Year |
Citation |
Score |
2018 |
Morris SM, Mhyre AJ, Carmack SS, Myers CH, Burns C, Ye W, Ferrer M, Olson JM, Klinghoffer RA. A modified gene trap approach for improved high-throughput cancer drug discovery. Oncogene. PMID 29717260 DOI: 10.1038/S41388-018-0274-4 |
0.317 |
|
2012 |
Berndt JD, Frazier J, Grenley M, Bahrami B, Moon RT, Olson J, Klinghoffer R. Abstract 5116: Identification and rapidin vivovalidation of a novel drug combination for treating melanoma Cancer Research. 72: 5116-5116. DOI: 10.1158/1538-7445.Am2012-5116 |
0.35 |
|
2010 |
Andersen JN, Sathyanarayanan S, Di Bacco A, Chi A, Zhang T, Chen AH, Dolinski B, Kraus M, Roberts B, Arthur W, Klinghoffer RA, Gargano D, Li L, Feldman I, Lynch B, et al. Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. Science Translational Medicine. 2: 43ra55. PMID 20686178 DOI: 10.1126/Scitranslmed.3001065 |
0.347 |
|
2003 |
Hamilton TG, Klinghoffer RA, Corrin PD, Soriano P. Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms Molecular and Cellular Biology. 23: 4013-4025. PMID 12748302 DOI: 10.1128/Mcb.23.11.4013-4025.2003 |
0.682 |
|
2002 |
Cary LA, Klinghoffer RA, Sachsenmaier C, Cooper JA. Src catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading Molecular and Cellular Biology. 22: 2427-2440. PMID 11909938 DOI: 10.1128/MCB.22.8.2427-2440.2002 |
0.452 |
|
2002 |
Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. An allelic series at the PDGFαR locus indicates unequal contributions of distinct signaling pathways during development Developmental Cell. 2: 103-113. PMID 11782318 DOI: 10.1016/S1534-5807(01)00103-4 |
0.647 |
|
2001 |
Klinghoffer RA, Mueting-Nelsen PF, Faerman A, Shani M, Soriano P. The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions Molecular Cell. 7: 343-354. PMID 11239463 DOI: 10.1016/S1097-2765(01)00182-4 |
0.643 |
|
2000 |
Tallquist MD, Klinghoffer RA, Heuchel R, Mueting-Nelsen PF, Corrin PD, Heldin CH, Johnson RJ, Soriano P. Retention of PDGFR-β function in mice in the absence of phosphatidylinositol 3′-kinase anti phospholipase Cγ signaling pathways Genes and Development. 14: 3179-3190. PMID 11124809 DOI: 10.1101/Gad.844700 |
0.667 |
|
2000 |
Rosenkranz S, Ikuno Y, Leong FL, Klinghoffer RA, Miyake S, Band H, Kazlauskas A. Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression. The Journal of Biological Chemistry. 275: 9620-7. PMID 10734113 DOI: 10.1074/jbc.275.13.9620 |
0.395 |
|
1999 |
Tallquist MD, Soriano P, Klinghoffer RA. Growth factor signaling pathways in vascular development Oncogene. 18: 7917-7932. PMID 10630644 DOI: 10.1038/Sj.Onc.1203216 |
0.68 |
|
1999 |
Davy A, Gale NW, Murray EW, Klinghoffer RA, Soriano P, Feuerstein C, Robbins SM. Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. Genes & Development. 13: 3125-35. PMID 10601038 DOI: 10.1101/Gad.13.23.3125 |
0.676 |
|
1999 |
Jones SM, Klinghoffer R, Prestwich GD, Toker A, Kazlauskas A. PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1. Current Biology : Cb. 9: 512-21. PMID 10339426 DOI: 10.1016/S0960-9822(99)80235-8 |
0.405 |
|
1999 |
Klinghoffer RA, Sachsenmaier C, Cooper JA, Soriano P. Src family kinases are required for integrin but not PDGFR signal transduction. The Embo Journal. 18: 2459-71. PMID 10228160 DOI: 10.1093/Emboj/18.9.2459 |
0.648 |
|
1996 |
Quon MJ, Chen H, Lin CH, Zhou L, Ing BL, Zarnowski MJ, Klinghoffer R, Kazlauskas A, Cushman SW, Taylor SI. Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells. Biochemical and Biophysical Research Communications. 226: 587-94. PMID 8831662 DOI: 10.1006/Bbrc.1996.1400 |
0.333 |
|
1996 |
Klinghoffer RA, Duckworth B, Valius M, Cantley L, Kazlauskas A. Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity. Molecular and Cellular Biology. 16: 5905-14. PMID 8816504 DOI: 10.1128/Mcb.16.10.5905 |
0.388 |
|
1995 |
Klinghoffer RA, Kazlauskas A. Identification of a putative Syp substrate, the PDGF beta receptor. The Journal of Biological Chemistry. 270: 22208-17. PMID 7545675 DOI: 10.1074/jbc.270.38.22208 |
0.356 |
|
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