| Year |
Citation |
Score |
| 2024 |
Kashyap SN, Fox SN, Wilson KI, Murchison CF, Ambaw YA, Walther TC, Farese RV, Arrant AE, Roberson ED. Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia. Biorxiv : the Preprint Server For Biology. PMID 39345608 DOI: 10.1101/2024.09.15.613118 |
0.676 |
|
| 2024 |
Singh S, Dransfeld U, Ambaw Y, Lopez-Scarim J, Farese RV, Walther TC. PLD3 and PLD4 synthesize -BMP, a key phospholipid enabling lipid degradation in lysosomes. Biorxiv : the Preprint Server For Biology. PMID 38562702 DOI: 10.1101/2024.03.21.586175 |
0.723 |
|
| 2023 |
Chitraju C, Fischer AW, Ambaw YA, Wang K, Yuan B, Hui S, Walther TC, Farese RV. Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity. Elife. 12. PMID 37782317 DOI: 10.7554/eLife.88049 |
0.707 |
|
| 2023 |
Chung J, Park J, Lai ZW, Lambert TJ, Richards RC, Zhang J, Walther TC, Farese RV. The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets. Nature Cell Biology. PMID 37443287 DOI: 10.1038/s41556-023-01178-w |
0.742 |
|
| 2023 |
Wang K, Lee CW, Sui X, Kim S, Wang S, Higgs AB, Baublis AJ, Voth GA, Liao M, Walther TC, Farese RV. The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification. Nature Communications. 14: 3533. PMID 37316513 DOI: 10.1038/s41467-023-38932-5 |
0.713 |
|
| 2023 |
Sui X, Wang K, Song K, Xu C, Song J, Lee CW, Liao M, Farese RV, Walther TC. Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis. Nature Communications. 14: 3100. PMID 37248213 DOI: 10.1038/s41467-023-38934-3 |
0.698 |
|
| 2023 |
Walther TC, Kim S, Arlt H, Voth GA, Farese RV. Structure and function of lipid droplet assembly complexes. Current Opinion in Structural Biology. 80: 102606. PMID 37150040 DOI: 10.1016/j.sbi.2023.102606 |
0.759 |
|
| 2023 |
Bond LM, Ibrahim A, Lai ZW, Walzem RL, Bronson RT, Ilkayeva OR, Walther TC, Farese RV. Fitm2 is required for ER homeostasis and normal function of murine liver. The Journal of Biological Chemistry. 103022. PMID 36805337 DOI: 10.1016/j.jbc.2023.103022 |
0.717 |
|
| 2022 |
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, ... ... Farese RV, et al. Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nature Communications. 13: 5924. PMID 36207292 DOI: 10.1038/s41467-022-33500-9 |
0.745 |
|
| 2022 |
Farese RV, Walther TC. Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum. Cold Spring Harbor Perspectives in Biology. PMID 36096640 DOI: 10.1101/cshperspect.a041246 |
0.744 |
|
| 2022 |
Song J, Mizrak A, Lee CW, Cicconet M, Lai ZW, Tang WC, Lu CH, Mohr SE, Farese RV, Walther TC. Identification of two pathways mediating protein targeting from ER to lipid droplets. Nature Cell Biology. PMID 36050470 DOI: 10.1038/s41556-022-00974-0 |
0.738 |
|
| 2022 |
Kim S, Chung J, Arlt H, Pak AJ, Farese RV, Walther TC, Voth GA. Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane. Elife. 11. PMID 35583926 DOI: 10.7554/eLife.75808 |
0.73 |
|
| 2022 |
Arlt H, Sui X, Folger B, Adams C, Chen X, Remme R, Hamprecht FA, DiMaio F, Liao M, Goodman JM, Farese RV, Walther TC. Seipin forms a flexible cage at lipid droplet formation sites. Nature Structural & Molecular Biology. PMID 35210614 DOI: 10.1038/s41594-021-00718-y |
0.708 |
|
| 2022 |
Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer N, Song J, Kuruvilla L, Chitraju C, Boland S, Jang DK, von Grotthuss M, Costanzo MC, Rydén M, Olzmann JA, Flannick J, Burtt NP, ... Farese RV, et al. The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology. Developmental Cell. 57: 387-397.e4. PMID 35134345 DOI: 10.1016/j.devcel.2022.01.003 |
0.762 |
|
| 2022 |
