Ronald C. Conaway - Publications

Affiliations: 
Stowers Institute for Medical Research, Kansas City, Missouri, Kansas City, MO, United States 

194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Herlihy AE, Boeing S, Weems JC, Walker J, Dirac-Svejstrup AB, Lehner MH, Conaway RC, Conaway JW, Svejstrup JQ. UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1. Dna Repair. 115: 103343. PMID 35633597 DOI: 10.1016/j.dnarep.2022.103343  0.748
2022 Suzuki H, Abe R, Shimada M, Hirose T, Hirose H, Noguchi K, Ike Y, Yasui N, Furugori K, Yamaguchi Y, Toyoda A, Suzuki Y, Yamamoto T, Saitoh N, Sato S, ... ... Conaway RC, et al. The 3' Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies' association with histone locus bodies. Nature Communications. 13: 2905. PMID 35614107 DOI: 10.1038/s41467-022-30632-w  0.757
2021 He Y, Sato S, Tomomori-Sato C, Chen S, Goode ZH, Conaway JW, Conaway RC. Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34544872 DOI: 10.1073/pnas.2108751118  0.79
2021 Ooi SK, Sato S, Tomomori-Sato C, Zhang Y, Wen Z, Banks CAS, Washburn MP, Unruh JR, Florens L, Conaway RC, Conaway JW. Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34465625 DOI: 10.1073/pnas.2107277118  0.697
2021 Weems JC, Slaughter BD, Unruh JR, Weaver KJ, Miller BD, Delventhal KM, Conaway JW, Conaway RC. A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription. The Journal of Biological Chemistry. 100862. PMID 34116057 DOI: 10.1016/j.jbc.2021.100862  0.767
2020 Yasukawa T, Tsutsui A, Tomomori-Sato C, Sato S, Saraf A, Washburn MP, Florens L, Terada T, Shimizu K, Conaway RC, Conaway JW, Aso T. NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. Cell Reports. 30: 3478-3491.e6. PMID 32160551 DOI: 10.1016/J.Celrep.2020.02.059  0.666
2020 Tufegdžić Vidaković A, Mitter R, Kelly GP, Neumann M, Harreman M, Rodríguez-Martínez M, Herlihy A, Weems JC, Boeing S, Encheva V, Gaul L, Milligan L, Tollervey D, Conaway RC, Conaway JW, et al. Regulation of the RNAPII Pool Is Integral to the DNA Damage Response. Cell. PMID 32142654 DOI: 10.1016/J.Cell.2020.02.009  0.728
2020 Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, ... ... Conaway RC, et al. The role of Mediator and Little Elongation Complex in transcription termination. Nature Communications. 11: 1063. PMID 32102997 DOI: 10.1038/S41467-020-14849-1  0.847
2020 SATO S, Tomomori-Sato C, Ranjan A, Conaway RC, Conaway JW. Structure and functions of the Mediator complex: A key regulator of RNA polymerase II transcription The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09467  0.792
2020 Ranjan A, Chen S, Goode Z, Sato S, Sato C, Takahashi H, Conaway R, Conaway JW. Roles of Mediator subunit MED26 in Regulation of Post‐initiation Events in RNA Pol II Transcription The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09368  0.783
2020 He Y, Tomomori-Sato C, Sato S, Conaway JW, Conaway RC. Mechanisms of Transcriptional Regulation by an ER Stress‐Responsive Enhancer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07580  0.716
2020 Ooi S, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW. ACTIVATION OF ALC1 (CHD1L) NUCLEOSOME REMODELING BY PARP‐1‐DEPENDENT POLY(ADP‐RIBOSYL)ATION The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06254  0.681
2019 Conaway RC, Conaway JW. The hunt for RNA polymerase II elongation factors: a historical perspective. Nature Structural & Molecular Biology. PMID 31439940 DOI: 10.1038/S41594-019-0283-1  0.778
2019 Tettey TT, Gao X, Shao W, Li H, Story BA, Chitsazan AD, Glaser RL, Goode ZH, Seidel CW, Conaway RC, Zeitlinger J, Blanchette M, Conaway JW. A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing. Cell Reports. 27: 3770-3779.e7. PMID 31242411 DOI: 10.1016/J.Celrep.2019.05.099  0.783
2019 Noe Gonzalez M, Conaway JW, Conaway RC. Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events. Journal of Visualized Experiments : Jove. PMID 31132066 DOI: 10.3791/59497  0.79
2019 Wang LY, He YX, Li M, Ding J, Sui Y, Conaway JW, Conaway RC, Wang F, Jin J, Cai Y. DNA-dependent protein kinase catalytic subunit (DNA-PKcs) contributes to incorporation of histone variant H2A.Z into nucleosomes. Protein & Cell. PMID 31111444 DOI: 10.1007/S13238-019-0632-1  0.695
2019 Weems JC, Unruh JR, Slaughter BD, Conaway RC, Conaway JW. Imaging-based assays for investigating functions of the RNA polymerase II elongation factor Elongin and the Elongin ubiquitin ligase. Methods (San Diego, Calif.). PMID 30794906 DOI: 10.1016/J.Ymeth.2019.02.015  0.782
2018 Noe Gonzalez M, Conaway RC, Conaway JW. Frozen in Transcription: Cryo-EM Structures of Pol II Transcribing through a Nucleosome. Molecular Cell. 72: 802-804. PMID 30526870 DOI: 10.1016/J.Molcel.2018.11.027  0.733
2018 Noe Gonzalez M, Sato S, Tomomori-Sato C, Conaway JW, Conaway RC. CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts. Nature Communications. 9: 3392. PMID 30139934 DOI: 10.1038/S41467-018-05923-W  0.788
2018 Gopalan S, Gibbon DM, Banks CAS, Zhang Y, Florens LA, Washburn MP, Dabas P, Sharma N, Seidel CW, Conaway RC, Conaway JW. Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex. Nucleic Acids Research. PMID 30102332 DOI: 10.1093/Nar/Gky713  0.8
2018 Conaway RC. Metabolic Regulation of Transcription and Chromatin. Annual Review of Biochemistry. 87: 23-25. PMID 29925254 DOI: 10.1146/Annurev-Biochem-062917-012600  0.479
2017 Wu DL, Zhao LH, Feng ZT, Yu C, Ding J, Wang LY, Wang F, Liu D, Zhu HH, Xing FY, Conaway JW, Conaway RC, Cai Y, Jin JJ. O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the non-specific lethal protein NSL3. The Journal of Biological Chemistry. PMID 28450392 DOI: 10.1074/Jbc.M117.781401  0.693
