☰

Ryan A. Altman - Publications

Affiliations: 
2011-2020 Medicinal Chemistry University of Kansas, Lawrence, KS, United States 
 2020- Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
 2020- Chemistry Purdue University, West Lafayette, IN, United States 
Area:
decarboxylative strategies for fluoroalkylation, and the use of fluorinated peptidomimetics to perturb physicochemical and biophysical properties of neuropeptides
Website:
https://www.mcmp.purdue.edu/faculty/raaltman
Tree Info Similar researchers PubMed Report error

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Intelli AJ, Pal M, Selvaraju M, Altman RA. Palladium-Catalyzed Dearomatization of Benzothiophenes: Isolation and Functionalization of a Discrete Dearomatized Intermediate. Synthesis. 55: 3568-3574. PMID 37915377 DOI: 10.1055/a-2092-9012  0.812
2023 Intelli AJ, Lee RT, Altman RA. Peroxide-Initiated Hydrophosphinylation of -Difluoroalkenes. The Journal of Organic Chemistry. PMID 37738112 DOI: 10.1021/acs.joc.3c01562  0.821
2023 Herrick RM, Abd El-Gaber MK, Coy G, Altman RA. A diselenide additive enables photocatalytic hydroalkoxylation of -difluoroalkenes. Chemical Communications (Cambridge, England). PMID 37082905 DOI: 10.1039/d3cc01012k  0.439
2022 Sorrentino JP, Herrick RM, Abd El-Gaber MK, Abdelazem AZ, Kumar A, Altman RA. General Co-catalytic Hydrothiolation of -Difluoroalkenes. The Journal of Organic Chemistry. PMID 36469658 DOI: 10.1021/acs.joc.2c02343  0.841
2022 Koley S, Cayton KT, González-Montiel GA, Yadav MR, Orsi DL, Intelli AJ, Cheong PH, Altman RA. Cu(II)-Catalyzed Unsymmetrical Dioxidation of -Difluoroalkenes to Generate α,α-Difluorinated-α-phenoxyketones. The Journal of Organic Chemistry. 87: 10710-10725. PMID 35914193 DOI: 10.1021/acs.joc.2c00925  0.784
2022 Sorrentino JP, Altman RA. Fluoroalkylation of Dextromethorphan Improves CNS Exposure and Metabolic Stability. Acs Medicinal Chemistry Letters. 13: 707-713. PMID 35450379 DOI: 10.1021/acsmedchemlett.2c00055  0.767
2021 Sorrentino JP, Altman RA. Fluorine-Retentive Strategies for the Functionalization of -Difluoroalkenes. Synthesis. 53: 3935-3950. PMID 34707322 DOI: 10.1055/a-1547-9270  0.818
2021 Sorrentino JP, Orsi DL, Altman RA. Correction to "Acid-Catalyzed Hydrothiolation of -Difluorostyrenes to Access α,α-Difluoroalkylthioethers". The Journal of Organic Chemistry. PMID 33621093 DOI: 10.1021/acs.joc.1c00395  0.788
2021 Sorrentino JP, Orsi DL, Altman RA. Acid-Catalyzed Hydrothiolation of -Difluorostyrenes to Access α,α-Difluoroalkylthioethers. The Journal of Organic Chemistry. 86: 2297-2311. PMID 33471529 DOI: 10.1021/acs.joc.0c02440  0.811
2020 Yuan K, Feoktistova T, Cheong PH, Altman RA. Arylation of -difluoroalkenes using a Pd/Cu Co-catalytic system that avoids β-fluoride elimination. Chemical Science. 12: 1363-1367. PMID 34163899 DOI: 10.1039/d0sc05192f  0.375
2020 Yang Y, Borel T, de Azambuja F, Johnson D, Sorrentino JP, Udokwu C, Davis I, Liu A, Altman RA. Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. Journal of Medicinal Chemistry. PMID 33369426 DOI: 10.1021/acs.jmedchem.0c01762  0.785
2020 Orsi DL, Douglas JT, Sorrentino JP, Altman RA. Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of -Difluoroalkenes. The Journal of Organic Chemistry. PMID 32697905 DOI: 10.1021/Acs.Joc.0C00415  0.819
2020 Koley S, Altman RA. Recent Advances in Transition Metal-Catalyzed Functionalization of -Difluoroalkenes. Israel Journal of Chemistry. 60: 313-339. PMID 32523163 DOI: 10.1002/Ijch.201900173  0.47
