Xinxin Feng, Ph.D. - Publications

Affiliations: 
2014 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
biomolecular NMR

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bai S, Wang J, Yang K, Zhou C, Xu Y, Song J, Gu Y, Chen Z, Wang M, Shoen C, Andrade B, Cynamon M, Zhou K, Wang H, Cai Q, ... ... Feng X, et al. A polymeric approach toward resistance-resistant antimicrobial agent with dual-selective mechanisms of action. Science Advances. 7. PMID 33571116 DOI: 10.1126/sciadv.abc9917  0.393
2020 Song J, Malwal SR, Baig N, Schurig-Briccio LA, Gao Z, Vaidya GS, Yang K, Abutaleb NS, Seleem MN, Gennis RB, Pogorelov TV, Oldfield E, Feng X. Discovery of Prenyltransferase Inhibitors with and Antibacterial Activity. Acs Infectious Diseases. PMID 33085463 DOI: 10.1021/acsinfecdis.0c00472  0.462
2019 Buter J, Cheng TY, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN, Layre E, Ramnarine AK, Mayfield JA, Young DC, Jezek Martinot A, et al. Mycobacterium tuberculosis releases an antacid that remodels phagosomes. Nature Chemical Biology. 15: 889-899. PMID 31427817 DOI: 10.1038/S41589-019-0336-0  0.48
2019 Song J, Shang N, Baig N, Yao J, Shin C, Kim BK, Li Q, Malwal SR, Oldfield E, Feng X, Guo RT. Aspergillus flavus squalene synthase as an antifungal target: Expression, activity, and inhibition. Biochemical and Biophysical Research Communications. PMID 30904161 DOI: 10.1016/J.Bbrc.2019.03.070  0.468
2018 Malwal SR, O'Dowd B, Feng X, Turhanen PA, Shin CJ, Yao J, Kim BK, Baig N, Zhou T, Bansal S, Khade RL, Zhang Y, Oldfield E. Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways. Journal of the American Chemical Society. PMID 29787268 DOI: 10.1021/Jacs.8B02363  0.486
2017 Boulmier A, Feng X, Oms O, Mialane P, Rivière E, Shin CJ, Yao J, Kubo T, Furuta T, Oldfield E, Dolbecq A. Anticancer Activity of Polyoxometalate-Bisphosphonate Complexes: Synthesis, Characterization, In Vitro and In Vivo Results. Inorganic Chemistry. PMID 28631925 DOI: 10.1021/Acs.Inorgchem.7B01114  0.469
2017 Schwalen CJ, Feng X, Liu W, O-Dowd B, Ko TP, Shin CJ, Guo RT, Mitchell DA, Oldfield E. "Head-to-head" Prenyl Synthases in Some Pathogenic Bacteria. Chembiochem : a European Journal of Chemical Biology. PMID 28340291 DOI: 10.1002/Cbic.201700099  0.512
2016 Wang Y, Desai J, Zhang Y, Malwal SR, Shin CJ, Feng X, Sun H, Liu G, Guo RT, Oldfield E. Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase. Chemmedchem. PMID 27578312 DOI: 10.1002/Cmdc.201600342  0.512
2016 Bai Y, Feng X, Xing H, Xu Y, Kim BK, Baig N, Zhou T, Gewirth AA, Lu Y, Oldfield E, Zimmerman SC. A Highly Efficient Single-Chain Metal-Organic Nanoparticle Catalyst for Alkyne-Azide "Click" Reactions in Water and in Cells. Journal of the American Chemical Society. PMID 27529791 DOI: 10.1021/Jacs.6B04477  0.406
2016 Zhang L, Chen CC, Ko TP, Huang JW, Zheng Y, Liu W, Wang I, Malwal SR, Feng X, Wang K, Huang CH, Hsu SD, Wang AH, Oldfield E, Guo RT. Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angewandte Chemie (International Ed. in English). PMID 26954060 DOI: 10.1002/Anie.201511388  0.499
2016 Liu M, Chen CC, Chen L, Xiao X, Zheng Y, Huang JW, Liu W, Ko TP, Cheng YS, Feng X, Oldfield E, Guo RT, Ma Y. Structure and Function of a "Head-to-Middle" Prenyltransferase: Lavandulyl Diphosphate Synthase. Angewandte Chemie (International Ed. in English). PMID 26922900 DOI: 10.1002/Anie.201600656  0.502