2017 Weems JC, Slaughter BD, Unruh JR, Boeing S, Hall SM, McLaird MB, Yasukawa T, Aso T, Svejstrup JQ, Conaway JW, Conaway RC. Cockayne Syndrome B Protein Regulates Recruitment of the Elongin A Ubiquitin Ligase to Sites of DNA Damage. The Journal of Biological Chemistry. PMID 28292928 DOI: 10.1074/Jbc.C117.777946  0.74
2017 Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias FJ. Mediator structure and rearrangements required for holoenzyme formation. Nature. PMID 28241144 DOI: 10.1038/Nature21393  0.778
2016 Sato S, Tomomori-Sato C, Tsai KL, Yu X, Sardiu M, Saraf A, Washburn MP, Florens L, Asturias FJ, Conaway RC, Conaway JW. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme. The Journal of Biological Chemistry. PMID 27821593 DOI: 10.1074/Jbc.M116.756098  0.761
2016 Boeing S, Williamson L, Encheva V, Gori I, Saunders RE, Instrell R, Aygün O, Rodriguez-Martinez M, Weems JC, Kelly GP, Conaway JW, Conaway RC, Stewart A, Howell M, Snijders AP, et al. Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Reports. PMID 27184836 DOI: 10.1016/J.Celrep.2016.04.047  0.692
2015 Masuda Y, Takahashi H, Sato S, Tomomori-Sato C, Saraf A, Washburn MP, Florens L, Conaway RC, Conaway JW, Hatakeyama S. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nature Communications. 6: 7299. PMID 26095369 DOI: 10.1038/Ncomms8299  0.722
2015 Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells. Plos One. 10: e0126328. PMID 25902070 DOI: 10.1371/Journal.Pone.0126328  0.652
2015 Weems JC, Slaughter BD, Unruh JR, Hall SM, McLaird MB, Gilmore JM, Washburn MP, Florens L, Yasukawa T, Aso T, Conaway JW, Conaway RC. Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses. The Journal of Biological Chemistry. 290: 15030-41. PMID 25878247 DOI: 10.1074/Jbc.M114.632794  0.782
2015 Conaway RC, Conaway JW. Orchestrating transcription with the Pol II CTD. Nature Reviews. Molecular Cell Biology. 16: 128. PMID 25693123 DOI: 10.1038/Nrm3956  0.783
2015 Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, et al. MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex. Nature Communications. 6: 5941. PMID 25575120 DOI: 10.1038/Ncomms6941  0.756
2015 Sardiu ME, Gilmore JM, Groppe BD, Herman D, Ramisetty SR, Cai Y, Jin J, Conaway RC, Conaway JW, Florens L, Washburn MP. Conserved abundance and topological features in chromatin-remodeling protein interaction networks. Embo Reports. 16: 116-26. PMID 25427557 DOI: 10.15252/Embr.201439403  0.686
2015 Conaway RC, Conaway JW. Orchestrating transcription with the pol II CTD Nature Reviews Molecular Cell Biology. 16: 128. DOI: 10.1038/nrm3956  0.74
2014 Tsai KL, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Asturias FJ. Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex. Cell. 158: 463. PMID 28915369 DOI: 10.1016/j.cell.2014.06.036  0.734
2014 Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, Chong J, Conaway RC, Conaway JW, Ranish JA, Kadonaga JT, Russell P, Wang D. Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. Proceedings of the National Academy of Sciences of the United States of America. 111: 18566-71. PMID 25512493 DOI: 10.1073/Pnas.1420227112  0.732
2014 Chen L, Ooi SK, Conaway JW, Conaway RC. Biochemical assays for analyzing activities of ATP-dependent chromatin remodeling enzymes Journal of Visualized Experiments. PMID 25407555 DOI: 10.3791/51721  0.736
2014 Chen L, Ooi SK, Conaway RC, Conaway JW. Generation and purification of human INO80 chromatin remodeling complexes and subcomplexes Journal of Visualized Experiments. PMID 25407439 DOI: 10.3791/51720  0.74
2014 Tsai KL, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Asturias FJ. Subunit architecture and functional modular rearrangements of the transcriptional mediator complex. Cell. 157: 1430-44. PMID 24882805 DOI: 10.1016/J.Cell.2014.05.015  0.794
2014 Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. Plos One. 9: e87003. PMID 24466310 DOI: 10.1371/Journal.Pone.0087003  0.708
2013 Chen L, Conaway RC, Conaway JW. Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 20497-502. PMID 24297934 DOI: 10.1073/Pnas.1317092110  0.755
2013 Zhao X, Su J, Wang F, Liu D, Ding J, Yang Y, Conaway JW, Conaway RC, Cao L, Wu D, Wu M, Cai Y, Jin J. Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes. Plos Genetics. 9: e1003940. PMID 24244196 DOI: 10.1371/Journal.Pgen.1003940  0.739
2013 Sela D, Conkright JJ, Chen L, Gilmore J, Washburn MP, Florens L, Conaway RC, Conaway JW. Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α. The Journal of Biological Chemistry. 288: 26179-87. PMID 23864652 DOI: 10.1074/Jbc.M113.496968  0.732
2013 Kawauchi J, Inoue M, Fukuda M, Uchida Y, Yasukawa T, Conaway RC, Conaway JW, Aso T, Kitajima S. Transcriptional properties of mammalian elongin A and its role in stress response. The Journal of Biological Chemistry. 288: 24302-15. PMID 23828199 DOI: 10.1074/Jbc.M113.496703  0.777
2013 Tsai KL, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Asturias FJ. A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction. Nature Structural & Molecular Biology. 20: 611-9. PMID 23563140 DOI: 10.1038/Nsmb.2549  0.786
2013 Tomomori-Sato C, Sato S, Conaway RC, Conaway JW. Immunoaffinity purification of protein complexes from mammalian cells Methods in Molecular Biology. 977: 273-287. PMID 23436370 DOI: 10.1007/978-1-62703-284-1_22  0.693
2013 Conaway RC, Conaway JW. The Mediator complex and transcription elongation Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. 1829: 69-75. PMID 22983086 DOI: 10.1016/J.Bbagrm.2012.08.017  0.786
2013 Chen L, Conaway RC, Conaway JW. Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatinremodeling complex Proceedings of the National Academy of Sciences of the United States of America. 110: 20497-20502. DOI: 10.1073/pnas.1317092110  0.735
