS. Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice. Journal of Neuroinflammation. 9: 124. PMID 22695044 DOI: 10.1186/1742-2094-9-124 |
0.645 |
|
| 2012 |
Gao HM, Zhou H, Hong JS. NADPH oxidases: novel therapeutic targets for neurodegenerative diseases. Trends in Pharmacological Sciences. 33: 295-303. PMID 22503440 DOI: 10.1016/J.Tips.2012.03.008 |
0.431 |
|
| 2012 |
Wang Q, Zhou H, Gao H, Chen SH, Chu CH, Wilson B, Hong JS. Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. Journal of Neuroinflammation. 9: 32. PMID 22340895 DOI: 10.1186/1742-2094-9-32 |
0.571 |
|
| 2012 |
Zhang F, Zhou H, Wilson BC, Shi JS, Hong JS, Gao HM. Fluoxetine protects neurons against microglial activation-mediated neurotoxicity. Parkinsonism & Related Disorders. 18: S213-7. PMID 22166439 DOI: 10.1016/S1353-8020(11)70066-9 |
0.506 |
|
| 2012 |
Zhou H, Zhang F, Chen SH, Zhang D, Wilson B, Hong JS, Gao HM. Rotenone activates phagocyte NADPH oxidase by binding to its membrane subunit gp91phox. Free Radical Biology & Medicine. 52: 303-13. PMID 22094225 DOI: 10.1016/J.Freeradbiomed.2011.10.488 |
0.313 |
|
| 2012 |
Hu X, Zhou H, Zhang D, Yang S, Qian L, Wu HM, Chen PS, Wilson B, Gao HM, Lu RB, Hong JS. Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 187-201. PMID 21870076 DOI: 10.1007/S11481-011-9309-0 |
0.423 |
|
| 2012 |
Chen SH, Wu HM, Ossola B, Schendzielorz N, Wilson BC, Chu CH, Chen SL, Wang Q, Zhang D, Qian L, Li X, Hong JS, Lu RB. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage. British Journal of Pharmacology. 165: 494-505. PMID 21726209 DOI: 10.1111/J.1476-5381.2011.01575.X |
0.656 |
|
| 2012 |
Ossola B, Schendzielorz N, Chen S, Bird GS, Tuominen RK, Männistö PT, Hong J. Corrigendum to “Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia” [Neuropharmacology 61 (2011) 574–582] Neuropharmacology. 62: 1162. DOI: 10.1016/J.Neuropharm.2011.09.020 |
0.363 |
|
| 2012 |
Nam Y, Dang D, Thi Tu T, Bach J, Shin E, Bing G, Hong J, Kim H. Dynorphin Provides Neuroprotection Against Methamphetamine-Induced Neurotoxicity via Activating Glutathione-Dependent Antioxidant Enzymes, but not via Modulating Classical?-Opioid Receptors Free Radical Biology and Medicine. 53: S69. DOI: 10.1016/J.Freeradbiomed.2012.10.208 |
0.315 |
|
| 2011 |
Sheng W, Zong Y, Mohammad A, Ajit D, Cui J, Han D, Hamilton JL, Simonyi A, Sun AY, Gu Z, Hong JS, Weisman GA, Sun GY. Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA₂-IIA expression in astrocytes and microglia. Journal of Neuroinflammation. 8: 121. PMID 21943492 DOI: 10.1186/1742-2094-8-121 |
0.403 |
|
| 2011 |
Flood PM, Qian L, Peterson LJ, Zhang F, Shi JS, Gao HM, Hong JS. Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease. Parkinson's Disease. 2011: 216298. PMID 21603248 DOI: 10.4061/2011/216298 |
0.419 |
|
| 2011 |
Ossola B, Schendzielorz N, Chen SH, Bird GS, Tuominen RK, Männistö PT, Hong JS. Amantadine protects dopamine neurons by a dual action: reducing activation of microglia and inducing expression of GDNF in astroglia [corrected]. Neuropharmacology. 61: 574-82. PMID 21586298 DOI: 10.1016/J.Neuropharm.2011.04.030 |
0.51 |
|
| 2011 |
Gao HM, Hong JS. Gene-environment interactions: key to unraveling the mystery of Parkinson's disease. Progress in Neurobiology. 94: 1-19. PMID 21439347 DOI: 10.1016/J.Pneurobio.2011.03.005 |
0.34 |
|
| 2011 |
Qian L, Wu HM, Chen SH, Zhang D, Ali SF, Peterson L, Wilson B, Lu RB, Hong JS, Flood PM. β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway. Journal of Immunology (Baltimore, Md. : 1950). 186: 4443-54. PMID 21335487 DOI: 10.4049/Jimmunol.1002449 |
0.382 |
|
| 2011 |
Gao HM, Zhou H, Zhang F, Wilson BC, Kam W, Hong JS. HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1081-92. PMID 21248133 DOI: 10.1523/Jneurosci.3732-10.2011 |
0.539 |
|
| 2011 |
Gao HM, Zhang F, Zhou H, Kam W, Wilson B, Hong JS. Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. Environmental Health Perspectives. 119: 807-14. PMID 21245015 DOI: 10.1289/Ehp.1003013 |
0.439 |
|
| 2011 |
