Alan R. Lehmann - Publications

Affiliations: 
University of Sussex, Falmer, England, United Kingdom 
Area:
DNA repair

198 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cipolla L, Bertoletti F, Maffia A, Liang CC, Lehmann AR, Cohn MA, Sabbioneda S. UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity. Nucleic Acids Research. PMID 31586398 DOI: 10.1093/nar/gkz824  0.72
2017 Bertoletti F, Cea V, Liang CC, Lanati T, Maffia A, Avarello MDM, Cipolla L, Lehmann AR, Cohn MA, Sabbioneda S. Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. Nucleic Acids Research. 45: 9441-9454. PMID 28934491 DOI: 10.1093/nar/gkx619  0.72
2016 van der Crabben SN, Hennus MP, McGregor GA, Ritter DI, Nagamani SC, Wells OS, Harakalova M, Chinn IK, Alt A, Vondrova L, Hochstenbach R, van Montfrans JM, Terheggen-Lagro SW, van Lieshout S, van Roosmalen MJ, ... ... Lehmann AR, et al. Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. The Journal of Clinical Investigation. PMID 27427983 DOI: 10.1172/JCI82890  0.32
2016 Fassihi H, Sethi M, Fawcett H, Wing J, Chandler N, Mohammed S, Craythorne E, Morley AM, Lim R, Turner S, Henshaw T, Garrood I, Giunti P, Hedderly T, Abiona A, ... ... Lehmann AR, et al. Deep phenotyping of 89 xeroderma pigmentosum patients reveals unexpected heterogeneity dependent on the precise molecular defect. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884178 DOI: 10.1073/pnas.1519444113  0.32
2015 Sethi M, Haque S, Fawcett H, Wing JF, Chandler N, Mohammed S, Frayling IM, Norris PG, McGibbon D, Young AR, Sarkany RP, Lehmann AR, Fassihi H. A Distinct Genotype of XP Complementation group A: Surprisingly Mild Phenotype Highly Prevalent in Northern India/ Pakistan/ Afghanistan. The Journal of Investigative Dermatology. PMID 26743599 DOI: 10.1016/j.jid.2015.12.031  0.32
2015 Guo C, Nakazawa Y, Woodbine L, Björkman A, Shimada M, Fawcett H, Jia N, Ohyama K, Li TS, Nagayama Y, Mitsutake N, Pan-Hammarström Q, Gennery AR, Lehmann AR, Jeggo PA, et al. XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency. The Journal of Allergy and Clinical Immunology. PMID 26255102 DOI: 10.1016/j.jaci.2015.06.007  0.32
2015 Zlatanou A, Sabbioneda S, Miller ES, Greenwalt A, Aggathanggelou A, Maurice MM, Lehmann AR, Stankovic T, Reverdy C, Colland F, Vaziri C, Stewart GS. USP7 is essential for maintaining Rad18 stability and DNA damage tolerance. Oncogene. PMID 25961918 DOI: 10.1038/onc.2015.149  0.72
2015 Kozakova L, Vondrova L, Stejskal K, Charalabous P, Kolesar P, Lehmann AR, Uldrijan S, Sanderson CM, Zdrahal Z, Palecek JJ. The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex. Cell Cycle (Georgetown, Tex.). 14: 920-30. PMID 25590999 DOI: 10.1080/15384101.2014.1000112  0.32
2015 Lehmann AR. Xeroderma pigmentosum in the United kingdom. Photochemistry and Photobiology. 91: 484-5. PMID 24943090 DOI: 10.1111/php.12301  0.32
2014 Zheng CL, Wang NJ, Chung J, Moslehi H, Sanborn JZ, Hur JS, Collisson EA, Vemula SS, Naujokas A, Chiotti KE, Cheng JB, Fassihi H, Blumberg AJ, Bailey CV, Fudem GM, ... ... Lehmann AR, et al. Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes. Cell Reports. 9: 1228-34. PMID 25456125 DOI: 10.1016/j.celrep.2014.10.031  0.32
2014 Baple EL, Chambers H, Cross HE, Fawcett H, Nakazawa Y, Chioza BA, Harlalka GV, Mansour S, Sreekantan-Nair A, Patton MA, Muggenthaler M, Rich P, Wagner K, Coblentz R, Stein CK, ... ... Lehmann AR, et al. Hypomorphic PCNA mutation underlies a human DNA repair disorder. The Journal of Clinical Investigation. 124: 3137-46. PMID 24911150 DOI: 10.1172/JCI74593  0.32
2013 Sethi M, Lehmann AR, Fawcett H, Stefanini M, Jaspers N, Mullard K, Turner S, Robson A, McGibbon D, Sarkany R, Fassihi H. Patients with xeroderma pigmentosum complementation groups C, E and V do not have abnormal sunburn reactions. The British Journal of Dermatology. 169: 1279-87. PMID 23889214 DOI: 10.1111/bjd.12523  0.32
2013 Kashiyama K, Nakazawa Y, Pilz DT, Guo C, Shimada M, Sasaki K, Fawcett H, Wing JF, Lewin SO, Carr L, Li TS, Yoshiura K, Utani A, Hirano A, Yamashita S, ... ... Lehmann AR, et al. Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia. American Journal of Human Genetics. 92: 807-19. PMID 23623389 DOI: 10.1016/j.ajhg.2013.04.007  0.32
2013 Ju L, Wing J, Taylor E, Brandt R, Slijepcevic P, Horsch M, Rathkolb B, Rácz I, Becker L, Hans W, Adler T, Beckers J, Rozman J, Klingenspor M, Wolf E, ... ... Lehmann AR, et al. SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. Dna Repair. 12: 356-66. PMID 23518413 DOI: 10.1016/j.dnarep.2013.02.006  0.32
2012 Niimi A, Chambers AL, Downs JA, Lehmann AR. A role for chromatin remodellers in replication of damaged DNA. Nucleic Acids Research. 40: 7393-403. PMID 22638582 DOI: 10.1093/nar/gks453  0.32
2012 Lehmann AR. DNA repair, DNA replication and human disorders: a personal journey. Dna Repair. 11: 328-34. PMID 22570876  0.32
2012 Nakazawa Y, Sasaki K, Mitsutake N, Matsuse M, Shimada M, Nardo T, Takahashi Y, Ohyama K, Ito K, Mishima H, Nomura M, Kinoshita A, Ono S, Takenaka K, Masuyama R, ... ... Lehmann AR, et al. Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nature Genetics. 44: 586-92. PMID 22466610 DOI: 10.1038/ng.2229  0.32
2012 Sale JE, Lehmann AR, Woodgate R. Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nature Reviews. Molecular Cell Biology. 13: 141-52. PMID 22358330 DOI: 10.1038/nrm3289  0.32
2011 Lehmann AR, McGibbon D, Stefanini M. Xeroderma pigmentosum. Orphanet Journal of Rare Diseases. 6: 70. PMID 22044607 DOI: 10.1186/1750-1172-6-70  0.32
2011 Sertic S, Pizzi S, Cloney R, Lehmann AR, Marini F, Plevani P, Muzi-Falconi M. Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 13647-52. PMID 21808022 DOI: 10.1073/pnas.1108547108  0.32
2011 Lehmann AR. Ubiquitin-family modifications in the replication of DNA damage. Febs Letters. 585: 2772-9. PMID 21704031 DOI: 10.1016/j.febslet.2011.06.005  0.32
2011 Lehmann AR. DNA polymerases and repair synthesis in NER in human cells. Dna Repair. 10: 730-3. PMID 21601536 DOI: 10.1016/j.dnarep.2011.04.023  0.32
