Nevan J. Krogan - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Website:
http://kroganlab.ucsf.edu/

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 31101715 DOI: 10.1073/pnas.1904516116  0.32
2019 Ali I, Ruiz DG, Ni Z, Johnson JR, Zhang H, Li PC, Khalid MM, Conrad RJ, Guo X, Min J, Greenblatt J, Jacobson M, Krogan NJ, Ott M. Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. Molecular Cell. PMID 31054975 DOI: 10.1016/j.molcel.2019.04.008  0.68
2018 Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, ... ... Krogan NJ, et al. Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. Cell. 175: 1931-1945.e18. PMID 30550790 DOI: 10.1016/j.cell.2018.11.028  0.44
2018 Meza Gutierrez F, Simsek D, Mizrak A, Deutschbauer A, Braberg H, Johnson J, Xu J, Shales M, Nguyen M, Tamse-Kuehn R, Palm C, Steinmetz LM, Krogan NJ, Toczyski DP. Genetic analysis reveals functions of atypical polyubiquitin chains. Elife. 7. PMID 30547882 DOI: 10.7554/eLife.42955  0.44
2018 Penn BH, Netter Z, Johnson JR, Von Dollen J, Jang GM, Johnson T, Ohol YM, Maher C, Bell SL, Geiger K, Golovkine G, Du X, Choi A, Parry T, Mohapatra BC, ... ... Krogan NJ, et al. An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses. Molecular Cell. 71: 637-648.e5. PMID 30118682 DOI: 10.1016/j.molcel.2018.07.010  0.44
2018 Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, ... ... Krogan NJ, et al. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 174: 505-520. PMID 30053424 DOI: 10.1016/j.cell.2018.06.016  0.44
2018 Streubel G, Watson A, Jammula SG, Scelfo A, Fitzpatrick DJ, Oliviero G, McCole R, Conway E, Glancy E, Negri GL, Dillon E, Wynne K, Pasini D, Krogan NJ, Bracken AP, et al. The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells. Molecular Cell. PMID 29606589 DOI: 10.1016/j.molcel.2018.02.027  0.44
2017 Espinosa-Cantú A, Ascencio D, Herrera-Basurto S, Xu J, Roguev A, Krogan NJ, DeLuna A. Protein Moonlighting Revealed by Non-catalytic Phenotypes of Yeast Enzymes. Genetics. PMID 29127264 DOI: 10.1534/genetics.117.300377  0.6
2017 Roguev A, Xu J, Krogan N. DNA Preparation from Schizosaccharomyces pombe. Cold Spring Harbor Protocols. PMID 28733411 DOI: 10.1101/pdb.prot091959  0.6
2017 Roguev A, Ryan CJ, Hartsuiker E, Krogan NJ. High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe. Cold Spring Harbor Protocols. PMID 28733404 DOI: 10.1101/pdb.top079905  0.6
2017 Roguev A, Xu J, Krogan N. Transformation of Schizosaccharomyces pombe in a 96-Well Format. Cold Spring Harbor Protocols. PMID 28733397 DOI: 10.1101/pdb.prot091942  0.6
2017 Du D, Roguev A, Gordon DE, Chen M, Chen SH, Shales M, Shen JP, Ideker T, Mali P, Qi LS, Krogan NJ. Genetic interaction mapping in mammalian cells using CRISPR interference. Nature Methods. PMID 28481362 DOI: 10.1038/nmeth.4286  0.6
2017 Nissen KE, Homer CM, Ryan CJ, Shales M, Krogan NJ, Patrick KL, Guthrie C. The histone variant H2A.Z promotes splicing of weak introns. Genes & Development. 31: 688-701. PMID 28446597 DOI: 10.1101/gad.295287.116  0.44
2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, ... Krogan NJ, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/j.chom.2016.11.001  0.32
2016 Ball KA, Johnson JR, Lewinski MK, Guatelli J, Verschueren E, Krogan NJ, Jacobson MP. Non-degradative Ubiquitination of Protein Kinases. Plos Computational Biology. 12: e1004898. PMID 27253329 DOI: 10.1371/journal.pcbi.1004898  0.72
2016 Janke R, Kong J, Braberg H, Cantin G, Yates JR, Krogan NJ, Heyer WD. Nonsense-mediated decay regulates key components of homologous recombination. Nucleic Acids Research. PMID 27001511 DOI: 10.1093/nar/gkw182  0.44
2016 Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, ... ... Krogan NJ, et al. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. PMID 26971820 DOI: 10.1016/j.stem.2016.01.022  0.32
2015 Costa HA, Leitner MG, Sos ML, Mavrantoni A, Rychkova A, Johnson JR, Newton BW, Yee MC, De La Vega FM, Ford JM, Krogan NJ, Shokat KM, Oliver D, Halaszovich CR, Bustamante CD. Discovery and functional characterization of a neomorphic PTEN mutation. Proceedings of the National Academy of Sciences of the United States of America. 112: 13976-81. PMID 26504226 DOI: 10.1073/pnas.1422504112  0.32
2015 Johnson JR, Santos SD, Johnson T, Pieper U, Strumillo M, Wagih O, Sali A, Krogan NJ, Beltrao P. Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes. Plos Computational Biology. 11: e1004362. PMID 26312481 DOI: 10.1371/journal.pcbi.1004362  0.56
2015 Shah PS, Wojcechowskyj JA, Eckhardt M, Krogan NJ. Comparative mapping of host-pathogen protein-protein interactions. Current Opinion in Microbiology. 27: 62-68. PMID 26275922 DOI: 10.1016/j.mib.2015.07.008  0.72
2015 Mark KG, Meza-Gutierrez F, Johnson JR, Newton BW, Krogan NJ, Toczyski DP. Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1. Biochemistry. 54: 4423-6. PMID 26161950 DOI: 10.1021/acs.biochem.5b00504  0.72
2015 Mirrashidi KM, Elwell CA, Verschueren E, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, Jäger S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, ... ... Krogan NJ, et al. Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. Cell Host & Microbe. PMID 26118995 DOI: 10.1016/j.chom.2015.06.004  0.72
