Vasilis Vasiliou - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Toxicology, Biochemistry

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Thompson B, Davidson EA, Liu W, Nebert DW, Bruford EA, Zhao H, Dermitzakis ET, Thompson DC, Vasiliou V. Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease. Human Genetics. PMID 32728807 DOI: 10.1007/S00439-020-02212-9  0.377
2020 Kurniawan H, Franchina DG, Guerra L, Bonetti L, -Baguet LS, Grusdat M, Schlicker L, Hunewald O, Dostert C, Merz MP, Binsfeld C, Duncan GS, Farinelle S, Nonnenmacher Y, Haight J, ... ... Vasiliou V, et al. Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. Cell Metabolism. PMID 32213345 DOI: 10.1016/J.Cmet.2020.03.004  0.337
2019 Alofe O, Kisanga E, Inayat-Hussain SH, Fukumura M, Garcia-Milian R, Perera L, Vasiliou V, Whirledge S. Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions. Environment International. 131: 104969. PMID 31310931 DOI: 10.1016/J.Envint.2019.104969  0.319
2019 Pantouris G, Dioletis E, Chen Y, Thompson DC, Vasiliou V, Lolis EJ. Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1. Chemico-Biological Interactions. PMID 30894314 DOI: 10.1016/J.Cbi.2019.03.009  0.327
2019 Charkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V. Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chemico-Biological Interactions. PMID 30851239 DOI: 10.1016/J.Cbi.2019.02.030  0.317
2019 Charkoftaki G, Wang Y, McAndrews M, Bruford EA, Thompson DC, Vasiliou V, Nebert DW. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Human Genomics. 13: 11. PMID 30782214 DOI: 10.1186/S40246-019-0191-9  0.371
2018 Marshall S, Chen Y, Singh S, Berrios-Carcamo P, Heit C, Apostolopoulos N, Golla JP, Thompson DC, Vasiliou V. Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer. Advances in Experimental Medicine and Biology. 1032: 203-221. PMID 30362100 DOI: 10.1007/978-3-319-98788-0_14  0.325
2018 Chen Y, Han M, Matsumoto A, Wang Y, Thompson DC, Vasiliou V. Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis. Advances in Experimental Medicine and Biology. 1032: 37-53. PMID 30362089 DOI: 10.1007/978-3-319-98788-0_3  0.404
2018 Lian G, Gnanaprakasam JR, Wang T, Wu R, Chen X, Liu L, Shen Y, Yang M, Yang J, Chen Y, Vasiliou V, Cassel TA, Green DR, Liu Y, Fan T, et al. Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation. Elife. 7. PMID 30198844 DOI: 10.7554/Elife.36158  0.325
2018 Yang SM, Martinez NJ, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang AQ, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, ... ... Vasiliou V, et al. Discovery of Orally Bioavailable, Quinoline-based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity. Journal of Medicinal Chemistry. PMID 29767973 DOI: 10.1021/Acs.Jmedchem.8B00270  0.324
2018 Charkoftaki G, Rattray NJW, Andrén PE, Caprioli RM, Castellino S, Duncan MW, Goodwin RJA, Schey KL, Shahidi-Latham SK, Veselkov KA, Johnson CH, Vasiliou V. Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. Human Genomics. 12: 10. PMID 29482659 DOI: 10.1186/S40246-018-0142-X  0.31
2017 Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, ... ... Vasiliou V, et al. Glutathione Primes T Cell Metabolism for Inflammation. Immunity. 46: 675-689. PMID 28423341 DOI: 10.1016/J.Immuni.2017.03.019  0.33