2011 Hudson JJ, Bednarova K, Kozakova L, Liao C, Guerineau M, Colnaghi R, Vidot S, Marek J, Bathula SR, Lehmann AR, Palecek J. Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. Plos One. 6: e17270. PMID 21364888 DOI: 10.1371/journal.pone.0017270  0.32
2011 Göhler T, Sabbioneda S, Green CM, Lehmann AR. ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage. The Journal of Cell Biology. 192: 219-27. PMID 21242293 DOI: 10.1083/jcb.201008076  0.32
2010 Biertümpfel C, Zhao Y, Kondo Y, Ramón-Maiques S, Gregory M, Lee JY, Masutani C, Lehmann AR, Hanaoka F, Yang W. Structure and mechanism of human DNA polymerase eta. Nature. 465: 1044-8. PMID 20577208 DOI: 10.1038/nature09196  0.32
2010 Ramasubramanyan S, Coulon S, Fuchs RP, Lehmann AR, Green CM. Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe. Dna Repair. 9: 777-84. PMID 20452294 DOI: 10.1016/j.dnarep.2010.03.015  0.32
2010 Mari PO, Verbiest V, Sabbioneda S, Gourdin AM, Wijgers N, Dinant C, Lehmann AR, Vermeulen W, Giglia-Mari G. Influence of the live cell DNA marker DRAQ5 on chromatin-associated processes. Dna Repair. 9: 848-55. PMID 20439168 DOI: 10.1016/j.dnarep.2010.04.001  0.32
2010 Ogi T, Limsirichaikul S, Overmeer RM, Volker M, Takenaka K, Cloney R, Nakazawa Y, Niimi A, Miki Y, Jaspers NG, Mullenders LH, Yamashita S, Fousteri MI, Lehmann AR. Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Molecular Cell. 37: 714-27. PMID 20227374 DOI: 10.1016/j.molcel.2010.02.009  0.32
2010 Nakazawa Y, Yamashita S, Lehmann AR, Ogi T. A semi-automated non-radioactive system for measuring recovery of RNA synthesis and unscheduled DNA synthesis using ethynyluracil derivatives. Dna Repair. 9: 506-16. PMID 20171149 DOI: 10.1016/j.dnarep.2010.01.015  0.32
2010 Bienko M, Green CM, Sabbioneda S, Crosetto N, Matic I, Hibbert RG, Begovic T, Niimi A, Mann M, Lehmann AR, Dikic I. Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Molecular Cell. 37: 396-407. PMID 20159558 DOI: 10.1016/j.molcel.2009.12.039  0.32
2010 Laugel V, Dalloz C, Durand M, Sauvanaud F, Kristensen U, Vincent MC, Pasquier L, Odent S, Cormier-Daire V, Gener B, Tobias ES, Tolmie JL, Martin-Coignard D, Drouin-Garraud V, Heron D, ... ... Lehmann AR, et al. Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. Human Mutation. 31: 113-26. PMID 19894250 DOI: 10.1002/humu.21154  0.32
2009 Forsythe E, Wild R, Sellick G, Houlston RS, Lehmann AR, Wakeling E. A novel DNA repair disorder with thrombocytopenia, nephrosis and features overlapping Cockayne syndrome. American Journal of Medical Genetics. Part A. 149: 2075-9. PMID 19760648 DOI: 10.1002/ajmg.a.32995  0.32
2009 Sabbioneda S, Green CM, Bienko M, Kannouche P, Dikic I, Lehmann AR. Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization. Proceedings of the National Academy of Sciences of the United States of America. 106: E20; author reply E2. PMID 19240217 DOI: 10.1073/pnas.0812744106  0.32
2009 Brown S, Niimi A, Lehmann AR. Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork. Cell Cycle (Georgetown, Tex.). 8: 689-92. PMID 19221475  0.32
2009 Lehmann AR. DNA Damage tolerance and translesion synthesis The Dna Damage Response: Implications On Cancer Formation and Treatment. 209-234. DOI: 10.1007/978-90-481-2561-6_10  0.32
2008 Niimi A, Brown S, Sabbioneda S, Kannouche PL, Scott A, Yasui A, Green CM, Lehmann AR. Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16125-30. PMID 18845679 DOI: 10.1073/pnas.0802727105  0.32
2008 Sabbioneda S, Gourdin AM, Green CM, Zotter A, Giglia-Mari G, Houtsmuller A, Vermeulen W, Lehmann AR. Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases. Molecular Biology of the Cell. 19: 5193-202. PMID 18799611 DOI: 10.1091/mbc.E08-07-0724  0.32
2008 Lehmann AR. XPD structure reveals its secrets. Dna Repair. 7: 1912-5. PMID 18692601 DOI: 10.1016/j.dnarep.2008.07.008  0.32
2008 Anttinen A, Koulu L, Nikoskelainen E, Portin R, Kurki T, Erkinjuntti M, Jaspers NG, Raams A, Green MH, Lehmann AR, Wing JF, Arlett CF, Marttila RJ. Neurological symptoms and natural course of xeroderma pigmentosum. Brain : a Journal of Neurology. 131: 1979-89. PMID 18567921 DOI: 10.1093/brain/awn126  0.32
2008 Kleijer WJ, Laugel V, Berneburg M, Nardo T, Fawcett H, Gratchev A, Jaspers NG, Sarasin A, Stefanini M, Lehmann AR. Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Dna Repair. 7: 744-50. PMID 18329345 DOI: 10.1016/j.dnarep.2008.01.014  0.32
2008 Taylor EM, Copsey AC, Hudson JJ, Vidot S, Lehmann AR. Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. Molecular and Cellular Biology. 28: 1197-206. PMID 18086888 DOI: 10.1128/MCB.00767-07  0.32
2008 Arlett CF, Green MH, Rogers PB, Lehmann AR, Plowman PN. Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts. The British Journal of Radiology. 81: 51-8. PMID 18079351 DOI: 10.1259/bjr/27072321  0.32
2007 Lehmann AR, Niimi A, Ogi T, Brown S, Sabbioneda S, Wing JF, Kannouche PL, Green CM. Translesion synthesis: Y-family polymerases and the polymerase switch. Dna Repair. 6: 891-9. PMID 17363342 DOI: 10.1016/j.dnarep.2007.02.003  0.32
2007 Botta E, Offman J, Nardo T, Ricotti R, Zambruno G, Sansone D, Balestri P, Raams A, Kleijer WJ, Jaspers NG, Sarasin A, Lehmann AR, Stefanini M. Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships. Human Mutation. 28: 92-6. PMID 16977596 DOI: 10.1002/humu.20419  0.32
2006 Lehmann AR. New functions for Y family polymerases. Molecular Cell. 24: 493-5. PMID 17188030 DOI: 10.1016/j.molcel.2006.10.021  0.32
2006 Palecek J, Vidot S, Feng M, Doherty AJ, Lehmann AR. The Smc5-Smc6 DNA repair complex. bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits. The Journal of Biological Chemistry. 281: 36952-9. PMID 17005570 DOI: 10.1074/jbc.M608004200  0.32
2006 Lehmann AR, Fuchs RP. Gaps and forks in DNA replication: Rediscovering old models. Dna Repair. 5: 1495-8. PMID 16956796 DOI: 10.1016/j.dnarep.2006.07.002  0.32
2006 Friedberg EC, Aguilera A, Gellert M, Hanawalt PC, Hays JB, Lehmann AR, Lindahl T, Lowndes N, Sarasin A, Wood RD. DNA repair: from molecular mechanism to human disease. Dna Repair. 5: 986-96. PMID 16955546 DOI: 10.1016/j.dnarep.2006.05.005  0.32