Zhang D, Hu X, Qian L, Chen SH, Zhou H, Wilson B, Miller DS, Hong JS. Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity. Journal of Neuroinflammation. 8: 3. PMID 21232086 DOI: 10.1186/1742-2094-8-3 |
0.462 |
|
| 2011 |
Liu Y, Lo YC, Qian L, Crews FT, Wilson B, Chen HL, Wu HM, Chen SH, Wei K, Lu RB, Ali S, Hong JS. Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation. Neuropharmacology. 60: 373-80. PMID 20950631 DOI: 10.1016/J.Neuropharm.2010.10.002 |
0.342 |
|
| 2011 |
Zhang W, Phillips K, Wielgus AR, Liu J, Albertini A, Zucca FA, Faust R, Qian SY, Miller DS, Chignell CF, Wilson B, Jackson-Lewis V, Przedborski S, Joset D, Loike J, ... Hong JS, et al. Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease. Neurotoxicity Research. 19: 63-72. PMID 19957214 DOI: 10.1007/S12640-009-9140-Z |
0.496 |
|
| 2010 |
Shin EJ, Hong JS, Kim HC. Neuropsychopharmacological understanding for therapeutic application of morphinans. Archives of Pharmacal Research. 33: 1575-87. PMID 21052935 DOI: 10.1007/S12272-010-1009-4 |
0.383 |
|
| 2010 |
Luo L, Rodriguez E, Jerbi K, Lachaux JP, Martinerie J, Corbetta M, Shulman GL, Piomelli D, Turrigiano GG, Nelson SB, Joëls M, de Kloet ER, Holsboer F, Amodio DM, Frith CD, ... ... Hong JS, et al. Ten years of Nature Reviews Neuroscience: insights from the highly cited. Nature Reviews. Neuroscience. 11: 718-26. PMID 20852655 DOI: 10.1038/Nrn2912 |
0.536 |
|
| 2010 |
Qian L, Flood PM, Hong JS. Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 971-9. PMID 20571837 DOI: 10.1007/S00702-010-0428-1 |
0.432 |
|
| 2010 |
Zhang F, Shi JS, Zhou H, Wilson B, Hong JS, Gao HM. Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions. Molecular Pharmacology. 78: 466-77. PMID 20554604 DOI: 10.1124/Mol.110.064535 |
0.551 |
|
| 2010 |
Polikov VS, Hong JS, Reichert WM. Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires. Journal of Neuroscience Methods. 190: 180-7. PMID 20470825 DOI: 10.1016/J.Jneumeth.2010.05.002 |
0.346 |
|
| 2010 |
Zhang F, Qian L, Flood PM, Shi JS, Hong JS, Gao HM. Inhibition of IkappaB kinase-beta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 333: 822-33. PMID 20190013 DOI: 10.1124/Jpet.110.165829 |
0.456 |
|
| 2010 |
Zhang D, Hu X, Qian L, O'Callaghan JP, Hong JS. Astrogliosis in CNS pathologies: is there a role for microglia? Molecular Neurobiology. 41: 232-41. PMID 20148316 DOI: 10.1007/S12035-010-8098-4 |
0.478 |
|
| 2010 |
Levesque S, Wilson B, Gregoria V, Thorpe LB, Dallas S, Polikov VS, Hong JS, Block ML. Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity. Brain : a Journal of Neurology. 133: 808-21. PMID 20123724 DOI: 10.1093/Brain/Awp333 |
0.687 |
|
| 2010 |
Zhang F, Shi JS, Zhou H, Wilson B, Hong JS, Gao HM. Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions (Molecular Pharmacology (2010) 78, (466-477)) Molecular Pharmacology. 78: 981. DOI: 10.1124/mol.78.5.981 |
0.329 |
|
| 2009 |
Wu HM, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB. Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2344-57. PMID 19536110 DOI: 10.1038/Npp.2009.64 |
0.432 |
|
| 2009 |
Zhang D, Hu X, Qian L, Wilson B, Lee C, Flood P, Langenbach R, Hong JS. Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro. Toxicology and Applied Pharmacology. 238: 64-70. PMID 19397918 DOI: 10.1016/J.Taap.2009.04.015 |
0.43 |
|
| 2009 |
Qian L, Hu X, Zhang D, Snyder A, Wu HM, Li Y, Wilson B, Lu RB, Hong JS, Flood PM. beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway. Glia. 57: 1600-9. PMID 19330844 DOI: 10.1002/Glia.20873 |
0.325 |
|
| 2008 |
Hu X, Zhang D, Pang H, Caudle WM, Li Y, Gao H, Liu Y, Qian L, Wilson B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS. Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7194-204. PMID 18981141 DOI: 10.4049/Jimmunol.181.10.7194 |
0.713 |
|
| 2008 |
Wu X, Chen PS, Dallas S, Wilson B, Block ML, Wang CC, Kinyamu H, Lu N, Gao X, Leng Y, Chuang DM, Zhang W, Lu RB, Hong JS. Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 1123-34. PMID 18611290 DOI: 10.1017/S1461145708009024 |
0.676 |
|
| 2008 |
