Robertus Antonius de Bruin

MRC LMCB University College London, London, United Kingdom 
Cell cycle, DNA structure checkpoint
"Robertus de Bruin"
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Matthews HK, Bertoli C, de Bruin RAM. (2021) Cell cycle control in cancer. Nature Reviews. Molecular Cell Biology
Bertoli C, de Bruin RAM. (2021) Control of S phase duration: a replication capacity model with E2F transcription at its heart. Molecular & Cellular Oncology. 8: 1839294
Kishkevich A, Cooke SL, Harris MRA, et al. (2019) Gcn5 and Rpd3 have a limited role in the regulation of cell cycle transcripts during the G1 and S phases in Saccharomyces cerevisiae. Scientific Reports. 9: 10686
Pai CC, Kishkevich A, Deegan RS, et al. (2017) Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription. Cell Reports. 20: 2693-2705
Travesa A, Kalashnikova TI, de Bruin RAM, et al. (2017) Correction for Travesa et al., "Repression of G1/S Transcription Is Mediated via Interaction of the GTB Motifs of Nrm1 and Whi5 with Swi6". Molecular and Cellular Biology. 37
Hendler A, Medina EM, Buchler NE, et al. (2017) The evolution of a G1/S transcriptional network in yeasts. Current Genetics
Herlihy AE, de Bruin RA. (2017) The Role of the Transcriptional Response to DNA Replication Stress. Genes. 8
Ledesma-Fernández E, Thorpe PH, de Bruin RA. (2016) Bringing Functional Genomics into Focus. Cell Systems. 3: 214-216
Bertoli C, Herlihy AE, Pennycook BR, et al. (2016) Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage. Cell Reports. 15: 1412-22
Caetano C, Limbo O, Farmer S, et al. (2014) Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability. Cell Reports. 9: 2279-89
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