Year |
Citation |
Score |
2019 |
Leong WI, Ames RY, Haverkamp JM, Torres L, Kline J, Bans A, Rocha L, Gallotta M, Guiducci C, Coffman RL, Janatpour MJ. Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses. Oncotarget. 10: 7220-7237. PMID 31921384 DOI: 10.18632/Oncotarget.27322 |
0.39 |
|
2019 |
Kell SA, Kachura MA, Renn A, Traquina P, Coffman RL, Campbell JD. Preclinical development of the TLR9 agonist DV281 as an inhaled aerosolized immunotherapeutic for lung cancer: Pharmacological profile in mice, non-human primates, and human primary cells. International Immunopharmacology. 66: 296-308. PMID 30502651 DOI: 10.1016/J.Intimp.2018.11.019 |
0.436 |
|
2019 |
Degagné É, Romo J, Gallotta M, Kannan S, Coffman RL, Guiducci C. Abstract 2259: Tumor abscopal responses induced by the TLR9 agonist, SD-101, are strongly potentiated by a HDAC class I inhibitor, domatinostat Cancer Research. 79: 2259-2259. DOI: 10.1158/1538-7445.Am2019-2259 |
0.395 |
|
2018 |
Ribas A, Medina T, Kummar S, Amin A, Kalbasi A, Drabick JJ, Barve M, Daniels GA, Wong DJ, Schmidt EV, Candia AF, Coffman RL, Leung ACF, Janssen RS. SD-101 in Combination with Pembrolizumab in Advanced Melanoma: Results of a Phase 1b, Multicenter Study. Cancer Discovery. PMID 30154193 DOI: 10.1158/2159-8290.Cd-18-0280 |
0.355 |
|
2018 |
Frank MJ, Reagan PM, Bartlett NL, Gordon LI, Friedberg JW, Czerwinski DK, Long SR, Hoppe RT, Janssen RS, Candia AF, Coffman RL, Levy R. In Situ Vaccination with a TLR 9 Agonist and Local Low Dose Radiation Induces Systemic Responses in Untreated Indolent Lymphoma. Cancer Discovery. PMID 30154192 DOI: 10.1158/2159-8290.Cd-18-0743 |
0.375 |
|
2018 |
Gallotta M, Assi H, Degagné É, Kannan SK, Coffman RL, Guiducci C. Inhaled TLR9 Agonist Renders Lung Tumors Permissive to PD-1 Blockade by Promoting Optimal CD4+ and CD8+ T cell Interplay. Cancer Research. PMID 29945961 DOI: 10.1158/0008-5472.Can-18-0729 |
0.372 |
|
2017 |
Jackson S, Candia AF, Delaney S, Floettmann S, Wong C, Campbell JD, Kell S, Lum J, Hessel E, Traquina P, McHale M, Robinson I, Bell J, Fuhr R, Keeling D, ... Coffman RL, et al. First-in-human study with the inhaled TLR9 oligonucleotide agonist AZD1419 results in interferon responses in the lung, and is safe and well-tolerated. Clinical Pharmacology and Therapeutics. PMID 29134633 DOI: 10.1002/Cpt.938 |
0.643 |
|
2017 |
Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, et al. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. Jci Insight. 2. PMID 28931759 DOI: 10.1172/Jci.Insight.93397 |
0.371 |
|
2017 |
Candia A, Guiducci C, Coffman RL, Currie G, Leung A, Janssen R, Kummar S, Agarwala S, Nemunaitis J, Gonzalez R, Drabick J, Ribas A. Abstract LB-239: Pharmacodynamic changes confirm the mechanism of action mediating SD-101 efficacy, in combination with pembrolizumab, in a phase 1b/2 study in metastatic melanoma (MEL-01) Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-239 |
0.384 |
|
2017 |
Naik E, Ying C, Milley R, Calacsan C, Chipman S, Tüting T, Coffman R, Guiducci C. Abstract 5596: Intratumoral administration of a TLR9-adjuvanted nanoparticle cancer vaccine stimulates more effective immunity in both injected and un-injected tumor sites compared to subcutaneous administration Cancer Research. 77: 5596-5596. DOI: 10.1158/1538-7445.Am2017-5596 |
0.31 |
|
2017 |
Gallotta M, Assi H, Coffman RL, Guiducci C. Abstract 4696: Development of an inhaled TLR9 agonist for the immunotherapy of lung cancer Cancer Research. 77: 4696-4696. DOI: 10.1158/1538-7445.Am2017-4696 |
0.372 |
|
2016 |
Wang S, Campos J, Gallotta M, Gong M, Crain C, Naik E, Coffman RL, Guiducci C. Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799536 DOI: 10.1073/Pnas.1608555113 |
0.397 |
|
2016 |
Milley B, Kiwan R, Ott GS, Calacsan C, Kachura M, Campbell JD, Kanzler H, Coffman RL. Optimization, Production and Characterization of a CpG-Oligonucleotide-Ficoll Conjugate Nanoparticle Adjuvant for Enhanced Immunogenicity of Anthrax Protective Antigen. Bioconjugate Chemistry. PMID 27074387 DOI: 10.1021/Acs.Bioconjchem.6B00107 |
0.313 |
|
2016 |
Garcia-Martinez I, Santoro N, Chen Y, Hoque R, Ouyang X, Caprio S, Shlomchik MJ, Coffman RL, Candia A, Mehal WZ. Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9. The Journal of Clinical Investigation. PMID 26808498 DOI: 10.1172/Jci83885 |
0.3 |
|
2016 |
Levy R, Reagan PM, Friedberg JW, Bartlett NL, Gordon LI, Leung A, Peterkin J, Xing B, Coffman R, Janssen R, Candia A, Khodadoust M, Frank MJ, Long SR, Czerwinski DK, et al. SD-101, a Novel Class C CpG-Oligodeoxynucleotide (ODN) Toll-like Receptor 9 (TLR9) Agonist, Given with Low Dose Radiation for Untreated Low Grade B-Cell Lymphoma: Interim Results of a Phase 1/2 Trial Blood. 128: 2974-2974. DOI: 10.1182/Blood.V128.22.2974.2974 |
0.311 |
|
2016 |
Levy R, Bartlett N, Friedberg J, Reagan P, Gordon L, Bergman C, Coffman R, Janssen R, Candia A, Khodadoust M, Frank M, Long S, Czerwinski D, Chu M, Kohrt H. Abstract CT047: SD-101, a novel intratumoral class C CpG-ODN, given with low-dose radiation in patients with untreated low-grade B-cell lymphoma: interim results of a phase I trial Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ct047 |
0.329 |
|
2015 |
Kachura MA, Hickle C, Kell SA, Sathe A, Calacsan C, Kiwan R, Hall B, Milley R, Ott G, Coffman RL, Kanzler H, Campbell JD. A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-Immunization Protection against Inhaled Anthrax in Monkeys. Journal of Immunology (Baltimore, Md. : 1950). PMID 26608924 DOI: 10.4049/Jimmunol.1501903 |
0.381 |
|
2015 |
Jacquemin C, Schmitt N, Contin-Bordes C, Liu Y, Narayanan P, Seneschal J, Maurouard T, Dougall D, Davizon ES, Dumortier H, Douchet I, Raffray L, Richez C, Lazaro E, Duffau P, ... ... Coffman RL, et al. OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response. Immunity. 42: 1159-70. PMID 26070486 DOI: 10.1016/J.Immuni.2015.05.012 |
0.466 |
|
2015 |
