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Michael B. Jarstfer - Publications

Affiliations: 
Medicinal Chemistry and Natural Products University of North Carolina, Chapel Hill, Chapel Hill, NC 
Website:
http://pharmacy.unc.edu/faculty-research/faculty-directory/michaeljarstfer
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Moy SS, Teng BL, Nikolova VD, Riddick NV, Simpson CD, Van Deusen A, Janzen WP, Sassano MF, Pedersen CA, Jarstfer MB. Prosocial effects of an oxytocin metabolite, but not synthetic oxytocin receptor agonists, in a mouse model of autism. Neuropharmacology. PMID 30399367 DOI: 10.1016/J.Neuropharm.2018.10.036  0.699
2015 Shirgahi Talari F, Bagherzadeh K, Golestanian S, Jarstfer M, Amanlou M. Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays. Journal of Chemical Information and Modeling. 55: 2596-610. PMID 26529120 DOI: 10.1021/acs.jcim.5b00336  0.338
2015 Shirgahi Talari F, Bagherzadeh K, Golestanian S, Jarstfer M, Amanlou M. Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays Journal of Chemical Information and Modeling. 55: 2596-2610. DOI: 10.1021/Acs.Jcim.5B00336  0.44
2014 Sekaran V, Soares J, Jarstfer MB. Telomere maintenance as a target for drug discovery. Journal of Medicinal Chemistry. 57: 521-38. PMID 24053596 DOI: 10.1021/Jm400528T  0.762
2014 Jarstfer MB, Shobair M, Wang Y. Solvent Kinetic Isotope Effects on 2'-Hydroxyl Acylation of RNA Biophysical Journal. 106: 2-5. DOI: 10.1016/J.Bpj.2013.11.1669  0.369
2012 Sassano MF, Schlesinger AP, Jarstfer MB. Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase. The Open Medicinal Chemistry Journal. 6: 20-8. PMID 23173022 DOI: 10.2174/1874104501206010020  0.786
2012 Cole DI, Legassie JD, Bonifacio LN, Sekaran VG, Ding F, Dokholyan NV, Jarstfer MB. New models of Tetrahymena telomerase RNA from experimentally derived constraints and modeling. Journal of the American Chemical Society. 134: 20070-80. PMID 23163801 DOI: 10.1021/Ja305636U  0.719
2012 Shobair M, Cole D, Ding F, Jarstfer M, Dokholyan N. Computational Modeling of Telomerase in Action Biophysical Journal. 102: 732a. DOI: 10.1016/J.Bpj.2011.11.3972  0.451
2011 Soares J, Keppler BR, Wang X, Lee KH, Jarstfer MB. ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. Bioorganic & Medicinal Chemistry Letters. 21: 7474-8. PMID 22044621 DOI: 10.1016/J.Bmcl.2011.09.112  0.765
2011 Soares J, Lowe MM, Jarstfer MB. The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate. Biochemistry. 50: 9046-55. PMID 21936563 DOI: 10.1021/Bi2010398  0.609
2010 Bonifacio LN, Jarstfer MB. MiRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts. Plos One. 5. PMID 20824140 DOI: 10.1371/Journal.Pone.0012519  0.733
2010 Moon IK, Jarstfer MB. Preparation of G-quartet structures and detection by native gel electrophoresis. Methods in Molecular Biology (Clifton, N.J.). 608: 51-63. PMID 20012415 DOI: 10.1007/978-1-59745-363-9_4  0.67
2010 Sekaran VG, Soares J, Jarstfer MB. Structures of telomerase subunits provide functional insights. Biochimica Et Biophysica Acta. 1804: 1190-201. PMID 19665593 DOI: 10.1016/J.Bbapap.2009.07.019  0.792
2009 Fu YT, Keppler BR, Soares J, Jarstfer MB. BRACO19 analog dimers with improved inhibition of telomerase and hPot 1. Bioorganic & Medicinal Chemistry. 17: 2030-7. PMID 19201200 DOI: 10.1016/J.Bmc.2009.01.015  0.809
2008 Bonifacio L, Church FC, Jarstfer MB. Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamer. International Journal of Molecular Sciences. 9: 422-33. PMID 19325759 DOI: 10.3390/Ijms9030422  0.775
2007 Bryan TM, Jarstfer MB. Interrogation of G-quadruplex-protein interactions. Methods (San Diego, Calif.). 43: 332-9. PMID 17967703 DOI: 10.1016/J.Ymeth.2007.05.001  0.698
2007 Moon IK, Jarstfer MB. The human telomere and its relationship to human disease, therapy, and tissue engineering. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4595-620. PMID 17485399 DOI: 10.2741/2412  0.662
2006 Legassie JD, Jarstfer MB. The unmasking of telomerase. Structure (London, England : 1993). 14: 1603-9. PMID 17098185 DOI: 10.1016/J.Str.2006.09.004  0.809
2006 Fouché N, Moon IK, Keppler BR, Griffith JD, Jarstfer MB. Electron microscopic visualization of telomerase from Euplotes aediculatus bound to a model telomere DNA. Biochemistry. 45: 9624-31. PMID 16878997 DOI: 10.1021/Bi060313S  0.802
2006 Chen Y, Fender J, Legassie JD, Jarstfer MB, Bryan TM, Varani G. Structure of stem-loop IV of Tetrahymena telomerase RNA. The Embo Journal. 25: 3156-66. PMID 16778765 DOI: 10.1038/Sj.Emboj.7601195  0.779
2006 Keppler BR, Grady AT, Jarstfer MB. The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity. The Journal of Biological Chemistry. 281: 19840-8. PMID 16714764 DOI: 10.1074/Jbc.M511067200  0.776
2006 Keppler BR, Jarstfer MB. A high-throughput assay for a human telomerase protein-human telomerase RNA interaction. Analytical Biochemistry. 353: 75-82. PMID 16620757 DOI: 10.1016/J.Ab.2006.03.027  0.767
2006 Oganesian L, Moon IK, Bryan TM, Jarstfer MB. Extension of G-quadruplex DNA by ciliate telomerase. The Embo Journal. 25: 1148-59. PMID 16511573 DOI: 10.1038/Sj.Emboj.7601006  0.769
2005 Legassie JD, Jarstfer MB. Telomerase as a DNA-dependent DNA polymerase. Biochemistry. 44: 14191-201. PMID 16245935 DOI: 10.1021/Bi050628S  0.797
2004 Dominick PK, Keppler BR, Legassie JD, Moon IK, Jarstfer MB. Nucleic acid-binding ligands identify new mechanisms to inhibit telomerase. Bioorganic & Medicinal Chemistry Letters. 14: 3467-71. PMID 15177454 DOI: 10.1016/J.Bmcl.2004.04.055  0.736
2004 Dominick PK, Jarstfer MB. A conformationally constrained nucleotide analogue controls the folding topology of a DNA g-quadruplex. Journal of the American Chemical Society. 126: 5050-1. PMID 15099071 DOI: 10.1021/Ja039192Z  0.429
2004 Keppler BR, Jarstfer MB. Inhibition of telomerase activity by preventing proper assemblage. Biochemistry. 43: 334-43. PMID 14717587 DOI: 10.1021/Bi035583E  0.78
2002 Jarstfer MB, Cech TR. Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation. Biochemistry. 41: 151-61. PMID 11772012 DOI: 10.1021/Bi011649Z  0.582
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