☰

Li Gan - Publications

Affiliations: 
Gladstone Institute/UCSF, San Francisco, CA, United States 
 University of California, San Francisco, San Francisco, CA 
Area:
Cellular and Molecular Pathways in Neurodegeneration
Tree Info Grants Similar researchers PubMed Report error

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Luo W, Chen H, Fan L, Guo Q, Wong MY, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Mok SA, ... ... Gan L, et al. DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. Research Square. PMID 37961627 DOI: 10.21203/rs.3.rs-3454358/v1  0.304
2023 Chen H, Fan L, Guo Q, Wong MY, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Patel T, Mok SA, ... ... Gan L, et al. DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. Biorxiv : the Preprint Server For Biology. PMID 37961594 DOI: 10.1101/2023.10.26.563970  0.304
2023 Lopez-Lee C, Kodama L, Fan L, Wong MY, Foxe NR, Jiaz L, Yu F, Ye P, Zhu J, Norman K, Torres ER, Kim RD, Mousa GA, Dubal D, Liddelow S, ... ... Gan L, et al. Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging. Biorxiv : the Preprint Server For Biology. PMID 37781600 DOI: 10.1101/2023.09.19.558439  0.726
2023 Das M, Mao W, Voskobiynyk Y, Necula D, Lew I, Petersen C, Zahn A, Yu GQ, Yu X, Smith N, Sayed F, Gan L, Paz JT, Mucke L. Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models. Neurobiology of Disease. 106263. PMID 37591465 DOI: 10.1016/j.nbd.2023.106263  0.551
2020 Limbad C, Oron TR, Alimirah F, Davalos AR, Tracy TE, Gan L, Desprez PY, Campisi J. Astrocyte senescence promotes glutamate toxicity in cortical neurons. Plos One. 15: e0227887. PMID 31945125 DOI: 10.1371/Journal.Pone.0227887  0.406
2020 Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Molecular Neurodegeneration. 15: 2. PMID 31906970 DOI: 10.1186/S13024-019-0354-0  0.36
2019 Tracy T, Claiborn KC, Gan L. Regulation of Tau Homeostasis and Toxicity by Acetylation. Advances in Experimental Medicine and Biology. 1184: 47-55. PMID 32096027 DOI: 10.1007/978-981-32-9358-8_4  0.404
2019 Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC, Clelland CD, Cheng Z, Yu G, Li Q, Kosik KS, ... Gan L, et al. Microglial microRNAs mediate sex-specific responses to tau pathology. Nature Neuroscience. PMID 31873194 DOI: 10.1038/S41593-019-0560-7  0.351
2019 Lin LC, Nana AL, Hepker M, Hwang JL, Gaus SE, Spina S, Cosme CG, Gan L, Grinberg LT, Geschwind DH, Coppola G, Rosen HJ, Miller BL, Seeley WW. Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants. Acta Neuropathologica Communications. 7: 159. PMID 31640778 DOI: 10.1186/S40478-019-0809-0  0.366
2019 Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, ... ... Gan L, et al. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. PMID 31631020 DOI: 10.1016/J.Stemcr.2019.09.006  0.33
2019 Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, ... ... Gan L, et al. Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron. PMID 31542321 DOI: 10.1016/J.Neuron.2019.08.008  0.34
2019 Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, ... ... Gan L, et al. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nature Genetics. 51: 1252-1262. PMID 31367015 DOI: 10.1038/S41588-019-0472-1  0.317
2019 Kodama L, Gan L. Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases? Trends in Molecular Medicine. PMID 31171460 DOI: 10.1016/j.molmed.2019.05.001  0.342
2019 Mucke L, Akassoglou K, Das M, Gan L, Ho K, Merlini M, Orr A, Rafalski VA, Ryu JK, Sayed F, Seeley WW, Yu G. ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P188. DOI: 10.1016/J.Jalz.2019.06.4393  0.539
2019 Theofilas P, Hayath M, Wang C, Butler D, McAllen S, Arkin M, Gestwicki J, Cuervo AM, Kayed R, Karch CM, Temple S, Gan L, Grinberg LT. P3-200: Tau-Mediated Cell Death Mechanisms In Mapt V337M Ipsc-Derived Human Neurons Alzheimers & Dementia. 15: 1006. DOI: 10.1016/J.Jalz.2019.06.3229  0.326
2018 Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, et al. Military-related risk factors for dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30415806 DOI: 10.1016/J.Jalz.2018.08.011  0.325