Czerwinski DK, Long SR, Khodadoust M, Frank MJ, Chu MP, Okada A, McDonald KA, Kohrt HE, Bartlett NL, Reagan PM, Friedberg JW, Gordon LI, Coffman R, Janssen R, Levy R. Regulatory T Cells Are Depleted in Low-Grade Lymphoma By the Combination of Local Low-Dose Radiation Followed By Intratumoral CpG-ODN Blood. 126: 1539-1539. DOI: 10.1182/Blood.V126.23.1539.1539 |
0.417 |
|
2015 |
Seymour BW, Coffman RL. A Critical Role for IL4 in the Neonate after Exposure to Aerosolized Ovalbumin in a Murine Model of Allergen Sensitization Journal of Allergy and Clinical Immunology. 135: AB146. DOI: 10.1016/J.Jaci.2014.12.1415 |
0.513 |
|
2014 |
Campbell JD, Kell SA, Kozy HM, Lum JA, Sweetwood R, Chu M, Cunningham CR, Salamon H, Lloyd CM, Coffman RL, Hessel EM. A limited CpG-containing oligodeoxynucleotide therapy regimen induces sustained suppression of allergic airway inflammation in mice Thorax. 69: 565-573. PMID 24464743 DOI: 10.1136/Thoraxjnl-2013-204605 |
0.66 |
|
2013 |
Guiducci C, Gong M, Cepika AM, Xu Z, Tripodo C, Bennett L, Crain C, Quartier P, Cush JJ, Pascual V, Coffman RL, Barrat FJ. RNA recognition by human TLR8 can lead to autoimmune inflammation. The Journal of Experimental Medicine. 210: 2903-19. PMID 24277153 DOI: 10.1084/Jem.20131044 |
0.378 |
|
2011 |
Garcia-Romo GS, Caielli S, Vega B, Connolly J, Allantaz F, Xu Z, Punaro M, Baisch J, Guiducci C, Coffman RL, Barrat FJ, Banchereau J, Pascual V. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Science Translational Medicine. 3: 73ra20. PMID 21389264 DOI: 10.1126/Scitranslmed.3001201 |
0.372 |
|
2011 |
Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee LM, Coffman RL, Bachmann MF, DeFranco AL. Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity. 34: 375-84. PMID 21353603 DOI: 10.1016/J.Immuni.2011.01.011 |
0.4 |
|
2010 |
Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat FJ. Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9. The Journal of Experimental Medicine. 207: 2931-42. PMID 21115693 DOI: 10.1084/Jem.20101048 |
0.367 |
|
2010 |
Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M, Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz D, Glaichenhaus N, Julia V. CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung. Nature Medicine. 16: 1305-12. PMID 21037587 DOI: 10.1186/1479-5876-9-S2-P3 |
0.789 |
|
2010 |
Coffman RL, Sher A, Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity. 33: 492-503. PMID 21029960 DOI: 10.1016/J.Immuni.2010.10.002 |
0.318 |
|
2010 |
Guiducci C, Gong M, Xu Z, Gill M, Chaussabel D, Meeker T, Chan JH, Wright T, Punaro M, Bolland S, Soumelis V, Banchereau J, Coffman RL, Pascual V, Barrat FJ. TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. Nature. 465: 937-41. PMID 20559388 DOI: 10.1038/Nature09102 |
0.352 |
|
2010 |
Coffman RL. Immunology. The origin of TH2 responses. Science (New York, N.Y.). 328: 1116-7. PMID 20508120 DOI: 10.1126/Science.1192009 |
0.455 |
|
2010 |
Campbell JD, Buchmann P, Kesting S, Cunningham CR, Coffman RL, Hessel EM. Allergen-specific T cell responses to immunotherapy monitored by CD154 and intracellular cytokine expression. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 40: 1025-35. PMID 20412135 DOI: 10.1111/J.1365-2222.2010.03505.X |
0.706 |
|
2009 |
Campbell JD, Cho Y, Foster ML, Kanzler H, Kachura MA, Lum JA, Ratcliffe MJ, Sathe A, Leishman AJ, Bahl A, McHale M, Coffman RL, Hessel EM. CpG-containing immunostimulatory DNA sequences elicit TNF-α-dependent toxicity in rodents but not in humans Journal of Clinical Investigation. 119: 2564-2576. PMID 19726873 DOI: 10.1172/Jci38294 |
0.664 |
|
2009 |
Friedberg JW, Kelly JL, Neuberg D, Peterson DR, Kutok JL, Salloum R, Brenn T, Fisher DC, Ronan E, Dalton V, Rich L, Marquis D, Sims P, Rothberg PG, Liesveld J, ... ... Coffman R, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. British Journal of Haematology. 146: 282-91. PMID 19519691 DOI: 10.1111/J.1365-2141.2009.07773.X |
0.414 |
|
2009 |
Sims P, Coffman RL, Hessel EM. Biomarkers measuring the activity of Toll-like receptor ligands in clinical development programs. Methods in Molecular Biology (Clifton, N.J.). 517: 415-40. PMID 19378019 DOI: 10.1007/978-1-59745-541-1_25 |
0.659 |
|
2009 |
Guiducci C, Coffman RL, Barrat FJ. Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications. Journal of Internal Medicine. 265: 43-57. PMID 19093959 DOI: 10.1111/J.1365-2796.2008.02050.X |
0.378 |
|
2009 |
Campbell J, Buchmann P, Kesting S, King B, Coffman R, Hessel E. Successful Use of CD154 Expression and Intracellular Cytokine Staining to Monitor Changes in Allergen-Specific Th2 Cells in Peripheral Blood of Subjects in a Placebo-Controlled Study of Tolamba™, a Novel Immunotherapeutic Vaccine for Ragweed Allergies Journal of Allergy and Clinical Immunology. 123: S144-S144. DOI: 10.1016/J.Jaci.2008.12.539 |
0.662 |
|
2008 |
Mandl JN, Barry AP, Vanderford TH, Kozyr N, Chavan R, Klucking S, Barrat FJ, Coffman RL, Staprans SI, Feinberg MB. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nature Medicine. 14: 1077-87. PMID 18806803 DOI: 10.1038/Nm.1871 |
0.38 |
|
2008 |
Haining WN, Davies J, Kanzler H, Drury L, Brenn T, Evans J, Angelosanto J, Rivoli S, Russell K, George S, Sims P, Neuberg D, Li X, Kutok J, Morgan J, ... ... Coffman RL, et al. CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5626-34. PMID 18765557 DOI: 10.1158/1078-0432.Ccr-08-0526 |
0.405 |
|
2008 |
Barrat FJ, Coffman RL. Development of TLR inhibitors for the treatment of autoimmune diseases. Immunological Reviews. 223: 271-83. PMID 18613842 DOI: 10.1111/J.1600-065X.2008.00630.X |
0.338 |
|
2008 |
Guiducci C, Ghirelli C, Marloie-Provost MA, Matray T, Coffman RL, Liu YJ, Barrat FJ, Soumelis V. PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation. The Journal of Experimental Medicine. 205: 315-22. PMID 18227218 DOI: 10.1084/Jem.20070763 |
0.383 |
|
2007 |
Barrat FJ, Meeker T, Chan JH, Guiducci C, Coffman RL. Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms. European Journal of Immunology. 37: 3582-6. PMID 18034431 DOI: 10.1002/Eji.200737815 |
0.362 |
|
2007 |
Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nature Medicine. 13: 552-9. PMID 17479101 DOI: 10.1038/Nm1589 |