2017 Gasparetto M, Pei S, Minhajuddin M, Khan N, Pollyea DA, Myers JR, Ashton JM, Becker MW, Vasiliou V, Humphries KR, Jordan CT, Smith CA. Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1. Haematologica. PMID 28280079 DOI: 10.3324/Haematol.2016.159053  0.3
2017 Charkoftaki G, Chen Y, Han M, Sandoval M, Yu X, Zhao H, Orlicky DJ, Thompson DC, Vasiliou V. Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function. Chemico-Biological Interactions. PMID 28254523 DOI: 10.1016/J.Cbi.2017.02.013  0.337
2017 Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ. A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. Plos One. 12: e0170937. PMID 28129349 DOI: 10.1371/Journal.Pone.0170937  0.339
2017 Chen Y, Lam TT, Yu X, Vasiliou V. Differential Redox Changes in Liver Mitochondrial Proteomes from Phenotypically Distinct Mouse Models of Glutathione Deficiency Free Radical Biology and Medicine. 112: 22. DOI: 10.1016/J.Freeradbiomed.2017.10.019  0.404
2016 Chen Y, Jester JV, Anderson DM, Marchitti SA, Schey KL, Thompson DC, Vasiliou V. Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry. Chemico-Biological Interactions. PMID 28038895 DOI: 10.1016/J.Cbi.2016.12.017  0.732
2016 Heit C, Marshall S, Singh S, Yu X, Charkoftaki G, Zhao H, Orlicky DJ, Fritz KS, Thompson DC, Vasiliou V. Catalase Deletion Promotes PreDiabetic Phenotype in Mice. Free Radical Biology & Medicine. PMID 27939935 DOI: 10.1016/J.Freeradbiomed.2016.12.011  0.346
2016 Chen Y, Singh S, Matsumoto A, Manna SK, Abdelmegeed MA, Golla S, Murphy RC, Dong H, Song BJ, Gonzalez FJ, Thompson DC, Vasiliou V. Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway. Scientific Reports. 6: 29743. PMID 27403993 DOI: 10.1038/Srep29743  0.388
2016 Matsumoto A, Thompson D, Chen Y, Vasiliou V, Kawamoto T, Ichiba M. Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice. Alcohol (Fayetteville, N.Y.). 52: 49-54. PMID 27139237 DOI: 10.1016/J.Alcohol.2016.02.004  0.363
2016 Koppaka V, Chen Y, Mehta G, Orlicky DJ, Thompson DC, Jester JV, Vasiliou V. ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis. Plos One. 11: e0146433. PMID 26751691 DOI: 10.1371/Journal.Pone.0146433  0.74
2015 Dong H, Nebert DW, Bruford EA, Thompson DC, Joenje H, Vasiliou V. Update of the human and mouse Fanconi anemia genes. Human Genomics. 9: 32. PMID 26596371 DOI: 10.1186/S40246-015-0054-Y  0.352
2015 Jackson BC, Thompson DC, Charkoftaki G, Vasiliou V. Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology. Expert Opinion On Drug Metabolism & Toxicology. 1-9. PMID 26558415 DOI: 10.1517/17425255.2016.1108406  0.392
2015 Yang SM, Yasgar A, Miller B, Lal-Nag M, Brimacombe K, Hu X, Sun H, Wang A, Xu X, Nguyen K, Oppermann U, Ferrer M, Vasiliou V, Simeonov A, Jadhav A, et al. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1). Journal of Medicinal Chemistry. PMID 26207746 DOI: 10.1021/Acs.Jmedchem.5B00577  0.337
2015 Singh S, Chen Y, Matsumoto A, Orlicky DJ, Dong H, Thompson DC, Vasiliou V. ALDH1B1 links alcohol consumption and diabetes. Biochemical and Biophysical Research Communications. 463: 768-73. PMID 26086111 DOI: 10.1016/J.Bbrc.2015.06.011  0.345
2015 Heit C, Dong H, Chen Y, Shah YM, Thompson DC, Vasiliou V. Transgenic mouse models for alcohol metabolism, toxicity, and cancer. Advances in Experimental Medicine and Biology. 815: 375-87. PMID 25427919 DOI: 10.1007/978-3-319-09614-8_22  0.364
