Philip E. Dawson, Ph.D. - Publications

Affiliations: 
1997- Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Website:
http://www.scripps.edu/dawson/

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Adams ZC, Silvestri AP, Chiorean S, Flood DT, Balo BP, Shi Y, Holcomb M, Walsh SI, Maillie CA, Pierens GK, Forli S, Rosengren KJ, Dawson PE. Stretching Peptides to Generate Small Molecule β-Strand Mimics. Acs Central Science. 9: 648-656. PMID 37122474 DOI: 10.1021/acscentsci.2c01462  0.375
2022 Bird MJ, Dawson PE. A Shelf Stable Fmoc Hydrazine Resin for the Synthesis of Peptide Hydrazides. Peptide Science (Hoboken, N.J.). 114. PMID 36387422 DOI: 10.1002/pep2.24268  0.344
2022 Adams ZC, Olson EJ, Lopez-Silva TL, Lian Z, Kim AY, Holcomb M, Zimmermann J, Adhikary R, Dawson PE. Direct observation of peptide hydrogel self-assembly. Chemical Science. 13: 10020-10028. PMID 36128231 DOI: 10.1039/d1sc06562a  0.302
2020 Denisov SS, Ramírez-Escudero M, Heinzmann ACA, Ippel JH, Dawson PE, Koenen RR, Hackeng TM, Janssen BJC, Dijkgraaf I. Structural characterization of anti-CCL5 activity of the tick salivary protein Evasin-4. The Journal of Biological Chemistry. PMID 32817341 DOI: 10.1074/Jbc.Ra120.013891  0.36
2020 Hackenberger CPR, Dawson PE, Chen YX, Hojo H. Modern Peptide and Protein Chemistry: Reaching New Heights. The Journal of Organic Chemistry. 85: 1328-1330. PMID 32028772 DOI: 10.1021/Acs.Joc.0C00104  0.461
2020 Adhikary R, Dawson PE. In Situ Neutralization Protocols for Boc-SPPS. Methods in Molecular Biology (Clifton, N.J.). 2103: 29-40. PMID 31879917 DOI: 10.1007/978-1-0716-0227-0_3  0.408
2019 Won Y, Jeon H, Pagar AD, Patil MD, Nadarajan SP, Flood DT, Dawson PE, Yun H. In vivo biosynthesis of tyrosine analogs and their concurrent incorporation into a residue-specific manner for enzyme engineering. Chemical Communications (Cambridge, England). PMID 31789331 DOI: 10.1039/C9Cc08503C  0.378
2019 Flood DT, Asai S, Zhang X, Wang J, Yoon L, Adams ZC, Dillingham BC, Sanchez BB, Vantourout JC, Flanagan ME, Piotrowski DW, Richardson PF, Green SA, Shenvi RA, Chen JS, ... ... Dawson PE, et al. Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support. Journal of the American Chemical Society. PMID 31136164 DOI: 10.1021/Jacs.9B03774  0.324
2019 Weidmann J, Schnölzer M, Dawson PE, Hoheisel JD. Copying Life: Synthesis of an Enzymatically Active Mirror-Image DNA-Ligase Made of D-Amino Acids. Cell Chemical Biology. PMID 30880154 DOI: 10.1016/J.Chembiol.2019.02.008  0.349
2019 Cistrone PA, Bird MJ, Flood DT, Silvestri AP, Hintzen JCJ, Thompson DA, Dawson PE. Native Chemical Ligation of Peptides and Proteins. Current Protocols in Chemical Biology. e61. PMID 30645048 DOI: 10.1002/Cpch.61  0.679
2019 Won Y, Pagar AD, Patil MD, Dawson PE, Yun H. Recent Advances in Enzyme Engineering through Incorporation of Unnatural Amino Acids Biotechnology and Bioprocess Engineering. 24: 592-604. DOI: 10.1007/S12257-019-0163-X  0.302
2018 Palomo V, Cistrone PA, Zhan N, Palui G, Mattoussi H, Dawson PE. Efficient Assembly of Quantum Dots with Homogenous Glycans Derived from Natural N-linked Glycoproteins. Bioconjugate Chemistry. PMID 30063825 DOI: 10.1021/Acs.Bioconjchem.8B00477  0.344
2018 Flood DT, Hintzen JCJ, Bird MJ, Cistrone PA, Chen JS, Dawson PE. Leveraging the Knorr Pyrazole Synthesis for the Facile Generation of Thioester Surrogates for use in NCL. Angewandte Chemie (International Ed. in English). PMID 29908104 DOI: 10.1002/Anie.201805191  0.481
2018 Flood DT, Yan NL, Dawson PE. Post Translational Backbone Engineering through Selenomethionine Mediated Incorporation of Freidinger Lactams. Angewandte Chemie (International Ed. in English). PMID 29797386 DOI: 10.1002/Anie.201804885  0.475
2018 Bird MJ, Silvestri AP, Dawson PE. Expedient on-resin synthesis of peptidic benzimidazoles. Bioorganic & Medicinal Chemistry Letters. PMID 29739642 DOI: 10.1016/J.Bmcl.2018.04.062  0.406
2018 Lee TC, Moran CR, Cistrone PA, Dawson PE, Deniz AA. Site-Specific Three-Color Labeling of α-Synuclein via Conjugation to Uniquely Reactive Cysteines during Assembly by Native Chemical Ligation. Cell Chemical Biology. PMID 29681525 DOI: 10.1016/J.Chembiol.2018.03.009  0.404
2018 Cistrone PA, Silvestri AP, Hintzen JCJ, Dawson PE. Rigid Peptide Macrocycles via On-Resin Glaser Stapling. Chembiochem : a European Journal of Chemical Biology. PMID 29516601 DOI: 10.1002/Cbic.201800121  0.424
2017 Liew SK, Holownia A, Diaz DB, Cistrone PA, Dawson PE, Yudin AK. Borylated oximes: versatile building blocks for organic synthesis. Chemical Communications (Cambridge, England). PMID 28959806 DOI: 10.1039/C7Cc06579E  0.335
2017 Breger JC, Muttenthaler M, Delehanty JB, Thompson DA, Oh E, Susumu K, Deschamps JR, Anderson GP, Field LD, Walper SA, Dawson PE, Medintz IL. Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery. Nanoscale. PMID 28703833 DOI: 10.1039/C7Nr03362A  0.619
2017 Silvestri AP, Dawson PE. Base-catalyzed diastereoselective trimerization of trifluoroacetone. Organic & Biomolecular Chemistry. PMID 28594047 DOI: 10.1039/C7Ob01094J  0.326
2017 Adhikary R, Tan YX, Liu J, Zimmermann J, Holcomb M, Yvellez C, Dawson PE, Romesberg FE. Conformational Heterogeneity and DNA Recognition by the Morphogen Bicoid. Biochemistry. PMID 28547993 DOI: 10.1021/Acs.Biochem.7B00255  0.355
