Elaine M. Youngman, Ph.D.

Affiliations: 
2007 Johns Hopkins University, Baltimore, MD 
Area:
translation of the genetic code
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"Elaine Youngman"

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Rachel Green grad student 2007 Johns Hopkins
 (A mechanistic study of peptide bond formation and peptide release on the ribosome.)
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Publications

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Youngman EM, Claycomb JM. (2014) From early lessons to new frontiers: the worm as a treasure trove of small RNA biology. Frontiers in Genetics. 5: 416
Gu W, Lee HC, Chaves D, et al. (2012) CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors. Cell. 151: 1488-500
Lee HC, Gu W, Shirayama M, et al. (2012) C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts. Cell. 150: 78-87
Vasale JJ, Gu W, Thivierge C, et al. (2010) Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3582-7
Gu W, Shirayama M, Conte D, et al. (2009) Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Molecular Cell. 36: 231-44
Brunelle JL, Shaw JJ, Youngman EM, et al. (2008) Peptide release on the ribosome depends critically on the 2' OH of the peptidyl-tRNA substrate. Rna (New York, N.Y.). 14: 1526-31
Youngman EM, McDonald ME, Green R. (2008) Peptide release on the ribosome: mechanism and implications for translational control. Annual Review of Microbiology. 62: 353-73
Youngman EM, He SL, Nikstad LJ, et al. (2007) Stop codon recognition by release factors induces structural rearrangement of the ribosomal decoding center that is productive for peptide release. Molecular Cell. 28: 533-43
Youngman EM, Green R. (2007) Ribosomal translocation: LepA does it backwards. Current Biology : Cb. 17: R136-9
Youngman EM, Cochella L, Brunelle JL, et al. (2006) Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors. Cold Spring Harbor Symposia On Quantitative Biology. 71: 545-9
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