Kim S, Li C, Farese RV, Walther TC, Voth GA. Key Factors Governing Initial Stages of Lipid Droplet Formation. The Journal of Physical Chemistry. B. PMID 34990551 DOI: 10.1021/acs.jpcb.1c09683 |
0.735 |
|
| 2021 |
Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, ... ... Farese RV, et al. Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues. Nature. PMID 34732896 DOI: 10.1038/s41586-021-04132-8 |
0.644 |
|
| 2021 |
Xu CS, Pang S, Shtengel G, Müller A, Ritter AT, Hoffman HK, Takemura SY, Lu Z, Pasolli HA, Iyer N, Chung J, Bennett D, Weigel AV, Freeman M, van Engelenburg SB, ... ... Farese RV, et al. An open-access volume electron microscopy atlas of whole cells and tissues. Nature. PMID 34616045 DOI: 10.1038/s41586-021-03992-4 |
0.665 |
|
| 2021 |
Olarte MJ, Swanson JMJ, Walther TC, Farese RV. The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting. Trends in Biochemical Sciences. PMID 34583871 DOI: 10.1016/j.tibs.2021.08.007 |
0.757 |
|
| 2021 |
Kumar S, Chitraju C, Farese R, Walther T, Burd CG. Conditional targeting of phosphatidylserine decarboxylase to lipid droplets. Biology Open. PMID 33593792 DOI: 10.1242/bio.058516 |
0.766 |
|
| 2021 |
Farese RV, Walther TC. The power of two: lessons from a scientific partnership. The Journal of Clinical Investigation. 131. PMID 33463550 DOI: 10.1172/JCI145966 |
0.619 |
|
| 2020 |
Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai ZW, Farese RV, Walther TC. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Reports. 33: 108378. PMID 33176155 DOI: 10.1016/j.celrep.2020.108378 |
0.694 |
|
| 2020 |
Chitraju C, Fischer AW, Farese RV, Walther TC. Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis. Cell Reports. 33: 108348. PMID 33147469 DOI: 10.1016/j.celrep.2020.108348 |
0.716 |
|
| 2020 |
Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. The Journal of Cell Biology. 219. PMID 32915949 DOI: 10.1083/Jcb.202006111 |
0.766 |
|
| 2020 |
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, ... Farese RV, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7 |
0.667 |
|
| 2020 |
Olarte MJ, Kim S, Sharp ME, Swanson JMJ, Farese RV, Walther TC. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting. Developmental Cell. PMID 32730754 DOI: 10.1016/J.Devcel.2020.07.001 |
0.741 |
|
| 2020 |
Sui X, Wang K, Gluchowski NL, Elliott SD, Liao M, Walther TC, Farese RV. Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature. 581: 323-328. PMID 32433611 DOI: 10.1038/S41586-020-2289-6 |
0.731 |
|
| 2020 |
Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant mice, a model of motor neuron degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345721 DOI: 10.1073/Pnas.1913956117 |
0.705 |
|
| 2020 |
Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Molecular Cell. PMID 32023484 DOI: 10.1016/J.Molcel.2020.01.014 |
0.744 |
|
| 2019 |
Chung J, Wu X, Lambert TJ, Lai ZW, Walther TC, Farese RV. LDAF1 and Seipin Form a Lipid Droplet Assembly Complex. Developmental Cell. PMID 31708432 DOI: 10.1016/J.Devcel.2019.10.006 |
0.738 |
|
| 2019 |
Walther TC, Farese RV. Un-phased: Lipid Droplets Modulate the Bioavailability of Antibiotics. Developmental Cell. 50: 530-532. PMID 31505174 DOI: 10.1016/J.Devcel.2019.08.009 |
0.7 |
|
| 2019 |
Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV, Walther TC. Hepatocyte Deletion of Triglyceride-Synthesis Enzyme DGAT2 Reduces Steatosis without Increasing Inflammation or Fibrosis. Hepatology (Baltimore, Md.). PMID 31081165 DOI: 10.1002/Hep.30765 |
0.72 |
|
| 2019 |
Chitraju C, Walther TC, Farese RV. The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes. Journal of Lipid Research. 60: 1112-1120. PMID 30936184 DOI: 10.1194/Jlr.M093112 |
0.701 |
