James Connor - Publications

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224 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ebea-Ugwuanyi PO, Vidyasagar S, Connor JR, Frazer DM, Knutson MD, Collins JF. Oral iron therapy: Current concepts and future prospects for improving efficacy and outcomes. British Journal of Haematology. PMID 38253961 DOI: 10.1111/bjh.19268  0.36
2023 Troike KM, Wang SZ, Silver DJ, Lee J, Mulkearns-Hubert EE, Hajdari N, Ghosh PK, Kay KE, Beilis JL, Mitchell SE, Bishop CW, Hong ES, Artomov M, Hubert CG, Rajappa P, ... Connor JR, et al. Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses. Neuro-Oncology Advances. 6: vdad154. PMID 38239626 DOI: 10.1093/noajnl/vdad154  0.366
2023 Palsa K, Neely EB, Baringer SL, Helmuth TB, Simpson IA, Connor JR. Brain iron acquisition depends on age and sex in iron-deficient mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23331. PMID 38031991 DOI: 10.1096/fj.202301596RR  0.405
2023 Shenoy G, Kheirabadi S, Ataie Z, Sahu AP, Palsa K, Wade Q, Khunsriraksakul C, Khristov V, Slagle-Webb B, Lathia JD, Wang HG, Sheikhi A, Connor JR. Iron inhibits glioblastoma cell migration and polarization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e23307. PMID 37983646 DOI: 10.1096/fj.202202157RR  0.378
2023 Pandya Shesh B, Walter V, Palsa K, Slagle-Webb B, Neely E, Schell T, Connor JR. Sexually dimorphic effect of H-ferritin genetic manipulation on survival and tumor microenvironment in a mouse model of glioblastoma. Journal of Neuro-Oncology. 164: 569-586. PMID 37812288 DOI: 10.1007/s11060-023-04415-2  0.334
2023 Helmuth TB, Kumari R, Palsa K, Neely EB, Slagle-Webb B, Simon SD, Connor JR. Common Mutation in the Gene Modifies Recovery After Intracerebral Hemorrhage. Stroke. PMID 37750297 DOI: 10.1161/STROKEAHA.123.043799  0.35
2023 Baringer SL, Lukacher AS, Palsa K, Kim H, Lippmann ES, Spiegelman VS, Simpson IA, Connor JR. Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin. Journal of Neurochemistry. PMID 37667496 DOI: 10.1111/jnc.15954  0.418
2023 Shenoy G, Connor JR. A Closer Look at the Role of Iron in Glioblastoma. Neuro-Oncology. PMID 37539622 DOI: 10.1093/neuonc/noad136  0.4
2023 Baringer SL, Lukacher AS, Palsa K, Kim H, Lippmann ES, Spiegelman VS, Simpson IA, Connor JR. Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin. Biorxiv : the Preprint Server For Biology. PMID 37292926 DOI: 10.1101/2023.05.15.540795  0.416
2023 Baringer SL, Palsa K, Spiegelman VS, Simpson IA, Connor JR. Apo- and holo-transferrin differentially interact with hephaestin and ferroportin in a novel mechanism of cellular iron release regulation. Journal of Biomedical Science. 30: 36. PMID 37277838 DOI: 10.1186/s12929-023-00934-2  0.4
2023 Pandya Shesh B, Slagle-Webb B, Shenoy G, Khristov V, Zacharia BE, Connor JR. Uptake of H-ferritin by Glioblastoma stem cells and its impact on their invasion capacity. Journal of Cancer Research and Clinical Oncology. PMID 37237166 DOI: 10.1007/s00432-023-04864-2  0.382
2023 Baringer SL, Simpson IA, Connor JR. Brain iron acquisition: An overview of homeostatic regulation and disease dysregulation. Journal of Neurochemistry. PMID 37000124 DOI: 10.1111/jnc.15819  0.403
2023 Baringer SL, Palsa K, Simpson IA, Connor JR. Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier. Biorxiv : the Preprint Server For Biology. PMID 36712094 DOI: 10.1101/2023.01.10.522344  0.406
2023 Baringer S, Palsa K, Simpson IA, Connor JR. Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier. Research Square. PMID 36711476 DOI: 10.21203/rs.3.rs-2429356/v1  0.39
2023 Palsa K, Connor JR, Flanagan J, Hines EA. H- ferritin in sows' colostrum and milk-derived extracellular vesicles: a novel iron delivery concept. Journal of Animal Science. PMID 36629252 DOI: 10.1093/jas/skad013  0.374
2023 Palsa K, Baringer SL, Shenoy G, Simpson IA, Connor JR. Exosomes are involved in iron transport from human blood-brain barrier endothelial cells and are modified by endothelial cell iron status. The Journal of Biological Chemistry. 102868. PMID 36603765 DOI: 10.1016/j.jbc.2022.102868  0.419
2022 Baringer SL, Neely EB, Palsa K, Simpson IA, Connor JR. Regulation of brain iron uptake by apo- and holo-transferrin is dependent on sex and delivery protein. Fluids and Barriers of the Cns. 19: 49. PMID 35689283 DOI: 10.1186/s12987-022-00345-9  0.402
2021 Jellen LC, Lewis MM, Du G, Wang X, Galvis MLE, Krzyzanowski S, Capan CD, Snyder AM, Connor JR, Kong L, Mailman RB, Brundin P, Brundin L, Huang X. Low plasma serotonin linked to higher nigral iron in Parkinson's disease. Scientific Reports. 11: 24384. PMID 34934078 DOI: 10.1038/s41598-021-03700-2  0.706
2021 Lee SY, Slagle-Webb B, Schengrund CL, Zhu J, Connor JR. Association Between Iron and Cholesterol in Neuroblastomas. Anticancer Research. 41: 2795-2804. PMID 34083269 DOI: 10.21873/anticanres.15060  0.347
2021 Wang EW, Trojano ML, Lewis MM, Du G, Chen H, Brown GL, Jellen LC, Song I, Neely E, Kong L, Connor JR, Huang X. HFE H63D limits nigral vulnerability to paraquat in agricultural workers. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 33739421 DOI: 10.1093/toxsci/kfab020  0.336
2020 Kim Y, Connor JR. The roles of iron and HFE genotype in neurological diseases. Molecular Aspects of Medicine. 100867. PMID 32654761 DOI: 10.1016/j.mam.2020.100867  0.428
2020 Song I, Snyder AM, Kim Y, Neely EB, Wade QW, Connor JR. The Nrf2-mediated defense mechanism associated with HFE genotype limits vulnerability to oxidative stress-induced toxicity. Toxicology. 152525. PMID 32540480 DOI: 10.1016/J.Tox.2020.152525  0.691
2020 Connor JR, Duck K, Patton S, Simpson IA, Trotti LM, Allen R, Earley CJ, Rye D. Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy. Fluids and Barriers of the Cns. 17: 28. PMID 32295615 DOI: 10.1186/S12987-020-00190-8  0.39
2019 Chiou B, Neely EB, Mcdevitt DS, Simpson IA, Connor JR. Transferrin and H-ferritin involvement in brain iron acquisition during postnatal development: impact of sex and genotype. Journal of Neurochemistry. PMID 31339576 DOI: 10.1111/jnc.14834  0.432
2019 Wade QW, Chiou B, Connor JR. Iron uptake at the blood-brain barrier is influenced by sex and genotype. Advances in Pharmacology (San Diego, Calif.). 84: 123-145. PMID 31229168 DOI: 10.1016/bs.apha.2019.02.005  0.393
2019 Möller HE, Bossoni L, Connor JR, Crichton RR, Does MD, Ward RJ, Zecca L, Zucca FA, Ronen I. Iron, Myelin, and the Brain: Neuroimaging Meets Neurobiology. Trends in Neurosciences. PMID 31047721 DOI: 10.1016/J.Tins.2019.03.009  0.417
