Hugh Willet Brock - Publications

Affiliations: 
 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McKeon J, Brock HW. Interactions of thePolycomb group of genes with homeotic loci ofDrosophila. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 199: 387-396. PMID 28305613 DOI: 10.1007/BF01705848  0.339
2020 McKeon J, Brock HW. Interactions of thePolycomb group of genes with homeotic loci ofDrosophila. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 199: 387-396. PMID 28305613 DOI: 10.1007/BF01705848  0.339
2017 Li T, Hodgson JW, Petruk S, Mazo A, Brock HW. Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. Epigenetics & Chromatin. 10: 43. PMID 28927461 DOI: 10.1186/s13072-017-0151-3  0.629
2017 Petruk S, Cai J, Sussman R, Sun G, Kovermann SK, Mariani SA, Calabretta B, McMahon SB, Brock HW, Iacovitti L, Mazo A. Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation. Molecular Cell. PMID 28410996 DOI: 10.1016/J.Molcel.2017.03.006  0.406
2016 L Black K, Petruk S, Fenstermaker TK, Hodgson JW, Caplan JL, Brock HW, Mazo A. Chromatin proteins and RNA are associated with DNA during all phases of mitosis. Cell Discovery. 2: 16038. PMID 27807477 DOI: 10.1038/Celldisc.2016.38  0.592
2015 Dupont CA, Dardalhon-Cuménal D, Kyba M, Brock HW, Randsholt NB, Peronnet F. Drosophila Cyclin G and epigenetic maintenance of gene expression during development. Epigenetics & Chromatin. 8: 18. PMID 25995770 DOI: 10.1186/s13072-015-0008-6  0.475
2013 Petruk S, Black KL, Kovermann SK, Brock HW, Mazo A. Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nature Communications. 4: 2841. PMID 24276476 DOI: 10.1038/ncomms3841  0.378
2013 Yasunaga S, Ohtsubo M, Ohno Y, Saeki K, Kurogi T, Tanaka-Okamoto M, Ishizaki H, Shirai M, Mihara K, Brock HW, Miyoshi J, Takihara Y. Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4. Molecular and Cellular Biology. 33: 644-60. PMID 23207902 DOI: 10.1128/MCB.00974-12  0.427
2012 Petruk S, Sedkov Y, Johnston DM, Hodgson JW, Black KL, Kovermann SK, Beck S, Canaani E, Brock HW, Mazo A. TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell. 150: 922-33. PMID 22921915 DOI: 10.1016/J.Cell.2012.06.046  0.682
2012 Mohd-Sarip A, Lagarou A, Doyen CM, van der Knaap JA, Aslan Ãœ, Bezstarosti K, Yassin Y, Brock HW, Demmers JA, Verrijzer CP. Transcription-independent function of Polycomb group protein PSC in cell cycle control. Science (New York, N.Y.). 336: 744-7. PMID 22491092 DOI: 10.1126/science.1215927  0.43
2011 Hodgson JW, Brock HW. Are polycomb group bodies gene silencing factories? Cell. 144: 170-1. PMID 21241887 DOI: 10.1016/j.cell.2011.01.006  0.624
2010 Beck S, Faradji F, Brock H, Peronnet F. Maintenance of Hox gene expression patterns. Advances in Experimental Medicine and Biology. 689: 41-62. PMID 20795321 DOI: 10.1007/978-1-4419-6673-5_3  0.642
2010 Beck SA, Falconer E, Catching A, Hodgson JW, Brock HW. Cell cycle defects in polyhomeotic mutants are caused by abrogation of the DNA damage checkpoint. Developmental Biology. 339: 320-8. PMID 20045683 DOI: 10.1016/j.ydbio.2009.12.031  0.709
2010 Fisher CL, Pineault N, Brookes C, Helgason CD, Ohta H, Bodner C, Hess JL, Humphries RK, Brock HW. Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia. Blood. 115: 38-46. PMID 19861679 DOI: 10.1182/blood-2009-07-230698  0.431