2016 Li XF, Cao RB, Luo J, Fan JM, Wang JM, Zhang YP, Gu JY, Feng XL, Zhou B, Chen PY. MicroRNA transcriptome profiling of mice brains infected with Japanese encephalitis virus by RNA sequencing. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. PMID 26845346 DOI: 10.1016/j.meegid.2016.01.028  0.309
2016 Xia Y, Liu Z, Yan S, Yin F, Feng X, Liu BF. Identifying multiple bacterial pathogens by loop-mediated isothermal amplification on a rotate & react slipchip Sensors and Actuators, B: Chemical. 228: 491-499. DOI: 10.1016/j.snb.2016.01.074  0.444
2016 Liu M, Chen C, Chen L, Xiao X, Zheng Y, Huang J, Liu W, Ko T, Cheng Y, Feng X, Oldfield E, Guo R, Ma Y. Cover Picture: Structure and Function of a “Head-to-Middle” Prenyltransferase: Lavandulyl Diphosphate Synthase (Angew. Chem. Int. Ed. 15/2016) Angewandte Chemie International Edition. 55: 4613-4613. DOI: 10.1002/Anie.201602065  0.482
2016 Liu M, Chen C, Chen L, Xiao X, Zheng Y, Huang J, Liu W, Ko T, Cheng Y, Feng X, Oldfield E, Guo R, Ma Y. Titelbild: Structure and Function of a “Head-to-Middle” Prenyltransferase: Lavandulyl Diphosphate Synthase (Angew. Chem. 15/2016) Angewandte Chemie. 128: 4689-4689. DOI: 10.1002/Ange.201602065  0.485
2015 Hu Y, Liu W, Malwal SR, Zheng Y, Feng X, Ko TP, Chen CC, Xu Z, Liu M, Han X, Gao J, Oldfield E, Guo RT. Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms. Angewandte Chemie (International Ed. in English). 54: 15478-82. PMID 26768532 DOI: 10.1002/Anie.201508310  0.49
2015 Feng X, Zhu W, Schurig-Briccio LA, Lindert S, Shoen C, Hitchings R, Li J, Wang Y, Baig N, Zhou T, Kim BK, Crick DC, Cynamon M, McCammon JA, Gennis RB, et al. Antiinfectives targeting enzymes and the proton motive force. Proceedings of the National Academy of Sciences of the United States of America. 112: E7073-82. PMID 26644565 DOI: 10.1073/Pnas.1521988112  0.673
2015 Li J, Feng X, Zhu W, Oskolkov N, Zhou T, Kim BK, Baig N, McMahon MT, Oldfield E. Chemical Exchange Saturation Transfer (CEST) Agents: Quantum Chemistry and MRI. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26616530 DOI: 10.1002/Chem.201503942  0.673
2015 Kim MO, Feng X, Feixas F, Zhu W, Lindert S, Bogue S, Sinko W, de Oliveira C, Rao G, Oldfield E, McCammon JA. A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery. Chemical Biology & Drug Design. 85: 756-69. PMID 25352216 DOI: 10.1111/Cbdd.12463  0.508
2015 Han X, Chen CC, Kuo CJ, Huang CH, Zheng Y, Ko TP, Zhu Z, Feng X, Wang K, Oldfield E, Wang AH, Liang PH, Guo RT, Ma Y. Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. Proteins. 83: 37-45. PMID 24895191 DOI: 10.1002/Prot.24618  0.506
2015 Hu Y, Liu W, Malwal SR, Zheng Y, Feng X, Ko T, Chen C, Xu Z, Liu M, Han X, Gao J, Oldfield E, Guo R. Cover Picture: Structures of Iridoid Synthase fromCantharanthus roseuswith Bound NAD+, NADPH, or NAD+/10-Oxogeranial: Reaction Mechanisms (Angew. Chem. Int. Ed. 51/2015) Angewandte Chemie International Edition. 54: 15301-15301. DOI: 10.1002/Anie.201510890  0.493
