| Year |
Citation |
Score |
| 2021 |
Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle KB, Münch C, Rajalingam K, Randow F, Choudhary C, Dikic I. SIK2 orchestrates actin-dependent host response upon infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33947818 DOI: 10.1073/pnas.2024144118 |
0.407 |
|
| 2021 |
Narita T, Ito S, Higashijima Y, Chu WK, Neumann K, Walter J, Satpathy S, Liebner T, Hamilton WB, Maskey E, Prus G, Shibata M, Iesmantavicius V, Brickman JM, Anastassiadis K, ... ... Choudhary C, et al. Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release. Molecular Cell. PMID 33765415 DOI: 10.1016/j.molcel.2021.03.008 |
0.504 |
|
| 2021 |
Nakamura K, Kustatscher G, Alabert C, Hödl M, Forne I, Völker-Albert M, Satpathy S, Beyer TE, Mailand N, Choudhary C, Imhof A, Rappsilber J, Groth A. Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination. Molecular Cell. PMID 33450211 DOI: 10.1016/j.molcel.2020.12.025 |
0.484 |
|
| 2020 |
Khoa LTP, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, et al. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. PMID 32610040 DOI: 10.1016/J.Stem.2020.06.005 |
0.308 |
|
| 2020 |
Choudhary C, Mann M. Sequencing of the First Draft of the Human Acetylome. Clinical Chemistry. 66: 852-853. PMID 32395753 DOI: 10.1093/Clinchem/Hvaa087 |
0.354 |
|
| 2019 |
MacPherson L, Anokye J, Yeung MM, Lam EYN, Chan YC, Weng CF, Yeh P, Knezevic K, Butler MS, Hoegl A, Chan KL, Burr ML, Gearing LJ, Willson T, Liu J, ... ... Choudhary C, et al. HBO1 is required for the maintenance of leukaemia stem cells. Nature. PMID 31827282 DOI: 10.1038/S41586-019-1835-6 |
0.382 |
|
| 2019 |
Prus G, Hoegl A, Weinert BT, Choudhary C. Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry. Trends in Biochemical Sciences. PMID 31296352 DOI: 10.1016/J.Tibs.2019.06.003 |
0.368 |
|
| 2019 |
Narita T, Weinert BT, Choudhary C. Author Correction: Functions and mechanisms of non-histone protein acetylation. Nature Reviews. Molecular Cell Biology. PMID 31267066 DOI: 10.1038/S41580-019-0156-9 |
0.314 |
|
| 2019 |
Hansen BK, Gupta R, Baldus L, Lyon D, Narita T, Lammers M, Choudhary C, Weinert BT. Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation. Nature Communications. 10: 1055. PMID 30837475 DOI: 10.1038/S41467-019-09024-0 |
0.426 |
|
| 2019 |
Saito M, Hess D, Eglinger J, Fritsch AW, Kreysing M, Weinert BT, Choudhary C, Matthias P. Acetylation of intrinsically disordered regions regulates phase separation. Nature Chemical Biology. 15: 51-61. PMID 30531905 DOI: 10.1038/S41589-018-0180-7 |
0.324 |
|
| 2018 |
Wild T, Budzowska M, Hellmuth S, Eibes S, Karemore G, Barisic M, Stemmann O, Choudhary C. Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint. Cell Reports. 25: 2317-2328.e5. PMID 30485802 DOI: 10.1016/J.Celrep.2018.10.104 |
0.323 |
|
| 2018 |
Narita T, Weinert BT, Choudhary C. Functions and mechanisms of non-histone protein acetylation. Nature Reviews. Molecular Cell Biology. PMID 30467427 DOI: 10.1038/S41580-018-0081-3 |
0.418 |
|
| 2018 |
Camgoz A, Paszkowski-Rogacz M, Satpathy S, Wermke M, Hamann MV, von Bonin M, Choudhary C, Knapp S, Buchholz F. STK3 is a therapeutic target for a subset of acute myeloid leukemias. Oncotarget. 9: 25458-25473. PMID 29876001 DOI: 10.18632/Oncotarget.25238 |
0.535 |
|
| 2018 |
Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, ... Choudhary C, et al. Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome. Cell. PMID 29804834 DOI: 10.1016/J.Cell.2018.04.033 |
0.561 |
|
| 2018 |
Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, Typas D, Lammers M, Mailand N, Nussenzweig A, Lukas J, Choudhary C. DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity. Cell. PMID 29656893 DOI: 10.1016/J.Cell.2018.03.050 |
0.372 |
|
| 2018 |
Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P. p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. Nature Communications. 9: 1017. PMID 29523821 DOI: 10.1038/S41467-018-03417-3 |