2017 Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, L Efros A, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, et al. Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of In Vitro and In Vivo Cellular Membrane Potential. Acs Nano. PMID 28514167 DOI: 10.1021/Acsnano.7B00954  0.386
2017 Matthews ML, He L, Horning BD, Olson EJ, Correia BE, Yates JR, Dawson PE, Cravatt BF. Chemoproteomic profiling and discovery of protein electrophiles in human cells. Nature Chemistry. 9: 234-243. PMID 28221344 DOI: 10.1038/Nchem.2645  0.417
2016 Algar WR, Khachatrian A, Melinger JS, Huston AL, Stewart MH, Susumu K, Blanco-Canosa JB, Oh E, Dawson PE, Medintz IL. Concurrent Modulation of Quantum Dot Photoluminescence Using a Combination of Charge Transfer and Förster Resonance Energy Transfer: Competitive Quenching and Multiplexed Biosensing Modality. Journal of the American Chemical Society. PMID 28009161 DOI: 10.1021/Jacs.6B11042  0.324
2016 Olson EJ, Lechtenberg BC, Zhao C, Rubio de la Torre E, Lamberto I, Riedl SJ, Dawson PE, Pasquale EB. Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability. Acs Medicinal Chemistry Letters. 7: 841-6. PMID 27660688 DOI: 10.1021/Acsmedchemlett.6B00132  0.397
2016 Getz T, Qin J, Medintz IL, Delehanty JB, Susumo K, Dawson PE, Dawson G. Quantum dot mediated delivery of siRNA to inhibit sphingomyelinase activities in brain-derived cells. Journal of Neurochemistry. PMID 27622309 DOI: 10.1111/Jnc.13841  0.385
2016 Palomo V, Díaz SA, Stewart MH, Susumu K, Medintz IL, Dawson PE. 3,4-Dihydroxyphenylalanine Peptides as Non-Perturbative Quantum Dot Sensors of Aminopeptidase. Acs Nano. PMID 27206058 DOI: 10.1021/Acsnano.6B01682  0.438
2016 Agten SM, Dawson PE, Hackeng TM. Oxime conjugation in protein chemistry: from carbonyl incorporation to nucleophilic catalysis. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 27006095 DOI: 10.1002/Psc.2874  0.482
2016 Thompson DA, Ng R, Dawson PE. Arginine selective reagents for ligation to peptides and proteins. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 27005702 DOI: 10.1002/Psc.2867  0.664
2016 Cistrone PA, Dawson PE. Click-Based Libraries of SFTI-1 Peptides: New Methods Using Reversed-Phase Silica. Acs Combinatorial Science. PMID 26914614 DOI: 10.1021/Acscombsci.5B00195  0.446
2016 Reichart TM, Baksh MM, Rhee JK, Fiedler JD, Sligar SG, Finn MG, Zwick MB, Dawson PE. Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding. Angewandte Chemie (International Ed. in English). PMID 26799917 DOI: 10.1002/Anie.201508421  0.329
2016 Breger J, Delehanty J, Susumu K, Anderson G, Muttenhaler M, Dawson P, Medintz I. The influence of cell penetrating peptide branching on cellular uptake of QDs Proceedings of Spie. 9722. DOI: 10.1117/12.2207311  0.415
2015 Weidmann J, Dimitrijević E, Hoheisel JD, Dawson PE. Boc-SPPS: Compatible Linker for the Synthesis of Peptide o-Aminoanilides. Organic Letters. PMID 26702477 DOI: 10.1021/Acs.Orglett.5B03111  0.402
2015 Zhang H, Sturchler E, Zhu J, Nieto A, Cistrone PA, Xie J, He L, Yea K, Jones T, Turn R, Di Stefano PS, Griffin PR, Dawson PE, McDonald PH, Lerner RA. Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects. Nature Communications. 6: 8918. PMID 26621478 DOI: 10.1038/Ncomms9918  0.331
2015 Adhikary R, Zimmermann J, Dawson PE, Romesberg FE. Temperature Dependence of CN and SCN IR Absorptions Facilitates Their Interpretation and Use as Probes of Proteins. Analytical Chemistry. PMID 26523838 DOI: 10.1021/Acs.Analchem.5B03437  0.327
2015 Assem N, Ferreira DJ, Wolan DW, Dawson PE. Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angewandte Chemie (International Ed. in English). PMID 26096515 DOI: 10.1002/Anie.201502607  0.46
2015 Muttenthaler M, Albericio F, Dawson PE. Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis. Nature Protocols. 10: 1067-83. PMID 26086408 DOI: 10.1038/Nprot.2015.061  0.43
2015 Blanco-Canosa JB, Nardone B, Albericio F, Dawson PE. Chemical Protein Synthesis Using a Second-Generation N-Acylurea Linker for the Preparation of Peptide-Thioester Precursors. Journal of the American Chemical Society. 137: 7197-209. PMID 25978693 DOI: 10.1021/Jacs.5B03504  0.481
2015 Agarwal R, Domowicz MS, Schwartz NB, Henry J, Medintz I, Delehanty JB, Stewart MH, Susumu K, Huston AL, Deschamps JR, Dawson PE, Palomo V, Dawson G. Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain. Acs Chemical Neuroscience. 6: 494-504. PMID 25688887 DOI: 10.1021/Acschemneuro.5B00022  0.338
2015 Aldeek F, Hawkins D, Palomo V, Safi M, Palui G, Dawson PE, Alabugin I, Mattoussi H. UV and sunlight driven photoligation of quantum dots: understanding the photochemical transformation of the ligands. Journal of the American Chemical Society. 137: 2704-14. PMID 25612193 DOI: 10.1021/Ja512802X  0.339
2015 Breger J, Delehanty JB, Boeneman Gemmill K, Field LD, Blanco-Canosa JB, Dawson PE, Huston AL, Medintz IL. Membrane-targeting peptides for nanoparticle-facilitated cellular imaging and analysis Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9338. DOI: 10.1117/12.2077026  0.312
2015 Gemmill KB, Dĺaz SA, Blanco-Canosa JB, Deschamps JR, Pons T, Liu HW, Deniz A, Melinger J, Oh E, Susumu K, Stewart MH, Hastman DA, North SH, Delehanty JB, Dawson PE, et al. Examining the Polyproline Nanoscopic Ruler in the Context of Quantum Dots Chemistry of Materials. 27: 6222-6237. DOI: 10.1021/Acs.Chemmater.5B03181  0.427
2014 Lamberto I, Lechtenberg BC, Olson EJ, Mace PD, Dawson PE, Riedl SJ, Pasquale EB. Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor. Acs Chemical Biology. 9: 2787-95. PMID 25268696 DOI: 10.1021/Cb500677X  0.447