0.619 |
|
2007 |
Haining WN, Kanzler H, Davies J, Drury L, Kutok J, Brenn T, Angelosanto J, Evans J, Russell K, Rivoli S, George S, Morgan T, Li X, Coffman R, Wen P, et al. A Novel Role for CpG Oligonucleotides in Tumor Immunotherapy: CpG-ODN Induce Targeted Chemokine-Induced Lymphocyte Migration to the Peripheral Tissues in Humans. Blood. 110: 1791-1791. DOI: 10.1182/Blood.V110.11.1791.1791 |
0.444 |
|
2006 |
Yarovinsky F, Kanzler H, Hieny S, Coffman RL, Sher A. Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response. Immunity. 25: 655-64. PMID 17000122 DOI: 10.1016/J.Immuni.2006.07.015 |
0.394 |
|
2006 |
Guiducci C, Ott G, Chan JH, Damon E, Calacsan C, Matray T, Lee KD, Coffman RL, Barrat FJ. Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. The Journal of Experimental Medicine. 203: 1999-2008. PMID 16864658 DOI: 10.1084/Jem.20060401 |
0.363 |
|
2006 |
Gauvreau GM, Hessel EM, Boulet LP, Coffman RL, O'Byrne PM. Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses. American Journal of Respiratory and Critical Care Medicine. 174: 15-20. PMID 16574937 DOI: 10.1164/Rccm.200601-057Oc |
0.655 |
|
2006 |
Friedberg JW, Kelly J, Kutok JL, Salloum R, Fisher DC, Ronan E, Dalton V, Rich L, Marquis D, Rothberg PG, Liesveld J, Fisher RI, Coffman R, Mosmann T, Freedman AS. Combination Immunotherapy with a CpG Oligonucleotide and Rituximab (R) Augments the Immunological Response and Favorably Alters the Malignant Microenvironment of Follicular Lymphoma (FL). Blood. 108: 2713-2713. DOI: 10.1182/Blood.V108.11.2713.2713 |
0.372 |
|
2005 |
Hessel EM, Chu M, Lizcano JO, Chang B, Herman N, Kell SA, Wills-Karp M, Coffman RL. Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. The Journal of Experimental Medicine. 202: 1563-73. PMID 16314434 DOI: 10.1084/Jem.20050631 |
0.732 |
|
2005 |
Yang K, Puel A, Zhang S, Eidenschenk C, Ku CL, Casrouge A, Picard C, von Bernuth H, Senechal B, Plancoulaine S, Al-Hajjar S, Al-Ghonaium A, Maródi L, Davidson D, Speert D, ... ... Coffman RL, et al. Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity. 23: 465-78. PMID 16286015 DOI: 10.1016/J.Immuni.2005.09.016 |
0.337 |
|
2005 |
Barrat FJ, Meeker T, Gregorio J, Chan JH, Uematsu S, Akira S, Chang B, Duramad O, Coffman RL. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. The Journal of Experimental Medicine. 202: 1131-9. PMID 16230478 DOI: 10.1084/Jem.20050914 |
0.33 |
|
2005 |
Butcher EC, Rouse RV, Coffman RL, Nottenburg CN, Hardy RR, Weissman IL. Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. 1982. Journal of Immunology (Baltimore, Md. : 1950). 175: 1363-72. PMID 16034071 |
0.744 |
|
2005 |
Coffman RL, Hessel EM. Nonhuman primate models of asthma. The Journal of Experimental Medicine. 201: 1875-9. PMID 15967818 DOI: 10.1084/Jem.20050901 |
0.619 |
|
2005 |
Duramad O, Fearon KL, Chang B, Chan JH, Gregorio J, Coffman RL, Barrat FJ. Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 174: 5193-200. PMID 15843514 DOI: 10.4049/Jimmunol.174.9.5193 |
0.434 |
|
2005 |
Fahlén L, Read S, Gorelik L, Hurst SD, Coffman RL, Flavell RA, Powrie F. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. The Journal of Experimental Medicine. 201: 737-46. PMID 15753207 DOI: 10.1084/Jem.20040685 |
0.781 |
|
2005 |
Marshall JD, Fearon KL, Higgins D, Hessel EM, Kanzler H, Abbate C, Yee P, Gregorio J, Cruz TD, Lizcano JO, Zolotorev A, McClure HM, Brasky KM, Murthy KK, Coffman RL, et al. Superior activity of the type C class of ISS in vitro and in vivo across multiple species. Dna and Cell Biology. 24: 63-72. PMID 15699627 DOI: 10.1089/Dna.2005.24.63 |
0.656 |
|
2005 |
Friedberg JW, Kim H, McCauley M, Hessel EM, Sims P, Fisher DC, Nadler LM, Coffman RL, Freedman AS. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity. Blood. 105: 489-95. PMID 15358617 DOI: 10.1182/Blood-2004-06-2156 |
0.67 |
|
2005 |
Friedberg JW, Kelly J, Kutok JL, Salloum R, Brenn T, Fisher DC, Ronan E, McCauley M, Rich L, Marquis D, Rothberg PG, Liesveld J, Fisher RI, Coffman R, Mosmann T, et al. CpG Oligonucleotide (1018 ISS) May Overcome Rituximab (R) Resistance in Follicular Lymphoma (FL) through Enhanced ADCC, T Cell Expansion, and Alteration of Tumor Microenvironment. Blood. 106: 2434-2434. DOI: 10.1182/Blood.V106.11.2434.2434 |
0.415 |
|
2004 |
de Barros-Mazon S, Guariento ME, da Silva CA, Coffman RL, Abrahamsohn IA. Differential regulation of lymphoproliferative responses to Trypanosoma cruzi antigen in patients with the cardiac or indeterminate form of Chagas disease. Clinical Immunology (Orlando, Fla.). 111: 137-45. PMID 15093563 DOI: 10.1016/J.Clim.2004.01.002 |
0.399 |
|
2003 |
Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clinical & Developmental Immunology. 10: 35-42. PMID 14575156 DOI: 10.1080/10446670310001598483 |
0.362 |
|
2003 |
Duramad O, Fearon KL, Chan JH, Kanzler H, Marshall JD, Coffman RL, Barrat FJ. IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences. Blood. 102: 4487-92. PMID 12946990 DOI: 10.1182/Blood-2003-07-2465 |
0.477 |
|
2003 |
Marshall JD, Hessel EM, Gregorio J, Abbate C, Yee P, Chu M, Van Nest G, Coffman RL, Fearon KL. Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells. Nucleic Acids Research. 31: 5122-33. PMID 12930963 DOI: 10.1093/Nar/Gkg700 |
0.667 |
|
2003 |
Fearon K, Marshall JD, Abbate C, Subramanian S, Yee P, Gregorio J, Teshima G, Ott G, Tuck S, Van Nest G, Coffman RL. A minimal human immunostimulatory CpG motif that potently induces IFN-gamma and IFN-alpha production. European Journal of Immunology. 33: 2114-22. PMID 12884285 DOI: 10.1002/Eji.200323948 |
0.403 |
|
2003 |
Marshall JD, Fearon K, Abbate C, Subramanian S, Yee P, Gregorio J, Coffman RL, Van Nest G. Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions. Journal of Leukocyte Biology. 73: 781-92. PMID 12773511 DOI: 10.1189/Jlb.1202630 |
0.44 |
|
2003 |
Balabanian K, Couderc J, Bouchet-Delbos L, Amara A, Berrebi D, Foussat A, Baleux F, Portier A, Durand-Gasselin I, Coffman RL, Galanaud P, Peuchmaur M, Emilie D. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. Journal of Immunology (Baltimore, Md. : 1950). 170: 3392-400. PMID 12626600 DOI: 10.4049/Jimmunol.170.6.3392 |
