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David C. Zappulla, Ph.D. - Publications

Affiliations: 
2008-2017 Department of Biology Johns Hopkins University, Baltimore, MD 
 2017-2018 Department of Molecular Biology & Genetics Johns Hopkins University, Baltimore, MD 
 2018- Department of Biological Sciences Lehigh University, Bethlehem, PA, United States 
Area:
telomerase, telomeres, silencing, dna replication, yeast, RNA, RNP, ncRNA
Website:
https://www.lehigh.edu/~inbios/Faculty/Zappulla.html
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lebo KJ, Zappulla DC. Inverse-Folding Design of Yeast Telomerase RNA Increases Activity In Vitro. Non-Coding Rna. 9. PMID 37736897 DOI: 10.3390/ncrna9050051  0.849
2023 Lebo KJ, Zappulla DC. Inverse-folding design of yeast telomerase RNA increases activity . Biorxiv : the Preprint Server For Biology. PMID 36798419 DOI: 10.1101/2023.02.08.527468  0.848
2020 Mefford MA, Hass EP, Zappulla DC. A 4-base pair core-enclosing helix in telomerase RNA is essential for activity and for binding to the TERT catalytic protein subunit. Molecular and Cellular Biology. PMID 33046533 DOI: 10.1128/MCB.00239-20  0.831
2020 Zappulla DC. Yeast Telomerase RNA Flexibly Scaffolds Protein Subunits: Results and Repercussions. Molecules (Basel, Switzerland). 25. PMID 32545864 DOI: 10.3390/Molecules25122750  0.728
2020 Hass EP, Zappulla DC. Repositioning the Sm-Binding Site in Telomerase RNA Reveals RNP Organizational Flexibility and Sm-Directed 3'-End Formation. Non-Coding Rna. 6. PMID 32121425 DOI: 10.3390/Ncrna6010009  0.86
2017 Chen H, Xue J, Churikov D, Hass EP, Shi S, Lemon LD, Luciano P, Bertuch AA, Zappulla DC, Géli V, Wu J, Lei M. Structural Insights into Yeast Telomerase Recruitment to Telomeres. Cell. PMID 29290466 DOI: 10.1016/J.Cell.2017.12.008  0.845
2017 Niederer RO, Hass EP, Zappulla DC. Long Noncoding RNAs in the Yeast S. cerevisiae. Advances in Experimental Medicine and Biology. 1008: 119-132. PMID 28815538 DOI: 10.1007/978-981-10-5203-3_4  0.822
2016 Niederer RO, Papadopoulos N, Zappulla DC. Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq. Scientific Reports. 6: 19376. PMID 26786024 DOI: 10.1038/Srep19376  0.844
2015 Mefford MA, Zappulla DC. Physical connectivity mapping by circular permutation of human telomerase RNA reveals new regions critical for activity and processivity. Molecular and Cellular Biology. PMID 26503788 DOI: 10.1128/Mcb.00794-15  0.856
2015 Hass EP, Zappulla DC. The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae. Elife. 4. PMID 26218225 DOI: 10.7554/Elife.07750  0.803
2015 Niederer RO, Zappulla DC. Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE. Rna (New York, N.Y.). 21: 1053. PMID 25883220  0.846
2015 Lebo KJ, Niederer RO, Zappulla DC. A second essential function of the Est1-binding arm of yeast telomerase RNA. Rna (New York, N.Y.). 21: 862-76. PMID 25737580 DOI: 10.1261/Rna.049379.114  0.812
2015 Niederer RO, Zappulla DC. Refined secondary-structure models of the core of yeast and human telomerase RNAs directed by SHAPE. Rna (New York, N.Y.). 21: 254-61. PMID 25512567 DOI: 10.1261/Rna.048959.114  0.867
2015 Hass EP, Zappulla DC. Author response: The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae Elife. DOI: 10.7554/Elife.07750.017  0.797