2015 Krogan NJ, Lippman S, Agard DA, Ashworth A, Ideker T. The Cancer Cell Map Initiative: Defining the Hallmark Networks of Cancer. Molecular Cell. 58: 690-698. PMID 26000852 DOI: 10.1016/j.molcel.2015.05.008  0.72
2015 Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, ... ... Krogan NJ, et al. Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Reports. 11: 1236-50. PMID 25981045 DOI: 10.1016/j.celrep.2015.04.038  0.72
2015 Jessulat M, Malty RH, Nguyen-Tran DH, Deineko V, Aoki H, Vlasblom J, Omidi K, Jin K, Minic Z, Hooshyar M, Burnside D, Samanfar B, Phanse S, Freywald T, Prasad B, ... ... Krogan NJ, et al. Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining. Molecular and Cellular Biology. 35: 2448-63. PMID 25963654 DOI: 10.1128/MCB.00007-15  0.72
2015 Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ. Differential genetic interactions of yeast stress response MAPK pathways. Molecular Systems Biology. 11: 800. PMID 25888283  0.56
2015 Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/eLife.07314  0.32
2015 Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, ... ... Krogan NJ, et al. NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer. Cell Reports. 11: 98-110. PMID 25843712 DOI: 10.1016/j.celrep.2015.03.012  0.72
2015 Patrick KL, Ryan CJ, Xu J, Lipp JJ, Nissen KE, Roguev A, Shales M, Krogan NJ, Guthrie C. Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast. Plos Genetics. 11: e1005074. PMID 25825871 DOI: 10.1371/journal.pgen.1005074  0.72
2015 Sánchez A, Roguev A, Krogan NJ, Russell P. Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants. G3 (Bethesda, Md.). 5: 953-62. PMID 25795664 DOI: 10.1534/g3.115.017251  0.72
2015 DePaula-Silva AB, Cassiday PA, Chumley J, Bosque A, Monteiro-Filho CM, Mahon CS, Cone KR, Krogan N, Elde NC, Planelles V. Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr. Virology. 477: 10-7. PMID 25618414 DOI: 10.1016/j.virol.2014.12.040  0.72
2015 Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M. A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. Molecular Cell. 57: 329-40. PMID 25616068 DOI: 10.1016/j.molcel.2014.12.028  0.72
2015 Davis ZH, Verschueren E, Jang GM, Kleffman K, Johnson JR, Park J, Von Dollen J, Maher MC, Johnson T, Newton W, Jäger S, Shales M, Horner J, Hernandez RD, Krogan NJ, et al. Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. Molecular Cell. 57: 349-60. PMID 25544563 DOI: 10.1016/j.molcel.2014.11.026  0.72
2015 Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, ... ... Krogan NJ, et al. Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map. Cancer Discovery. 5: 154-67. PMID 25501949 DOI: 10.1158/2159-8290.CD-14-0552  0.44
2015 Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM. Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Molecular and Cellular Biology. 35: 468-78. PMID 25384976 DOI: 10.1128/MCB.01157-14  0.72
2015 Downey M, Johnson JR, Davey NE, Newton BW, Johnson TL, Galaang S, Seller CA, Krogan N, Toczyski DP. Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1. Molecular & Cellular Proteomics : McP. 14: 162-76. PMID 25381059 DOI: 10.1074/mcp.M114.043141  0.72
2015 Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ. Differential genetic interactions of yeast stress response MAPK pathways Molecular Systems Biology. 11: 1-13. DOI: 10.15252/msb.20145606  0.72
2014 Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT. Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes & Development. 28: 2547-63. PMID 25403183 DOI: 10.1101/gad.249425.114  0.72
2014 Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W. Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. Genome Medicine. 6: 68. PMID 25302077 DOI: 10.1186/s13073-014-0068-4  0.72
2014 Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ. Quantitative analysis of triple-mutant genetic interactions. Nature Protocols. 9: 1867-81. PMID 25010907 DOI: 10.1038/nprot.2014.127  0.72
2014 Anver S, Roguev A, Zofall M, Krogan NJ, Grewal SI, Harmer SL. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Embo Reports. 15: 894-902. PMID 24957674 DOI: 10.15252/embr.201438902  0.72
2014 Braberg H, Moehle EA, Shales M, Guthrie C, Krogan NJ. Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 706-13. PMID 24842270 DOI: 10.1002/bies.201400044  0.72
2014 Moehle EA, Braberg H, Krogan NJ, Guthrie C. Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate. Rna Biology. 11: 313-9. PMID 24717535 DOI: 10.4161/rna.28646  0.72
2014 Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, et al. Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. Cell Reports. 6: 892-905. PMID 24565511 DOI: 10.1016/j.celrep.2014.01.029  0.72
2014 Kriegenburg F, Jakopec V, Poulsen EG, Nielsen SV, Roguev A, Krogan N, Gordon C, Fleig U, Hartmann-Petersen R. A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability Plos Genetics. 10. PMID 24497846 DOI: 10.1371/journal.pgen.1004140  0.72
2014 Martín GM, King DA, Green EM, Garcia-Nieto PE, Alexander R, Collins SR, Krogan NJ, Gozani OP, Morrison AJ. Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons. Epigenetics : Official Journal of the Dna Methylation Society. 9: 513-22. PMID 24442241 DOI: 10.4161/epi.27645  0.72
