Li Shen - Publications

Affiliations: 
Indiana University School of Medicine, Indianapolis, IN, United States 
Area:
Neuroimaging and genetics

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, ... ... Shen L, et al. Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering. Nature Communications. 15: 354. PMID 38191573 DOI: 10.1038/s41467-023-44271-2  0.395
2023 Wen J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, Yang Z, Erus G, Robert-Fitzgerald T, Singh A, Sotiras A, Boquet-Pujadas A, Mamourian E, Doshi J, Cui Y, Srinivasan D, Skampardoni I, ... ... Shen L, et al. Genomic loci influence patterns of structural covariance in the human brain. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300842120. PMID 38127979 DOI: 10.1073/pnas.2300842120  0.348
2023 Rosewood TJ, Nho K, Risacher SL, Gao S, Shen L, Foroud T, Saykin AJ. Genome-Wide Association Analysis across Endophenotypes in Alzheimer's Disease: Main Effects and Disease Stage-Specific Interactions. Genes. 14. PMID 38002954 DOI: 10.3390/genes14112010  0.363
2023 Lee BN, Wang J, Hall MA, Kim D, Stites SD, Shen L. Sex modifies effects of imaging and CSF biomarkers on cognitive and functional outcomes: a study of Alzheimer's disease. Neurobiology of Aging. 133: 67-77. PMID 37913627 DOI: 10.1016/j.neurobiolaging.2023.10.002  0.312
2023 Zhou Z, Tong B, Tarzanagh DA, Hou B, Saykin AJ, Long Q, Shen L. Multi-Group Tensor Canonical Correlation Analysis. Acm-Bcb ... ... : the ... Acm Conference On Bioinformatics, Computational Biology and Biomedicine. Acm Conference On Bioinformatics, Computational Biology and Biomedicine. 2023. PMID 37876849 DOI: 10.1145/3584371.3612962  0.364
2023 Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah I, Satterthwaite T, Shou H, Shen L, Toga AW, et al. Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability. Medrxiv : the Preprint Server For Health Sciences. PMID 37662256 DOI: 10.1101/2023.08.16.23294179  0.334
2023 Bao J, Wen J, Wen Z, Yang S, Cui Y, Yang Z, Erus G, Saykin AJ, Long Q, Davatzikos C, Shen L. Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer's disease. Neuroimage. 120346. PMID 37634885 DOI: 10.1016/j.neuroimage.2023.120346  0.443
2023 Sha J, Bao J, Liu K, Yang S, Wen Z, Wen J, Cui Y, Tong B, Moore JH, Saykin AJ, Davatzikos C, Long Q, Shen L. Preference Matrix Guided Sparse Canonical Correlation Analysis for Mining Brain Imaging Genetic Associations in Alzheimer's Disease. Methods (San Diego, Calif.). PMID 37507059 DOI: 10.1016/j.ymeth.2023.07.007  0.391
2023 Wang X, Feng Y, Tong B, Bao J, Ritchie MD, Saykin AJ, Moore JH, Urbanowicz R, Shen L. Exploring Automated Machine Learning for Cognitive Outcome Prediction from Multimodal Brain Imaging using STREAMLINE. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2023: 544-553. PMID 37350896  0.396
2023 Lee BN, Wang J, Nho K, Saykin AJ, Shen L. Discovering Precision AD Biomarkers with Varying Prognosis Effects in Genetics Driven Subpopulations. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2023: 340-349. PMID 37350892  0.336
2023 Tong B, Risacher SL, Bao J, Feng Y, Wang X, Ritchie MD, Moore JH, Urbanowicz R, Saykin AJ, Shen L. Comparing Amyloid Imaging Normalization Strategies for Alzheimer's Disease Classification using an Automated Machine Learning Pipeline. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2023: 525-533. PMID 37350880  0.341
2023 Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, ... Shen L, et al. The Genetic Heterogeneity of Multimodal Human Brain Age. Biorxiv : the Preprint Server For Biology. PMID 37333190 DOI: 10.1101/2023.04.13.536818  0.385
2023 Pala D, Lee B, Ning X, Kim D, Shen L. Mediation Analysis and Mixed-Effects Models for the Identification of Stage-specific Imaging Genetics Patterns in Alzheimer's Disease. Proceedings. Ieee International Conference On Bioinformatics and Biomedicine. 2022: 2667-2673. PMID 36824222 DOI: 10.1109/bibm55620.2022.9995405  0.362
2023 Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, ... ... Shen L, et al. Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering. Arxiv. PMID 36748000  0.315
2022 Zhou H, Zhang Y, Chen BY, Shen L, He L. Sparse Interpretation of Graph Convolutional Networks for Multi-Modal Diagnosis of Alzheimer's Disease. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 13438: 469-478. PMID 36827208 DOI: 10.1007/978-3-031-16452-1_45  0.32
2022 Reyes DM, Kim M, Chao H, Hahn J, Shen L, Yan P. Genomics transformer for diagnosing Parkinson's disease. ... Ieee-Embs International Conference On Biomedical and Health Informatics. Ieee-Embs International Conference On Biomedical and Health Informatics. 2022. PMID 36824448 DOI: 10.1109/bhi56158.2022.9926815  0.643
2022 Feng Y, Kim M, Yao X, Liu K, Long Q, Shen L. Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment. Bmc Bioinformatics. 23: 402. PMID 36175853 DOI: 10.1186/s12859-022-04946-x  0.696
2022 Wu R, Bao J, Kim M, Saykin AJ, Moore JH, Shen L. Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns. Genes. 13. PMID 36140686 DOI: 10.3390/genes13091520  0.708
2022 Kim M, Wu R, Yao X, Saykin AJ, Moore JH, Shen L. Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease. Bmc Medical Genomics. 15: 168. PMID 35915443 DOI: 10.1186/s12920-022-01323-8  0.731
2022 Baik JY, Kim M, Bao J, Long Q, Shen L. Identifying Alzheimer's genes via brain transcriptome mapping. Bmc Medical Genomics. 15: 116. PMID 35590321 DOI: 10.1186/s12920-022-01260-6  0.714
2022 Kim M, Kim J, Qu J, Huang H, Long Q, Sohn KA, Kim D, Shen L. Interpretable temporal graph neural network for prognostic prediction of Alzheimer's disease using longitudinal neuroimaging data. Proceedings. Ieee International Conference On Bioinformatics and Biomedicine. 2021: 1381-1384. PMID 35299717 DOI: 10.1109/bibm52615.2021.9669504  0.686
2022 Cong S, Yao X, Xie L, Yan J, Shen L. Genetic Influence Underlying Brain Connectivity Phenotype: A Study on Two Age-Specific Cohorts. Frontiers in Genetics. 12: 782953. PMID 35237294 DOI: 10.3389/fgene.2021.782953  0.329
2022 Lee B, Yao X, Shen L. Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1. Bmc Genomics. 23: 85. PMID 35086473 DOI: 10.1186/s12864-021-08269-8  0.301