2015 Smith C, Gasparetto M, Jordan C, Pollyea DA, Vasiliou V. The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis. Advances in Experimental Medicine and Biology. 815: 349-59. PMID 25427917 DOI: 10.1007/978-3-319-09614-8_20  0.36
2015 Jackson BC, Reigan P, Miller B, Thompson DC, Vasiliou V. Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling. Pharmaceutical Research. 32: 1648-62. PMID 25413692 DOI: 10.1007/S11095-014-1564-3  0.318
2014 Monte AA, Brocker C, Nebert DW, Gonzalez FJ, Thompson DC, Vasiliou V. Improved drug therapy: triangulating phenomics with genomics and metabolomics. Human Genomics. 8: 16. PMID 25181945 DOI: 10.1186/S40246-014-0016-9  0.644
2014 Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP. aldh7a1 regulates eye and limb development in zebrafish. Plos One. 9: e101782. PMID 25004007 DOI: 10.1371/Journal.Pone.0101782  0.672
2014 Smith C, Gasparetto M, Humphries K, Pollyea DA, Vasiliou V, Jordan CT. Aldehyde dehydrogenases in acute myeloid leukemia. Annals of the New York Academy of Sciences. 1310: 58-68. PMID 24641679 DOI: 10.1111/Nyas.12414  0.306
2014 Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T. Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity. Free Radical Biology & Medicine. 68: 80-6. PMID 24316006 DOI: 10.1016/J.Freeradbiomed.2013.11.028  0.334
2014 Gasparetto M, Pei S, Minhajuddin M, Pollyea DA, Vasiliou V, Humphries RK, Jordan CT, Smith CA. Aldehyde Dehydrogenases Play a Role in Acute Myeloid Leukemia and Have Prognostic and Therapeutic Significance Blood. 124: 2238-2238. DOI: 10.1182/Blood.V124.21.2238.2238  0.352
2014 Vasiliou V, Thompson DC, Chen Y. Cellular responses to oxidative stress: From glutathione to aldehyde dehydrogenases Toxicology Letters. 229: S17. DOI: 10.1016/J.Toxlet.2014.06.091  0.342
2013 Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V. Update of the human and mouse SERPIN gene superfamily. Human Genomics. 7: 22. PMID 24172014 DOI: 10.1186/1479-7364-7-22  0.367
2013 Chen Y, Dong H, Thompson DC, Shertzer HG, Nebert DW, Vasiliou V. Glutathione defense mechanism in liver injury: Insights from animal models Food and Chemical Toxicology. 60: 38-44. PMID 23856494 DOI: 10.1016/J.Fct.2013.07.008  0.324
2013 Dong H, Shertzer HG, Genter MB, Gonzalez FJ, Vasiliou V, Jefcoate C, Nebert DW. Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins. Biochemical and Biophysical Research Communications. 435: 727-32. PMID 23692925 DOI: 10.1016/J.Bbrc.2013.05.051  0.334
2013 Vasiliou V, Sandoval M, Backos DS, Jackson BC, Chen Y, Reigan P, Lanaspa MA, Johnson RJ, Koppaka V, Thompson DC. ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1. Chemico-Biological Interactions. 202: 22-31. PMID 23348497 DOI: 10.1016/J.Cbi.2012.12.018  0.722
2013 Jackson BC, Holmes RS, Backos DS, Reigan P, Thompson DC, Vasiliou V. Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2. Chemico-Biological Interactions. 202: 11-21. PMID 23247008 DOI: 10.1016/J.Cbi.2012.11.022  0.388
2013 Bchini R, Vasiliou V, Branlant G, Talfournier F, Rahuel-Clermont S. Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition. Chemico-Biological Interactions. 202: 78-84. PMID 23220587 DOI: 10.1016/J.Cbi.2012.11.019  0.325
2013 Singh S, Brocker C, Koppaka V, Chen Y, Jackson BC, Matsumoto A, Thompson DC, Vasiliou V. Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress. Free Radical Biology & Medicine. 56: 89-101. PMID 23195683 DOI: 10.1016/J.Freeradbiomed.2012.11.010  0.791
