Grant W. Brown - Publications

Biochemistry University of Toronto, Toronto, ON, Canada 
DNA replication, DNA repair

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gallo D, Brown GW. Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer. Critical Reviews in Biochemistry and Molecular Biology. 1-32. PMID 31429594 DOI: 10.1080/10409238.2019.1651817  1
2019 Gallo D, Kim T, Szakal B, Saayman X, Narula A, Park Y, Branzei D, Zhang Z, Brown GW. Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates. Molecular Cell. PMID 30733119 DOI: 10.1016/j.molcel.2019.01.001  1
2018 Sing TL, Hung MP, Ohnuki S, Suzuki G, San Luis BJ, McClain M, Unruh JR, Yu Z, Ou J, Marshall-Sheppard J, Huh WK, Costanzo M, Boone C, Ohya Y, Jaspersen SL, ... Brown GW, et al. The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. The Journal of Cell Biology. PMID 29875260 DOI: 10.1083/jcb.201709009  1
2018 Díaz-Mejía JJ, Celaj A, Mellor JC, Coté A, Balint A, Ho B, Bansal P, Shaeri F, Gebbia M, Weile J, Verby M, Karkhanina A, Zhang Y, Wong C, Rich J, ... ... Brown GW, et al. Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Molecular Systems Biology. 14: e7985. PMID 29807908  1
2018 Becker JR, Gallo D, Leung W, Croissant T, Thu YM, Nguyen HD, Starr TK, Brown GW, Bielinsky AK. Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner. Nucleic Acids Research. PMID 29741650 DOI: 10.1093/nar/gky313  1
2018 Kuzmin E, VanderSluis B, Wang W, Tan G, Deshpande R, Chen Y, Usaj M, Balint A, Mattiazzi Usaj M, van Leeuwen J, Koch EN, Pons C, Dagilis AJ, Pryszlak M, Wang JZY, ... ... Brown GW, et al. Systematic analysis of complex genetic interactions. Science (New York, N.Y.). 360. PMID 29674565 DOI: 10.1126/science.aao1729  1
2018 Ho B, Baryshnikova A, Brown GW. Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome. Cell Systems. PMID 29361465 DOI: 10.1016/j.cels.2017.12.004  1
2017 Piotrowski JS, Li SC, Deshpande R, Simpkins SW, Nelson J, Yashiroda Y, Barber JM, Safizadeh H, Wilson E, Okada H, Gebre AA, Kubo K, Torres NP, LeBlanc MA, Andrusiak K, ... ... Brown GW, et al. Errata: Functional annotation of chemical libraries across diverse biological processes. Nature Chemical Biology. 13: 1286. PMID 29161247 DOI: 10.1038/nchembio1217-1286a  1
2017 Piotrowski JS, Li SC, Deshpande R, Simpkins SW, Nelson J, Yashiroda Y, Barber JM, Safizadeh H, Wilson E, Okada H, Gebre AA, Kubo K, Torres NP, LeBlanc MA, Andrusiak K, ... ... Brown GW, et al. Errata: Functional annotation of chemical libraries across diverse biological processes. Nature Chemical Biology. 13: 1286. PMID 29161244 DOI: 10.1038/nchembio1217-1286b  1
2017 Piotrowski JS, Li SC, Deshpande R, Simpkins SW, Nelson J, Yashiroda Y, Barber JM, Safizadeh H, Wilson E, Okada H, Gebre AA, Kubo K, Torres NP, LeBlanc MA, Andrusiak K, ... ... Brown GW, et al. Functional annotation of chemical libraries across diverse biological processes. Nature Chemical Biology. PMID 28759014 DOI: 10.1038/nchembio.2436  1
2017 Wheaton K, Campuzano D, Ma W, Sheinis M, Ho B, Brown GW, Benchimol S. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson Gilford Progeria Syndrome. Molecular and Cellular Biology. PMID 28483909 DOI: 10.1128/MCB.00659-16  1
2017 Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, ... ... Brown GW, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nature Communications. 8: 14432. PMID 28211448 DOI: 10.1038/ncomms14432  1