2019 Lee S, Walter V, Salzberg A, Nesterova D, Lathia J, Rubin J, Berens M, Barnholtz-Sloan J, Connor J. EPID-01. SEX DIFFERENCE IN EXPRESSION OF IRON-RELATED GENES AND SURVIVAL IN GLIOBLASTOMA PATIENTS Neuro-Oncology. 21: vi74-vi74. DOI: 10.1093/Neuonc/Noz175.301  0.356
2019 Pandya B, Ravi V, Connor J. TMIC-43. ROLE OF EXTRACELLULAR FERRITIN HEAVY CHAIN PROTEIN IN GLIOBLASTOMA MULTIFORME Neuro-Oncology. 21: vi257-vi257. DOI: 10.1093/neuonc/noz175.1077  0.386
2019 Shenoy G, Madhankumar A, Slagle-Webb B, Mrowczynski O, Schell T, Nesterova D, Lee S, Davalos D, Berens M, Lathia J, Barnholtz-Sloan J, Rubin J, Connor J. TMIC-31. IMPACT OF IRON ON MACROPHAGE IMMUNE PHENOTYPE IN THE GLIOBLASTOMA TUMOR MICROENVIRONMENT Neuro-Oncology. 21: vi254-vi254. DOI: 10.1093/Neuonc/Noz175.1065  0.39
2018 Chiou B, Connor JR. Emerging and Dynamic Biomedical Uses of Ferritin. Pharmaceuticals (Basel, Switzerland). 11. PMID 30428583 DOI: 10.3390/ph11040124  0.38
2018 Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR. Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18783372. PMID 29911470 DOI: 10.1177/0271678X18783372  0.417
2018 Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR. Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier. Plos One. 13: e0198775. PMID 29889872 DOI: 10.1371/Journal.Pone.0198775  0.425
2018 Lewis MM, Du G, Baccon J, Snyder AM, Murie B, Cooper F, Stetter C, Kong L, Sica C, Mailman RB, Connor JR, Huang X. Susceptibility MRI captures nigral pathology in patients with parkinsonian syndromes. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29756231 DOI: 10.1002/Mds.27381  0.641
2018 Briones MRS, Snyder AM, Ferreira RC, Neely EB, Connor JR, Broach JR. A Possible Role for Platelet-Activating Factor Receptor in Amyotrophic Lateral Sclerosis Treatment. Frontiers in Neurology. 9: 39. PMID 29472887 DOI: 10.3389/Fneur.2018.00039  0.628
2018 Chiou B, Lucassen E, Sather M, Kallianpur A, Connor J. Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis. Glia. PMID 29457657 DOI: 10.1002/glia.23313  0.409
2018 Allen RP, Picchietti DL, Auerbach M, Cho YW, Connor JR, Earley CJ, Garcia-Borreguero D, Kotagal S, Manconi M, Ondo W, Ulfberg J, Winkelman JW. Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report. Sleep Medicine. 41: 27-44. PMID 29425576 DOI: 10.1016/J.Sleep.2017.11.1126  0.319
2018 Peters DG, Pollack AN, Cheng KC, Sun D, Saido T, Haaf MP, Yang QX, Connor JR, Meadowcroft MD. Dietary lipophilic iron alters amyloidogenesis and microglial morphology in Alzheimer's disease knock-in APP mice. Metallomics : Integrated Biometal Science. PMID 29424844 DOI: 10.1039/C8Mt00004B  0.831
2018 Nixon AM, Neely E, Simpson IA, Connor JR. The role of HFE genotype in macrophage phenotype. Journal of Neuroinflammation. 15: 30. PMID 29391061 DOI: 10.1186/s12974-018-1057-0  0.379
2018 Meadowcroft MD, Cooper TK, Rupprecht S, Wright TC, Neely EE, Ferenci M, Kang W, Yang QX, Harbaugh RE, Connor JR, McInerney J. Gamma Knife radiosurgery of saccular aneurysms in a rabbit model. Journal of Neurosurgery. 1-11. PMID 29328001 DOI: 10.3171/2017.6.Jns17722  0.677
2018 Nixon AM, Meadowcroft MD, Neely EB, Snyder AM, Purnell CJ, Wright J, Lamendella R, Nandar W, Huang X, Connor JR. HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity. Journal of Neurochemistry. PMID 29315562 DOI: 10.1111/Jnc.14299  0.798
2017 Peters DG, Purnell CJ, Haaf MP, Yang QX, Connor JR, Meadowcroft MD. Dietary lipophilic iron accelerates regional brain iron-load in C57BL6 mice. Brain Structure & Function. PMID 29168009 DOI: 10.1007/S00429-017-1565-1  0.829
2017 Duck KA, Simpson IA, Connor JR. Regulatory mechanisms for iron transport across the blood-brain barrier. Biochemical and Biophysical Research Communications. PMID 29054412 DOI: 10.1016/j.bbrc.2017.10.083  0.415
2017 Folarin OR, Snyder AM, Peters DG, Olopade F, Connor JR, Olopade JO. Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice. Frontiers in Neuroanatomy. 11: 58. PMID 28790895 DOI: 10.3389/fnana.2017.00058  0.737
2017 Meadowcroft MD, Wang J, Purnell CJ, Eslinger PJ, Neely EB, Yang QX, Connor JR. Reduced Cerebral White Matter Integrity Assessed by DTI in Cognitively Normal H63D-HFE Polymorphism Carriers. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 28771940 DOI: 10.1111/Jon.12461  0.729
2017 Madhankumar AB, Mrowczynski O, Patel S, Weston C, Zacharia B, Glantz M, Siedlecki C, Xu L, Connor JR. Interleukin-13 conjugated quantum dots for identification of glioma initiating cells and their extracellular vesicles. Acta Biomaterialia. PMID 28583903 DOI: 10.1016/J.Actbio.2017.06.002  0.662
2017 Mehta SR, Pérez-Santiago J, Hulgan T, Day TR, Barnholtz-Sloan J, Gittleman H, Letendre S, Ellis R, Heaton R, Patton S, Suben JD, Franklin D, Rosario D, Clifford DB, Collier AC, ... ... Connor J, et al. Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment. Journal of Neuroinflammation. 14: 72. PMID 28359324 DOI: 10.1186/S12974-017-0848-Z  0.318
2017 Duck KA, Neely EB, Simpson IA, Connor JR. A role for sex and a common HFE gene variant in brain iron uptake. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17701949. PMID 28350201 DOI: 10.1177/0271678X17701949  0.418
2016 Connor JR, Patton SM, Oexle K, Allen R. Iron and restless legs syndrome: treatment, genetics and pathophysiology. Sleep Medicine. PMID 28057495 DOI: 10.1016/j.sleep.2016.07.028  0.407
2016 Schieffer KM, Chuang CH, Connor J, Pawelczyk JA, Sekhar DL. Association of Iron Deficiency Anemia With Hearing Loss in US Adults. Jama Otolaryngology-- Head & Neck Surgery. PMID 28033450 DOI: 10.1001/Jamaoto.2016.3631  0.358
2016 Bastian TW, Duck KA, Michalopoulos GC, Chen MJ, Liu ZJ, Connor JR, Lanier LM, Sola-Visner MC, Georgieff MK. Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain-barrier and impairs iron-dependent hippocampal neuron dendrite development. Journal of Thrombosis and Haemostasis : Jth. PMID 28005311 DOI: 10.1111/Jth.13602  0.306
2016 Weston C, Klobusicky J, Weston J, Connor J, Toms SA, Marko NF. Aberrations in the Iron Regulatory Gene Signature Are Associated with Decreased Survival in Diffuse Infiltrating Gliomas. Plos One. 11: e0166593. PMID 27898674 DOI: 10.1371/journal.pone.0166593  0.753
2016 Usende IL, Leitner DF, Neely E, Connor JR, Olopade JO. The Deterioration Seen in Myelin Related Morphophysiology in Vanadium Exposed Rats is Partially Protected by Concurrent Iron Deficiency. Nigerian Journal of Physiological Sciences : Official Publication of the Physiological Society of Nigeria. 31: 11-22. PMID 27574759  0.352
2016 Duck KA, Connor JR. Iron uptake and transport across physiological barriers. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 27457588 DOI: 10.1007/s10534-016-9952-2  0.37