2010 Fisher CL, Lee I, Bloyer S, Bozza S, Chevalier J, Dahl A, Bodner C, Helgason CD, Hess JL, Humphries RK, Brock HW. Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Developmental Biology. 337: 9-15. PMID 19833123 DOI: 10.1016/j.ydbio.2009.10.004  0.477
2009 Sinclair DA, Syrzycka M, Macauley MS, Rastgardani T, Komljenovic I, Vocadlo DJ, Brock HW, Honda BM. Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). Proceedings of the National Academy of Sciences of the United States of America. 106: 13427-32. PMID 19666537 DOI: 10.1073/Pnas.0904638106  0.386
2009 Brock HW, Hodgson JW, Petruk S, Mazo A. Regulatory noncoding RNAs at Hox loci. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 27-34. PMID 19234521 DOI: 10.1139/O08-108  0.583
2008 Hallson G, Syrzycka M, Beck SA, Kennison JA, Dorsett D, Page SL, Hunter SM, Keall R, Warren WD, Brock HW, Sinclair DA, Honda BM. The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 12405-10. PMID 18713858 DOI: 10.1073/pnas.0801698105  0.647
2008 Kim K, Choi J, Heo K, Kim H, Levens D, Kohno K, Johnson EM, Brock HW, An W. Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription. The Journal of Biological Chemistry. 283: 9113-26. PMID 18258596 DOI: 10.1074/Jbc.M708205200  0.351
2007 Mazo A, Hodgson JW, Petruk S, Sedkov Y, Brock HW. Transcriptional interference: an unexpected layer of complexity in gene regulation. Journal of Cell Science. 120: 2755-61. PMID 17690303 DOI: 10.1242/jcs.007633  0.586
2007 Petruk S, Sedkov Y, Brock HW, Mazo A. A model for initiation of mosaic HOX gene expression patterns by non-coding RNAs in early embryos. Rna Biology. 4: 1-6. PMID 17568198 DOI: 10.4161/Rna.4.1.4300  0.416
2006 Petruk S, Sedkov Y, Riley KM, Hodgson J, Schweisguth F, Hirose S, Jaynes JB, Brock HW, Mazo A. Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference. Cell. 127: 1209-21. PMID 17174895 DOI: 10.1016/j.cell.2006.10.039  0.61
2006 Fisher CL, Randazzo F, Humphries RK, Brock HW. Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family. Gene. 369: 109-18. PMID 16412590 DOI: 10.1016/j.gene.2005.10.033  0.433
2006 O'Dor E, Beck SA, Brock HW. Polycomb group mutants exhibit mitotic defects in syncytial cell cycles of Drosophila embryos. Developmental Biology. 290: 312-22. PMID 16388795 DOI: 10.1016/j.ydbio.2005.11.015  0.624
2005 Milne TA, Martin ME, Brock HW, Slany RK, Hess JL. Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications. Cancer Research. 65: 11367-74. PMID 16357144 DOI: 10.1158/0008-5472.CAN-05-1041  0.404
2005 Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. MLL associates specifically with a subset of transcriptionally active target genes. Proceedings of the National Academy of Sciences of the United States of America. 102: 14765-70. PMID 16199523 DOI: 10.1073/pnas.0503630102  0.412
2005 Brock HW, Fisher CL. Maintenance of gene expression patterns. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 633-55. PMID 15704101 DOI: 10.1002/dvdy.20298  0.452
2003 Wang YJ, Brock HW. Polyhomeotic stably associates with molecular chaperones Hsc4 and Droj2 in Drosophila Kc1 cells. Developmental Biology. 262: 350-60. PMID 14550797 DOI: 10.1016/S0012-1606(03)00396-8  0.359
