John S. Burg, Ph.D.

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
oxygen sensing, sterol sensing, hypoxic response
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"John Burg"

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Peter J. Espenshade grad student 2011 Johns Hopkins
 (Phosphoregulation of HMG-CoA reductase in fission yeast.)
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Tsutsumi N, Mukherjee S, Waghray D, et al. (2020) Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. Elife. 9
Porter JR, Burg JS, Espenshade PJ, et al. (2012) Identifying a static nonlinear structure in a biological system using noisy, sparse data. Journal of Theoretical Biology. 300: 232-41
Stewart EV, Lloyd SJ, Burg JS, et al. (2012) Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase. The Journal of Biological Chemistry. 287: 672-81
Burg JS, Espenshade PJ. (2011) Regulation of HMG-CoA reductase in mammals and yeast. Progress in Lipid Research. 50: 403-10
Burg JS, Espenshade PJ. (2011) Glucose controls phosphoregulation of hydroxymethylglutaryl coenzyme A reductase through the protein phosphatase 2A-related phosphatase protein, Ppe1, and Insig in fission yeast. The Journal of Biological Chemistry. 286: 27139-46
Porter JR, Iglesias PA, Burg JS, et al. (2011) Overcoming data limitations to identify a static nonlinearity in a biological signaling cascade 2011 45th Annual Conference On Information Sciences and Systems, Ciss 2011
Porter JR, Burg JS, Espenshade PJ, et al. (2010) Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast. The Journal of Biological Chemistry. 285: 41051-61
Burg JS, Powell DW, Chai R, et al. (2008) Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast. Cell Metabolism. 8: 522-31
Burg JS, Bard M, Powell DW, et al. (2007) Insig Regulates HMG‐CoA Reductase by a Non‐Degradative Mechanism in Fission Yeast The Faseb Journal. 21
Todd BL, Stewart EV, Burg JS, et al. (2006) Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Molecular and Cellular Biology. 26: 2817-31
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