2012 Gottschalk AJ, Trivedi RD, Conaway JW, Conaway RC. Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate. The Journal of Biological Chemistry. 287: 43527-32. PMID 23132853 DOI: 10.1074/Jbc.M112.401141  0.705
2012 Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, Muraoka T, Inoue M, Tsuda M, Kitajima S, Conaway RC, Conaway JW, Trainor PA, Aso T. Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation. Cell Reports. 2: 1129-36. PMID 23122963 DOI: 10.1016/J.Celrep.2012.09.031  0.743
2012 Costessi A, Mahrour N, Sharma V, Stunnenberg R, Stoel MA, Tijchon E, Conaway JW, Conaway RC, Stunnenberg HG. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. Plos One. 7: e42822. PMID 22912744 DOI: 10.1371/Journal.Pone.0042822  0.713
2012 Sela D, Chen L, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes. The Journal of Biological Chemistry. 287: 23035-45. PMID 22577136 DOI: 10.1074/Jbc.M112.369504  0.764
2012 Gottschalk AJ, Trivedi RD, Conaway JW, Conaway RC. Abstract LB-373: Parp1 dependent regulation of chromatin remodeling by the ALC1 (Amplified in Liver Cancer) oncogene Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-373  0.741
2011 Costessi A, Mahrour N, Tijchon E, Stunnenberg R, Stoel MA, Jansen PW, Sela D, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC, Stunnenberg HG. The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. The Embo Journal. 30: 3786-98. PMID 21822215 DOI: 10.1038/Emboj.2011.262  0.748
2011 Conaway RC, Conaway JW. Origins and activity of the Mediator complex Seminars in Cell and Developmental Biology. 22: 729-734. PMID 21821140 DOI: 10.1016/J.Semcdb.2011.07.021  0.803
2011 Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, ... Conaway RC, et al. Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell. 146: 92-104. PMID 21729782 DOI: 10.1016/J.Cell.2011.06.005  0.802
2011 Conaway RC, Conaway JW. Function and regulation of the Mediator complex Current Opinion in Genetics and Development. 21: 225-230. PMID 21330129 DOI: 10.1016/J.Gde.2011.01.013  0.795
2011 Chen L, Cai Y, Jin J, Florens L, Swanson SK, Washburn MP, Conaway JW, Conaway RC. Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. The Journal of Biological Chemistry. 286: 11283-9. PMID 21303910 DOI: 10.1074/Jbc.M111.222505  0.756
2011 Capotosti F, Guernier S, Lammers F, Waridel P, Cai Y, Jin J, Conaway JW, Conaway RC, Herr W. O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell. 144: 376-88. PMID 21295698 DOI: 10.1016/J.Cell.2010.12.030  0.691
2010 Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular Cell. 37: 429-37. PMID 20159561 DOI: 10.1016/J.Molcel.2010.01.026  0.762
2010 Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, Florens L, Washburn MP, Conaway JW, Conaway RC. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. The Journal of Biological Chemistry. 285: 4268-72. PMID 20018852 DOI: 10.1074/Jbc.C109.087981  0.72
2009 Harreman M, Taschner M, Sigurdsson S, Anindya R, Reid J, Somesh B, Kong SE, Banks CAS, Conaway RC, Conaway JW, Svejstrup JQ. Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation Proceedings of the National Academy of Sciences of the United States of America. 106: 20705-20710. PMID 19920177 DOI: 10.1073/Pnas.0907052106  0.757
2009 Takahashi H, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC. Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID. The Journal of Biological Chemistry. 284: 32405-12. PMID 19805548 DOI: 10.1074/Jbc.M109.017954  0.752
2009 Gottschalk AJ, Timinszky G, Kong SE, Jin J, Cai Y, Swanson SK, Washburn MP, Florens L, Ladurner AG, Conaway JW, Conaway RC. Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler Proceedings of the National Academy of Sciences of the United States of America. 106: 13770-13774. PMID 19666485 DOI: 10.1073/Pnas.0906920106  0.729
2009 Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ. Direct inhibition of RNA polymerase II transcription by RECQL5. The Journal of Biological Chemistry. 284: 23197-203. PMID 19570979 DOI: 10.1074/Jbc.M109.015750  0.784
2009 Conaway RC, Conaway JW. Mediator Comes Out from the Shadows Structure. 17: 485-486. PMID 19368880 DOI: 10.1016/J.Str.2009.03.003  0.679
2009 Conaway RC, Conaway JW. The INO80 chromatin remodeling complex in transcription, replication and repair Trends in Biochemical Sciences. 34: 71-77. PMID 19062292 DOI: 10.1016/J.Tibs.2008.10.010  0.752
2009 Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Boyer TG. MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. The Journal of Biological Chemistry. 284: 2648-56. PMID 19049968 DOI: 10.1074/Jbc.M806514200  0.703
2008 Yasukawa T, Kamura T, Kitajima S, Conaway RC, Conaway JW, Aso T. Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1 Embo Journal. 27: 3256-3266. PMID 19037258 DOI: 10.1038/Emboj.2008.249  0.777
2008 Yao T, Song L, Jin J, Cai Y, Takahashi H, Swanson SK, Washburn MP, Florens L, Conaway RC, Cohen RE, Conaway JW. Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Molecular Cell. 31: 909-17. PMID 18922472 DOI: 10.1016/J.Molcel.2008.08.027  0.763
2008 Gottschalk AJ, Conaway RC, Conaway JW. New clues to actin function in chromatin regulation Nature Structural and Molecular Biology. 15: 432-433. PMID 18461045 DOI: 10.1038/Nsmb0508-432  0.735
2008 Sardiu ME, Cai Y, Jin J, Swanson SK, Conaway RC, Conaway JW, Florens L, Washburn MP. Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics. Proceedings of the National Academy of Sciences of the United States of America. 105: 1454-9. PMID 18218781 DOI: 10.1073/Pnas.0706983105  0.695
2008 Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. The Journal of Biological Chemistry. 283: 8005-13. PMID 18187417 DOI: 10.1074/Jbc.M706987200  0.732
2008 Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP, Kokkinaki M, Conaway RC, Conaway JW, Moschonas NK. Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. The Journal of Biological Chemistry. 283: 3846-53. PMID 18077452 DOI: 10.1074/Jbc.M706974200  0.672