2003 Martin ME, Milne TA, Bloyer S, Galoian K, Shen W, Gibbs D, Brock HW, Slany R, Hess JL. Dimerization of MLL fusion proteins immortalizes hematopoietic cells. Cancer Cell. 4: 197-207. PMID 14522254 DOI: 10.1016/S1535-6108(03)00214-9  0.345
2003 Bloyer S, Cavalli G, Brock HW, Dura JM. Identification and characterization of polyhomeotic PREs and TREs. Developmental Biology. 261: 426-42. PMID 14499651 DOI: 10.1016/S0012-1606(03)00314-2  0.405
2003 Fisher CL, Berger J, Randazzo F, Brock HW. A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11. Gene. 306: 115-26. PMID 12657473 DOI: 10.1016/S0378-1119(03)00430-X  0.362
2002 Milne TA, Briggs SD, Brock HW, Martin ME, Gibbs D, Allis CD, Hess JL. MLL targets SET domain methyltransferase activity to Hox gene promoters. Molecular Cell. 10: 1107-17. PMID 12453418 DOI: 10.1016/S1097-2765(02)00741-4  0.434
2001 Hodgson JW, Argiropoulos B, Brock HW. Site-specific recognition of a 70-base-pair element containing d(GA)(n) repeats mediates bithoraxoid polycomb group response element-dependent silencing. Molecular and Cellular Biology. 21: 4528-43. PMID 11416132 DOI: 10.1128/MCB.21.14.4528-4543.2001  0.726
2001 Dietrich BH, Moore J, Kyba M, dosSantos G, McCloskey F, Milne TA, Brock HW, Krause HM. Tantalus, a novel ASX-interacting protein with tissue-specific functions. Developmental Biology. 234: 441-53. PMID 11397012 DOI: 10.1006/Dbio.2001.0255  0.461
2001 Brock HW, van Lohuizen M. The Polycomb group--no longer an exclusive club? Current Opinion in Genetics & Development. 11: 175-81. PMID 11250141 DOI: 10.1016/S0959-437X(00)00176-3  0.4
1999 Tomotsune D, Takihara Y, Berger J, Duhl D, Joo S, Kyba M, Shirai M, Ohta H, Matsuda Y, Honda BM, Simon J, Shimada K, Brock HW, Randazzo F. A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro. Differentiation; Research in Biological Diversity. 65: 229-39. PMID 10653359 DOI: 10.1046/J.1432-0436.1999.6540229.X  0.465
1999 Pfeifer TA, Hegedus D, Wang YJ, Zhao Y, Meredith J, Brock HW, Phillips JE, Grigliatti TA, Theilmann DA. Analysis of an insect neuropeptide, Schistocerca gregaria ion transport peptide (ITP), expressed in insect cell systems. Archives of Insect Biochemistry and Physiology. 42: 245-52. PMID 10578114 DOI: 10.1002/(SICI)1520-6327(199912)42:4<245::AID-ARCH3>3.0.CO;2-W  0.557
1999 Berger J, Kurahashi H, Takihara Y, Shimada K, Brock HW, Randazzo F. The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34. Gene. 237: 185-91. PMID 10524249 DOI: 10.1016/S0378-1119(99)00285-1  0.399
1999 Milne TA, Sinclair DA, Brock HW. The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs. Molecular & General Genetics : Mgg. 261: 753-61. PMID 10394912 DOI: 10.1007/s004380050018  0.454
1998 Clegg NJ, Honda BM, Whitehead IP, Grigliatti TA, Wakimoto B, Brock HW, Lloyd VK, Sinclair DA. Suppressors of position-effect variegation in Drosophila melanogaster affect expression of the heterochromatic gene light in the absence of a chromosome rearrangement. Genome / National Research Council Canada = Gã©Nome / Conseil National De Recherches Canada. 41: 495-503. PMID 9796098 DOI: 10.1139/G98-041  0.659
