| Year |
Citation |
Score |
| 2023 |
Balasooriya GI, Wee TL, Spector DL. A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region. Biorxiv : the Preprint Server For Biology. PMID 37961255 DOI: 10.1101/2023.10.28.564411 |
0.326 |
|
| 2023 |
Hazra R, Utama R, Naik P, Dobin A, Spector DL. Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA sequencing datasets. Stem Cell Reports. PMID 37922916 DOI: 10.1016/j.stemcr.2023.10.004 |
0.835 |
|
| 2023 |
Aggarwal D, Russo S, Naik P, Bhatia S, Spector DL. Establishment and Culture of Patient-Derived Breast Organoids. Journal of Visualized Experiments : Jove. PMID 36876940 DOI: 10.3791/64889 |
0.72 |
|
| 2023 |
Hazra R, Utama R, Naik P, Dobin A, Spector DL. Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets. Biorxiv : the Preprint Server For Biology. PMID 36711961 DOI: 10.1101/2023.01.20.524887 |
0.839 |
|
| 2023 |
Mattick JS, Amaral PP, Carninci P, Carpenter S, Chang HY, Chen LL, Chen R, Dean C, Dinger ME, Fitzgerald KA, Gingeras TR, Guttman M, Hirose T, Huarte M, Johnson R, ... ... Spector DL, et al. Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews. Molecular Cell Biology. PMID 36596869 DOI: 10.1038/s41580-022-00566-8 |
0.756 |
|
| 2022 |
Yu AT, Aggarwal D, Pappin D, Spector DL. Single Oligonucleotide Capture of RNA And Temperature Elution Series ( ) for Identification of RNA-binding Proteins. Bio-Protocol. 12. PMID 36618090 DOI: 10.21769/BioProtoc.4572 |
0.737 |
|
| 2022 |
Moravec JC, Lanfear R, Spector DL, Diermeier SD, Gavryushkin A. Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. PMID 36475926 DOI: 10.1089/cmb.2022.0357 |
0.753 |
|
| 2022 |
Hazra R, Brine L, Garcia L, Benz B, Chirathivat N, Shen MM, Wilkinson JE, Lyons SK, Spector DL. Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment. Developmental Cell. 57: 2450-2468.e7. PMID 36347239 DOI: 10.1016/j.devcel.2022.10.002 |
0.81 |
|
| 2022 |
Hazra R, Spector DL. Simultaneous visualization of RNA transcripts and proteins in whole-mount mouse preimplantation embryos using single-molecule fluorescence hybridization and immunofluorescence microscopy. Frontiers in Cell and Developmental Biology. 10: 986261. PMID 36268512 DOI: 10.3389/fcell.2022.986261 |
0.829 |
|
| 2022 |
Bhatia S, Kramer M, Russo S, Naik P, Arun G, Brophy K, Andrews P, Fan C, Perou CM, Preall J, Ha T, Plenker D, Tuveson DA, Rishi A, Wilkinson JE, ... ... Spector DL, et al. Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. PMID 35180770 DOI: 10.1158/0008-5472.CAN-21-2807 |
0.778 |
|
| 2021 |
Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, et al. Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34791665 DOI: 10.1111/nyas.14713 |
0.827 |
|
| 2021 |
Yu AT, Berasain C, Bhatia S, Rivera K, Liu B, Rigo F, Pappin DJ, Spector DL. lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR. Elife. 10. PMID 34002693 DOI: 10.7554/eLife.68263 |
0.833 |
|
| 2021 |
Chang KC, Spector DL. : a long non-coding RNA involved in breast cancer progression. Molecular & Cellular Oncology. 8: 1882286. PMID 33860086 DOI: 10.1080/23723556.2021.1882286 |
0.817 |
|
| 2020 |
Chang KC, Diermeier SD, Yu AT, Brine LD, Russo S, Bhatia S, Alsudani H, Kostroff K, Bhuiya T, Brogi E, Pappin DJ, Bennett CF, Rigo F, Spector DL. MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression. Nature Communications. 11: 6438. PMID 33353933 DOI: 10.1038/s41467-020-20207-y |
0.819 |
|
| 2020 |
Aganezov S, Goodwin S, Sherman RM, Sedlazeck FJ, Arun G, Bhatia S, Lee I, Kirsche M, Wappel R, Kramer M, Kostroff K, Spector DL, Timp W, McCombie WR, Schatz MC. Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing. Genome Research. PMID 32887686 DOI: 10.1101/Gr.260497.119 |
0.776 |
|
| 2020 |
Arun G, Aggarwal D, Spector DL. Long Non-Coding RNA: Functional Implications. Non-Coding Rna. 6. PMID 32503170 DOI: 10.3390/Ncrna6020022 |
0.844 |
|
| 2019 |
Arun G, Spector DL. MALAT1 long non-coding RNA and breast cancer. Rna Biology. 1-4. PMID 30874469 DOI: 10.1080/15476286.2019.1592072 |
0.825 |
|
| 2019 |