2013 Mefford MA, Rafiq Q, Zappulla DC. RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP. The Embo Journal. 32: 2980-93. PMID 24129512 DOI: 10.1038/Emboj.2013.227  0.85
2012 Lebo KJ, Zappulla DC. Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo. Rna (New York, N.Y.). 18: 1666-78. PMID 22850424 DOI: 10.1261/Rna.033555.112  0.854
2011 Zappulla DC, Goodrich KJ, Arthur JR, Gurski LA, Denham EM, Stellwagen AE, Cech TR. Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP. Rna (New York, N.Y.). 17: 298-311. PMID 21177376 DOI: 10.1261/Rna.2483611  0.773
2009 Zappulla DC, Roberts JN, Goodrich KJ, Cech TR, Wuttke DS. Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p. Nucleic Acids Research. 37: 354-67. PMID 19043074 DOI: 10.1093/Nar/Gkn830  0.674
2008 Box JA, Bunch JT, Zappulla DC, Glynn EF, Baumann P. A flexible template boundary element in the RNA subunit of fission yeast telomerase. The Journal of Biological Chemistry. 283: 24224-33. PMID 18574244 DOI: 10.1074/Jbc.M802043200  0.767
2006 Zappulla DC, Cech TR. RNA as a flexible scaffold for proteins: yeast telomerase and beyond. Cold Spring Harbor Symposia On Quantitative Biology. 71: 217-24. PMID 17381300 DOI: 10.1101/Sqb.2006.71.011  0.795
2006 Zappulla DC, Maharaj AS, Connelly JJ, Jockusch RA, Sternglanz R. Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs. Bmc Molecular Biology. 7: 40. PMID 17094803 DOI: 10.1186/1471-2199-7-40  0.49
2006 Zappulla DC, Goodrich K, Cech TR. Erratum: Corrigendum: A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro Nature Structural & Molecular Biology. 13: 465-465. DOI: 10.1038/Nsmb0506-465A  0.781
2005 Zappulla DC, Goodrich K, Cech TR. A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro. Nature Structural & Molecular Biology. 12: 1072-7. PMID 16299517 DOI: 10.1038/Nsmb1019  0.816
2004 Zappulla DC, Cech TR. Yeast telomerase RNA: a flexible scaffold for protein subunits. Proceedings of the National Academy of Sciences of the United States of America. 101: 10024-9. PMID 15226497 DOI: 10.1073/Pnas.0403641101  0.823
2004 Andrulis ED, Zappulla DC, Alexieva-Botcheva K, Evangelista C, Sternglanz R. One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors. Genetics. 166: 631-5. PMID 15020450 DOI: 10.1534/Genetics.166.1.631  0.514
2002 Andrulis ED, Zappulla DC, Ansari A, Perrod S, Laiosa CV, Gartenberg MR, Sternglanz R. Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning. Molecular and Cellular Biology. 22: 8292-301. PMID 12417731 DOI: 10.1128/Mcb.22.23.8292-8301.2002  0.511
2002 Zappulla DC, Sternglanz R, Leatherwood J. Control of replication timing by a transcriptional silencer. Current Biology : Cb. 12: 869-75. PMID 12062049 DOI: 10.1016/S0960-9822(02)00871-0  0.504
2001 Xie W, Gai X, Zhu Y, Zappulla DC, Sternglanz R, Voytas DF. Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p. Molecular and Cellular Biology. 21: 6606-14. PMID 11533248 DOI: 10.1128/Mcb.21.19.6606-6614.2001  0.428
1998 Andrulis ED, Neiman AM, Zappulla DC, Sternglanz R. Perinuclear localization of chromatin facilitates transcriptional silencing. Nature. 394: 592-5. PMID 9707122 DOI: 10.1038/29100  0.542
1998 Tufarelli C, Fujiwara Y, Zappulla DC, Neufeld EJ. Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene. Developmental Biology. 200: 69-81. PMID 9698457 DOI: 10.1006/Dbio.1998.8950  0.472
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