2007 Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW. YY1 functions with INO80 to activate transcription. Nature Structural & Molecular Biology. 14: 872-4. PMID 17721549 DOI: 10.1038/Nsmb1276  0.752
2007 Banks CA, Kong SE, Spahr H, Florens L, Martin-Brown S, Washburn MP, Conaway JW, Mushegian A, Conaway RC. Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. The Journal of Biological Chemistry. 282: 5761-9. PMID 17150956 DOI: 10.1074/Jbc.M610393200  0.792
2006 Svejstrup JQ, Conaway RC, Conaway JW. RNA Polymerase II: A "Nobel" Enzyme Demystified Molecular Cell. 24: 637-642. PMID 17157247 DOI: 10.1016/J.Molcel.2006.11.016  0.75
2006 Paoletti AC, Parmely TJ, Tomomori-Sato C, Sato S, Zhu D, Conaway RC, Conaway JW, Florens L, Washburn MP. Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proceedings of the National Academy of Sciences of the United States of America. 103: 18928-33. PMID 17138671 DOI: 10.1073/Pnas.0606379103  0.788
2006 Charlet-Berguerand N, Feuerhahn S, Kong SE, Ziserman H, Conaway JW, Conaway R, Egly JM. RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors Embo Journal. 25: 5481-5491. PMID 17110932 DOI: 10.1038/Sj.Emboj.7601403  0.743
2006 Cai Y, Jin J, Gottschalk AJ, Yao T, Conaway JW, Conaway RC. Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes Methods. 40: 312-317. PMID 17101442 DOI: 10.1016/J.Ymeth.2006.06.023  0.727
2006 Yao T, Song L, Xu W, DeMartino GN, Florens L, Swanson SK, Washburn MP, Conaway RC, Conaway JW, Cohen RE. Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nature Cell Biology. 8: 994-1002. PMID 16906146 DOI: 10.1038/Ncb1460  0.731
2006 Ruhl DD, Jin J, Cai Y, Swanson S, Florens L, Washburn MP, Conaway RC, Conaway JW, Chrivia JC. Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry. 45: 5671-7. PMID 16634648 DOI: 10.1021/Bi060043D  0.734
2005 Jin J, Cai Y, Li B, Conaway RC, Workman JL, Conaway JW, Kusch T. In and out: histone variant exchange in chromatin. Trends in Biochemical Sciences. 30: 680-7. PMID 16257529 DOI: 10.1016/J.Tibs.2005.10.003  0.692
2005 Jin J, Cai Y, Yao T, Gottschalk AJ, Florens L, Swanson SK, Gutiérrez JL, Coleman MK, Workman JL, Mushegian A, Washburn MP, Conaway RC, Conaway JW. A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. The Journal of Biological Chemistry. 280: 41207-12. PMID 16230350 DOI: 10.1074/Jbc.M509128200  0.743
2005 Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC. ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 102: 10094-8. PMID 16006523 DOI: 10.1073/Pnas.0503017102  0.792
2005 Conaway RC, Sato S, Tomomori-Sato C, Yao T, Conaway JW. The mammalian Mediator complex and its role in transcriptional regulation Trends in Biochemical Sciences. 30: 250-255. PMID 15896743 DOI: 10.1016/J.Tibs.2005.03.002  0.795
2005 Conaway JW, Florens L, Sato S, Tomomori-Sato C, Parmely TJ, Yao T, Swanson SK, Banks CA, Washburn MP, Conaway RC. The mammalian Mediator complex. Febs Letters. 579: 904-8. PMID 15680972 DOI: 10.1016/J.Febslet.2004.11.031  0.803
2005 Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW. The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. The Journal of Biological Chemistry. 280: 13665-70. PMID 15647280 DOI: 10.1074/Jbc.M500001200  0.759
2005 Gerber M, Tenney K, Conaway JW, Conaway RC, Eissenberg JC, Shilatifard A. Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of Biological Chemistry. 280: 4017-20. PMID 15611125 DOI: 10.1074/Jbc.C400487200  0.746
2005 Heuzé ML, Guibal FC, Banks CA, Conaway JW, Conaway RC, Cayre YE, Benecke A, Lutz PG. ASB2 is an elongin BC-interacting protein that can assemble with cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex Journal of Biological Chemistry. 280: 5468-5474. PMID 15590664 DOI: 10.1074/Jbc.M413040200  0.731
2004 Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases Genes and Development. 18: 3055-3065. PMID 15601820 DOI: 10.1101/Gad.1252404  0.746
2004 Gerber M, Eissenberg JC, Kong S, Tenney K, Conaway JW, Conaway RC, Shilatifard A. In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Molecular and Cellular Biology. 24: 9911-9. PMID 15509793 DOI: 10.1128/Mcb.24.22.9911-9919.2004  0.802
2004 Blanchette P, Cheng CY, Yan Q, Ketner G, Ornelles DA, Dobner T, Conaway RC, Conaway JW, Branton PE. Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Molecular and Cellular Biology. 24: 9619-29. PMID 15485928 DOI: 10.1128/Mcb.24.21.9619-9629.2004  0.732
2004 Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW. Identification of Elongin C and Skp1 sequences that determine Cullin selection. The Journal of Biological Chemistry. 279: 43019-26. PMID 15280393 DOI: 10.1074/Jbc.M408018200  0.712
2004 Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, Swanson SK, Banks CA, Jin J, Cai Y, Washburn MP, Conaway JW, Conaway RC. A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Molecular Cell. 14: 685-91. PMID 15175163 DOI: 10.1016/J.Molcel.2004.05.006  0.781
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/J.Molcel.2004.05.011  0.81
2004 Tomomori-Sato C, Sato S, Parmely TJ, Banks CA, Sorokina I, Florens L, Zybailov B, Washburn MP, Brower CS, Conaway RC, Conaway JW. A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. The Journal of Biological Chemistry. 279: 5846-51. PMID 14638676 DOI: 10.1074/Jbc.M312523200  0.757
2004 Conaway C, Conaway R, Proudfoot N, Reinberg D, Timmers H. RNA Polymerase II Transcription Reactome - a Curated Knowledgebase of Biological Pathways. 8. DOI: 10.3180/React_1366.1  0.513
2003 Kong SE, Shilatifard A, Conaway RC, Conaway JW. Preparation and Assay of RNA Polymerase II Elongation Factors Elongin and ELL Methods in Enzymology. 371: 276-283. PMID 14712707 DOI: 10.1016/S0076-6879(03)71020-9  0.778