Abulwerdi FA, Xu W, Ageeli AA, Yonkunas MJ, Arun G, Nam H, Schneekloth JS, Dayie TK, Spector D, Baird N, Le Grice SFJ. Selective small molecule targeting of a triple helix encoded by the long non-coding RNA, MALAT1. Acs Chemical Biology. PMID 30620551 DOI: 10.1021/Acschembio.8B00807 |
0.842 |
|
| 2018 |
Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR. POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes & Development. PMID 29945888 DOI: 10.1101/Gad.314815.118 |
0.816 |
|
| 2018 |
Arun G, Diermeier SD, Spector DL. Therapeutic Targeting of Long Non-Coding RNAs in Cancer. Trends in Molecular Medicine. PMID 29449148 DOI: 10.1016/J.Molmed.2018.01.001 |
0.815 |
|
| 2017 |
Diermeier SD, Spector DL. Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids. Bio-Protocol. 7. PMID 28932764 DOI: 10.21769/BioProtoc.2511 |
0.717 |
|
| 2017 |
Li MA, Amaral PP, Cheung P, Bergmann JH, Kinoshita M, Kalkan T, Ralser M, Robson S, Meyenn FV, Paramor M, Yang F, Chen C, Nichols J, Spector DL, Kouzarides T, et al. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation. Elife. 6. PMID 28820723 DOI: 10.7554/Elife.23468 |
0.746 |
|
| 2017 |
Zhang B, Mao YS, Diermeier SD, Novikova IV, Nawrocki EP, Jones TA, Lazar Z, Tung CS, Luo W, Eddy SR, Sanbonmatsu KY, Spector DL. Identification and Characterization of a Class of MALAT1-like Genomic Loci. Cell Reports. 19: 1723-1738. PMID 28538188 DOI: 10.1016/J.Celrep.2017.05.006 |
0.836 |
|
| 2016 |
Diermeier SD, Chang KC, Freier SM, Song J, El Demerdash O, Krasnitz A, Rigo F, Bennett CF, Spector DL. Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration. Cell Reports. 17: 261-74. PMID 27681436 DOI: 10.1016/J.Celrep.2016.08.081 |
0.823 |
|
| 2016 |
Arun G, Diermeier S, Akerman M, Chang K, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL. Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Pr11 |
0.452 |
|
| 2016 |
Diermeier SD, Chang K, Freier SM, Rigo F, Bennett CF, Spector DL. Abstract A43: Long noncoding RNAs as targets of mammary tumor cell proliferation and migration Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A43 |
0.507 |
|
| 2015 |
Arun G, Diermeier S, Akerman M, Chang KC, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL. Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes & Development. PMID 26701265 DOI: 10.1101/Gad.270959.115 |
0.803 |
|
| 2015 |
Zepeda-Mendoza CJ, Mukhopadhyay S, Wong ES, Harder N, Splinter E, de Wit E, Eckersley-Maslin MA, Ried T, Eils R, Rohr K, Mills A, de Laat W, Flicek P, Sengupta AM, Spector DL. Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2. Bmc Genomics. 16: 982. PMID 26589460 DOI: 10.1186/S12864-015-2137-5 |
0.787 |
|
| 2015 |
Bergmann JH, Li J, Eckersley-Maslin MA, Rigo F, Freier SM, Spector DL. Regulation of the ESC transcriptome by nuclear long noncoding RNAs. Genome Research. PMID 26048247 DOI: 10.1101/Gr.189027.114 |
0.843 |
|
| 2015 |
Hogan MS, Parfitt DE, Zepeda-Mendoza CJ, Shen MM, Spector DL. Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation. Cell Stem Cell. 16: 275-88. PMID 25748933 DOI: 10.1016/J.Stem.2015.02.001 |
0.758 |
|
| 2014 |
Eckersley-Maslin MA, Spector DL. Random monoallelic expression: regulating gene expression one allele at a time. Trends in Genetics : Tig. 30: 237-44. PMID 24780084 DOI: 10.1016/J.Tig.2014.03.003 |
0.774 |
|
| 2014 |
Bell RD, Long X, Lin M, Bergmann JH, Nanda V, Cowan SL, Zhou Q, Han Y, Spector DL, Zheng D, Miano JM. Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1249-59. PMID 24578380 DOI: 10.1161/Atvbaha.114.303240 |
0.766 |
|
| 2014 |
Eckersley-Maslin MA, Thybert D, Bergmann JH, Marioni JC, Flicek P, Spector DL. Random monoallelic gene expression increases upon embryonic stem cell differentiation. Developmental Cell. 28: 351-65. PMID 24576421 DOI: 10.1016/J.Devcel.2014.01.017 |
0.815 |
|
| 2014 |
Bergmann JH, Spector DL. Long non-coding RNAs: modulators of nuclear structure and function. Current Opinion in Cell Biology. 26: 10-8. PMID 24529241 DOI: 10.1016/J.Ceb.2013.08.005 |
0.77 |
|
| 2013 |
Dowen JM, Bilodeau S, Orlando DA, Hübner MR, Abraham BJ, Spector DL, Young RA. Multiple structural maintenance of chromosome complexes at transcriptional regulatory elements. Stem Cell Reports. 1: 371-8. PMID 24286025 DOI: 10.1016/J.Stemcr.2013.09.002 |