2006 Andressoo JO, Mitchell JR, de Wit J, Hoogstraten D, Volker M, Toussaint W, Speksnijder E, Beems RB, van Steeg H, Jans J, de Zeeuw CI, Jaspers NG, Raams A, Lehmann AR, Vermeulen W, et al. An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria. Cancer Cell. 10: 121-32. PMID 16904611 DOI: 10.1016/j.ccr.2006.05.027  0.32
2006 Lehmann AR. Translesion synthesis in mammalian cells. Experimental Cell Research. 312: 2673-6. PMID 16854411 DOI: 10.1016/j.yexcr.2006.06.010  0.32
2006 Sidwell RU, Sandison A, Wing J, Fawcett HD, Seet JE, Fisher C, Nardo T, Stefanini M, Lehmann AR, Cream JJ. A novel mutation in the XPA gene associated with unusually mild clinical features in a patient who developed a spindle cell melanoma. The British Journal of Dermatology. 155: 81-8. PMID 16792756 DOI: 10.1111/j.1365-2133.2006.07272.x  0.32
2006 Ogi T, Lehmann AR. The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Nature Cell Biology. 8: 640-2. PMID 16738703 DOI: 10.1038/ncb1417  0.32
2006 Frampton J, Irmisch A, Green CM, Neiss A, Trickey M, Ulrich HD, Furuya K, Watts FZ, Carr AM, Lehmann AR. Postreplication repair and PCNA modification in Schizosaccharomyces pombe. Molecular Biology of the Cell. 17: 2976-85. PMID 16641370 DOI: 10.1091/mbc.E05-11-1008  0.32
2006 Lehmann AR. Clubbing together on clamps: The key to translesion synthesis. Dna Repair. 5: 404-7. PMID 16427367 DOI: 10.1016/j.dnarep.2005.12.005  0.32
2005 Green CM, Lehmann AR. Translesion synthesis and error-prone polymerases. Advances in Experimental Medicine and Biology. 570: 199-223. PMID 18727502 DOI: 10.1007/1-4020-3764-3_7  0.32
2005 Bienko M, Green CM, Crosetto N, Rudolf F, Zapart G, Coull B, Kannouche P, Wider G, Peter M, Lehmann AR, Hofmann K, Dikic I. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science (New York, N.Y.). 310: 1821-4. PMID 16357261 DOI: 10.1126/science.1120615  0.32
2005 Albertella MR, Green CM, Lehmann AR, O'Connor MJ. A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Cancer Research. 65: 9799-806. PMID 16267001 DOI: 10.1158/0008-5472.CAN-05-1095  0.32
2005 Theron T, Fousteri MI, Volker M, Harries LW, Botta E, Stefanini M, Fujimoto M, Andressoo JO, Mitchell J, Jaspers NG, McDaniel LD, Mullenders LH, Lehmann AR. Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome. Molecular and Cellular Biology. 25: 8368-78. PMID 16135823 DOI: 10.1128/MCB.25.18.8368-8378.2005  0.32
2005 Friedberg EC, Lehmann AR, Fuchs RP. Trading places: how do DNA polymerases switch during translesion DNA synthesis? Molecular Cell. 18: 499-505. PMID 15916957 DOI: 10.1016/j.molcel.2005.03.032  0.32
2005 Lehmann AR. Replication of damaged DNA by translesion synthesis in human cells. Febs Letters. 579: 873-6. PMID 15680966 DOI: 10.1016/j.febslet.2004.11.029  0.32
2005 Lehmann AR. The role of SMC proteins in the responses to DNA damage. Dna Repair. 4: 309-14. PMID 15661654 DOI: 10.1016/j.dnarep.2004.07.009  0.32
2005 Andrews EA, Palecek J, Sergeant J, Taylor E, Lehmann AR, Watts FZ. Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Molecular and Cellular Biology. 25: 185-96. PMID 15601841 DOI: 10.1128/MCB.25.1.185-196.2005  0.32
2005 Sergeant J, Taylor E, Palecek J, Fousteri M, Andrews EA, Sweeney S, Shinagawa H, Watts FZ, Lehmann AR. Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex. Molecular and Cellular Biology. 25: 172-84. PMID 15601840 DOI: 10.1128/MCB.25.1.172-184.2005  0.32
2005 Ogi T, Kannouche P, Lehmann AR. Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci. Journal of Cell Science. 118: 129-36. PMID 15601657 DOI: 10.1242/jcs.01603  0.32
2004 Vaisman A, Lehmann AR, Woodgate R. DNA polymerases eta and iota. Advances in Protein Chemistry. 69: 205-28. PMID 15588844 DOI: 10.1016/S0065-3233(04)69007-3  0.32
2004 Shiloh Y, Lehmann AR. Maintaining integrity. Nature Cell Biology. 6: 923-8. PMID 15459720 DOI: 10.1038/ncb1004-923  0.32
2004 Tissier A, Kannouche P, Reck MP, Lehmann AR, Fuchs RP, Cordonnier A. Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. Dna Repair. 3: 1503-14. PMID 15380106 DOI: 10.1016/j.dnarep.2004.06.015  0.32
2004 Vidal AE, Kannouche P, Podust VN, Yang W, Lehmann AR, Woodgate R. Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. The Journal of Biological Chemistry. 279: 48360-8. PMID 15342632 DOI: 10.1074/jbc.M406511200  0.32
2004 Kannouche PL, Lehmann AR. Ubiquitination of PCNA and the polymerase switch in human cells. Cell Cycle (Georgetown, Tex.). 3: 1011-3. PMID 15280666  0.32
2004 Kannouche PL, Wing J, Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Molecular Cell. 14: 491-500. PMID 15149598 DOI: 10.1016/S1097-2765(04)00259-X  0.32
2003 Lehmann AR. DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Biochimie. 85: 1101-11. PMID 14726016 DOI: 10.1016/j.biochi.2003.09.010  0.32
2003 Taylor ER, Dornan ES, Boner W, Connolly JA, McNair S, Kannouche P, Lehmann AR, Morgan IM. The fidelity of HPV16 E1/E2-mediated DNA replication. The Journal of Biological Chemistry. 278: 52223-30. PMID 14559922 DOI: 10.1074/jbc.M308779200  0.32
2003 Lehmann AR. Replication of damaged DNA. Cell Cycle (Georgetown, Tex.). 2: 300-2. PMID 12851478  0.32
2003 Stary A, Kannouche P, Lehmann AR, Sarasin A. Role of DNA polymerase eta in the UV mutation spectrum in human cells. The Journal of Biological Chemistry. 278: 18767-75. PMID 12644471 DOI: 10.1074/jbc.M211838200  0.32
2003 Kannouche P, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR. Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. The Embo Journal. 22: 1223-33. PMID 12606586 DOI: 10.1093/emboj/cdf618  0.32
2002 Lehmann AR. Replication of damaged DNA in mammalian cells: new solutions to an old problem. Mutation Research. 509: 23-34. PMID 12427529 DOI: 10.1016/S0027-5107(02)00227-0  0.32
2002 Kannouche P, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR. Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. The Embo Journal. 21: 6246-56. PMID 12426396  0.32