2013 Vasiliou V, Thompson DC, Smith C, Fujita M, Chen Y. Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells. Chemico-Biological Interactions. 202: 2-10. PMID 23159885 DOI: 10.1016/J.Cbi.2012.10.026  0.457
2013 Ioannou M, Serafimidis I, Arnes L, Sussel L, Singh S, Vasiliou V, Gavalas A. ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Developmental Biology. 374: 153-63. PMID 23142317 DOI: 10.1016/J.Ydbio.2012.10.030  0.349
2013 Chen Y, Thompson DC, Koppaka V, Jester JV, Vasiliou V. Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision. Progress in Retinal and Eye Research. 33: 28-39. PMID 23098688 DOI: 10.1016/J.Preteyeres.2012.10.001  0.746
2013 Brocker C, Vasiliou M, Carpenter S, Carpenter C, Zhang Y, Wang X, Kotchoni SO, Wood AJ, Kirch HH, Kope?ný D, Nebert DW, Vasiliou V. Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics. Planta. 237: 189-210. PMID 23007552 DOI: 10.1007/S00425-012-1749-0  0.697
2012 Vasiliou V, Nebert DW. A new home for Human Genomics. Human Genomics. 6: 1. PMID 23244372 DOI: 10.1186/1479-7364-6-1  0.304
2012 Brocker C, Thompson DC, Vasiliou V. The role of hyperosmotic stress in inflammation and disease. Biomolecular Concepts. 3: 345-364. PMID 22977648 DOI: 10.1515/Bmc-2012-0001  0.691
2012 Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells (Dayton, Ohio). 30: 2100-13. PMID 22887839 DOI: 10.1002/Stem.1193  0.345
2012 Saw YT, Yang J, Ng SK, Liu S, Singh S, Singh M, Welch WR, Tsuda H, Fong WP, Thompson D, Vasiliou V, Berkowitz RS, Ng SW. Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures. Bmc Cancer. 12: 329. PMID 22852552 DOI: 10.1186/1471-2407-12-329  0.329
2012 Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D, Deitrich RA, Hurley TD, Vasiliou V. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacological Reviews. 64: 520-39. PMID 22544865 DOI: 10.1124/Pr.111.005538  0.748
2012 Black W, Chen Y, Matsumoto A, Thompson DC, Lassen N, Pappa A, Vasiliou V. Molecular mechanisms of ALDH3A1-mediated cellular protection against 4-hydroxy-2-nonenal. Free Radical Biology & Medicine. 52: 1937-44. PMID 22406320 DOI: 10.1016/J.Freeradbiomed.2012.02.050  0.629
2012 Zhang Y, Mao L, Wang H, Brocker C, Yin X, Vasiliou V, Fei Z, Wang X. Genome-wide identification and analysis of grape aldehyde dehydrogenase (ALDH) gene superfamily. Plos One. 7: e32153. PMID 22355416 DOI: 10.1371/Journal.Pone.0032153  0.702
2012 Gasparetto M, Sekulovic S, Brocker C, Tang P, Zakaryan A, Xiang P, Kuchenbauer F, Wen M, Kasaian K, Witty MF, Rosten P, Chen Y, Imren S, Duester G, Thompson DC, ... ... Vasiliou V, et al. Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development. Experimental Hematology. 40: 318-29.e2. PMID 22198153 DOI: 10.1016/J.Exphem.2011.12.006  0.694
2012 Chen Y, Koppaka V, Thompson DC, Vasiliou V. Focus on molecules: ALDH1A1: from lens and corneal crystallin to stem cell marker. Experimental Eye Research. 102: 105-6. PMID 21536030 DOI: 10.1016/J.Exer.2011.04.008  0.675
2011 Jackson BC, Thompson DC, Wright MW, McAndrews M, Bernard A, Nebert DW, Vasiliou V. Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily. Human Genomics. 5: 691-702. PMID 22155607 DOI: 10.1186/1479-7364-5-6-691  0.369