2014 Adhikary R, Zimmermann J, Liu J, Forrest RP, Janicki TD, Dawson PE, Corcelli SA, Romesberg FE. Evidence of an unusual N-H···N hydrogen bond in proteins. Journal of the American Chemical Society. 136: 13474-7. PMID 25226114 DOI: 10.1021/Ja503107H  0.354
2014 Scott AM, Algar WR, Stewart MH, Trammell SA, Blanco-Canosa JB, Dawson PE, Deschamps JR, Goswami R, Oh E, Huston AL, Medintz IL. Probing the Quenching of Quantum Dot Photoluminescence by Peptide-Labeled Ruthenium(II) Complexes. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 118: 9239-9250. PMID 24817922 DOI: 10.1021/Jp501039W  0.354
2014 Thompson DA, Evans EG, Kasza T, Millhauser GL, Dawson PE. Adapter reagents for protein site specific dye labeling. Biopolymers. 102: 273-9. PMID 24599728 DOI: 10.1002/Bip.22481  0.699
2014 Adhikary R, Zimmermann J, Dawson PE, Romesberg FE. IR probes of protein microenvironments: utility and potential for perturbation. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 15: 849-53. PMID 24519759 DOI: 10.1002/Cphc.201400017  0.382
2014 Wendeler M, Grinberg L, Wang X, Dawson PE, Baca M. Enhanced catalysis of oxime-based bioconjugations by substituted anilines. Bioconjugate Chemistry. 25: 93-101. PMID 24320725 DOI: 10.1021/Bc400380F  0.338
2014 Delehanty JB, Blanco-Canosa JB, Bradburne CE, Susumu K, Stewart MH, Prasuhn DE, Dawson PE, Medintz IL. Controlling the intracellular fate of nano-bioconjugates: pathways for realizing nanoparticle-mediated theranostics Proceedings of Spie. 9166. DOI: 10.1117/12.2064372  0.341
2014 Blanco-Canosa JB, Wu M, Susumu K, Petryayeva E, Jennings TL, Dawson PE, Algar WR, Medintz IL. Recent progress in the bioconjugation of quantum dots Coordination Chemistry Reviews. 263: 101-137. DOI: 10.1016/J.Ccr.2013.08.030  0.377
2014 Culhane JC, Dawson PE. Peptide pharmaceuticals: Modifications to the peptide backbone that enhance stability and targeting Chimica Oggi/Chemistry Today. 32: 17-20.  0.301
2013 Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, et al. Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences of the United States of America. 110: 21183-8. PMID 24248349 DOI: 10.1073/Pnas.1311183110  0.42
2013 Stewart MH, Huston AL, Scott AM, Oh E, Algar WR, Deschamps JR, Susumu K, Jain V, Prasuhn DE, Blanco-Canosa J, Dawson PE, Medintz IL. Competition between Förster resonance energy transfer and electron transfer in stoichiometrically assembled semiconductor quantum dot-fullerene conjugates. Acs Nano. 7: 9489-505. PMID 24128175 DOI: 10.1021/Nn403872X  0.368
2013 Algar WR, Blanco-Canosa JB, Manthe RL, Susumu K, Stewart MH, Dawson PE, Medintz IL. Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates. Methods in Molecular Biology (Clifton, N.J.). 1025: 47-73. PMID 23918329 DOI: 10.1007/978-1-62703-462-3_5  0.466
2013 Bradburne CE, Delehanty JB, Boeneman Gemmill K, Mei BC, Mattoussi H, Susumu K, Blanco-Canosa JB, Dawson PE, Medintz IL. Cytotoxicity of quantum dots used for in vitro cellular labeling: role of QD surface ligand, delivery modality, cell type, and direct comparison to organic fluorophores. Bioconjugate Chemistry. 24: 1570-83. PMID 23879393 DOI: 10.1021/Bc4001917  0.342
2013 Adhikary R, Zimmermann J, Liu J, Dawson PE, Romesberg FE. Experimental characterization of electrostatic and conformational heterogeneity in an SH3 domain. The Journal of Physical Chemistry. B. 117: 13082-9. PMID 23834285 DOI: 10.1021/Jp402772X  0.406
2013 Delehanty JB, Blanco-Canosa JB, Bradburne CE, Susumu K, Stewart MH, Prasuhn DE, Dawson PE, Medintz IL. Site-specific cellular delivery of quantum dots with chemoselectively-assembled modular peptides. Chemical Communications (Cambridge, England). 49: 7878-80. PMID 23759873 DOI: 10.1039/C3Cc42781A  0.392
2013 Gemmill KB, Muttenthaler M, Delehanty JB, Stewart MH, Susumu K, Dawson PE, Medintz IL. Evaluation of diverse peptidyl motifs for cellular delivery of semiconductor quantum dots. Analytical and Bioanalytical Chemistry. 405: 6145-54. PMID 23732866 DOI: 10.1007/S00216-013-6982-2  0.443
2013 Boeneman K, Delehanty JB, Blanco-Canosa JB, Susumu K, Stewart MH, Oh E, Huston AL, Dawson G, Ingale S, Walters R, Domowicz M, Deschamps JR, Algar WR, Dimaggio S, Manono J, ... ... Dawson PE, et al. Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials. Acs Nano. 7: 3778-96. PMID 23710591 DOI: 10.1021/Nn400702R  0.655
2013 Gemmill KB, Muttenthaler M, Delehanty J, Deschamps J, Susumu K, Stewart M, Dawson P, Huston A, Medintz I. Peptide-mediated cellular delivery of semiconductor quantum dots Proceedings of Spie - the International Society For Optical Engineering. 8723. DOI: 10.1117/12.2015446  0.434
2012 Walters R, Kraig RP, Medintz I, Delehanty JB, Stewart MH, Susumu K, Huston AL, Dawson PE, Dawson G. Nanoparticle targeting to neurons in a rat hippocampal slice culture model. Asn Neuro. 4: 383-92. PMID 22973864 DOI: 10.1042/An20120042  0.35
2012 Algar WR, Malonoski A, Deschamps JR, Blanco-Canosa JB, Susumu K, Stewart MH, Johnson BJ, Dawson PE, Medintz IL. Proteolytic activity at quantum dot-conjugates: kinetic analysis reveals enhanced enzyme activity and localized interfacial "hopping". Nano Letters. 12: 3793-802. PMID 22731798 DOI: 10.1021/Nl301727K  0.343
2012 Stewart MH, Huston AL, Scott AM, Efros AL, Melinger JS, Gemmill KB, Trammell SA, Blanco-Canosa JB, Dawson PE, Medintz IL. Complex Förster energy transfer interactions between semiconductor quantum dots and a redox-active osmium assembly. Acs Nano. 6: 5330-47. PMID 22671940 DOI: 10.1021/Nn301177H  0.357