2016 Hare DJ, Raven EP, Roberts BR, Bogeski M, Portbury SD, McLean CA, Masters CL, Connor JR, Bush AI, Crouch PJ, Doble PA. Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and grey matter iron distribution in Alzheimer's disease frontal cortex. Neuroimage. PMID 27233149 DOI: 10.1016/J.Neuroimage.2016.05.057  0.412
2016 Lee EY, Flynn MR, Du G, Li Y, Lewis MM, Herring AH, Van Buren E, Van Buren S, Kong L, Fry RC, Snyder AM, Connor JR, Yang QX, Mailman RB, Huang X. Increased R2* in the caudate nucleus of asymptomatic welders. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26769335 DOI: 10.1093/Toxsci/Kfw003  0.664
2015 Meadowcroft MD, Wang J, Purnell CJ, Peters DG, Eslinger PJ, Neely EB, Gill DJ, Vasavada M, Ali-Rahmani F, Yang QX, Connor JR. Reduced white matter MRI transverse relaxation rate in cognitively normal H63D-HFE human carriers and H67D-HFE mice. Brain Imaging and Behavior. PMID 26660104 DOI: 10.1007/S11682-015-9494-1  0.768
2015 Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, ... ... Connor JR, et al. Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. Cancer Cell. 28: 441-55. PMID 26461092 DOI: 10.1016/J.Ccell.2015.09.002  0.38
2015 Du G, Liu T, Lewis MM, Kong L, Wang Y, Connor J, Mailman RB, Huang X. Quantitative susceptibility mapping of the midbrain in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26362242 DOI: 10.1002/mds.26417  0.384
2015 Peters DG, Connor JR, Meadowcroft MD. The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin. Neurobiology of Disease. 81: 49-65. PMID 26303889 DOI: 10.1016/J.Nbd.2015.08.007  0.827
2015 Zhao L, Hadziahmetovic M, Wang C, Xu X, Song Y, Jinnah HA, Wodzinska J, Iacovelli J, Wolkow N, Krajacic P, Cwanger Weissberger A, Connelly J, Spino M, Lee MK, Connor J, et al. Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. Journal of Neurochemistry. PMID 26303407 DOI: 10.1111/Jnc.13292  0.513
2015 Leitner DF, Stoute JA, Landmesser M, Neely E, Connor JR. The HFE genotype and a formulated diet controlling for iron status attenuate experimental cerebral malaria in mice. International Journal For Parasitology. 45: 797-808. PMID 26296689 DOI: 10.1016/j.ijpara.2015.07.003  0.328
2015 Meadowcroft MD, Connor JR, Yang QX. Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective. Frontiers in Neuroscience. 9: 255. PMID 26257600 DOI: 10.3389/Fnins.2015.00255  0.781
2015 Mairuae N, Connor JR, Lee SY, Cheepsunthorn P, Tongjaroenbuangam W. The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line. Neuroscience Letters. 603: 6-11. PMID 26170247 DOI: 10.1016/J.Neulet.2015.07.011  0.747
2015 Leitner DF, Todorich B, Zhang X, Connor JR. Semaphorin4A Is Cytotoxic to Oligodendrocytes and Is Elevated in Microglia and Multiple Sclerosis. Asn Neuro. 7. PMID 26024919 DOI: 10.1177/1759091415587502  0.379
2015 Connor JR, Zhang X, Nixon AM, Webb B, Perno JR. Comparative evaluation of nephrotoxicity and management by macrophages of intravenous pharmaceutical iron formulations. Plos One. 10: e0125272. PMID 25973894 DOI: 10.1371/journal.pone.0125272  0.301
2015 Meadowcroft MD, Peters DG, Dewal RP, Connor JR, Yang QX. The effect of iron in MRI and transverse relaxation of amyloid-beta plaques in Alzheimer's disease. Nmr in Biomedicine. 28: 297-305. PMID 25530083 DOI: 10.1002/Nbm.3247  0.817
2015 Su XW, Clardy SL, Stephens HE, Simmons Z, Connor JR. Serum ferritin is elevated in amyotrophic lateral sclerosis patients. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 16: 102-7. PMID 25521651 DOI: 10.3109/21678421.2014.984723  0.645
2015 Simpson IA, Ponnuru P, Klinger ME, Myers RL, Devraj K, Coe CL, Lubach GR, Carruthers A, Connor JR. A novel model for brain iron uptake: introducing the concept of regulation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 48-57. PMID 25315861 DOI: 10.1038/Jcbfm.2014.168  0.432
2015 Meadowcroft MD, Mutic NJ, Bigler DC, Wang JL, Simmons Z, Connor JR, Yang QX. Histological-MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis. Journal of Magnetic Resonance Imaging : Jmri. 41: 665-75. PMID 24615949 DOI: 10.1002/Jmri.24582  0.69
2015 Madhankumar A, Mrowczynski O, Patel S, Rizk E, Weston C, Glantz M, Xu L, Siedlecki C, Connor J. TMIC-01TUMOR TARGETED QUANTUM DOTS TO IDENTIFY GLIOMA INITIATING CELLS AND EXOSOMES Neuro-Oncology. 17: v214.5-v214. DOI: 10.1093/Neuonc/Nov236.01  0.684
2015 Weston C, Klobusicky J, Connor J, Toms S, Marko N. MPTH-20ALTERATIONS IN THE IRON REGULATORY GENE SIGNATURE ARE ASSOCIATED WITH DECREASED SURVIVAL IN LOW GRADE GLIOMA Neuro-Oncology. 17: v142.3-v142. DOI: 10.1093/neuonc/nov222.20  0.311
2015 Peters DG, Connor JR, Meadowcroft MD. The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin Neurobiology of Disease. DOI: 10.1016/j.nbd.2015.08.007  0.808
2015 Meadowcroft MD, Peters DG, Purnell CJ, Wang J, Eslinger PJ, Yang QX, Connor JR. P2-121: Differential MRI relaxation in Alzheimer's patients with mutant hfe and transferrin genotypes Alzheimer's & Dementia. 11: P528-P529. DOI: 10.1016/j.jalz.2015.06.659  0.756
2015 Meadowcroft MD, Peters DG, Haaf MP, Yang QX, Connor JR. P1-162: Magnetic resonance imaging of APP/PS1/Tau mice on gradated iron diets Alzheimer's & Dementia. 11: P407-P407. DOI: 10.1016/j.jalz.2015.06.361  0.787
2015 Meadowcroft MD, Peters DG, Haaf MP, Yang QX, Connor JR. IC-P-029: Magnetic resonance imaging of APP/PS1/Tau mice on gradated iron diets Alzheimer's & Dementia. 11: P29-P29. DOI: 10.1016/J.Jalz.2015.06.049  0.784
2015 Meadowcroft MD, Peters DG, Purnell CJ, Wang J, Eslinger PJ, Yang QX, Connor JR. IC-P-028: Differential MRI relaxation in Alzheimer's patients with mutant hfe and transferrin genotypes Alzheimer's & Dementia. 11: P28-P29. DOI: 10.1016/J.Jalz.2015.06.048  0.753
2015 Coe CL, Lubach GR, Kling P, Georgieff M, Rao R, Connor J. Iron biology is key to understanding how inflammation, stress and obesity affect maternal and child health Brain Behavior and Immunity. 49. DOI: 10.1016/J.Bbi.2015.06.132  0.485
2014 Weston C, Connor J. Evidence for the Influence of the Iron Regulatory MHC Class I Molecule HFE on Tumor Progression in Experimental Models and Clinical Populations. Translational Oncogenomics. 6: 1-12. PMID 25520556 DOI: 10.4137/Tog.S19064  0.755
2014 Earley CJ, Connor J, Garcia-Borreguero D, Jenner P, Winkelman J, Zee PC, Allen R. Altered Brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis-Ekbom Disease). Sleep Medicine. 15: 1288-301. PMID 25201131 DOI: 10.1016/J.Sleep.2014.05.009  0.494
2014 Peters DG, Connor JR. Introduction to cells comprising the nervous system. Advances in Neurobiology. 9: 33-45. PMID 25151373 DOI: 10.1007/978-1-4939-1154-7_2  0.499