2002 Botta E, Nardo T, Lehmann AR, Egly JM, Pedrini AM, Stefanini M. Expression analysis of RSK gene family members: The RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning Human Molecular Genetics. 11: 2929-2940. PMID 12393804  0.32
2002 Broughton BC, Cordonnier A, Kleijer WJ, Jaspers NG, Fawcett H, Raams A, Garritsen VH, Stary A, Avril MF, Boudsocq F, Masutani C, Hanaoka F, Fuchs RP, Sarasin A, Lehmann AR. Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Proceedings of the National Academy of Sciences of the United States of America. 99: 815-20. PMID 11773631 DOI: 10.1073/pnas.022473899  0.32
2001 Viprakasit V, Gibbons RJ, Broughton BC, Tolmie JL, Brown D, Lunt P, Winter RM, Marinoni S, Stefanini M, Brueton L, Lehmann AR, Higgs DR. Mutations in the general transcription factor TFIIH result in beta-thalassaemia in individuals with trichothiodystrophy. Human Molecular Genetics. 10: 2797-802. PMID 11734544  0.32
2001 Broughton BC, Berneburg M, Fawcett H, Taylor EM, Arlett CF, Nardo T, Stefanini M, Menefee E, Price VH, Queille S, Sarasin A, Bohnert E, Krutmann J, Davidson R, Kraemer KH, ... Lehmann AR, et al. Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene. Human Molecular Genetics. 10: 2539-47. PMID 11709541  0.32
2001 Taylor EM, Moghraby JS, Lees JH, Smit B, Moens PB, Lehmann AR. Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex. Molecular Biology of the Cell. 12: 1583-94. PMID 11408570  0.32
2001 Zeng X, Winter DB, Kasmer C, Kraemer KH, Lehmann AR, Gearhart PJ. DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nature Immunology. 2: 537-41. PMID 11376341 DOI: 10.1038/88740  0.32
2001 Kannouche P, Broughton BC, Volker M, Hanaoka F, Mullenders LH, Lehmann AR. Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes & Development. 15: 158-72. PMID 11157773 DOI: 10.1101/gad.187501  0.32
2001 Lehmann AR. The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases. Genes & Development. 15: 15-23. PMID 11156600 DOI: 10.1101/gad.859501  0.32
2001 Berneburg M, Lehmann AR. Xeroderma pigmentosum and related disorders: defects in DNA repair and transcription. Advances in Genetics. 43: 71-102. PMID 11037299  0.32
2000 Monteiro C, Marcelino LA, Conde AR, Saraiva C, Giphart-Gassler M, De Nooij-van Dalen AG, Van Buuren-van Seggelen V, Van der Keur M, May CA, Cole J, Lehmann AR, Steinsgrimsdottir H, Beare D, Capulas E, Armour JA. Molecular methods for the detection of mutations. Teratogenesis, Carcinogenesis, and Mutagenesis. 20: 357-86. PMID 11074520 DOI: 10.1002/1520-6866(2000)20:6<357::AID-TCM5>3.0.CO;2-G  0.32
2000 Lehmann AR. Replication of UV-damaged DNA: new insights into links between DNA polymerases, mutagenesis and human disease. Gene. 253: 1-12. PMID 10925197 DOI: 10.1016/S0378-1119(00)00250-X  0.32
2000 de Klein A, Muijtjens M, van Os R, Verhoeven Y, Smit B, Carr AM, Lehmann AR, Hoeijmakers JH. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Current Biology : Cb. 10: 479-82. PMID 10801416 DOI: 10.1016/S0960-9822(00)00447-4  0.32
2000 Colella S, Nardo T, Botta E, Lehmann AR, Stefanini M. Identical mutations in the CSB gene associated with either Cockayne syndrome or the DeSanctis-cacchione variant of xeroderma pigmentosum. Human Molecular Genetics. 9: 1171-5. PMID 10767341  0.32
2000 Chavanne F, Broughton BC, Pietra D, Nardo T, Browitt A, Lehmann AR, Stefanini M. Mutations in the XPC gene in families with xeroderma pigmentosum and consequences at the cell, protein, and transcript levels. Cancer Research. 60: 1974-82. PMID 10766188  0.32
2000 Fousteri MI, Lehmann AR. A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein. The Embo Journal. 19: 1691-702. PMID 10747036 DOI: 10.1093/emboj/19.7.1691  0.32
2000 Berneburg M, Lowe JE, Nardo T, Araújo S, Fousteri MI, Green MH, Krutmann J, Wood RD, Stefanini M, Lehmann AR. UV damage causes uncontrolled DNA breakage in cells from patients with combined features of XP-D and Cockayne syndrome. The Embo Journal. 19: 1157-66. PMID 10698956 DOI: 10.1093/emboj/19.5.1157  0.32
2000 Berneburg M, Clingen PH, Harcourt SA, Lowe JE, Taylor EM, Green MH, Krutmann J, Arlett CF, Lehmann AR. The cancer-free phenotype in trichothiodystrophy is unrelated to its repair defect. Cancer Research. 60: 431-8. PMID 10667598  0.32
2000 Karam SM, Costa JC, Jardim L, Pires RF, Lehmann AR, Giugliani R. Cockayne syndrome: Report of a Brazilian family with confirmation of impaired RNA synthesis after UV-irradiation Genetics and Molecular Biology. 23: 273-275.  0.32
1999 McDonald JP, Rapi?-Otrin V, Epstein JA, Broughton BC, Wang X, Lehmann AR, Wolgemuth DJ, Woodgate R. Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta. Genomics. 60: 20-30. PMID 10458907 DOI: 10.1006/geno.1999.5906  0.32
1999 Riballo E, Critchlow SE, Teo SH, Doherty AJ, Priestley A, Broughton B, Kysela B, Beamish H, Plowman N, Arlett CF, Lehmann AR, Jackson SP, Jeggo PA. Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. Current Biology : Cb. 9: 699-702. PMID 10395545 DOI: 10.1016/S0960-9822(99)80311-X  0.32
1999 van Hoffen A, Kalle WH, de Jong-Versteeg A, Lehmann AR, van Zeeland AA, Mullenders LH. Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription. Nucleic Acids Research. 27: 2898-904. PMID 10390531 DOI: 10.1093/nar/27.14.2898  0.32
1999 Colella S, Nardo T, Mallery D, Borrone C, Ricci R, Ruffa G, Lehmann AR, Stefanini M. Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity. Human Molecular Genetics. 8: 935-41. PMID 10196384  0.32
1999 Cordonnier AM, Lehmann AR, Fuchs RP. Impaired translesion synthesis in xeroderma pigmentosum variant extracts. Molecular and Cellular Biology. 19: 2206-11. PMID 10022907  0.32
1998 Botta E, Nardo T, Broughton BC, Marinoni S, Lehmann AR, Stefanini M. Analysis of mutations in the XPD gene in Italian patients with trichothiodystrophy: site of mutation correlates with repair deficiency, but gene dosage appears to determine clinical severity. American Journal of Human Genetics. 63: 1036-48. PMID 9758621 DOI: 10.1086/302063  0.32