2012 Wu Z, Chen K, Yildiz I, Dirksen A, Fischer R, Dawson PE, Steinmetz NF. Development of viral nanoparticles for efficient intracellular delivery. Nanoscale. 4: 3567-76. PMID 22508503 DOI: 10.1039/C2Nr30366C  0.319
2012 Algar WR, Wegner D, Huston AL, Blanco-Canosa JB, Stewart MH, Armstrong A, Dawson PE, Hildebrandt N, Medintz IL. Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing. Journal of the American Chemical Society. 134: 1876-91. PMID 22220737 DOI: 10.1021/Ja210162F  0.309
2012 Reichart T, Baksh M, Zwick M, Finn M, Dawson P. Analysis of gp41 epitopes in model viral membranes to study HIV-1 neutralization Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P105  0.309
2012 Gemmill KB, Delehanty JB, Stewart MH, Susumu K, Blanco-Canosa JB, Dawson PE, Huston A, Medintz I. Further progress in cytosolic cellular delivery of quantum dots Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8232. DOI: 10.1117/12.906801  0.428
2011 Zimmermann J, Thielges MC, Seo YJ, Dawson PE, Romesberg FE. Cyano groups as probes of protein microenvironments and dynamics. Angewandte Chemie (International Ed. in English). 50: 8333-7. PMID 21780257 DOI: 10.1002/Anie.201101016  0.3
2011 Oh E, Delehanty JB, Sapsford KE, Susumu K, Goswami R, Blanco-Canosa JB, Dawson PE, Granek J, Shoff M, Zhang Q, Goering PL, Huston A, Medintz IL. Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size. Acs Nano. 5: 6434-48. PMID 21774456 DOI: 10.1021/Nn201624C  0.38
2011 Delehanty JB, Bradburne CE, Susumu K, Boeneman K, Mei BC, Farrell D, Blanco-Canosa JB, Dawson PE, Mattoussi H, Medintz IL. Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques. Journal of the American Chemical Society. 133: 10482-9. PMID 21627173 DOI: 10.1021/Ja200555Z  0.396
2011 Susumu K, Oh E, Delehanty JB, Blanco-Canosa JB, Johnson BJ, Jain V, Hervey WJ, Algar WR, Boeneman K, Dawson PE, Medintz IL. Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles. Journal of the American Chemical Society. 133: 9480-96. PMID 21612225 DOI: 10.1021/Ja201919S  0.341
2011 Ingale S, Dawson PE. On resin side-chain cyclization of complex peptides using CuAAC. Organic Letters. 13: 2822-5. PMID 21553819 DOI: 10.1021/Ol200775H  0.434
2011 Venter PA, Dirksen A, Thomas D, Manchester M, Dawson PE, Schneemann A. Multivalent display of proteins on viral nanoparticles using molecular recognition and chemical ligation strategies. Biomacromolecules. 12: 2293-301. PMID 21545187 DOI: 10.1021/Bm200369E  0.377
2011 Schneider J, Dawson P. 22(nd) American Peptide Symposium Biopolymers. 96: iii. PMID 21509741 DOI: 10.1002/Bip.21580  0.381
2011 Sapsford KE, Granek J, Deschamps JR, Boeneman K, Blanco-Canosa JB, Dawson PE, Susumu K, Stewart MH, Medintz IL. Monitoring botulinum neurotoxin a activity with peptide-functionalized quantum dot resonance energy transfer sensors. Acs Nano. 5: 2687-99. PMID 21361387 DOI: 10.1021/Nn102997B  0.436
2011 Zimmermann J, Thielges MC, Yu W, Dawson PE, Romesberg FE. Carbon-deuterium bonds as site-specific and nonperturbative probes for time-resolved studies of protein dynamics and folding Journal of Physical Chemistry Letters. 2: 412-416. DOI: 10.1021/Jz200012H  0.368
2011 Dawson PE. Native chemical ligation combined with desulfurization and deselenization: A general strategy for chemical protein synthesis Israel Journal of Chemistry. 51: 862-867. DOI: 10.1002/Ijch.201100128  0.503
2011 Brik A, Dawson PE, Kent SBH. Guest editorial: Chemical protein synthesis Israel Journal of Chemistry. 51: 852-853. DOI: 10.1002/Ijch.201100087  0.391
2010 Boeneman K, Prasuhn DE, Blanco-Canosa JB, Dawson PE, Melinger JS, Ancona M, Stewart MH, Susumu K, Huston A, Medintz IL. Self-assembled quantum dot-sensitized multivalent DNA photonic wires. Journal of the American Chemical Society. 132: 18177-90. PMID 21141858 DOI: 10.1021/Ja106465X  0.319
2010 Ingale S, Gach JS, Zwick MB, Dawson PE. Synthesis and analysis of the membrane proximal external region epitopes of HIV-1. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 716-22. PMID 21104968 DOI: 10.1002/Psc.1325  0.336
2010 Prasuhn DE, Feltz A, Blanco-Canosa JB, Susumu K, Stewart MH, Mei BC, Yakovlev AV, Loukov C, Mallet JM, Oheim M, Dawson PE, Medintz IL. Quantum dot peptide biosensors for monitoring caspase 3 proteolysis and calcium ions. Acs Nano. 4: 5487-97. PMID 20822159 DOI: 10.1021/Nn1016132  0.414
2010 Metanis N, Keinan E, Dawson PE. Traceless ligation of cysteine peptides using selective deselenization. Angewandte Chemie (International Ed. in English). 49: 7049-53. PMID 20715234 DOI: 10.1002/Anie.201001900  0.735
2010 Blanco-Canosa JB, Medintz IL, Farrell D, Mattoussi H, Dawson PE. Rapid covalent ligation of fluorescent peptides to water solubilized quantum dots. Journal of the American Chemical Society. 132: 10027-33. PMID 20597509 DOI: 10.1021/Ja910988D  0.403
2010 Dawson PE. Synthetic protein chemistry. Editorial. Biopolymers. 94: iii. PMID 20593465 DOI: 10.1002/Bip.21505  0.396
2010 Tiefenbrunn TK, Blanco-Canosa J, Dawson PE. Alternative chemistries for the synthesis of thrombospondin-1 type 1 repeats. Biopolymers. 94: 405-13. PMID 20593462 DOI: 10.1002/Bip.21486  0.483
2010 Van de Vijver P, Suylen D, Dirksen A, Dawson PE, Hackeng TM. Nepsilon-(thiaprolyl)-lysine as a handle for site-specific protein conjugation. Biopolymers. 94: 465-74. PMID 20593461 DOI: 10.1002/Bip.21485  0.48