2016 Styles EB, Founk KJ, Zamparo LA, Sing TL, Altintas D, Ribeyre C, Ribaud V, Rougemont J, Mayhew D, Costanzo M, Usaj M, Verster AJ, Koch EN, Novarina D, Graf M, ... ... Brown GW, et al. Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Cell Systems. PMID 27617677 DOI: 10.1016/j.cels.2016.08.008  1
2016 Abraham KJ, Chan JN, Salvi JS, Ho B, Hall A, Vidya E, Guo R, Killackey SA, Liu N, Lee JE, Brown GW, Mekhail K. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids. Nucleic Acids Research. PMID 27574117 DOI: 10.1093/nar/gkw752  1
2016 Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Reports. PMID 27373152 DOI: 10.1016/j.celrep.2016.06.015  1
2016 Yimit A, Kim T, Anand R, Meister S, Ou J, Haber JE, Zhang Z, Brown GW. MTE1 Functions with MPH1 in Double-Strand Break Repair. Genetics. PMID 26920759 DOI: 10.1534/genetics.115.185454  1
2016 Torres NP, Ho B, Brown GW. High-throughput fluorescence microscopic analysis of protein abundance and localization in budding yeast. Critical Reviews in Biochemistry and Molecular Biology. 1-10. PMID 26893079 DOI: 10.3109/10409238.2016.1145185  1
2016 Gallo D, Wang G, Yip CM, Brown GW. Single-Molecule Analysis of Replicating Yeast Chromosomes. Cold Spring Harbor Protocols. 2016: pdb.top077784. PMID 26832692 DOI: 10.1101/pdb.top077784  1
2016 Gallo D, Wang G, Yip CM, Brown GW. Analysis of Replicating Yeast Chromosomes by DNA Combing. Cold Spring Harbor Protocols. 2016: pdb.prot085118. PMID 26832684 DOI: 10.1101/pdb.prot085118  1
2016 Tkáč J, Xu G, Adhikary H, Young JT, Gallo D, Escribano-Díaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, et al. HELB Is a Feedback Inhibitor of DNA End Resection. Molecular Cell. PMID 26774285 DOI: 10.1016/j.molcel.2015.12.013  1
2015 Dibitetto D, Ferrari M, Rawal CC, Balint A, Kim T, Zhang Z, Smolka MB, Brown GW, Marini F, Pellicioli A. Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks. Nucleic Acids Research. PMID 26490958 DOI: 10.1093/nar/gkv1080  1
2015 Jablonowski CM, Cussiol JR, Oberly S, Yimit A, Balint A, Kim T, Zhang Z, Brown GW, Smolka MB. Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase. Genetics. PMID 26362319 DOI: 10.1534/genetics.115.181479  1
2015 Yimit A, Riffle M, Brown GW. Genetic Regulation of Dna2 Localization During the DNA Damage Response. G3 (Bethesda, Md.). 5: 1937-44. PMID 26163422 DOI: 10.1534/g3.115.019208  1
2015 Balint A, Kim T, Gallo D, Cussiol JR, Bastos de Oliveira FM, Yimit A, Ou J, Nakato R, Gurevich A, Shirahige K, Smolka MB, Zhang Z, Brown GW. Assembly of Slx4 signaling complexes behind DNA replication forks. The Embo Journal. PMID 26113155 DOI: 10.15252/embj.201591190  1
2015 Chaillot J, Tebbji F, Remmal A, Boone C, Brown GW, Bellaoui M, Sellam A. The monoterpene carvacrol generates endoplasmic reticulum stress in the pathogenic fungus Candida albicans. Antimicrobial Agents and Chemotherapy. PMID 26014932 DOI: 10.1128/AAC.00551-15  1
2015 Torres NP, Brown GW. A high-throughput confocal fluorescence microscopy platform to study DNA replication stress in yeast cells. Methods in Molecular Biology (Clifton, N.J.). 1300: 1-12. PMID 25916702 DOI: 10.1007/978-1-4939-2596-4_1  1
2015 Cussiol JR, Jablonowski CM, Yimit A, Brown GW, Smolka MB. Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. The Embo Journal. 34: 1704-17. PMID 25896509 DOI: 10.15252/embj.201490834  1
2015 Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9. PMID 25843717 DOI: 10.1016/j.celrep.2015.03.019  1