Qian L, Wei SJ, Zhang D, Hu X, Xu Z, Wilson B, El-Benna J, Hong JS, Flood PM. Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia. Journal of Immunology (Baltimore, Md. : 1950). 181: 660-8. PMID 18566433 DOI: 10.4049/Jimmunol.181.1.660 |
0.377 |
|
| 2008 |
Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS. Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity. Journal of Neuroinflammation. 5: 21. PMID 18507839 DOI: 10.1186/1742-2094-5-21 |
0.557 |
|
| 2008 |
Hartz AM, Bauer B, Block ML, Hong JS, Miller DS. Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2723-33. PMID 18474546 DOI: 10.1096/Fj.08-106997 |
0.621 |
|
| 2008 |
Liu Y, Qin L, Wilson B, Wu X, Qian L, Granholm AC, Crews FT, Hong JS. Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits. Neurotoxicology. 29: 864-70. PMID 18471886 DOI: 10.1016/j.neuro.2008.02.014 |
0.324 |
|
| 2008 |
Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS. Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration? Environmental Health Perspectives. 116: 593-8. PMID 18470306 DOI: 10.1289/Ehp.11031 |
0.694 |
|
| 2008 |
Yang S, Zhang D, Yang Z, Hu X, Qian S, Liu J, Wilson B, Block M, Hong JS. Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture. Neurochemical Research. 33: 2044-53. PMID 18368483 DOI: 10.1007/S11064-008-9675-Z |
0.712 |
|
| 2008 |
Liu B, Wang K, Gao H, Mandavilli B, Wang J, Hong J. Molecular consequences of activated microglia in the brain: overactivation induces apoptosis Journal of Neurochemistry. 77: 182-189. DOI: 10.1046/J.1471-4159.2001.00216.X |
0.325 |
|
| 2007 |
Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM. NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. Parkinsonism & Related Disorders. 13: S316-20. PMID 18267257 DOI: 10.1016/S1353-8020(08)70023-3 |
0.661 |
|
| 2007 |
Block ML, Hong JS. Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochemical Society Transactions. 35: 1127-32. PMID 17956294 DOI: 10.1042/Bst0351127 |
0.698 |
|
| 2007 |
Qian L, Xu Z, Zhang W, Wilson B, Hong JS, Flood PM. Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase. Journal of Neuroinflammation. 4: 23. PMID 17880684 DOI: 10.1186/1742-2094-4-23 |
0.55 |
|
| 2007 |
Chen PS, Wang CC, Bortner CD, Peng GS, Wu X, Pang H, Lu RB, Gean PW, Chuang DM, Hong JS. Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity. Neuroscience. 149: 203-12. PMID 17850978 DOI: 10.1016/J.Neuroscience.2007.06.053 |
0.461 |
|
| 2007 |
Pei Z, Pang H, Qian L, Yang S, Wang T, Zhang W, Wu X, Dallas S, Wilson B, Reece JM, Miller DS, Hong JS, Block ML. MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity. Glia. 55: 1362-73. PMID 17654704 DOI: 10.1002/Glia.20545 |
0.688 |
|
| 2007 |
Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM. Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity. Journal of Immunology (Baltimore, Md. : 1950). 179: 1198-209. PMID 17617613 DOI: 10.4049/Jimmunol.179.2.1198 |
0.428 |
|
| 2007 |
Zhang W, Dallas S, Zhang D, Guo JP, Pang H, Wilson B, Miller DS, Chen B, Zhang W, McGeer PL, Hong JS, Zhang J. Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein. Glia. 55: 1178-88. PMID 17600340 DOI: 10.1002/Glia.20532 |
0.31 |
|
| 2007 |
Yang Z, Yang S, Qian SY, Hong JS, Kadiiska MB, Tennant RW, Waalkes MP, Liu J. Cadmium-induced toxicity in rat primary mid-brain neuroglia cultures: role of oxidative stress from microglia. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 488-94. PMID 17483498 DOI: 10.1093/Toxsci/Kfm106 |
0.391 |
|
| 2007 |
Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. The Journal of Pharmacology and Experimental Therapeutics. 321: 892-901. PMID 17371805 DOI: 10.1124/Jpet.107.120188 |
0.358 |
|
| 2007 |
Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia. 55: 453-62. PMID 17203472 DOI: 10.1002/Glia.20467 |
0.673 |
|
| 2007 |
Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews. Neuroscience. 8: 57-69. PMID 17180163 DOI: 10.1038/Nrn2038 |
0.659 |
|
| 2007 |