2010 Stewart MH, Susumu K, Mei BC, Medintz IL, Delehanty JB, Blanco-Canosa JB, Dawson PE, Mattoussi H. Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions. Journal of the American Chemical Society. 132: 9804-13. PMID 20578776 DOI: 10.1021/Ja102898D  0.342
2010 Delehanty JB, Bradburne CE, Boeneman K, Susumu K, Farrell D, Mei BC, Blanco-Canosa JB, Dawson G, Dawson PE, Mattoussi H, Medintz IL. Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2: 265-77. PMID 20535418 DOI: 10.1039/C0Ib00002G  0.395
2010 Erlich LA, Kumar KS, Haj-Yahya M, Dawson PE, Brik A. N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester. Organic & Biomolecular Chemistry. 8: 2392-6. PMID 20448897 DOI: 10.1039/C000332H  0.479
2010 Dawson G, Schroeder C, Dawson PE. Palmitoyl:protein thioesterase (PPT1) inhibitors can act as pharmacological chaperones in infantile Batten disease. Biochemical and Biophysical Research Communications. 395: 66-9. PMID 20346914 DOI: 10.1016/J.Bbrc.2010.03.137  0.324
2010 Dirksen A, Yegneswaran S, Dawson PE. Bisaryl hydrazones as exchangeable biocompatible linkers. Angewandte Chemie (International Ed. in English). 49: 2023-7. PMID 20183838 DOI: 10.1002/Anie.200906756  0.416
2010 Prasuhn DE, Blanco-Canosa JB, Vora GJ, Delehanty JB, Susumu K, Mei BC, Dawson PE, Medintz IL. Combining chemoselective ligation with polyhistidine-driven self-assembly for the modular display of biomolecules on quantum dots. Acs Nano. 4: 267-78. PMID 20099912 DOI: 10.1021/Nn901393V  0.442
2010 Tiefenbrunn TK, Dawson PE. Chemoselective ligation techniques: modern applications of time-honored chemistry. Biopolymers. 94: 95-106. PMID 20091876 DOI: 10.1002/Bip.21337  0.359
2010 Prasuhn DE, Deschamps JR, Susumu K, Stewart MH, Boeneman K, Blanco-Canosa JB, Dawson PE, Medintz IL. Polyvalent display and packing of peptides and proteins on semiconductor quantum dots: predicted versus experimental results. Small (Weinheim An Der Bergstrasse, Germany). 6: 555-64. PMID 20077423 DOI: 10.1002/Smll.200901845  0.476
2010 Sapsford KE, Blanco-Canosa JB, Dawson PE, Medintz IL. Detection of HIV-1 specific monoclonal antibodies using enhancement of dye-labeled antigenic peptides. Bioconjugate Chemistry. 21: 393-8. PMID 20058910 DOI: 10.1021/Bc9003712  0.375
2010 Shekhter T, Metanis N, Dawson PE, Keinan E. A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3. Molecular Biosystems. 6: 241-8. PMID 20024086 DOI: 10.1039/B912753D  0.678
2010 Delehanty JB, Bradburne CE, Boeneman KE, Medintz IL, Farrell D, Pons T, Mei BC, Blanco-Canosa JB, Dawson PE, Mattoussi H. Delivery of quantum dot bioconjugates to the cellular cytosol: Release from the endolysosomal system Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7575. DOI: 10.1117/12.842434  0.405
2010 MUIR TW, DAWSON PE, KENT SBH. ChemInform Abstract: Protein Synthesis by Chemical Ligation of Unprotected Peptides in Aqueous Solution Cheminform. 29: no-no. DOI: 10.1002/chin.199812274  0.343
2009 Vanacore R, Ham AJ, Voehler M, Sanders CR, Conrads TP, Veenstra TD, Sharpless KB, Dawson PE, Hudson BG. A sulfilimine bond identified in collagen IV. Science (New York, N.Y.). 325: 1230-4. PMID 19729652 DOI: 10.1126/Science.1176811  0.302
2009 Pejchal R, Gach JS, Brunel FM, Cardoso RM, Stanfield RL, Dawson PE, Burton DR, Zwick MB, Wilson IA. A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. Journal of Virology. 83: 8451-62. PMID 19515770 DOI: 10.1128/Jvi.00685-09  0.337
2009 Medintz IL, Farrell D, Susumu K, Trammell SA, Deschamps JR, Brunel FM, Dawson PE, Mattoussi H. Multiplex charge-transfer interactions between quantum dots and peptide-bridged ruthenium complexes. Analytical Chemistry. 81: 4831-9. PMID 19445483 DOI: 10.1021/Ac900412J  0.37
2009 Tiefenbrunn TK, Dawson PE. Chemical synthesis and biotinylation of the thrombospondin domain TSR2. Protein Science : a Publication of the Protein Society. 18: 970-9. PMID 19384999 DOI: 10.1002/Pro.107  0.404
2009 Cremeens ME, Zimmermann J, Yu W, Dawson PE, Romesberg FE. Direct observation of structural heterogeneity in a beta-sheet. Journal of the American Chemical Society. 131: 5726-7. PMID 19351132 DOI: 10.1021/Ja900505E  0.333
2009 Thielges MC, Zimmermann J, Dawson PE, Romesberg FE. The determinants of stability and folding in evolutionarily diverged cytochromes c. Journal of Molecular Biology. 388: 159-67. PMID 19268474 DOI: 10.1016/J.Jmb.2009.02.059  0.387
2008 Dirksen A, Dawson PE. Expanding the scope of chemoselective peptide ligations in chemical biology. Current Opinion in Chemical Biology. 12: 760-6. PMID 19058994 DOI: 10.1016/J.Cbpa.2008.10.009  0.474
2008 Dirksen A, Dawson PE. Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling. Bioconjugate Chemistry. 19: 2543-8. PMID 19053314 DOI: 10.1021/Bc800310P  0.436
2008 Medintz IL, Pons T, Trammell SA, Grimes AF, English DS, Blanco-Canosa JB, Dawson PE, Mattoussi H. Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge. Journal of the American Chemical Society. 130: 16745-56. PMID 19049466 DOI: 10.1021/Ja805456X  0.327
2008 Yegneswaran S, Hackeng TM, Dawson PE, Griffin JH. The thrombin-sensitive region of protein S mediates phospholipid-dependent interaction with factor Xa. The Journal of Biological Chemistry. 283: 33046-52. PMID 18784085 DOI: 10.1074/Jbc.M806527200  0.364
2008 Burlina F, Dixson DD, Doyle RP, Chassaing G, Boddy CN, Dawson P, Offer J. Orthogonal ligation: a three piece assembly of a PNA-peptide-PNA conjugate. Chemical Communications (Cambridge, England). 2785-7. PMID 18688310 DOI: 10.1039/B801242C  0.434