2003 Dvir A, Conaway JW, Conaway RC. Assays for Investigating the Mechanism of Promoter Escape by RNA Polymerase II Methods in Enzymology. 370: 733-740. PMID 14712687 DOI: 10.1016/S0076-6879(03)70059-7  0.804
2003 Sato S, Tomomori-Sato C, Banks CA, Parmely TJ, Sorokina I, Brower CS, Conaway RC, Conaway JW. A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. The Journal of Biological Chemistry. 278: 49671-4. PMID 14576168 DOI: 10.1074/Jbc.C300444200  0.773
2003 Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I, Parmely TJ, Conaway RC, Conaway JW. Identification of New Subunits of the Multiprotein Mammalian TRRAP/TIP60-containing Histone Acetyltransferase Complex Journal of Biological Chemistry. 278: 42733-42736. PMID 12963728 DOI: 10.1074/Jbc.C300389200  0.728
2003 Conaway RC, Kong SE, Conaway JW. TFIIS and GreB: Two like-minded transcription elongation factors with sticky fingers Cell. 114: 272-274. PMID 12914690 DOI: 10.1016/S0092-8674(03)00607-X  0.726
2003 Shilatifard A, Conaway RC, Conaway JW. The RNA polymerase II elongation complex. Annual Review of Biochemistry. 72: 693-715. PMID 12676794 DOI: 10.1146/Annurev.Biochem.72.121801.161551  0.786
2003 Kuznetsova AV, Meller J, Schnell PO, Nash JA, Ignacak ML, Sanchez Y, Conaway JW, Conaway RC, Czyzyk-Krzeska MF. von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 100: 2706-11. PMID 12604794 DOI: 10.1073/Pnas.0436037100  0.774
2003 Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, Jin J, Cai Y, Lane WS, Brower CS, Conaway RC, Conaway JW. Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. The Journal of Biological Chemistry. 278: 15123-7. PMID 12584197 DOI: 10.1074/Jbc.C300054200  0.749
2003 Maynard MA, Qi H, Chung J, Lee EH, Kondo Y, Hara S, Conaway RC, Conaway JW, Ohh M. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. The Journal of Biological Chemistry. 278: 11032-40. PMID 12538644 DOI: 10.1074/Jbc.M208681200  0.696
2002 Conaway RC, Conaway JW. The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription Advances in Cancer Research. 85: 1-12. PMID 12374282 DOI: 10.1016/S0065-230X(02)85001-1  0.726
2002 Ivan M, Haberberger T, Gervasi DC, Michelson KS, Günzler V, Kondo K, Yang H, Sorokina I, Conaway RC, Conaway JW, Kaelin WG. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proceedings of the National Academy of Sciences of the United States of America. 99: 13459-64. PMID 12351678 DOI: 10.1073/Pnas.192342099  0.694
2002 Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 99: 10353-8. PMID 12149480 DOI: 10.1073/Pnas.162424199  0.791
2002 Kamura T, Brower CS, Conaway RC, Conaway JW. A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase Journal of Biological Chemistry. 277: 30388-30393. PMID 12048197 DOI: 10.1074/Jbc.M203344200  0.734
2002 Conaway RC, Brower CS, Conaway JW. Emerging roles of ubiquitin in transcription regulation Science. 296: 1254-1258. PMID 12016299 DOI: 10.1126/Science.1067466  0.787
2002 Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex Nature. 416: 703-709. PMID 11961546 DOI: 10.1038/416703A  0.693
2002 Kamura T, Conaway JW, Conaway RC. Roles of SCF and VHL ubiquitin ligases in regulation of cell growth Progress in Molecular and Subcellular Biology. 29: 1-15. PMID 11908068 DOI: 10.1007/978-3-642-56373-7_1  0.707
2001 Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D, Kaelin WG, Conaway RC, Conaway JW, Branton PE. Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex Genes and Development. 15: 3104-3117. PMID 11731475 DOI: 10.1101/Gad.926401  0.725
2001 Kamura T, Burian D, Yan Q, Schmidt SL, Lane WS, Querido E, Branton PE, Shilatifard A, Conaway RC, Conaway JW. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. The Journal of Biological Chemistry. 276: 29748-53. PMID 11384984 DOI: 10.1074/Jbc.M103093200  0.737
2001 Spangler L, Wang X, Conaway JW, Conaway RC, Dvir A. TFIIH action in transcription initiation and promoter escape requires distinct regions of downstream promoter DNA Proceedings of the National Academy of Sciences of the United States of America. 98: 5544-5549. PMID 11331764 DOI: 10.1073/Pnas.101004498  0.78
2001 Kamura T, Burian D, Khalili H, Schmidt SL, Sato S, Liu WJ, Conrad MN, Conaway RC, Conaway JW, Shilatifard A. Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose. The Journal of Biological Chemistry. 276: 16528-33. PMID 11278625 DOI: 10.1074/Jbc.M010142200  0.731
2001 Elmendorf BJ, Shilatifard A, Yan Q, Conaway JW, Conaway RC. Transcription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation Intermediates Journal of Biological Chemistry. 276: 23109-23114. PMID 11259417 DOI: 10.1074/Jbc.M101445200  0.791
2001 Dvir A, Conaway JW, Conaway RC. Mechanism of transcription initiation and promoter escape by RNA polymerase II Current Opinion in Genetics and Development. 11: 209-214. PMID 11250146 DOI: 10.1016/S0959-437X(00)00181-7  0.776
2001 Liu J, Akoulitchev S, Weber A, Ge H, Chuikov S, Libutti D, Wang XW, Conaway JW, Harris CC, Conaway RC, Reinberg D, Levens D. Defective interplay of activators and repressors with TFIIH in xeroderma pigmentosum Cell. 104: 353-363. PMID 11239393 DOI: 10.1016/S0092-8674(01)00223-9  0.73
2000 Kamura T, Sato S, Iwai K, Czyzyk-Krzeska M, Conaway RC, Conaway JW. Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex Proceedings of the National Academy of Sciences of the United States of America. 97: 10430-10435. PMID 10973499 DOI: 10.1073/Pnas.190332597  0.734
2000 Conaway JW, Shilatifard A, Dvir A, Conaway RC. Control of elongation by RNA polymerase II Trends in Biochemical Sciences. 25: 375-380. PMID 10916156 DOI: 10.1016/S0968-0004(00)01615-7  0.795
2000 Conaway JW, Conaway RC. Light at the end of the channel Science. 288: 632-633. PMID 10799002 DOI: 10.1126/Science.288.5466.632  0.7