2018 Gan L, Cookson MR, Petrucelli L, La Spada AR. Converging pathways in neurodegeneration, from genetics to mechanisms. Nature Neuroscience. 21: 1300-1309. PMID 30258237 DOI: 10.1038/S41593-018-0237-7  0.318
2018 Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, ... Gan L, et al. Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232263 DOI: 10.1073/Pnas.1811411115  0.418
2018 Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, ... ... Gan L, et al. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 174: 505-520. PMID 30053424 DOI: 10.1016/J.Cell.2018.06.016  0.516
2018 Tracy TE, Gan L. Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease. Current Opinion in Neurobiology. 51: 134-138. PMID 29753269 DOI: 10.1016/J.Conb.2018.04.027  0.387
2018 Martinez-Losa M, Tracy TE, Ma K, Verret L, Clemente-Perez A, Khan AS, Cobos I, Ho K, Gan L, Mucke L, Alvarez-Dolado M, Palop JJ. Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease. Neuron. PMID 29551491 DOI: 10.1016/J.Neuron.2018.02.029  0.728
2018 Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L. SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29540553 DOI: 10.1523/Jneurosci.2369-17.2018  0.388
2018 Udeochu J, Sayed FA, Gan L. TREM2 and Amyloid Beta: A Love-Hate Relationship. Neuron. 97: 991-993. PMID 29518360 DOI: 10.1016/J.Neuron.2018.02.018  0.335
2018 Ehrenberg AJ, Petersen C, Morales DO, Theofilas P, Hepker M, Li AN, Cosme CG, Suemoto CK, Alho AT, Leite REP, Rodriguez RD, Farfel JM, Ferretti-Rebustini REdL, Nascimento CF, Nitrini R, ... ... Gan L, et al. P1-237: Post-Translational Modifications Of Tau In Alzheimer'S Disease: A Postmortem Study In Humans Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.242  0.375
2017 Krencik R, Seo K, van Asperen JV, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME, Gan L, Horner PJ, Rowitch DH, Ullian EM. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 9: 1745-1753. PMID 29198827 DOI: 10.1016/J.Stemcr.2017.10.026  0.307
2017 Wang C, Telpoukhovskaia MA, Bahr BA, Chen X, Gan L. Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases. Current Opinion in Neurobiology. 48: 52-58. PMID 29028540 DOI: 10.1016/j.conb.2017.09.005  0.384
2017 Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. The Journal of Biological Chemistry. PMID 28972160 DOI: 10.1074/Jbc.M117.815126  0.351
2017 Wang C, Ward ME, Chen R, Liu K, Tracy TE, Chen X, Xie M, Sohn PD, Ludwig C, Meyer-Franke A, Karch CM, Ding S, Gan L. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports. PMID 28966121 DOI: 10.1016/J.Stemcr.2017.08.019  0.33
2017 Krabbe G, Minami SS, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC, Sayed F, Merlini M, Ward ME, Perry DC, Lee SE, ... ... Gan L, et al. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28438992 DOI: 10.1073/Pnas.1700477114  0.347
2017 Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, ... ... Gan L, et al. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Science Translational Medicine. 9. PMID 28404863 DOI: 10.1126/Scitranslmed.Aah5642  0.312
2017 Tracy TE, Gan L. Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28083916 DOI: 10.1002/Bies.201600224  0.376
2016 Wes PD, Sayed FA, Bard F, Gan L. Targeting microglia for the treatment of Alzheimer's Disease. Glia. PMID 27100611 DOI: 10.1002/Glia.22988  0.407
2016 Tracy TE, Sohn PD, Minami SS, Wang C, Min SW, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R, Cong X, Schilling B, Ellerby LM, Huganir RL, Gan L. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss. Neuron. PMID 27041503 DOI: 10.1016/J.Neuron.2016.03.005  0.378
2015 Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, ... ... Gan L, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature Medicine. PMID 26390242 DOI: 10.1038/Nm.3951  0.416