0.443 |
|
2002 |
Feng CG, Kullberg MC, Jankovic D, Cheever AW, Caspar P, Coffman RL, Sher A. Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis. Infection and Immunity. 70: 6672-9. PMID 12438341 DOI: 10.1128/Iai.70.12.6672-6679.2002 |
0.471 |
|
2002 |
Murray HW, Lu CM, Mauze S, Freeman S, Moreira AL, Kaplan G, Coffman RL. Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infection and Immunity. 70: 6284-93. PMID 12379707 DOI: 10.1128/Iai.70.11.6284-6293.2002 |
0.42 |
|
2002 |
Seymour BW, Friebertshauser KE, Peake JL, Pinkerton KE, Coffman RL, Gershwin LJ. Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. Developmental Immunology. 9: 47-54. PMID 12353662 DOI: 10.1080/1044667021000003989 |
0.346 |
|
2002 |
Hurst SD, Muchamuel T, Gorman DM, Gilbert JM, Clifford T, Kwan S, Menon S, Seymour B, Jackson C, Kung TT, Brieland JK, Zurawski SM, Chapman RW, Zurawski G, Coffman RL. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. Journal of Immunology (Baltimore, Md. : 1950). 169: 443-53. PMID 12077275 DOI: 10.4049/Jimmunol.169.1.443 |
0.743 |
|
2002 |
Zou J, Young S, Zhu F, Gheyas F, Skeans S, Wan Y, Wang L, Ding W, Billah M, McClanahan T, Coffman RL, Egan R, Umland S. Microarray profile of differentially expressed genes in a monkey model of allergic asthma. Genome Biology. 3: research0020. PMID 12049661 DOI: 10.1186/Gb-2002-3-5-Research0020 |
0.359 |
|
2002 |
Kurata H, Lee HJ, McClanahan T, Coffman RL, O'Garra A, Arai N. Friend of GATA is expressed in naive Th cells and functions as a repressor of GATA-3-mediated Th2 cell development. Journal of Immunology (Baltimore, Md. : 1950). 168: 4538-45. PMID 11971000 DOI: 10.4049/Jimmunol.168.9.4538 |
0.489 |
|
2002 |
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. The Journal of Experimental Medicine. 195: 603-16. PMID 11877483 DOI: 10.1084/Jem.20011629 |
0.77 |
|
2002 |
Julia V, Hessel EM, Malherbe L, Glaichenhaus N, O'Garra A, Coffman RL. A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. Immunity. 16: 271-83. PMID 11869687 DOI: 10.1016/S1074-7613(02)00276-5 |
0.791 |
|
2001 |
Hurst SD, Seymour BW, Muchamuel T, Kurup VP, Coffman RL. Modulation of inhaled antigen-induced IgE tolerance by ongoing Th2 responses in the lung. Journal of Immunology (Baltimore, Md. : 1950). 166: 4922-30. PMID 11290770 DOI: 10.4049/Jimmunol.166.8.4922 |
0.378 |
|
2001 |
Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annual Review of Immunology. 19: 683-765. PMID 11244051 DOI: 10.1146/annurev.immunol.19.1.683 |
0.41 |
|
2001 |
Cua DJ, Hutchins B, LaFace DM, Stohlman SA, Coffman RL. Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 166: 602-8. PMID 11123343 DOI: 10.4049/Jimmunol.166.1.602 |
0.398 |
|
2001 |
Pardo A, Smith KM, Abrams J, Coffman R, Bustos M, McClanahan TK, Grein J, Murphy EE, Zlotnik A, Selman M. CCL18/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis. Journal of Leukocyte Biology. 70: 610-616. DOI: 10.1189/Jlb.70.4.610 |
0.342 |
|
2000 |
Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. Journal of Immunology (Baltimore, Md. : 1950). 165: 4848-53. PMID 11046008 DOI: 10.4049/Jimmunol.165.9.4848 |
0.533 |
|
2000 |
Tau GZ, von der Weid T, Lu B, Cowan S, Kvatyuk M, Pernis A, Cattoretti G, Braunstein NS, Coffman RL, Rothman PB. Interferon gamma signaling alters the function of T helper type 1 cells. The Journal of Experimental Medicine. 192: 977-86. PMID 11015439 DOI: 10.1084/Jem.192.7.977 |
0.506 |
|
2000 |
Abrahamsohn IA, da Silva AP, Coffman RL. Effects of interleukin-4 deprivation and treatment on resistance to Trypanosoma cruzi. Infection and Immunity. 68: 1975-9. PMID 10722591 DOI: 10.1128/Iai.68.4.1975-1979.2000 |
0.434 |
|
1999 |
Beebe AM, Cua DJ, Coffman RL. Genetic control of T helper subset differentiation in Leishmania major infection of mice. Microbes and Infection. 1: 89-94. PMID 10847771 DOI: 10.1016/S1286-4579(99)80019-7 |
0.331 |
|
1999 |
Fowell DJ, Shinkai K, Liao XC, Beebe AM, Coffman RL, Littman DR, Locksley RM. Impaired NFATc translocation and failure of Th2 development in Itk- deficient CD4+ T cells Immunity. 11: 399-409. PMID 10549622 DOI: 10.1016/S1074-7613(00)80115-6 |
0.503 |
|
1999 |
Rocha PN, Almeida RP, Bacellar O, de Jesus AR, Filho DC, Filho AC, Barral A, Coffman RL, Carvalho EM. Down-regulation of Th1 type of response in early human American cutaneous leishmaniasis. The Journal of Infectious Diseases. 180: 1731-4. PMID 10515843 DOI: 10.1086/315071 |
0.329 |
|
1999 |
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. The Journal of Experimental Medicine. 190: 995-1004. PMID 10510089 DOI: 10.1084/Jem.190.7.995 |
0.692 |
|
1999 |
Chatelain R, Mauze S, Varkila K, Coffman RL. Leishmania major infection in interleukin-4 and interferon-gamma depleted mice. Parasite Immunology. 21: 423-31. PMID 10417676 DOI: 10.1046/J.1365-3024.1999.00240.X |
0.44 |
|
1999 |
Coffman RL, Reiner SL. Instruction, selection, or tampering with the odds? Science. 284: 1283-1285. PMID 10383307 DOI: 10.1126/Science.284.5418.1283 |
0.404 |
|
1999 |
Chatelain R, Mauze S, Coffman RL. Experimental Leishmania major infection in mice: role of IL-10. Parasite Immunology. 21: 211-8. PMID 10320618 DOI: 10.1046/J.1365-3024.1999.00224.X |
0.431 |
|
1999 |
Cua DJ, Groux H, Hinton DR, Stohlman SA, Coffman RL. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 189: 1005-10. PMID 10075984 DOI: 10.1084/Jem.189.6.1005 |
0.645 |
|
1999 |
Doherty TM, Coffman RL. Ability of macrophage subsets to transfer resistance to murine leishmaniasis is dependent on IL-12 production. European Journal of Immunology. 29: 522-9. PMID 10064067 DOI: 10.1002/(Sici)1521-4141(199902)29:02<522::Aid-Immu522>3.0.Co;2-U |
0.567 |
|
1999 |
Groux H, Cottrez F, Rouleau M, Mauze S, Antonenko S, Hurst S, McNeil T, Bigler M, Roncarolo MG, Coffman RL. A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells. Journal of Immunology (Baltimore, Md. : 1950). 162: 1723-9. PMID 9973435 |
0.419 |
|