Kim YS, Choi DH, Block ML, Lorenzl S, Yang L, Kim YJ, Sugama S, Cho BP, Hwang O, Browne SE, Kim SY, Hong JS, Beal MF, Joh TH. A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 179-87. PMID 17116747 DOI: 10.1096/Fj.06-5865Com |
0.702 |
|
| 2006 |
Zhang W, Shin EJ, Wang T, Lee PH, Pang H, Wie MB, Kim WK, Kim SJ, Huang WH, Wang Y, Zhang W, Hong JS, Kim HC. 3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2496-511. PMID 17142799 DOI: 10.1096/Fj.06-6006Com |
0.474 |
|
| 2006 |
Yang S, Yang J, Yang Z, Chen P, Fraser A, Zhang W, Pang H, Gao X, Wilson B, Hong JS, Block ML. Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. 319: 595-603. PMID 16891616 DOI: 10.1124/Jpet.106.102236 |
0.714 |
|
| 2006 |
Polikov VS, Block ML, Fellous JM, Hong JS, Reichert WM. In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS. Biomaterials. 27: 5368-76. PMID 16842846 DOI: 10.1016/J.Biomaterials.2006.06.018 |
0.626 |
|
| 2006 |
Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. The Journal of Pharmacology and Experimental Therapeutics. 319: 44-52. PMID 16807359 DOI: 10.1124/Jpet.106.106351 |
0.657 |
|
| 2006 |
Wang T, Zhang W, Pei Z, Block M, Wilson B, Reece JM, Miller DS, Hong JS. Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 906-15. PMID 16675848 DOI: 10.1096/Fj.05-5053Com |
0.705 |
|
| 2006 |
Block ML, Li G, Qin L, Wu X, Pei Z, Wang T, Wilson B, Yang J, Hong JS. Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 251-8. PMID 16449797 DOI: 10.1096/Fj.05-4553Com |
0.674 |
|
| 2006 |
McLaughlin P, Zhou Y, Ma T, Liu J, Zhang W, Hong JS, Kovacs M, Zhang J. Proteomic analysis of microglial contribution to mouse strain-dependent dopaminergic neurotoxicity. Glia. 53: 567-82. PMID 16419087 DOI: 10.1002/Glia.20294 |
0.452 |
|
| 2005 |
Hong JS. Role of inflammation in the pathogenesis of Parkinson's disease: models, mechanisms, and therapeutic interventions. Annals of the New York Academy of Sciences. 1053: 151-2. PMID 16179518 DOI: 10.1016/J.Ejps.2008.02.012 |
0.318 |
|
| 2005 |
Qin L, Liu Y, Qian X, Hong JS, Block ML. Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection. Annals of the New York Academy of Sciences. 1053: 107-20. PMID 16179514 DOI: 10.1111/J.1749-6632.2005.Tb00016.X |
0.687 |
|
| 2005 |
He YY, Huang JL, Block ML, Hong JS, Chignell CF. Role of phagocyte oxidase in UVA-induced oxidative stress and apoptosis in keratinocytes. The Journal of Investigative Dermatology. 125: 560-6. PMID 16117799 DOI: 10.1111/J.0022-202X.2005.23851.X |
0.602 |
|
| 2005 |
Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Progress in Neurobiology. 76: 77-98. PMID 16081203 DOI: 10.1016/J.Pneurobio.2005.06.004 |
0.676 |
|
| 2005 |
Yin S, Guan Z, Tang Y, Zhao J, Hong J, Zhang W. Abnormal expression of epilepsy-related gene ERG1/NSF in the spontaneous recurrent seizure rats with spatial learning memory deficits induced by kainic acid Brain Research. 1053: 195-202. PMID 16039622 DOI: 10.1016/J.Brainres.2005.06.054 |
0.3 |
|
| 2005 |
Qin L, Li G, Qian X, Liu Y, Wu X, Liu B, Hong JS, Block ML. Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation. Glia. 52: 78-84. PMID 15920727 DOI: 10.1002/Glia.20225 |
0.649 |
|
| 2005 |
Wu XF, Block ML, Zhang W, Qin L, Wilson B, Zhang WQ, Veronesi B, Hong JS. The role of microglia in paraquat-induced dopaminergic neurotoxicity. Antioxidants & Redox Signaling. 7: 654-61. PMID 15890010 DOI: 10.1089/Ars.2005.7.654 |
0.694 |
|
| 2005 |
Wang T, Pei Z, Zhang W, Liu B, Langenbach R, Lee C, Wilson B, Reece JM, Miller DS, Hong JS. MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1134-6. PMID 15845609 DOI: 10.1096/Fj.04-2457Fje |
0.517 |
|
| 2005 |
Qin L, Block ML, Liu Y, Bienstock RJ, Pei Z, Zhang W, Wu X, Wilson B, Burka T, Hong JS. Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 550-7. PMID 15791005 DOI: 10.1096/Fj.04-2857Com |
0.632 |
|
| 2005 |
Zhang W, Wang T, Pei Z, Miller DS, Wu X, Block ML, Wilson B, Zhang W, Zhou Y, Hong JS, Zhang J. Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 533-42. PMID 15791003 DOI: 10.1096/Fj.04-2751Com |
0.646 |
|
| 2005 |
Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS. Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 489-96. PMID 15790998 DOI: 10.1096/fj.04-2555com |
0.725 |
|
| 2005 |
Peng GS, Li G, Tzeng NS, Chen PS, Chuang DM, Hsu YD, Yang S, Hong JS. Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia. Brain Research. Molecular Brain Research. 134: 162-9. PMID 15790540 DOI: 10.1016/j.molbrainres.2004.10.021 |
0.445 |
|
| 2005 |
Li G, Liu Y, Tzeng NS, Cui G, Block ML, Wilson B, Qin L, Wang T, Liu B, Liu J, Hong JS. Protective effect of dextromethorphan against endotoxic shock in mice. Biochemical Pharmacology. 69: 233-40. PMID 15627475 DOI: 10.1016/J.Bcp.2004.10.003 |
0.655 |
|
| 2005 |
Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS. 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 395-7. PMID 15596482 DOI: 10.1096/Fj.04-1586Fje |
0.542 |
|
| 2005 |
Hong J. Role of Inflammation in the Pathogenesis of Parkinson's Disease Annals of the New York Academy of Sciences. 1053: 151-152. DOI: 10.1111/J.1749-6632.2005.Tb00020.X |
0.341 |
|
| 2004 |
Zhang W, Hong JS, Kim HC, Zhang W, Block ML. Morphinan neuroprotection: new insight into the therapy of neurodegeneration. Critical Reviews in Neurobiology. 16: 271-302. PMID 15862109 DOI: 10.1615/Critrevneurobiol.V16.I4.30 |
0.631 |
|
| 2004 |
Block ML, Wu X, Pei Z, Li G, Wang T, Qin L, Wilson B, Yang J, Hong JS, Veronesi B. Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1618-20. PMID 15319363 DOI: 10.1096/Fj.04-1945Fje |
0.692 |
|
| 2004 |
Wang V, Chia LG, Ni DR, Cheng LJ, Ho YP, Cheng FC, Hong JS. Effects of the combined treatment of naloxone and indomethacin on catecholamines and behavior after intranigral lipopolysaccharide injection. Neurochemical Research. 29: 341-6. PMID 15002729 DOI: 10.1023/B:Nere.0000013736.80749.4B |
0.359 |
|
| 2004 |
Wang T, Qin L, Liu B, Liu Y, Wilson B, Eling TE, Langenbach R, Taniura S, Hong JS. Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia. Journal of Neurochemistry. 88: 939-47. PMID 14756815 DOI: 10.1046/J.1471-4159.2003.02242.X |
0.417 |
|
| 2004 |
Zhang W, Wang T, Qin L, Gao HM, Wilson B, Ali SF, Zhang W, Hong JS, Liu B. Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 589-91. PMID 14734632 DOI: 10.1096/Fj.03-0983Fje |
0.478 |
|
| 2004 |
Wang T, Liu B, Zhang W, Wilson B, Hong JS. Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation. The Journal of Pharmacology and Experimental Therapeutics. 308: 975-83. PMID 14718612 DOI: 10.1124/Jpet.103.059683 |
0.546 |
|
| 2004 |
Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. The Journal of Biological Chemistry. 279: 1415-21. PMID 14578353 DOI: 10.1074/Jbc.M307657200 |
0.713 |
|
| 2003 |
Gao HM, Liu B, Zhang W, Hong JS. Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1957-9. PMID 12923073 DOI: 10.1096/Fj.03-0203Fje |
0.481 |
|
| 2003 |
Gao HM, Liu B, Zhang W, Hong JS. Novel anti-inflammatory therapy for Parkinson's disease. Trends in Pharmacological Sciences. 24: 395-401. PMID 12915048 DOI: 10.1016/S0165-6147(03)00176-7 |
0.324 |
|
| 2003 |
Gao HM, Liu B, Zhang W, Hong JS. Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1954-6. PMID 12897068 DOI: 10.1096/Fj.03-0109Fje |
0.511 |
|
| 2003 |
Gao HM, Liu B, Hong JS. Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6181-7. PMID 12867501 DOI: 10.1523/Jneurosci.23-15-06181.2003 |
0.513 |
|
| 2003 |
Liu B, Gao HM, Hong JS. Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation. Environmental Health Perspectives. 111: 1065-73. PMID 12826478 DOI: 10.1289/Ehp.6361 |
0.397 |
|
| 2003 |
Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS. Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. The Journal of Pharmacology and Experimental Therapeutics. 305: 212-8. PMID 12649371 DOI: 10.1124/Jpet.102.043166 |
0.552 |
|
| 2003 |
Gao HM, Hong JS, Zhang W, Liu B. Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1228-36. PMID 12598611 DOI: 10.1523/Jneurosci.23-04-01228.2003 |
0.49 |
|
| 2003 |
Liu B, Hong JS. Primary rat mesencephalic neuron-glia, neuron-enriched, microglia-enriched, and astroglia-enriched cultures Methods in Molecular Medicine. 79: 387-395. PMID 12506711 DOI: 10.1385/1-59259-358-5:387 |
