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Ajit Kumar - Publications

Affiliations: 
1979-2018 Biochemistry and Molecular Biology George Washington School of Medicine and Health Sciences, Washington, D.C., United States 
Website:
https://smhs.gwu.edu/news/professors-receive-emeritus-status-md-graduation
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Bao W, Florea L, Wu N, Wang Z, Banaudha K, Qian J, Houzet L, Kumar R, Kumar A. Loss of nuclear PTEN in HCV-infected human hepatocytes. Infectious Agents and Cancer. 9: 23. PMID 25075209 DOI: 10.1186/1750-9378-9-23  0.337
2012 Laurent GS, Shtokalo D, Heydarian M, Palyanov A, Babiy D, Zhou J, Kumar A, Urcuqui-Inchima S. Insights from the HuR-interacting transcriptome: ncRNAs, ubiquitin pathways, and patterns of secondary structure dependent RNA interactions Molecular Genetics and Genomics. 287: 867-879. PMID 23052832 DOI: 10.1007/S00438-012-0722-8  0.369
2011 Hernández JC, Arteaga J, Paul S, Kumar A, Latz E, Urcuqui-Inchima S. Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens. Aids Research and Human Retroviruses. 27: 1099-1109. PMID 21406030 DOI: 10.1089/Aid.2010.0302  0.324
2011 Urcuqui-Inchima S, Patiño C, Zapata X, García MP, Arteaga J, Chamot C, Kumar A, Hernandez-Verdun D. Production of HIV particles is regulated by altering sub-cellular localization and dynamics of Rev induced by double-strand RNA binding protein. Plos One. 6: e16686. PMID 21364984 DOI: 10.1371/Journal.Pone.0016686  0.406
2011 Banaudha K, Kaliszewski M, Korolnek T, Florea L, Yeung ML, Jeang KT, Kumar A. MicroRNA silencing of tumor suppressor DLC-1 promotes efficient hepatitis C virus replication in primary human hepatocytes. Hepatology (Baltimore, Md.). 53: 53-61. PMID 20967756 DOI: 10.1002/Hep.24016  0.307
2010 Banaudha K, Orenstein JM, Korolnek T, St Laurent GC, Wakita T, Kumar A. Primary hepatocyte culture supports hepatitis C virus replication: a model for infection-associated hepatocarcinogenesis. Hepatology (Baltimore, Md.). 51: 1922-32. PMID 20512986 DOI: 10.1002/Hep.23616  0.315
2009 Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, ... ... Kumar A, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics. 41: 553-62. PMID 19377474 DOI: 10.1038/Ng.375  0.321
2008 Kumar A, Jeang KT. Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1). Journal of Cellular Physiology. 216: 327-31. PMID 18452151 DOI: 10.1002/Jcp.21488  0.335
2008 Kumar A. RNA interference: a multifaceted innate antiviral defense. Retrovirology. 5: 17-17. PMID 18241347 DOI: 10.1186/1742-4690-5-17  0.371
2007 Agbottah ET, Traviss C, McArdle J, Karki S, St Laurent GC, Kumar A. Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1. Retrovirology. 4: 41. PMID 17565699 DOI: 10.1186/1742-4690-4-41  0.442
2007 Ruggieri A, Franco M, Gatto I, Kumar A, Rapicetta M. Modulation of RANTES expression by HCV core protein in liver derived cell lines Bmc Gastroenterology. 7: 21-21. PMID 17565659 DOI: 10.1186/1471-230X-7-21  0.304
2007 Kumar A. The silent defense: Micro-RNA directed defense against HIV-1 replication Retrovirology. 4: 26-26. PMID 17430590 DOI: 10.1186/1742-4690-4-26  0.384
2006 Urcuqui-Inchima S, Castaño ME, Hernandez-Verdun D, St-Laurent G, Kumar A. Nuclear Factor 90, a cellular dsRNA binding protein inhibits the HIV Rev-export function. Retrovirology. 3: 83-83. PMID 17125513 DOI: 10.1186/1742-4690-3-83  0.444