2020 Sorrentino JP, Ambler BR, Altman RA. Late-Stage Conversion of a Metabolically Labile Aryl Methyl Ether-Containing Natural Product to Fluoroalkyl Analogs. The Journal of Organic Chemistry. PMID 32191836 DOI: 10.1021/Acs.Joc.0C00125  0.8
2020 de Azambuja F, Yang MH, Feoktistova T, Selvaraju M, Brueckner AC, Grove MA, Koley S, Cheong PH, Altman RA. Connecting remote C-H bond functionalization and decarboxylative coupling using simple amines. Nature Chemistry. PMID 32152476 DOI: 10.1038/S41557-020-0428-1  0.724
2019 Orsi DL, Yadav MR, Altman RA. Organocatalytic Strategy for Hydrophenolation of -Difluoroalkenes. Tetrahedron. 75: 4325-4336. PMID 32103843 DOI: 10.1016/J.Tet.2019.04.016  0.831
2019 Vallakati R, Plotnikov AT, Altman RA. Synthesis of 2-D--Tryptophan by Sequential Ir-Catalyzed Reactions. Tetrahedron. 75: 2261-2264. PMID 31130755 DOI: 10.1016/J.Tet.2019.02.054  0.369
2019 Eeda V, Selvaraju M, Altman RA. Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluoromethylalkenes as Amide Isopolar Mimics. Journal of Fluorine Chemistry. 218: 90-98. PMID 31061541 DOI: 10.1016/J.Jfluchem.2018.12.005  0.364
2019 de Azambuja F, Lovrien SM, Ross P, Ambler BR, Altman RA. Catalytic One-Step Deoxytrifluoromethylation of Alcohols. The Journal of Organic Chemistry. PMID 30632749 DOI: 10.1021/Acs.Joc.8B03072  0.813
2019 Han C, Alabanza LM, Kelly SM, Orsi DL, Gosselin F, Altman RA. BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale Organic Process Research & Development. 23: 1695-1702. DOI: 10.1021/Acs.Oprd.9B00201  0.799
2018 Shin I, Ambler BR, Wherritt D, Griffith WP, Maldonado AC, Altman RA, Liu A. Stepwise O-Atom Transfer in Heme-based Tryptophan Dioxygenase: The Role of Substrate Ammonium in the Epoxide Ring Opening. Journal of the American Chemical Society. PMID 29506384 DOI: 10.1021/Jacs.8B00262  0.807
2017 Orsi DL, Altman RA. Exploiting the unusual effects of fluorine in methodology. Chemical Communications (Cambridge, England). PMID 28503693 DOI: 10.1039/C7Cc02341C  0.815
2017 Orsi DL, Easley BJ, Lick AM, Altman RA. Base Catalysis Enables Access to α,α-Difluoroalkylthioethers. Organic Letters. PMID 28332397 DOI: 10.1021/Acs.Orglett.7B00386  0.816
2016 Ambler BR, Yang MH, Altman RA. Metal-catalyzed Decarboxylative Fluoroalkylation Reactions. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 27: 2747-2755. PMID 28260839 DOI: 10.1055/S-0036-1588637  0.82
2016 Yang MH, Hunt JR, Sharifi N, Altman RA. Palladium Catalysis Enables Benzylation of α,α-Difluoroketone Enolates. Angewandte Chemie (International Ed. in English). PMID 27312868 DOI: 10.1002/Anie.201604149  0.805
2015 Ambler BR, Zhu L, Altman RA. Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates. The Journal of Organic Chemistry. PMID 26225803 DOI: 10.1021/Acs.Joc.5B01343  0.798
2015 Ambler BR, Peddi S, Altman RA. Ligand-Controlled Regioselective Copper-Catalyzed Trifluoromethylation To Generate (Trifluoromethyl)allenes. Organic Letters. 17: 2506-9. PMID 25910053 DOI: 10.1021/Acs.Orglett.5B01027  0.804
2015 Yang MH, Orsi DL, Altman RA. Ligand-controlled regiodivergent palladium-catalyzed decarboxylative allylation reaction to access α,α-difluoroketones. Angewandte Chemie (International Ed. in English). 54: 2361-5. PMID 25581845 DOI: 10.1002/ange.201410039  0.821
2014 Ambler BR, Peddi S, Altman RA. Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates. Synthesis. 46: 1938-1946. PMID 25294948 DOI: 10.1055/S-0033-1339128  0.797
2014 Qiao Y, Si T, Yang MH, Altman RA. Metal-free trifluoromethylation of aromatic and heteroaromatic aldehydes and ketones. The Journal of Organic Chemistry. 79: 7122-31. PMID 25001876 DOI: 10.1021/Jo501289V  0.812
