Charlie S. Hoffman - Publications

Boston College, Newton, MA, United States 
glucose signaling, cAMP, phosphodiesterases

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hoffman CS, Wood V, Fantes PA. An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System. Genetics. 201: 403-23. PMID 26447128 DOI: 10.1534/genetics.115.181503  1
2015 de Medeiros AS, Hoffman CS. A yeast-based high-throughput screen for modulators of phosphodiesterase activity. Methods in Molecular Biology (Clifton, N.J.). 1294: 181-90. PMID 25783886 DOI: 10.1007/978-1-4939-2537-7_14  1
2015 de Medeiros AS, Kwak G, Vanderhooft J, Rivera S, Gottlieb R, Hoffman CS. Fission yeast-based high-throughput screens for PKA pathway inhibitors and activators. Methods in Molecular Biology (Clifton, N.J.). 1263: 77-91. PMID 25618337 DOI: 10.1007/978-1-4939-2269-7_6  1
2015 Asada R, Takemata N, Hoffman CS, Ohta K, Hirota K. Antagonistic controls of chromatin and mRNA start site selection by Tup family corepressors and the CCAAT-binding factor. Molecular and Cellular Biology. 35: 847-55. PMID 25535331 DOI: 10.1128/MCB.00924-14  1
2014 Mudge DK, Yang F, Currie BM, Kim JM, Yeda K, Bashyakarla VK, Ivey FD, Hoffman CS. Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe. Eukaryotic Cell. 13: 202-8. PMID 24297439 DOI: 10.1128/EC.00277-13  1
2013 de Medeiros AS, Magee A, Nelson K, Friedberg L, Trocka K, Hoffman CS. Use of PKA-mediated phenotypes for genetic and small-molecule screens in Schizosaccharomyces pombe. Biochemical Society Transactions. 41: 1692-5. PMID 24256276 DOI: 10.1042/BST20130159  1
2013 Demirbas D, Wyman AR, Shimizu-Albergine M, Cakici O, Beavo JA, Hoffman CS. A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition. Plos One. 8: e71279. PMID 23967182 DOI: 10.1371/journal.pone.0071279  1
2012 Tong K, Keller T, Hoffman CS, Annunziato AT. Schizosaccharomyces pombe Hat1 (Kat1) is associated with Mis16 and is required for telomeric silencing. Eukaryotic Cell. 11: 1095-103. PMID 22771823 DOI: 10.1128/EC.00123-12  1
2012 Ceyhan O, Birsoy K, Hoffman CS. Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chemistry & Biology. 19: 155-63. PMID 22284362 DOI: 10.1016/j.chembiol.2011.12.010  1
2012 Mudge DK, Hoffman CA, Lubinski TJ, Hoffman CS. Use of a ura5+-lys7+ cassette to construct unmarked gene knock-ins in Schizosaccharomyces pombe. Current Genetics. 58: 59-64. PMID 22198627 DOI: 10.1007/s00294-011-0360-4  1
2011 Demirbas D, Ceyhan O, Wyman AR, Hoffman CS. A fission yeast-based platform for phosphodiesterase inhibitor HTSs and analyses of phosphodiesterase activity. Handbook of Experimental Pharmacology. 135-49. PMID 21695638 DOI: 10.1007/978-3-642-17969-3_5  1
2011 Demirbas D, Ceyhan O, Wyman AR, Ivey FD, Allain C, Wang L, Sharuk MN, Francis SH, Hoffman CS. Use of a Schizosaccharomyces pombe PKA-repressible reporter to study cGMP metabolising phosphodiesterases. Cellular Signalling. 23: 594-601. PMID 21118717 DOI: 10.1016/j.cellsig.2010.11.013  1
2010 Alaamery MA, Wyman AR, Ivey FD, Allain C, Demirbas D, Wang L, Ceyhan O, Hoffman CS. New classes of PDE7 inhibitors identified by a fission yeast-based HTS. Journal of Biomolecular Screening. 15: 359-67. PMID 20228279 DOI: 10.1177/1087057110362100  1
2010 Ivey FD, Taglia FX, Yang F, Lander MM, Kelly DA, Hoffman CS. Activated alleles of the Schizosaccharomyces pombe gpa2+ Galpha gene identify residues involved in GDP-GTP exchange. Eukaryotic Cell. 9: 626-33. PMID 20139237 DOI: 10.1128/EC.00010-10  1
2009 Roux AE, Leroux A, Alaamery MA, Hoffman CS, Chartrand P, Ferbeyre G, Rokeach LA. Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast. Plos Genetics. 5: e1000408. PMID 19266076 DOI: 10.1371/journal.pgen.1000408  1
2008 Hirota K, Miyoshi T, Kugou K, Hoffman CS, Shibata T, Ohta K. Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs. Nature. 456: 130-4. PMID 18820678 DOI: 10.1038/nature07348  1
2008 Alaamery MA, Hoffman CS. Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling. Genetics. 178: 1927-36. PMID 18430926 DOI: 10.1534/genetics.107.086165  1
2008 Leem YE, Ripmaster TL, Kelly FD, Ebina H, Heincelman ME, Zhang K, Grewal SI, Hoffman CS, Levin HL. Retrotransposon Tf1 is targeted to Pol II promoters by transcription activators. Molecular Cell. 30: 98-107. PMID 18406330 DOI: 10.1016/j.molcel.2008.02.016  1