2022 Bao J, Wen Z, Kim M, Zhao X, Lee BN, Jung SH, Davatzikos C, Saykin AJ, Thompson PM, Kim D, Zhao Y, Shen L. Identifying highly heritable brain amyloid phenotypes through mining Alzheimer's imaging and sequencing biobank data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 27: 109-120. PMID 34890141  0.727
2022 Bao J, Wen Z, Kim M, Saykin AJ, Thompson PM, Zhao Y, Shen L. Identifying imaging genetic associations via regional morphometricity estimation. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 27: 97-108. PMID 34890140  0.712
2021 Zhao Y, Zhao X, Kim M, Bao J, Shen L. A Novel Bayesian Semi-parametric Model for Learning Heritable Imaging Traits. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 12905: 678-687. PMID 35299630 DOI: 10.1007/978-3-030-87240-3_65  0.728
2021 Kim M, Min EJ, Liu K, Yan J, Saykin AJ, Moore JH, Long Q, Shen L. Multi-task learning based structured sparse canonical correlation analysis for brain imaging genetics. Medical Image Analysis. 76: 102297. PMID 34871929 DOI: 10.1016/j.media.2021.102297  0.74
2021 Kim M, Bao J, Liu K, Park BY, Park H, Baik JY, Shen L. A structural enriched functional network: An application to predict brain cognitive performance. Medical Image Analysis. 71: 102026. PMID 33848962 DOI: 10.1016/j.media.2021.102026  0.671
2020 Kim M, Bao J, Liu K, Park BY, Park H, Shen L. Structural Connectivity Enriched Functional Brain Network using Simplex Regression with GraphNet. Machine Learning in Medical Imaging. Mlmi (Workshop). 12436: 292-302. PMID 34766171 DOI: 10.1007/978-3-030-59861-7_30  0.688
2020 Kim M, Won JH, Hong J, Kwon J, Park H, Shen L. DEEP NETWORK-BASED FEATURE SELECTION FOR IMAGING GENETICS: APPLICATION TO IDENTIFYING BIOMARKERS FOR PARKINSON'S DISEASE. Proceedings. Ieee International Symposium On Biomedical Imaging. 2020. PMID 34594479 DOI: 10.1109/isbi45749.2020.9098471  0.743
2020 Yingxuan E, Yao X, Liu K, Risacher SL, Saykin AJ, Long Q, Zhao Y, Shen L. Polygenic mediation analysis of Alzheimer's disease implicated intermediate amyloid imaging phenotypes. Amia ... Annual Symposium Proceedings. Amia Symposium. 2020: 422-431. PMID 33936415  0.338
2020 Feng Y, Liu K, Kim M, Long Q, Yao X, Shen L. Deep Multiview Learning to Identify Population Structure with Multimodal Imaging. Proceedings. Ieee International Symposium On Bioinformatics and Bioengineering. 2020: 308-314. PMID 33654579 DOI: 10.1109/bibe50027.2020.00057  0.689
2020 Meng X, Li J, Zhang Q, Chen F, Bian C, Yao X, Yan J, Xu Z, Risacher SL, Saykin AJ, Liang H, Shen L. Multivariate genome wide association and network analysis of subcortical imaging phenotypes in Alzheimer's disease. Bmc Genomics. 21: 896. PMID 33372590 DOI: 10.1186/s12864-020-07282-7  0.333
2020 Cong S, Yao X, Huang Z, Risacher SL, Nho K, Saykin AJ, Shen L. Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data. Neurobiology of Aging. 95: 81-93. PMID 32768867 DOI: 10.1016/J.Neurobiolaging.2020.07.005  0.397
2020 Du L, Liu F, Liu K, Yao X, Risacher SL, Han J, Saykin AJ, Shen L. Associating Multi-modal Brain Imaging Phenotypes and Genetic Risk Factors via A Dirty Multi-task Learning Method. Ieee Transactions On Medical Imaging. PMID 32746095 DOI: 10.1109/Tmi.2020.2995510  0.415
2020 Du L, Liu F, Liu K, Yao X, Risacher SL, Han J, Guo L, Saykin AJ, Shen L. Identifying diagnosis-specific genotype-phenotype associations via joint multitask sparse canonical correlation analysis and classification. Bioinformatics (Oxford, England). 36: i371-i379. PMID 32657360 DOI: 10.1093/Bioinformatics/Btaa434  0.393
2020 Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, ... ... Shen L, et al. The genetic architecture of the human cerebral cortex. Science (New York, N.Y.). 367. PMID 32193296 DOI: 10.1126/Science.Aay6690  0.368
2020 Yan J, Raja V V, Huang Z, Amico E, Nho K, Fang S, Sporns O, Wu YC, Saykin A, Goni J, Shen L. Brain-wide structural connectivity alterations under the control of Alzheimer risk genes. International Journal of Computational Biology and Drug Design. 13: 58-70. PMID 32095160 DOI: 10.1504/Ijcbdd.2020.10026789  0.399
2020 Du L, Liu K, Yao X, Risacher SL, Han J, Saykin AJ, Guo L, Shen L. Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured SCCA approach. Medical Image Analysis. 61: 101656. PMID 32062154 DOI: 10.1016/J.Media.2020.101656  0.415
2019 Yao X, Cong S, Yan J, Risacher SL, Saykin AJ, Moore JH, Shen L. Regional Imaging Genetic Enrichment Analysis. Bioinformatics (Oxford, England). PMID 31860065 DOI: 10.1093/Bioinformatics/Btz948  0.392
2019 Du L, Liu K, Yao X, Risacher SL, Guo L, Saykin AJ, Shen L. DIAGNOSIS STATUS GUIDED BRAIN IMAGING GENETICS VIA INTEGRATED REGRESSION AND SPARSE CANONICAL CORRELATION ANALYSIS. Proceedings. Ieee International Symposium On Biomedical Imaging. 2019: 356-359. PMID 31844486 DOI: 10.1109/ISBI.2019.8759489  0.302
2019 Hao X, Bao Y, Guo Y, Yu M, Zhang D, Risacher SL, Saykin AJ, Yao X, Shen L. Multi-modal neuroimaging feature selection with consistent metric constraint for diagnosis of Alzheimer's disease. Medical Image Analysis. 60: 101625. PMID 31841947 DOI: 10.1016/J.Media.2019.101625  0.375
2019 Brand L, Nichols K, Wang H, Shen L, Huang H. Joint Multi-Modal Longitudinal Regression and Classification for Alzheimer's Disease Prediction. Ieee Transactions On Medical Imaging. PMID 31841400 DOI: 10.1109/Tmi.2019.2958943  0.382
2019 Liu M, Li F, Yan H, Wang K, Ma Y, Shen L, Xu M. A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease. Neuroimage. 116459. PMID 31837471 DOI: 10.1016/J.Neuroimage.2019.116459  0.388
2019 Li J, Chen F, Zhang Q, Meng X, Yao X, Risacher SL, Yan J, Saykin AJ, Liang H, Shen L. Genome-wide Network-assisted Association and Enrichment Study of Amyloid Imaging Phenotype in Alzheimer's Disease. Current Alzheimer Research. PMID 31755389 DOI: 10.2174/1567205016666191121142558  0.4
2019 Yao X, Cong S, Yan J, Risacher SL, Saykin AJ, Moore JH, Shen L. Mining Regional Imaging Genetic Associations via Voxel-wise Enrichment Analysis. ... Ieee-Embs International Conference On Biomedical and Health Informatics. Ieee-Embs International Conference On Biomedical and Health Informatics. 2019. PMID 31742256 DOI: 10.1109/BHI.2019.8834450  0.336
2019 Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, ... ... Shen L, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. PMID 31636452 DOI: 10.1038/S41588-019-0511-Y  0.381