2008 Medintz IL, Pons T, Delehanty JB, Susumu K, Brunel FM, Dawson PE, Mattoussi H. Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides. Bioconjugate Chemistry. 19: 1785-95. PMID 18681468 DOI: 10.1021/Bc800089R  0.454
2008 Blanco-Canosa JB, Dawson PE. An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation. Angewandte Chemie (International Ed. in English). 47: 6851-5. PMID 18651678 DOI: 10.1002/Anie.200705471  0.483
2008 Yamamoto N, Tanabe Y, Okamoto R, Dawson PE, Kajihara Y. Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies. Journal of the American Chemical Society. 130: 501-10. PMID 18085777 DOI: 10.1021/Ja072543F  0.47
2008 Delehanty JB, Bradburne CE, Medintz IL, Farrell D, Pons T, Brunel FM, Dawson PE, Mattoussi H. Specific cellular delivery and intracellular fate of quantum dot-peptide and quantum dot-polymer nanoassemblies Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6866. DOI: 10.1117/12.763760  0.385
2008 Medintz IL, Pons T, Delehanty JB, Susumu K, Dawson PE, Mattoussi H. Assembly and intracellular delivery of quantum dot - Fluorescent protein bioconjugates Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6866. DOI: 10.1117/12.763702  0.363
2007 Yegneswaran S, Tiefenbrunn TK, Fernández JA, Dawson PE. Manipulation of thrombin exosite I, by ligand-directed covalent modification. Journal of Thrombosis and Haemostasis : Jth. 5: 2062-9. PMID 17883702 DOI: 10.1111/J.1538-7836.2007.02712.X  0.446
2007 Xu Y, Hixon MS, Dawson PE, Janda KD. Development of a FRET assay for monitoring of HIV gp41 core disruption. The Journal of Organic Chemistry. 72: 6700-7. PMID 17685571 DOI: 10.1021/Jo070836L  0.37
2007 Blankenship JW, Dawson PE. Threading a peptide through a peptide: protein loops, rotaxanes, and knots. Protein Science : a Publication of the Protein Society. 16: 1249-56. PMID 17567748 DOI: 10.1110/Ps.062673207  0.73
2007 Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. Journal of Virology. 81: 4033-43. PMID 17287272 DOI: 10.1128/Jvi.02588-06  0.32
2007 Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. Journal of Molecular Biology. 365: 1533-44. PMID 17125793 DOI: 10.1016/J.Jmb.2006.10.088  0.415
2007 Delehanty JB, Medintz IL, Pons T, Dawson PE, Brunel FM, Mattoussi H. Selective cellular delivery of self-assembled quantum dot-peptide bioconjugates Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6448. DOI: 10.1117/12.700768  0.414
2007 Sapsford KE, Pons T, Medintz IL, Higashiya S, Brunel FM, Dawson PE, Mattoussi H. Kinetics of metal-affinity driven self-assembly between proteins or peptides and CdSe-ZnS quantum dots Journal of Physical Chemistry C. 111: 11528-11538. DOI: 10.1021/Jp073550T  0.323
2006 Metanis N, Keinan E, Dawson PE. Synthetic seleno-glutaredoxin 3 analogues are highly reducing oxidoreductases with enhanced catalytic efficiency. Journal of the American Chemical Society. 128: 16684-91. PMID 17177418 DOI: 10.1021/Ja0661414  0.674
2006 Dirksen A, Dirksen S, Hackeng TM, Dawson PE. Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry. Journal of the American Chemical Society. 128: 15602-3. PMID 17147365 DOI: 10.1021/Ja067189K  0.377
2006 Sagle LB, Zimmermann J, Dawson PE, Romesberg FE. Direct and high resolution characterization of cytochrome c equilibrium folding. Journal of the American Chemical Society. 128: 14232-3. PMID 17076477 DOI: 10.1021/Ja065179D  0.313
2006 Dirksen A, Hackeng TM, Dawson PE. Nucleophilic catalysis of oxime ligation. Angewandte Chemie (International Ed. in English). 45: 7581-4. PMID 17051631 DOI: 10.1002/Anie.200602877  0.344
2006 Delehanty JB, Medintz IL, Pons T, Brunel FM, Dawson PE, Mattoussi H. Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery. Bioconjugate Chemistry. 17: 920-7. PMID 16848398 DOI: 10.1021/Bc060044I  0.438
2006 Medintz IL, Clapp AR, Brunel FM, Tiefenbrunn T, Uyeda HT, Chang EL, Deschamps JR, Dawson PE, Mattoussi H. Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates. Nature Materials. 5: 581-9. PMID 16799548 DOI: 10.1038/Nmat1676  0.41
2006 Sagle LB, Zimmermann J, Matsuda S, Dawson PE, Romesberg FE. Redox-coupled dynamics and folding in cytochrome c. Journal of the American Chemical Society. 128: 7909-15. PMID 16771505 DOI: 10.1021/Ja060851S  0.362
2006 Brunel FM, Zwick MB, Cardoso RM, Nelson JD, Wilson IA, Burton DR, Dawson PE. Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody. Journal of Virology. 80: 1680-7. PMID 16439525 DOI: 10.1128/Jvi.80.4.1680-1687.2006  0.401
2006 Yamamoto N, Takayanagi A, Sakakibara T, Dawson PE, Kajihara Y. Highly efficient synthesis of sialylglycopeptides overcoming unexpected aspartimide formation during activation of Fmoc- Asn(undecadisialyloligosaccharide)-OH Tetrahedron Letters. 47: 1341-1346. DOI: 10.1016/J.Tetlet.2005.12.064  0.42
2005 Brunel FM, Dawson PE. Synthesis of constrained helical peptides by thioether ligation: application to analogs of gp41. Chemical Communications (Cambridge, England). 2552-4. PMID 15900323 DOI: 10.1039/B419015G  0.433
2005 Metanis N, Keinan E, Dawson PE. A designed synthetic analogue of 4-OT is specific for a non-natural substrate. Journal of the American Chemical Society. 127: 5862-8. PMID 15839684 DOI: 10.1021/Ja050110B  0.672
2005 McNulty JC, Jackson PJ, Thompson DA, Chai B, Gantz I, Barsh GS, Dawson PE, Millhauser GL. Structures of the agouti signaling protein. Journal of Molecular Biology. 346: 1059-70. PMID 15701517 DOI: 10.1016/J.Jmb.2004.12.030  0.73