2014 Ali-Rahmani F, Schengrund CL, Connor JR. HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease. Frontiers in Pharmacology. 5: 165. PMID 25071582 DOI: 10.3389/fphar.2014.00165  0.373
2014 Pang M, Liu X, Madhankumar AB, Slagle-Webb B, Connor J. RT-40 * THE DOWN-REGULATION OF H-FERRITIN AS AN ADJUVANT THERAPY IN HUMAN GLIOMA Neuro-Oncology. 16: v196-v196. DOI: 10.1093/Neuonc/Nou270.36  0.495
2013 Su XW, Simmons Z, Mitchell RM, Kong L, Stephens HE, Connor JR. Biomarker-based predictive models for prognosis in amyotrophic lateral sclerosis. Jama Neurology. 70: 1505-11. PMID 24145899 DOI: 10.1001/Jamaneurol.2013.4646  0.466
2013 Su XW, Lee SY, Mitchell RM, Stephens HE, Simmons Z, Connor JR. H63D HFE polymorphisms are associated with increased disease duration and decreased muscle superoxide dismutase-1 expression in amyotrophic lateral sclerosis patients. Muscle & Nerve. 48: 242-6. PMID 23813494 DOI: 10.1002/Mus.23740  0.488
2013 Nandar W, Neely EB, Unger E, Connor JR. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice. Biochimica Et Biophysica Acta. 1832: 729-41. PMID 23429074 DOI: 10.1016/j.bbadis.2013.02.009  0.356
2013 Rao R, Tkac I, Unger EL, Ennis K, Hurst A, Schallert T, Connor J, Felt B, Georgieff MK. Iron supplementation dose for perinatal iron deficiency differentially alters the neurochemistry of the frontal cortex and hippocampus in adult rats. Pediatric Research. 73: 31-7. PMID 23095980 DOI: 10.1038/Pr.2012.143  0.484
2012 Patton SM, Coe CL, Lubach GR, Connor JR. Quantitative proteomic analyses of cerebrospinal fluid using iTRAQ in a primate model of iron deficiency anemia. Developmental Neuroscience. 34: 354-65. PMID 23018452 DOI: 10.1159/000341919  0.417
2012 Unger EL, Hurst AR, Georgieff MK, Schallert T, Rao R, Connor JR, Kaciroti N, Lozoff B, Felt B. Behavior and monoamine deficits in prenatal and perinatal iron deficiency are not corrected by early postnatal moderate-iron or high-iron diets in rats. The Journal of Nutrition. 142: 2040-9. PMID 22990465 DOI: 10.3945/Jn.112.162198  0.386
2012 Leitner DF, Connor JR. Functional roles of transferrin in the brain. Biochimica Et Biophysica Acta. 1820: 393-402. PMID 22138408 DOI: 10.1016/j.bbagen.2011.10.016  0.42
2012 Wiley NJ, Madhankumar AB, Mitchell RM, Neely EB, Rizk E, Douds GL, Simmons Z, Connor JR. Lipopolysaccharide Modified Liposomes for Amyotropic Lateral Sclerosis Therapy: Efficacy in SOD1 Mouse Model Advances in Nanoparticles. 1: 44-53. DOI: 10.4236/Anp.2012.13007  0.477
2012 Alkhateeb AA, Zubritsky L, Leitzel K, Ali SM, Campbell-Baird C, Koestler W, Fuchs E, Lipton A, Connor J. Abstract 391: Serum ferritin predicts response to trastuzumab and is a biomarker for breast and pancreatic cancers: A potential novel inflammatory effector mechanism Cancer Research. 72: 391-391. DOI: 10.1158/1538-7445.Am2012-391  0.369
2012 Pang M, Liu X, Madhankumar AB, Connor J. Abstract 1471: Role of ferritin heavy chain in therapeutic sensitivity of human glioblastoma cells Cancer Research. 72: 1471-1471. DOI: 10.1158/1538-7445.Am2012-1471  0.509
2011 Patton SM, Ponnuru P, Snyder AM, Podskalny GD, Connor JR. Hypoxia-inducible factor pathway activation in restless legs syndrome patients. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 18: 1329-35. PMID 21985026 DOI: 10.1111/J.1468-1331.2011.03397.X  0.71
2011 Mairuae N, Connor JR, Cheepsunthorn P. Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia. Neuroscience Letters. 500: 36-40. PMID 21683124 DOI: 10.1016/J.Neulet.2011.06.001  0.784
2011 Connor JR, Ponnuru P, Lee BY, Podskalny GD, Alam S, Allen RP, Earley CJ, Yang QX. Postmortem and imaging based analyses reveal CNS decreased myelination in restless legs syndrome. Sleep Medicine. 12: 614-9. PMID 21570342 DOI: 10.1016/j.sleep.2010.10.009  0.306
2011 Todorich B, Zhang X, Connor JR. H-ferritin is the major source of iron for oligodendrocytes. Glia. 59: 927-35. PMID 21446040 DOI: 10.1002/glia.21164  0.373
2011 Connor JR, Ponnuru P, Wang XS, Patton SM, Allen RP, Earley CJ. Profile of altered brain iron acquisition in restless legs syndrome. Brain : a Journal of Neurology. 134: 959-68. PMID 21398376 DOI: 10.1093/brain/awr012  0.378
2011 Bartzokis G, Lu PH, Tingus K, Peters DG, Amar CP, Tishler TA, Finn JP, Villablanca P, Altshuler LL, Mintz J, Neely E, Connor JR. Gender and iron genes may modify associations between brain iron and memory in healthy aging. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1375-84. PMID 21389980 DOI: 10.1038/Npp.2011.22  0.638
2011 Liu X, Madhankumar AB, Slagle-Webb B, Sheehan JM, Surguladze N, Connor JR. Heavy chain ferritin siRNA delivered by cationic liposomes increases sensitivity of cancer cells to chemotherapeutic agents. Cancer Research. 71: 2240-9. PMID 21385903 DOI: 10.1158/0008-5472.Can-10-1375  0.394
2011 Weston CL, Glantz MJ, Connor JR. Detection of cancer cells in the cerebrospinal fluid: current methods and future directions. Fluids and Barriers of the Cns. 8: 14. PMID 21371327 DOI: 10.1186/2045-8118-8-14  0.676
2011 Nandar W, Connor JR. HFE gene variants affect iron in the brain. The Journal of Nutrition. 141: 729S-739S. PMID 21346098 DOI: 10.3945/jn.110.130351  0.382
2011 Ali-Rahmani F, Hengst JA, Connor JR, Schengrund CL. Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells. Neurochemical Research. 36: 1687-96. PMID 21243428 DOI: 10.1007/S11064-011-0403-8  0.304
2011 Lee SY, Liu S, Mitchell RM, Slagle-Webb B, Hong YS, Sheehan JM, Connor JR. HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A. International Journal of Cancer. Journal International Du Cancer. 129: 2104-14. PMID 21190189 DOI: 10.1002/Ijc.25888  0.533
2011 Hadziahmetovic M, Song Y, Ponnuru P, Iacovelli J, Hunter A, Haddad N, Beard J, Connor JR, Vaulont S, Dunaief JL. Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. Investigative Ophthalmology & Visual Science. 52: 109-18. PMID 20811044 DOI: 10.1167/Iovs.10-6113  0.335
2011 Todorich B, Olopade JO, Surguladze N, Zhang X, Neely E, Connor JR. The mechanism of vanadium-mediated developmental hypomyelination is related to destruction of oligodendrocyte progenitors through a relationship with ferritin and iron. Neurotoxicity Research. 19: 361-73. PMID 20237879 DOI: 10.1007/s12640-010-9167-1  0.389
2011 Hall EC, Lee SY, Mairuae N, Simmons Z, Connor JR. Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues. Neurobiology of Aging. 32: 1409-19. PMID 19775775 DOI: 10.1016/J.Neurobiolaging.2009.08.012  0.617
2011 Mitchell RM, Lee SY, Simmons Z, Connor JR. HFE polymorphisms affect cellular glutamate regulation. Neurobiology of Aging. 32: 1114-23. PMID 19560233 DOI: 10.1016/J.Neurobiolaging.2009.05.016  0.529