2011 Khanna M, Chen CH, Kimble-Hill A, Parajuli B, Perez-Miller S, Baskaran S, Kim J, Dria K, Vasiliou V, Mochly-Rosen D, Hurley TD. Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases. The Journal of Biological Chemistry. 286: 43486-94. PMID 22021038 DOI: 10.1074/Jbc.M111.293597  0.369
2011 Jackson B, Brocker C, Thompson DC, Black W, Vasiliou K, Nebert DW, Vasiliou V. Update on the aldehyde dehydrogenase gene (ALDH) superfamily. Human Genomics. 5: 283-303. PMID 21712190 DOI: 10.1186/1479-7364-5-4-283  0.719
2011 Marchitti SA, Chen Y, Thompson DC, Vasiliou V. Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes. Eye & Contact Lens. 37: 206-13. PMID 21670692 DOI: 10.1097/Icl.0B013E3182212642  0.763
2011 Brocker C, Cantore M, Failli P, Vasiliou V. Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. Chemico-Biological Interactions. 191: 269-77. PMID 21338592 DOI: 10.1016/J.Cbi.2011.02.016  0.731
2011 Oraldi M, Saracino S, Maggiora M, Chiaravalloti A, Buemi C, Martinasso G, Paiuzzi E, Thompson D, Vasiliou V, Canuto RA. Importance of inverse correlation between ALDH3A1 and PPARγ in tumor cells and tissue regeneration Chemico-Biological Interactions. 191: 171-176. PMID 21251908 DOI: 10.1016/J.Cbi.2011.01.011  0.374
2011 Chen Y, Orlicky DJ, Matsumoto A, Singh S, Thompson DC, Vasiliou V. Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer. Biochemical and Biophysical Research Communications. 405: 173-9. PMID 21216231 DOI: 10.1016/J.Bbrc.2011.01.002  0.362
2010 Estey T, Chen Y, Carpenter JF, Vasiliou V. Structural and functional modifications of corneal crystallin ALDH3A1 by UVB light. Plos One. 5: e15218. PMID 21203538 DOI: 10.1371/Journal.Pone.0015218  0.347
2010 Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V. Evolutionary divergence and functions of the human interleukin (IL) gene family. Human Genomics. 5: 30-55. PMID 21106488 DOI: 10.1186/1479-7364-5-1-30  0.648
2010 Brocker C, Carpenter C, Nebert DW, Vasiliou V. Evolutionary divergence and functions of the human acyl-CoA thioesterase gene ( ACOT ) family. Human Genomics. 4: 411-20. PMID 20846931 DOI: 10.1186/1479-7364-4-6-411  0.707
2010 Scharer G, Brocker C, Vasiliou V, Creadon-Swindell G, Gallagher RC, Spector E, Van Hove JL. The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1. Journal of Inherited Metabolic Disease. 33: 571-81. PMID 20814824 DOI: 10.1007/S10545-010-9187-2  0.647
2010 Marchitti SA, Orlicky DJ, Brocker C, Vasiliou V. Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 58: 765-83. PMID 20729348 DOI: 10.1369/Jhc.2010.955773  0.786
2010 Marchitti SA, Brocker C, Orlicky DJ, Vasiliou V. Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress. Free Radical Biology & Medicine. 49: 1432-43. PMID 20699116 DOI: 10.1016/J.Freeradbiomed.2010.08.004  0.787
2010 Jackson BC, Carpenter C, Nebert DW, Vasiliou V. Update of human and mouse forkhead box (FOX) gene families. Human Genomics. 4: 345-52. PMID 20650821 DOI: 10.1186/1479-7364-4-5-345  0.373
2010 Stagos D, Chen Y, Brocker C, Donald E, Jackson BC, Orlicky DJ, Thompson DC, Vasiliou V. Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1679-87. PMID 20616185 DOI: 10.1124/Dmd.110.034678  0.728
2010 Brocker C, Lassen N, Estey T, Pappa A, Cantore M, Orlova VV, Chavakis T, Kavanagh KL, Oppermann U, Vasiliou V. Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. The Journal of Biological Chemistry. 285: 18452-63. PMID 20207735 DOI: 10.1074/Jbc.M109.077925  0.779
