Matthew J. O'Connell - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
cell cycle, DNA repair

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lin SJ, Tapia-Alveal C, Jabado OJ, Germain D, O'Connell MJ. An acetyltransferase-independent function of Eso1 regulates centromere cohesion. Molecular Biology of the Cell. PMID 27798241 DOI: 10.1091/Mbc.E16-08-0596  0.68
2014 Tapia-Alveal C, Lin SJ, O'Connell MJ. Functional interplay between cohesin and Smc5/6 complexes. Chromosoma. 123: 437-45. PMID 24981336 DOI: 10.1007/S00412-014-0474-9  1
2014 Barnum KJ, O'Connell MJ. Cell cycle regulation by checkpoints. Methods in Molecular Biology (Clifton, N.J.). 1170: 29-40. PMID 24906307 DOI: 10.1007/978-1-4939-0888-2_2  1
2014 Tapia-Alveal C, Lin SJ, Yeoh A, Jabado OJ, O'Connell MJ. H2A.Z-dependent regulation of cohesin dynamics on chromosome arms. Molecular and Cellular Biology. 34: 2092-104. PMID 24687850 DOI: 10.1128/Mcb.00193-14  1
2013 Caparelli ML, O'Connell MJ. Regulatory motifs in Chk1. Cell Cycle (Georgetown, Tex.). 12: 916-22. PMID 23422000 DOI: 10.4161/cc.23881  1
2013 Kuntz K, O'Connell MJ. Initiation of DNA damage responses through XPG-related nucleases. The Embo Journal. 32: 290-302. PMID 23211746 DOI: 10.1038/Emboj.2012.322  1
2012 Bass KL, Murray JM, O'Connell MJ. Brc1-dependent recovery from replication stress. Journal of Cell Science. 125: 2753-64. PMID 22366461 DOI: 10.1242/Jcs.103119  1
2012 Wang Y, Kallgren SP, Reddy BD, Kuntz K, López-Maury L, Thompson J, Watt S, Ma C, Hou H, Shi Y, Yates JR, Bähler J, O'Connell MJ, Jia S. Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast. The Journal of Biological Chemistry. 287: 4386-93. PMID 22184112 DOI: 10.1074/Jbc.M111.329417  1
2011 Tapia-Alveal C, O'Connell MJ. Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes. Molecular Biology of the Cell. 22: 4669-82. PMID 21976700 DOI: 10.1091/Mbc.E11-03-0272  1
2011 Tapia-Alveal C, O'Connell MJ. Methods for studying checkpoint kinases - Chk1. Methods in Molecular Biology (Clifton, N.J.). 782: 171-9. PMID 21870291 DOI: 10.1007/978-1-61779-273-1_12  1
2011 Tapia-Alveal C, O'Connell MJ. Methods for studying the G2 DNA damage checkpoint in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 782: 23-31. PMID 21870282 DOI: 10.1007/978-1-61779-273-1_3  1
2010 Tapia-Alveal C, Outwin EA, Trempolec N, Dziadkowiec D, Murray JM, O'Connell MJ. SMC complexes and topoisomerase II work together so that sister chromatids can work apart. Cell Cycle (Georgetown, Tex.). 9: 2065-70. PMID 20495382 DOI: 10.4161/Cc.9.11.11734  1
2010 Calonge TM, Eshaghi M, Liu J, Ronai Z, O'Connell MJ. Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1. Genetics. 185: 81-93. PMID 20194963 DOI: 10.1534/Genetics.110.114769  1
2009 Kuntz K, O'Connell MJ. The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer? Cancer Biology & Therapy. 8: 1433-9. PMID 19574738 DOI: 10.4161/Cbt.8.15.9081  1
2009 Outwin EA, Irmisch A, Murray JM, O'Connell MJ. Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes. Molecular and Cellular Biology. 29: 4363-75. PMID 19528228 DOI: 10.1128/Mcb.00377-09  1
2009 Tapia-Alveal C, Calonge TM, O'Connell MJ. Regulation of chk1. Cell Division. 4: 8. PMID 19400965 DOI: 10.1186/1747-1028-4-8  1