0.374 |
|
| 2013 |
Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, ... ... Spector DL, et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes & Development. 27: 2648-62. PMID 24285714 DOI: 10.1101/Gad.232710.113 |
0.821 |
|
| 2013 |
Chen Z, Jaafar L, Agyekum DG, Xiao H, Wade MF, Kumaran RI, Spector DL, Bao G, Porteus MH, Dynan WS, Meiler SE. Receptor-mediated delivery of engineered nucleases for genome modification. Nucleic Acids Research. 41: e182. PMID 23956220 DOI: 10.1093/Nar/Gkt710 |
0.348 |
|
| 2013 |
Bodnar MS, Spector DL. Chromatin meets its organizers. Cell. 153: 1187-9. PMID 23746835 DOI: 10.1016/J.Cell.2013.05.030 |
0.346 |
|
| 2013 |
Eckersley-Maslin MA, Bergmann JH, Lazar Z, Spector DL. Lamin A/C is expressed in pluripotent mouse embryonic stem cells. Nucleus (Austin, Tex.). 4: 53-60. PMID 23324457 DOI: 10.4161/Nucl.23384 |
0.812 |
|
| 2013 |
Hübner MR, Eckersley-Maslin MA, Spector DL. Chromatin organization and transcriptional regulation. Current Opinion in Genetics & Development. 23: 89-95. PMID 23270812 DOI: 10.1016/J.Gde.2012.11.006 |
0.779 |
|
| 2013 |
Gutschner T, Hämmerle M, Eissmann M, Hsu J, Kim Y, Hung G, Revenko A, Arun G, Stentrup M, Gross M, Zörnig M, MacLeod AR, Spector DL, Diederichs S. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Research. 73: 1180-9. PMID 23243023 DOI: 10.1158/0008-5472.Can-12-2850 |
0.828 |
|
| 2013 |
Gutschner T, Hämmerle M, Eißmann M, Hsu J, Kim Y, Hung G, Revenko A, Arun G, Stentrup M, Groß M, Zörnig M, MacLeod AR, Spector DL, Diederichs S. Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model . Cancer Research. 73: 1121-1121. DOI: 10.1158/1538-7445.Am2013-1121 |
0.446 |
|
| 2012 |
Zhang B, Arun G, Mao YS, Lazar Z, Hung G, Bhattacharjee G, Xiao X, Booth CJ, Wu J, Zhang C, Spector DL. The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Reports. 2: 111-23. PMID 22840402 DOI: 10.1016/J.Celrep.2012.06.003 |
0.83 |
|
| 2011 |
Zhao R, Nakamura T, Fu Y, Lazar Z, Spector DL. Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nature Cell Biology. 13: 1295-304. PMID 21983563 DOI: 10.1038/Ncb2341 |
0.567 |
|
| 2011 |
Spector DL. Immunofluorescence localization of nuclear proteins. Cold Spring Harbor Protocols. 2011: 1276-80. PMID 21969615 DOI: 10.1101/Pdb.Prot065755 |
0.378 |
|
| 2011 |
Mao YS, Zhang B, Spector DL. Biogenesis and function of nuclear bodies. Trends in Genetics : Tig. 27: 295-306. PMID 21680045 DOI: 10.1016/J.Tig.2011.05.006 |
0.809 |
|
| 2011 |
Shi L, Wang J, Hong F, Spector DL, Fang Y. Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 10574-8. PMID 21670303 DOI: 10.1073/Pnas.1017882108 |
0.694 |
|
| 2011 |
Mao YS, Sunwoo H, Zhang B, Spector DL. Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs. Nature Cell Biology. 13: 95-101. PMID 21170033 DOI: 10.1038/Ncb2140 |
0.808 |
|
| 2011 |
Meiler SE, Dynan WS, Porteus M, Spector DL, Bao G, Chen Z, Pandey J, Goyal D, Kumaran RI, Wade M, Agyekum D. A Biological Delivery Platform for Zinc Finger Nucleases Using Transferrin-Mediated Endocytosis Blood. 118: 1071-1071. DOI: 10.1182/Blood.V118.21.1071.1071 |
0.388 |
|
| 2010 |
Hübner MR, Spector DL. Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. Cold Spring Harbor Symposia On Quantitative Biology. 75: 43-9. PMID 21209387 DOI: 10.1101/Sqb.2010.75.020 |
0.409 |
|
| 2010 |
Spector DL, Goldman RD. Constructing and expressing fluorescent protein fusions. Cold Spring Harbor Protocols. 2010: pdb.top87. PMID 21041402 DOI: 10.1101/Pdb.Top87 |
0.312 |
|
| 2010 |
Spector DL, Goldman RD. Transfection of mammalian cells with fluorescent protein fusions. Cold Spring Harbor Protocols. 2010: pdb.prot5517. PMID 21041390 DOI: 10.1101/Pdb.Prot5517 |
0.359 |
|
| 2010 |
Prasanth KV, Camiolo M, Chan G, Tripathi V, Denis L, Nakamura T, Hübner MR, Spector DL. Nuclear organization and dynamics of 7SK RNA in regulating gene expression. Molecular Biology of the Cell. 21: 4184-96. PMID 20881057 DOI: 10.1091/Mbc.E10-02-0105 |
0.836 |
|
| 2010 |