2014 Kabeche R, Roguev A, Krogan NJ, Moseley JB. A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation. Journal of Cell Science. 127: 1318-26. PMID 24434583 DOI: 10.1242/jcs.143545  0.72
2014 Lu H, Li Z, Xue Y, Schulze-Gahmen U, Johnson JR, Krogan NJ, Alber T, Zhou Q. AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation. Proceedings of the National Academy of Sciences of the United States of America. 111: E15-24. PMID 24367103 DOI: 10.1073/pnas.1318503111  0.72
2014 Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science (New York, N.Y.). 343: 428-32. PMID 24356113 DOI: 10.1126/science.1243640  0.72
2013 Beltrao P, Bork P, Krogan NJ, van Noort V. Evolution and functional cross-talk of protein post-translational modifications. Molecular Systems Biology. 9: 714. PMID 24366814 DOI: 10.1002/msb.201304521  0.72
2013 Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae. Cell Reports. 5: 1725-36. PMID 24360963 DOI: 10.1016/j.celrep.2013.11.040  0.44
2013 Ryan CJ, Cimerman?i? P, Szpiech ZA, Sali A, Hernandez RD, Krogan NJ. High-resolution network biology: connecting sequence with function. Nature Reviews. Genetics. 14: 865-79. PMID 24197012 DOI: 10.1038/nrg3574  0.72
2013 Millán-Zambrano G, Rodríguez-Gil A, Peñate X, de Miguel-Jiménez L, Morillo-Huesca M, Krogan N, Chávez S. The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation Plos Genetics. 9. PMID 24068951 DOI: 10.1371/journal.pgen.1003776  0.72
2013 Aristizabal MJ, Negri GL, Benschop JJ, Holstege FC, Krogan NJ, Kobor MS. High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. Plos Genetics. 9: e1003758. PMID 24009531 DOI: 10.1371/journal.pgen.1003758  0.72
2013 Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, ... ... Krogan NJ, et al. From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. Cell. 154: 775-88. PMID 23932120 DOI: 10.1016/j.cell.2013.07.033  0.72
2013 Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R, Simons K, Krogan NJ, Ernst R. A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Molecular Cell. 51: 519-30. PMID 23891562 DOI: 10.1016/j.molcel.2013.06.014  0.44
2013 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods. 10: 676-82. PMID 23749301 DOI: 10.1038/nmeth.2519  0.72
2013 Haber JE, Braberg H, Wu Q, Alexander R, Haase J, Ryan C, Lipkin-Moore Z, Franks-Skiba KE, Johnson T, Shales M, Lenstra TL, Holstege FC, Johnson JR, Bloom K, Krogan NJ. Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation. Cell Reports. 3: 2168-78. PMID 23746449 DOI: 10.1016/j.celrep.2013.05.007  0.72
2013 Bushman FD, Barton S, Bailey A, Greig C, Malani N, Bandyopadhyay S, Young J, Chanda S, Krogan N. Bringing it all together: big data and HIV research. Aids (London, England). 27: 835-8. PMID 23719353 DOI: 10.1097/QAD.0b013e32835cb785  0.72
2013 Ryan CJ, Krogan NJ, Cunningham P, Cagney G. All or nothing: protein complexes flip essentiality between distantly related eukaryotes. Genome Biology and Evolution. 5: 1049-59. PMID 23661563 DOI: 10.1093/gbe/evt074  0.72
2013 Schulze-Gahmen U, Upton H, Birnberg A, Bao K, Chou S, Krogan NJ, Zhou Q, Alber T. The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. Elife. 2: e00327. PMID 23471103 DOI: 10.7554/eLife.00327  0.72
2013 Roguev A, Talbot D, Negri GL, Shales M, Cagney G, Bandyopadhyay S, Panning B, Krogan NJ. Quantitative genetic-interaction mapping in mammalian cells. Nature Methods. 10: 432-7. PMID 23407553 DOI: 10.1038/nmeth.2398  0.72
2013 Fraser JS, Gross JD, Krogan NJ. From systems to structure: bridging networks and mechanism. Molecular Cell. 49: 222-31. PMID 23352243 DOI: 10.1016/j.molcel.2013.01.003  0.72
2013 Kim DY, Kwon E, Hartley PD, Crosby DC, Mann S, Krogan NJ, Gross JD. CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Molecular Cell. 49: 632-44. PMID 23333304 DOI: 10.1016/j.molcel.2012.12.012  0.72
2013 Albin JS, Anderson JS, Johnson JR, Harjes E, Matsuo H, Krogan NJ, Harris RS. Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. Journal of Molecular Biology. 425: 1172-82. PMID 23318957 DOI: 10.1016/j.jmb.2013.01.010  0.72
2013 Guénolé A, Srivas R, Vreeken K, Wang ZZ, Wang S, Krogan NJ, Ideker T, van Attikum H. Dissection of DNA damage responses using multiconditional genetic interaction maps. Molecular Cell. 49: 346-58. PMID 23273983 DOI: 10.1016/j.molcel.2012.11.023  0.72
2013 Chou S, Upton H, Bao K, Schulze-Gahmen U, Samelson AJ, He N, Nowak A, Lu H, Krogan NJ, Zhou Q, Alber T. HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold. Proceedings of the National Academy of Sciences of the United States of America. 110: E123-31. PMID 23251033 DOI: 10.1073/pnas.1216971110  0.72
2013 Dutkowski J, Kramer M, Surma MA, Balakrishnan R, Cherry JM, Krogan NJ, Ideker T. A gene ontology inferred from molecular networks. Nature Biotechnology. 31: 38-45. PMID 23242164 DOI: 10.1038/nbt.2463  0.72
2012 Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, Hayashi F, Yokoyama S, Krogan NJ, Harris RS, Peterlin BM, et al. Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G. Plos Pathogens. 8: e1003085. PMID 23300442 DOI: 10.1371/journal.ppat.1003085  0.72