2009 Irmisch A, Ampatzidou E, Mizuno K, O'Connell MJ, Murray JM. Smc5/6 maintains stalled replication forks in a recombination-competent conformation. The Embo Journal. 28: 144-55. PMID 19158664 DOI: 10.1038/Emboj.2008.273  1
2008 Bhoumik A, Singha N, O'Connell MJ, Ronai ZA. Regulation of TIP60 by ATF2 modulates ATM activation. The Journal of Biological Chemistry. 283: 17605-14. PMID 18397884 DOI: 10.1074/Jbc.M802030200  1
2008 Calonge TM, O'Connell MJ. Turning off the G2 DNA damage checkpoint. Dna Repair. 7: 136-40. PMID 17851138 DOI: 10.1016/j.dnarep.2007.07.017  1
2007 Umanskaya K, Radke S, Chander H, Monardo R, Xu X, Pan ZQ, O'Connell MJ, Germain D. Skp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptor. Molecular and Cellular Biology. 27: 7615-22. PMID 17785450 DOI: 10.1128/Mcb.01239-07  1
2007 Kosoy A, Calonge TM, Outwin EA, O'Connell MJ. Fission yeast Rnf4 homologs are required for DNA repair. The Journal of Biological Chemistry. 282: 20388-94. PMID 17502373 DOI: 10.1074/Jbc.M702652200  1
2007 Lee KM, Nizza S, Hayes T, Bass KL, Irmisch A, Murray JM, O'Connell MJ. Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. Genetics. 175: 1585-95. PMID 17277362 DOI: 10.1534/Genetics.106.067801  1
2006 Ampatzidou E, Irmisch A, O'Connell MJ, Murray JM. Smc5/6 is required for repair at collapsed replication forks. Molecular and Cellular Biology. 26: 9387-401. PMID 17030601 DOI: 10.1128/Mcb.01335-06  1
2006 Ishii Y, Pirkmaier A, Alvarez JV, Frank DA, Keselman I, Logothetis D, Mandeli J, O'Connell MJ, Waxman S, Germain D. Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model. Journal of the National Cancer Institute. 98: 1238-47. PMID 16954476 DOI: 10.1093/Jnci/Djj334  1
2006 Calonge TM, O'Connell MJ. Antagonism of Chk1 signaling in the G2 DNA damage checkpoint by dominant alleles of Cdr1. Genetics. 174: 113-23. PMID 16816416 DOI: 10.1534/Genetics.106.060970  1
2006 Macip S, Kosoy A, Lee SW, O'Connell MJ, Aaronson SA. Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint Oncogene. 25: 6037-6047. PMID 16652144 DOI: 10.1038/Sj.Onc.1209629  1
2006 Lee KM, O'Connell MJ. A new SUMO ligase in the DNA damage response. Dna Repair. 5: 138-41. PMID 16198156 DOI: 10.1016/j.dnarep.2005.08.003  1
2005 Sheedy DM, Dimitrova D, Rankin JK, Bass KL, Lee KM, Tapia-Alveal C, Harvey SH, Murray JM, O'Connell MJ. Brc1-mediated DNA repair and damage tolerance. Genetics. 171: 457-68. PMID 15972456 DOI: 10.1534/Genetics.105.044966  1
2005 Bimbó A, Jia Y, Poh SL, Karuturi RK, den Elzen N, Peng X, Zheng L, O'Connell M, Liu ET, Balasubramanian MK, Liu J. Systematic deletion analysis of fission yeast protein kinases. Eukaryotic Cell. 4: 799-813. PMID 15821139 DOI: 10.1128/Ec.4.4.799-813.2005  1
2005 O'Connell MJ, Cimprich KA. G2 damage checkpoints: what is the turn-on? Journal of Cell Science. 118: 1-6. PMID 15615778 DOI: 10.1242/Jcs.01626  1
2004 Latif C, den Elzen NR, O'Connell MJ. DNA damage checkpoint maintenance through sustained Chk1 activity. Journal of Cell Science. 117: 3489-98. PMID 15213253 DOI: 10.1242/Jcs.01204  1
2004 den Elzen N, Kosoy A, Christopoulos H, O'Connell MJ. Resisting arrest: recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1. Cell Cycle (Georgetown, Tex.). 3: 529-33. PMID 15020842  1