Bernard D, Prasanth KV, Tripathi V, Colasse S, Nakamura T, Xuan Z, Zhang MQ, Sedel F, Jourdren L, Coulpier F, Triller A, Spector DL, Bessis A. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. The Embo Journal. 29: 3082-93. PMID 20729808 DOI: 10.1038/Emboj.2010.199 |
0.729 |
|
| 2010 |
Hübner MR, Spector DL. Chromatin dynamics. Annual Review of Biophysics. 39: 471-89. PMID 20462379 DOI: 10.1146/annurev.biophys.093008.131348 |
0.309 |
|
| 2010 |
Ben-Ari Y, Brody Y, Kinor N, Mor A, Tsukamoto T, Spector DL, Singer RH, Shav-Tal Y. The life of an mRNA in space and time. Journal of Cell Science. 123: 1761-74. PMID 20427315 DOI: 10.1242/Jcs.062638 |
0.438 |
|
| 2010 |
Fang Y, Spector DL. Live cell imaging of plants. Cold Spring Harbor Protocols. 2010: pdb.top68. PMID 20150164 DOI: 10.1101/Pdb.Top68 |
0.697 |
|
| 2010 |
Fang Y, Spector DL. Four-dimensional imaging of plant cells during the cell cycle. Cold Spring Harbor Protocols. 2010: pdb.prot5381. PMID 20150144 DOI: 10.1101/Pdb.Prot5381 |
0.686 |
|
| 2010 |
Fang Y, Spector DL. BiFC imaging assay for plant protein-protein interactions. Cold Spring Harbor Protocols. 2010: pdb.prot5380. PMID 20150143 DOI: 10.1101/Pdb.Prot5380 |
0.679 |
|
| 2010 |
Wilusz JE, Spector DL. An unexpected ending: noncanonical 3' end processing mechanisms. Rna (New York, N.Y.). 16: 259-66. PMID 20007330 DOI: 10.1261/Rna.1907510 |
0.748 |
|
| 2009 |
Wilusz JE, Sunwoo H, Spector DL. Long noncoding RNAs: functional surprises from the RNA world. Genes & Development. 23: 1494-504. PMID 19571179 DOI: 10.1101/Gad.1800909 |
0.84 |
|
| 2009 |
Zhao R, Bodnar MS, Spector DL. Nuclear neighborhoods and gene expression. Current Opinion in Genetics & Development. 19: 172-9. PMID 19339170 DOI: 10.1016/J.Gde.2009.02.007 |
0.51 |
|
| 2009 |
Sunwoo H, Dinger ME, Wilusz JE, Amaral PP, Mattick JS, Spector DL. MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Research. 19: 347-59. PMID 19106332 DOI: 10.1101/Gr.087775.108 |
0.814 |
|
| 2008 |
Wilusz JE, Freier SM, Spector DL. 3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell. 135: 919-32. PMID 19041754 DOI: 10.1016/J.Cell.2008.10.012 |
0.756 |
|
| 2008 |
Dimitrova N, Chen YC, Spector DL, de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature. 456: 524-8. PMID 18931659 DOI: 10.1038/Nature07433 |
0.307 |
|
| 2008 |
Chen YC, Kappel C, Beaudouin J, Eils R, Spector DL. Live cell dynamics of promyelocytic leukemia nuclear bodies upon entry into and exit from mitosis. Molecular Biology of the Cell. 19: 3147-62. PMID 18480407 DOI: 10.1091/Mbc.E08-01-0035 |
0.393 |
|
| 2008 |
Rosin FM, Watanabe N, Cacas JL, Kato N, Arroyo JM, Fang Y, May B, Vaughn M, Simorowski J, Ramu U, McCombie RW, Spector DL, Martienssen RA, Lam E. Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 55: 514-25. PMID 18410481 DOI: 10.1111/J.1365-313X.2008.03517.X |
0.749 |
|
| 2008 |
Kumaran RI, Thakar R, Spector DL. Chromatin dynamics and gene positioning. Cell. 132: 929-34. PMID 18358806 DOI: 10.1016/J.Cell.2008.03.004 |
0.795 |
|
| 2008 |
Kumaran RI, Spector DL. A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence. The Journal of Cell Biology. 180: 51-65. PMID 18195101 DOI: 10.1083/Jcb.200706060 |
0.445 |
|
| 2007 |
Fang Y, Spector DL. Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants. Current Biology : Cb. 17: 818-23. PMID 17442570 DOI: 10.1016/J.Cub.2007.04.005 |
0.703 |
|
| 2007 |
Prasanth KV, Spector DL. Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrum. Genes & Development. 21: 11-42. PMID 17210785 DOI: 10.1101/Gad.1484207 |
0.722 |
|
| 2007 |
Spector DL. NUCLEAR RETAINED RNAs REGULATING GENE EXPRESSION The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A97 |
0.525 |
|
| 2006 |
Spector DL, Goldman RD. Constructing and Expressing GFP Fusion Proteins. Csh Protocols. 2006. PMID 22484672 DOI: 10.1101/Pdb.Prot4649 |
0.344 |
|
| 2006 |
Lee H, Quinn JC, Prasanth KV, Swiss VA, Economides KD, Camacho MM, Spector DL, Abate-Shen C. PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. Genes & Development. 20: 784-94. PMID 16600910 DOI: 10.1101/Gad.1392006 |
0.661 |
|
| 2006 |