2011 Alkhateeb A, Connor J. Abstract 1108: Ferritin binds breast cancer cells and tissue, and promotes proliferation independently of iron content Cancer Research. 71: 1108-1108. DOI: 10.1158/1538-7445.Am2011-1108  0.457
2010 Mairuae N, Hall Ii EC, Cheepsunthorn P, Lee SY, Connor JR. The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure. Journal of Neuroscience Research. 88: 3079-89. PMID 20734416 DOI: 10.1002/Jnr.22466  0.728
2010 Snyder AM, Neely EB, Levi S, Arosio P, Connor JR. Regional and cellular distribution of mitochondrial ferritin in the mouse brain. Journal of Neuroscience Research. 88: 3133-43. PMID 20722075 DOI: 10.1002/Jnr.22462  0.695
2010 Wang J, Eslinger PJ, Doty RL, Zimmerman EK, Grunfeld R, Sun X, Meadowcroft MD, Connor JR, Price JL, Smith MB, Yang QX. Olfactory deficit detected by fMRI in early Alzheimer's disease. Brain Research. 1357: 184-94. PMID 20709038 DOI: 10.1016/J.Brainres.2010.08.018  0.7
2010 Mitchell RM, Simmons Z, Beard JL, Stephens HE, Connor JR. Plasma biomarkers associated with ALS and their relationship to iron homeostasis. Muscle & Nerve. 42: 95-103. PMID 20544912 DOI: 10.1002/Mus.21625  0.564
2010 Alkhateeb AA, Connor JR. Nuclear ferritin: A new role for ferritin in cell biology. Biochimica Et Biophysica Acta. 1800: 793-7. PMID 20347012 DOI: 10.1016/j.bbagen.2010.03.017  0.335
2010 Bartzokis G, Lu PH, Tishler TA, Peters DG, Kosenko A, Barrall KA, Finn JP, Villablanca P, Laub G, Altshuler LL, Geschwind DH, Mintz J, Neely E, Connor JR. Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men. Journal of Alzheimer's Disease : Jad. 20: 333-41. PMID 20164577 DOI: 10.3233/Jad-2010-1368  0.65
2010 Hall EC, Lee SY, Simmons Z, Neely EB, Nandar W, Connor JR. Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D. Biochimica Et Biophysica Acta. 1802: 389-95. PMID 20060900 DOI: 10.1016/J.Bbadis.2010.01.004  0.632
2010 Alkhateeb A, Webb B, Connor J. Abstract 84: The L-ferritin receptor, Scara5, is expressed on breast cancer and glioma cells: A potential functional significance for cancer-associated high serum/CSF levels Cancer Research. 70: 84-84. DOI: 10.1158/1538-7445.Am10-84  0.373
2010 Liu S, Lee S, Slagle-Webb B, Sheehan J, Connor J. Abstract 2622: C282Y HFE polymorphism imparts temozolomide and 17-DMAG resistance via p16INK4A Cancer Research. 70: 2622-2622. DOI: 10.1158/1538-7445.Am10-2622  0.322
2010 Clardy SL, Connor JR. Restless Leg Syndrome Encyclopedia of Neuroscience. 131-135. DOI: 10.1016/B978-008045046-9.00608-2  0.555
2009 Snyder AM, Wang X, Patton SM, Arosio P, Levi S, Earley CJ, Allen RP, Connor JR. Mitochondrial ferritin in the substantia nigra in restless legs syndrome. Journal of Neuropathology and Experimental Neurology. 68: 1193-9. PMID 19816198 DOI: 10.1097/Nen.0B013E3181Bdc44F  0.7
2009 Connor JR, Ghio AJ. The impact of host iron homeostasis on disease. Preface. Biochimica Et Biophysica Acta. 1790: 581-2. PMID 19520233 DOI: 10.1016/j.bbagen.2009.05.004  0.328
2009 Connor JR, Wang XS, Allen RP, Beard JL, Wiesinger JA, Felt BT, Earley CJ. Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome. Brain : a Journal of Neurology. 132: 2403-12. PMID 19467991 DOI: 10.1093/brain/awp125  0.336
2009 Meadowcroft MD, Connor JR, Smith MB, Yang QX. MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice. Journal of Magnetic Resonance Imaging : Jmri. 29: 997-1007. PMID 19388095 DOI: 10.1002/Jmri.21731  0.744
2009 Mitchell RM, Lee SY, Randazzo WT, Simmons Z, Connor JR. Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1. Journal of Neuroinflammation. 6: 6. PMID 19228389 DOI: 10.1186/1742-2094-6-6  0.64
2009 Mitchell RM, Freeman WM, Randazzo WT, Stephens HE, Beard JL, Simmons Z, Connor JR. A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis. Neurology. 72: 14-9. PMID 18987350 DOI: 10.1212/01.Wnl.0000333251.36681.A5  0.501
2009 Todorich B, Pasquini JM, Garcia CI, Paez PM, Connor JR. Oligodendrocytes and myelination: the role of iron. Glia. 57: 467-78. PMID 18837051 DOI: 10.1002/glia.20784  0.4
2009 Snyder AM, Connor JR. Iron, the substantia nigra and related neurological disorders. Biochimica Et Biophysica Acta. 1790: 606-14. PMID 18778755 DOI: 10.1016/J.Bbagen.2008.08.005  0.757
2009 Bartzokis G, Lu PH, Tingus K, Tishler TA, Peters DG, Richard A, Mintz J, Villablanca P, Finn JP, Laub G, Connor JR. IC-P-093: Influence of iron genes and gender on brain iron and cognition Alzheimer's & Dementia. 5: P41-P41. DOI: 10.1016/j.jalz.2009.05.647  0.359
2009 Bartzokis G, Lu PH, Tingus K, Tishler TA, Peters DG, Richard A, Mintz J, Villablanca P, Finn JP, Laub G, Connor JR. P1-121: Influence of iron genes and gender on brain iron and cognition Alzheimer's & Dementia. 5: P211-P211. DOI: 10.1016/J.Jalz.2009.04.126  0.625
2009 Clardy SL, Connor JR, Beard J. The Iron Metabolic System Restless Legs Syndrome. 50-60. DOI: 10.1016/B978-075067518-5.10009-6  0.692
2008 Todorich B, Zhang X, Slagle-Webb B, Seaman WE, Connor JR. Tim-2 is the receptor for H-ferritin on oligodendrocytes. Journal of Neurochemistry. 107: 1495-505. PMID 19014383 DOI: 10.1111/j.1471-4159.2008.05678.x  0.376
2008 Connor JR, Wang XS, Neely EB, Ponnuru P, Morita H, Beard J. Comparative study of the influence of Thy1 deficiency and dietary iron deficiency on dopaminergic profiles in the mouse striatum. Journal of Neuroscience Research. 86: 3194-202. PMID 18615641 DOI: 10.1002/jnr.21758  0.373
2008 Badaracco ME, Ortiz EH, Soto EF, Connor J, Pasquini JM. Effect of transferrin on hypomyelination induced by iron deficiency. Journal of Neuroscience Research. 86: 2663-73. PMID 18459135 DOI: 10.1002/jnr.21709  0.421
2008 Geguchadze RN, Coe CL, Lubach GR, Clardy TW, Beard JL, Connor JR. CSF proteomic analysis reveals persistent iron deficiency-induced alterations in non-human primate infants. Journal of Neurochemistry. 105: 127-36. PMID 17996030 DOI: 10.1111/J.1471-4159.2007.05113.X  0.378
2008 Connor JR, Cheepsunthorn P, Reid J, Radov LA. Iron mediates gene expression in activated microglia Journal of Neurochemistry. 81: 52-53. DOI: 10.1046/j.1471-4159.81.s1.17_3.x  0.77
2008 Connor JR, Thompson K, Ortiz E, Pasquini JM. Manipulation of brain iron status in two mutant mouse models: effects on myelin Journal of Neurochemistry. 81: 49-51. DOI: 10.1046/j.1471-4159.81.s1.16_5.x  0.358
2008 Hall EC, Lee SY, Connor JR. P2-173: Impact of an iron regulatory gene, HFE, on tau phosphorylation mechanisms Alzheimer's & Dementia. 4: T421-T421. DOI: 10.1016/j.jalz.2008.05.1247  0.614