2012 Moehle EA, Ryan CJ, Krogan NJ, Kress TL, Guthrie C. The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. Plos Genetics. 8: e1003101. PMID 23209445 DOI: 10.1371/journal.pgen.1003101  0.72
2012 Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/ng.2434  0.72
2012 Sánchez A, Sharma S, Rozenzhak S, Roguev A, Krogan NJ, Chabes A, Russell P. Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant. Molecular and Cellular Biology. 32: 4445-54. PMID 22927644 DOI: 10.1128/MCB.01062-12  0.72
2012 Beltrao P, Ryan C, Krogan NJ. Comparative interaction networks: bridging genotype to phenotype. Advances in Experimental Medicine and Biology. 751: 139-56. PMID 22821457 DOI: 10.1007/978-1-4614-3567-9_7  0.72
2012 Beltrao P, Albanèse V, Kenner LR, Swaney DL, Burlingame A, Villén J, Lim WA, Fraser JS, Frydman J, Krogan NJ. Systematic functional prioritization of protein posttranslational modifications. Cell. 150: 413-25. PMID 22817900 DOI: 10.1016/j.cell.2012.05.036  0.72
2012 Lu C, Luo Z, Jäger S, Krogan NJ, Peterlin BM. Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles. Journal of Virology. 86: 10517-23. PMID 22811528 DOI: 10.1128/JVI.00868-12  0.72
2012 Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, ... ... Krogan NJ, et al. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell. 46: 691-704. PMID 22681890 DOI: 10.1016/j.molcel.2012.05.028  0.72
2012 Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF. Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. Plos Genetics. 8: e1002576. PMID 22438827 DOI: 10.1371/journal.pgen.1002576  0.72
2012 Ideker T, Krogan NJ. Differential network biology. Molecular Systems Biology. 8: 565. PMID 22252388 DOI: 10.1038/msb.2011.99  0.72
2012 Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, ... ... Krogan NJ, et al. Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature. 481: 371-5. PMID 22190037 DOI: 10.1038/nature10693  0.72
2012 Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, ... ... Krogan NJ, et al. Global landscape of HIV-human protein complexes. Nature. 481: 365-70. PMID 22190034 DOI: 10.1038/nature10719  0.72
2012 Li M, Shandilya SM, Carpenter MA, Rathore A, Brown WL, Perkins AL, Harki DA, Solberg J, Hook DJ, Pandey KK, Parniak MA, Johnson JR, Krogan NJ, Somasundaran M, Ali A, et al. First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. Acs Chemical Biology. 7: 506-17. PMID 22181350 DOI: 10.1021/cb200440y  0.72
2012 Naji S, Ambrus G, Cimerman?i? P, Reyes JR, Johnson JR, Filbrandt R, Huber MD, Vesely P, Krogan NJ, Yates JR, Saphire AC, Gerace L. Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production. Molecular & Cellular Proteomics : McP. 11: M111.015313. PMID 22174317 DOI: 10.1074/mcp.M111.015313  0.72
2012 Fuchs SM, Kizer KO, Braberg H, Krogan NJ, Strahl BD. RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36. The Journal of Biological Chemistry. 287: 3249-56. PMID 22157004 DOI: 10.1074/jbc.M111.273953  0.72
2011 Karotki L, Huiskonen JT, Stefan CJ, Ziółkowska NE, Roth R, Surma MA, Krogan NJ, Emr SD, Heuser J, Grünewald K, Walther TC. Eisosome proteins assemble into a membrane scaffold. The Journal of Cell Biology. 195: 889-902. PMID 22123866 DOI: 10.1083/jcb.201104040  0.72
2011 Ryan C, Cagney G, Krogan N, Cunningham P, Greene D. Imputing and predicting quantitative genetic interactions in epistatic MAPs. Methods in Molecular Biology (Clifton, N.J.). 781: 353-61. PMID 21877290 DOI: 10.1007/978-1-61779-276-2_17  0.72
2011 Wang AY, Aristizabal MJ, Ryan C, Krogan NJ, Kobor MS. Key functional regions in the histone variant H2A.Z C-terminal docking domain. Molecular and Cellular Biology. 31: 3871-84. PMID 21791612 DOI: 10.1128/MCB.05182-11  0.72
2011 Fahey ME, Bennett MJ, Mahon C, Jäger S, Pache L, Kumar D, Shapiro A, Rao K, Chanda SK, Craik CS, Frankel AD, Krogan NJ. GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data. Bmc Bioinformatics. 12: 298. PMID 21777475 DOI: 10.1186/1471-2105-12-298  0.72
2011 Charles GM, Chen C, Shih SC, Collins SR, Beltrao P, Zhang X, Sharma T, Tan S, Burlingame AL, Krogan NJ, Madhani HD, Narlikar GJ. Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress. Proceedings of the National Academy of Sciences of the United States of America. 108: 10620-5. PMID 21673141 DOI: 10.1073/pnas.1019735108  0.72
2011 Ryan C, Greene D, Guénolé A, van Attikum H, Krogan NJ, Cunningham P, Cagney G. Improved functional overview of protein complexes using inferred epistatic relationships. Bmc Systems Biology. 5: 80. PMID 21605386 DOI: 10.1186/1752-0509-5-80  0.72
2011 Temkin P, Lauffer B, Jäger S, Cimermancic P, Krogan NJ, von Zastrow M. SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Nature Cell Biology. 13: 715-21. PMID 21602791 DOI: 10.1038/ncb2252  0.72
2011 Stewart EV, Nwosu CC, Tong Z, Roguev A, Cummins TD, Kim DU, Hayles J, Park HO, Hoe KL, Powell DW, Krogan NJ, Espenshade PJ. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Molecular Cell. 42: 160-71. PMID 21504829 DOI: 10.1016/j.molcel.2011.02.035  0.72
2011 Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak KM, Lee KJ, Wong A, Shales M, Lovett S, Winkler ME, Krogan NJ, Typas A, et al. Phenotypic landscape of a bacterial cell. Cell. 144: 143-56. PMID 21185072 DOI: 10.1016/j.cell.2010.11.052  0.72
