Year |
Citation |
Score |
2022 |
Francis D, Farooque S, Meager A, Derks D, Leggott A, Warriner S, O'Neill AJ, Nelson A. Algorithm-driven activity-directed expansion of a series of antibacterial quinazolinones. Organic & Biomolecular Chemistry. PMID 36448404 DOI: 10.1039/d2ob01404a |
0.493 |
|
2020 |
Fey N, Green AI, Tinworth CP, Warriner S, Nelson A. Computational Mapping of Dirhodium(II) Catalysts. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32964545 DOI: 10.1002/chem.202003801 |
0.391 |
|
2020 |
Leggott A, Clarke JE, Chow S, Warriner SL, O'Neill AJ, Nelson A. Activity-directed expansion of a series of antibacterial agents. Chemical Communications (Cambridge, England). PMID 32538401 DOI: 10.1039/D0Cc02361B |
0.452 |
|
2020 |
Green A, Hobor F, Tinworth C, Warriner S, Wilson A, Nelson A. Activity-directed synthesis of inhibitors of the p53/hDM2 protein-protein interaction. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32458465 DOI: 10.1002/Chem.202002153 |
0.543 |
|
2020 |
Chow S, Green AI, Arter C, Liver S, Leggott A, Trask L, Karageorgis G, Warriner S, Nelson A. Efficient Approaches for the Synthesis of Diverse α-Diazo Amides Synthesis. 52: 1695-1706. DOI: 10.1055/S-0039-1690905 |
0.553 |
|
2020 |
Green AI, Hobor F, Tinworth CP, Warriner S, Wilson AJ, Nelson A. Cover Feature: Activity‐Directed Synthesis of Inhibitors of the p53/ h DM2 Protein–Protein Interaction (Chem. Eur. J. 47/2020) Chemistry: a European Journal. 26: 10645-10645. DOI: 10.1002/Chem.202003334 |
0.466 |
|
2019 |
Zhang R, McIntyre PJ, Collins PM, Foley DJ, Arter C, von Delft F, Bayliss R, Warriner S, Nelson A. Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31026091 DOI: 10.2210/Pdb6R49/Pdb |
0.489 |
|
2017 |
Dow M, Marchetti F, Abrahams K, Vaz L, Besra G, Warriner S, Nelson A. Modular Synthesis of Diverse Natural Product-like Macrocycles: Discovery of Hits with Antimycobacterial Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28374952 DOI: 10.1002/Chem.201701150 |
0.584 |
|
2017 |
Hunter J, Rice S, Lowe R, Pask CM, Warriner S, Sridharan V. Iridium catalyzed alkylation of 2′-hydroxyacetophenone with alcohols under thermal or microwave conditions Tetrahedron Letters. 58: 4400-4402. DOI: 10.1016/J.Tetlet.2017.10.024 |
0.331 |
|
2016 |
Hauser JR, Beard HA, Bayana ME, Jolley KE, Warriner SL, Bon RS. Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole. Beilstein Journal of Organic Chemistry. 12: 2019-2025. PMID 27829906 DOI: 10.3762/Bjoc.12.189 |
0.338 |
|
2016 |
Burslem GM, Kyle HF, Breeze AL, Edwards TA, Nelson A, Warriner SL, Wilson AJ. Towards "bionic" proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics. Chemical Communications (Cambridge, England). PMID 27009828 DOI: 10.1039/C6Cc01812B |
0.388 |
|
2016 |
Burslem GM, Kyle HF, Prabhakaran P, Breeze AL, Edwards TA, Warriner SL, Nelson A, Wilson AJ. Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups. Organic & Biomolecular Chemistry. PMID 27005701 DOI: 10.1039/C6Ob00078A |
0.494 |
|
2015 |
Karageorgis G, Dow M, Aimon A, Warriner S, Nelson A. Frontispiece: Activity-Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists. Angewandte Chemie (International Ed. in English). 54. PMID 26523750 DOI: 10.1002/anie.201584661 |
0.457 |
|
2015 |
Karageorgis G, Dow M, Aimon A, Warriner S, Nelson A. Activity-Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists. Angewandte Chemie (International Ed. in English). 54: 13538-44. PMID 26358926 DOI: 10.1002/Anie.201506944 |
0.579 |
|
2015 |
Kyle HF, Wickson KF, Stott J, Burslem GM, Breeze AL, Tiede C, Tomlinson DC, Warriner SL, Nelson A, Wilson AJ, Edwards TA. Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies. Molecular Biosystems. PMID 26135796 DOI: 10.1039/C5Mb00284B |
0.42 |
|
2015 |
Firth JD, Zhang R, Morgentin R, Guilleux R, Kalliokoski T, Warriner S, Foster R, Marsden SP, Nelson A. Exploitation of the Ugi–Joullié Reaction in the Synthesis of Libraries of Drug-Like Bicyclic Hydantoins Synthesis (Germany). DOI: 10.1055/S-0034-1378704 |
0.574 |
|
2014 |
Karageorgis G, Warriner S, Nelson A. Efficient discovery of bioactive scaffolds by activity-directed synthesis. Nature Chemistry. 6: 872-6. PMID 25242481 DOI: 10.1038/Nchem.2034 |
0.588 |
|
2014 |
Nelson A, Warriner S, Davey S. Parallels with nature. Nature Chemistry. 6: 845-6. PMID 25242468 DOI: 10.1038/Nchem.2076 |