2008 Ivey FD, Wang L, Demirbas D, Allain C, Hoffman CS. Development of a fission yeast-based high-throughput screen to identify chemical regulators of cAMP phosphodiesterases. Journal of Biomolecular Screening. 13: 62-71. PMID 18227226 DOI: 10.1177/1087057107312127  1
2007 Hoffman CS. Propping up our knowledge of G protein signaling pathways: diverse functions of putative noncanonical Gbeta subunits in fungi. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe3. PMID 17244888 DOI: 10.1126/stke.3702007pe3  1
2007 Benson LJ, Phillips JA, Gu Y, Parthun MR, Hoffman CS, Annunziato AT. Properties of the type B histone acetyltransferase Hat1: H4 tail interaction, site preference, and involvement in DNA repair. The Journal of Biological Chemistry. 282: 836-42. PMID 17052979 DOI: 10.1074/jbc.M607464200  1
2006 Hirota K, Hoffman CS, Ohta K. Reciprocal nuclear shuttling of two antagonizing Zn finger proteins modulates Tup family corepressor function to repress chromatin remodeling. Eukaryotic Cell. 5: 1980-9. PMID 17028240 DOI: 10.1128/EC.00272-06  1
2006 Hoffman RL, Hoffman CS. Cloning the Schizosaccharomyces pombe lys2+ gene and construction of new molecular genetic tools. Current Genetics. 49: 414-20. PMID 16491385 DOI: 10.1007/s00294-006-0065-2  1
2006 Kao RS, Morreale E, Wang L, Ivey FD, Hoffman CS. Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase. Genetics. 173: 49-61. PMID 16489217 DOI: 10.1534/genetics.106.055699  1
2005 Wang L, Griffiths K, Zhang YH, Ivey FD, Hoffman CS. Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling. Genetics. 171: 1523-33. PMID 16143612 DOI: 10.1534/genetics.105.047233  1
2005 Ivey FD, Hoffman CS. Direct activation of fission yeast adenylate cyclase by the Gpa2 Galpha of the glucose signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 6108-13. PMID 15831585 DOI: 10.1073/pnas.0502270102  1
2005 Hoffman CS. Except in every detail: comparing and contrasting G-protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Eukaryotic Cell. 4: 495-503. PMID 15755912 DOI: 10.1128/EC.4.3.495-503.2005  1
2005 Hoffman CS. Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombe. Biochemical Society Transactions. 33: 257-60. PMID 15667320 DOI: 10.1042/BST0330257  1
2004 Stiefel J, Wang L, Kelly DA, Janoo RT, Seitz J, Whitehall SK, Hoffman CS. Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe. Eukaryotic Cell. 3: 610-9. PMID 15189983 DOI: 10.1128/EC.3.3.610-619.2004  1
2004 Wang L, Kao R, Ivey FD, Hoffman CS. Strategies for gene disruptions and plasmid constructions in fission yeast. Methods (San Diego, Calif.). 33: 199-205. PMID 15157886 DOI: 10.1016/j.ymeth.2003.11.014  1
2004 Hirota K, Hasemi T, Yamada T, Mizuno KI, Hoffman CS, Shibata T, Ohta K. Fission yeast global repressors regulate the specificity of chromatin alteration in response to distinct environmental stresses. Nucleic Acids Research. 32: 855-62. PMID 14762213 DOI: 10.1093/nar/gkh251  1
2003 Hirota K, Hoffman CS, Shibata T, Ohta K. Fission yeast Tup1-like repressors repress chromatin remodeling at the fbp1+ promoter and the ade6-M26 recombination hotspot. Genetics. 165: 505-15. PMID 14573465  1
2003 Yang P, Du H, Hoffman CS, Marcus S. The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe. Molecular Genetics and Genomics : Mgg. 269: 116-25. PMID 12715160 DOI: 10.1007/s00438-003-0820-8  1
2002 Schadick K, Fourcade HM, Boumenot P, Seitz JJ, Morrell JL, Chang L, Gould KL, Partridge JF, Allshire RC, Kitagawa K, Hieter P, Hoffman CS. Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation. Eukaryotic Cell. 1: 558-67. PMID 12456004 DOI: 10.1128/EC.1.4.558-567.2002  1
2002 Takagi T, Cho EJ, Janoo RT, Polodny V, Takase Y, Keogh MC, Woo SA, Fresco-Cohen LD, Hoffman CS, Buratowski S. Divergent subunit interactions among fungal mRNA 5'-capping machineries. Eukaryotic Cell. 1: 448-57. PMID 12455993 DOI: 10.1128/EC.1.3.448-457.2002  1
2002 Kelly DA, Hoffman CS. Gap repair transformation in fission yeast to exchange plasmid-selectable markers. Biotechniques. 33: 978, 980, 982. PMID 12449370  1
2002 Greenall A, Hadcroft AP, Malakasi P, Jones N, Morgan BA, Hoffman CS, Whitehall SK. Role of fission yeast Tup1-like repressors and Prr1 transcription factor in response to salt stress. Molecular Biology of the Cell. 13: 2977-89. PMID 12221110 DOI: 10.1091/mbc.01-12-0568  1