2004 Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A. Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription. Journal of Virology. 78: 13522-33. PMID 15564463 DOI: 10.1128/Jvi.78.24.13522-13533.2004  0.402
2003 Pumfery A, Deng L, Maddukuri A, de la Fuente C, Li H, Wade JD, Lambert P, Kumar A, Kashanchi F. Chromatin remodeling and modification during HIV-1 Tat-activated transcription. Current Hiv Research. 1: 343-62. PMID 15046258 DOI: 10.2174/1570162033485186  0.394
2003 Zhou M, Deng L, Kashanchi F, Brady JN, Shatkin AJ, Kumar A. The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA. Proceedings of the National Academy of Sciences of the United States of America. 100: 12666-71. PMID 14569024 DOI: 10.1073/Pnas.1835726100  0.431
2003 Ammosova T, Jerebtsova M, Beullens M, Voloshin Y, Ray PE, Kumar A, Bollen M, Nekhai S. Nuclear protein phosphatase-1 regulates HIV-1 transcription. The Journal of Biological Chemistry. 278: 32189-94. PMID 12788939 DOI: 10.1074/Jbc.M300521200  0.412
2003 Marques SM, Veyrune JL, Shukla RR, Kumar A. Restriction of human immunodeficiency virus type 1 Rev function in murine A9 cells involves the Rev C-terminal domain. Journal of Virology. 77: 3084-90. PMID 12584334 DOI: 10.1128/Jvi.77.5.3084-3090.2003  0.356
2002 Washington K, Ammosova T, Beullens M, Jerebtsova M, Kumar A, Bollen M, Nekhai S. Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. The Journal of Biological Chemistry. 277: 40442-8. PMID 12185079 DOI: 10.1074/Jbc.M205687200  0.404
2002 Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. The Biochemical Journal. 364: 649-57. PMID 12049628 DOI: 10.1042/Bj20011191  0.435
2002 Krasnoselskaya-Riz I, Spruill A, Chen YW, Schuster D, Teslovich T, Baker C, Kumar A, Stephan DA. Nuclear factor 90 mediates activation of the cellular antiviral expression cascade. Aids Research and Human Retroviruses. 18: 591-604. PMID 12036489 DOI: 10.1089/088922202753747941  0.409
2002 Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A. A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat. Virology. 296: 6-16. PMID 12036313 DOI: 10.1006/Viro.2002.1438  0.444
2001 Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN. TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription. The Journal of Biological Chemistry. 276: 44633-40. PMID 11572868 DOI: 10.1074/Jbc.M107466200  0.406
2000 Nekhai S, Shukla RR, Fernandez A, Kumar A, Lamb NJ. Cell cycle-dependent stimulation of the HIV-1 promoter by Tat-associated CAK activator. Virology. 266: 246-56. PMID 10639311 DOI: 10.1006/Viro.1999.0035  0.416
2000 Kashanchi F, Agbottah ET, Pise-Masison CA, Mahieux R, Duvall J, Kumar A, Brady JN. Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator. Journal of Virology. 74: 652-60. PMID 10623726 DOI: 10.1128/Jvi.74.2.652-660.2000  0.4
1997 Nekhai S, Shukla RR, Kumar A. A human primary T-lymphocyte-derived human immunodeficiency virus type 1 Tat-associated kinase phosphorylates the C-terminal domain of RNA polymerase II and induces CAK activity. Journal of Virology. 71: 7436-41. PMID 9311822 DOI: 10.1128/Jvi.71.10.7436-7441.1997  0.351