|
| 2019 |
Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, ... Farese RV, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/J.Molcel.2019.01.036 |
0.722 |
|
| 2018 |
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, ... ... Farese RV, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028 |
0.72 |
|
| 2018 |
Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV, Walther TC. Cryo-electron microscopy structure of the lipid droplet-formation protein seipin. The Journal of Cell Biology. PMID 30327422 DOI: 10.1083/Jcb.201809067 |
0.757 |
|
| 2018 |
Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV. Progranulin in the hematopoietic compartment protects mice from atherosclerosis. Atherosclerosis. 277: 145-154. PMID 30212683 DOI: 10.1016/J.Atherosclerosis.2018.08.042 |
0.717 |
|
| 2018 |
Jayson CBK, Arlt H, Fischer AW, Lai ZW, Farese RV, Walther TC. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Molecular Biology of the Cell. mbcE18050282. PMID 29949452 DOI: 10.1091/Mbc.E18-05-0282 |
0.747 |
|
| 2018 |
Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511098 DOI: 10.1073/Pnas.1722344115 |
0.727 |
|
| 2018 |
Li Z, Lai ZW, Christiano R, Gazos-Lopes F, Walther TC, Farese RV. Global Analyses of Selective Insulin Resistance in Hepatocytes due to Palmitate Lipotoxicity. Molecular & Cellular Proteomics : McP. PMID 29414761 DOI: 10.1074/Mcp.Ra117.000560 |
0.664 |
|
| 2018 |
Prévost C, Sharp ME, Kory N, Lin Q, Voth GA, Farese RV, Walther TC. Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets. Developmental Cell. 44: 73-86.e4. PMID 29316443 DOI: 10.1016/J.Devcel.2017.12.011 |
0.752 |
|
| 2017 |
Inloes JM, Kiosses WB, Wang H, Walther TC, Farese RV, Cravatt BF. Functional Contribution of the Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2 to the Formation and Content of Lipid Droplets. Biochemistry. PMID 29278326 DOI: 10.1021/Acs.Biochem.7B01028 |
0.75 |
|
| 2017 |
Walther TC, Chung J, Farese RV. Lipid Droplet Biogenesis. Annual Review of Cell and Developmental Biology. PMID 28793795 DOI: 10.1146/Annurev-Cellbio-100616-060608 |
0.761 |
|
| 2017 |
Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV. Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis. Cell Metabolism. 26: 407-418.e3. PMID 28768178 DOI: 10.1016/J.Cmet.2017.07.012 |
0.721 |
|
| 2017 |
Gluchowski NL, Becuwe M, Walther TC, Farese RV. Lipid droplets and liver disease: from basic biology to clinical implications. Nature Reviews. Gastroenterology & Hepatology. 14: 343-355. PMID 28428634 DOI: 10.1038/Nrgastro.2017.32 |
0.745 |
|
| 2017 |
Gluchowski NL, Chitraju C, Picoraro JA, Mejhert N, Pinto S, Xin W, Kamin DS, Winter HS, Chung WK, Walther TC, Farese RV. Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea. Journal of Lipid Research. PMID 28373485 DOI: 10.1194/Jlr.P075119 |
0.69 |
|
| 2016 |
Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Fröhlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV, Walther TC. Mice Lacking Lipid Droplet-Associated Hydrolase, a Gene Linked to Human Prostate Cancer, Have Normal Cholesterol Ester Metabolism. Journal of Lipid Research. PMID 27836991 DOI: 10.1194/Jlr.M072538 |
0.746 |
|
| 2016 |
Fröhlich F, Olson DK, Christiano R, Farese RV, Walther TC. Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion. Proteomics. 16: 2759-2763. PMID 27717283 DOI: 10.1002/Pmic.201600269 |
0.723 |
|
| 2016 |
Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Farese RV, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 5. PMID 27564575 DOI: 10.7554/Elife.16582 |
0.767 |
|
| 2016 |
Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets. Trends in Cell Biology. 26: 535-546. PMID 26995697 DOI: 10.1016/J.Tcb.2016.02.007 |
0.746 |
|
| 2016 |
Farese RV, Walther TC. Lipid droplets go nuclear. The Journal of Cell Biology. 212: 7-8. PMID 26728852 DOI: 10.1083/Jcb.201512056 |
0.729 |
|
| 2016 |
Kory N, Farese RV, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets Trends in Cell Biology. 26: 535-546. DOI: 10.1016/j.tcb.2016.02.007 |
0.763 |
|
| 2016 |
Taniguchi C, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley L, Kahn C. Divergent Regulation of Hepatic Glucose and Lipid Metabolism by Phosphoinositide 3-Kinase via Akt and PKCλ/ζ Cell Metabolism. 23: 386. DOI: 10.1016/J.Cmet.2016.01.016 |
0.363 |
|
| 2015 |
Fröhlich F, Petit C, Kory N, Christiano R, Hannibal-Bach HK, Graham M, Liu X, Ejsing CS, Farese RV, Walther TC. The GARP complex is required for cellular sphingolipid homeostasis. Elife. 4. PMID 26357016 DOI: 10.7554/Elife.08712 |
0.723 |
|
| 2015 |
Kory N, Thiam AR, Farese RV, Walther TC. Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Developmental Cell. 34: 351-63. PMID 26212136 DOI: 10.1016/J.Devcel.2015.06.007 |
0.742 |
|
| 2015 |
Olson DK, Fröhlich F, Farese RV, Walther TC. Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. DOI: 10.1016/j.bbalip.2015.12.021 |
0.675 |
|
| 2014 |
Currie E, Guo X, Christiano R, Chitraju C, Kory N, Harrison K, Haas J, Walther TC, Farese RV. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. Journal of Lipid Research. 55: 1465-1477. PMID 24868093 DOI: 10.1194/Jlr.M050229 |
0.74 |
|
| 2014 |
Wilfling F, Haas JT, Walther TC, Farese RV. Lipid droplet biogenesis. Current Opinion in Cell Biology. 29: 39-45. PMID 24736091 DOI: 10.1016/J.Ceb.2014.03.008 |
0.758 |
|
| 2014 |
Wilfling F, Thiam AR, Olarte MJ, Wang J, Beck R, Gould TJ, Allgeyer ES, Pincet F, Bewersdorf J, Farese RV, Walther TC. Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting. Elife. 3: e01607. PMID 24497546 DOI: 10.7554/Elife.01607 |
0.776 |
|
| 2013 |
Thiam AR, Farese RV, Walther TC. The biophysics and cell biology of lipid droplets. Nature Reviews. Molecular Cell Biology. 14: 775-86. PMID 24220094 DOI: 10.1038/Nrm3699 |
0.756 |
|
| 2013 |
Nguyen AD, Nguyen TA, Martens LH, Mitic LL, Farese RV. Progranulin: at the interface of neurodegenerative and metabolic diseases. Trends in Endocrinology and Metabolism: Tem. 24: 597-606. PMID 24035620 DOI: 10.1016/j.tem.2013.08.003 |
0.474 |
|
| 2013 |
Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R, Simons K, Krogan NJ, Ernst R. A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Molecular Cell. 51: 519-30. PMID 23891562 DOI: 10.1016/J.Molcel.2013.06.014 |
0.485 |
|
| 2013 |
Currie E, Schulze A, Zechner R, Walther TC, Farese RV. Cellular fatty acid metabolism and cancer. Cell Metabolism. 18: 153-61. PMID 23791484 DOI: 10.1016/J.Cmet.2013.05.017 |
0.704 |
|
| 2013 |
Krahmer N, Farese RV, Walther TC. Balancing the fat: Lipid droplets and human disease Embo Molecular Medicine. 5: 905-915. PMID 23740690 DOI: 10.1002/Emmm.201100671 |
0.758 |
|
| 2013 |
Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Blackstone C, et al. A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Reports. 3: 1465-75. PMID 23684613 DOI: 10.1016/J.Celrep.2013.04.015 |
0.314 |
|
| 2013 |
Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV, et al. Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. Developmental Cell. 24: 384-99. PMID 23415954 DOI: 10.1016/J.Devcel.2013.01.013 |
0.75 |
|
| 2013 |
Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/Jbc.M112.441949 |
0.74 |
|
| 2013 |