Politz JC, Tuft RA, Prasanth KV, Baudendistel N, Fogarty KE, Lifshitz LM, Langowski J, Spector DL, Pederson T. Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm. Molecular Biology of the Cell. 17: 1239-49. PMID 16371503 DOI: 10.1091/Mbc.E05-10-0952 |
0.715 |
|
| 2005 |
May BP, Lippman ZB, Fang Y, Spector DL, Martienssen RA. Differential regulation of strand-specific transcripts from Arabidopsis centromeric satellite repeats. Plos Genetics. 1: e79. PMID 16389298 DOI: 10.1371/Journal.Pgen.0010079 |
0.763 |
|
| 2005 |
Prasanth KV, Prasanth SG, Xuan Z, Hearn S, Freier SM, Bennett CF, Zhang MQ, Spector DL. Regulating gene expression through RNA nuclear retention. Cell. 123: 249-63. PMID 16239143 DOI: 10.1016/J.Cell.2005.08.033 |
0.744 |
|
| 2005 |
Fang Y, Spector DL. Centromere positioning and dynamics in living Arabidopsis plants. Molecular Biology of the Cell. 16: 5710-8. PMID 16195344 DOI: 10.1091/Mbc.E05-08-0706 |
0.732 |
|
| 2004 |
Bubulya PA, Prasanth KV, Deerinck TJ, Gerlich D, Beaudouin J, Ellisman MH, Ellenberg J, Spector DL. Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. The Journal of Cell Biology. 167: 51-63. PMID 15479736 DOI: 10.1083/Jcb.200404120 |
0.81 |
|
| 2004 |
Prasanth SG, Prasanth KV, Siddiqui K, Spector DL, Stillman B. Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance. The Embo Journal. 23: 2651-63. PMID 15215892 DOI: 10.1038/sj.emboj.7600255 |
0.636 |
|
| 2004 |
Shav-Tal Y, Darzacq X, Shenoy SM, Fusco D, Janicki SM, Spector DL, Singer RH. Dynamics of single mRNPs in nuclei of living cells. Science (New York, N.Y.). 304: 1797-800. PMID 15205532 DOI: 10.1126/Science.1099754 |
0.785 |
|
| 2004 |
Saitoh N, Spahr CS, Patterson SD, Bubulya P, Neuwald AF, Spector DL. Proteomic analysis of interchromatin granule clusters. Molecular Biology of the Cell. 15: 3876-90. PMID 15169873 DOI: 10.1091/Mbc.E04-03-0253 |
0.803 |
|
| 2004 |
Ono T, Fang Y, Spector DL, Hirano T. Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells. Molecular Biology of the Cell. 15: 3296-308. PMID 15146063 DOI: 10.1091/Mbc.E04-03-0242 |
0.699 |
|
| 2004 |
Bubulya PA, Spector DL. "On the move"ments of nuclear components in living cells. Experimental Cell Research. 296: 4-11. PMID 15120987 DOI: 10.1016/J.Yexcr.2004.03.018 |
0.786 |
|
| 2004 |
Fang Y, Hearn S, Spector DL. Tissue-specific expression and dynamic organization of SR splicing factors in Arabidopsis. Molecular Biology of the Cell. 15: 2664-73. PMID 15034145 DOI: 10.1091/Mbc.E04-02-0100 |
0.741 |
|
| 2004 |
Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL. From silencing to gene expression: real-time analysis in single cells. Cell. 116: 683-98. PMID 15006351 DOI: 10.1016/S0092-8674(04)00171-0 |
0.829 |
|
| 2003 |
Spector DL. The dynamics of chromosome organization and gene regulation. Annual Review of Biochemistry. 72: 573-608. PMID 14527325 DOI: 10.1146/Annurev.Biochem.72.121801.161724 |
0.425 |
|
| 2003 |
Lamond AI, Spector DL. Nuclear speckles: a model for nuclear organelles. Nature Reviews. Molecular Cell Biology. 4: 605-12. PMID 12923522 DOI: 10.1038/Nrm1172 |
0.481 |
|
| 2003 |
Narita M, N?nez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell. 113: 703-16. PMID 12809602 DOI: 10.1016/S0092-8674(03)00401-X |
0.416 |
|
| 2003 |
Janicki SM, Spector DL. Nuclear choreography: interpretations from living cells. Current Opinion in Cell Biology. 15: 149-57. PMID 12648670 DOI: 10.1016/S0955-0674(03)00012-7 |
0.772 |
|
| 2003 |
Prasanth KV, Sacco-Bubulya PA, Prasanth SG, Spector DL. Sequential entry of components of the gene expression machinery into daughter nuclei. Molecular Biology of the Cell. 14: 1043-57. PMID 12631722 DOI: 10.1091/Mbc.E02-10-0669 |
0.712 |
|
| 2003 |
Spector DL, Gasser SM. A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications. Embo Reports. 4: 18-23. PMID 12524514 DOI: 10.1038/Sj.Embor.Embor701 |
0.359 |
|
| 2002 |
Sacco-Bubulya P, Spector DL. Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing. The Journal of Cell Biology. 156: 425-36. PMID 11827980 DOI: 10.1083/Jcb.200107017 |
0.404 |
|
| 2002 |