2014 Qiao Y, Zhu L, Ambler BR, Altman RA. Decarboxylative fluorination strategies for accessing medicinally- relevant products. Current Topics in Medicinal Chemistry. 14: 966-78. PMID 24484421 DOI: 10.2174/1568026614666140202210850  0.797
2013 Ambler BR, Altman RA. Copper-catalyzed decarboxylative trifluoromethylation of allylic bromodifluoroacetates. Organic Letters. 15: 5578-81. PMID 24117395 DOI: 10.1021/Ol402780K  0.82
2013 Zhu L, Liu S, Douglas JT, Altman RA. Copper-mediated deoxygenative trifluoromethylation of benzylic xanthates: generation of a C-CF(3) bond from an O-based electrophile. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 12800-5. PMID 23922222 DOI: 10.1002/Chem.201302328  0.797
2013 Yang MH, Matikonda SS, Altman RA. Preparation of fluoroalkenes via the Shapiro reaction: direct access to fluorinated peptidomimetics. Organic Letters. 15: 3894-7. PMID 23879432 DOI: 10.1021/Ol401637N  0.76
2010 Altman RA, Nilsson BL, Overman LE, Read de Alaniz J, Rohde JM, Taupin V. Total synthesis of (+)-nankakurines A and B and (±)-5-epi-nankakurine A. The Journal of Organic Chemistry. 75: 7519-34. PMID 20958075 DOI: 10.1021/Jo101619D  0.713
2009 Taylor AM, Altman RA, Buchwald SL. Palladium-catalyzed enantioselective alpha-arylation and alpha-vinylation of oxindoles facilitated by an axially chiral P-stereogenic ligand. Journal of the American Chemical Society. 131: 9900-1. PMID 19580273 DOI: 10.1021/Ja903880Q  0.477
2008 Altman RA, Hyde AM, Huang X, Buchwald SL. Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles. Journal of the American Chemical Society. 130: 9613-20. PMID 18588302 DOI: 10.1021/Ja803179S  0.78
2008 Altman RA, Anderson KW, Buchwald SL. Pyrrole-2-carboxylic acid as a ligand for the Cu-catalyzed reactions of primary anilines with aryl halides. The Journal of Organic Chemistry. 73: 5167-9. PMID 18543973 DOI: 10.1021/Jo8008676  0.694
2008 Altman RA, Shafir A, Choi A, Lichtor PA, Buchwald SL. An improved Cu-based catalyst system for the reactions of alcohols with aryl halides. The Journal of Organic Chemistry. 73: 284-6. PMID 18044928 DOI: 10.1021/Jo702024P  0.567
2007 Altman RA, Buchwald SL. Pd-catalyzed Suzuki-Miyaura reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 3115-21. PMID 18079711 DOI: 10.1038/Nprot.2007.411  0.606
2007 Altman RA, Fors BP, Buchwald SL. Pd-catalyzed amination reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 2881-7. PMID 18007623 DOI: 10.1038/Nprot.2007.414  0.745
2007 Altman RA, Buchwald SL. Cu-catalyzed Goldberg and Ullmann reactions of aryl halides using chelating N- and O-based ligands. Nature Protocols. 2: 2474-9. PMID 17947989 DOI: 10.1038/Nprot.2007.364  0.617
2007 Altman RA, Koval ED, Buchwald SL. Copper-catalyzed N-arylation of imidazoles and benzimidazoles. The Journal of Organic Chemistry. 72: 6190-9. PMID 17625886 DOI: 10.1021/Jo070807A  0.59
2007 Altman RA, Buchwald SL. Cu-catalyzed N- and O-arylation of 2-, 3-, and 4-hydroxypyridines and hydroxyquinolines. Organic Letters. 9: 643-6. PMID 17286371 DOI: 10.1021/Ol062904G  0.554
2006 Anderson KW, Tundel RE, Ikawa T, Altman RA, Buchwald SL. Monodentate phosphines provide highly active catalysts for Pd-catalyzed C-N bond-forming reactions of heteroaromatic halides/amines and (H)N-heterocycles. Angewandte Chemie (International Ed. in English). 45: 6523-7. PMID 16955526 DOI: 10.1002/Anie.200601612  0.665
2006 Altman RA, Buchwald SL. 4,7-Dimethoxy-1,10-phenanthroline: an excellent ligand for the Cu-catalyzed N-arylation of imidazoles. Organic Letters. 8: 2779-82. PMID 16774255 DOI: 10.1021/Ol0608505  0.575
Show low-probability matches.