2002 Ivey FD, Hoffman CS. Pseudostructural inhibitors of G protein signaling during development. Developmental Cell. 3: 154-5. PMID 12194845 DOI: 10.1016/S1534-5807(02)00232-0  1
2001 Hoffman CS. Preparation of yeast DNA. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit13.11. PMID 18265095 DOI: 10.1002/0471142727.mb1311s39  1
2001 Janoo RT, Neely LA, Braun BR, Whitehall SK, Hoffman CS. Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex. Genetics. 157: 1205-15. PMID 11238405  1
2001 Landry S, Hoffman CS. The git5 Gbeta and git11 Ggamma form an atypical Gbetagamma dimer acting in the fission yeast glucose/cAMP pathway. Genetics. 157: 1159-68. PMID 11238401  1
2000 Welton RM, Hoffman CS. Glucose monitoring in fission yeast via the Gpa2 galpha, the git5 Gbeta and the git3 putative glucose receptor. Genetics. 156: 513-21. PMID 11014802  1
2000 Neely LA, Hoffman CS. Protein kinase A and mitogen-activated protein kinase pathways antagonistically regulate fission yeast fbp1 transcription by employing different modes of action at two upstream activation sites. Molecular and Cellular Biology. 20: 6426-34. PMID 10938120 DOI: 10.1128/MCB.20.17.6426-6434.2000  1
2000 Landry S, Pettit MT, Apolinario E, Hoffman CS. The fission yeast git5 gene encodes a Gbeta subunit required for glucose-triggered adenylate cyclase activation. Genetics. 154: 1463-71. PMID 10747045  1
2000 Hoffman CS, Welton R. Mutagenesis and gene cloning in Schizosaccharomyces pombe using nonhomologous plasmid integration and rescue. Biotechniques. 28: 532-6, 538, 540. PMID 10723568  1
1996 Dal Santo P, Blanchard B, Hoffman CS. The Schizosaccharomyces pombe pyp1 protein tyrosine phosphatase negatively regulates nutrient monitoring pathways. Journal of Cell Science. 109: 1919-25. PMID 8832414  1
1995 Jin M, Fujita M, Culley BM, Apolinario E, Yamamoto M, Maundrell K, Hoffman CS. sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Genetics. 140: 457-67. PMID 7498728  1
1994 Nocero M, Isshiki T, Yamamoto M, Hoffman CS. Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8). Genetics. 138: 39-45. PMID 8001792  1
1993 Apolinario E, Nocero M, Jin M, Hoffman CS. Cloning and manipulation of the Schizosaccharomyces pombe his7+ gene as a new selectable marker for molecular genetic studies. Current Genetics. 24: 491-5. PMID 8299169 DOI: 10.1007/BF00351711  1
1992 Ottilie S, Chernoff J, Hannig G, Hoffman CS, Erikson RL. The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis. Molecular and Cellular Biology. 12: 5571-80. PMID 1448087  1
1991 Ottilie S, Chernoff J, Hannig G, Hoffman CS, Erikson RL. A fission-yeast gene encoding a protein with features of protein-tyrosine-phosphatases. Proceedings of the National Academy of Sciences of the United States of America. 88: 3455-9. PMID 1849659  1
1991 Hoffman CS, Winston F. Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. Genes & Development. 5: 561-71. PMID 1849107  1
1990 Hoffman CS, Winston F. Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe. Genetics. 124: 807-16. PMID 2157626  1
1989 Hoffman CS, Winston F. A transcriptionally regulated expression vector for the fission yeast Schizosaccharomyces pombe. Gene. 84: 473-9. PMID 2558974 DOI: 10.1016/0378-1119(89)90523-4  1
1987 Hoffman CS, Winston F. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene. 57: 267-72. PMID 3319781 DOI: 10.1016/0378-1119(87)90131-4  1
1985 Hoffman CS, Wright A. Fusions of secreted proteins to alkaline phosphatase: an approach for studying protein secretion. Proceedings of the National Academy of Sciences of the United States of America. 82: 5107-11. PMID 3860846  1
1985 Malamy MH, Rahaim PT, Hoffman CS, Baghdoyan D, O'Connor MB, Miller JF. A frameshift mutation at the junction of an IS1 insertion within lacZ restores beta-galactosidase activity via formation of an active lacZ-IS1 fusion protein. Journal of Molecular Biology. 181: 551-5. PMID 2987506 DOI: 10.1016/0022-2836(85)90427-9  1
1982 Truitt CL, Hoffman CS, Holt CE. A gene, alcA, affecting the life cycle from expressed in Physarum polycephalum Genetics. 101: 35-55.  1
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