1998 Taylor EM, Lehmann AR. Conservation of eukaryotic DNA repair mechanisms. International Journal of Radiation Biology. 74: 277-86. PMID 9737531  0.32
1998 Jeggo PA, Carr AM, Lehmann AR. Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia. Trends in Genetics : Tig. 14: 312-6. PMID 9724963 DOI: 10.1016/S0168-9525(98)01511-X  0.32
1998 de Boer J, de Wit J, van Steeg H, Berg RJ, Morreau H, Visser P, Lehmann AR, Duran M, Hoeijmakers JH, Weeda G. A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy. Molecular Cell. 1: 981-90. PMID 9651581  0.32
1998 Svetlova MP, Solovjeva LV, Nikiforov AA, Chagin VA, Lehmann AR, Tomilin NV. Staurosporine-sensitive protein phosphorylation is required for postreplication DNA repair in human cells. Febs Letters. 428: 23-6. PMID 9645467 DOI: 10.1016/S0014-5793(98)00477-3  0.32
1998 Lehmann AR. Dual functions of DNA repair genes: Molecular, cellular, and clinical implications Bioessays. 20: 146-155. PMID 9631660 DOI: 10.1002/(SICI)1521-1878(199802)20:2<146::AID-BIES7>3.0.CO;2-R  0.32
1998 Mallery DL, Tanganelli B, Colella S, Steingrimsdottir H, Van Gool AJ, Troelstra C, Stefanini M, Lehmann AR. Molecular analysis of mutations in the CSB (ERCC6) gene in patients with cockayne syndrome American Journal of Human Genetics. 62: 77-85. PMID 9443879 DOI: 10.1086/301686  0.32
1997 McDaniel LD, Legerski R, Lehmann AR, Friedberg EC, Schultz RA. Confirmation of homozygosity for a single nucleotide substitution mutation in a cockayne syndrome patient using monoallelic mutation analysis in somatic cell hybrids Human Mutation. 10: 317-321. PMID 9338586 DOI: 10.1002/(SICI)1098-1004(1997)10:4<317::AID-HUMU8>3.0.CO;2-D  0.32
1997 Taylor EM, Broughton BC, Botta E, Stefanini M, Sarasin A, Jaspers NGJ, Fawcett H, Harcourt SA, Arlett CF, Lehmann AR. Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) repair/transcription gene Proceedings of the National Academy of Sciences of the United States of America. 94: 8658-8663. PMID 9238033 DOI: 10.1073/pnas.94.16.8658  0.32
1997 Ahrens C, Grewe M, Berneburg M, Grether-Beck S, Quilliet X, Mezzina M, Sarasin A, Lehmann AR, Arlett CF, Krutmann J. Photocarcinogenesis and inhibition of intercellular adhesion molecule 1 expression in cells of DNA-repair-defective individuals Proceedings of the National Academy of Sciences of the United States of America. 94: 6837-6841. PMID 9192652 DOI: 10.1073/pnas.94.13.6837  0.32
1997 Yonemasu R, McCready SJ, Murray JM, Osman F, Takao M, Yamamoto K, Lehmann AR, Yasui A. Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe Nucleic Acids Research. 25: 1553-1558. PMID 9092661 DOI: 10.1093/nar/25.8.1553  0.32
1997 Singleton BK, Priestley A, Steingrimsdottir H, Gell D, Blunt T, Jackson SP, Lehmann AR, Jeggo PA. Molecular and biochemical characterization of xrs mutants defective in Ku80. Molecular and Cellular Biology. 17: 1264-73. PMID 9032253  0.32
1996 Solovjeva LV, Svetlova MP, Hancock R, Whittle R, Lehmann AR, Bootsma D, Tomilin NV. The dual function of proliferating cell nuclear antigen (PCNA) in response of human cells to UV-damage Tsitologiya. 38: 1294-1302. PMID 9163104  0.32
1996 Lehmann AR, Bridges BA, Hanawalt PC, Johnson RT, Kanaar R, Krokan HE, Kyrtopoulos S, Lambert B, Melton DW, Moustacchi E, Natarajan AT, Radman M, Sarasin A, Seeberg E, Smerdon MJ, et al. Workshop on processing of DNA damage. Mutation Research. 364: 245-70. PMID 8960136 DOI: 10.1016/S0921-8777(96)00037-7  0.32
1996 Stefanini M, Fawcett H, Botta E, Nardo T, Lehmann AR. Genetic analysis of twenty-two patients with Cockayne syndrome Human Genetics. 97: 418-423. PMID 8834235 DOI: 10.1007/s004390050065  0.32
1996 Moriwaki S, Stefanini M, Lehmann AR, Hoeijmakers JH, Robbins JH, Rapin I, Botta E, Tanganelli B, Vermeulen W, Broughton BC, Kraemer KH. DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells. The Journal of Investigative Dermatology. 107: 647-53. PMID 8823375  0.32
1996 Blunt T, Gell D, Fox M, Taccioli GE, Lehmann AR, Jackson SP, Jeggo PA. Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proceedings of the National Academy of Sciences of the United States of America. 93: 10285-90. PMID 8816792 DOI: 10.1073/pnas.93.19.10285  0.32
1996 Lehmann AR. Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe Mutation Research - Dna Repair. 363: 147-161. PMID 8765156 DOI: 10.1016/0921-8777(96)00017-1  0.32
1996 Steingrimsdottir H, Beare D, Cole J, Leal JF, Kostic T, Lopez-Barea J, Dorado G, Lehmann AR. Development of new molecular procedures for the detection of genetic alterations in man. Mutation Research. 353: 109-21. PMID 8692187 DOI: 10.1016/0027-5107(95)00244-8  0.32
1996 Broughton BC, Steingrimsdottir H, Lehmann AR. Five polymorphisms in the coding sequence of the xeroderma pigmentosum group D gene Mutation Research - Dna Repair. 362: 209-211. PMID 8596540 DOI: 10.1016/0921-8777(95)00054-2  0.32
1996 Takayama K, Salazar EP, Broughton BC, Lehmann AR, Sarasin A, Thompson LH, Weber CA. Defects in the DNA repair and transcription gene ERCC2(XPD) in trichothiodystrophy American Journal of Human Genetics. 58: 263-270. PMID 8571952  0.32
1995 Griffiths DJF, Barbet NC, McCready S, Lehmann AR, Carr AM. Fission yeast rad17: A homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins Embo Journal. 14: 5812-5823. PMID 8846774  0.32
1995 Blunt T, Taccioli GE, Priestley A, Hafezparast M, McMillan T, Liu J, Cole CC, White J, Alt FW, Jackson SP, Schurr E, Lehmann AR, Jeggo PA. A YAC Contig Encompassing the XRCC5 (Ku80) DNA Repair Gene and Complementation of Defective Cells by YAC Protoplast Fusion Genomics. 30: 320-328. PMID 8586433 DOI: 10.1006/geno.1995.9871  0.32
1995 Lehmann AR. Nucleotide excision repair and the link with transcription Trends in Biochemical Sciences. 20: 402-405. PMID 8533152 DOI: 10.1016/S0968-0004(00)89088-X  0.32
1995 Lehmann AR, Walicka M, Griffiths DJF, Murray JM, Watts FZ, McCready S, Carr AM. The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair Molecular and Cellular Biology. 15: 7067-7080. PMID 8524274  0.32