2019 Du L, Liu K, Yao X, Risacher S, Han J, Saykin A, Guo L, Shen L. Multi-Task Sparse Canonical Correlation Analysis with Application to Multi-Modal Brain Imaging Genetics. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 31634139 DOI: 10.1109/Tcbb.2019.2947428  0.407
2019 Wang M, Shao W, Hao X, Shen L, Zhang D. Identify Consistent Cross-Modality Imaging Genetic Patterns via Discriminant Sparse Canonical Correlation Analysis. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 31581090 DOI: 10.1109/Tcbb.2019.2944825  0.392
2019 Du L, Liu K, Zhu L, Yao X, Risacher SL, Guo L, Saykin AJ, Shen L. Identifying progressive imaging genetic patterns via multi-task sparse canonical correlation analysis: a longitudinal study of the ADNI cohort. Bioinformatics (Oxford, England). 35: i474-i483. PMID 31510645 DOI: 10.1093/Bioinformatics/Btz320  0.41
2019 Yan J, Deng C, Luo L, Wang X, Yao X, Shen L, Huang H. Identifying Imaging Markers for Predicting Cognitive Assessments Using Wasserstein Distances Based Matrix Regression. Frontiers in Neuroscience. 13: 668. PMID 31354405 DOI: 10.3389/Fnins.2019.00668  0.359
2019 Yao X, Risacher SL, Nho K, Saykin AJ, Wang Z, Shen L. Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene. Neurobiology of Aging. 81: 213-221. PMID 31319229 DOI: 10.1016/J.Neurobiolaging.2019.06.003  0.416
2019 Wang M, Hao X, Huang J, Wang K, Shen L, Xu X, Zhang D, Liu M. Hierarchical Structured Sparse Learning for Schizophrenia Identification. Neuroinformatics. PMID 31016571 DOI: 10.1007/S12021-019-09423-0  0.313
2018 Wang X, Chen H, Yan J, Nho K, Risacher SL, Saykin AJ, Shen L, Huang H. Quantitative trait loci identification for brain endophenotypes via new additive model with random networks. Bioinformatics (Oxford, England). 34: i866-i874. PMID 30423101 DOI: 10.1093/Bioinformatics/Bty557  0.439
2018 Wang X, Yan J, Yao X, Kim S, Nho K, Risacher SL, Saykin AJ, Shen L, Huang H. Longitudinal Genotype-Phenotype Association Study through Temporal Structure Auto-Learning Predictive Model. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 25: 809-824. PMID 30011249 DOI: 10.1089/Cmb.2018.0008  0.408
2018 Hao X, Yao X, Risacher S, Saykin A, Yu J, Wang H, Tan L, Shen L, Zhang D. Identifying Candidate Genetic Associations with MRI-derived AD-related ROI via Tree-guided Sparse Learning. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 29993890 DOI: 10.1109/Tcbb.2018.2833487  0.408
2018 Zigon B, Li H, Yao X, Fang S, Hasan MA, Yan J, Moore JH, Saykin AJ, Shen L. GPU Accelerated Browser for Neuroimaging Genomics. Neuroinformatics. PMID 29691798 DOI: 10.1007/S12021-018-9376-Y  0.329
2018 Cong S, Risacher SL, West JD, Wu YC, Apostolova LG, Tallman E, Rizkalla M, Salama P, Saykin AJ, Shen L. Volumetric comparison of hippocampal subfields extracted from 4-minute accelerated vs. 8-minute high-resolution T2-weighted 3T MRI scans. Brain Imaging and Behavior. PMID 29305751 DOI: 10.1007/S11682-017-9819-3  0.347
2017 Liu K, Yao X, Yan J, Chasioti D, Risacher S, Nho K, Saykin A, Shen L. Transcriptome-Guided Imaging Genetic Analysis via a Novel Sparse CCA Algorithm. Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics : First International Workshop, Grail 2017, 6th International Workshop, Mfca 2017, and Third International Workshop, Micgen 2017, Held in Conjunction With M.... 10551: 220-229. PMID 30294724 DOI: 10.1007/978-3-319-67675-3_20  0.334
2017 Wang X, Yan J, Yao X, Kim S, Nho K, Risacher SL, Saykin AJ, Shen L, Huang H. Longitudinal Genotype-Phenotype Association Study via Temporal Structure Auto-Learning Predictive Model. Research in Computational Molecular Biology : ... Annual International Conference, Recomb ... : Proceedings. Recomb (Conference : 2005-). 10229: 287-302. PMID 29696245 DOI: 10.1007/978-3-319-56970-3_18  0.348
2017 Yao X, Yan J, Ginda M, Börner K, Saykin AJ, Shen L. Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer's disease neuroimaging initiative. Plos One. 12: e0186095. PMID 29095836 DOI: 10.1371/Journal.Pone.0186095  0.347
2017 Du L, Liu K, Yao X, Yan J, Risacher SL, Han J, Guo L, Saykin AJ, Shen L. Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty. Scientific Reports. 7: 14052. PMID 29070790 DOI: 10.1038/S41598-017-13930-Y  0.421
2017 Du L, Liu K, Zhang T, Yao X, Yan J, Risacher SL, Han J, Guo L, Saykin AJ, Shen L. A Novel SCCA Approach via Truncated ℓ1-norm and Truncated Group Lasso for Brain Imaging Genetics. Bioinformatics (Oxford, England). PMID 28968815 DOI: 10.1093/Bioinformatics/Btx594  0.415
2017 Hao X, Li C, Yan J, Yao X, Risacher SL, Saykin AJ, Shen L, Zhang D. Identification of associations between genotypes and longitudinal phenotypes via temporally-constrained group sparse canonical correlation analysis. Bioinformatics (Oxford, England). 33: i341-i349. PMID 28881979 DOI: 10.1093/Bioinformatics/Btx245  0.407
2017 Du L, Zhang T, Liu K, Yan J, Yao X, Risacher SL, Saykin AJ, Han J, Guo L, Shen L. Identifying Associations Between Brain Imaging Phenotypes and Genetic Factors via A Novel Structured SCCA Approach. Information Processing in Medical Imaging : Proceedings of the ... Conference. 10265: 543-555. PMID 28867917 DOI: 10.1007/978-3-319-59050-9_43  0.339
2017 Li H, Fang S, Contreras JA, West JD, Risacher SL, Wang Y, Sporns O, Saykin AJ, Goñi J, Shen L. Brain explorer for connectomic analysis. Brain Informatics. PMID 28836134 DOI: 10.1007/S40708-017-0071-9  0.336
2017 Li J, Zhang Q, Chen F, Meng X, Liu W, Chen D, Yan J, Kim S, Wang L, Feng W, Saykin AJ, Liang H, Shen L. Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort. Neurobiology of Aging. PMID 28641921 DOI: 10.1016/J.Neurobiolaging.2017.05.007  0.367
2017 Nho K, Kim S, Horgusluoglu E, Risacher SL, Shen L, Kim D, Lee S, Foroud T, Shaw LM, Trojanowski JQ, Aisen PS, Petersen RC, Jack CR, Weiner MW, Green RC, et al. Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer's disease. Bmc Medical Genomics. 10: 29. PMID 28589856 DOI: 10.1186/S12920-017-0267-0  0.366
2017 Yao X, Yan J, Liu K, Kim S, Nho K, Risacher SL, Greene CS, Moore JH, Saykin AJ, Shen L. Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules. Bioinformatics (Oxford, England). PMID 28575147 DOI: 10.1093/Bioinformatics/Btx344  0.309
2017 Cong W, Meng X, Li J, Zhang Q, Chen F, Liu W, Wang Y, Cheng S, Yao X, Yan J, Kim S, Saykin AJ, Liang H, Shen L. Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort. Bmc Genomics. 18: 421. PMID 28558704 DOI: 10.1186/S12864-017-3798-Z  0.382