0.372 |
|
| 2017 |
Chakraborty D, Paszkowski-Rogacz M, Berger N, Ding L, Mircetic J, Fu J, Iesmantavicius V, Choudhary C, Anastassiadis K, Stewart AF, Buchholz F. lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1. Cell Reports. 21: 3012-3021. PMID 29241531 DOI: 10.1016/J.Celrep.2017.11.045 |
0.368 |
|
| 2017 |
Somyajit K, Gupta R, Sedlackova H, Neelsen KJ, Ochs F, Rask MB, Choudhary C, Lukas J. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science (New York, N.Y.). 358: 797-802. PMID 29123070 DOI: 10.1126/Science.Aao3172 |
0.33 |
|
| 2017 |
Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, ... ... Choudhary C, et al. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. PMID 28953875 DOI: 10.1038/Nature24028 |
0.366 |
|
| 2017 |
Weinert BT, Satpathy S, Hansen BK, Lyon D, Jensen LJ, Choudhary C. Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome. Molecular & Cellular Proteomics : McP. PMID 28254776 DOI: 10.1074/Mcp.M117.067587 |
0.499 |
|
| 2016 |
Thanh Nguyen H, Andrejeva D, Gupta R, Choudhary C, Hong X, Eichhorn PJ, Loya AC, Cohen SM. Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover. Cell Discovery. 2: 16001. PMID 27462448 DOI: 10.1038/Celldisc.2016.1 |
0.36 |
|
| 2016 |
Wagner SA, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes. The Embo Journal. PMID 27307491 DOI: 10.15252/Embj.201694300 |
0.509 |
|
| 2016 |
Silva S, Altmannova V, Luke-Glaser S, Henriksen P, Gallina I, Yang X, Choudhary C, Luke B, Krejci L, Lisby M. Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance. Genes & Development. PMID 26966248 DOI: 10.1101/Gad.276204.115 |
0.362 |
|
| 2016 |
Starnes LM, Su D, Pikkupeura LM, Weinert BT, Santos MA, Mund A, Soria R, Cho YW, Pozdnyakova I, Kubec Højfeldt M, Vala A, Yang W, López-Méndez B, Lee JE, Peng W, ... ... Choudhary C, et al. A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex. Genes & Development. PMID 26744420 DOI: 10.1101/Gad.268797.115 |
0.388 |
|
| 2016 |
Zurnic I, Hütter S, Lehmann U, Stanke N, Reh J, Kern T, Lindel F, Gerresheim G, Hamann M, Müllers E, Lesbats P, Cherepanov P, Serrao E, Engelman A, Lindemann D, ... ... Choudhary C, et al. Proceedings of the Frontiers of Retrovirology Conference 2016 Retrovirology. 13. DOI: 10.1186/S12977-016-0294-5 |
0.371 |
|
| 2015 |
Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F. Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells. Cell Systems. 1: 141-51. PMID 27135800 DOI: 10.1016/J.Cels.2015.08.002 |
0.492 |
|
| 2015 |
Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, Villumsen B, Narita T, Sixma TK, Choudhary C, Bekker-Jensen S, Mailand N. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage. Nature. PMID 26503038 DOI: 10.1038/Nature15401 |
0.37 |
|
| 2015 |
Weinert BT, Moustafa T, Iesmantavicius V, Zechner R, Choudhary C. Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions. The Embo Journal. 34: 2620-32. PMID 26358839 DOI: 10.15252/Embj.201591271 |
0.348 |
|
| 2015 |
Satpathy S, Wagner SA, Beli P, Gupta R, Kristiansen TA, Malinova D, Francavilla C, Tolar P, Bishop GA, Hostager BS, Choudhary C. Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation. Molecular Systems Biology. 11: 810. PMID 26038114 DOI: 10.15252/Msb.20145880 |
0.581 |
|
| 2015 |
Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, Mathiasen DP, Silva S, Hoffmann E, Groth A, Choudhary C, Lisby M. Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nature Communications. 6: 6533. PMID 25817432 DOI: 10.1038/Ncomms7533 |
0.375 |
|
| 2015 |
Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, ... Choudhary C, et al. Acetylation site specificities of lysine deacetylase inhibitors in human cells. Nature Biotechnology. 33: 415-23. PMID 25751058 DOI: 10.1038/Nbt.3130 |
0.507 |
|
| 2015 |
Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C, Hickson ID. FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. Nature Communications. 6: 5931. PMID 25585578 DOI: 10.1038/Ncomms6931 |
0.337 |
|
| 2015 |
Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N. Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage. Molecular Cell. 57: 150-64. PMID 25557546 DOI: 10.1016/J.Molcel.2014.12.001 |
0.357 |
|
| 2015 |
Bursomanno S, Beli P, Khan AM, Minocherhomji S, Wagner SA, Bekker-Jensen S, Mailand N, Choudhary C, Hickson ID, Liu Y. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. Dna Repair. 25: 84-96. PMID 25497329 DOI: 10.1016/J.Dnarep.2014.10.011 |
0.359 |
|
| 2015 |
Acosta-Alvear D, Kampmann M, Cho MY, Wild T, Choudhary C, Shuman MA, Weissman JS, Walter P. Abstract A43: Opposing roles of the 19S regulatory- and 20S core-proteasomal subunits in controlling sensitivity of multiple myeloma cells to proteasome inhibition. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A43 |
0.376 |
|
| 2015 |
Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F. Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells Cell Systems. 1: 141-151. DOI: 10.1016/j.cels.2015.08.002 |
0.35 |
|
| 2014 |
D'Souza RC, Knittle AM, Nagaraj N, van Dinther M, Choudhary C, ten Dijke P, Mann M, Sharma K. Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β. Science Signaling. 7: rs5. PMID 25056879 DOI: 10.1126/Scisignal.2004856 |
0.463 |
|
| 2014 |
Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M. The growing landscape of lysine acetylation links metabolism and cell signalling. Nature Reviews. Molecular Cell Biology. 15: 536-50. PMID 25053359 DOI: 10.1038/Nrm3841 |
0.521 |
|
| 2014 |
Iesmantavicius V, Weinert BT, Choudhary C. Convergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells. Molecular & Cellular Proteomics : McP. 13: 1979-92. PMID 24961812 DOI: 10.1074/Mcp.O113.035683 |
0.451 |
|
| 2014 |
Weinert BT, Iesmantavicius V, Moustafa T, Schölz C, Wagner SA, Magnes C, Zechner R, Choudhary C. Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae. Molecular Systems Biology. 10: 716. PMID 24489116 DOI: 10.1002/Msb.134766 |
0.353 |
|
| 2014 |
Jungmichel S, Sylvestersen KB, Choudhary C, Nguyen S, Mann M, Nielsen ML. Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry. Cell Reports. 6: 578-91. PMID 24462288 DOI: 10.1016/J.Celrep.2013.12.038 |
0.473 |
|
| 2013 |
Villumsen BH, Danielsen JR, Povlsen L, Sylvestersen KB, Merdes A, Beli P, Yang YG, Choudhary C, Nielsen ML, Mailand N, Bekker-Jensen S. A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis. The Embo Journal. 32: 3029-40. PMID 24121310 DOI: 10.1038/Emboj.2013.223 |
0.349 |
|
| 2013 |
Weinert BT, Schölz C, Wagner SA, Iesmantavicius V, Su D, Daniel JA, Choudhary C. Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Reports. 4: 842-51. PMID 23954790 DOI: 10.1016/J.Celrep.2013.07.024 |
0.374 |
|
| 2013 |
Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli. Molecular Cell. 51: 265-72. PMID 23830618 DOI: 10.1016/J.Molcel.2013.06.003 |
0.342 |
|
| 2013 |
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M. OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. Molecular Cell. 50: 818-30. PMID 23806334 DOI: 10.1016/J.Molcel.2013.06.004 |
0.383 |
|
| 2013 |
Poulsen SL, Hansen RK, Wagner SA, van Cuijk L, van Belle GJ, Streicher W, Wikström M, Choudhary C, Houtsmuller AB, Marteijn JA, Bekker-Jensen S, Mailand N. RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response. The Journal of Cell Biology. 201: 797-807. PMID 23751493 DOI: 10.1083/Jcb.201212075 |
0.393 |
|
| 2013 |
Suri V, Paweletz C, Choudhary C. Proteomics Meets Cellular Signaling: Exploring Post-translational Modifications by Mass Spectrometry Science. 340: 499-499. DOI: 10.1126/Science.340.6131.499-C |
0.393 |
|
| 2012 |
Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C. Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3. Plos One. 7: e50545. PMID 23236377 DOI: 10.1371/Journal.Pone.0050545 |
0.41 |
|
| 2012 |
Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Nature Cell Biology. 14: 1089-98. PMID 23000965 DOI: 10.1038/Ncb2579 |
0.386 |
|
| 2012 |
Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Cell Reports. 2: 419-31. PMID 22902405 DOI: 10.1016/J.Celrep.2012.07.006 |
0.353 |
|
| 2012 |
Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 11: 1510-22. PMID 22865919 DOI: 10.1074/Mcp.M112.017251 |
0.43 |
|
| 2012 |
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Molecular & Cellular Proteomics : McP. 11: 1578-85. PMID 22790023 DOI: 10.1074/Mcp.M112.017905 |
0.409 |
|
| 2012 |
Reddy PN, Sargin B, Choudhary C, Stein S, Grez M, Müller-Tidow C, Berdel WE, Serve H, Brandts CH. SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control. Blood. 120: 1691-702. PMID 22517899 DOI: 10.1182/Blood-2010-08-301416 |
0.368 |
|
| 2012 |
Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C. Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Molecular Cell. 46: 212-25. PMID 22424773 DOI: 10.1016/J.Molcel.2012.01.026 |
0.498 |
|
| 2012 |
D'Souza RCJ, Sharma K, Korhonen AMM, Nagaraj N, Choudhary C, Dijke Pt, Mann M. Studying TGF-beta Signaling Using a High Resolution, Quantitative Mass Spectrometric Approach European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)71302-3 |
0.396 |
|
| 2011 |
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Molecular & Cellular Proteomics : McP. 10: M111.013284. PMID 21890473 DOI: 10.1074/Mcp.M111.013284 |
0.505 |
|
| 2011 |
Blasius M, Forment JV, Thakkar N, Wagner SA, Choudhary C, Jackson SP. A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1. Genome Biology. 12: R78. PMID 21851590 DOI: 10.1186/Gb-2011-12-8-R78 |
0.41 |
|
| 2011 |
Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Science Signaling. 4: ra48. PMID 21791702 DOI: 10.1126/Scisignal.2001902 |
0.415 |
|
| 2011 |
Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science (New York, N.Y.). 333: 228-33. PMID 21617041 DOI: 10.1126/Science.1205405 |
0.349 |
|
| 2010 |
Kaidi A, Weinert BT, Choudhary C, Jackson SP. Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science (New York, N.Y.). 329: 1348-53. PMID 20829486 DOI: 10.1126/Science.1192049 |
0.366 |
|
| 2010 |
Gnad F, Ren S, Choudhary C, Cox J, Mann M. Predicting post-translational lysine acetylation using support vector machines. Bioinformatics (Oxford, England). 26: 1666-8. PMID 20505001 DOI: 10.1093/Bioinformatics/Btq260 |
0.477 |
|
| 2010 |
Choudhary C, Mann M. Decoding signalling networks by mass spectrometry-based proteomics. Nature Reviews. Molecular Cell Biology. 11: 427-39. PMID 20461098 DOI: 10.1038/Nrm2900 |
0.501 |
|
| 2009 |
Choudhary C, Olsen JV, Brandts C, Cox J, Reddy PN, Böhmer FD, Gerke V, Schmidt-Arras DE, Berdel WE, Müller-Tidow C, Mann M, Serve H. Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Molecular Cell. 36: 326-39. PMID 19854140 DOI: 10.1016/J.Molcel.2009.09.019 |
0.509 |
|
| 2009 |
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science (New York, N.Y.). 325: 834-40. PMID 19608861 DOI: 10.1126/Science.1175371 |
0.492 |
|
| 2008 |
Tickenbrock L, Hehn S, Sargin B, Choudhary C, Bäumer N, Buerger H, Schulte B, Müller O, Berdel WE, Müller-Tidow C, Serve H. Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4. International Journal of Oncology. 33: 1215-21. PMID 19020754 DOI: 10.3892/Ijo_00000111 |
0.355 |
|
| 2008 |
Tickenbrock L, Hehn S, Sargin B, Evers G, Ng PR, Choudhary C, Berdel WE, Müller-Tidow C, Serve H. Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia. International Journal of Hematology. 88: 174-80. PMID 18668305 DOI: 10.1007/S12185-008-0141-0 |
0.407 |
|
| 2007 |