2007 Foglieni B, Ferrari F, Goldwurm S, Santambrogio P, Castiglioni E, Sessa M, Volontè MA, Lalli S, Galli C, Wang XS, Connor J, Sironi F, Canesi M, Biasiotto G, Pezzoli G, et al. Analysis of ferritin genes in Parkinson disease. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 45: 1450-6. PMID 17970701 DOI: 10.1515/CCLM.2007.307  0.332
2007 Kim BH, Jun YC, Jin JK, Kim JI, Kim NH, Leibold EA, Connor JR, Choi EK, Carp RI, Kim YS. Alteration of iron regulatory proteins (IRP1 and IRP2) and ferritin in the brains of scrapie-infected mice. Neuroscience Letters. 422: 158-63. PMID 17614197 DOI: 10.1016/J.Neulet.2007.05.061  0.391
2007 Fisher J, Devraj K, Ingram J, Slagle-Webb B, Madhankumar AB, Liu X, Klinger M, Simpson IA, Connor JR. Ferritin: a novel mechanism for delivery of iron to the brain and other organs. American Journal of Physiology. Cell Physiology. 293: C641-9. PMID 17459943 DOI: 10.1152/Ajpcell.00599.2006  0.499
2007 Meadowcroft MD, Zhang S, Liu W, Park BS, Connor JR, Collins CM, Smith MB, Yang QX. Direct magnetic resonance imaging of histological tissue samples at 3.0T. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 57: 835-41. PMID 17457873 DOI: 10.1002/Mrm.21213  0.701
2007 Ward KL, Tkac I, Jing Y, Felt B, Beard J, Connor J, Schallert T, Georgieff MK, Rao R. Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats. The Journal of Nutrition. 137: 1043-9. PMID 17374674 DOI: 10.1093/Jn/137.4.1043  0.468
2007 Lee SY, Patton SM, Henderson RJ, Connor JR. Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 564-76. PMID 17194693 DOI: 10.1096/Fj.06-6397Com  0.624
2007 House MJ, St Pierre TG, Kowdley KV, Montine T, Connor J, Beard J, Berger J, Siddaiah N, Shankland E, Jin LW. Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from alzheimer's disease patients. Magnetic Resonance in Medicine. 57: 172-80. PMID 17191232 DOI: 10.1002/Mrm.21118  0.472
2006 Clardy SL, Wang X, Zhao W, Liu W, Chase GA, Beard JL, True Felt B, Connor JR. Acute and chronic effects of developmental iron deficiency on mRNA expression patterns in the brain. Journal of Neural Transmission. Supplementum. 173-96. PMID 17447428 DOI: 10.1007/978-3-211-33328-0_19  0.728
2006 Zhang X, Surguladze N, Slagle-Webb B, Cozzi A, Connor JR. Cellular iron status influences the functional relationship between microglia and oligodendrocytes. Glia. 54: 795-804. PMID 16958088 DOI: 10.1002/glia.20416  0.37
2006 Ill AM, Mitchell TR, Neely EB, Connor JR. Metabolic analysis of mouse brains that have compromised iron storage. Metabolic Brain Disease. 21: 77-87. PMID 16855871 DOI: 10.1007/s11011-006-9022-5  0.413
2006 Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutrition Reviews. 64: S34-43; discussion S. PMID 16770951 DOI: 10.1301/Nr.2006.May.S34-S43  0.471
2006 Clardy SL, Wang X, Boyer PJ, Earley CJ, Allen RP, Connor JR. Is ferroportin-hepcidin signaling altered in restless legs syndrome? Journal of the Neurological Sciences. 247: 173-9. PMID 16759669 DOI: 10.1016/J.Jns.2006.04.008  0.717
2006 Felt BT, Beard JL, Schallert T, Shao J, Aldridge JW, Connor JR, Georgieff MK, Lozoff B. Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behavioural Brain Research. 171: 261-70. PMID 16713640 DOI: 10.1016/J.Bbr.2006.04.001  0.361
2006 Beard JL, Felt B, Schallert T, Burhans M, Connor JR, Georgieff MK. Moderate iron deficiency in infancy: biology and behavior in young rats. Behavioural Brain Research. 170: 224-32. PMID 16569441 DOI: 10.1016/J.Bbr.2006.02.024  0.41
2006 Clardy SL, Earley CJ, Allen RP, Beard JL, Connor JR. Ferritin subunits in CSF are decreased in restless legs syndrome. The Journal of Laboratory and Clinical Medicine. 147: 67-73. PMID 16459164 DOI: 10.1016/J.Lab.2005.06.011  0.694
2005 Earley CJ, Connor JR, Beard JL, Clardy SL, Allen RP. Ferritin levels in the cerebrospinal fluid and restless legs syndrome: effects of different clinical phenotypes. Sleep. 28: 1069-75. PMID 16268375 DOI: 10.1093/Sleep/28.9.1069  0.612
2005 Patton SM, Piñero DJ, Surguladze N, Beard J, Connor JR. Subcellular localization of iron regulatory proteins to Golgi and ER membranes. Journal of Cell Science. 118: 4365-73. PMID 16144863 DOI: 10.1242/Jcs.02570  0.37
2005 Zhang X, Haaf M, Todorich B, Grosstephan E, Schieremberg H, Surguladze N, Connor JR. Cytokine toxicity to oligodendrocyte precursors is mediated by iron. Glia. 52: 199-208. PMID 15968631 DOI: 10.1002/Glia.20235  0.36
2005 Henderson RJ, Patton SM, Connor JR. Development of a fluorescent reporter to assess iron regulatory protein activity in living cells. Biochimica Et Biophysica Acta. 1743: 162-8. PMID 15777851 DOI: 10.1016/J.Bbamcr.2004.09.032  0.66
2005 Lee SY, Connor JR. Regulation of Hfe by stress factors in BV-2 cells. Neurobiology of Aging. 26: 803-12. PMID 15718038 DOI: 10.1016/j.neurobiolaging.2004.08.006  0.315
2005 Beard JL, Wiesinger JA, Li N, Connor JR. Brain iron uptake in hypotransferrinemic mice: influence of systemic iron status. Journal of Neuroscience Research. 79: 254-61. PMID 15578731 DOI: 10.1002/jnr.20324  0.383
2005 Huang E, Ong WY, Connor JR. Distribution of divalent metal transporter-1 in the monkey basal ganglia. Neuroscience. 128: 487-96. PMID 15381278 DOI: 10.1016/j.neuroscience.2004.06.055  0.387
2004 Wang XS, Lee S, Simmons Z, Boyer P, Scott K, Liu W, Connor J. Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences. Journal of the Neurological Sciences. 227: 27-33. PMID 15546588 DOI: 10.1016/J.Jns.2004.08.003  0.373
2004 Zecca L, Youdim MB, Riederer P, Connor JR, Crichton RR. Iron, brain ageing and neurodegenerative disorders. Nature Reviews. Neuroscience. 5: 863-73. PMID 15496864 DOI: 10.1038/Nrn1537  0.424
2004 Ortiz E, Pasquini JM, Thompson K, Felt B, Butkus G, Beard J, Connor JR. Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models. Journal of Neuroscience Research. 77: 681-9. PMID 15352214 DOI: 10.1002/jnr.20207  0.372
2004 Wang X, Wiesinger J, Beard J, Felt B, Menzies S, Earley C, Allen R, Connor J. Thy1 expression in the brain is affected by iron and is decreased in Restless Legs Syndrome. Journal of the Neurological Sciences. 220: 59-66. PMID 15140607 DOI: 10.1016/j.jns.2004.02.004  0.527
2004 Knutson M, Menzies S, Connor J, Wessling-Resnick M. Developmental, regional, and cellular expression of SFT/UbcH5A and DMT1 mRNA in brain. Journal of Neuroscience Research. 76: 633-41. PMID 15139022 DOI: 10.1002/Jnr.20113  0.448
2004 Burdo JR, Simpson IA, Menzies S, Beard J, Connor JR. Regulation of the profile of iron-management proteins in brain microvasculature. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 67-74. PMID 14688618 DOI: 10.1097/01.Wcb.0000095800.98378.03  0.812