2000 Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS. Identification of a transcription factor IIIA-interacting protein Nucleic Acids Research. 28: 1986-1993. PMID 10756201 DOI: 10.1093/Nar/28.9.1986  0.762
2000 Koth CM, Botuyan MV, Moreland RJ, Jansma DB, Conaway JW, Conaway RC, Chazin WJ, Friesen JD, Arrowsmith CH, Edwards AM. Elongin from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 275: 11174-80. PMID 10753924 DOI: 10.1074/Jbc.275.15.11174  0.728
1999 Conaway JW, Conaway RC. Transcription elongation and human disease Annual Review of Biochemistry. 68: 301-319. PMID 10872452 DOI: 10.1146/Annurev.Biochem.68.1.301  0.78
1999 Ohh M, Takagi Y, Aso T, Stebbins CE, Pavletich NP, Zbar B, Conaway RC, Conaway JW, Kaelin WG. Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein Journal of Clinical Investigation. 104: 1583-1591. PMID 10587522 DOI: 10.1172/Jci8161  0.683
1999 Yan Q, Moreland RJ, Conaway JW, Conaway RC. Dual roles for transcription factor IIF in promoter escape by RNA polymerase II Journal of Biological Chemistry. 274: 35668-35675. PMID 10585446 DOI: 10.1074/Jbc.274.50.35668  0.798
1999 Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 Genes and Development. 13: 2928-2933. PMID 10579999 DOI: 10.1101/Gad.13.22.2928  0.708
1999 Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. Proceedings of the National Academy of Sciences of the United States of America. 96: 12436-41. PMID 10535940 DOI: 10.1073/Pnas.96.22.12436  0.722
1999 Kroll SL, Paulding WR, Schnell PO, Barton MC, Conaway JW, Conaway RC, Czyzyk-Krzeska MF. von Hippel-Lindau protein induces hypoxia-regulated arrest of tyrosine hydroxylase transcript elongation in pheochromocytoma cells Journal of Biological Chemistry. 274: 30109-30114. PMID 10514498 DOI: 10.1074/Jbc.274.42.30109  0.73
1999 Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ. Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C Proceedings of the National Academy of Sciences of the United States of America. 96: 9033-9038. PMID 10430890 DOI: 10.1073/Pnas.96.16.9033  0.71
1999 Moreland RJ, Tirode F, Yan Q, Conaway JW, Egly JM, Conaway RC. A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II Journal of Biological Chemistry. 274: 22127-22130. PMID 10428772 DOI: 10.1074/Jbc.274.32.22127  0.792
1999 Reines D, Conaway RC, Conaway JW. Mechanism and regulation of transcriptional elongation by RNA polymerase II Current Opinion in Cell Biology. 11: 342-346. PMID 10395562 DOI: 10.1016/S0955-0674(99)80047-7  0.786
1999 Brower CS, Shilatifard A, Mather T, Kamura T, Takagi Y, Haque D, Treharne A, Foundling SI, Conaway JW, Conaway RC. The Elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C Journal of Biological Chemistry. 274: 13629-13636. PMID 10224134 DOI: 10.1074/Jbc.274.19.13629  0.727
1999 Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW. Reconstitution of G1 cyclin ubiquitination with complexes containing SCF(Grr1) and Rbx1 Science. 284: 662-665. PMID 10213692 DOI: 10.1126/Science.284.5414.662  0.726
1999 Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase Science. 284: 657-661. PMID 10213691 DOI: 10.1126/Science.284.5414.657  0.728
1998 Conaway JW, Dvir A, Moreland RJ, Yan Q, Elmendorf BJ, Tan S, Conaway RC. Mechanism of promoter escape by RNA polymerase II Cold Spring Harbor Symposia On Quantitative Biology. 63: 357-364. PMID 10384300 DOI: 10.1101/Sqb.1998.63.357  0.735
1998 Kamura T, Sato S, Haque D, Liu L, Kaelin WG, Conaway RC, Conaway JW. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families Genes and Development. 12: 3872-3881. PMID 9869640 DOI: 10.1101/Gad.12.24.3872  0.77
1998 Moreland RJ, Hanas JS, Conaway JW, Conaway RC. Mechanism of action of RNA polymerase II elongation factor elongin. Maximal stimulation of elongation requires conversion of the early elongation complex to an elongin-activable form Journal of Biological Chemistry. 273: 26610-26617. PMID 9756900 DOI: 10.1074/Jbc.273.41.26610  0.785
1998 Jiang YW, Veschambre P, Erdjument-Bromage H, Tempst P, Conaway JW, Conaway RC, Kornberg RD. Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proceedings of the National Academy of Sciences of the United States of America. 95: 8538-43. PMID 9671713 DOI: 10.1073/Pnas.95.15.8538  0.774
1998 Conaway JW, Kamura T, Conaway RC. The Elongin BC complex and the von Hippel-Lindau tumor suppressor protein Biochimica Et Biophysica Acta - Reviews On Cancer. 1377. PMID 9606976 DOI: 10.1016/S0304-419X(97)00035-8  0.686
1998 Trigon S, Serizawa H, Conaway JW, Conaway RC, Jackson SP, Morange M. Characterization of the residues phosphorylated in vitro by different C- terminal domain kinases Journal of Biological Chemistry. 273: 6769-6775. PMID 9506978 DOI: 10.1074/Jbc.273.12.6769  0.664
1998 Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG. Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2 Molecular and Cellular Biology. 18: 732-741. PMID 9447969 DOI: 10.1128/Mcb.18.2.732  0.729
1997 Dvir A, Tan S, Conaway JW, Conaway RC. Promoter escape by RNA polymerase II : Formation of escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter Journal of Biological Chemistry. 272: 28175-28178. PMID 9353262 DOI: 10.1074/Jbc.272.45.28175  0.792
1997 Takagi Y, Pause A, Conaway RC, Conaway JW. Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein. The Journal of Biological Chemistry. 272: 27444-9. PMID 9341197 DOI: 10.1074/Jbc.272.43.27444  0.728
1997 Shilatifard A, Haque D, Conaway RC, Conaway JW. Structure and function of RNA polymerase II elongation factor ELL: Identification of two overlapping ell functional domains that govern its interaction with polymerase and the ternary elongation complex Journal of Biological Chemistry. 272: 22355-22363. PMID 9268387 DOI: 10.1074/Jbc.272.35.22355  0.79