1995 Sanford KK, Parshad R, Price FM, Tarone RE, Lehmann AR. G2 phase repair of X-ray-induced chromosomal DNA damage in trichothiodystrophy cells. Mutation Research. 346: 107-14. PMID 7885400 DOI: 10.1016/0165-7992(95)90058-6  0.32
1995 Lehmann AR. Workshop on eukaryotic DNA repair genes and gene products Cancer Research. 55: 968-970. PMID 7850815  0.32
1995 Broughton BC, Thompson AF, Harcourt SA, Vermeulen W, Hoeijmakers JHJ, Botta E, Stefanini M, King MD, Weber CA, Cole J, Arlett CF, Lehmann AR. Molecular and Cellular Analysis of the DMA Repair Defect in a Patient in Xeroderma Pigmentosum Complementation Group D Who Has the Clinical Features of Xeroderma Pigmentosum and Cockayne Syndrome American Journal of Human Genetics. 56: 167-174. PMID 7825573  0.32
1995 Lehmann AR. The molecular biology of nucleotide excision repair and double-strand break repair in eukaryotes Genetic Engineering. 17: 1-19. PMID 7779509  0.32
1995 Steingrimsdottir H, Beare D, Carr AM, Cole J, Lehmann AR. U.v.-hypermutability of xeroderma pigmentosum cells demonstrated with a DNA-based mutation system Oncogene. 10: 2057-2066. PMID 7761106  0.32
1995 Henning KA, Li L, Iyer N, McDaniel LD, Reagan MS, Legerski R, Schultz RA, Stefanini M, Lehmann AR, Mayne LV, Friedberg EC. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH Cell. 82: 555-564. PMID 7664335 DOI: 10.1016/0092-8674(95)90028-4  0.32
1995 Lynch SA, De Berker D, Lehmann AR, Pollitt RJ, Reid MM, Lamb WH. Trichothiodystrophy with sideroblastic anaemia and developmental delay Archives of Disease in Childhood. 73: 249-251. PMID 7492166  0.32
1995 Lehmann AR, Carr AM. The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer Trends in Genetics. 11: 375-377. PMID 7482757 DOI: 10.1016/S0168-9525(00)89112-X  0.32
1994 Tolmie JL, de Bekker D, Dawber R, Galloway C, Gregory DW, Lehmann AR, McClure J, Pollitt RJ, Stephenson JBP. Syndromes associated with trichothiodystrophy Clinical Dysmorphology. 3: 1-14. PMID 8205320  0.32
1994 Carr AM, Schmidt H, Kirchhoff S, Muriel WJ, Sheldrick KS, Griffiths DJ, Basmacioglu CN, Subramani S, Clegg M, Nasim A, Lehmann AR. The rad16 gene of Schizosaccharomyces pombe: A homolog of the RAD1 gene of Saccharomyces cerevisiae Molecular and Cellular Biology. 14: 2029-2040. PMID 8114734  0.32
1994 Taccioli GE, Gottlieb TM, Blunt T, Priestley A, Demengeot J, Mizuta R, Lehmann AR, Alt FW, Jackson SP, Jeggo PA. Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination Science. 265: 1442-1445. PMID 8073286 DOI: 10.1126/science.8073286  0.32
1994 Mezzina M, Eveno E, Chevallier-Lagente O, Benoit A, Carreau M, Vermeulen W, Hoeijmakers JHJ, Stefanini M, Lehmann AR, Weber CA, Sarasin A. Correction by the ERCC2 gene of UV sensitivity and repair deficiency phenotype in a subset of trichothiodystrophy cells Carcinogenesis. 15: 1493-1498. PMID 8055625  0.32
1994 Al-Khodairy F, Fotou E, Sheldrick KS, Griffiths DJF, Lehmann AR, Carr AM. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast Molecular Biology of the Cell. 5: 147-160. PMID 8019001  0.32
1994 Murray JM, Tavassoli M, Al-Harithy R, Sheldrick KS, Lehmann AR, Carr AM, Watts FZ. Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage Molecular and Cellular Biology. 14: 4878-4888. PMID 8007985  0.32
1994 Jeggo PA, Carr AM, Lehmann AR. Cloning human DNA repair genes International Journal of Radiation Biology. 66: 573-577. PMID 7983449 DOI: 10.1080/09553009414551651  0.32
1994 Broughton BC, Steingrimsdottir H, Weber CA, Lehmann AR. Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy Nature Genetics. 7: 189-194. PMID 7920640 DOI: 10.1038/ng0694-189  0.32
1994 Vermeulen W, Van Vuuren AJ, Chipoulet M, Schaeffer L, Appeldoorn E, Weeda G, Jaspers NGJ, Priestley A, Arlett CF, Lehmann AR, Stefanini M, Mezzina M, Sarasin A, Bootsma D, Egly JM, et al. Three unusual repair deficiencies associated with transcription factor BTF2(TFIIH): Evidence for the existence of a transcription syndrome Cold Spring Harbor Symposia On Quantitative Biology. 59: 317-329. PMID 7587084  0.32
1994 Lehmann AR, Bootsma D, Clarkson SG, Cleaver JE, McAlpine PJ, Tanaka K, Thompson LH, Wood RD. Nomenclature of human DNA repair genes Mutation Research-Dna Repair. 315: 41-42. PMID 7517009 DOI: 10.1016/0921-8777(94)90026-4  0.32
1994 Mondello C, Nardo T, Giliani S, Arrand JE, Weber CA, Lehmann AR, Nuzzo F, Stefanini M. Molecular analysis of the XP-D gene in Italian families with patients affected by trichothiodystrophy and xeroderma pigmentosum group D Mutation Research-Dna Repair. 314: 159-165. PMID 7510365 DOI: 10.1016/0921-8777(94)90079-5  0.32
1994 Lehmann AR, Carr AM. DNA damage, repair and the cell cycle Trends in Cell Biology. 4: 24-26. DOI: 10.1016/0962-8924(94)90035-3  0.32
1993 Stefanini M, Lagomarsini P, Giliani S, Nardo T, Botta E, Peserico A, Kleijer WJ, Lehmann AR, Sarasin A. Genetic heterogeneity of the excision repair defect associated with trichothiodystrophy Carcinogenesis. 14: 1101-1105. PMID 8508495  0.32
1993 Carr AM, Sheldrick KS, Murray JM, Al-Harithy R, Watts FZ, Lehmann AR. Evolutionary conservation of excision repair in Schizosaccharomyces pombe: Evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 gene Nucleic Acids Research. 21: 1345-1349. PMID 8464724 DOI: 10.1093/nar/21.6.1345  0.32
1993 Berth-Jones J, Cole J, Lehmann AR, Arlett CF, Graham-Brown RAC. Xeroderma pigmentosum variant: 5 years of tumour suppression by etretinate Journal of the Royal Society of Medicine. 86: 355-356. PMID 8315632  0.32
1993 Hafezparast M, Kaur GP, Zdzienicka M, Athwal RS, Lehmann AR, Jeggo PA. Subchromosomal localization of a gene (XRCC5) involved in double strand break repair to the region 2q34-36 Somatic Cell and Molecular Genetics. 19: 413-421. PMID 8291019 DOI: 10.1007/BF01233246  0.32
1993 Doe CL, Murray JM, Shayeghi M, Hoskins M, Lehmann AR, Carr AM, Watts FZ. Cloning and characterisation of the Schizosaccharomyces pombe rad8 gene, a member of the SNF2 helicase family Nucleic Acids Research. 21: 5964-5971. PMID 8290359 DOI: 10.1093/nar/21.25.5964  0.32