2017 Toledo JB, Arnold M, Kastenmüller G, Chang R, Baillie RA, Han X, Thambisetty M, Tenenbaum JD, Suhre K, Thompson JW, John-Williams LS, MahmoudianDehkordi S, Rotroff DM, Jack JR, Motsinger-Reif A, ... ... Shen L, et al. Metabolic network failures in Alzheimer's disease-A biochemical road map. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28341160 DOI: 10.1016/J.Jalz.2017.01.020  0.371
2017 Hao X, Li C, Du L, Yao X, Yan J, Risacher SL, Saykin AJ, Shen L, Zhang D. Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease. Scientific Reports. 7: 44272. PMID 28291242 DOI: 10.1038/Srep44272  0.467
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Shen L, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624  0.39
2017 Raja V, Risacher SL, Nho K, Shen L, Saykin AJ, Yan J. [P2-120]: INVESTIGATION OF GENETIC INFLUENCES ON ATROPHY RATE DURING THE MCI DISEASE STAGE USING A BOOTSTRAP-ENHANCED SPARSE ASSOCIATION MODEL Alzheimer's & Dementia. 13: P653-P653. DOI: 10.1016/J.Jalz.2017.06.770  0.34
2017 Sasner M, Carter GW, Howell G, Rizzo SJ, Williams HM, Preuss C, Wang X, Philip V, Ananda G, Uyar A, Onos K, Logsdon B, Omberg L, Mangravite LM, Lamb BT, ... ... Shen L, et al. [P4-060]: MODEL ORGANISM DEVELOPMENT AND EVALUATION FOR LATE-ONSET ALZHEIMER's DISEASE: MODEL-AD Alzheimer's & Dementia. 13: P1280-P1281. DOI: 10.1016/J.Jalz.2017.06.1925  0.324
2016 Du L, Zhang T, Liu K, Yao X, Yan J, Risacher SL, Guo L, Saykin AJ, Shen L. Sparse Canonical Correlation Analysis via Truncated ℓ1-norm with Application to Brain Imaging Genetics. Proceedings. Ieee International Conference On Bioinformatics and Biomedicine. 2016: 707-711. PMID 28989812 DOI: 10.1109/BIBM.2016.7822605  0.323
2016 Yan J, Risacher SL, Nho K, Saykin AJ, Shen LI. IDENTIFICATION OF DISCRIMINATIVE IMAGING PROTEOMICS ASSOCIATIONS IN ALZHEIMER'S DISEASE VIA A NOVEL SPARSE CORRELATION MODEL. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 94-104. PMID 27896965  0.334
2016 Yao X, Yan J, Kim S, Nho K, Risacher SL, Inlow M, Moore JH, Saykin AJ, Shen L. Two-dimensional enrichment analysis for mining high-level imaging genetic associations. Brain Informatics. PMID 27747820 DOI: 10.1007/S40708-016-0052-4  0.453
2016 Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Shen L, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398  0.386
2016 Du L, Huang H, Yan J, Kim S, Risacher S, Inlow M, Moore J, Saykin A, Shen L. Structured sparse CCA for brain imaging genetics via graph OSCAR. Bmc Systems Biology. 10: 68. PMID 27585988 DOI: 10.1186/S12918-016-0312-1  0.367
2016 Frost HR, Shen L, Saykin AJ, Williams SM, Moore JH. Identifying significant gene-environment interactions using a combination of screening testing and hierarchical false discovery rate control. Genetic Epidemiology. PMID 27578615 DOI: 10.1002/Gepi.21997  0.334
2016 Hao X, Yao X, Yan J, Risacher SL, Saykin AJ, Zhang D, Shen L. Identifying Multimodal Intermediate Phenotypes Between Genetic Risk Factors and Disease Status in Alzheimer's Disease. Neuroinformatics. PMID 27277494 DOI: 10.1007/S12021-016-9307-8  0.466
2016 Du L, Huang H, Yan J, Kim S, Risacher SL, Inlow M, Moore JH, Saykin AJ, Shen L. Structured Sparse Canonical Correlation Analysis for Brain Imaging Genetics: An Improved GraphNet Method. Bioinformatics (Oxford, England). PMID 26801960 DOI: 10.1093/Bioinformatics/Btw033  0.348
2016 Song A, Yan J, Kim S, Risacher SL, Wong AK, Saykin AJ, Shen L, Greene CS. Network-based analysis of genetic variants associated with hippocampal volume in Alzheimer's disease: a study of ADNI cohorts. Biodata Mining. 9: 3. PMID 26788126 DOI: 10.1186/S13040-016-0082-8  0.403
2016 Hao X, Yan J, Yao X, Risacher SL, Saykin AJ, Zhang D, Shen LI. DIAGNOSIS-GUIDED METHOD FOR IDENTIFYING MULTI-MODALITY NEUROIMAGING BIOMARKERS ASSOCIATED WITH GENETIC RISK FACTORS IN ALZHEIMER'S DISEASE. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 108-19. PMID 26776178  0.343
2016 Yan J, Risacher SL, Nho K, Shen L, Saykin AJ. Identification Of Discriminative Brain Imaging And Genomic Associations: An Alzheimer’S Disease Study Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.359  0.386
2016 Kim S, Toledo JB, Nho K, Risacher SL, Shen L, Thompson JW, Williams LSJ, Tenenbaum J, Han X, Baillie RA, Thambisetty M, Casanova R, Varma S, Legido-Quigley C, Mahmoudiandehkordi S, et al. Genetic Influence On Levels Of Targeted Metabolites Associated With Alzheimer’S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.276  0.331
2016 Kim S, Nho K, Shen L, Franklin EE, Morris JC, Cairns NJ, Saykin AJ. Influence Of Parkinson’S Disease Candidate Genes On Lewy Body Pathology In Autopsy-Confirmed Alzheimer'S Disease Cases Alzheimers & Dementia. 12: 854. DOI: 10.1016/J.Jalz.2016.06.1748  0.319
2016 Nho K, Kim S, Horgousluoglu E, Risacher SL, Shen L, Thompson PM, Potkin SG, Gunn-Moore F, Saykin AJ. P2-098: Whole Brain Surface-Based Analysis Identified Brain Atrophy Associated with SNPS in FRMD6 Linked to Alzheimer's Disease Alzheimer's & Dementia. 12: P648-P650. DOI: 10.1016/J.Jalz.2016.06.1303  0.372
2015 Thompson PM, Andreassen OA, Arias-Vasquez A, Bearden CE, Boedhoe PS, Brouwer RM, Buckner RL, Buitelaar JK, Bulaeva KB, Cannon DM, Cohen RA, Conrod PJ, Dale AM, Deary IJ, Dennis EL, ... ... Shen L, et al. ENIGMA and the Individual: Predicting Factors that Affect the Brain in 35 Countries Worldwide. Neuroimage. PMID 26658930 DOI: 10.1016/J.Neuroimage.2015.11.057  0.393
2015 Du L, Yan J, Kim S, Risacher SL, Huang H, Inlow M, Moore JH, Saykin AJ, Shen L. GN-SCCA: GraphNet based Sparse Canonical Correlation Analysis for Brain Imaging Genetics. Brain Informatics and Health : 8th International Conference, Bih 2015, London, Uk, August 30-September 2, 2015. Proceedings / Yike Guo, Karl Friston, Faisal Aldo, Sean Hill, Hanchuan Peng (Eds.). Bih (Conference) (8th : 2015 : London, E.... 9250: 275-284. PMID 26636135  0.336
2015 Yao X, Yan J, Kim S, Nho K, Risacher SL, Inlow M, Moore JH, Saykin AJ, Shen L. Two-dimensional Enrichment Analysis for Mining High-level Imaging Genetic Associations. Brain Informatics and Health : 8th International Conference, Bih 2015, London, Uk, August 30-September 2, 2015. Proceedings / Yike Guo, Karl Friston, Faisal Aldo, Sean Hill, Hanchuan Peng (Eds.). Bih (Conference) (8th : 2015 : London, E.... 9250: 115-124. PMID 26568986 DOI: 10.1007/978-3-319-23344-4_12  0.382