2015 Hendry JA, Tan G, Ou J, Boone C, Brown GW. Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda, Md.). 5: 997-1006. PMID 25721128 DOI: 10.1534/g3.115.016576  1
2014 Larin M, Gallo D, Tamblyn L, Yang J, Liao H, Sabat N, Brown GW, McPherson JP. Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair. Nucleic Acids Research. 42: 9807-20. PMID 25056314 DOI: 10.1093/nar/gku676  1
2014 Coschi CH, Ishak CA, Gallo D, Marshall A, Talluri S, Wang J, Cecchini MJ, Martens AL, Percy V, Welch I, Boutros PC, Brown GW, Dick FA. Haploinsufficiency of an RB-E2F1-Condensin II complex leads to aberrant replication and aneuploidy. Cancer Discovery. 4: 840-53. PMID 24740996 DOI: 10.1158/2159-8290.CD-14-0215  1
2014 Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, ... ... Brown GW, et al. Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (New York, N.Y.). 344: 208-11. PMID 24723613 DOI: 10.1126/science.1250217  1
2014 Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L. A role for USP7 in DNA replication. Molecular and Cellular Biology. 34: 132-45. PMID 24190967 DOI: 10.1128/MCB.00639-13  1
2013 Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D, Qian Y, Martindale JL, Piao Y, Machamer J, ... ... Brown GW, et al. Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nature Neuroscience. 16: 1238-47. PMID 23912945 DOI: 10.1038/nn.3479  1
2013 Torres NP, Lee AY, Giaever G, Nislow C, Brown GW. A high-throughput yeast assay identifies synergistic drug combinations. Assay and Drug Development Technologies. 11: 299-307. PMID 23772551 DOI: 10.1089/adt.2012.503  1
2013 Srikumar T, Lewicki MC, Costanzo M, Tkach JM, van Bakel H, Tsui K, Johnson ES, Brown GW, Andrews BJ, Boone C, Giaever G, Nislow C, Raught B. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. The Journal of Cell Biology. 201: 145-63. PMID 23547032 DOI: 10.1083/jcb.201210019  1
2012 Chambers AL, Ormerod G, Durley SC, Sing TL, Brown GW, Kent NA, Downs JA. The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes & Development. 26: 2590-603. PMID 23207916 DOI: 10.1101/gad.199976.112  1
2012 Cheung-Ong K, Song KT, Ma Z, Shabtai D, Lee AY, Gallo D, Heisler LE, Brown GW, Bierbach U, Giaever G, Nislow C. Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents. Acs Chemical Biology. 7: 1892-901. PMID 22928710 DOI: 10.1021/cb300320d  1
2012 Yang J, Bachrati CZ, Hickson ID, Brown GW. BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity. Plos One. 7: e41208. PMID 22911760 DOI: 10.1371/journal.pone.0041208  1
2012 Tkach JM, Yimit A, Lee AY, Riffle M, Costanzo M, Jaschob D, Hendry JA, Ou J, Moffat J, Boone C, Davis TN, Nislow C, Brown GW. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nature Cell Biology. 14: 966-76. PMID 22842922 DOI: 10.1038/ncb2549  1
2012 Cheng E, Vaisica JA, Ou J, Baryshnikova A, Lu Y, Roth FP, Brown GW. Genome rearrangements caused by depletion of essential DNA replication proteins in Saccharomyces cerevisiae. Genetics. 192: 147-60. PMID 22673806 DOI: 10.1534/genetics.112.141051  1
2012 Yang J, O'Donnell L, Durocher D, Brown GW. RMI1 promotes DNA replication fork progression and recovery from replication fork stress. Molecular and Cellular Biology. 32: 3054-64. PMID 22645306 DOI: 10.1128/MCB.00255-12  1
2012 Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou J, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW. Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. The Embo Journal. 31: 895-907. PMID 22234187 DOI: 10.1038/emboj.2011.485  1