2004 Henderson RJ, Patton SM, Lee S, Connor JR. P2-125 A mechanism to evaluate the effect of beta-amyloid exposure on intracellular iron Neurobiology of Aging. 25: S260. DOI: 10.1016/S0197-4580(04)80872-8  0.604
2003 Beard JL, Wiesinger JA, Connor JR. Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats. Developmental Neuroscience. 25: 308-15. PMID 14614257 DOI: 10.1159/000073507  0.39
2003 Burdo JR, Antonetti DA, Wolpert EB, Connor JR. Mechanisms and regulation of transferrin and iron transport in a model blood-brain barrier system. Neuroscience. 121: 883-90. PMID 14580938 DOI: 10.1016/S0306-4522(03)00590-6  0.813
2003 Wang XS, Ong WY, Connor JR. Quinacrine attenuates increases in divalent metal transporter-1 and iron levels in the rat hippocampus, after kainate-induced neuronal injury. Neuroscience. 120: 21-9. PMID 12849737 DOI: 10.1016/S0306-4522(03)00293-8  0.36
2003 Beard JL, Connor JR. Iron status and neural functioning. Annual Review of Nutrition. 23: 41-58. PMID 12704220 DOI: 10.1146/annurev.nutr.23.020102.075739  0.409
2003 Siddappa AJ, Rao RB, Wobken JD, Casperson K, Leibold EA, Connor JR, Georgieff MK. Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain. Pediatric Research. 53: 800-7. PMID 12621119 DOI: 10.1203/01.Pdr.0000058922.67035.D5  0.407
2003 Connor JR. Iron transport proteins in the diseased brain. Journal of the Neurological Sciences. 207: 112-3. PMID 12614944 DOI: 10.1016/S0022-510X(02)00436-7  0.352
2003 Han J, Day JR, Connor JR, Beard JL. Gene expression of transferrin and transferrin receptor in brains of control vs. iron-deficient rats. Nutritional Neuroscience. 6: 1-10. PMID 12608731 DOI: 10.1080/1028415021000042811  0.389
2003 Burdo JR, Connor JR. Brain iron uptake and homeostatic mechanisms: an overview. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 63-75. PMID 12572665 DOI: 10.1023/A:1020718718550  0.81
2003 Thompson K, Menzies S, Muckenthaler M, Torti FM, Wood T, Torti SV, Hentze MW, Beard J, Connor J. Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. Journal of Neuroscience Research. 71: 46-63. PMID 12478613 DOI: 10.1002/Jnr.10463  0.495
2002 Han J, Day JR, Connor JR, Beard JL. H and L ferritin subunit mRNA expression differs in brains of control and iron-deficient rats. The Journal of Nutrition. 132: 2769-74. PMID 12221243 DOI: 10.1093/JN/132.9.2769  0.367
2002 Zywicke HA, van Gelderen P, Connor JR, Burdo JR, Garrick MD, Dolan KG, Frank JA, Bulte JW. Microscopic R2* mapping of reduced brain iron in the Belgrade rat. Annals of Neurology. 52: 102-5. PMID 12112055 DOI: 10.1002/Ana.10216  0.8
2002 Siddappa AJ, Rao RB, Wobken JD, Leibold EA, Connor JR, Georgieff MK. Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain. Journal of Neuroscience Research. 68: 761-75. PMID 12111837 DOI: 10.1002/Jnr.10246  0.383
2002 Malecki EA, Cable EE, Isom HC, Connor JR. The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biological Trace Element Research. 86: 73-84. PMID 12002662 DOI: 10.1385/Bter:86:1:73  0.383
2002 Thompson KJ, Fried MG, Ye Z, Boyer P, Connor JR. Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei. Journal of Cell Science. 115: 2165-77. PMID 11973357  0.319
2002 Malecki EA, Connor JR. The case for iron chelation and/or antioxidant therapy in Alzheimer's disease Drug Development Research. 56: 526-530. DOI: 10.1002/DDR.10105  0.305
2001 Connor JR, Milward EA, Moalem S, Sampietro M, Boyer P, Percy ME, Vergani C, Scott RJ, Chorney M. Is hemochromatosis a risk factor for Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 3: 471-477. PMID 12214033 DOI: 10.3233/Jad-2001-3506  0.506
2001 Burdo JR, Menzies SL, Simpson IA, Garrick LM, Garrick MD, Dolan KG, Haile DJ, Beard JL, Connor JR. Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat. Journal of Neuroscience Research. 66: 1198-207. PMID 11746453 DOI: 10.1002/Jnr.1256  0.794
2001 Piñero DJ, Li N, Hu J, Beard JL, Connor JR. The intracellular location of iron regulatory proteins is altered as a function of iron status in cell cultures and rat brain. The Journal of Nutrition. 131: 2831-6. PMID 11694604 DOI: 10.1093/Jn/131.11.2831  0.38
2001 Connor JR, Menzies SL, Burdo JR, Boyer PJ. Iron and iron management proteins in neurobiology. Pediatric Neurology. 25: 118-29. PMID 11551742 DOI: 10.1016/S0887-8994(01)00303-4  0.814
2001 Takeda A, Takatsuka K, Connor JR, Oku N. Abnormal iron accumulation in the brain of neonatal hypotransferrinemic mice. Brain Research. 912: 154-61. PMID 11532431 DOI: 10.1016/S0006-8993(01)02719-6  0.35
2001 Thompson KJ, Shoham S, Connor JR. Iron and neurodegenerative disorders. Brain Research Bulletin. 55: 155-64. PMID 11470311 DOI: 10.1016/S0361-9230(01)00510-X  0.419
2001 Cheepsunthorn P, Radov L, Menzies S, Reid J, Connor JR. Characterization of a novel brain-derived microglial cell line isolated from neonatal rat brain. Glia. 35: 53-62. PMID 11424192 DOI: 10.1002/Glia.1070  0.753
2001 Cheepsunthorn P, Palmer C, Menzies S, Roberts RL, Connor JR. Hypoxic/ischemic insult alters ferritin expression and myelination in neonatal rat brains. The Journal of Comparative Neurology. 431: 382-96. PMID 11223809 DOI: 10.1002/1096-9861(20010319)431:4<382::AID-CNE1077>3.0.CO;2-#  0.754
2000 Earley CJ, Allen RP, Beard JL, Connor JR. Insight into the pathophysiology of restless legs syndrome. Journal of Neuroscience Research. 62: 623-8. PMID 11104500 DOI: 10.1002/1097-4547(20001201)62:5<623::AID-JNR1>3.0.CO;2-H  0.397
2000 Georgieff MK, Wobken JK, Welle J, Burdo JR, Connor JR. Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta. Placenta. 21: 799-804. PMID 11095929 DOI: 10.1053/Plac.2000.0566  0.765
2000 Piñero DJ, Hu J, Cook BM, Scaduto RC, Connor JR. Interleukin-1beta increases binding of the iron regulatory protein and the synthesis of ferritin by increasing the labile iron pool. Biochimica Et Biophysica Acta. 1497: 279-88. PMID 10996652 DOI: 10.1016/S0167-4889(00)00066-5  0.375
2000 Hulet SW, Heyliger SO, Powers S, Connor JR. Oligodendrocyte progenitor cells internalize ferritin via clathrin-dependent receptor mediated endocytosis. Journal of Neuroscience Research. 61: 52-60. PMID 10861799 DOI: 10.1002/1097-4547(20000701)61:1<52::AID-JNR6>3.0.CO;2-T  0.346
2000 Ye Z, Connor JR. Identification of iron responsive genes by screening cDNA libraries from suppression subtractive hybridization with antisense probes from three iron conditions. Nucleic Acids Research. 28: 1802-7. PMID 10734200 DOI: 10.1093/NAR/28.8.1802  0.35
2000 Piñero DJ, Li NQ, Connor JR, Beard JL. Variations in dietary iron alter brain iron metabolism in developing rats. The Journal of Nutrition. 130: 254-63. PMID 10720179 DOI: 10.1093/JN/130.2.254  0.416