2015 Li J, Zhang Q, Chen F, Yan J, Kim S, Wang L, Feng W, Saykin AJ, Liang H, Shen L. Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort. Biomed Research International. 2015: 647389. PMID 26421299 DOI: 10.1155/2015/647389  0.423
2015 Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, McDonald BC, Yoder KK, Hutchins GD, West JD, Tallman EF, Gao S, Foroud TM, Farlow MR, De Jager PL, Bennett DA, et al. GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP. Brain : a Journal of Neurology. PMID 26268530 DOI: 10.1093/Brain/Awv231  0.385
2015 Saykin AJ, Shen L, Yao X, Kim S, Nho K, Risacher SL, Ramanan VK, Foroud TM, Faber KM, Sarwar N, Munsie LM, Hu X, Soares HD, Potkin SG, Thompson PM, et al. Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 792-814. PMID 26194313 DOI: 10.1016/J.Jalz.2015.05.009  0.379
2015 Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Cedarbaum J, Green RC, Harvey D, Jack CR, Jagust W, Luthman J, Morris JC, Petersen RC, Saykin AJ, Shaw L, ... Shen L, et al. 2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: e1-e120. PMID 26073027 DOI: 10.1016/J.Jalz.2014.11.001  0.391
2015 Risacher SL, Kim S, Nho K, Foroud T, Shen L, Petersen RC, Jack CR, Beckett LA, Aisen PS, Koeppe RA, Jagust WJ, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ, et al. APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25960448 DOI: 10.1016/J.Jalz.2015.03.003  0.333
2015 Yan J, Kim S, Nho K, Chen R, Risacher SL, Moore JH, Saykin AJ, Shen L. Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease. Frontiers in Genetics. 6: 117. PMID 25859259 DOI: 10.3389/Fgene.2015.00117  0.37
2015 Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, ... ... Shen L, et al. Common genetic variants influence human subcortical brain structures. Nature. 520: 224-9. PMID 25607358 DOI: 10.1038/Nature14101  0.398
2015 Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, et al. Protective variant for hippocampal atrophy identified by whole exome sequencing. Annals of Neurology. 77: 547-52. PMID 25559091 DOI: 10.1002/Ana.24349  0.372
2015 Yan J, Li T, Wang H, Huang H, Wan J, Nho K, Kim S, Risacher SL, Saykin AJ, Shen L. Cortical surface biomarkers for predicting cognitive outcomes using group l2,1 norm. Neurobiology of Aging. 36: S185-93. PMID 25444599 DOI: 10.1016/J.Neurobiolaging.2014.07.045  0.314
2015 Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, Foroud TM, Aisen PS, Petersen RC, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ. Gwas of longitudinal amyloid PET identifies IL1RAP as a new potential Alzheimer's disease target Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.369  0.323
2015 Yao X, Yan J, Kim S, Nho K, Risacher SL, Börner K, Foroud TM, Thompson PM, Potkin SG, Sarwar N, Munsie L, Soares H, Green RC, Toga AW, Weiner MW, ... ... Shen L, et al. P1-201: Genetic findings using ADNI multimodal quantitative phenotypes: A 2014 update Alzheimer's & Dementia. 11: P426-P426. DOI: 10.1016/J.Jalz.2015.06.401  0.32
2015 Kim S, Nho K, Risacher SL, Shen L, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ. Mapre2 as a novel Alzheimer's disease target gene from gwas of CSF amyloid beta 1-42, tau and hyperphosphorylated tau in the ADNI cohort Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.1712  0.31
2014 Sheng J, Kim S, Yan J, Moore J, Saykin A, Shen L. DATA SYNTHESIS AND METHOD EVALUATION FOR BRAIN IMAGING GENETICS. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 2014: 1202-1205. PMID 25408823 DOI: 10.1109/ISBI.2014.6868091  0.31
2014 Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, et al. FASTKD2 is associated with memory and hippocampal structure in older adults. Molecular Psychiatry. PMID 25385369 DOI: 10.1038/Mp.2014.142  0.329
2014 Du L, Jingwen Y, Kim S, Risacher SL, Huang H, Inlow M, Moore JH, Saykin AJ, Shen L. A novel structure-aware sparse learning algorithm for brain imaging genetics. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 17: 329-36. PMID 25320816  0.352
2014 Zieselman AL, Fisher JM, Hu T, Andrews PC, Greene CS, Shen L, Saykin AJ, Moore JH. Computational genetics analysis of grey matter density in Alzheimer's disease. Biodata Mining. 7: 17. PMID 25165488 DOI: 10.1186/1756-0381-7-17  0.401
2014 Yan J, Du L, Kim S, Risacher SL, Huang H, Moore JH, Saykin AJ, Shen L. Transcriptome-guided amyloid imaging genetic analysis via a novel structured sparse learning algorithm. Bioinformatics (Oxford, England). 30: i564-71. PMID 25161248 DOI: 10.1093/Bioinformatics/Btu465  0.415
2014 Wan J, Zhang Z, Rao BD, Fang S, Yan J, Saykin AJ, Shen L. Identifying the neuroanatomical basis of cognitive impairment in Alzheimer's disease by correlation- and nonlinearity-aware sparse Bayesian learning. Ieee Transactions On Medical Imaging. 33: 1475-87. PMID 24710828 DOI: 10.1109/Tmi.2014.2314712  0.357
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, ... ... Shen L, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/S11682-013-9269-5  0.364
2014 Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, et al. Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging and Behavior. 8: 183-207. PMID 24092460 DOI: 10.1007/S11682-013-9262-Z  0.456
2014 Ramanan VK, Risacher SL, Nho K, Kim S, Swaminathan S, Shen L, Foroud TM, Hakonarson H, Huentelman MJ, Aisen PS, Petersen RC, Green RC, Jack CR, Koeppe RA, Jagust WJ, et al. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Molecular Psychiatry. 19: 351-7. PMID 23419831 DOI: 10.1038/Mp.2013.19  0.414
2014 Yan J, Kim S, Nho KT, Risacher SL, Moore J, Saykin AJ, Shen L. Effects Of Newly Identified Top Ad Candidate Genes On Memory Performance: Snp, Gene, And Epistasis Analyses In Adni Alzheimers & Dementia. 10: 388. DOI: 10.1016/J.Jalz.2014.05.180  0.309
2014 Ramanan VK, Nho K, Risacher SL, Kim S, Shen L, Swaminathan S, Foroud TM, Aisen P, Hakonarson H, Huentelman M, Jack C, Jagust W, Petersen RC, Potkin S, Shaw L, et al. P3-024: NEXT-GENERATION SEQUENCING OF THE BCHE LOCUS IDENTIFIES A FUNCTIONAL SNP ASSOCIATED WITH ALZHEIMER'S DISEASE BIOMARKERS AND AGE OF ONSET Alzheimer's & Dementia. 10: P636-P636. DOI: 10.1016/J.Jalz.2014.05.1111  0.411