Muratani M, Gerlich D, Janicki SM, Gebhard M, Eils R, Spector DL. Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus. Nature Cell Biology. 4: 106-10. PMID 11753375 DOI: 10.1038/Ncb740 |
0.744 |
|
| 2001 |
Heard E, Rougeulle C, Arnaud D, Avner P, Allis CD, Spector DL. Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell. 107: 727-38. PMID 11747809 DOI: 10.1016/S0092-8674(01)00598-0 |
0.326 |
|
| 2000 |
Tsukamoto T, Hashiguchi N, Janicki SM, Tumbar T, Belmont AS, Spector DL. Visualization of gene activity in living cells. Nature Cell Biology. 2: 871-8. PMID 11146650 DOI: 10.1038/35046510 |
0.438 |
|
| 2000 |
Mintz PJ, Spector DL. Compartmentalization of RNA processing factors within nuclear speckles. Journal of Structural Biology. 129: 241-51. PMID 10806074 DOI: 10.1006/Jsbi.2000.4213 |
0.47 |
|
| 2000 |
Raska I, Spector DL. An "Eclipse" over the cell nucleus at the turn of the century Journal of Structural Biology. 129: 101. PMID 10806062 DOI: 10.1006/Jsbi.2000.4257 |
0.301 |
|
| 2000 |
Eils R, Gerlich D, Tvaruskó W, Spector DL, Misteli T. Quantitative imaging of pre-mRNA splicing factors in living cells. Molecular Biology of the Cell. 11: 413-8. PMID 10679003 DOI: 10.1091/Mbc.11.2.413 |
0.622 |
|
| 2000 |
Lorenz P, Misteli T, Baker BF, Bennett CF, Spector DL. Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides. Nucleic Acids Research. 28: 582-92. PMID 10606658 DOI: 10.1093/Nar/28.2.582 |
0.521 |
|
| 1999 |
Mintz PJ, Patterson SD, Neuwald AF, Spahr CS, Spector DL. Purification and biochemical characterization of interchromatin granule clusters. The Embo Journal. 18: 4308-20. PMID 10428969 DOI: 10.1093/Emboj/18.15.4308 |
0.318 |
|
| 1999 |
Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Molecular Cell. 3: 697-705. PMID 10394358 DOI: 10.1016/S1097-2765(01)80002-2 |
0.634 |
|
| 1999 |
Tvaruskó W, Bentele M, Misteli T, Rudolf R, Kaether C, Spector DL, Gerdes HH, Eils R. Time-resolved analysis and visualization of dynamic processes in living cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 7950-5. PMID 10393928 DOI: 10.1073/Pnas.96.14.7950 |
0.512 |
|
| 1998 |
Misteli T, Cáceres JF, Clement JQ, Krainer AR, Wilkinson MF, Spector DL. Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. The Journal of Cell Biology. 143: 297-307. PMID 9786943 DOI: 10.1083/Jcb.143.2.297 |
0.64 |
|
| 1998 |
Huang S, Deerinck TJ, Ellisman MH, Spector DL. The perinucleolar compartment and transcription. The Journal of Cell Biology. 143: 35-47. PMID 9763419 DOI: 10.1083/Jcb.143.1.35 |
0.605 |
|
| 1998 |
Misteli T, Spector DL. The cellular organization of gene expression. Current Opinion in Cell Biology. 10: 323-31. PMID 9640532 DOI: 10.1016/S0955-0674(98)80007-0 |
0.646 |
|
| 1998 |
Lorenz P, Baker BF, Bennett CF, Spector DL. Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies. Molecular Biology of the Cell. 9: 1007-23. PMID 9571236 DOI: 10.1091/Mbc.9.5.1007 |
0.325 |
|
| 1997 |
Misteli T, Spector DL. Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends in Cell Biology. 7: 135-8. PMID 17708924 DOI: 10.1016/S0962-8924(96)20043-1 |
0.608 |
|
| 1997 |
Misteli T, Spector DL. Applications of the green fluorescent protein in cell biology and biotechnology. Nature Biotechnology. 15: 961-4. PMID 9335045 DOI: 10.1038/Nbt1097-961 |
0.543 |
|
| 1997 |
Cáceres JF, Misteli T, Screaton GR, Spector DL, Krainer AR. Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. The Journal of Cell Biology. 138: 225-38. PMID 9230067 DOI: 10.1083/Jcb.138.2.225 |
0.552 |
|
| 1997 |
Huang S, Mayeda A, Krainer AR, Spector DL. RCC1 and nuclear organization. Molecular Biology of the Cell. 8: 1143-57. PMID 9201722 DOI: 10.1091/Mbc.8.6.1143 |
0.622 |
|
| 1997 |
Misteli T, Cáceres JF, Spector DL. The dynamics of a pre-mRNA splicing factor in living cells. Nature. 387: 523-7. PMID 9168118 DOI: 10.1038/387523A0 |
0.635 |
|
| 1997 |
Huang S, Deerinck TJ, Ellisman MH, Spector DL. The dynamic organization of the perinucleolar compartment in the cell nucleus. The Journal of Cell Biology. 137: 965-74. PMID 9166399 DOI: 10.1083/Jcb.137.5.965 |
0.632 |
|
| 1996 |
Spector DL. Nuclear organization and gene expression. Experimental Cell Research. 229: 189-97. PMID 8986596 DOI: 10.1006/Excr.1996.0358 |