1998 |
Coffman RL, Beebe AM. Genetic control of the T cell response to Leishmania major infection. Advances in Experimental Medicine and Biology. 452: 61-6. PMID 9889960 DOI: 10.1007/978-1-4615-5355-7_8 |
0.484 |
|
1998 |
Read S, Mauze S, Asseman C, Bean A, Coffman R, Powrie F. CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. European Journal of Immunology. 28: 3435-3447. PMID 9842886 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3435::Aid-Immu3435>3.0.Co;2-P |
0.644 |
|
1998 |
Corrêa-Oliveira R, Malaquias LC, Falcão PL, Viana IR, Bahia-Oliveira LM, Silveira AM, Fraga LA, Prata A, Coffman RL, Lambertucci JR, Cunha-Melo JR, Martins-Filho OA, Wilson RA, Gazzinelli G. Cytokines as determinants of resistance and pathology in human Schistosoma mansoni infection. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 31: 171-7. PMID 9686196 DOI: 10.1590/S0100-879X1998000100024 |
0.551 |
|
1998 |
Bahia-Oliveira LM, Gomes JA, Rocha MO, Moreira MC, Lemos EM, Luz ZM, Pereira ME, Coffman RL, Dias JC, Cançado JR, Gazzinelli G, Corrêa-Oliveira R. IFN-gamma in human Chagas' disease: protection or pathology? Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 31: 127-31. PMID 9686189 DOI: 10.1590/S0100-879X1998000100017 |
0.496 |
|
1998 |
Terres G, Coffman RL. The role of IL-4 and IL-10 cytokines in controlling an anti-tumor response in vivo. International Immunology. 10: 823-32. PMID 9678764 DOI: 10.1093/Intimm/10.6.823 |
0.42 |
|
1998 |
Lu B, Ebensperger C, Dembic Z, Wang Y, Kvatyuk M, Lu T, Coffman RL, Pestka S, Rothman PB. Targeted disruption of the interferon-γ/receptor 2 gene results in severe immune defects in mice Proceedings of the National Academy of Sciences of the United States of America. 95: 8233-8238. PMID 9653170 DOI: 10.1073/Pnas.95.14.8233 |
0.344 |
|
1998 |
Powrie F, Mauze S, Coffman RL. CD4+ T-cells in the regulation of inflammatory responses in the intestine. Research in Immunology. 148: 576-81. PMID 9588837 DOI: 10.1016/S0923-2494(98)80152-1 |
0.568 |
|
1998 |
Ferlin WG, von der Weid T, Cottrez F, Ferrick DA, Coffman RL, Howard MC. The induction of a protective response in Leishmania major-infected BALB/c mice with anti-CD40 mAb. European Journal of Immunology. 28: 525-31. PMID 9521062 DOI: 10.1002/(Sici)1521-4141(199802)28:02<525::Aid-Immu525>3.0.Co;2-M |
0.453 |
|
1998 |
Seymour BW, Gershwin LJ, Coffman RL. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization. The Journal of Experimental Medicine. 187: 721-31. PMID 9480982 DOI: 10.1084/Jem.187.5.721 |
0.401 |
|
1998 |
Chatelain R, Coffman RL. Experimental leishmania major infection in mice: The role of IL-10 Journal of Dermatological Science. 16: S176. DOI: 10.1016/S0923-1811(98)84049-8 |
0.359 |
|
1998 |
Grünig G, Corry DB, Coffman RL, Rennick DM, Kurup VP. Animal Models Of Allergic Bronchopulmonary Aspergillosis Immunology and Allergy Clinics of North America. 18: 661-679. DOI: 10.1016/S0889-8561(05)70028-X |
0.491 |
|
1997 |
Malaquias LC, Falcão PL, Silveira AM, Gazzinelli G, Prata A, Coffman RL, Pizziolo V, Souza CP, Colley DG, Correa-Oliveira R. Cytokine regulation of human immune response to Schistosoma mansoni: analysis of the role of IL-4, IL-5 and IL-10 on peripheral blood mononuclear cell responses. Scandinavian Journal of Immunology. 46: 393-8. PMID 9350291 |
0.305 |
|
1997 |
Groux H, Sornasse T, Cottrez F, de Vries JE, Coffman RL, Roncarolo MG, Yssel H. Induction of human T helper cell type 1 differentiation results in loss of IFN-gamma receptor beta-chain expression. Journal of Immunology (Baltimore, Md. : 1950). 158: 5627-31. PMID 9190910 |
0.351 |
|
1997 |
Murray HW, Hariprashad J, Coffman RL. Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (Th2)-associated response model. The Journal of Experimental Medicine. 185: 867-74. PMID 9120392 DOI: 10.1084/Jem.185.5.867 |
0.465 |
|
1997 |
Doherty TM, Giese N, Morse HC, Coffman RL. Modulation of murine AIDS-related pathology by concurrent antibody treatment and coinfection with Leishmania major. Journal of Virology. 71: 3702-9. PMID 9094644 DOI: 10.1128/JVI.71.5.3702-3709.1997 |
0.569 |
|
1997 |
Coffman RL, von der Weid T. Multiple pathways for the initiation of T helper 2 (Th2) responses. The Journal of Experimental Medicine. 185: 373-5. PMID 9053437 DOI: 10.1084/Jem.185.3.373 |
0.492 |
|
1997 |
Mocci S, Coffman RL. The mechanism of in vitro T helper cell type 1 to T helper cell type 2 switching in highly polarized Leishmania major-specific T cell populations. Journal of Immunology (Baltimore, Md. : 1950). 158: 1559-64. PMID 9029090 |
0.41 |
|
1997 |
Dutra WO, Gollob KJ, Pinto-Dias JC, Gazzinelli G, Correa-Oliveira R, Coffman RL, Carvalho-Parra JF. Cytokine mRNA profile of peripheral blood mononuclear cells isolated from individuals with Trypanosoma cruzi chronic infection. Scandinavian Journal of Immunology. 45: 74-80. PMID 9010503 DOI: 10.1046/J.1365-3083.1997.D01-362.X |
0.771 |
|
1996 |
Ferlin WG, Severinson E, Ström L, Heath AW, Coffman RL, Ferrick DA, Howard MC. CD40 signaling induces interleukin-4-independent IgE switching in vivo. European Journal of Immunology. 26: 2911-5. PMID 8977285 DOI: 10.1002/eji.1830261216 |
0.398 |
|
1996 |
Abrahamsohn IA, Coffman RL. Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection. Experimental Parasitology. 84: 231-44. PMID 8932773 DOI: 10.1006/Expr.1996.0109 |
0.472 |
|
1996 |
Doherty TM, Coffman RL. Leishmania major: effect of infectious dose on T cell subset development in BALB/c mice. Experimental Parasitology. 84: 124-35. PMID 8932762 DOI: 10.1006/expr.1996.0098 |
0.48 |
|
1996 |
Morawetz RA, Gabriele L, Rizzo LV, Noben-Trauth N, Kühn R, Rajewsky K, Müller W, Doherty TM, Finkelman F, Coffman RL, Morse HC. Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse. The Journal of Experimental Medicine. 184: 1651-61. PMID 8920855 DOI: 10.1084/Jem.184.5.1651 |
0.505 |
|
1996 |
von der Weid T, Beebe AM, Roopenian DC, Coffman RL. Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class I-independent CD4+NK1.1- T cell population. Journal of Immunology (Baltimore, Md. : 1950). 157: 4421-7. PMID 8906817 |