2011 Jäger S, Gulbahce N, Cimermancic P, Kane J, He N, Chou S, D'Orso I, Fernandes J, Jang G, Frankel AD, Alber T, Zhou Q, Krogan NJ. Purification and characterization of HIV-human protein complexes. Methods (San Diego, Calif.). 53: 13-9. PMID 20708689 DOI: 10.1016/j.ymeth.2010.08.007  0.72
2011 Casey F, Krogan N, Shields DC, Cagney G. Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs Bmc Systems Biology. 5. DOI: 10.1186/1752-0509-5-133  0.72
2010 Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, Babu MM, Elledge SJ, Toczyski D, Lokey RS, Krogan NJ. Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Molecular Systems Biology. 6: 451. PMID 21179023 DOI: 10.1038/msb.2010.107  0.72
2010 van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, ... ... Krogan NJ, et al. Functional overlap and regulatory links shape genetic interactions between signaling pathways. Cell. 143: 991-1004. PMID 21145464 DOI: 10.1016/j.cell.2010.11.021  0.32
2010 Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, ... ... Krogan NJ, et al. Rewiring of genetic networks in response to DNA damage. Science (New York, N.Y.). 330: 1385-9. PMID 21127252 DOI: 10.1126/science.1195618  0.72
2010 Zheng J, Benschop JJ, Shales M, Kemmeren P, Greenblatt J, Cagney G, Holstege F, Li H, Krogan NJ. Epistatic relationships reveal the functional organization of yeast transcription factors. Molecular Systems Biology. 6: 420. PMID 20959818 DOI: 10.1038/msb.2010.77  0.72
2010 Mehta M, Braberg H, Wang S, Lozsa A, Shales M, Solache A, Krogan NJ, Keogh MC. Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated. The Journal of Biological Chemistry. 285: 39855-65. PMID 20952395 DOI: 10.1074/jbc.M110.185967  0.72
2010 Collins SR, Roguev A, Krogan NJ. Quantitative genetic interaction mapping using the E-MAP approach. Methods in Enzymology. 470: 205-31. PMID 20946812 DOI: 10.1016/S0076-6879(10)70009-4  0.72
2010 Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, et al. A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers. Molecular Systems Biology. 6: 377. PMID 20531406 DOI: 10.1038/msb.2010.31  0.72
2010 Aguilar PS, Fröhlich F, Rehman M, Shales M, Ulitsky I, Olivera-Couto A, Braberg H, Shamir R, Walter P, Mann M, Ejsing CS, Krogan NJ, Walther TC. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nature Structural & Molecular Biology. 17: 901-8. PMID 20526336 DOI: 10.1038/nsmb.1829  0.72
2010 Beltrao P, Cagney G, Krogan NJ. Quantitative genetic interactions reveal biological modularity. Cell. 141: 739-45. PMID 20510918 DOI: 10.1016/j.cell.2010.05.019  0.72
2010 He N, Liu M, Hsu J, Xue Y, Chou S, Burlingame A, Krogan NJ, Alber T, Zhou Q. HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Molecular Cell. 38: 428-38. PMID 20471948 DOI: 10.1016/j.molcel.2010.04.013  0.72
2010 Fischbach MA, Krogan NJ. The next frontier of systems biology: higher-order and interspecies interactions. Genome Biology. 11: 208. PMID 20441613 DOI: 10.1186/gb-2010-11-5-208  0.72
2010 Walker E, Chang WY, Hunkapiller J, Cagney G, Garcha K, Torchia J, Krogan NJ, Reiter JF, Stanford WL. Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell. 6: 153-66. PMID 20144788 DOI: 10.1016/j.stem.2009.12.014  0.72
2010 Lenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, Krogan NJ, Plemenitas A, Peterlin BM. HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Traffic (Copenhagen, Denmark). 11: 110-22. PMID 19912576 DOI: 10.1111/j.1600-0854.2009.01006.x  0.72
2009 Hannum G, Srivas R, Guénolé A, van Attikum H, Krogan NJ, Karp RM, Ideker T. Genome-wide association data reveal a global map of genetic interactions among protein complexes. Plos Genetics. 5: e1000782. PMID 20041197 DOI: 10.1371/journal.pgen.1000782  0.72
2009 Ulitsky I, Krogan NJ, Shamir R. Towards accurate imputation of quantitative genetic interactions. Genome Biology. 10: R140. PMID 20003301 DOI: 10.1186/gb-2009-10-12-r140  0.72
2009 Collins SR, Weissman JS, Krogan NJ. From information to knowledge: new technologies for defining gene function. Nature Methods. 6: 721-23. PMID 19953683 DOI: 10.1038/nmeth1009-721  0.72
2009 Kim HS, Vanoosthuyse V, Fillingham J, Roguev A, Watt S, Kislinger T, Treyer A, Carpenter LR, Bennett CS, Emili A, Greenblatt JF, Hardwick KG, Krogan NJ, Bähler J, Keogh MC. An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe. Nature Structural & Molecular Biology. 16: 1286-93. PMID 19915592 DOI: 10.1038/nsmb.1688  0.72
2009 Khanna M, Van Bakel H, Tang X, Calarco JA, Babak T, Guo G, Emili A, Greenblatt JF, Hughes TR, Krogan NJ, Blencowe BJ. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. Rna (New York, N.Y.). 15: 2174-85. PMID 19789211 DOI: 10.1261/rna.1790509  0.72
2009 Beltrao P, Trinidad JC, Fiedler D, Roguev A, Lim WA, Shokat KM, Burlingame AL, Krogan NJ. Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. Plos Biology. 7: e1000134. PMID 19547744 DOI: 10.1371/journal.pbio.1000134  0.6
2009 Babu M, Krogan NJ, Awrey DE, Emili A, Greenblatt JF. Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 548: 187-207. PMID 19521826 DOI: 10.1007/978-1-59745-540-4_11  0.72
