Kurt W. Runge
|Molecular Genetics||Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States|
Area:Telomeres, Biology of Aging
Ph.D. with Dr. Phillips Robbins on lipid-linked oligosaccharide/asparagine-linked protein glycosylation in budding yeast.
Postdoc with Dr. Virginia Zakian on telomere function in budding yeast.
Current pombe work is on the biology of aging and generating mutant libraries that allow the rapid identification of long-lived mutants.
Cross-listing: Telomere and Telomerase Tree
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|Rishavy MA, Hallgren KW, Zhang H, et al. (2019) Exon 2 Skipping Eliminates Gamma-Glutamyl Carboxylase Activity, Indicating a Partial Splicing Defect in a Patient with Vitamin K Clotting Factor Deficiency. Journal of Thrombosis and Haemostasis : Jth|
|Audry J, Wang J, Eisenstatt JR, et al. (2018) The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2). F1000research. 7: 1027|
|Wang J, Eisenstatt JR, Audry J, et al. (2018) A heterochromatin domain forms gradually at a new telomere and is dynamic at stable telomeres. Molecular and Cellular Biology|
|Rishavy MA, Hallgren KW, Wilson L, et al. (2018) Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase. Blood|
|Wang J, Zhang H, Al Shibar M, et al. (2018) Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres. Dna Repair. 65: 26-33|
|Runge KW, Li Y. (2017) A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining. Current Genetics|
|Li Y, Wang J, Zhou G, et al. (2017) Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. Genetics|
|Liu Y, Lee IJ, Sun M, et al. (2016) Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis. Molecular Biology of the Cell|
|Corkins ME, May M, Ehrensberger KM, et al. (2013) Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 110: 15371-6|
|Rishavy MA, Hallgren KW, Wilson LA, et al. (2013) The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation. The Journal of Biological Chemistry. 288: 31556-66|