2011 Bendaha H, Yu L, Touzani R, Souane R, Giaever G, Nislow C, Boone C, El Kadiri S, Brown GW, Bellaoui M. New azole antifungal agents with novel modes of action: synthesis and biological studies of new tridentate ligands based on pyrazole and triazole. European Journal of Medicinal Chemistry. 46: 4117-24. PMID 21723647 DOI: 10.1016/j.ejmech.2011.06.012  1
2011 Bellay J, Atluri G, Sing TL, Toufighi K, Costanzo M, Ribeiro PS, Pandey G, Baller J, VanderSluis B, Michaut M, Han S, Kim P, Brown GW, Andrews BJ, Boone C, et al. Putting genetic interactions in context through a global modular decomposition. Genome Research. 21: 1375-87. PMID 21715556 DOI: 10.1101/gr.117176.110  1
2011 Vaisica JA, Baryshnikova A, Costanzo M, Boone C, Brown GW. Mms1 and Mms22 stabilize the replisome during replication stress. Molecular Biology of the Cell. 22: 2396-408. PMID 21593207 DOI: 10.1091/mbc.E10-10-0848  1
2011 Qaddouri B, Guaadaoui A, Bellirou A, Hamal A, Melhaoui A, Brown GW, Bellaoui M. The Budding Yeast "Saccharomyces cerevisiae" as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 954140. PMID 19596744 DOI: 10.1093/ecam/nep069  1
2011 Whitney J, Koh J, Costanzo M, Brown G, Boone C, Brudno M. Clustering with overlap for genetic interaction networks via local search optimization Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6833: 326-338. DOI: 10.1007/978-3-642-23038-7_27  1
2010 Baryshnikova A, Costanzo M, Kim Y, Ding H, Koh J, Toufighi K, Youn JY, Ou J, San Luis BJ, Bandyopadhyay S, Hibbs M, Hess D, Gingras AC, Bader GD, Troyanskaya OG, ... Brown GW, et al. Quantitative analysis of fitness and genetic interactions in yeast on a genome scale. Nature Methods. 7: 1017-24. PMID 21076421 DOI: 10.1038/nmeth.1534  1
2010 O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, ... ... Brown GW, et al. The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Molecular Cell. 40: 619-31. PMID 21055983 DOI: 10.1016/j.molcel.2010.10.024  1
2010 Berbenetz NM, Nislow C, Brown GW. Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure. Plos Genetics. 6: e1001092. PMID 20824081 DOI: 10.1371/journal.pgen.1001092  1
2010 Yang J, Bachrati CZ, Ou J, Hickson ID, Brown GW. Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1. The Journal of Biological Chemistry. 285: 21426-36. PMID 20445207 DOI: 10.1074/jbc.M110.123216  1
2009 Dion B, Brown GW. Comparative genome hybridization on tiling microarrays to detect aneuploidies in yeast. Methods in Molecular Biology (Clifton, N.J.). 548: 1-18. PMID 19521816 DOI: 10.1007/978-1-59745-540-4_1  1
2009 Davidson MB, Brown GW. Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae. Dna Repair. 8: 1110-7. PMID 19464964 DOI: 10.1016/j.dnarep.2009.03.010  1
2008 Yu L, Lopez A, Anaflous A, El Bali B, Hamal A, Ericson E, Heisler LE, McQuibban A, Giaever G, Nislow C, Boone C, Brown GW, Bellaoui M. Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. Plos Genetics. 4: e1000284. PMID 19043571 DOI: 10.1371/journal.pgen.1000284  1
2008 Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/science.1162790  1
2008 Xu D, Guo R, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W. RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes & Development. 22: 2843-55. PMID 18923082 DOI: 10.1101/gad.1708608  1
2008 Davidson MB, Brown GW. The N- and C-termini of Elg1 contribute to the maintenance of genome stability. Dna Repair. 7: 1221-32. PMID 18482875 DOI: 10.1016/j.dnarep.2008.04.001  1