2004 den Elzen NR, O'Connell MJ. Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1. The Embo Journal. 23: 908-18. PMID 14765108 DOI: 10.1038/Sj.Emboj.7600105  1
2004 Mochida S, Esashi F, Aono N, Tamai K, O'Connell MJ, Yanagida M. Regulation of checkpoint kinases through dynamic interaction with Crb2. The Embo Journal. 23: 418-28. PMID 14739927 DOI: 10.1038/Sj.Emboj.7600018  1
2004 Harvey SH, Sheedy DM, Cuddihy AR, O'Connell MJ. Coordination of DNA damage responses via the Smc5/Smc6 complex. Molecular and Cellular Biology. 24: 662-74. PMID 14701739 DOI: 10.1128/MCB.24.2.662-674.2004  1
2003 O'Connell MJ, Krien MJ, Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends in Cell Biology. 13: 221-8. PMID 12742165 DOI: 10.1016/S0962-8924(03)00056-4  1
2003 Pirkmaier A, Yuen K, Hendley J, O'Connell MJ, Germain D. Cyclin d1 overexpression sensitizes breast cancer cells to fenretinide. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1877-84. PMID 12738746  1
2003 Cuddihy AR, O'Connell MJ. Cell-cycle responses to DNA damage in G2. International Review of Cytology. 222: 99-140. PMID 12503848 DOI: 10.1016/S0074-7696(02)22013-6  1
2002 Frew IJ, Dickins RA, Cuddihy AR, Del Rosario M, Reinhard C, O'Connell MJ, Bowtell DD. Normal p53 function in primary cells deficient for Siah genes. Molecular and Cellular Biology. 22: 8155-64. PMID 12417719 DOI: 10.1128/Mcb.22.23.8155-8164.2002  1
2002 Krien MJ, West RR, John UP, Koniaras K, McIntosh JR, O'Connell MJ. The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity. The Embo Journal. 21: 1713-22. PMID 11927555 DOI: 10.1093/Emboj/21.7.1713  1
2002 Harvey SH, Krien MJ, O'Connell MJ. Structural maintenance of chromosomes (SMC) proteins, a family of conserved ATPases. Genome Biology. 3: REVIEWS3003. PMID 11864377 DOI: 10.1186/Gb-2002-3-2-Reviews3003  1
2001 Latif C, Harvey SH, O'Connell MJ. Ensuring the stability of the genome: DNA damage checkpoints Thescientificworldjournal [Electronic Resource]. 1: 684-702. PMID 12805771  1
2001 Koniaras K, Cuddihy AR, Christopoulos H, Hogg A, O'Connell MJ. Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells Oncogene. 20: 7453-7463. PMID 11709716 DOI: 10.1038/sj.onc.1204942  1
2001 Huang HK, Forsburg SL, John UP, O'Connell MJ, Hunter T. Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe. Journal of Cell Science. 114: 3779-88. PMID 11707530  1
2001 Verkade HM, Teli T, Laursen LV, Murray JM, O'Connell MJ. A homologue of the Rad18 postreplication repair gene is required for DNA damage responses throughout the fission yeast cell cycle Molecular Genetics and Genomics. 265: 993-1003. PMID 11523791 DOI: 10.1007/s004380100494  1
2000 O'Connell MJ, Walworth NC, Carr AM. The G2-phase DNA-damage checkpoint. Trends in Cell Biology. 10: 296-303. PMID 10856933 DOI: 10.1016/S0962-8924(00)01773-6  1
2000 Raleigh JM, O'Connell MJ. The G2 DNA damage checkpoint targets both Wee1 and Cdc25 Journal of Cell Science. 113: 1727-1736. PMID 10769204  1
1999 Verkade HM, Bugg SJ, Lindsay HD, Carr AM, O'Connell MJ. Rad18 is required for DNA repair and checkpoint responses in fission yeast Molecular Biology of the Cell. 10: 2905-2918. PMID 10473635  1