2000 Malecki EA, Buhl KM, Beard JL, Jacobs CR, Connor JR, Donahue HJ. Bone structural and mechanical properties are affected by hypotransferrinemia but not by iron deficiency in mice Journal of Bone and Mineral Research. 15: 271-277. PMID 10703928 DOI: 10.1359/Jbmr.2000.15.2.271  0.303
2000 Piñero DJ, Connor JR. Iron in the Brain: An Important Contributor in Normal and Diseased States The Neuroscientist. 6: 435-453. DOI: 10.1177/107385840000600607  0.42
1999 Malecki EA, Devenyi AG, Beard JL, Connor JR. Existing and emerging mechanisms for transport of iron and manganese to the brain. Journal of Neuroscience Research. 56: 113-22. PMID 10777372 DOI: 10.1002/(SICI)1097-4547(19990415)56:2<113::AID-JNR1>3.0.CO;2-K  0.302
1999 Ye Z, Connor JR. Screening of transcriptionally regulated genes following iron chelation in human astrocytoma cells. Biochemical and Biophysical Research Communications. 264: 709-13. PMID 10543996 DOI: 10.1006/BBRC.1999.1554  0.38
1999 Burdo JR, Martin J, Menzies SL, Dolan KG, Romano MA, Fletcher RJ, Garrick MD, Garrick LM, Connor JR. Cellular distribution of iron in the brain of the Belgrade rat. Neuroscience. 93: 1189-96. PMID 10473284 DOI: 10.1016/S0306-4522(99)00207-9  0.811
1999 Palmer C, Menzies SL, Roberts RL, Pavlick G, Connor JR. Changes in iron histochemistry after hypoxic-ischemic brain injury in the neonatal rat. Journal of Neuroscience Research. 56: 60-71. PMID 10213476 DOI: 10.1002/(SICI)1097-4547(19990401)56:1<60::AID-JNR8>3.0.CO;2-A  0.398
1999 Hulet SW, Hess EJ, Debinski W, Arosio P, Bruce K, Powers S, Connor JR. Characterization and distribution of ferritin binding sites in the adult mouse brain Journal of Neurochemistry. 72: 868-874. PMID 9930764 DOI: 10.1046/J.1471-4159.1999.720868.X  0.329
1998 Malecki EA, Devenyi AG, Beard JL, Connor JR. Transferrin response in normal and iron-deficient mice heterozygotic for hypotransferrinemia; effects on iron and manganese accumulation. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 11: 265-76. PMID 9850571 DOI: 10.1023/A:1009280922387  0.383
1998 Cheepsunthorn P, Palmer C, Connor JR. Cellular distribution of ferritin subunits in postnatal rat brain. The Journal of Comparative Neurology. 400: 73-86. PMID 9762867 DOI: 10.1002/(Sici)1096-9861(19981012)400:1<73::Aid-Cne5>3.0.Co;2-Q  0.79
1998 Takeda A, Devenyi A, Connor JR. Evidence for non-transferrin-mediated uptake and release of iron and manganese in glial cell cultures from hypotransferrinemic mice. Journal of Neuroscience Research. 51: 454-62. PMID 9514199 DOI: 10.1002/(SICI)1097-4547(19980215)51:4<454::AID-JNR5>3.0.CO;2-B  0.362
1998 Erikson KM, Beard JL, Connor JR. Distribution of brain iron, ferritin, and transferrin in the 28-day-old piglet Journal of Nutritional Biochemistry. 9: 276-284. DOI: 10.1016/S0955-2863(98)00021-7  0.411
1997 Erikson KM, Pinero DJ, Connor JR, Beard JL. Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats. The Journal of Nutrition. 127: 2030-8. PMID 9311961 DOI: 10.1093/Jn/127.10.2030  0.406
1997 Focht SJ, Snyder BS, Beard JL, Van Gelder W, Williams LR, Connor JR. Regional distribution of iron, transferrin, ferritin, and oxidatively- modified proteins in young and aged Fischer 344 rat brains Neuroscience. 79: 255-261. PMID 9178881 DOI: 10.1016/S0306-4522(96)00607-0  0.384
1997 Blissman G, Menzies S, Beard J, Palmer C, Connor J. The expression of ferritin subunits and iron in oligodendrocytes in neonatal porcine brains. Developmental Neuroscience. 18: 274-81. PMID 8911767 DOI: 10.1159/000111417  0.466
1997 CONNOR JR, BEARD JL. Dietary Iron Supplements in the Elderly Nutrition Today. 32: 102-109. DOI: 10.1097/00017285-199705000-00002  0.34
1996 Connor JR, Menzies SL. Cellular management of iron in the brain. Journal of the Neurological Sciences. 33-44. PMID 8847543 DOI: 10.1016/0022-510X(95)00206-H  0.44
1996 Dickinson TK, Devenyi AG, Connor JR. Distribution of injected iron 59 and manganese 54 in hypotransferrinemic mice. The Journal of Laboratory and Clinical Medicine. 128: 270-8. PMID 8783634 DOI: 10.1016/S0022-2143(96)90028-1  0.322
1996 Connor JR, Menzies SL. Relationship of iron to oligodendrocytes and myelination. Glia. 17: 83-93. PMID 8776576 DOI: 10.1002/(SICI)1098-1136(199606)17:2<83::AID-GLIA1>3.0.CO;2-7  0.412
1995 Miller MW, Roskams AJ, Connor JR. Iron regulation in the developing rat brain: effect of in utero ethanol exposure. Journal of Neurochemistry. 65: 373-80. PMID 7790882  0.445
1995 Chen Q, Connor JR, Beard JL. Brain iron, transferrin and ferritin concentrations are altered in developing iron-deficient rats. The Journal of Nutrition. 125: 1529-35. PMID 7782907 DOI: 10.1093/JN/125.6.1529  0.411
1995 Dickinson TK, Connor JR. Cellular distribution of iron, transferrin, and ferritin in the hypotransferrinemic (Hp) mouse brain. The Journal of Comparative Neurology. 355: 67-80. PMID 7636015 DOI: 10.1002/CNE.903550109  0.425
1995 Loeffler DA, Connor JR, Juneau PL, Snyder BS, Kanaley L, DeMaggio AJ, Nguyen H, Brickman CM, LeWitt PA. Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions Journal of Neurochemistry. 65: 710-716. PMID 7616227 DOI: 10.1046/j.1471-4159.1995.65020710.x  0.381
1994 Roskams AJ, Connor JR. Iron, transferrin, and ferritin in the rat brain during development and aging. Journal of Neurochemistry. 63: 709-16. PMID 8035195  0.406
1994 Beard JL, Chen Q, Connor J, Jones BC. Altered monamine metabolism in caudate-putamen of iron-deficient rats Pharmacology, Biochemistry and Behavior. 48: 621-624. PMID 7524105 DOI: 10.1016/0091-3057(94)90323-9  0.45
1993 Beard JL, Connor JR, Jones BC. Iron in the brain Nutrition Reviews. 51: 157-170. PMID 8371846 DOI: 10.1111/J.1753-4887.1993.TB03096.X  0.398
1992 Roskams AJ, Connor JR. Transferrin receptor expression in myelin deficient (md) rats. Journal of Neuroscience Research. 31: 421-7. PMID 1640494 DOI: 10.1002/jnr.490310304  0.342
1990 Connor JR, Menzies SL. Altered cellular distribution of iron in the central nervous system of myelin deficient rats. Neuroscience. 34: 265-71. PMID 2325851 DOI: 10.1016/0306-4522(90)90320-4  0.397
1990 Roskams AJ, Connor JR. Aluminum access to the brain: a role for transferrin and its receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 9024-7. PMID 2247478  0.327
1986 Connor JR, Fine RE. The distribution of transferrin immunoreactivity in the rat central nervous system Brain Research. 368: 319-328. PMID 3697729 DOI: 10.1016/0006-8993(86)90576-7  0.35
1984 Connor JR, Peters A. Vasoactive intestinal polypeptide-immunoreactive neurons in rat visual cortex. Neuroscience. 12: 1027-44. PMID 6384816 DOI: 10.1016/0306-4522(84)90002-2  0.457
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