0.367 |
|
1996 |
Clerici M, Sarin A, Berzofsky JA, Landay AL, Kessler HA, Hashemi F, Hendrix CW, Blatt SP, Rusnak J, Dolan MJ, Coffman RL, Henkart PA, Shearer GM. Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin. Aids (London, England). 10: 603-11. PMID 8780814 DOI: 10.1097/00002030-199606000-00005 |
0.4 |
|
1996 |
Gollob KJ, Dutra WO, Coffman RL. Early message expression of interleukin-4 and interferon-gamma, but not of interleukin-2 and interleukin-10, reflects later polarization of primary CD4+ T cell cultures. European Journal of Immunology. 26: 1565-70. PMID 8766562 DOI: 10.1002/Eji.1830260724 |
0.752 |
|
1996 |
Powrie F, Carlino J, Leach MW, Mauze S, Coffman RL. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. The Journal of Experimental Medicine. 183: 2669-74. PMID 8676088 DOI: 10.1084/Jem.183.6.2669 |
0.65 |
|
1996 |
Bacellar O, Brodskyn C, Guerreiro J, Barral-Netto M, Costa CH, Coffman RL, Johnson WD, Carvalho EM. Interleukin-12 restores interferon-gamma production and cytotoxic responses in visceral leishmaniasis. The Journal of Infectious Diseases. 173: 1515-8. PMID 8648233 DOI: 10.1093/Infdis/173.6.1515 |
0.379 |
|
1996 |
MURALI P, GUO J, XIA J, COFFMAN R, KURUP V. 456 Depletion of neutrophils promotes T helper 2 cytokine pathway in murine allergic aspergillosis Journal of Allergy and Clinical Immunology. 97: 296-296. DOI: 10.1016/S0091-6749(96)80674-9 |
0.414 |
|
1995 |
Coffman RL, Correa-Oliviera R, Mocci S. Reversal of polarized T helper 1 and T helper 2 cell populations in murine leishmaniasis. Ciba Foundation Symposium. 195: 20-5; discussion 25-. PMID 8724828 DOI: 10.1002/9780470514849.ch3 |
0.414 |
|
1995 |
Doherty TM, Morse HC, Coffman RL. Modulation of specific T cell responses by concurrent infection with Leishmania major and LP-BM5 murine leukemia viruses. International Immunology. 7: 131-8. PMID 7718509 DOI: 10.1093/intimm/7.1.131 |
0.562 |
|
1995 |
Mocci S, Coffman RL. Induction of a Th2 population from a polarized Leishmania-specific Th1 population by in vitro culture with IL-4. Journal of Immunology (Baltimore, Md. : 1950). 154: 3779-87. PMID 7706719 |
0.38 |
|
1995 |
Pernis A, Gupta S, Gollob KJ, Garfein E, Coffman RL, Schindler C, Rothman P. Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells. Science (New York, N.Y.). 269: 245-7. PMID 7618088 DOI: 10.1126/Science.7618088 |
0.657 |
|
1995 |
Tonnetti L, Spaccapelo R, Cenci E, Mencacci A, Puccetti P, Coffman RL, Bistoni F, Romani L. Interleukin-4 and -10 exacerbate candidiasis in mice. European Journal of Immunology. 25: 1559-65. PMID 7614983 DOI: 10.1002/EJI.1830250614 |
0.331 |
|
1994 |
Savelkoul HF, van Ommen R, Vossen AC, Breedland EG, Coffman RL, van Oudenaren A. Modulation of systemic cytokine levels by implantation of alginate encapsulated cells. Journal of Immunological Methods. 170: 185-96. PMID 8157997 DOI: 10.1016/0022-1759(94)90394-8 |
0.348 |
|
1994 |
Clerici M, Wynn TA, Berzofsky JA, Blatt SP, Hendrix CW, Sher A, Coffman RL, Shearer GM. Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus Journal of Clinical Investigation. 93: 768-775. PMID 8113410 DOI: 10.1172/Jci117031 |
0.305 |
|
1994 |
Kurup VP, Seymour BW, Choi H, Coffman RL. Particulate Aspergillus fumigatus antigens elicit a TH2 response in BALB/c mice. The Journal of Allergy and Clinical Immunology. 93: 1013-20. PMID 8006306 DOI: 10.1016/S0091-6749(94)70050-8 |
0.38 |
|
1994 |
Clerici M, Sarin A, Coffman RL, Wynn TA, Blatt SP, Hendrix CW, Wolf SF, Shearer GM, Henkart PA. Type 1/type 2 cytokine modulation of T-cell programed cell death as a model for human immunodeficiency virus pathogenesis Proceedings of the National Academy of Sciences of the United States of America. 91: 11811-11815. PMID 7991540 DOI: 10.1073/Pnas.91.25.11811 |
0.366 |
|
1994 |
Kurup VP, Choi H, Murali PS, Coffman RL. IgE and eosinophil regulation in a murine model of allergic aspergillosis. Journal of Leukocyte Biology. 56: 593-8. PMID 7964167 DOI: 10.1002/Jlb.56.5.593 |
0.448 |
|
1994 |
Powrie F, Correa-Oliveira R, Mauze S, Coffman RL. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. The Journal of Experimental Medicine. 179: 589-600. PMID 7905019 DOI: 10.1084/Jem.179.2.589 |
0.748 |
|
1994 |
Powrie F, Coffman RL, Correa-Oliveira R. Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. Research in Immunology. 145: 347-53. PMID 7701113 DOI: 10.1016/S0923-2494(94)80198-3 |
0.704 |
|
1994 |
Powrie F, Leach MW, Mauze S, Menon S, Caddle LB, Coffman RL. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity. 1: 553-62. PMID 7600284 DOI: 10.1016/1074-7613(94)90045-0 |
0.657 |
|
1994 |
Gollob KJ, Coffman RL. A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL-4-secreting cells. Journal of Immunology (Baltimore, Md. : 1950). 152: 5180-8. PMID 7514629 |
0.4 |
|
1993 |
Doherty TM, Coffman RL. Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 150: 5476-83. PMID 8515072 |
0.492 |
|
1993 |
Varkila K, Chatelain R, Leal LM, Coffman RL. Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection. European Journal of Immunology. 23: 262-8. PMID 8419179 DOI: 10.1002/Eji.1830230141 |
0.491 |
|
1993 |
Hostetler JS, Brummer E, Coffman RL, Stevens DA. Effect of anti-IL-4, interferon-gamma and an antifungal triazole (SCH 42427) in paracoccidioidomycosis: correlation of IgE levels with outcome. Clinical and Experimental Immunology. 94: 11-6. PMID 8403491 DOI: 10.1111/j.1365-2249.1993.tb05969.x |
0.301 |
|
1993 |
Coffman RL, Lebman DA, Rothman P. Mechanism and regulation of immunoglobulin isotype switching Advances in Immunology. 54: 229-270. PMID 8379463 DOI: 10.1016/S0065-2776(08)60536-2 |
0.358 |
|
1993 |
Nagelkerken L, Gollob KJ, Tielemans M, Coffman RL. Role of transforming growth factor-beta in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B. European Journal of Immunology. 23: 2306-10. PMID 8370407 DOI: 10.1002/EJI.1830230938 |
0.651 |
|
1993 |
Powrie F, Menon S, Coffman RL. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. European Journal of Immunology. 23: 2223-9. PMID 8370402 DOI: 10.1002/Eji.1830230926 |