1997 Dvir A, Conaway RC, Conaway JW. A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes Proceedings of the National Academy of Sciences of the United States of America. 94: 9006-9010. PMID 9256425 DOI: 10.1073/Pnas.94.17.9006  0.806
1997 Reines D, Dvir A, Conaway JW, Conaway RC. Assays for investigating transcription by RNA polymerase II in vitro Methods: a Companion to Methods in Enzymology. 12: 192-202. PMID 9237163 DOI: 10.1006/Meth.1997.0471  0.782
1997 Conaway RC, Conaway JW. General transcription factors for RNA polymerase II Progress in Nucleic Acid Research and Molecular Biology. 56: 327-346. PMID 9187058 DOI: 10.1016/S0079-6603(08)61009-0  0.769
1997 Shilatifard A, Conaway JW, Conaway RC. Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II Current Opinion in Genetics and Development. 7: 199-204. PMID 9115429 DOI: 10.1016/S0959-437X(97)80129-3  0.791
1997 Shilatifard A, Duan DR, Haque D, Florence C, Schubach WH, Conaway JW, Conaway RC. ELL2, a new member of an ELL family of RNA polymerase II elongation factors Proceedings of the National Academy of Sciences of the United States of America. 94: 3639-3643. PMID 9108030 DOI: 10.1073/pnas.94.8.3639  0.757
1996 Pause A, Aso T, Linehan WM, Conaway JW, Conaway RC, Klausner RD. Interaction of von Hippel-Lindau tumor suppressor gene product with elongin. Methods in Enzymology. 274: 436-41. PMID 8902823 DOI: 10.1016/S0076-6879(96)74035-1  0.755
1996 Aso T, Haque D, Barstead RJ, Conaway RC, Conaway JW. The inducible elongin A elongation activation domain: Structure, function and interaction with the elongin BC complex Embo Journal. 15: 5557-5566. PMID 8896449 DOI: 10.1002/J.1460-2075.1996.Tb00940.X  0.784
1996 Reines D, Conaway JW, Conaway RC. The RNA polymerase II general elongation factors Trends in Biochemical Sciences. 21: 351-355. PMID 8870500 DOI: 10.1016/S0968-0004(96)10045-1  0.778
1996 Qadri I, Conaway JW, Conaway RC, Schaack J, Siddiqui A. Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH Proceedings of the National Academy of Sciences of the United States of America. 93: 10578-10583. PMID 8855220 DOI: 10.1073/Pnas.93.20.10578  0.739
1996 Takagi Y, Conaway RC, Conaway JW. Characterization of elongin C functional domains required for interaction with Elongin B and activation of Elongin A Journal of Biological Chemistry. 271: 25562-25568. PMID 8810329 DOI: 10.1074/Jbc.271.41.25562  0.767
1996 Dvir A, Conaway RC, Conaway JW. Promoter escape by RNA polymerase II. A role for an ATP cofactor in suppression of arrest by polymerase at promoter-proximal sites Journal of Biological Chemistry. 271: 23352-23356. PMID 8798537 DOI: 10.1074/Jbc.271.38.23352  0.795
1996 Conaway RC, Reines D, Garrett KP, Powell W, Conaway JW. Purification of RNA polymerase II general transcription factors from rat liver Methods in Enzymology. 273: 194-207. PMID 8791613 DOI: 10.1016/S0076-6879(96)73020-3  0.743
1996 Aso T, Haque D, Fukudome K, Brower CS, Conaway JW, Conaway RC. A human cDNA encoding the 110-kDa a subunit of RNA polymerase II transcription factor elongin Gene. 168: 277-278. PMID 8654961 DOI: 10.1016/0378-1119(95)00750-4  0.755
1996 Dvir A, Garrett KP, Chalut C, Egly JM, Conaway JW, Conaway RC. A role for ATP and TFIIH in activation of the RNA polymerase II preinitiation complex prior to transcription initiation Journal of Biological Chemistry. 271: 7245-7248. PMID 8631733 DOI: 10.1074/Jbc.271.13.7245  0.783
1996 Aso T, Shilatifard A, Conaway JW, Conaway RC. Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease Journal of Clinical Investigation. 97: 1561-1569. PMID 8601619 DOI: 10.1172/Jci118580  0.806
1996 Shilatifard A, Lane WS, Jackson KW, Conaway RC, Conaway JW. An RNA polymerase II elongation factor encoded by the human ELL gene Science. 271: 1873-1876. PMID 8596958 DOI: 10.1126/Science.271.5257.1873  0.772
1995 Serizawa H, Mäkelä TP, Conaway JW, Conaway RC, Weinberg RA, Young RA. Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature. 374: 280-2. PMID 7885450 DOI: 10.1038/374280A0  0.748
1995 Aso T, Lane WS, Conaway JW, Conaway RC. Elongin (SIII): A multisubunit regulator of elongation by RNA polymerase II Science. 269: 1439-1443. PMID 7660129 DOI: 10.1126/Science.7660129  0.787
1995 Garrett KP, Aso T, Bradsher JN, Foundling SI, Lane WS, Conaway RC, Conaway JW. Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog Proceedings of the National Academy of Sciences of the United States of America. 92: 7172-7176. PMID 7638163 DOI: 10.1073/Pnas.92.16.7172  0.774
1995 Tan S, Conaway RC, Conaway JW. Dissection of transcription factor TFIIF functional domains required for initiation and elongation Proceedings of the National Academy of Sciences of the United States of America. 92: 6042-6046. PMID 7597077 DOI: 10.1073/Pnas.92.13.6042  0.799
1995 Takagi Y, Conaway JW, Conaway RC. A novel activity associated with RNA polymerase II elongation factor SIII: SIII directs promoter-independent transcription initiation by RNA polymerase II in the absence of initiation factors Journal of Biological Chemistry. 270: 24300-24305. PMID 7592640 DOI: 10.1074/Jbc.270.41.24300  0.781
1995 Aso T, Conaway JW, Conaway RC. The RNA polymerase II elongation complex Faseb Journal. 9: 1419-1428. PMID 7589983 DOI: 10.1096/Fasebj.9.14.7589983  0.791
1994 Aso T, Serizawa H, Conaway RC, Conaway JW. A TATA sequence-dependent transcriptional repressor activity associated with mammalian transcription factor IIA Embo Journal. 13: 435-445. PMID 8313889 DOI: 10.1002/J.1460-2075.1994.Tb06278.X  0.787
1994 Garrett KP, Tan S, Bradsher JN, Lane WS, Conaway JW, Conaway RC. Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII Proceedings of the National Academy of Sciences of the United States of America. 91: 5237-5241. PMID 8202474 DOI: 10.1073/Pnas.91.12.5237  0.768
