Kurt W. Runge
Affiliations: | Molecular Genetics | Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States |
Area:
Telomeres, Biology of AgingWebsite:
http://www.lerner.ccf.org/molgen/runge/Google:
"Kurt Runge"Bio:
Ph.D. with Dr. Phillips Robbins on lipid-linked oligosaccharide/asparagine-linked protein glycosylation in budding yeast.
Postdoc with Dr. Virginia Zakian on telomere function in budding yeast.
Current pombe work is on the biology of aging and generating mutant libraries that allow the rapid identification of long-lived mutants.
Cross-listing: Telomere and Telomerase Tree
Parents
Sign in to add mentorPhillips W. Robbins | grad student | 1985 | MIT (Chemistry Tree) | |
(Yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway) | ||||
Virginia A. Zakian | post-doc | Fred Hutchinson Cancer Center (Telomere and Telomerase Tree) |
Children
Sign in to add traineeJinyu Wang | grad student | 2009- | Case Western (Telomere and Telomerase Tree) |
Elizabeth Hulme Berezovsky | post-doc | 2010- | Cleveland Clinic Lerner College of Medicine (Chemistry Tree) |
BETA: Related publications
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Publications
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Zhang H, Kerr C, Audry J, et al. (2024) A Rapidly Inducible DNA Double-Strand Break to Monitor Telomere Formation, DNA Repair, and Checkpoint Activation. Methods in Molecular Biology (Clifton, N.J.). 2862: 209-221 |
Audry J, Zhang H, Kerr C, et al. (2024) Ccq1 restrains Mre11-mediated degradation to distinguish short telomeres from double-strand breaks. Nucleic Acids Research |
Vaurs M, Audry J, Runge KW, et al. (2022) A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells. Nucleic Acids Research |
Li Y, Molyneaux N, Zhang H, et al. (2022) A multiplexed, three-dimensional pooling and next-generation sequencing strategy for creating barcoded mutant arrays: construction of a Schizosaccharomyces pombe transposon insertion library. Nucleic Acids Research |
Irie H, Yamamoto I, Tarumoto Y, et al. (2019) Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast. Plos Genetics. 15: e1008335 |
Rishavy MA, Hallgren KW, Zhang H, et al. (2019) Exon 2 Skipping Eliminates Gamma-Glutamyl Carboxylase Activity, Indicating a Partial Splicing Defect in a Patient with Vitamin K Clotting Factor Deficiency. Journal of Thrombosis and Haemostasis : Jth |
Audry J, Wang J, Eisenstatt JR, et al. (2018) The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2). F1000research. 7: 1027 |
Wang J, Eisenstatt JR, Audry J, et al. (2018) A heterochromatin domain forms gradually at a new telomere and is dynamic at stable telomeres. Molecular and Cellular Biology |
Wang J, Zhang H, Al Shibar M, et al. (2018) Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres. Dna Repair. 65: 26-33 |
Runge KW, Li Y. (2017) A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining. Current Genetics |