0.406 |
|
| 2003 |
Liu B, Hong JS. Neuroprotective effect of naloxone in inflammation-mediated dopaminergic neurodegeneration. Dissociation from the involvement of opioid receptors Methods in Molecular Medicine. 79: 43-54. PMID 12506689 DOI: 10.1385/1-59259-358-5:43 |
0.311 |
|
| 2003 |
Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention Journal of Pharmacology and Experimental Therapeutics. 304: 1-7. PMID 12490568 DOI: 10.1124/Jpet.102.035048 |
0.41 |
|
| 2002 |
Wang MJ, Lin WW, Chen HL, Chang YH, Ou HC, Kuo JS, Hong JS, Jeng KC. Silymarin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity by inhibiting microglia activation. The European Journal of Neuroscience. 16: 2103-12. PMID 12473078 DOI: 10.1046/J.1460-9568.2002.02290.X |
0.476 |
|
| 2002 |
Qin L, Liu Y, Cooper C, Liu B, Wilson B, Hong JS. Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. Journal of Neurochemistry. 83: 973-83. PMID 12421370 DOI: 10.1046/J.1471-4159.2002.01210.X |
0.432 |
|
| 2002 |
Liu Y, Qin L, Wilson BC, An L, Hong JS, Liu B. Inhibition by naloxone stereoisomers of beta-amyloid peptide (1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons. The Journal of Pharmacology and Experimental Therapeutics. 302: 1212-9. PMID 12183682 DOI: 10.1124/Jpet.102.035956 |
0.432 |
|
| 2002 |
Jeohn GH, Cooper CL, Jang KJ, Kim HC, Hong JS. Gö6976 protects mesencephalic neurons from lipopolysaccharide-elicited death by inhibiting p38 MAP kinase phosphorylation. Annals of the New York Academy of Sciences. 962: 347-59. PMID 12076986 DOI: 10.1111/J.1749-6632.2002.Tb04079.X |
0.466 |
|
| 2002 |
Jeohn GH, Cooper CL, Wilson B, Chang RC, Jang KJ, Kim HC, Liu B, Hong JS. p38 MAP kinase is involved in lipopolysaccharide-induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures. Annals of the New York Academy of Sciences. 962: 332-46. PMID 12076985 DOI: 10.1111/J.1749-6632.2002.Tb04078.X |
0.518 |
|
| 2002 |
Liu B, Gao HM, Wang JY, Jeohn GH, Cooper CL, Hong JS. Role of nitric oxide in inflammation-mediated neurodegeneration. Annals of the New York Academy of Sciences. 962: 318-31. PMID 12076984 DOI: 10.1111/J.1749-6632.2002.Tb04077.X |
0.445 |
|
| 2002 |
Cooper CL, Jeohn GH, Tobias P, Hong JS. Serum-dependence of LPS-induced neurotoxicity in rat cortical neurons. Annals of the New York Academy of Sciences. 962: 306-17. PMID 12076983 DOI: 10.1111/J.1749-6632.2002.Tb04076.X |
0.415 |
|
| 2002 |
Gao HM, Jiang J, Wilson B, Zhang W, Hong JS, Liu B. Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. Journal of Neurochemistry. 81: 1285-97. PMID 12068076 DOI: 10.1046/J.1471-4159.2002.00928.X |
0.524 |
|
| 2002 |
Ling Z, Gayle DA, Ma SY, Lipton JW, Tong CW, Hong JS, Carvey PM. In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain. Movement Disorders : Official Journal of the Movement Disorder Society. 17: 116-24. PMID 11835448 DOI: 10.1002/Mds.10078 |
0.328 |
|
| 2002 |
Gao HM, Hong JS, Zhang W, Liu B. Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 782-90. PMID 11826108 DOI: 10.1523/Jneurosci.22-03-00782.2002 |
0.509 |
|
| 2001 |
Chen C, Liao S, Chen W, Hong J, Kuo J. Cerebral ischemia/reperfusion injury in rat brain: effects of naloxone. Neuroreport. 12: 1245-1249. PMID 11338200 DOI: 10.1097/00001756-200105080-00038 |
0.311 |
|
| 2001 |
Chang RC, Chen W, Hudson P, Wilson B, Han DS, Hong JS. Neurons reduce glial responses to lipopolysaccharide (LPS) and prevent injury of microglial cells from over-activation by LPS. Journal of Neurochemistry. 76: 1042-9. PMID 11181823 DOI: 10.1046/J.1471-4159.2001.00111.X |
0.475 |
|
| 2001 |
Chang RC, Hudson P, Wilson B, Liu B, Abel H, Hemperly J, Hong JS. Immune modulatory effects of neural cell adhesion molecules on lipopolysaccharide-induced nitric oxide production by cultured glia. Brain Research. Molecular Brain Research. 81: 197-201. PMID 11000493 DOI: 10.1016/S0169-328X(00)00175-3 |
0.426 |
|
| 2000 |