1999 Uren AG, Beilharz T, O'Connell MJ, Bugg SJ, Van Driel R, Vaux DL, Lithgow T. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division Proceedings of the National Academy of Sciences of the United States of America. 96: 10170-10175. PMID 10468581 DOI: 10.1073/Pnas.96.18.10170  1
1999 Ha SB, Smith AP, Howden R, Dietrich WM, Bugg S, O'Connell MJ, Goldsbrough PB, Cobbett CS. Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe Plant Cell. 11: 1153-1163. PMID 10368185 DOI: 10.1105/Tpc.11.6.1153  1
1999 Chen P, Gatei M, O'Connell MJ, Khanna KK, Bugg SJ, Hogg A, Scott SP, Hobson K, Lavin MF. Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells Oncogene. 18: 249-256. PMID 9926940 DOI: 10.1038/sj.onc.1202257  1
1998 Verkade HM, O'Connell MJ. Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast Molecular and General Genetics. 260: 426-433. PMID 9894912 DOI: 10.1007/s004380050913  1
1998 Krien MJE, Bugg SJ, Palatsides M, Asouline G, Morimyo M, O'Connell MJ. A NIMA homologue promotes chromatin condensation in fission yeast Journal of Cell Science. 111: 967-976. PMID 9490640  1
1998 Lies CM, Cheng J, James SW, Morris NR, O'Connell MJ, Mirabito PM. BIMA(APC3), component of the Aspergillus anaphase promoting complex/cyclosome, is required for a G2 checkpoint blocking entry into mitosis in the absence of NIMA function Journal of Cell Science. 111: 1453-1465.  1
1997 O'Connell MJ, Raleigh JM, Verkade HM, Nurse P. Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation Embo Journal. 16: 545-554. PMID 9034337 DOI: 10.1093/Emboj/16.3.545  1
1994 Osmani AH, Van Peij N, Mischke M, O'Connell MJ, Osmani SA. A single p34cdc2 protein kinase (encoded by nimXcdc2) is required at G1 and G2 in Aspergillus nidulans Journal of Cell Science. 107: 1519-1528. PMID 7962194  1
1994 O'Connell MJ, Norbury C, Nurse P. Premature chromatin condensation upon accumulation of NIMA Embo Journal. 13: 4926-4937. PMID 7957060 DOI: 10.1002/J.1460-2075.1994.Tb06820.X  1
1994 O'Connell MJ, Nurse P. How cells know they are in G1 or G2 Current Opinion in Cell Biology. 6: 867-871. PMID 7880535 DOI: 10.1016/0955-0674(94)90058-2  1
1993 O'Connell MJ, Meluh PB, Rose MD, Morris NR. Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans. The Journal of Cell Biology. 120: 153-62. PMID 8416986 DOI: 10.1083/Jcb.120.1.153  1
1992 O'Connell MJ, Kelly JM. Cis-acting control elements 5′ to aldA, the aldehyde dehydrogenase-encoding gene of Aspergillus niger Gene. 117: 151-156. PMID 1644309 DOI: 10.1016/0378-1119(92)90505-J  1
1992 O'Connell MJ, Osmani AH, Ronald Morris N, Osmani SA. An extra copy of nimEcyclinB elevates pre-MPF levels and partially suppresses mutation of nimTcdc25 in Aspergillus nidulans Embo Journal. 11: 2139-2149. PMID 1534750  1
1991 Enos AP, O'Connell M, Morris NR. Kinesin-like proteins of Aspergillus nidulans Cold Spring Harbor Symposia On Quantitative Biology. 56: 643-648. PMID 1819513  1
1989 O'Connell MJ, Kelly JM. Physical characterization of the aldehyde-dehydrogenase-encoding gene of Aspergillus niger Gene. 84: 173-180. PMID 2606357 DOI: 10.1016/0378-1119(89)90152-2  1
1988 O'Connell MJ, Kelly JM. Differences in the regulation of aldehyde dehydrogenase genes in Aspergillus niger and Aspergillus nidulans Current Genetics. 14: 95-103. PMID 2846191 DOI: 10.1007/Bf00569332  1
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