2008 Duro E, Vaisica JA, Brown GW, Rouse J. Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. Dna Repair. 7: 811-8. PMID 18321796 DOI: 10.1016/j.dnarep.2008.01.007  1
2008 Roberts TM, Zaidi IW, Vaisica JA, Peter M, Brown GW. Regulation of rtt107 recruitment to stalled DNA replication forks by the cullin rtt101 and the rtt109 acetyltransferase. Molecular Biology of the Cell. 19: 171-80. PMID 17978089 DOI: 10.1091/mbc.E07-09-0961  1
2007 Xu H, Boone C, Brown GW. Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics. 176: 1417-29. PMID 17483413 DOI: 10.1534/genetics.107.072876  1
2007 Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Brown GW, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/nature05649  1
2006 Yu L, Peña Castillo L, Mnaimneh S, Hughes TR, Brown GW. A survey of essential gene function in the yeast cell division cycle. Molecular Biology of the Cell. 17: 4736-47. PMID 16943325 DOI: 10.1091/mbc.E06-04-0368  1
2006 Chang M, Parsons AB, Sheikh BH, Boone C, Brown GW. Genomic approaches for identifying DNA damage response pathways in S. cerevisiae. Methods in Enzymology. 409: 213-35. PMID 16793404 DOI: 10.1016/S0076-6879(05)09013-0  1
2006 Wu L, Bachrati CZ, Ou J, Xu C, Yin J, Chang M, Wang W, Li L, Brown GW, Hickson ID. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proceedings of the National Academy of Sciences of the United States of America. 103: 4068-73. PMID 16537486 DOI: 10.1073/pnas.0508295103  1
2006 Zhang C, Roberts TM, Yang J, Desai R, Brown GW. Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae. Dna Repair. 5: 336-46. PMID 16325482 DOI: 10.1016/j.dnarep.2005.10.010  1
2006 Roberts TM, Kobor MS, Bastin-Shanower SA, Ii M, Horte SA, Gin JW, Emili A, Rine J, Brill SJ, Brown GW. Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Molecular Biology of the Cell. 17: 539-48. PMID 16267268 DOI: 10.1091/mbc.E05-08-0785  1
2005 Davierwala AP, Haynes J, Li Z, Brost RL, Robinson MD, Yu L, Mnaimneh S, Ding H, Zhu H, Chen Y, Cheng X, Brown GW, Boone C, Andrews BJ, Hughes TR. The synthetic genetic interaction spectrum of essential genes. Nature Genetics. 37: 1147-52. PMID 16155567 DOI: 10.1038/ng1640  1
2005 Chang M, Bellaoui M, Zhang C, Desai R, Morozov P, Delgado-Cruzata L, Rothstein R, Freyer GA, Boone C, Brown GW. RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. The Embo Journal. 24: 2024-33. PMID 15889139 DOI: 10.1038/sj.emboj.7600684  1
2004 Suter B, Tong A, Chang M, Yu L, Brown GW, Boone C, Rine J. The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae. Genetics. 167: 579-91. PMID 15238513 DOI: 10.1534/genetics.103.024851  1
2004 Tong AH, Lesage G, Bader GD, Ding H, Xu H, Xin X, Young J, Berriz GF, Brost RL, Chang M, Chen Y, Cheng X, Chua G, Friesen H, Goldberg DS, ... ... Brown GW, et al. Global mapping of the yeast genetic interaction network. Science (New York, N.Y.). 303: 808-13. PMID 14764870 DOI: 10.1126/science.1091317  1
2004 Mayer ML, Pot I, Chang M, Xu H, Aneliunas V, Kwok T, Newitt R, Aebersold R, Boone C, Brown GW, Hieter P. Identification of protein complexes required for efficient sister chromatid cohesion. Molecular Biology of the Cell. 15: 1736-45. PMID 14742714 DOI: 10.1091/mbc.E03-08-0619  1
2004 Parsons AB, Brost RL, Ding H, Li Z, Zhang C, Sheikh B, Brown GW, Kane PM, Hughes TR, Boone C. Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nature Biotechnology. 22: 62-9. PMID 14661025 DOI: 10.1038/nbt919  1