2014 Nho KT, Kim S, Risacher SL, Shen L, Foroud T, Aisen P, Petersen R, Jack C, Weiner MW, Green R, Toga A, Saykin AJ. P3-019: RARE VARIANT IN PLD3 IS ASSOCIATED WITH ALZHEIMER'S PATTERN OF NEURODEGENERATIVE CHANGES Alzheimer's & Dementia. 10: P634-P634. DOI: 10.1016/J.Jalz.2014.05.1106  0.313
2014 Nho KT, Kim S, Risacher SL, Shen L, Foroud T, Aisen P, Petersen R, Jack C, Shaw L, Trojanowski JQ, Weiner MW, Green R, Toga A, Saykin AJ. P3-018: INFLUENCE OF RARE PSEN1 VARIANTS ON QUANTITATIVE STRUCTURAL IMAGING AND CSF PHENOTYPES IN LATE ONSET ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P633-P633. DOI: 10.1016/J.Jalz.2014.05.1105  0.392
2014 Nho KT, Kim S, Risacher SL, Shen L, Foroud T, Shaw L, Trojanowski JQ, Aisen P, Petersen R, Jack C, Weiner MW, Green R, Toga A, Saykin AJ. P3-017: ASSOCIATION ANALYSIS OF RARE VARIANTS NEAR THE APOE REGION WITH CEREBROSPINAL FLUID (CSF) BIOMARKERS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P632-P633. DOI: 10.1016/J.Jalz.2014.05.1104  0.34
2013 Yan J, Huang H, Risacher SL, Kim S, Inlow M, Moore JH, Saykin AJ, Shen L. Network-Guided Sparse Learning for Predicting Cognitive Outcomes from MRI Measures. Multimodal Brain Image Analysis : Third International Workshop, Mbia 2013, Held in Conjunction With Miccai 2013, Nagoya, Japan, September 22, 2013 : Proceedings / Li Shen, Tianming Liu, Pew-Thian Yap, Heng Huang, Dinggang Shen, Carl-Fre.... 8159: 202-210. PMID 25927078 DOI: 10.1007/978-3-319-02126-3_20  0.314
2013 De W, Nie F, Huang H, Yan J, Risacher SL, Saykin AJ, Shen L. Structural brain network constrained neuroimaging marker identification for predicting cognitive functions. Information Processing in Medical Imaging : Proceedings of the ... Conference. 23: 536-47. PMID 24683997 DOI: 10.1007/978-3-642-38868-2_45  0.328
2013 Kim S, Swaminathan S, Inlow M, Risacher SL, Nho K, Shen L, Foroud TM, Petersen RC, Aisen PS, Soares H, Toledo JB, Shaw LM, Trojanowski JQ, Weiner MW, McDonald BC, et al. Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel. Plos One. 8: e70269. PMID 23894628 DOI: 10.1371/Journal.Pone.0070269  0.35
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, et al. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Molecular Psychiatry. 18: 739. PMID 23787478 DOI: 10.1038/Mp.2013.81  0.309
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry. 18: 781-7. PMID 23608917 DOI: 10.1038/Mp.2013.24  0.394
2013 Risacher SL, Kim S, Shen L, Nho K, Foroud T, Green RC, Petersen RC, Jack CR, Aisen PS, Koeppe RA, Jagust WJ, Shaw LM, Trojanowski JQ, Weiner MW, Saykin AJ, et al. The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI). Frontiers in Aging Neuroscience. 5: 11. PMID 23554593 DOI: 10.3389/Fnagi.2013.00011  0.332
2013 Risacher S, Kim S, Klaunig J, Shen L, McDonald B, Farlow M, Ghetti B, Gao S, Wang Z, Zhou S, Saykin A. P1-051: DNA damage in peripheral blood cells is associated with Alzheimer's-related plasma proteins in individuals at risk for progression to Alzheimer's disease Alzheimer's & Dementia. 9: P171-P171. DOI: 10.1016/J.Jalz.2013.05.272  0.302
2013 Saykin A, Risacher S, McDonald B, West J, Tallman E, Flashman L, Wishart H, Rabin L, Pare N, O'Neill D, Kim S, Wang Y, Shen L, Santulli R, Farlow M. P4-193: Two-year outcome in older adults with cognitive complaints: Relation to baseline cognition, self- and informant ratings, genetics and imaging Alzheimer's & Dementia. 9: P775-P776. DOI: 10.1016/J.Jalz.2013.05.1584  0.305
2013 Shen L, Thompson P, Potkin S, Stone D, Kim S, Nho K, Ramanan V, Green R, Foroud T, Farrer L, Moore J, Bertram L, Weiner M, Saykin A. A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, fluid biomarkers, cognition and clinical status Alzheimers & Dementia. 9: 220. DOI: 10.1016/J.Jalz.2013.05.130  0.312
2013 Kaddurah-Daouk R, Doraiswamy PM, Zhu H, Kling M, Arnold S, Trojanowski J, Saykin A, Shen L, Kim S, Nho K, Matson W, Han X, Sharma S. Alterations in metabolic pathways and networks in mild cognitive impairment and early Alzheimer's disease Alzheimers & Dementia. 9: 571. DOI: 10.1016/J.Jalz.2013.05.1126  0.318
2013 Nho K, Kim S, Risacher S, Shen L, Sherva R, Green R, Weiner M, Saykin A. P3-013: Imaging genetics of the SPON1 gene variant rs11023139 in Alzheimer's disease Alzheimer's & Dementia. 9: P554-P555. DOI: 10.1016/J.Jalz.2013.05.1082  0.403
2013 Risacher S, Kim S, Klaunig J, Shen L, McDonald B, Farlow M, Ghetti B, Gao S, Wang Z, Zhou S, Saykin A. IC-P-109: DNA damage in peripheral blood cells is associated with Alzheimer's disease (AD)-related plasma proteins in individuals at risk for progression to AD Alzheimer's & Dementia. 9: P64-P64. DOI: 10.1016/J.Jalz.2013.05.106  0.312
2013 Wan J, Zhang Z, Fang S, Risacher S, Saykin A, Shen L. Sparse Bayesian learning for identifying the neuroanatomical basis of cognitive impairment in Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.103  0.34
2013 Kim S, Nho K, Shen L, Kling M, Han X, Zhu H, Sullivan P, Arnold S, Risacher S, Ramanan V, Doraiswamy PM, Trojanowski J, Kaddurah-Daouk R, Saykin A. Targeted lipidomic pathway-guided genetic association with Alzheimer's disease–relevant endophenotypes Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.339  0.347
2012 Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ. Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Plos One. 7: e50640. PMID 23227193 DOI: 10.1371/Journal.Pone.0050640  0.393
2012 Nho K, Risacher SL, Crane PK, DeCarli C, Glymour MM, Habeck C, Kim S, Lee GJ, Mormino E, Mukherjee S, Shen L, West JD, Saykin AJ. Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease. Brain Imaging and Behavior. 6: 551-67. PMID 23070747 DOI: 10.1007/S11682-012-9203-2  0.387
2012 Wang H, Nie F, Huang H, Yan J, Kim S, Nho K, Risacher SL, Saykin AJ, Shen L. From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs. Bioinformatics (Oxford, England). 28: i619-i625. PMID 22962490 DOI: 10.1093/Bioinformatics/Bts411  0.391
2012 Ramanan VK, Kim S, Holohan K, Shen L, Nho K, Risacher SL, Foroud TM, Mukherjee S, Crane PK, Aisen PS, Petersen RC, Weiner MW, Saykin AJ. Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks. Brain Imaging and Behavior. 6: 634-48. PMID 22865056 DOI: 10.1007/S11682-012-9196-X  0.36
2012 Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA. Multiple loci influencing hippocampal degeneration identified by genome scan. Annals of Neurology. 72: 65-75. PMID 22745009 DOI: 10.1002/Ana.23644  0.387