0.502 |
|
2014 |
Burslem GM, Kyle HF, Breeze AL, Edwards TA, Nelson A, Warriner SL, Wilson AJ. Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction. Chembiochem : a European Journal of Chemical Biology. 15: 1083-7. PMID 24782431 DOI: 10.1002/Cbic.201400009 |
0.435 |
|
2014 |
James T, Maclellan P, Burslem GM, Simpson I, Grant JA, Warriner S, Sridharan V, Nelson A. A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds. Organic & Biomolecular Chemistry. 12: 2584-91. PMID 24614952 DOI: 10.1039/C3Ob42512F |
0.574 |
|
2014 |
Martin HL, Adams M, Higgins J, Bond J, Morrison EE, Bell SM, Warriner S, Nelson A, Tomlinson DC. High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers. Plos One. 9: e88338. PMID 24505478 DOI: 10.1371/Journal.Pone.0088338 |
0.483 |
|
2013 |
Maurya SK, Dow M, Warriner S, Nelson A. Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks. Beilstein Journal of Organic Chemistry. 9: 775-85. PMID 23766790 DOI: 10.3762/Bjoc.9.88 |
0.549 |
|
2012 |
Joce C, White R, Stockley PG, Warriner S, Turnbull WB, Nelson A. Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues. Bioorganic & Medicinal Chemistry Letters. 22: 278-84. PMID 22137339 DOI: 10.1016/J.Bmcl.2011.11.017 |
0.49 |
|
2011 |
Murrison S, Maurya SK, Einzinger C, McKeever-Abbas B, Warriner S, Nelson A. Synthesis of Skeletally Diverse Alkaloid‐Like Small Molecules European Journal of Organic Chemistry. 2011: 2354-2359. DOI: 10.1002/Ejoc.201100116 |
0.576 |
|
2009 |
Joce C, Caryl J, Stockley PG, Warriner S, Nelson A. Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA. Organic & Biomolecular Chemistry. 7: 635-8. PMID 19194573 DOI: 10.1039/B816495A |
0.46 |
|
2009 |
O'Leary-Steele C, Cordier C, Hayes J, Warriner S, Nelson A. A fluorous-tagged "safety catch" linker for preparing heterocycles by ring-closing metathesis. Organic Letters. 11: 915-8. PMID 19173645 DOI: 10.1021/Ol802848J |
0.544 |
|
2009 |
Murrison S, Glowacki D, Einzinger C, Titchmarsh J, Bartlett S, McKeever-Abbas B, Warriner S, Nelson A. Remarkably slow rotation about a single bond between an sp(3)-hybridised carbon atom and an aromatic ring without ortho substituents. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 2185-9. PMID 19156809 DOI: 10.1002/Chem.200802127 |
0.476 |
|
2009 |
Morton D, Leach S, Cordier C, Warriner S, Nelson A. Synthesis of natural-product-like molecules with over eighty distinct scaffolds. Angewandte Chemie (International Ed. in English). 48: 104-9. PMID 19016294 DOI: 10.1002/Anie.200804486 |
0.55 |
|
2008 |
Cordier C, Morton D, Leach S, Woodhall T, O'Leary-Steele C, Warriner S, Nelson A. An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis. Organic & Biomolecular Chemistry. 6: 1734-7. PMID 18452006 DOI: 10.1039/B804769N |
0.509 |
|
2008 |
Leach SG, Cordier CJ, Morton D, McKiernan GJ, Warriner S, Nelson A. A fluorous-tagged linker from which small molecules are released by ring-closing metathesis. The Journal of Organic Chemistry. 73: 2753-9. PMID 18327951 DOI: 10.1021/Jo7026273 |
0.55 |
|
2005 |
Bartlett S, Beddard GS, Jackson RM, Kayser V, Kilner C, Leach A, Nelson A, Oledzki PR, Parker P, Reid GD, Warriner SL. Comparison of the ATP binding sites of protein kinases using conformationally diverse bisindolylmaleimides. Journal of the American Chemical Society. 127: 11699-708. PMID 16104747 DOI: 10.1021/Ja050576U |
0.439 |
|
2004 |
Burt J, Dean T, Warriner S. The parallel synthesis of a disaccharide library using a solid phase, peptide-templated strategy. Chemical Communications (Cambridge, England). 454-5. PMID 14765255 DOI: 10.1039/B313571C |
0.311 |
|
2003 |
Bartlett S, Hodgson R, Holland JM, Jones M, Kilner C, Nelson A, Warriner S. Exploiting predisposition in the stereoselective synthesis of mono-, bi- and tetracyclic oxygen heterocycles: equilibration between, and trapping of, alternative di- and tetraacetals. Organic & Biomolecular Chemistry. 1: 2393-402. PMID 12945714 DOI: 10.1039/B303089J |
0.531 |
|
2000 |
Green S, Nelson A, Warriner S, Whittaker B. Synthesis and investigation of the configurational stability of some dimethylammonium borate salts Journal of the Chemical Society-Perkin Transactions 1. 4403-4408. DOI: 10.1039/B005954O |
0.448 |
|
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