1998 Stankunas K, Berger J, Ruse C, Sinclair DA, Randazzo F, Brock HW. The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals. Development (Cambridge, England). 125: 4055-66. PMID 9735366  0.335
1998 Salinas CA, Sinclair DA, O'Hare K, Brock HW. Characterization of a Drosophila homologue of the 160-kDa subunit of the cleavage and polyadenylation specificity factor CPSF. Molecular & General Genetics : Mgg. 257: 672-80. PMID 9604891 DOI: 10.1007/s004380050696  0.41
1998 Hashimoto N, Brock HW, Nomura M, Kyba M, Hodgson J, Fujita Y, Takihara Y, Shimada K, Higashinakagawa T. RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes. Biochemical and Biophysical Research Communications. 245: 356-65. PMID 9571155 DOI: 10.1006/bbrc.1998.8438  0.586
1998 Kyba M, Brock HW. The Drosophila polycomb group protein Psc contacts ph and Pc through specific conserved domains. Molecular and Cellular Biology. 18: 2712-20. PMID 9566890 DOI: 10.1128/Mcb.18.5.2712  0.353
1998 Kyba M, Brock HW. The SAM domain of polyhomeotic, RAE28, and scm mediates specific interactions through conserved residues. Developmental Genetics. 22: 74-84. PMID 9499582 DOI: 10.1002/(SICI)1520-6408(1998)22:1<74::AID-DVG8>3.0.CO;2-4  0.306
1998 Sinclair DA, Milne TA, Hodgson JW, Shellard J, Salinas CA, Kyba M, Randazzo F, Brock HW. The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes. Development (Cambridge, England). 125: 1207-16. PMID 9477319  0.623
1998 Sinclair DA, Clegg NJ, Antonchuk J, Milne TA, Stankunas K, Ruse C, Grigliatti TA, Kassis JA, Brock HW. Enhancer of Polycomb is a suppressor of position-effect variegation in Drosophila melanogaster. Genetics. 148: 211-20. PMID 9475733  0.629
1997 Hodgson JW, Cheng NN, Sinclair DA, Kyba M, Randsholt NB, Brock HW. The polyhomeotic locus of Drosophila melanogaster is transcriptionally and post-transcriptionally regulated during embryogenesis. Mechanisms of Development. 66: 69-81. PMID 9376325 DOI: 10.1016/S0925-4773(97)00091-9  0.633
1995 Campbell RB, Sinclair DA, Couling M, Brock HW. Genetic interactions and dosage effects of Polycomb group genes of Drosophila. Molecular & General Genetics : Mgg. 246: 291-300. PMID 7854314 DOI: 10.1007/BF00288601  0.441
1995 Serrano N, Brock HW, Demeret C, Dura JM, Randsholt NB, Kornberg TB, Maschat F. polyhomeotic appears to be a target of engrailed regulation in Drosophila. Development (Cambridge, England). 121: 1691-703. PMID 7600986  0.323
1994 Landecker HL, Sinclair DA, Brock HW. Screen for enhancers of Polycomb and Polycomblike in Drosophila melanogaster. Developmental Genetics. 15: 425-34. PMID 7955568 DOI: 10.1002/dvg.1020150505  0.459
1994 McKeon J, Slade E, Sinclair DA, Cheng N, Couling M, Brock HW. Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes. Molecular & General Genetics : Mgg. 244: 474-83. PMID 7915818 DOI: 10.1007/BF00583898  0.45
1992 Franke A, DeCamillis M, Zink D, Cheng N, Brock HW, Paro R. Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster. The Embo Journal. 11: 2941-50. PMID 1353445 DOI: 10.1002/J.1460-2075.1992.Tb05364.X  0.333
1992 Sinclair DA, Campbell RB, Nicholls F, Slade E, Brock HW. Genetic analysis of the additional sex combs locus of Drosophila melanogaster. Genetics. 130: 817-25. PMID 1349871  0.376
1992 DeCamillis M, Cheng NS, Pierre D, Brock HW. The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes & Development. 6: 223-32. PMID 1346609 DOI: 10.1101/Gad.6.2.223  0.439