Krahmer N, Hilger M, Kory N, Wilfling F, Stoehr G, Mann M, Farese RV, Walther TC. Protein correlation profiles identify lipid droplet proteins with high confidence. Molecular & Cellular Proteomics : McP. 12: 1115-26. PMID 23319140 DOI: 10.1074/Mcp.M112.020230 |
0.738 |
|
| 2012 |
Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV. DGAT1 mutation is linked to a congenital diarrheal disorder. The Journal of Clinical Investigation. 122: 4680-4. PMID 23114594 DOI: 10.1172/Jci64873 |
0.669 |
|
| 2012 |
Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV, Mak HY. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. The Journal of Cell Biology. 198: 895-911. PMID 22927462 DOI: 10.1083/jcb.201201139 |
0.368 |
|
| 2012 |
Farese RV, Zechner R, Newgard CB, Walther TC. The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance Cell Metabolism. 15: 570-573. PMID 22560209 DOI: 10.1016/J.Cmet.2012.03.004 |
0.648 |
|
| 2012 |
Walther TC, Farese RV. Lipid droplets and cellular lipid metabolism Annual Review of Biochemistry. 81: 687-714. PMID 22524315 DOI: 10.1146/Annurev-Biochem-061009-102430 |
0.768 |
|
| 2011 |
Krahmer N, Guo Y, Wilfling F, Hilger M, Lingrell S, Heger K, Newman HW, Schmidt-Supprian M, Vance DE, Mann M, Farese RV, Walther TC. Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. Cell Metabolism. 14: 504-15. PMID 21982710 DOI: 10.1016/J.Cmet.2011.07.013 |
0.748 |
|
| 2011 |
Bewersdorf J, Farese RV, Walther TC. A new way to look at fat Nature Methods. 8: 132-133. PMID 21278725 DOI: 10.1038/Nmeth0211-132 |
0.687 |
|
| 2009 |
Krahmer N, Guo Y, Farese RV, Walther TC. SnapShot: Lipid Droplets Cell. 139. PMID 19945384 DOI: 10.1016/J.Cell.2009.11.023 |
0.758 |
|
| 2009 |
Farese RV, Walther TC. Lipid Droplets Finally Get a Little R-E-S-P-E-C-T Cell. 139: 855-860. PMID 19945371 DOI: 10.1016/J.Cell.2009.11.005 |
0.717 |
|
| 2009 |
Guo Y, Cordes KR, Farese RV, Walther TC. Lipid droplets at a glance Journal of Cell Science. 122: 749-752. PMID 19261844 DOI: 10.1242/Jcs.037630 |
0.747 |
|
| 2009 |
Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. The Journal of Biological Chemistry. 284: 5352-61. PMID 19049983 DOI: 10.1074/Jbc.M805768200 |
0.736 |
|
| 2009 |
Walther TC, Farese RV. The life of lipid droplets Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1791: 459-466. PMID 19041421 DOI: 10.1016/J.Bbalip.2008.10.009 |
0.738 |
|
| 2008 |
Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 453: 657-61. PMID 18408709 DOI: 10.1038/Nature06928 |
0.774 |
|
| 2006 |
Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta. Cell Metabolism. 3: 343-53. PMID 16679292 DOI: 10.1016/J.Cmet.2006.04.005 |
0.338 |
|
| 2006 |
Yen CLE, Farese RV. Fat breakdown: A function for CGI-58 (ABHD5) provides a new piece of the puzzle Cell Metabolism. 3: 305-307. PMID 16679288 DOI: 10.1016/j.cmet.2006.04.001 |
0.326 |
|
| 2003 |
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 100: 3077-82. PMID 12629214 DOI: 10.1073/Pnas.0630588100 |
0.301 |
|
| 1998 |
Farese RV, Herz J. Cholesterol metabolism and embryogenesis Trends in Genetics. 14: 115-120. PMID 9540409 DOI: 10.1016/S0168-9525(97)01377-2 |
0.323 |
|
| 1980 |
Farese RV, Prudente WJ, Chuang LT. Non-esterified cholesterol-rich adrenal lipid fractions: Preparation, properties and preferential utilization for cholesterol side-chain cleavage by corticotropin-stimulated adrenal mitochondria Biochemical Journal. 186: 145-152. PMID 6245638 |
0.319 |
|
| 1978 |
Farese RV, Prudente WJ. Corticotropin-induced changes in a soluble desmolase preparation Bba - General Subjects. 539: 142-161. PMID 24476 DOI: 10.1016/0304-4165(78)90002-8 |
0.303 |
|
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