1993 Lehmann AR. Duplicated region of sequence similarity to the human XRCC1 DNA repair gene in the Schizosaccharomyces pombe rad4/cut5 gene Nucleic Acids Research. 21: 5274. PMID 8255785 DOI: 10.1093/nar/21.22.5274  0.32
1993 Muris DFR, Vreeken K, Carr AM, Broughton BC, Lehmann AR, Lohman PHM, Pastink A. Cloning the RAD51 homologue of Schizosaccharomyces pombe Nucleic Acids Research. 21: 4586-4591. PMID 8233794 DOI: 10.1093/nar/21.19.4586  0.32
1993 Stefanini M, Vermeulen W, Weeda G, Giliani S, Nardo T, Mezzina M, Sarasin A, Harper JI, Arlett CF, Hoeijmakers JHJ, Lehmann AR. A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy American Journal of Human Genetics. 53: 817-821. PMID 8213812  0.32
1993 Lindahl T, Prigent C, Barnes DE, Lehmann AR, Satoh MS, Roberts E, Nash RA, Robins P, Daly G. DNA joining in mammalian cells Cold Spring Harbor Symposia On Quantitative Biology. 58: 619-624. PMID 7956076  0.32
1993 McCready S, Carr AM, Lehmann AR. Repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in the fission yeast Schizosaccharomyces pombe Molecular Microbiology. 10: 885-890. PMID 7934850 DOI: 10.1111/j.1365-2958.1993.tb00959.x  0.32
1993 Lehmann AR, Thompson AF, Harcourt SA, Stefanini M, Norris PG. Cockayne's syndrome: Correlation of clinical features with cellular sensitivity of RNA synthesis to UV irradiation Journal of Medical Genetics. 30: 679-682. PMID 7692050  0.32
1993 Steingrimsdottir H, Rowley G, Waugh A, Beare D, Ceccherini I, Cole J, Lehmann AR. Molecular analysis of mutations in the hprt gene in circulating lymphocytes from normal and DNA-repair-deficient donors Mutation Research-Dna Repair. 294: 29-41. PMID 7683756 DOI: 10.1016/0921-8777(93)90055-L  0.32
1992 Barnes DE, Tomkinson AE, Lehmann AR, Webster ADB, Lindahl T. Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents Cell. 69: 495-503. PMID 1581963 DOI: 10.1016/0092-8674(92)90450-Q  0.32
1992 Timms AR, Steingrimsdottir H, Lehmann AR, Bridges BA. Mutant sequences in the rpsL gene of Escherichia coli B/r: Mechanistic implications for spontaneous and ultraviolet light mutagenesis Mgg Molecular & General Genetics. 232: 89-96. PMID 1552908 DOI: 10.1007/BF00299141  0.32
1992 Carr AM, Green MHL, Lehmann AR. Checkpoint policing by p53 [6] Nature. 359: 486. PMID 1406967  0.32
1992 Lehmann AR, Hoeijmakers JHJ, van Zeeland AA, Backendorf CMP, Bridges BA, Collins A, Fuchs RPD, Margison GP, Montesano R, Moustacchi E, Natarajan AT, Radman M, Sarasin A, Seeberg E, Smith CA, et al. Workshop on DNA repair Mutation Research-Dna Repair. 273: 1-28. PMID 1376432 DOI: 10.1016/0921-8777(92)90046-6  0.32
1992 Steingrimsdottir H, Rowley G, Dorado G, Cole J, Lehmann AR. Mutations which alter splicing in the human hypoxanthineguanine phosphoribosyltransferase gene Nucleic Acids Research. 20: 1201-1208. PMID 1373235 DOI: 10.1093/nar/20.6.1201  0.32
1992 Webster ADB, Barnes DE, Lindahl T, Arlett CF, Lehmann AR. Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene The Lancet. 339: 1508-1509. PMID 1351188 DOI: 10.1016/0140-6736(92)91266-B  0.32
1992 Murray JM, Doe CL, Schenk P, Carr AM, Lehmann AR, Watts FZ. Cloning and characterisation of the S.pombe rad15 gene, a homologue to the S.cerevisiae RAD3 and human ERCC2 genes Nucleic Acids Research. 20: 2673-2678. PMID 1319571 DOI: 10.1093/nar/20.11.2673  0.32
1991 Norris PG, Arlett CF, Cole J, Lehmann AR, Hawk JLM. Abnormal erythemal response and elevated T lymphocyte HRPT mutant frequency in Cockayne's syndrome British Journal of Dermatology. 124: 453-460. PMID 2039722  0.32
1991 Dorado G, Steingrimsdottir H, Arlett CF, Lehmann AR. Molecular analysis of ultraviolet-induced mutations in a xeroderma pigmentosum cell line Journal of Molecular Biology. 217: 217-222. PMID 1992158 DOI: 10.1016/0022-2836(91)90533-C  0.32
1991 Lehmann AR, Carr AM, Watts FZ, Murray JM. DNA repair in the fission yeast, Schizosaccharomyces pombe Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 250: 205-210. PMID 1944337 DOI: 10.1016/0027-5107(91)90177-P  0.32
1991 Anstey AV, Arlett CF, Cole J, Norris PG, Hamblin AS, Limb GA, Lehmann AR, Wilkinson JD, Turner M. Long-term survival and preservation of natural killer cell activity in a xeroderma pigmentosum patient with spontaneous regression and multiple deposits of malignant melanoma British Journal of Dermatology. 125: 272-278. PMID 1911321  0.32
1991 Broughton BC, Barbet N, Murray J, Watts FZ, Koken MHM, Lehmann AR, Carr AM. Assignment of ten DNA repair genes from Schizosaccharomyces pombe to chromosomal NotI restriction fragments Mgg Molecular & General Genetics. 228: 470-472. PMID 1896014 DOI: 10.1007/BF00260641  0.32
1991 Murray JM, Carr AM, Lehmann AR, Watts FZ. Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe Nucleic Acids Research. 19: 3525-3531. PMID 1852603 DOI: 10.1093/nar/19.13.3525  0.32
1991 Muriel WJ, Lamb JR, Lehmann AR. UV mutation spectra in cell lines from patients with Cockayne's syndrome and ataxia telangiectasia, using the shuttle vector pZ189 Mutation Research-Dna Repair. 254: 119-123. PMID 1848350 DOI: 10.1016/0921-8777(91)90002-7  0.32
1991 Fenech M, Carr AM, Murray J, Watts FZ, Lehmann AR. Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe; a gene showing short regions of sequence similarity to the human XRCC1 gene Nucleic Acids Research. 19: 6737-6741. PMID 1762905 DOI: 10.1093/nar/19.24.6737  0.32
1990 Broughton BC, Lehmann AR, Harcourt SA, Arlett CF, Sarasin A, Keijer WJ, Beemer FA, Nairn R, Mitchell DL. Relationship between pyrimidine dimers, 6-4 photoproducts, repair synthesis and cell survival: Studies using cells from patients with trichothiodystrophy Mutation Research-Dna Repair. 235: 33-40. PMID 2300071 DOI: 10.1016/0921-8777(90)90020-6  0.32
1990 Norris PG, Astrid Limb G, Hamblin AS, Lehmann AR, Arlett CF, Cole J, Waugh APW, Hawk JLM. Immune function, mutant frequency, and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, cockayne's syndrome, and trichothiodystrophy Journal of Investigative Dermatology. 94: 94-100. PMID 2295840  0.32