1994 Tan S, Garrett KP, Conaway RC, Conaway JW. Cryptic DNA-binding domain in the C terminus of RNA polymerase II general transcription factor RAP30 Proceedings of the National Academy of Sciences of the United States of America. 91: 9808-9812. PMID 7937895 DOI: 10.1073/Pnas.91.21.9808  0.703
1994 Garrett KP, Haque D, Conaway RC, Conaway JW. A human cDNA encoding the small subunit of RNA polymerase II transcription factor SIII Gene. 150: 413-414. PMID 7821821 DOI: 10.1016/0378-1119(94)90467-7  0.743
1994 Tan S, Aso T, Conaway RC, Conaway JW. Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II. Journal of Biological Chemistry. 269: 25684-25691. DOI: 10.1016/s0021-9258(18)47303-6  0.474
1994 Aso T, Conaway JW, Conaway RC. Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex. A common pathway for formation of preinitiation intermediates at many TATA and TATA-less promoters Journal of Biological Chemistry. 269: 26575-26583. DOI: 10.1016/s0021-9258(18)47233-x  0.424
1993 Serizawa H, Conaway JW, Conaway RC. Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription Nature. 363: 371-374. PMID 8497323 DOI: 10.1038/363371A0  0.782
1993 Conaway RC, Conaway JW. General initiation factors for RNA polymerase II Annual Review of Biochemistry. 62: 161-190. PMID 8352588 DOI: 10.1146/Annurev.Bi.62.070193.001113  0.787
1993 Bradsher JN, Tan S, McLaury HJ, Conaway JW, Conaway RC. RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation. Journal of Biological Chemistry. 268: 25594-25603. DOI: 10.1016/s0021-9258(19)74432-9  0.405
1993 Bradsher JN, Jackson KW, Conaway RC, Conaway JW. RNA polymerase II transcription factor SIII. I. Identification, purification, and properties. Journal of Biological Chemistry. 268: 25587-25593. DOI: 10.1016/s0021-9258(19)74431-7  0.424
1992 Tsuboi A, Conger K, Garrett KP, Conaway RC, Conaway JW, Arai N. RNA polymerase II initiation factor α from rat liver is almost identical to human TFIIB Nucleic Acids Research. 20: 3250. PMID 1620622 DOI: 10.1093/Nar/20.12.3250  0.716
1992 Serizawa H, Conaway RC, Conaway JW. A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor δ from rat liver Proceedings of the National Academy of Sciences of the United States of America. 89: 7476-7480. PMID 1386928 DOI: 10.1073/Pnas.89.16.7476  0.776
1992 Conaway J, Bradsher J, Conaway R. Mechanism of assembly of the RNA polymerase II preinitiation complex. Transcription factors delta and epsilon promote stable binding of the transcription apparatus to the initiator element. Journal of Biological Chemistry. 267: 10142-10148. DOI: 10.1016/s0021-9258(19)50211-3  0.473
1992 Conaway R, Bradsher J, Conaway J. Mechanism of assembly of the RNA polymerase II preinitiation complex. Evidence for a functional interaction between the carboxyl-terminal domain of the largest subunit of RNA polymerase II and a high molecular mass form of the TATA factor. Journal of Biological Chemistry. 267: 8464-8467. DOI: 10.1016/s0021-9258(18)42467-2  0.421
1991 Conaway RC, Garrett KP, Hanley JP, Conaway JW. Mechanism of promoter selection by RNA polymerase II: Mammalian transcription factors α and βγ promote entry of polymerase into the preinitiation complex Proceedings of the National Academy of Sciences of the United States of America. 88: 6205-6209. PMID 2068101 DOI: 10.1073/Pnas.88.14.6205  0.786
1990 Conaway JW, Conaway RC. An RNA polymerase II transcription factor shares functional properties with Escherichia coli σ70 Science. 248: 1550-1553. PMID 2193400 DOI: 10.1126/Science.2193400  0.784
1990 Conaway JW, Travis E, Conaway RC. Transcription initiated by RNA polymerase II and purified transcription factors from liver. A complex set of promoter sequences governs formation of the initial complex. Journal of Biological Chemistry. 265: 7564-7569. DOI: 10.1016/s0021-9258(19)39151-3  0.454
1990 Conaway RC, Conaway JW. Transcription initiated by RNA polymerase II and purified transcription factors from liver. Transcription factors alpha, beta gamma, and delta promote formation of intermediates in assembly of the functional preinitiation complex. Journal of Biological Chemistry. 265: 7559-7563. DOI: 10.1016/s0021-9258(19)39150-1  0.425
1990 Conaway JW, Reines D, Conaway RC. Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation. Journal of Biological Chemistry. 265: 7552-7558. DOI: 10.1016/s0021-9258(19)39149-5  0.453
1989 Conaway RC, Conaway JW. An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters. Proceedings of the National Academy of Sciences of the United States of America. 86: 7356-60. PMID 2552440 DOI: 10.1073/Pnas.86.19.7356  0.75
1989 Conaway JW, Conaway RC. A multisubunit transcription factor essential for accurate initiation by RNA polymerase II Journal of Biological Chemistry. 264: 2357-2362. DOI: 10.1016/S0021-9258(18)94184-0  0.431
1988 Conaway RC, Conaway JW. ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis. Journal of Biological Chemistry. 263: 2962-2968. DOI: 10.1016/s0021-9258(18)69162-8  0.399
1987 Conaway JW, Bond MW, Conaway RC. An RNA polymerase II transcription system from rat liver. Purification of an essential component. Journal of Biological Chemistry. 262: 8293-8297. DOI: 10.1016/s0021-9258(18)47562-x  0.348
1982 Conaway RC, Lehman IR. A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos. Proceedings of the National Academy of Sciences of the United States of America. 79: 2523-7. PMID 6806812 DOI: 10.1073/Pnas.79.8.2523  0.32
1980 Richardson JP, Conaway R. Ribonucleic acid release activity of transcription termination protein rho is dependent on the hydrolysis of nucleoside triphosphates. Biochemistry. 19: 4293-4299. PMID 6158331 DOI: 10.1021/Bi00559A022  0.389
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