Emerson V. Stewart, Ph.D.

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
oxygen sensing, sterol sensing, hypoxic response
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"Emerson Stewart"

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Peter J. Espenshade grad student 2011 Johns Hopkins
 (Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.)
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Publications

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Burr R, Ribbens D, Raychaudhuri S, et al. (2017) Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of Sterol Regulatory Element-binding Protein in fission yeast. The Journal of Biological Chemistry
Burr R, Stewart EV, Espenshade PJ. (2017) Coordinate Regulation of Yeast Sterol Regulatory Element-Binding Protein (SREBP) and Mga2 Transcription Factors. The Journal of Biological Chemistry
Burr R, Stewart EV, Shao W, et al. (2016) Mga2 Transcription Factor Regulates an Oxygen-Responsive Lipid Homeostasis Pathway in Fission Yeast. The Journal of Biological Chemistry
Stewart EV, Lloyd SJ, Burg JS, et al. (2012) Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase. The Journal of Biological Chemistry. 287: 672-81
Stewart EV, Nwosu CC, Tong Z, et al. (2011) Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Molecular Cell. 42: 160-71
Lee CY, Stewart EV, Hughes BT, et al. (2009) Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast. The Embo Journal. 28: 135-43
Hughes AL, Stewart EV, Espenshade PJ. (2008) Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP. Journal of Lipid Research. 49: 2001-12
Stewart EV, Espenshade PJ. (2007) Development of a selection strategy to identify novel genes involved in the S. pombe SREBP pathway. The Faseb Journal. 21
Lee CS, Stewart EV, Espenshade PJ. (2007) Genetic screen to identify regulators of nuclear sterol regulatory element binding protein (SREBP) in fission yeast The Faseb Journal. 21
Todd BL, Stewart EV, Burg JS, et al. (2006) Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Molecular and Cellular Biology. 26: 2817-31
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