2009 Bushman FD, Malani N, Fernandes J, D'Orso I, Cagney G, Diamond TL, Zhou H, Hazuda DJ, Espeseth AS, König R, Bandyopadhyay S, Ideker T, Goff SP, Krogan NJ, Frankel AD, et al. Host cell factors in HIV replication: meta-analysis of genome-wide studies. Plos Pathogens. 5: e1000437. PMID 19478882 DOI: 10.1371/journal.ppat.1000437  0.72
2009 Selth LA, Lorch Y, Ocampo-Hafalla MT, Mitter R, Shales M, Krogan NJ, Kornberg RD, Svejstrup JQ. An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics. Molecular and Cellular Biology. 29: 4220-34. PMID 19470761 DOI: 10.1128/MCB.01882-08  0.72
2009 Wiseman RL, Chin KT, Haynes CM, Stanhill A, Xu CF, Roguev A, Krogan NJ, Neubert TA, Ron D. Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle. The Journal of Biological Chemistry. 284: 15233-45. PMID 19349280 DOI: 10.1074/jbc.M109.002121  0.72
2009 Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, ... ... Krogan NJ, et al. Functional organization of the S. cerevisiae phosphorylation network. Cell. 136: 952-63. PMID 19269370 DOI: 10.1016/j.cell.2008.12.039  0.72
2009 Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, Pe'er D, Koller D. Learning a prior on regulatory potential from eQTL data. Plos Genetics. 5: e1000358. PMID 19180192 DOI: 10.1371/journal.pgen.1000358  0.72
2009 Wang H, Kakaradov B, Collins SR, Karotki L, Fiedler D, Shales M, Shokat KM, Walther TC, Krogan NJ, Koller D. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Molecular & Cellular Proteomics : McP. 8: 1361-81. PMID 19176519 DOI: 10.1074/mcp.M800490-MCP200  0.44
2008 Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. High-throughput, quantitative analyses of genetic interactions in E. coli. Nature Methods. 5: 781-7. PMID 19160513 DOI: 10.1038/nmeth.1240  0.72
2008 Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Molecular Cell. 32: 735-46. PMID 19061648 DOI: 10.1016/j.molcel.2008.11.012  0.72
2008 Kress TL, Krogan NJ, Guthrie C. A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. Molecular Cell. 32: 727-34. PMID 19061647 DOI: 10.1016/j.molcel.2008.11.013  0.72
2008 Shevchenko A, Roguev A, Schaft D, Buchanan L, Habermann B, Sakalar C, Thomas H, Krogan NJ, Shevchenko A, Stewart AF. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biology. 9: R167. PMID 19040720 DOI: 10.1186/gb-2008-9-11-r167  0.72
2008 Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/science.1162790  0.72
2008 Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, ... Krogan NJ, et al. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science (New York, N.Y.). 322: 405-10. PMID 18818364 DOI: 10.1126/science.1162609  0.72
2008 Casey FP, Cagney G, Krogan NJ, Shields DC. Optimal stepwise experimental design for pairwise functional interaction studies. Bioinformatics (Oxford, England). 24: 2733-9. PMID 18805797 DOI: 10.1093/bioinformatics/btn472  0.72
2008 Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nature Methods. 5: 711-8. PMID 18622397 DOI: 10.1038/nmeth.1234  0.72
2008 Fillingham J, Recht J, Silva AC, Suter B, Emili A, Stagljar I, Krogan NJ, Allis CD, Keogh MC, Greenblatt JF. Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Molecular and Cellular Biology. 28: 4342-53. PMID 18458063 DOI: 10.1128/MCB.00182-08  0.72
2008 Roguev A, Krogan NJ. BAC to the future: functional genomics in mammals. Nature Methods. 5: 383-4. PMID 18446155 DOI: 10.1038/nmeth0508-383  0.72
2008 Bandyopadhyay S, Kelley R, Krogan NJ, Ideker T. Functional maps of protein complexes from quantitative genetic interaction data. Plos Computational Biology. 4: e1000065. PMID 18421374 DOI: 10.1371/journal.pcbi.1000065  0.72
2007 Roguev A, Wiren M, Weissman JS, Krogan NJ. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nature Methods. 4: 861-6. PMID 17893680 DOI: 10.1038/nmeth1098  0.72
2007 Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 130: 499-511. PMID 17693258 DOI: 10.1016/j.cell.2007.06.010  0.72
2007 Zaharik ML, Lamb SS, Baker KE, Krogan NJ, Neuhard J, Kelln RA. Mutations in yhiT enable utilization of exogenous pyrimidine intermediates in Salmonella enterica serovar Typhimurium. Microbiology (Reading, England). 153: 2472-82. PMID 17660412 DOI: 10.1099/mic.0.2007/007583-0  0.72
2007 Wyce A, Xiao T, Whelan KA, Kosman C, Walter W, Eick D, Hughes TR, Krogan NJ, Strahl BD, Berger SL. H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Molecular Cell. 27: 275-88. PMID 17643376 DOI: 10.1016/j.molcel.2007.01.035  0.72
2007 Gupta R, Kus B, Fladd C, Wasmuth J, Tonikian R, Sidhu S, Krogan NJ, Parkinson J, Rotin D. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Molecular Systems Biology. 3: 116. PMID 17551511 DOI: 10.1038/msb4100159  0.72
2007 Roguev A, Krogan NJ. SIN-fully silent: HDAC complexes in fission yeast. Nature Structural & Molecular Biology. 14: 358-9. PMID 17473877 DOI: 10.1038/nsmb0507-358  0.72
2007 Ihmels J, Collins SR, Schuldiner M, Krogan NJ, Weissman JS. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Molecular Systems Biology. 3: 86. PMID 17389874 DOI: 10.1038/msb4100127  0.72
2007 Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5836-41. PMID 17389396 DOI: 10.1073/pnas.0607996104  0.72