2012 Wang H, Nie F, Huang H, Risacher SL, Saykin AJ, Shen L. Identifying disease sensitive and quantitative trait-relevant biomarkers from multidimensional heterogeneous imaging genetics data via sparse multimodal multitask learning. Bioinformatics (Oxford, England). 28: i127-36. PMID 22689752 DOI: 10.1093/Bioinformatics/Bts228  0.451
2012 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, ... ... Shen L, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 44: 552-61. PMID 22504417 DOI: 10.1038/Ng.2250  0.398
2012 Swaminathan S, Shen L, Kim S, Inlow M, West JD, Faber KM, Foroud T, Mayeux R, Saykin AJ. Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study. Current Alzheimer Research. 9: 801-14. PMID 22486522 DOI: 10.2174/156720512802455331  0.378
2012 Ramanan VK, Shen L, Moore JH, Saykin AJ. Pathway analysis of genomic data: concepts, methods, and prospects for future development. Trends in Genetics : Tig. 28: 323-32. PMID 22480918 DOI: 10.1016/J.Tig.2012.03.004  0.312
2012 Meda SA, Narayanan B, Liu J, Perrone-Bizzozero NI, Stevens MC, Calhoun VD, Glahn DC, Shen L, Risacher SL, Saykin AJ, Pearlson GD. A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort. Neuroimage. 60: 1608-21. PMID 22245343 DOI: 10.1016/J.Neuroimage.2011.12.076  0.454
2012 Wang H, Nie F, Huang H, Kim S, Nho K, Risacher SL, Saykin AJ, Shen L. Identifying quantitative trait loci via group-sparse multitask regression and feature selection: an imaging genetics study of the ADNI cohort. Bioinformatics (Oxford, England). 28: 229-37. PMID 22155867 DOI: 10.1093/Bioinformatics/Btr649  0.423
2012 Swaminathan S, Shen L, Risacher SL, Yoder KK, West JD, Kim S, Nho K, Foroud T, Inlow M, Potkin SG, Huentelman MJ, Craig DW, Jagust WJ, Koeppe RA, Mathis CA, et al. Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. Brain Imaging and Behavior. 6: 1-15. PMID 21901424 DOI: 10.1007/S11682-011-9136-1  0.419
2012 Meda SA, Narayanan B, Liu J, Perrone-Bizzozero NI, Stevens MC, Calhoun VD, Glahn DC, Shen L, Risacher SL, Saykin AJ, Pearlson GD. Erratum to “A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's Disease in the ADNI cohort” [Neuroimage 60/3(2012) 1608–1621] Neuroimage. 62: 2177. DOI: 10.1016/J.Neuroimage.2012.03.058  0.395
2012 Nho K, Corneveaux J, Kim S, Lin H, Risacher S, Shen L, Liu Y, Foroud T, Inlow M, Siniard A, Reiman R, Green R, Jack C, Weiner M, Huentelman M, et al. Integrating whole-exome sequencing and imaging genetics to identify single-nucleotide variants associated with rate of hippocampal neurodegeneration in APOE-ε3/ε3 males with mild cognitive impairment Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.116  0.307
2012 Yan J, Li T, McDonald B, Risacher S, WuDunn D, Farlow M, Pepin SM, Flashman L, Wishart H, Santulli R, Saykin A, Shen L. P2-041: Visual contrast sensitivity as a novel biomarker: Discriminative analysis using elastic net to classify Alzheimer's disease, MCI and older adults with cognitive complaints Alzheimer's & Dementia. 8: P277-P278. DOI: 10.1016/J.Jalz.2012.05.744  0.318
2012 Saykin A, Shen L, Risacher S, Swaminathan S, Kim S, Ngo K, Thompson P, Potkin S, Farrer L. F2-02-03: Structural, functional and molecular imaging as intermediate phenotypes for studies of candidate genes, pathways and GWAS in Alzheimer's disease Alzheimer's & Dementia. 8: P232-P232. DOI: 10.1016/J.Jalz.2012.05.614  0.361
2012 Melville S, Buros J, Parrado T, Vardarajan B, Shen L, Risacher S, Kim S, Jun G, DeCarli C, Lunetta K, Baldwin C, Saykin A, Farrer L. Genome-wide association study of Alzheimer's-related brain MRI traits identifies several loci influencing degeneration of the hippocampus Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1984  0.392
2012 Ramanan V, Kim S, Holohan K, Shen L, Ngo K, Risacher S, Foroud T, Mukherjee S, Crane P, Aisen P, Petersen R, Weiner M, Saykin A. Common gene networks underlying memory impairment: A comparison of pathway analysis methods in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1844  0.347
2012 Li T, Yan J, Kim S, Swaminathan S, Risacher S, Shaw L, Trojanowski J, Aisen P, Petersen R, Weiner M, Saykin A, Shen L. O4-01-01: Classification of MCI and Alzheimer's disease from CSF biomarkers: An ADNI study of Aß, tau and P-tau versus 83 proteomic analytes Alzheimer's & Dementia. 8: P609-P610. DOI: 10.1016/J.Jalz.2012.05.1634  0.311
2012 Ramanan V, Shen L, Risacher S, Kim S, Boddu M, West J, Wang Y, Jing W, Crane P, Jack C, Weiner M, Saykin A. Hippocampal subfield atrophy in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Cohort: Relationships to diagnosis and memory impairment Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1434  0.318
2012 Risacher S, Kim S, Shen L, Ngo K, Foroud T, Petersen R, Aisen P, Jack C, Koeppe R, Jagust W, Weiner M, Saykin A. IC-P-098: The role of APOE-ɛ4 genotype in early mild cognitive impairment (EMCI): Preliminary results from ADNI-2 Alzheimer's & Dementia. 8: P56-P57. DOI: 10.1016/J.Jalz.2012.05.131  0.305
2012 West J, Wang Y, Magee T, McDonald B, Risacher S, Shen L, Ramanan V, Kim S, O'Neill D, Farlow M, Ghetti B, Saykin A. IC-P-060: Hippocampal subfield atrophy on 3T MRI in prodromal Alzheimer's disease and older adults with cognitive complaints Alzheimer's & Dementia. 8: P36-P36. DOI: 10.1016/J.Jalz.2012.05.093  0.3
2011 Swaminathan S, Kim S, Shen L, Risacher SL, Foroud T, Pankratz N, Potkin SG, Huentelman MJ, Craig DW, Weiner MW, Saykin AJ, The Alzheimer's Disease Neuroimaging Initiative Adni. Genomic Copy Number Analysis in Alzheimer's Disease and Mild Cognitive Impairment: An ADNI Study. International Journal of Alzheimer's Disease. 2011: 729478. PMID 21660214 DOI: 10.4061/2011/729478  0.38
2011 Hibar DP, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud T, Huentelman MJ, Potkin SG, Jack CR, Weiner MW, Toga AW, Thompson PM, et al. Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. Neuroimage. 56: 1875-91. PMID 21497199 DOI: 10.1016/J.Neuroimage.2011.03.077  0.409
2011 Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, Shaw LM, Trojanowski JQ, Potkin SG, Huentelman MJ, Craig DW, DeChairo BM, Aisen PS, Petersen RC, Weiner MW, et al. Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology. 76: 69-79. PMID 21123754 DOI: 10.1212/Wnl.0B013E318204A397  0.378