Sargin B, Choudhary C, Crosetto N, Schmidt MH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, et al. Flt3-dependent transformation by inactivating c-Cbl mutations in AML. Blood. 110: 1004-12. PMID 17446348 DOI: 10.1182/Blood-2007-01-066076 |
0.382 |
|
| 2007 |
Choudhary C, Brandts C, Schwable J, Tickenbrock L, Sargin B, Ueker A, Böhmer FD, Berdel WE, Müller-Tidow C, Serve H. Activation mechanisms of STAT5 by oncogenic Flt3-ITD. Blood. 110: 370-4. PMID 17356133 DOI: 10.1182/Blood-2006-05-024018 |
0.357 |
|
| 2007 |
Sargin B, Bandi SR, August B, Rensinghoff M, Choudhary C, Gonchi PN, Berdel WE, Müller-Tidow C, Serve H. Cbl Mutants Interact with c-Kit and Lead to Factor Independent Growth and Transformation of a Myeloid Cell Line 32D. Blood. 110: 2198-2198. DOI: 10.1182/Blood.V110.11.2198.2198 |
0.306 |
|
| 2006 |
Tickenbrock L, Schwäble J, Strey A, Sargin B, Hehn S, Baas M, Choudhary C, Gerke V, Berdel WE, Müller-Tidow C, Serve H. Wnt signaling regulates transendothelial migration of monocytes. Journal of Leukocyte Biology. 79: 1306-13. PMID 16565323 DOI: 10.1189/Jlb.0905539 |
0.343 |
|
| 2005 |
Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwäble J, Buerger H, Müller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve H. Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation. Cancer Research. 65: 9643-50. PMID 16266983 DOI: 10.1158/0008-5472.Can-05-0422 |
0.385 |
|
| 2005 |
Choudhary C, Müller-Tidow C, Berdel WE, Serve H. Signal transduction of oncogenic Flt3. International Journal of Hematology. 82: 93-9. PMID 16146838 DOI: 10.1532/Ijh97.05090 |
0.393 |
|
| 2005 |
Schmidt-Arras DE, Böhmer A, Markova B, Choudhary C, Serve H, Böhmer FD. Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases. Molecular and Cellular Biology. 25: 3690-703. PMID 15831474 DOI: 10.1128/Mcb.25.9.3690-3703.2005 |
0.376 |
|
| 2005 |
Choudhary C, Schwäble J, Brandts C, Tickenbrock L, Sargin B, Kindler T, Fischer T, Berdel WE, Müller-Tidow C, Serve H. AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations. Blood. 106: 265-73. PMID 15769897 DOI: 10.1182/Blood-2004-07-2942 |
0.367 |
|
| 2005 |
Tickenbrock L, Schwäble J, Wiedehage M, Steffen B, Sargin B, Choudhary C, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction. Blood. 105: 3699-706. PMID 15650056 DOI: 10.1182/Blood-2004-07-2924 |
0.387 |
|
| 2005 |
Schwäble J, Choudhary C, Thiede C, Tickenbrock L, Sargin B, Steur C, Rehage M, Rudat A, Brandts C, Berdel WE, Müller-Tidow C, Serve H. RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation. Blood. 105: 2107-14. PMID 15536149 DOI: 10.1182/Blood-2004-03-0940 |
0.4 |
|
| 2004 |
Tickenbrock L, Schwable J, Wiedehage M, Steffen B, Choudhary C, Berdel WE, Muller-Tidow C, Serve H. Flt3 Internal Tandem Duplications Cooperate with Wnt Signaling in Leukemic Signal Transduction. Blood. 104: 822-822. DOI: 10.1182/Blood.V104.11.822.822 |
0.418 |
|
| 2004 |
Kindler T, Breitenbuecher F, Kasper S, Estey E, Giles F, Feldman E, Ehninger G, Schiller G, Klimek V, Nimer SD, Gratwohl A, Choudhary C, Mueller-Tidow C, Serve H, Gschaidmeier H, et al. Clinical Course and Significance of the Novel FLT3-Y842C Mutation in a Patient with AML Treated with PKC412 Monotherapy. Blood. 104: 2537-2537. DOI: 10.1182/Blood.V104.11.2537.2537 |
0.312 |
|
| 2004 |
Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwable J, Buerger H, Muller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve HL. Constitutive Activation of Akt and mTOR by Flt3 Internal Tandem Duplications Mediates Myeloid Leukemogenesis and Can Be Inhibited by Rapamycin. Blood. 104: 2532-2532. DOI: 10.1182/Blood.V104.11.2532.2532 |
0.393 |
|
| 2003 |
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Böhmer FD, Müller-Tidow C, Berdel WE, Serve H. Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations. Blood. 101: 3164-73. PMID 12468433 DOI: 10.1182/Blood-2002-06-1677 |
0.359 |
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