2015 Gan L. Inge grundke-iqbal award for Alzheimer’s research: Progranulin protects against amyloid b deposition and toxicity in Alzheimer's disease mouse models Alzheimers & Dementia. 11: 216. DOI: 10.1016/J.Jalz.2015.07.235  0.38
2014 Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV, Gan L. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nature Medicine. 20: 1157-64. PMID 25261995 DOI: 10.1038/nm.3672  0.613
2014 Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, ... ... Gan L, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/Jem.20140214  0.357
2013 Min SW, Sohn PD, Cho SH, Swanson RA, Gan L. Sirtuins in neurodegenerative diseases: an update on potential mechanisms. Frontiers in Aging Neuroscience. 5: 53. PMID 24093018 DOI: 10.3389/Fnagi.2013.00053  0.346
2013 Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation. Acta Neuropathologica. 125: 581-93. PMID 23371364 DOI: 10.1007/S00401-013-1080-2  0.349
2012 Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113  0.322
2012 Wang C, Sun B, Zhou Y, Grubb A, Gan L. Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein. The Journal of Biological Chemistry. 287: 39834-41. PMID 23024364 DOI: 10.1074/jbc.M112.371641  0.395
2012 Pappas DJ, Gabatto PA, Oksenberg D, Khankhanian P, Baranzini SE, Gan L, Oksenberg JR. Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules. Neuroscience. 226: 10-20. PMID 22986168 DOI: 10.1016/j.neuroscience.2012.09.007  0.317
2012 Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots. Journal of Neuroinflammation. 9: 22. PMID 22272874 DOI: 10.1186/1742-2094-9-22  0.532
2011 Kauppinen TM, Suh SW, Higashi Y, Berman AE, Escartin C, Won SJ, Wang C, Cho SH, Gan L, Swanson RA. Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β. Journal of Neuroinflammation. 8: 152. PMID 22051244 DOI: 10.1186/1742-2094-8-152  0.386
2011 Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J. Protective effects and mechanisms of sirtuins in the nervous system. Progress in Neurobiology. 95: 373-95. PMID 21930182 DOI: 10.1016/j.pneurobio.2011.09.001  0.346
2011 Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM, Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. The Journal of Biological Chemistry. 286: 32713-22. PMID 21771791 DOI: 10.1074/Jbc.M111.254268  0.437
2011 Sun B, Gan L. Manipulation of gene expression in the central nervous system with lentiviral vectors. Methods in Molecular Biology (Clifton, N.J.). 670: 155-68. PMID 20967590 DOI: 10.1007/978-1-60761-744-0_12  0.347
2011 Gan L, Min S, Cho S, Zhou Y, Haroutunian V, Seeley B, Huang E, Shen Y, Masliah E, Cole P, Ott M. Acetylation of tau contributes to tau accumulation and dysfunction Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1989  0.312
2010 Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron. 67: 953-66. PMID 20869593 DOI: 10.1016/J.Neuron.2010.08.044  0.37
2010 Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Erratum to Acetylation of tau inhibits its degradation and contributes to tauopathy Neuron. 68. DOI: 10.1016/J.Neuron.2010.11.013  0.304
2010 Gan L. Therapeutic potential and challenges of targeting sirtuins in neurodegenerative diseases Frontiers of Biology in China. 5: 324-330. DOI: 10.1007/s11515-010-0700-7  0.351
2009 Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, Mucke L, Gan L. Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell Stem Cell. 5: 624-33. PMID 19951690 DOI: 10.1016/J.Stem.2009.10.003  0.732
2009 Gan L. Sirtuin signaling in Alzheimer's disease Alzheimers & Dementia. 5: 120. DOI: 10.1016/J.Jalz.2009.05.382  0.359
2008 Sun B, Zhou Y, Halabisky B, Lo I, Cho SH, Mueller-Steiner S, Devidze N, Wang X, Grubb A, Gan L. Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease. Neuron. 60: 247-57. PMID 18957217 DOI: 10.1016/j.neuron.2008.10.001  0.409
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature Neuroscience. 11: 1311-8. PMID 18931664 DOI: 10.1038/Nn.2213  0.767
2008 Gan L, Mucke L. Paths of convergence: sirtuins in aging and neurodegeneration. Neuron. 58: 10-4. PMID 18400158 DOI: 10.1016/j.neuron.2008.03.015  0.541