2003 Duncker BP, Brown GW. Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts. Mutation Research. 532: 21-7. PMID 14643426 DOI: 10.1016/j.mrfmmm.2003.08.007  1
2003 Bellaoui M, Chang M, Ou J, Xu H, Boone C, Brown GW. Elg1 forms an alternative RFC complex important for DNA replication and genome integrity. The Embo Journal. 22: 4304-13. PMID 12912927 DOI: 10.1093/emboj/cdg406  1
2002 Chang M, Bellaoui M, Boone C, Brown GW. A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 99: 16934-9. PMID 12482937 DOI: 10.1073/pnas.262669299  1
2002 Fung AD, Ou J, Bueler S, Brown GW. A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase. Molecular and Cellular Biology. 22: 4477-90. PMID 12052858 DOI: 10.1128/MCB.22.13.4477-4490.2002  1
2000 Snaith HA, Brown GW, Forsburg SL. Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Molecular and Cellular Biology. 20: 7922-32. PMID 11027263 DOI: 10.1128/MCB.20.21.7922-7932.2000  1
2000 Kelly TJ, Brown GW. Regulation of chromosome replication. Annual Review of Biochemistry. 69: 829-80. PMID 10966477 DOI: 10.1146/annurev.biochem.69.1.829  1
1999 Brown GW, Kelly TJ. Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 8443-8. PMID 10411894 DOI: 10.1073/pnas.96.15.8443  1
1998 Brown GW, Kelly TJ. Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast. The Journal of Biological Chemistry. 273: 22083-90. PMID 9705352 DOI: 10.1074/jbc.273.34.22083  1
1997 Jallepalli PV, Brown GW, Muzi-Falconi M, Tien D, Kelly TJ. Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation. Genes & Development. 11: 2767-79. PMID 9353247  1
1997 Brown GW, Jallepalli PV, Huneycutt BJ, Kelly TJ. Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 94: 6142-7. PMID 9177184 DOI: 10.1073/pnas.94.12.6142  1
1996 Muzi-Falconi M, Brown GW, Kelly TJ. Controlling initiation during the cell cycle. DNA replication. Current Biology : Cb. 6: 229-33. PMID 8805233  1
1996 Muzi Falconi M, Brown GW, Kelly TJ. cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America. 93: 1566-70. PMID 8643672 DOI: 10.1073/pnas.93.4.1566  1
1994 Brown GW, Hines JC, Fisher P, Ray DS. Isolation of the genes encoding the 51-kilodalton and 28-kilodalton subunits of Crithidia fasciculata replication protein A Molecular and Biochemical Parasitology. 63: 135-142. PMID 8183313 DOI: 10.1016/0166-6851(94)90016-7  1
1994 Pasion SG, Brown GW, Brown LM, Ray DS. Periodic expression of nuclear and mitochondrial DNA replication genes during the trypanosomatid cell cycle. Journal of Cell Science. 107: 3515-20. PMID 7706402  1
1993 Brown GW, Melendy T, Ray DS. Replication protein A from the trypanosomatid Crithidia fasciculata is inactive in the primosome assembly step of SV40 DNA replication Molecular and Biochemical Parasitology. 59: 323-325. PMID 8393527 DOI: 10.1016/0166-6851(93)90230-U  1
1992 Brown GW, Ray DS. Purification and characterization of DNA ligase I from the trypanosomatid Crithidia fasciculata Nucleic Acids Research. 20: 3905-3910. PMID 1508676  1
1992 Brown GW, Melendy TE, Ray DS. Conservation of structure and function of DNA replication protein A in the trypanosomatid Crithidia fasciculata. Proceedings of the National Academy of Sciences of the United States of America. 89: 10227-31. PMID 1332038  1
1991 Yeung DE, Brown GW, Tam P, Russnak RH, Wilson G, Clark-Lewis I, Astell CR. Monoclonal antibodies to the major nonstructural nuclear protein of minute virus of mice Virology. 181: 35-45. PMID 1825254 DOI: 10.1016/0042-6822(91)90467-P  1
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