Marjorie Oettinger - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lion M, Muhire B, Namiki Y, Tolstorukov MY, Oettinger MA. Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 117: 5453-5462. PMID 32098847 DOI: 10.1073/pnas.1914923117  0.394
2019 Ciccone DN, Namiki Y, Chen C, Morshead KB, Wood AL, Johnston CM, Morris JW, Wang Y, Sadreyev R, Corcoran AE, Matthews AGW, Oettinger MA. The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF. The Journal of Biological Chemistry. PMID 31285261 DOI: 10.1074/Jbc.Ra118.007348  0.734
2016 Pulivarthy SR, Lion M, Kuzu G, Matthews AG, Borowsky ML, Morris J, Kingston RE, Dennis JH, Tolstorukov MY, Oettinger MA. Regulated large-scale nucleosome density patterns and precise nucleosome positioning correlate with V(D)J recombination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698124 DOI: 10.1073/Pnas.1605543113  0.42
2012 Yuan CC, Matthews AG, Jin Y, Chen CF, Chapman BA, Ohsumi TK, Glass KC, Kutateladze TG, Borowsky ML, Struhl K, Oettinger MA. Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes. Cell Reports. 1: 83-90. PMID 22720264 DOI: 10.1016/J.Celrep.2011.12.008  0.416
2012 Balter BB, Ciccone DN, Oettinger MA, Selsing E. Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations. Molecular Immunology. 52: 1-8. PMID 22580346 DOI: 10.1016/J.Molimm.2012.04.006  0.775
2009 Matthews AG, Oettinger MA. Regulation of RAG transposition. Advances in Experimental Medicine and Biology. 650: 16-31. PMID 19731798  0.376
2009 Matthews AG, Oettinger MA. RAG: a recombinase diversified. Nature Immunology. 10: 817-21. PMID 19621044 DOI: 10.1038/ni.1776  0.371
2007 Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, ... ... Oettinger MA, et al. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 450: 1106-10. PMID 18033247 DOI: 10.1038/Nature06431  0.813
2007 Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proceedings of the National Academy of Sciences of the United States of America. 104: 18993-8. PMID 18025461 DOI: 10.1073/Pnas.0709170104  0.405
2005 Elkin SK, Ivanov D, Ewalt M, Ferguson CG, Hyberts SG, Sun ZY, Prestwich GD, Yuan J, Wagner G, Oettinger MA, Gozani OP. A PHD finger motif in the C terminus of RAG2 modulates recombination activity. The Journal of Biological Chemistry. 280: 28701-10. PMID 15964836 DOI: 10.1074/Jbc.M504731200  0.307
2005 Dai Y, Wong B, Yen YM, Oettinger MA, Kwon J, Johnson RC. Determinants of HMGB proteins required to promote RAG1/2-recombination signal sequence complex assembly and catalysis during V(D)J recombination. Molecular and Cellular Biology. 25: 4413-25. PMID 15899848 DOI: 10.1128/Mcb.25.11.4413-4425.2005  0.423
2005 Clatworthy AE, Valencia-Burton MA, Haber JE, Oettinger MA. The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast Journal of Biological Chemistry. 280: 20247-20252. PMID 15757898 DOI: 10.1074/Jbc.M500126200  0.745
2004 Oettinger MA. How to keep V(D)J recombination under control. Immunological Reviews. 200: 165-81. PMID 15242404 DOI: 10.1111/j.0105-2896.2004.00172.x  0.332
2004 Patenge N, Elkin SK, Oettinger MA. ATP-dependent remodeling by SWI/SNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays. The Journal of Biological Chemistry. 279: 35360-7. PMID 15201272 DOI: 10.1074/jbc.M405790200  0.435
2004 Ciccone D, Oettinger M. Chromatin modifications as clues to the regulation of antigen receptor assembly. Novartis Foundation Symposium. 259: 146-58; discussion 1. PMID 15171252 DOI: 10.1002/0470862637.Ch10  0.811
2004 Matthews AG, Elkin SK, Oettinger MA. Ordered DNA release and target capture in RAG transposition. The Embo Journal. 23: 1198-206. PMID 14988730 DOI: 10.1038/sj.emboj.7600131  0.338
2004 Ciccone DN, Morshead KB, Oettinger MA. Chromatin immunoprecipitation in the analysis of large chromatin domains across murine antigen receptor loci. Methods in Enzymology. 376: 334-48. PMID 14975316 DOI: 10.1016/S0076-6879(03)76022-4  0.753
2003 Park EJ, Chan DW, Park JH, Oettinger MA, Kwon J. DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner. Nucleic Acids Research. 31: 6819-27. PMID 14627815  0.327
2003 Clatworthy AE, Valencia MA, Haber JE, Oettinger MA. V(D)J recombination and RAG-mediated transposition in yeast Molecular Cell. 12: 489-499. PMID 14536087 DOI: 10.1016/S1097-2765(03)00305-8  0.76
2003 Morshead KB, Ciccone DN, Taverna SD, Allis CD, Oettinger MA. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proceedings of the National Academy of Sciences of the United States of America. 100: 11577-82. PMID 14500909 DOI: 10.1073/Pnas.1932643100  0.762
2003 Elkin SK, Matthews AG, Oettinger MA. The C-terminal portion of RAG2 protects against transposition in vitro. The Embo Journal. 22: 1931-8. PMID 12682025 DOI: 10.1093/emboj/cdg184  0.414
2003 Dai Y, Kysela B, Hanakahi LA, Manolis K, Riballo E, Stumm M, Harville TO, West SC, Oettinger MA, Jeggo PA. Nonhomologous end joining and V(D)J recombination require an additional factor. Proceedings of the National Academy of Sciences of the United States of America. 100: 2462-7. PMID 12604777 DOI: 10.1073/Pnas.0437964100  0.371