Feng Z, Hong JS, Qi Q, Han Y, Wilson B, Iadarola M, Tiao N, Bing G. Cloning and expression of MP13 gene from rat hippocampus, a new factor related to guanosine triphosphate regulation Neuroscience Letters. 296: 129-132. PMID 11108998 DOI: 10.1016/S0304-3940(00)01641-4 |
0.534 |
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| 2000 |
Kong L, Jeohn G, Hudson PM, Du L, Liu B, Hong J. Reduction of Lipopolysaccharide-Induced Neurotoxicity in Mouse Mixed Cortical Neuron/Glia Cultures by Ultralow Concentrations of Dynorphins Journal of Biomedical Science. 7: 241-247. PMID 10810243 DOI: 10.1007/Bf02255472 |
0.432 |
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| 2000 |
Chang RC, Rota C, Glover RE, Mason RP, Hong JS. A novel effect of an opioid receptor antagonist, naloxone, on the production of reactive oxygen species by microglia: a study by electron paramagnetic resonance spectroscopy. Brain Research. 854: 224-9. PMID 10784126 DOI: 10.1016/S0006-8993(99)02267-2 |
0.353 |
|
| 2000 |
Chang RC, Hudson P, Wilson B, Haddon L, Hong JS. Influence of neurons on lipopolysaccharide-stimulated production of nitric oxide and tumor necrosis factor-alpha by cultured glia. Brain Research. 853: 236-44. PMID 10640621 DOI: 10.1016/S0006-8993(99)02255-6 |
0.463 |
|
| 2000 |
Kim H, Bing G, Jhoo W, Ko KH, Kim WK, Suh JH, Kim SJ, Kato K, Hong JS. Changes of hippocampal Cu/Zn-superoxide dismutase after kainate treatment in the rat. Brain Research. 853: 215-26. PMID 10640619 DOI: 10.1016/S0006-8993(99)02254-4 |
0.374 |
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| 2000 |
Kim W, Mohney RP, Wilson B, Jeohn G, Liu B, Hong J. Regional Difference in Susceptibility to Lipopolysaccharide-Induced Neurotoxicity in the Rat Brain: Role of Microglia The Journal of Neuroscience. 20: 6309-6316. DOI: 10.1523/Jneurosci.20-16-06309.2000 |
0.473 |
|
| 1999 |
Serova LI, Nankova BB, Feng Z, Hong JS, Hutt M, Sabban EL. Heightened transcription for enzymes involved in norepinephrine biosynthesis in the rat locus coeruleus by immobilization stress Biological Psychiatry. 45: 853-862. PMID 10202573 DOI: 10.1016/S0006-3223(98)90360-2 |
0.303 |
|
| 1998 |
Jeohn G, Kong L, Wilson B, Hudson P, Hong J. Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures. Journal of Neuroimmunology. 85: 1-10. PMID 9626992 DOI: 10.1016/S0165-5728(97)00204-X |
0.455 |
|
| 1997 |
Feng Z, Zhang W, Hudson P, Bing G, Feng W, Hong JS. Characterization of the long-lasting activator protein-1 complex induced by kainic acid treatment Brain Research. 770: 53-59. PMID 9372202 DOI: 10.1016/S0006-8993(97)00744-0 |
0.301 |
|
| 1997 |
Bing G, Wilson B, Hudson P, Jin L, Feng Z, Zhang W, Bing R, Hong JS. A single dose of kainic acid elevates the levels of enkephalins and activator protein-1 transcription factors in the hippocampus for up to 1 year Proceedings of the National Academy of Sciences of the United States of America. 94: 9422-9427. PMID 9256498 DOI: 10.1073/Pnas.94.17.9422 |
0.315 |
|
| 1997 |
Kong LY, Lai C, Wilson BC, Simpson JN, Hong JS. Protein tyrosine kinase inhibitors decrease lipopolysaccharide-induced proinflammatory cytokine production in mixed glia, microglia-enriched or astrocyte-enriched cultures. Neurochemistry International. 30: 491-7. PMID 9106265 DOI: 10.1016/S0197-0186(96)00086-1 |
0.338 |
|
| 1996 |
Bronstein DM, Pennypacker KR, Lee H, Hong JS. Methamphetamine-induced changes in AP-1 binding and dynorphin in the striatum: Correlated, not causally related events? Biological Signals. 5: 317-333. PMID 9116798 DOI: 10.1159/000109205 |
0.315 |
|
| 1996 |
Kong L, McMillian MK, Maronpot R, Hong J. Protein tyrosine kinase inhibitors suppress the production of nitric oxide in mixed glia, microglia-enriched or astrocyte-enriched cultures Brain Research. 729: 102-109. DOI: 10.1016/0006-8993(96)00417-9 |
0.402 |
|
| 1995 |
Suh HW, Hudson PM, Hong JS. Expression of the proenkephalin A gene and [Met5]-enkephalin secretion induced by arachidonic acid in bovine adrenal medullary chromaffin cells: involvement of second messengers. Journal of Neurochemistry. 64: 608-13. PMID 7830054 DOI: 10.1046/J.1471-4159.1995.64020608.X |