1991 Deatrick J, Daly M, Randsholt NB, Brock HW. The complex genetic locus polyhomeotic in Drosophila melanogaster potentially encodes two homologous zinc-finger proteins. Gene. 105: 185-95. PMID 1937015 DOI: 10.1016/0378-1119(91)90150-A  0.42
1989 Good AG, Meister GA, Brock HW, Grigliatti TA, Hickey DA. Rapid spread of transposable p elements in experimental populations of Drosophila melanogaster. Genetics. 122: 387-96. PMID 17246499  0.556
1988 Dura JM, Deatrick J, Randsholt NB, Brock HW, Santamaria P. Maternal and zygotic requirement for thepolyhomeotic complex genetic locus inDrosophila. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 197: 239-246. PMID 28305632 DOI: 10.1007/BF02439431  0.607
1988 Dura JM, Deatrick J, Randsholt NB, Brock HW, Santamaria P. Maternal and zygotic requirement for the polyhomeotic complex genetic locus in Drosophila Roux's Archives of Developmental Biology. 197: 239-246. DOI: 10.1007/BF02439431  0.509
1987 Brock HW. Sequence and genomic structure of ras homologues Dmras85D and Dmras64B of Drosophila melanogaster. Gene. 51: 129-37. PMID 3110012 DOI: 10.1016/0378-1119(87)90301-5  0.307
1987 Dura JM, Randsholt NB, Deatrick J, Erk I, Santamaria P, Freeman JD, Freeman SJ, Weddell D, Brock HW. A complex genetic locus, polyhomeotic, is required for segmental specification and epidermal development in D. melanogaster. Cell. 51: 829-39. PMID 2890438 DOI: 10.1016/0092-8674(87)90106-1  0.605
1987 Lansman RA, Shade RO, Grigliatti TA, Brock HW. Evolution of P transposable elements: sequences of Drosophila nebulosa P elements. Proceedings of the National Academy of Sciences of the United States of America. 84: 6491-5. PMID 2819880 DOI: 10.1073/Pnas.84.18.6491  0.584
1986 Stacey SN, Lansman RA, Brock HW, Grigliatti TA. Distribution and conservation of mobile elements in the genus Drosophila. Molecular Biology and Evolution. 3: 522-34. PMID 2832695  0.56
1985 Dura JM, Brock HW, Santamaria P. Polyhomeotic: a gene of Drosophila melanogaster required for correct expression of segmental identity. Molecular & General Genetics : Mgg. 198: 213-20. PMID 3920476 DOI: 10.1007/BF00382998  0.579
1985 Moreau J, Kejzlarova-Lepesant J, Brock H, Lepesant JA, Scherrer K. AT-rich linkers in long range organisation of Drosophila DNA. Molecular & General Genetics : Mgg. 199: 357-64. PMID 2993787 DOI: 10.1007/Bf00330743  0.35
1985 Lansman RA, Stacey SN, Grigliatti TA, Brock HW. Sequences homologous to the P mobile element of Drosophila melanogaster are widely distributed in the subgenus Sophophora Nature. 318: 561-563. DOI: 10.1038/318561a0  0.595
1984 Powell D, Sato JD, Brock HW, Roberts DB. Regulation of synthesis of the larval serum proteins of Drosophila melanogaster. Developmental Biology. 102: 206-15. PMID 6199241 DOI: 10.1016/0012-1606(84)90185-4  0.311
1984 Kejzlarová-Lepesant J, Brock HW, Moreau J, Dubertret ML, Billault A, Lepesant JA. A complete and a truncated U1 snRNA gene of Drosophila melanogaster are found as inverted repeats at region 82E of the polytene chromosomes. Nucleic Acids Research. 12: 8835-46. PMID 6083546 DOI: 10.1093/nar/12.23.8835  0.357
Show low-probability matches.