0.412 |
|
| 1996 |
Misteli T, Spector DL. Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors. Molecular Biology of the Cell. 7: 1559-72. PMID 8898362 DOI: 10.1091/Mbc.7.10.1559 |
0.61 |
|
| 1996 |
Huang S, Spector DL. Dynamic organization of pre-mRNA splicing factors. Journal of Cellular Biochemistry. 62: 191-7. PMID 8844399 DOI: 10.1002/(Sici)1097-4644(199608)62:2<191::Aid-Jcb7>3.0.Co;2-N |
0.616 |
|
| 1996 |
Henderson S, Allsopp R, Spector D, Wang SS, Harley C. In situ analysis of changes in telomere size during replicative aging and cell transformation. The Journal of Cell Biology. 134: 1-12. PMID 8698806 DOI: 10.1083/Jcb.134.1.1 |
0.301 |
|
| 1996 |
Huang S, Spector DL. Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcription. The Journal of Cell Biology. 133: 719-32. PMID 8666659 DOI: 10.1083/Jcb.133.4.719 |
0.628 |
|
| 1995 |
Tani T, Derby RJ, Hiraoka Y, Spector DL. Nucleolar accumulation of poly (A)+ RNA in heat-shocked yeast cells: implication of nucleolar involvement in mRNA transport. Molecular Biology of the Cell. 6: 1515-34. PMID 8589453 DOI: 10.1091/Mbc.6.11.1515 |
0.391 |
|
| 1994 |
O'Keefe RT, Mayeda A, Sadowski CL, Krainer AR, Spector DL. Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. The Journal of Cell Biology. 124: 249-60. PMID 8294510 DOI: 10.1083/Jcb.124.3.249 |
0.388 |
|
| 1994 |
Jiménez-García LF, Segura-Valdez ML, Ochs RL, Rothblum LI, Hannan R, Spector DL. Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis. Molecular Biology of the Cell. 5: 955-66. PMID 7841523 DOI: 10.1091/Mbc.5.9.955 |
0.379 |
|
| 1994 |
Deerinck TJ, Martone ME, Lev-Ram V, Green DP, Tsien RY, Spector DL, Huang S, Ellisman MH. Fluorescence photooxidation with eosin: a method for high resolution immunolocalization and in situ hybridization detection for light and electron microscopy. The Journal of Cell Biology. 126: 901-10. PMID 7519623 DOI: 10.1083/Jcb.126.4.901 |
0.46 |
|
| 1994 |
Huang S, Deerinck TJ, Ellisman MH, Spector DL. In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. The Journal of Cell Biology. 126: 877-99. PMID 7519622 DOI: 10.1083/Jcb.126.4.877 |
0.635 |
|
| 1993 |
Jiménez-García LF, Spector DL. In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism Cell. 73: 47-59. PMID 8462102 DOI: 10.1016/0092-8674(93)90159-N |
0.512 |
|
| 1993 |
Spector DL. Nuclear organization of pre-mRNA processing Current Opinion in Cell Biology. 5: 442-447. PMID 8352961 DOI: 10.1016/0955-0674(93)90009-F |
0.451 |
|
| 1993 |
Spector DL. Macromolecular domains within the cell nculeus Annual Review of Cell Biology. 9: 265-315. PMID 8280462 DOI: 10.1146/Annurev.Cb.09.110193.001405 |
0.452 |
|
| 1993 |
Spector DL, Landon S, O'Keefe RT. Organization of RNA polymerase II transcription and pre-mRNA splicing within the mammalian cell nucleus Biochemical Society Transactions. 21: 918-920. PMID 8132093 DOI: 10.1042/Bst0210918 |
0.405 |
|
| 1993 |
Spector DL, O'Keefe RT, Jimenez-Garcia LF. Dynamics of transcription and pre-mRNA splicing within the mammalian cell nucleus Cold Spring Harbor Symposia On Quantitative Biology. 58: 799-805. PMID 7956094 DOI: 10.1101/Sqb.1993.058.01.087 |
0.366 |
|
| 1992 |
Spector DL, Lark G, Huang S. Differences in snRNP localization between transformed and nontransformed cells Molecular Biology of the Cell. 3: 555-569. PMID 1535243 DOI: 10.1091/Mbc.3.5.555 |
0.516 |
|
| 1992 |
Huang S, Spector DL. U1 and U2 small nuclear RNAs are present in nuclear speckles Proceedings of the National Academy of Sciences of the United States of America. 89: 305-308. PMID 1530887 DOI: 10.1073/Pnas.89.1.305 |
0.603 |
|
| 1992 |
Romanelli MG, Mavromara-Nazos P, Spector D, Roizman B. Mutational analysis of the ICP4 binding sites in the 5' transcribed noncoding domains of the herpes simplex virus 1 UL 49.5 gamma 2 gene. Journal of Virology. 66: 4855-63. PMID 1321274 DOI: 10.1128/Jvi.66.8.4855-4863.1992 |
0.34 |
|
| 1992 |
Purves FC, Spector D, Roizman B. UL34, the target of the herpes simplex virus U(S)3 protein kinase, is a membrane protein which in its unphosphorylated state associates with novel phosphoproteins. Journal of Virology. 66: 4295-303. PMID 1318405 DOI: 10.1128/Jvi.66.7.4295-4303.1992 |