2008 Sanchez-Mejia RO, Newman JW, Toh S, Yu G, Zhou Y, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. O4-02-03: Phospholipase A2 reduction ameliorates cognitive deficits in mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T186-T187. DOI: 10.1016/J.Jalz.2008.05.511  0.734
2008 Halabisky BE, Sun B, Zhou Y, Mueller-Steiner S, Wang X, Yu G, Mucke L, Gan L. P3-384: Impaired hippocampal adult neurogenesis in an animal model of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1954  0.57
2007 Gan L. Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease. Drug News & Perspectives. 20: 233-9. PMID 17637936 DOI: 10.1358/dnp.2007.20.4.1101162  0.401
2007 Gan L. Therapeutic potential of amyloid β-degrading enzymes in Alzheimer's disease Future Neurology. 2: 133-137. DOI: 10.2217/14796708.2.2.133  0.351
2006 Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L. Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Neuron. 51: 703-14. PMID 16982417 DOI: 10.1016/J.Neuron.2006.07.027  0.614
2006 Gan L, Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Wang X, Chen J, Yu G, Esposito L, Mucke L. O4-06-05: Anti-amyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease Alzheimer's & Dementia. 2: S88-S88. DOI: 10.1016/J.Jalz.2006.05.340  0.566
2005 Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. The Journal of Biological Chemistry. 280: 40364-74. PMID 16183991 DOI: 10.1074/Jbc.M509329200  0.576
2005 Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CA, Whim MD, Yang B. Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels. Hearing Research. 206: 133-45. PMID 16081004 DOI: 10.1016/j.heares.2004.11.023  0.543
2004 Esposito L, Gan L, Yu GQ, Essrich C, Mucke L. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells. Journal of Neurochemistry. 91: 1260-74. PMID 15584903 DOI: 10.1111/j.1471-4159.2004.02816.x  0.572
2004 Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S, Patthy L, Gonzalez-Zulueta M, Nikolich K, Urfer R. Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach. The Journal of Biological Chemistry. 279: 5565-72. PMID 14612454 DOI: 10.1074/Jbc.M306183200  0.406
2002 Bhattacharjee A, Gan L, Kaczmarek LK. Localization of the Slack potassium channel in the rat central nervous system. The Journal of Comparative Neurology. 454: 241-54. PMID 12442315 DOI: 10.1002/cne.10439  0.528
2000 Gan L, Yan J, Yu G, Holden K, Xu X, Mucke L. Opposing effects of the Aβ peptide and its precursor protein on the proapoptotic P53 pathway Neurobiology of Aging. 21: 184. DOI: 10.1016/S0197-4580(00)82167-3  0.528
1999 Gan L, Hahn SJ, Kaczmarek LK. Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter. Journal of Neurochemistry. 73: 1350-62. PMID 10501178 DOI: 10.1046/j.1471-4159.1999.0731350.x  0.542
1999 Xu X, Yang D, Wyss-Coray T, Yan J, Gan L, Sun Y, Mucke L. Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 7547-52. PMID 10377452 DOI: 10.1073/pnas.96.13.7547  0.684
1998 Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits. Nature Neuroscience. 1: 462-9. PMID 10196543 DOI: 10.1038/2176  0.718
1998 Gan L, Kaczmarek LK. When, where, and how much? Expression of the Kv3.1 potassium channel in high-frequency firing neurons. Journal of Neurobiology. 37: 69-79. PMID 9777733 DOI: 10.1002/(SICI)1097-4695(199810)37:1<69::AID-NEU6>3.0.CO;2-6  0.555
1998 Wang LY, Gan L, Perney TM, Schwartz I, Kaczmarek LK. Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion. Proceedings of the National Academy of Sciences of the United States of America. 95: 1882-7. PMID 9465111 DOI: 10.1073/Pnas.95.4.1882  0.615
1996 Gan L, Perney TM, Kaczmarek LK. Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons. The Journal of Biological Chemistry. 271: 5859-65. PMID 8621457 DOI: 10.1074/jbc.271.10.5859  0.543
1995 Kanemasa T, Gan L, Perney TM, Wang LY, Kaczmarek LK. Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts. Journal of Neurophysiology. 74: 207-17. PMID 7472324 DOI: 10.1152/Jn.1995.74.1.207  0.623
Show low-probability matches.