0.326 |
|
| 1995 |
Das KP, McMillian MK, Bing G, Hong JS. Modulatory effects of [Met5]-enkephalin on interleukin-1 beta secretion from microglia in mixed brain cell cultures. Journal of Neuroimmunology. 62: 9-17. PMID 7499497 DOI: 10.1016/0165-5728(95)00083-E |
0.338 |
|
| 1995 |
McMillian M, Kong LY, Sawin SM, Wilson B, Das K, Hudson P, Hong JS, Bing G. Selective killing of cholinergic neurons by microglial activation in basal forebrain mixed neuronal/glial cultures Biochemical and Biophysical Research Communications. 215: 572-577. PMID 7487994 DOI: 10.1006/Bbrc.1995.2503 |
0.472 |
|
| 1994 |
Stachowiak MK, Goc A, Hong JS, Poisner A, Jiang HK, Stachowiak EK. Regulation of tyrosine hydroxylase gene expression in depolarized non-transformed bovine adrenal medullary cells: second messenger systems and promoter mechanisms Molecular Brain Research. 22: 309-319. PMID 7912405 DOI: 10.1016/0169-328X(94)90059-0 |
0.305 |
|
| 1994 |
Suh HW, McMillian MK, Hudson PM, Hong JS. Effects of staurosporine on cell morphology, expression of the proenkephalin gene and the secretion of [Met5]-enkephalin in bovine adrenal medullary chromaffin cells. Biological Signals. 3: 247-58. PMID 7704105 DOI: 10.1159/000109552 |
0.312 |
|
| 1994 |
Pennypacker K, Thai L, Hong J, McMillian M. Prolonged expression of AP-1 transcription factors in the rat hippocampus after systemic kainate treatment The Journal of Neuroscience. 14: 3998-4006. DOI: 10.1523/Jneurosci.14-07-03998.1994 |
0.311 |
|
| 1993 |
Suh HH, McMillian MK, Hudson PM, Pennypacker KR, Hong JS. Expression of the Proenkephalin A Gene and [Met(5)]enkephalin Secretion Induced by Prostaglandin E(2) in Bovine Adrenal Medullary Chromaffin Cells: Involvement of Second Messengers. Molecular and Cellular Neurosciences. 4: 113-20. PMID 19912914 DOI: 10.1006/Mcne.1993.1013 |
0.33 |
|
| 1993 |
Suh HH, Hudson P, McMillian MK, Hong JS. Pertussis toxin stimulates the secretion of [Met5]-enkephalin and the expression of proenkephalin A mRNA in bovine adrenal medullary chromaffin cells. Biological Signals. 1: 257-65. PMID 1284924 DOI: 10.1159/000109331 |
0.304 |
|
| 1992 |
Mar E, Suh HH, Hong J. Regulation of proenkephalin expression in C6 rat glioma cells Molecular and Cellular Neuroscience. 3: 518-528. PMID 19912895 DOI: 10.1016/1044-7431(92)90064-9 |
0.321 |
|
| 1992 |
Mar EC, Iadarola MJ, Hong JS. Regulation of the expression of proenkephalin mRNA in bovine adrenal chromaffin cells: Role of proto-oncogenes. Molecular and Cellular Neurosciences. 3: 508-17. PMID 19912894 DOI: 10.1016/1044-7431(92)90063-8 |
0.496 |
|
| 1992 |
He XP, Lee PHK, Pennypacker KR, Tuominen RK, Mar EC, Thai L, Hong JS. Characterization of dynorphin-containing neurons on dissociated dentate gyrus cell cultures Brain Research. 594: 91-98. PMID 1361409 DOI: 10.1016/0006-8993(92)91032-A |
0.388 |
|
| 1991 |
Tuominen RK, Hudson PM, McMillian MK, Ye H, Stachowiak MK, Hong JS. Long-term activation of protein kinase C by angiotensin II in cultured bovine adrenal medullary cells Journal of Neurochemistry. 56: 1292-1298. PMID 2002341 DOI: 10.1111/J.1471-4159.1991.Tb11424.X |
0.334 |
|
| 1986 |
Herr DW, Hong JS, Chen P, Tilson HA, Harry GJ. Pharmacological modification of DDT-induced tremor and hyperthermia in rats: distributional factors. Psychopharmacology. 89: 278-83. PMID 3088650 DOI: 10.1007/Bf00174359 |
0.303 |
|
| 1983 |
Hong JS, Tilson HA, Hudson P, Ali SF, Wilson WE, Hunter V. Correlation of neurochemical and behavioral effects of triethyl lead chloride in rats. Toxicology and Applied Pharmacology. 69: 471-9. PMID 6192548 DOI: 10.1016/0041-008X(83)90270-3 |
0.314 |
|
| 1978 |
Gale K, Costa E, Toffano G, Hong JS, Guidotti A. Evidence for a role of nigral gamma-aminobutyric acid and substance P in the haloperidol-induced activation of striatal tyrosine hydroxylase. The Journal of Pharmacology and Experimental Therapeutics. 206: 29-37. PMID 26799 |
0.477 |
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