Joshua R. Porter, Ph.D.
Affiliations: | 2012 | Johns Hopkins University, Baltimore, MD |
Area:
oxygen sensing, sterol sensing, hypoxic responseGoogle:
"Joshua Porter"Parents
Sign in to add mentor| Peter J. Espenshade | grad student | 2012 | Johns Hopkins | |
| (Control strategies in the fungal hypoxic response: The Sre1 pathway.) | ||||
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Publications
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| Koh WS, Porter JR, Batchelor E. (2019) Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations. Scientific Reports. 9: 5976 |
| Hanson RL, Porter JR, Batchelor E. (2019) Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing. The Journal of Cell Biology |
| Porter JR, Fisher BE, Baranello L, et al. (2017) Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response. Molecular Cell |
| Porter JR, Fisher BE, Batchelor E. (2016) p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks. Cell Systems. 2: 272-82 |
| Porter JR, Batchelor E. (2015) Using computational modeling and experimental synthetic perturbations to probe biological circuits. Methods in Molecular Biology (Clifton, N.J.). 1244: 259-76 |
| Porter JR, Lee CY, Espenshade PJ, et al. (2012) Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation. Molecular Biology of the Cell. 23: 3764-74 |
| Porter JR, Burg JS, Espenshade PJ, et al. (2012) Identifying a static nonlinear structure in a biological system using noisy, sparse data. Journal of Theoretical Biology. 300: 232-41 |
| Porter JR, Iglesias PA, Burg JS, et al. (2011) Overcoming data limitations to identify a static nonlinearity in a biological signaling cascade 2011 45th Annual Conference On Information Sciences and Systems, Ciss 2011 |
| Porter JR, Burg JS, Espenshade PJ, et al. (2010) Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast. The Journal of Biological Chemistry. 285: 41051-61 |