0.605 |
|
1993 |
Powrie F, Menon S, Coffman RL. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. European Journal of Immunology. 23: 3043-9. PMID 8223881 DOI: 10.1002/eji.1830231147 |
0.347 |
|
1993 |
Powrie F, Coffman RL. Cytokine regulation of T-cell function: potential for therapeutic intervention. Trends in Pharmacological Sciences. 14: 164-8. PMID 8105593 DOI: 10.1016/0165-6147(93)90202-U |
0.684 |
|
1993 |
Gollob KJ, Nagelkerken L, Coffman RL. Endogenous retroviral superantigen presentation by B cells induces the development of type 1 CD4+ T helper lymphocytes. European Journal of Immunology. 23: 2565-71. PMID 8104796 DOI: 10.1002/eji.1830231028 |
0.662 |
|
1993 |
Powrie F, Coffman RL. Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunology Today. 14: 270-4. PMID 8104408 DOI: 10.1016/0167-5699(93)90044-L |
0.684 |
|
1993 |
Coffman RL. Mechanisms of helper T-cell regulation of B-cell activity. Annals of the New York Academy of Sciences. 681: 25-8. PMID 8102840 DOI: 10.1111/j.1749-6632.1993.tb22865.x |
0.302 |
|
1993 |
Powrie F, Coffman RL. Inhibition of cell-mediated immunity by IL4 and IL10. Research in Immunology. 144: 639-43. PMID 7905657 DOI: 10.1016/S0923-2494(05)80019-7 |
0.579 |
|
1993 |
Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. International Immunology. 5: 1461-71. PMID 7903159 DOI: 10.1093/Intimm/5.11.1461 |
0.62 |
|
1993 |
Doherty TM, Kastelein R, Menon S, Andrade S, Coffman RL. Modulation of murine macrophage function by IL-13. Journal of Immunology (Baltimore, Md. : 1950). 151: 7151-60. PMID 7903102 |
0.516 |
|
1992 |
Tepper RI, Coffman RL, Leder P. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science (New York, N.Y.). 257: 548-51. PMID 1636093 DOI: 10.1126/Science.1636093 |
0.403 |
|
1992 |
Sher A, Coffman RL. Regulation of immunity to parasites by T cells and T cell-derived cytokines Annual Review of Immunology. 10: 385-409. PMID 1590992 DOI: 10.1146/ANNUREV.IY.10.040192.002125 |
0.348 |
|
1992 |
Schultz CL, Rothman P, Kühn R, Kehry M, Müller W, Rajewsky K, Alt F, Coffman RL. T helper cell membranes promote IL-4-independent expression of germ-line C gamma 1 transcripts in B cells. Journal of Immunology (Baltimore, Md. : 1950). 149: 60-4. PMID 1535089 |
0.327 |
|
1992 |
Chatelain R, Varkila K, Coffman RL. IL-4 induces a Th2 response in Leishmania major-infected mice. Journal of Immunology (Baltimore, Md. : 1950). 148: 1182-7. PMID 1531351 |
0.354 |
|
1991 |
Rothman P, Lutzker S, Gorham B, Stewart V, Coffman R, Alt FW. Structure and expression of germline immunoglobulin gamma 3 heavy chain gene transcripts: implications for mitogen and lymphokine directed class-switching. International Immunology. 2: 621-7. PMID 2126196 DOI: 10.1093/Intimm/2.7.621 |
0.4 |
|
1991 |
Coffman RL, Chatelain R, Leal LM, Varkila K. Leishmania major infection in mice: a model system for the study of CD4+ T-cell subset differentiation. Research in Immunology. 142: 36-40. PMID 1845161 DOI: 10.1016/0923-2494(91)90009-8 |
0.477 |
|
1991 |
Hodgkin PD, Yamashita LC, Seymour B, Coffman RL, Kehry MR. Membranes from both Th1 and Th2 T cell clones stimulate B cell proliferation and prepare B cells for lymphokine-induced differentiation to secrete Ig. Journal of Immunology (Baltimore, Md. : 1950). 147: 3696-702. PMID 1834744 |
0.359 |
|
1991 |
Coffman RL, Mosmann TR. CD4+ T-cell subsets: regulation of differentiation and function Research in Immunology. 142: 7-9. PMID 1829263 DOI: 10.1016/0923-2494(91)90002-Z |
0.344 |
|
1991 |
Savelkoul HF, Seymour BW, Sullivan L, Coffman RL. IL-4 can correct defective IgE production in SJA/9 mice. Journal of Immunology (Baltimore, Md. : 1950). 146: 1801-5. PMID 1826012 |
0.363 |
|
1991 |
Coffman RL, Varkila K, Scott P, Chatelain R. Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo. Immunological Reviews. 123: 189-207. PMID 1684779 DOI: 10.1111/J.1600-065X.1991.Tb00611.X |
0.44 |
|
1991 |
KURUP V, SEYMOUR B, CHOI H, COFFMAN R. 9 Irrelevant pre-existing IgE enhances antigen specific secondary responses in mice Journal of Allergy and Clinical Immunology. 87: 141. DOI: 10.1016/0091-6749(91)91292-2 |
0.345 |
|
1990 |
Scott P, Pearce E, Cheever AW, Coffman RL, Sher A. Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunological Reviews. 112: 161-82. PMID 2575073 DOI: 10.1111/J.1600-065X.1989.Tb00557.X |
0.505 |
|
1990 |
Hodgkin PD, Yamashita LC, Coffman RL, Kehry MR. Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines. Journal of Immunology (Baltimore, Md. : 1950). 145: 2025-34. PMID 2144543 |
0.343 |
|
1990 |
Taguchi T, McGhee JR, Coffman RL, Beagley KW, Eldridge JH, Takatsu K, Kiyono H. Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay. Journal of Immunological Methods. 128: 65-73. PMID 2139082 DOI: 10.1016/0022-1759(90)90464-7 |
0.401 |
|
1990 |
Sher A, Coffman RL, Hieny S, Scott P, Cheever AW. Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proceedings of the National Academy of Sciences of the United States of America. 87: 61-5. PMID 2104985 DOI: 10.1073/Pnas.87.1.61 |
0.326 |
|
1990 |
Gauchat JF, Lebman DA, Coffman RL, Gascan H, De Vries JE. Structure and expression of germline ε transcripts in human B cells induced by interleukin 4 to switch to IgE production Journal of Experimental Medicine. 172: 463-473. PMID 1695667 DOI: 10.1084/Jem.172.2.463 |
0.356 |
|
1990 |
Finkelman FD, Holmes J, Katona IM, Urban JF, Beckmann MP, Park LS, Schooley KA, Coffman RL, Mosmann TR, Paul WE. Lymphokine control of in vivo immunoglobulin isotype selection. Annual Review of Immunology. 8: 303-33. PMID 1693082 DOI: 10.1146/annurev.iy.08.040190.001511 |
0.359 |
|
1989 |
Coffman RL, Lebman DA, Shrader B. Transforming growth factor β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes Journal of Experimental Medicine. 170: 1039-1044. PMID 2788703 DOI: 10.1084/Jem.170.3.1039 |
0.335 |
|
1989 |
Coffman RL, Seymour BW, Hudak S, Jackson J, Rennick D. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science (New York, N.Y.). 245: 308-10. PMID 2787531 DOI: 10.1126/Science.2787531 |