2007 Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Krogan NJ, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/nature05649  0.72
2007 Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 6: 439-50. PMID 17200106 DOI: 10.1074/mcp.M600381-MCP200  0.72
2007 Xiao T, Shibata Y, Rao B, Laribee RN, O'Rourke R, Buck MJ, Greenblatt JF, Krogan NJ, Lieb JD, Strahl BD. The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes. Molecular and Cellular Biology. 27: 721-31. PMID 17088384 DOI: 10.1128/MCB.01628-06  0.72
2007 Butland G, Krogan NJ, Xu J, Yang WH, Aoki H, Li JS, Krogan N, Menendez J, Cagney G, Kiani GC, Jessulat MG, Datta N, Ivanov I, Abouhaidar MG, Emili A, et al. Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs. Journal of Cellular Biochemistry. 100: 642-52. PMID 16983699 DOI: 10.1002/jcb.21016  0.4
2006 Schuldiner M, Collins SR, Weissman JS, Krogan NJ. Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods (San Diego, Calif.). 40: 344-52. PMID 17101447 DOI: 10.1016/j.ymeth.2006.07.034  0.72
2006 Cagney G, Alvaro D, Reid RJ, Thorpe PH, Rothstein R, Krogan NJ. Functional genomics of the yeast DNA-damage response. Genome Biology. 7: 233. PMID 16959047 DOI: 10.1186/gb-2006-7-9-233  0.72
2006 Fillingham J, Keogh MC, Krogan NJ. GammaH2AX and its role in DNA double-strand break repair. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 568-77. PMID 16936829 DOI: 10.1139/o06-072  0.72
2006 Collins SR, Schuldiner M, Krogan NJ, Weissman JS. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biology. 7: R63. PMID 16859555 DOI: 10.1186/gb-2006-7-7-r63  0.72
2006 Maciag K, Altschuler SJ, Slack MD, Krogan NJ, Emili A, Greenblatt JF, Maniatis T, Wu LF. Systems-level analyses identify extensive coupling among gene expression machines. Molecular Systems Biology. 2: 2006.0003. PMID 16738550 DOI: 10.1038/msb4100045  0.72
2006 Krogan NJ, Hughes TR. Signals and systems. Genome Biology. 7: 313. PMID 16677414 DOI: 10.1186/gb-2006-7-4-313  0.72
2006 Downey M, Houlsworth R, Maringele L, Rollie A, Brehme M, Galicia S, Guillard S, Partington M, Zubko MK, Krogan NJ, Emili A, Greenblatt JF, Harrington L, Lydall D, Durocher D. A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell. 124: 1155-68. PMID 16564010 DOI: 10.1016/j.cell.2005.12.044  0.72
2006 Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/nature04670  0.72
2006 Keogh MC, Mennella TA, Sawa C, Berthelet S, Krogan NJ, Wolek A, Podolny V, Carpenter LR, Greenblatt JF, Baetz K, Buratowski S. The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4. Genes & Development. 20: 660-5. PMID 16543219 DOI: 10.1101/gad.1388106  0.72
2006 Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, ... ... Krogan NJ, et al. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature. 439: 497-501. PMID 16299494 DOI: 10.1038/nature04384  0.72
2005 Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, ... ... Krogan NJ, et al. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 123: 593-605. PMID 16286008 DOI: 10.1016/j.cell.2005.10.025  0.72
2005 Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 123: 507-19. PMID 16269340 DOI: 10.1016/j.cell.2005.08.031  0.72
2005 Prather D, Krogan NJ, Emili A, Greenblatt JF, Winston F. Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae. Molecular and Cellular Biology. 25: 10122-35. PMID 16260625 DOI: 10.1128/MCB.25.22.10122-10135.2005  0.72
2005 Laribee RN, Krogan NJ, Xiao T, Shibata Y, Hughes TR, Greenblatt JF, Strahl BD. BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Current Biology : Cb. 15: 1487-93. PMID 16040246 DOI: 10.1016/j.cub.2005.07.028  0.72
2005 Emre NC, Ingvarsdottir K, Wyce A, Wood A, Krogan NJ, Henry KW, Li K, Marmorstein R, Greenblatt JF, Shilatifard A, Berger SL. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Molecular Cell. 17: 585-94. PMID 15721261 DOI: 10.1016/j.molcel.2005.01.007  0.72
2005 Ingvarsdottir K, Krogan NJ, Emre NC, Wyce A, Thompson NJ, Emili A, Hughes TR, Greenblatt JF, Berger SL. H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Molecular and Cellular Biology. 25: 1162-72. PMID 15657441 DOI: 10.1128/MCB.25.3.1162-1172.2005  0.72
2005 Xiao T, Kao CF, Krogan NJ, Sun ZW, Greenblatt JF, Osley MA, Strahl BD. Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Molecular and Cellular Biology. 25: 637-51. PMID 15632065 DOI: 10.1128/MCB.25.2.637-651.2005  0.72
2005 Kong SE, Kobor MS, Krogan NJ, Somesh BP, Søgaard TM, Greenblatt JF, Svejstrup JQ. Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator. The Journal of Biological Chemistry. 280: 4299-306. PMID 15563457 DOI: 10.1074/jbc.M411071200  0.72
2005 Emre, Berger, Ingvarsdottir K, Wyce A, Henry K, Li K, Marmorstein R, Wood A, Shilatifard A, Krogan NJ, Greenblatt JF. Link between histone deubiquitination and protection of telomeres Cancer Biology and Therapy. 4: 11DUMMY.  0.72
2004 Krogan NJ, Lam MH, Fillingham J, Keogh MC, Gebbia M, Li J, Datta N, Cagney G, Buratowski S, Emili A, Greenblatt JF. Proteasome involvement in the repair of DNA double-strand breaks. Molecular Cell. 16: 1027-34. PMID 15610744 DOI: 10.1016/j.molcel.2004.11.033  0.72