2003 Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K. Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation. Proceedings of the National Academy of Sciences of the United States of America. 100: 1820-5. PMID 12574507 DOI: 10.1073/Pnas.0437846100  0.739
2003 Akamatsu Y, Monroe R, Dudley DD, Elkin SK, Gartner F, Talukder SR, Takahama Y, Alt FW, Bassing CH, Oettinger MA. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 1209-14. PMID 12531919 DOI: 10.1073/Pnas.0237043100  0.327
2002 Mundy CL, Patenge N, Matthews AG, Oettinger MA. Assembly of the RAG1/RAG2 synaptic complex. Molecular and Cellular Biology. 22: 69-77. PMID 11739723 DOI: 10.1128/Mcb.22.1.69-77.2002  0.786
2001 Baldwin AS, Oettinger M, Struhl K. Methylation and uracil interference assays for analysis of protein-DNA interactions. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 12.3. PMID 18265086 DOI: 10.1002/0471142727.Mb1203S36  0.442
2001 Riballo E, Doherty AJ, Dai Y, Stiff T, Oettinger MA, Jeggo PA, Kysela B. Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity. The Journal of Biological Chemistry. 276: 31124-32. PMID 11349135 DOI: 10.1074/Jbc.M103866200  0.3
2000 Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Molecular Cell. 6: 1037-48. PMID 11106743 DOI: 10.1016/S1097-2765(00)00102-7  0.802
1999 Kim DR, Dai Y, Mundy CL, Yang W, Oettinger MA. Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase. Genes & Development. 13: 3070-80. PMID 10601033 DOI: 10.1101/Gad.13.23.3070  0.775
1999 Oettinger MA. V(D)J recombination: on the cutting edge. Current Opinion in Cell Biology. 11: 325-9. PMID 10395566 DOI: 10.1016/S0955-0674(99)80044-1  0.324
1999 Steen SB, Han JO, Mundy C, Oettinger MA, Roth DB. Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination. Molecular and Cellular Biology. 19: 3010-7. PMID 10082568 DOI: 10.1128/Mcb.19.4.3010  0.791
1999 Kwon J, Imbalzano AN, Matthews A, Oettinger MA. Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1. Molecular Cell. 2: 829-39. PMID 9885570 DOI: 10.1016/S1097-2765(00)80297-X  0.474
1998 Kirch SA, Rathbun GA, Oettinger MA. Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly. The Embo Journal. 17: 4881-6. PMID 9707447 DOI: 10.1093/EMBOJ/17.16.4881  0.377
1998 Akamatsu Y, Oettinger MA. Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences. Molecular and Cellular Biology. 18: 4670-8. PMID 9671477 DOI: 10.1128/MCB.18.8.4670  0.395
1996 Cuomo CA, Mundy CL, Oettinger MA. DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences. Molecular and Cellular Biology. 16: 5683-90. PMID 8816481 DOI: 10.1128/Mcb.16.10.5683  0.781
1996 Kirch SA, Sudarsanam P, Oettinger MA. Regions of RAG1 protein critical for V(D)J recombination. European Journal of Immunology. 26: 886-91. PMID 8625984 DOI: 10.1002/eji.1830260425  0.332
1996 McBlane JF, van Gent DC, Ramsden DA, Romeo C, Cuomo CA, Gellert M, Oettinger MA. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell. 83: 387-95. PMID 8521468 DOI: 10.1016/0092-8674(95)90116-7  0.333
1996 Gallay P, Stitt V, Mundy C, Oettinger M, Trono D. Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import. Journal of Virology. 70: 1027-1032. DOI: 10.1128/Jvi.70.2.1027-1032.1996  0.735
1995 Kirchgessner CU, Patil CK, Evans JW, Cuomo CA, Fried LM, Carter T, Oettinger MA, Brown JM. DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science (New York, N.Y.). 267: 1178-83. PMID 7855601 DOI: 10.1126/Science.7855601  0.365
1994 Cuomo CA, Oettinger MA. Analysis of regions of RAG-2 important for V(D)J recombination. Nucleic Acids Research. 22: 1810-4. PMID 8208604 DOI: 10.1093/nar/22.10.1810  0.346
1994 Cuomo CA, Kirch SA, Gyuris J, Brent R, Oettinger MA. Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 6156-60. PMID 8016130 DOI: 10.1073/Pnas.91.13.6156  0.312
1992 Schatz DG, Oettinger MA, Schlissel MS. V(D)J recombination: molecular biology and regulation. Annual Review of Immunology. 10: 359-83. PMID 1590991 DOI: 10.1146/Annurev.Iy.10.040192.002043  0.332
1991 Hendrickson EA, Qin XQ, Bump EA, Schatz DG, Oettinger M, Weaver DT. A link between double-strand break-related repair and V(D)J recombination: the scid mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 4061-5. PMID 1709732 DOI: 10.1073/Pnas.88.10.4061  0.407
1990 Oettinger MA, Schatz DG, Gorka C, Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science (New York, N.Y.). 248: 1517-23. PMID 2360047 DOI: 10.1126/Science.2360047  0.355
1989 Schatz DG, Oettinger MA, Baltimore D. The V(D)J recombination activating gene, RAG-1. Cell. 59: 1035-48. PMID 2598259 DOI: 10.1016/0092-8674(89)90760-5  0.315
1986 Struhl K, Chen W, Hill DE, Hope IA, Oettinger MA. Constitutive and coordinately regulated transcription of yeast genes: promoter elements, positive and negative regulatory sites, and DNA binding proteins. Cold Spring Harbor Symposia On Quantitative Biology. 50: 489-503. PMID 3913566 DOI: 10.1101/Sqb.1985.050.01.061  0.311
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