1996 Shukla RR, Marques SM, Kimmel PL, Kumar A. Human chromosome 6- and 11-encoded factors support human immunodeficiency virus type 1 Rev function in A9 cells. Journal of Virology. 70: 9064-8. PMID 8971045 DOI: 10.1128/Jvi.70.12.9064-9068.1996  0.409
1996 Nekhai S, Kumar A, Bottaro DP, Petryshyn R. Peptides Derived from the Interferon-Induced PKR Prevent Activation by HIV-1 TAR RNA Virology. 222: 193-200. PMID 8806499 DOI: 10.1006/Viro.1996.0410  0.4
1996 Rounseville MP, Lin HC, Agbottah E, Shukla RR, Rabson AB, Kumar A. Inhibition of HIV-1 replication in viral mutants with altered TAR RNA stem structures. Virology. 216: 411-7. PMID 8607271 DOI: 10.1006/Viro.1996.0077  0.401
1994 Shukla RR, Kimmel PL, Kumar A. Human immunodeficiency virus type 1 Rev-responsive element RNA binds to host cell-specific proteins Journal of Virology. 68: 2224-2229. PMID 8139007 DOI: 10.1128/Jvi.68.4.2224-2229.1994  0.409
1993 Shukla RR, Kumar A, Kimmel PL. Transforming growth factor beta increases the expression of HIV-1 gene in transfected human mesangial cells Kidney International. 44: 1022-1029. PMID 8264131 DOI: 10.1038/Ki.1993.344  0.346
1992 Han XM, Laras A, Rounseville MP, Kumar A, Shank PR. Human immunodeficiency virus type 1 Tat-mediated trans activation correlates with the phosphorylation state of a cellular TAR RNA stem-binding factor Journal of Virology. 66: 4065-4072. PMID 1602533 DOI: 10.1128/Jvi.66.7.4065-4072.1992  0.426
1989 Gatignol A, Kumar A, Rabson A, Jeang KT. Identification of cellular proteins that bind to the human immunodeficiency virus type 1 trans-activation-responsive TAR element RNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 7828-32. PMID 2510154 DOI: 10.1073/Pnas.86.20.7828  0.453
1988 Siegall CB, Hla TT, Kumar A. Reconstituted U1 small nuclear ribonucleoprotein complex restores 5' splice site cleavage activity. Biochemical and Biophysical Research Communications. 154: 1010-7. PMID 2970258 DOI: 10.1016/0006-291X(88)90240-9  0.514
1988 Jeang KT, Shank PR, Kumar A. Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis Proceedings of the National Academy of Sciences of the United States of America. 85: 8291-8295. PMID 2847157 DOI: 10.1073/Pnas.85.21.8291  0.425
1988 Siegall CB, Kumar A. Differential enzymatic accessibilities of the 5' and 3' splice sites of β-globin pre-messenger RNA in splicing competent HeLa cell nuclear extract Biochemical and Biophysical Research Communications. 150: 517-525. PMID 2829876 DOI: 10.1016/0006-291X(88)90424-X  0.361
1986 Hla T, Farrell M, Kumar A, Bailey JM. Isolation of the cDNA for human prostaglandin H synthase. Prostaglandins. 32: 829-45. PMID 3104990 DOI: 10.1016/0090-6980(86)90093-6  0.596
1984 Connaughton JF, Rairkar A, Lockard RE, Kumar A. Primary structure of rabbit 18S ribosomal RNA determined by direct RNA sequence analysis. Nucleic Acids Research. 12: 4731-45. PMID 6330682 DOI: 10.1093/Nar/12.11.4731  0.367
1982 Lockard RE, Connaughton JF, Kumar A. Nucleotide sequence of the 5′-and 3′-domains for rabbit 18S ribosomal RNA Nucleic Acids Research. 10: 3445-3457. PMID 7048256 DOI: 10.1093/Nar/10.11.3445  0.358
1980 Sajdel-Sulkowska E, Kumar A. Metabolism of poly(A) sequences during 3T3 cell growth regulation Biochimica Et Biophysica Acta. 610: 147-157. PMID 7437438 DOI: 10.1016/0005-2787(80)90064-7  0.362
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