2005 Yegneswaran S, Tiefenbrunn T, Fernandez JA, Dawson PE. Exosite-Specific Inhibition of Thrombin Using Photo-Crosslinked Fluorescent Reporter Peptides. Blood. 106: 1954-1954. DOI: 10.1182/Blood.V106.11.1954.1954  0.493
2004 Deechongkit S, Dawson PE, Kelly JW. Toward assessing the position-dependent contributions of backbone hydrogen bonding to beta-sheet folding thermodynamics employing amide-to-ester perturbations. Journal of the American Chemical Society. 126: 16762-71. PMID 15612714 DOI: 10.1021/Ja045934S  0.302
2004 Metanis N, Brik A, Dawson PE, Keinan E. Electrostatic interactions dominate the catalytic contribution of arg39 in 4-oxalocrotonate tautomerase. Journal of the American Chemical Society. 126: 12726-7. PMID 15469238 DOI: 10.1021/Ja0463841  0.656
2004 Deechongkit S, Nguyen H, Powers ET, Dawson PE, Gruebele M, Kelly JW. Context-dependent contributions of backbone hydrogen bonding to beta-sheet folding energetics. Nature. 430: 101-5. PMID 15229605 DOI: 10.1038/Nature02611  0.367
2004 Kamikubo Y, De Guzman R, Kroon G, Curriden S, Neels JG, Churchill MJ, Dawson P, OÅ‚dziej S, Jagielska A, Scheraga HA, Loskutoff DJ, Dyson HJ. Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin. Biochemistry. 43: 6519-34. PMID 15157085 DOI: 10.1021/Bi049647C  0.364
2004 Marinzi C, Offer J, Longhi R, Dawson PE. An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications. Bioorganic & Medicinal Chemistry. 12: 2749-57. PMID 15110856 DOI: 10.1016/J.Bmc.2004.02.039  0.467
2004 Sagle LB, Zimmermann J, Dawson PE, Romesberg FE. A high-resolution probe of protein folding. Journal of the American Chemical Society. 126: 3384-5. PMID 15025440 DOI: 10.1021/Ja049890Z  0.414
2003 Bayro MJ, Mukhopadhyay J, Swapna GV, Huang JY, Ma LC, Sineva E, Dawson PE, Montelione GT, Ebright RH. Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot. Journal of the American Chemical Society. 125: 12382-3. PMID 14531661 DOI: 10.1021/Ja036677E  0.384
2003 Blankenship JW, Dawson PE. Thermodynamics of a designed protein catenane. Journal of Molecular Biology. 327: 537-48. PMID 12628256 DOI: 10.1016/S0022-2836(03)00115-3  0.697
2002 Blankenship JW, Balambika R, Dawson PE. Probing backbone hydrogen bonds in the hydrophobic core of GCN4. Biochemistry. 41: 15676-84. PMID 12501196 DOI: 10.1021/Bi026862P  0.682
2002 Brik A, Dawson PE, Keinan E. The product of the natural reaction catalyzed by 4-oxalocrotonate tautomerase becomes an affinity label of its mutant. Bioorganic & Medicinal Chemistry. 10: 3891-7. PMID 12413840 DOI: 10.1016/S0968-0896(02)00385-1  0.344
2002 Brik A, D'Souza LJ, Keinan E, Grynszpan F, Dawson PE. Mutants of 4-oxalocrotonate tautomerase catalyze the decarboxylation of oxaloacetate through an imine mechanism. Chembiochem : a European Journal of Chemical Biology. 3: 845-51. PMID 12210985 DOI: 10.1002/1439-7633(20020902)3:9<845::Aid-Cbic845>3.0.Co;2-2  0.302
2002 Marx PF, Dawson PE, Bouma BN, Meijers JCM. Plasmin-mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor Biochemistry. 41: 6688-6696. PMID 12022872 DOI: 10.1021/Bi015982E  0.359
2002 Yegneswaran S, Fernández JA, Griffin JH, Dawson PE. Factor Va increases the affinity of factor Xa for prothrombin: A binding study using a novel photoactivable thiol-specific fluorescent probe Chemistry and Biology. 9: 485-494. PMID 11983337 DOI: 10.1016/S1074-5521(02)00132-1  0.307
2002 Offer J, Boddy CN, Dawson PE. Extending synthetic access to proteins with a removable acyl transfer auxiliary. Journal of the American Chemical Society. 124: 4642-6. PMID 11971712 DOI: 10.1021/Ja016731W  0.486
2002 Brik A, D'Souza LJ, Keinan E, Grynszpan F, Dawson PE. Cover Picture: ChemBioChem 9/2002 Chembiochem. 3: 799-799. DOI: 10.1002/1439-7633(20020902)3:9<799::Aid-Cbic799>3.0.Co;2-7  0.317
2001 Yan LZ, Dawson PE. Design and Synthesis of a Protein Catenane This work was supported by The Skaggs Institute for Chemical Biology, The Sloan Foundation, and NIH-GM570132 (PED). We thank Dr. Songpong Deechongkit for assistance with the analytical ultracentrifuge and CD measurements. Angewandte Chemie (International Ed. in English). 40: 3625-3627. PMID 11592201 DOI: 10.1002/1521-3773(20011001)40:19<3625::Aid-Anie3625>3.0.Co;2-Q  0.304
2001 Marinzi C, Bark SJ, Offer J, Dawson PE. A new scaffold for amide ligation Bioorganic and Medicinal Chemistry. 9: 2323-2328. PMID 11553471 DOI: 10.1016/S0968-0896(01)00136-5  0.385
2001 Yan LZ, Dawson PE. Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization. Journal of the American Chemical Society. 123: 526-33. PMID 11456564 DOI: 10.1021/Ja003265M  0.504
2001 Yan LZ, Dawson PE. Design and Synthesis of a Protein Catenane Angewandte Chemie. 113: 3737-3739. DOI: 10.1002/1521-3757(20011001)113:19<3737::Aid-Ange3737>3.0.Co;2-W  0.342
2000 Hackeng TM, Fernández JA, Dawson PE, Kent SB, Griffin JH. Chemical synthesis and spontaneous folding of a multidomain protein: anticoagulant microprotein S. Proceedings of the National Academy of Sciences of the United States of America. 97: 14074-8. PMID 11106381 DOI: 10.1073/Pnas.260239797  0.585
2000 Pelletier AJ, van der Laan LJ, Hildbrand P, Siani MA, Thompson DA, Dawson PE, Torbett BE, Salomon DR. Presentation of chemokine SDF-1 alpha by fibronectin mediates directed migration of T cells. Blood. 96: 2682-90. PMID 11023498  0.447