1990 Bridges BA, Carr AM, Lehmann AR. Possible methodologies for the detection and study of DNA sequence changes following mutagen exposure: Magnetic enrichment in mutant DNA Mutagenesis. 5: 523-524. PMID 2263210 DOI: 10.1093/mutage/5.6.523  0.32
1990 Lehmann AR, Norris PG. DNA repair deficient photodermatoses Seminars in Dermatology. 9: 55-62. PMID 2203444  0.32
1990 Lehmann AR, Bridges BA. Sunlight-induced cancer: Some new aspects and implications of the xeroderma pigmentosum model British Journal of Dermatology. 122: 115-119. PMID 2186779  0.32
1989 Lehmann AR, Norris PG. Dna repair and cancer: Speculations based on studies with xeroderma pigmentosum, cockayne's syndrome and trichothiodystrophy Carcinogenesis. 10: 1353-1356. PMID 2752510 DOI: 10.1093/carcin/10.8.1353  0.32
1989 Lehmann AR. Trichothiodystrophy and the relationship between DNA repair and cancer Bioessays. 11: 168-170. PMID 2695082 DOI: 10.1002/bies.950110603  0.32
1989 Lehmann AR, Jaspers NGJ, Gatti RA. Fourth international workshop on ataxia-telangiectasia Cancer Research. 49: 6162-6163. PMID 2676158  0.32
1989 Lamb JR, Petit-Frère C, Broughton BC, Lehmann AR, Green MHL. Inhibition of DNA replication by ionizing radiation is mediated by a trans-acting factor International Journal of Radiation Biology. 56: 125-130. PMID 2569014 DOI: 10.1080/09553008914551271  0.32
1989 Dean SW, Kincla L, Sykes HR, Lehmann AR, Wise IA. Instability of extrachromosomal cosmid DNA in SV40-transformed human (ataxia-telangiectasia) cells Experimental Cell Research. 183: 473-483. PMID 2548887 DOI: 10.1016/0014-4827(89)90406-0  0.32
1989 Lehmann AR, Arlett CF, Harcourt SA, Steingrimsdottir H, Gebara MM. Mutagenic treatments result in inactivation of expression of a transfected bacterial gene integrated into a human cell line Mutation Research/Reviews in Genetic Toxicology. 220: 255-262. PMID 2467202 DOI: 10.1016/0165-1110(89)90029-8  0.32
1989 Mayne LV, Jones T, Dean SW, Harcourt SA, Lowe JE, Priestley A, Steingrimsdottir H, Sykes H, Green MHL, Lehmann AR. SV40-transformed normal and DNA-repair-deficient human fibroblasts can be transfected with high frequency but retain only limited amounts of integrated DNA Gene. 83: 395. DOI: 10.1016/0378-1119(88)90225-9  0.32
1988 Lehmann AR, Willis AE, Broughton BC, James MR, Steingrimsdottir H, Harcourt SA, Arlett CF, Lindahl T. Relation between the human fibroblast strain 46BR and cell lines representative of Bloom's syndrome Cancer Research. 48: 6343-6347. PMID 3180052  0.32
1988 Dean SW, Sykes HR, Lehmann AR. Inactivation by nitrogen mustard of plasmids introduced into normal and Fanconi's anaemia cells Mutation Research Dna Repair Reports. 194: 57-63. PMID 3164443 DOI: 10.1016/0167-8817(88)90056-9  0.32
1988 Parris CN, Arlett CF, Lehmann AR, Green MHL, Masters JRW. Differential sensitivities to gamma radiation of human bladder and testicular tumour cell lines International Journal of Radiation Biology. 53: 599-608. PMID 2832339 DOI: 10.1080/09553008814550921  0.32
1988 Lehmann AR, Arlett CF, Broughton BC, Harcourt SA, Steingrimsdottir H, Stefanini M, Taylor AMR, Natarajan AT, Green S, King MD, MacKie RM, Stephenson JBP, Tolmie JL. Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light Cancer Research. 48: 6090-6096. PMID 2458832  0.32
1987 Friedberg EC, Backendorf C, Burke J, Collins A, Grossman L, Hoeijmakers JHJ, Lehmann AR, Seeberg E, van der Schans GP, van Zeeland AA. Molecular aspects of DNA repair. Report of a workshop held at Noordwijkerhout (The Netherlands) 1-5 March 1987, Organized by P.H.M. Lohman, J.W.I.M. Simons, D. Bootsma, J.H.J. Hoeijmakers, B.A. Bridges, P. van de Putte and A.J. van der Eb Mutation Research Dna Repair Reports. 184: 67-86. PMID 3306357  0.32
1987 Gebara MM, Drevon C, Harcourt SA, Steingrimsdottir H, James MR, Burke JF, Arlett CF, Lehmann AR. Inactivation of a transfected gene in human fibroblasts can occur by deletion, amplification, phenotypic switching, or methylation Molecular and Cellular Biology. 7: 1459-1464. PMID 3110595  0.32
1987 Muriel WJ, Cole J, Lehmann AR. Molecular analysis of ouabain-resistant mutants of the mouse lymphoma cell line L5178Y Mutagenesis. 2: 383-389. PMID 2830454 DOI: 10.1093/mutage/2.5.383  0.32
1987 Hilgers G, Abrahams PJ, Schouten R, Cornelis JJ, Lehmann AR, Van Der Eb AJ, Rommelaere J. The cells of patients suffering of ataxia telangiectasia show a normal capacity of radioinduced reactivation of damaged HSV-1 virus | LES CELLULES DE PATIENTS ATTEINTS D'ATAXIA TELANGIECTASIA MANIFESTENT UNE CAPACITE NORMALE DE REACTIVATION RADIOINDUITE DU VIRUS HSV-I ENDOMMAGE Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales. 181: 432-438. PMID 2830002  0.32
1987 Lehmann AR. Cockayne's syndrome and trichothiodystrophy: Defective repair without cancer Cancer Reviews. 7: 82-103.  0.32
1985 Lehmann AR. Ageing, DNA repair of radiation damage and carcinogenesis: fact and fiction Iarc Scientific Publications. 203-213. PMID 3913639  0.32
1985 Henderson LM, Arlett CF, Harcourt SA, Lehmann AR, Broughton BC. Cells from an immunodeficient patient (46BR) with a defect in DNA ligation are hypomutable but hypersensitive to the induction of sister chromatid exchanges. Proceedings of the National Academy of Sciences of the United States of America. 82: 2044-8. PMID 3856882 DOI: 10.1073/pnas.82.7.2044  0.32
1985 Poirier V, James MR, Arlett CF, Lehmann AR. Nad and the synthesis of (ADP-ribose)n in a human cell strain (46BR) hypersensitive to the lethal effects of 3-aminobenzamide Carcinogenesis. 6: 837-841. PMID 2988809 DOI: 10.1093/carcin/6.6.837  0.32
1985 Lehmann AR, Oomen A. Effect of DNA damage on the expression of the chloramphenicol acetyltransferase gene after transfection into diploid human fibroblasts Nucleic Acids Research. 13: 2087-2095. PMID 2987842 DOI: 10.1093/nar/13.6.2087  0.32
1985 Lehmann AR, Francis AJ, Giannelli F. Prenatal diagnosis of Cockayne's syndrome. Lancet (London, England). 1: 486-8. PMID 2579301 DOI: 10.1016/S0140-6736(85)92088-4  0.32
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