2015 Hu Y, Liu W, Malwal SR, Zheng Y, Feng X, Ko T, Chen C, Xu Z, Liu M, Han X, Gao J, Oldfield E, Guo R. Titelbild: Structures of Iridoid Synthase fromCantharanthus roseuswith Bound NAD+, NADPH, or NAD+/10-Oxogeranial: Reaction Mechanisms (Angew. Chem. 51/2015) Angewandte Chemie. 127: 15517-15517. DOI: 10.1002/Ange.201510890  0.494
2014 Oldfield E, Feng X. Resistance-resistant antibiotics. Trends in Pharmacological Sciences. 35: 664-74. PMID 25458541 DOI: 10.1016/J.Tips.2014.10.007  0.483
2014 Feng X, Hu Y, Zheng Y, Zhu W, Li K, Huang CH, Ko TP, Ren F, Chan HC, Nega M, Bogue S, López D, Kolter R, Götz F, Guo RT, et al. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production. Chemistry & Biology. 21: 1557-63. PMID 25308276 DOI: 10.1016/J.Chembiol.2014.08.018  0.497
2014 Liu W, Feng X, Zheng Y, Huang CH, Nakano C, Hoshino T, Bogue S, Ko TP, Chen CC, Cui Y, Li J, Wang I, Hsu ST, Oldfield E, Guo RT. Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum. Scientific Reports. 4: 6214. PMID 25269599 DOI: 10.1038/Srep06214  0.522
2014 Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, et al. Multitarget drug discovery for tuberculosis and other infectious diseases. Journal of Medicinal Chemistry. 57: 3126-39. PMID 24568559 DOI: 10.1021/Jm500131S  0.653
2014 Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, et al. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. Journal of the American Chemical Society. 136: 2892-6. PMID 24475925 DOI: 10.1021/Ja413127V  0.546
2013 Ren F, Feng X, Ko TP, Huang CH, Hu Y, Chan HC, Liu YL, Wang K, Chen CC, Pang X, He M, Li Y, Oldfield E, Guo RT. Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus. Chembiochem : a European Journal of Chemical Biology. 14: 195-9. PMID 23322418 DOI: 10.1002/Cbic.201200748  0.53
2013 Ren F, Feng X, Ko T, Huang C, Hu Y, Chan H, Liu Y, Wang K, Chen C, Pang X, He M, Li Y, Oldfield E, Guo R. Cover Picture: Insights into TIM-Barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB fromBacillus subtilisandStaphylococcus aureus(ChemBioChem 2/2013) Chembiochem. 14: 165-165. DOI: 10.1002/Cbic.201390000  0.485
2012 Ren F, Ko TP, Feng X, Huang CH, Chan HC, Hu Y, Wang K, Ma Y, Liang PH, Wang AH, Oldfield E, Guo RT. Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes. Angewandte Chemie (International Ed. in English). 51: 4157-60. PMID 22431288 DOI: 10.1002/Anie.201108002  0.515
2012 No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 4058-63. PMID 22392982 DOI: 10.1073/Pnas.1118215109  0.673
2012 Ren F, Ko T, Feng X, Huang C, Chan H, Hu Y, Wang K, Ma Y, Liang P, Wang AH, Oldfield E, Guo R. Back Cover: Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes (Angew. Chem. Int. Ed. 17/2012) Angewandte Chemie International Edition. 51: 4240-4240. DOI: 10.1002/Anie.201201339  0.518
2012 Ren F, Ko T, Feng X, Huang C, Chan H, Hu Y, Wang K, Ma Y, Liang P, Wang AH, Oldfield E, Guo R. Rücktitelbild: Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes (Angew. Chem. 17/2012) Angewandte Chemie. 124: 4314-4314. DOI: 10.1002/Ange.201201339  0.516
2001 Ando S, Sarlis NJ, Krishnan J, Feng X, Refetoff S, Zhang MQ, Oldfield EH, Yen PM. Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. Molecular Endocrinology (Baltimore, Md.). 15: 1529-38. PMID 11518802 DOI: 10.1210/Mend.15.9.0687  0.337
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