2000 Dawson PE, Kent SB. Synthesis of native proteins by chemical ligation. Annual Review of Biochemistry. 69: 923-60. PMID 10966479 DOI: 10.1146/Annurev.Biochem.69.1.923  0.619
2000 Beck ZQ, Hervio L, Dawson PE, Elder JH, Madison EL. Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development. Virology. 274: 391-401. PMID 10964781 DOI: 10.1006/Viro.2000.0420  0.379
2000 Brik A, Keinan E, Dawson PE. Protein synthesis by solid-phase chemical ligation using a safety catch linker Journal of Organic Chemistry. 65: 3829-3835. PMID 10864771 DOI: 10.1021/Jo000346S  0.465
2000 Offer J, Dawson PE. Nα-mercaptobenzylamine-assisted chemical ligation Organic Letters. 2: 23-26. PMID 10814236 DOI: 10.1021/Ol991184T  0.43
2000 Deniz AA, Laurence TA, Beligere GS, Dahan M, Martin AB, Chemla DS, Dawson PE, Schultz PG, Weiss S. Single-molecule protein folding: diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2. Proceedings of the National Academy of Sciences of the United States of America. 97: 5179-84. PMID 10792044 DOI: 10.1073/Pnas.090104997  0.386
2000 Marx PF, Hackeng TM, Dawson PE, Griffin JH, Meijers JCM, Bouma BN. Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage Journal of Biological Chemistry. 275: 12410-12415. PMID 10777524 DOI: 10.1074/Jbc.275.17.12410  0.313
2000 Cho S, Dawson PE, Dawson G. In vitro depalmitoylation of neurospecific peptides: Implication for infantile neuronal ceroid lipofuscinosis Journal of Neuroscience Research. 59: 32-38. PMID 10658183 DOI: 10.1002/(Sici)1097-4547(20000101)59:1<32::Aid-Jnr5>3.0.Co;2-A  0.457
2000 Pelletier AJ, Laan LJWvd, Hildbrand P, Siani MA, Thompson DA, Dawson PE, Torbett BE, Salomon DR. Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells Blood. 96: 2682-2690. DOI: 10.1182/Blood.V96.8.2682.H8002682_2682_2690  0.505
2000 Beligere GS, Dawson PE. Design, synthesis, and characterization of 4-ester CI2, a model for backbone hydrogen bonding in protein α-helices Journal of the American Chemical Society. 122: 12079-12082. DOI: 10.1021/Ja001648E  0.403
2000 Dawson PE, Beligere G, Yan L. Modification of the polypeptide backbone using chemical synthesis Journal of Molecular Graphics and Modelling. 18: 550. DOI: 10.1016/S1093-3263(00)80112-6  0.363
1999 Beligere GS, Dawson PE. Synthesis of a three zinc finger protein, Zif268, by native chemical ligation Biopolymers - Peptide Science Section. 51: 363-369. PMID 10685047 DOI: 10.1002/(Sici)1097-0282(1999)51:5<363::Aid-Bip6>3.0.Co;2-O  0.402
1999 Hackeng TM, Griffin JH, Dawson PE. Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology Proceedings of the National Academy of Sciences of the United States of America. 96: 10068-10073. PMID 10468563 DOI: 10.1073/Pnas.96.18.10068  0.51
1999 Coombs GS, Rao MS, Olson AJ, Dawson PE, Madison EL. Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains. The Journal of Biological Chemistry. 274: 24074-9. PMID 10446178 DOI: 10.1074/Jbc.274.34.24074  0.334
1999 Beligere GS, Dawson PE. Conformationally assisted protein ligation using C-terminal thioester peptides [14] Journal of the American Chemical Society. 121: 6332-6333. DOI: 10.1021/Ja9907919  0.456
1998 Hackeng TM, Dawson PE, Kent SB, Griffin JH. Chemical synthesis of human protein S thrombin-sensitive module and first epidermal growth factor module. Biopolymers. 46: 53-63. PMID 9664841 DOI: 10.1002/(Sici)1097-0282(199808)46:2<53::Aid-Bip1>3.0.Co;2-W  0.622
1997 Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins. Methods in Enzymology. 289: 545-64. PMID 9353737 DOI: 10.1016/S0076-6879(97)89063-5  0.758
1997 Muir TW, Dawson PE, Kent SB. Protein synthesis by chemical ligation of unprotected peptides in aqueous solution. Methods in Enzymology. 289: 266-98. PMID 9353726 DOI: 10.1016/S0076-6879(97)89052-0  0.72
1997 Dawson PE. Synthesis of chemokines by native chemical ligation. Methods in Enzymology. 287: 34-45. PMID 9330313 DOI: 10.1016/S0076-6879(97)87005-X  0.474
1997 Hackeng TM, Mounier CM, Bon C, Dawson PE, Griffin JH, Kent SB. Total chemical synthesis of enzymatically active human type II secretory phospholipase A2. Proceedings of the National Academy of Sciences of the United States of America. 94: 7845-50. PMID 9223275 DOI: 10.1073/Pnas.94.15.7845  0.603
1997 Dawson PE, Fitzgerald MC, Muir TW, Kent SBH. Methods for the chemical synthesis and readout of self-encoded arrays of polypeptide analogues Journal of the American Chemical Society. 119: 7917-7927. DOI: 10.1021/Ja963122T  0.699
1997 Dawson PE, Churchill MJ, Ghadiri MR, Kent SBH. Modulation of reactivity in native chemical ligation through the use of thiol additives Journal of the American Chemical Society. 119: 4325-4329. DOI: 10.1021/Ja962656R  0.417
1996 Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis. Chemistry & Biology. 3: 817-25. PMID 8939700 DOI: 10.1016/S1074-5521(96)90067-8  0.75
1996 Bruick RK, Dawson PE, Kent SB, Usman N, Joyce GF. Template-directed ligation of peptides to oligonucleotides. Chemistry & Biology. 3: 49-56. PMID 8807828 DOI: 10.1016/S1074-5521(96)90084-8  0.626
1994 Dawson PE, Muir TW, Clark-Lewis I, Kent SB. Synthesis of proteins by native chemical ligation. Science (New York, N.Y.). 266: 776-9. PMID 7973629  0.712
1993 Dawson PE, Kent SBH. Convenient total synthesis of a 4-helix template-assembled synthetic protein (TASP) molecule by chemoselective ligation Journal of the American Chemical Society. 115: 7263-7266. DOI: 10.1021/Ja00069A027  0.457
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