0.309 |
|
| 1992 |
Huang S, Spector DL. Will the real splicing sites please light up? Current Biology. 2: 188-190. DOI: 10.1016/0960-9822(92)90516-D |
0.455 |
|
| 1991 |
Spector DL, Fu XD, Maniatis T. Associations between distinct pre-mRNA splicing components and the cell nucleus Embo Journal. 10: 3467-3481. PMID 1833187 DOI: 10.1002/J.1460-2075.1991.Tb04911.X |
0.351 |
|
| 1991 |
Huang S, Spector DL. Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors Genes and Development. 5: 2288-2302. PMID 1748285 DOI: 10.1101/Gad.5.12A.2288 |
0.605 |
|
| 1991 |
Purves FC, Spector D, Roizman B. The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 gene. Journal of Virology. 65: 5757-64. PMID 1656069 DOI: 10.1128/Jvi.65.11.5757-5764.1991 |
0.301 |
|
| 1990 |
Potashkin JA, Derby RJ, Spector DL. Differential distribution of factors involved in pre-mRNA processing in the yeast cell nucleus. Molecular and Cellular Biology. 10: 3524-34. PMID 2192258 DOI: 10.1128/mcb.10.7.3524-3534.1990 |
0.419 |
|
| 1990 |
Spector DL. Higher order nuclear organization: Three-dimensional distribution of small nuclear ribonucleoprotein particles Proceedings of the National Academy of Sciences of the United States of America. 87: 147-151. PMID 2136950 DOI: 10.1073/Pnas.87.1.147 |
0.361 |
|
| 1989 |
Conway GC, Krainer AR, Spector DL, Roberts RJ. Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing. Molecular and Cellular Biology. 9: 5273-80. PMID 2531283 DOI: 10.1128/mcb.9.12.5273-5280.1989 |
0.346 |
|
| 1988 |
White E, Spector D, Welch W. Differential distribution of the adenovirus E1A proteins and colocalization of E1A with the 70-kilodalton cellular heat shock protein in infected cells Journal of Virology. 62: 4153-4166. PMID 2971821 DOI: 10.1128/Jvi.62.11.4153-4166.1988 |
0.307 |
|
| 1986 |
Smith HC, Ochs RL, Fernandez EA, Spector DL. Macromolecular domains containing nuclear protein p107 and U-snRNP protein p28: Further evidence for an in situ nuclear matrix Molecular and Cellular Biochemistry. 70: 151-168. PMID 2941679 DOI: 10.1007/Bf00229430 |
0.397 |
|
| 1986 |
Bennett CF, Spector DL, Yeoman LC. Nonhistone protein BA is a glutatione S-transferase localized to interchromatinic regions of the cell nucleus Journal of Cell Biology. 102: 600-609. PMID 2935545 DOI: 10.1083/Jcb.102.2.600 |
0.323 |
|
| 1985 |
Busch H, Ochs RL, Smith HC, Spector DL. Nuclear antigenic structures. Scandinavian Journal of Rheumatology. Supplement. 56: 10-21. PMID 3858986 |
0.451 |
|
| 1985 |
Smith HC, Spector DL, Woodcock CLF, Ochs RL, Bhorjee J. Alterations in chromatin conformation are accompanied by reorganization of nonchromatin domains that contain U-snRNP protein p28 and nuclear protein p107 Journal of Cell Biology. 101: 560-567. PMID 2991302 DOI: 10.1083/Jcb.101.2.560 |
0.31 |
|
| 1985 |
Reddy R, Henning D, Liu MH, Spector D, Busch H. Identification and characterization of a polyadenylated small RNA (s-poly A+ RNA) in dinoflagellates. Biochemical and Biophysical Research Communications. 127: 552-7. PMID 2579655 DOI: 10.1016/S0006-291X(85)80195-9 |
0.642 |
|
| 1984 |
Spector DL. Colocalization of U1 and U2 small nuclear RNPs by immunocytochemistry Biology of the Cell. 51: 109-112. PMID 6207877 DOI: 10.1111/J.1768-322X.1984.Tb00289.X |
0.352 |
|
| 1984 |
Spector DL, Ochs RL, Busch H. Silver staining, immunofluorescence, and immunoelectron microscopic localization of nucleolar phosphoproteins B23 and C23. Chromosoma. 90: 139-48. PMID 6206987 DOI: 10.1007/Bf00292451 |
0.582 |
|
| 1984 |
Liu M, Reddy R, Henning D, Spector D, Busch H. Primary and secondary structure of dinoflagellate U5 small nuclear RNA. Nucleic Acids Research. 12: 1529-1542. PMID 6199742 DOI: 10.1093/Nar/12.3.1529 |
0.637 |
|
| 1983 |
Spector DL, Schrier WH, Busch H. Immunoelectron microscopic localization of snRNPs. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 49: 1-10. PMID 6230127 DOI: 10.1111/J.1768-322X.1984.Tb00215.X |
0.537 |
|
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