2011 Furney SJ, Simmons A, Breen G, Pedroso I, Lunnon K, Proitsi P, Hodges A, Powell J, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, ... ... Shen L, et al. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Molecular Psychiatry. 16: 1130-8. PMID 21116278 DOI: 10.1038/Mp.2010.123  0.402
2011 Kim S, Swaminathan S, Inlow M, Risacher S, Shen L, Foroud T, Shaw L, Trojanowski J, Soares H, Weiner M, Saykin A. Influence of genetic variation on plasma proteomics in AD, MCI and controls: Pairwise gene-protein analysis in the ADNI-1 cohort Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.084  0.337
2011 Risacher S, Shen L, West J, Flashman L, Wishart H, Rabin L, Pare N, Englert J, Schwartz E, Kim S, McDonald B, Curtain J, Pixley H, Santulli R, Saykin A. P1-342: Longitudinal structural MRI changes in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints: relationship to conversion status Alzheimer's & Dementia. 7: S221-S222. DOI: 10.1016/J.Jalz.2011.05.622  0.31
2010 Risacher SL, Shen L, West JD, Kim S, McDonald BC, Beckett LA, Harvey DJ, Jack CR, Weiner MW, Saykin AJ. Longitudinal MRI atrophy biomarkers: relationship to conversion in the ADNI cohort. Neurobiology of Aging. 31: 1401-18. PMID 20620664 DOI: 10.1016/J.Neurobiolaging.2010.04.029  0.368
2010 Sloan CD, Shen L, West JD, Wishart HA, Flashman LA, Rabin LA, Santulli RB, Guerin SJ, Rhodes CH, Tsongalis GJ, McAllister TW, Ahles TA, Lee SL, Moore JH, Saykin AJ. Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1060-9. PMID 20468060 DOI: 10.1002/Ajmg.B.31078  0.378
2010 Shen L, Saykin AJ, Kim S, Firpi HA, West JD, Risacher SL, McDonald BC, McHugh TL, Wishart HA, Flashman LA. Comparison of manual and automated determination of hippocampal volumes in MCI and early AD. Brain Imaging and Behavior. 4: 86-95. PMID 20454594 DOI: 10.1007/S11682-010-9088-X  0.365
2010 Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 265-73. PMID 20451875 DOI: 10.1016/J.Jalz.2010.03.013  0.435
2010 Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, et al. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proceedings of the National Academy of Sciences of the United States of America. 107: 8404-9. PMID 20404173 DOI: 10.1073/Pnas.0910878107  0.323
2010 Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ, Leow AD, Toga AW, Sul JH, Kang HM, Eskin E, Saykin AJ, Shen L, Foroud T, Pankratz N, et al. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage. 51: 542-54. PMID 20197096 DOI: 10.1016/J.Neuroimage.2010.02.068  0.408
2010 Stein JL, Hua X, Lee S, Ho AJ, Leow AD, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, et al. Voxelwise genome-wide association study (vGWAS). Neuroimage. 53: 1160-74. PMID 20171287 DOI: 10.1016/J.Neuroimage.2010.02.032  0.432
2010 Shen L, Kim S, Risacher SL, Nho K, Swaminathan S, West JD, Foroud T, Pankratz N, Moore JH, Sloan CD, Huentelman MJ, Craig DW, Dechairo BM, Potkin SG, Jack CR, et al. Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. Neuroimage. 53: 1051-63. PMID 20100581 DOI: 10.1016/J.Neuroimage.2010.01.042  0.445
2010 Risacher SL, Saykin AJ, Pepin SM, WuDunn D, MaGee TR, McDonald BC, Shen L, West JD, Englert JJ, Flashman LA, Pixley HS, Curtain JR, Wishart HA, O'Neill DP, Santulli RB, et al. P3-224: Visual contrast sensitivity as a novel biomarker for neurodegeneration in early Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints Alzheimer's & Dementia. 6: S516-S517. DOI: 10.1016/J.Jalz.2010.05.1723  0.306
2010 Saykin AJ, Yoder KK, Risacher SL, MaGee TR, McDonald BC, Zheng Q, Wang M, Mock BH, Shen L, West JD, Fletcher JW, Farlow MR, Hutchins GD. IC-01-04: Neuroinflammation and amyloid deposition: Concurrent [11 C]PBR28 and [11 C]PIB PET imaging in patients with Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints Alzheimer's & Dementia. 6: S3-S4. DOI: 10.1016/J.Jalz.2010.05.010  0.316
2009 Kim S, Shen L, Saykin AJ, West JD. Data Synthesis and Tool Development for Exploring Imaging Genomic Patterns. Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology Proceedings Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. 2009: 298-305. PMID 21461341 DOI: 10.1109/CIBCB.2009.4925742  0.302
2009 Kim S, Shen L, Saykin AJ, West JD. Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 3849-52. PMID 19963597 DOI: 10.1109/IEMBS.2009.5332570  0.311
2009 Risacher SL, Saykin AJ, West JD, Shen L, Firpi HA, McDonald BC. Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort. Current Alzheimer Research. 6: 347-61. PMID 19689234 DOI: 10.2174/156720509788929273  0.366
2009 Shen L, Firpi HA, Saykin AJ, West JD. Parametric surface modeling and registration for comparison of manual and automated segmentation of the hippocampus. Hippocampus. 19: 588-95. PMID 19405146 DOI: 10.1002/Hipo.20613  0.348
2009 Shen L, Kim S, West J, Saykin A. Building an Imaging Genomic Browsing System for Examining Genetic Effects on Brain Neuroimage. 47: S140. DOI: 10.1016/S1053-8119(09)71391-6  0.376
2009 Saykin AJ, Shen L, Risacher SL, Kim S, Nho K, West JD, M. Foroud T. IC-O1-01: Genetic predictors of 12-month change in MRI hippocampal volume in the Alzheimer's Disease Neuroimaging Initiative cohort: Analysis of leading candidates from the AlzGene database Alzheimer's & Dementia. 5: P3-P3. DOI: 10.1016/J.Jalz.2009.05.011  0.423
2008 Saykin AJ, West JD, Shen L, Firpi HA, Wessels A, Cannon A, Risacher S, McDonald BC. P2-072: Hippocampal and distributed gray matter abnormalities in mild cognitive impairment and early Alzheimer's disease in the Alzheimer's disease neuroimaging initiative baseline 1.5T MRI scans: Cross-sectional analysis and relation to verbal learning Alzheimer's & Dementia. 4: T388-T389. DOI: 10.1016/J.Jalz.2008.05.1145  0.352
2007 McHugh TL, Saykin AJ, Wishart HA, Flashman LA, Cleavinger HB, Rabin LA, Mamourian AC, Shen L. Hippocampal volume and shape analysis in an older adult population. The Clinical Neuropsychologist. 21: 130-45. PMID 17366281 DOI: 10.1080/13854040601064534  0.332
2005 Shen L, Saykin A, McHugh T, West J, Rabin L, Wishart H, Chung MK, Makedon F. [P-120]: Morphometric MRI study of hippocampal shape in MCI using spherical harmonics Alzheimer's & Dementia. 1: S47-S47. DOI: 10.1016/J.Jalz.2005.06.193  0.345
2000 Megalooikonomou V, Ford J, Shen L, Makedon F, Saykin A. Data mining in brain imaging Statistical Methods in Medical Research. 9: 359-394. PMID 11084713 DOI: 10.1177/096228020000900404  0.361
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