2004 Morrison AJ, Highland J, Krogan NJ, Arbel-Eden A, Greenblatt JF, Haber JE, Shen X. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell. 119: 767-75. PMID 15607974 DOI: 10.1016/j.cell.2004.11.037  0.72
2004 Kim M, Krogan NJ, Vasiljeva L, Rando OJ, Nedea E, Greenblatt JF, Buratowski S. The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II. Nature. 432: 517-22. PMID 15565157 DOI: 10.1038/nature03041  0.72
2004 Krogan NJ, Baetz K, Keogh MC, Datta N, Sawa C, Kwok TC, Thompson NJ, Davey MG, Pootoolal J, Hughes TR, Emili A, Buratowski S, Hieter P, Greenblatt JF. Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proceedings of the National Academy of Sciences of the United States of America. 101: 13513-8. PMID 15353583 DOI: 10.1073/pnas.0405753101  0.72
2004 Mnaimneh S, Davierwala AP, Haynes J, Moffat J, Peng WT, Zhang W, Yang X, Pootoolal J, Chua G, Lopez A, Trochesset M, Morse D, Krogan NJ, Hiley SL, Li Z, et al. Exploration of essential gene functions via titratable promoter alleles. Cell. 118: 31-44. PMID 15242642 DOI: 10.1016/j.cell.2004.06.013  0.72
2004 Peng WT, Krogan NJ, Richards DP, Greenblatt JF, Hughes TR. ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae. Nucleic Acids Research. 32: 1993-9. PMID 15056729 DOI: 10.1093/nar/gkh518  0.72
2004 Golshani A, Krogan NJ, Xu J, Pacal M, Yang XC, Ivanov I, Providenti MA, Ganoza MC, Ivanov IG, AbouHaidar MG. Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA. Biochemical and Biophysical Research Communications. 316: 978-83. PMID 15044080 DOI: 10.1016/j.bbrc.2004.02.169  0.72
2004 Krogan NJ, Peng WT, Cagney G, Robinson MD, Haw R, Zhong G, Guo X, Zhang X, Canadien V, Richards DP, Beattie BK, Lalev A, Zhang W, Davierwala AP, Mnaimneh S, et al. High-definition macromolecular composition of yeast RNA-processing complexes. Molecular Cell. 13: 225-39. PMID 14759368 DOI: 10.1016/S1097-2765(04)00003-6  0.72
2004 Kim M, Ahn SH, Krogan NJ, Greenblatt JF, Buratowski S. Transitions in RNA polymerase II elongation complexes at the 3' ends of genes. The Embo Journal. 23: 354-64. PMID 14739930 DOI: 10.1038/sj.emboj.7600053  0.72
2004 Baetz KK, Krogan NJ, Emili A, Greenblatt J, Hieter P. The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Molecular and Cellular Biology. 24: 1232-44. PMID 14729968 DOI: 10.1128/MCB.24.3.1232-1244.2003  0.72
2003 Krogan NJ, Keogh MC, Datta N, Sawa C, Ryan OW, Ding H, Haw RA, Pootoolal J, Tong A, Canadien V, Richards DP, Wu X, Emili A, Hughes TR, Buratowski S, et al. A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Molecular Cell. 12: 1565-76. PMID 14690608 DOI: 10.1016/S1097-2765(03)00497-0  0.72
2003 Jansen R, Yu H, Greenbaum D, Kluger Y, Krogan NJ, Chung S, Emili A, Snyder M, Greenblatt JF, Gerstein M. A Bayesian networks approach for predicting protein-protein interactions from genomic data. Science (New York, N.Y.). 302: 449-53. PMID 14564010 DOI: 10.1126/science.1087361  0.72
2003 Peng WT, Robinson MD, Mnaimneh S, Krogan NJ, Cagney G, Morris Q, Davierwala AP, Grigull J, Yang X, Zhang W, Mitsakakis N, Ryan OW, Datta N, Jojic V, Pal C, et al. A panoramic view of yeast noncoding RNA processing. Cell. 113: 919-33. PMID 12837249  0.68
2003 Krogan NJ, Kim M, Tong A, Golshani A, Cagney G, Canadien V, Richards DP, Beattie BK, Emili A, Boone C, Shilatifard A, Buratowski S, Greenblatt J. Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Molecular and Cellular Biology. 23: 4207-18. PMID 12773564 DOI: 10.1128/MCB.23.12.4207-4218.2003  0.72
2003 Krogan NJ, Dover J, Wood A, Schneider J, Heidt J, Boateng MA, Dean K, Ryan OW, Golshani A, Johnston M, Greenblatt JF, Shilatifard A. The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Molecular Cell. 11: 721-9. PMID 12667454 DOI: 10.1016/S1097-2765(03)00091-1  0.72
2003 Wood A, Krogan NJ, Dover J, Schneider J, Heidt J, Boateng MA, Dean K, Golshani A, Zhang Y, Greenblatt JF, Johnston M, Shilatifard A. Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Molecular Cell. 11: 267-74. PMID 12535539 DOI: 10.1016/S1097-2765(02)00802-X  0.72
2002 Krogan NJ, Kim M, Ahn SH, Zhong G, Kobor MS, Cagney G, Emili A, Shilatifard A, Buratowski S, Greenblatt JF. RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Molecular and Cellular Biology. 22: 6979-92. PMID 12242279 DOI: 10.1128/MCB.22.20.6979-6992.2002  0.72
2002 Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A. COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. The Journal of Biological Chemistry. 277: 10753-5. PMID 11805083 DOI: 10.1074/jbc.C200023200  0.72
2001 Krogan NJ, Greenblatt JF. Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae. Molecular and Cellular Biology. 21: 8203-12. PMID 11689709 DOI: 10.1128/MCB.21.23.8203-8212.2001  0.72
2001 Miller T, Krogan NJ, Dover J, Erdjument-Bromage H, Tempst P, Johnston M, Greenblatt JF, Shilatifard A. COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 12902-7. PMID 11687631 DOI: 10.1073/pnas.231473398  0.72
1998 Krogan NJ, Zaharik ML, Neuhard J, Kelln RA. A combination of three mutations, dcd, pyrH, and cdd, establishes thymidine (Deoxyuridine) auxotrophy in thyA+ strains of Salmonella typhimurium. Journal of Bacteriology. 180: 5891-5. PMID 9811646  0.72
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