0.431 |
|
1989 |
Mosmann TR, Coffman RL. Heterogeneity of cytokine secretion patterns and functions of helper T cells Advances in Immunology. 46: 111-147. PMID 2528896 DOI: 10.1016/S0065-2776(08)60652-5 |
0.513 |
|
1989 |
Coffman RL. T-helper heterogeneity and immune response patterns. Hospital Practice (Office Ed.). 24: 101-5, 108, 113-14, . PMID 2527860 DOI: 10.1080/21548331.1989.11703766 |
0.391 |
|
1989 |
Heinzel FP, Sadick MD, Holaday BJ, Coffman RL, Locksley RM. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. The Journal of Experimental Medicine. 169: 59-72. PMID 2521244 DOI: 10.1084/Jem.169.1.59 |
0.327 |
|
1988 |
Chiu CP, Moulds C, Coffman RL, Rennick D, Lee F. Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells Proceedings of the National Academy of Sciences of the United States of America. 85: 7099-7103. PMID 3262872 DOI: 10.1073/Pnas.85.19.7099 |
0.412 |
|
1988 |
Lebman DA, Coffman RL. The effects of IL-4 and IL-5 on the IgA response by murine Peyer's patch B cell subpopulations Journal of Immunology. 141: 2050-2056. PMID 3262648 |
0.337 |
|
1988 |
Savelkoul HF, Termeulen J, Coffman RL, Van der Linde-Preesman RA. Frequency analysis of functional Ig C epsilon gene expression in the presence and absence of interleukin 4 in lipopolysaccharide-reactive murine B cells from high and low IgE responder strains. European Journal of Immunology. 18: 1209-15. PMID 3262065 DOI: 10.1002/EJI.1830180810 |
0.373 |
|
1988 |
Herron LR, Coffman RL, Kotzin BL. Enhanced response of autoantibody-secreting B cells from young NZB/NZW mice to T-cell-derived differentiation signals. Clinical Immunology and Immunopathology. 46: 314-27. PMID 3257428 DOI: 10.1016/0090-1229(88)90193-6 |
0.36 |
|
1988 |
Lebman DA, Coffman RL. Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures Journal of Experimental Medicine. 168: 853-862. PMID 3049907 |
0.348 |
|
1988 |
Hodgkin PD, Bond MW, O'Garra A, Frank G, Lee F, Coffman RL, Zlotnik A, Howard M. Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate. Journal of Immunology (Baltimore, Md. : 1950). 141: 151-7. PMID 2967865 |
0.321 |
|
1988 |
Coffman RL, Seymour BW, Lebman DA, Hiraki DD, Christiansen JA, Shrader B, Cherwinski HM, Savelkoul HF, Finkelman FD, Bond MW. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunological Reviews. 102: 5-28. PMID 2966762 DOI: 10.1111/J.1600-065X.1988.Tb00739.X |
0.426 |
|
1988 |
Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. The Journal of Experimental Medicine. 168: 1675-84. PMID 2903212 DOI: 10.1084/Jem.168.5.1675 |
0.384 |
|
1988 |
Sanders VM, Fernandez-Botran R, Coffman RL, Mosmann TR, Vitetta ES. A single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cell. Proceedings of the National Academy of Sciences of the United States of America. 85: 7724-8. PMID 2459715 DOI: 10.1073/Pnas.85.20.7724 |
0.461 |
|
1988 |
Stevens TL, Bossie A, Sanders VM, Fernandez-Botran R, Coffman RL, Mosmann TR, Vitetta ES. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature. 334: 255-8. PMID 2456466 DOI: 10.1038/334255A0 |
0.428 |
|
1987 |
Mosmann TR, Coffman RL. Two types of mouse helper T-cell clone Implications for immune regulation. Immunology Today. 8: 223-7. PMID 25290434 DOI: 10.1016/0167-5699(87)90171-X |
0.458 |
|
1987 |
Coffman RL, Shrader B, Carty J, Mosmann TR, Bond MW. A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization Journal of Immunology. 139: 3685-3690. PMID 2960739 |
0.343 |
|
1987 |
Mosmann TR, Coffman RL. Two types of mouse helper T-cell clone. Implications for immune regulation Immunology Today. 8: 223-227. DOI: 10.1016/0167-5699(87)90171-X |
0.352 |
|
1986 |
Mosmann TR, Bond MW, Coffman RL, Ohara J, Paul WE. T-cell and mast cell lines respond to B-cell stimulatory factor 1 Proceedings of the National Academy of Sciences of the United States of America. 83: 5654-5658. PMID 3090545 DOI: 10.1073/Pnas.83.15.5654 |
0.427 |
|
1983 |
Coffman RL. Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development. Immunological Reviews. 69: 5-23. PMID 6984001 DOI: 10.1111/J.1600-065X.1983.Tb00446.X |
0.366 |
|
1983 |
Joho R, Nottenburg C, Coffman RL, Weissman IL. Immunoglobulin gene rearrangement and expression during lymphocyte development. Current Topics in Developmental Biology. 18: 15-58. PMID 6404604 DOI: 10.1016/S0070-2153(08)60578-5 |
0.743 |
|
1983 |
Coffman RL, Weissman IL. Immunoglobulin gene rearrangement during pre-B cell differentiation. The Journal of Molecular and Cellular Immunology : Jmci. 1: 31-41. PMID 6336590 |
0.389 |
|
1983 |
Lepault F, Coffman RL, Weissman IL. Characteristics of thymus-homing bone marrow cells. Journal of Immunology (Baltimore, Md. : 1950). 131: 64-9. PMID 6134770 |
0.404 |
|
1982 |
Butcher EC, Reichert RA, Coffman RL, Nottenburg C, Weissman IL. Surface phenotype and migratory capability of Peyer's patch germinal center cells. Advances in Experimental Medicine and Biology. 149: 765-72. PMID 6983239 DOI: 10.1007/978-1-4684-9066-4_106 |
0.764 |
|
1982 |
Butcher EC, Rouse RV, Coffman RL, Nottenburg CN, Hardy RR, Weissman IL. Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 129: 2698-707. PMID 6982940 |
0.475 |
|
1981 |
Coffman RL, Weissman IL. B220: a B cell-specific member of th T200 glycoprotein family. Nature. 289: 681-3. PMID 6970340 DOI: 10.1038/289681a0 |
0.457 |
|
1981 |
Coffman RL, Weissman IL. A monoclonal antibody that recognizes B cells and B cell precursors in mice. The Journal of Experimental Medicine. 153: 269-79. PMID 6787164 DOI: 10.1084/jem.153.2.269 |
0.428 |
|
1979 |
Warnke RA, Slavin S, Coffman RL, Butcher EC, Knapp MR, Strober S, Weissman IL. The pathology and homing of a transplantable murine B cell leukemia (BCL1). Journal of Immunology (Baltimore, Md. : 1950). 123: 1181-8. PMID 381519 |
0.446 |
|
1977 |
Coffman RL, Cohn M. The class of surface immunoglobulin on virgin and memory B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 118: 1806-15. PMID 67148 |
0.507 |
|
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