2010 Stagos D, Chen Y, Cantore M, Jester JV, Vasiliou V. Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization. Brain Research Bulletin. 81: 211-8. PMID 19720116 DOI: 10.1016/J.Brainresbull.2009.08.017  0.453
2010 Brocker C, Carpenter C, Nebert DW, Vasiliou V. Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family Human Genomics. DOI: 10.1186/1479-7364-4-6-411  0.686
2009 Black W, Vasiliou V. The aldehyde dehydrogenase gene superfamily resource center. Human Genomics. 4: 136-42. PMID 20038501 DOI: 10.1186/1479-7364-4-2-136  0.328
2009 Brocker CN, Vasiliou V, Nebert DW. Evolutionary divergence and functions of the ADAM and ADAMTS gene families. Human Genomics. 4: 43-55. PMID 19951893 DOI: 10.1186/1479-7364-4-1-43  0.699
2009 Chen Y, Mehta G, Vasiliou V. Antioxidant defenses in the ocular surface. The Ocular Surface. 7: 176-85. PMID 19948101 DOI: 10.1016/S1542-0124(12)70185-4  0.365
2009 Black WJ, Stagos D, Marchitti SA, Nebert DW, Tipton KF, Bairoch A, Vasiliou V. Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature. Pharmacogenetics and Genomics. 19: 893-902. PMID 19823103 DOI: 10.1097/Fpc.0B013E3283329023  0.749
2009 Endo J, Sano M, Katayama T, Hishiki T, Shinmura K, Morizane S, Matsuhashi T, Katsumata Y, Zhang Y, Ito H, Nagahata Y, Marchitti S, Nishimaki K, Wolf AM, Nakanishi H, ... ... Vasiliou V, et al. Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart. Circulation Research. 105: 1118-27. PMID 19815821 DOI: 10.1161/Circresaha.109.206607  0.73
2009 Chen Y, Johansson E, Fan Y, Shertzer HG, Vasiliou V, Nebert DW, Dalton TP. Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit. Free Radical Biology & Medicine. 47: 410-8. PMID 19427898 DOI: 10.1016/J.Freeradbiomed.2009.05.003  0.34
2009 Xiao T, Shoeb M, Siddiqui MS, Zhang M, Ramana KV, Srivastava SK, Vasiliou V, Ansari NH. Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes. Journal of Toxicology and Environmental Health. Part A. 72: 577-84. PMID 19296407 DOI: 10.1080/15287390802706371  0.423
2009 D'Amelio S, Lassen N, Vasiliou V, Bateman JB. Duane retraction syndrome, nystagmus, retinal pigment epitheliopathy and epiretinal membrane with micro- and pachygyria, developmental delay, hearing loss and craniopharyngioma. Ophthalmic Genetics. 30: 7-12. PMID 19172504 DOI: 10.1080/13816810802415249  0.477
2009 Stagos D, Zhou H, Ross D, Vasiliou V. 4-HNE inhibits tube formation and up-regulates chondromodulin-I in human endothelial cells. Biochemical and Biophysical Research Communications. 379: 654-8. PMID 19056352 DOI: 10.1016/J.Bbrc.2008.11.095  0.338
2008 Marchitti SA, Brocker C, Stagos D, Vasiliou V. Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily. Expert Opinion On Drug Metabolism & Toxicology. 4: 697-720. PMID 18611112 DOI: 10.1517/17425255.4.6.697  0.78
2008 Lassen N, Black WJ, Estey T, Vasiliou V. The role of corneal crystallins in the cellular defense mechanisms against oxidative stress. Seminars in Cell & Developmental Biology. 19: 100-12. PMID 18077195 DOI: 10.1016/J.Semcdb.2007.10.004  0.593
2008 Vasiliou V, Gonzalez FJ. Role of CYP1B1 in glaucoma. Annual Review of Pharmacology and Toxicology. 48: 333-58. PMID 17914928 DOI: 10.1146/Annurev.Pharmtox.48.061807.154729  0.358
2008 Marchitti SA, Bateman JB, Petrash JM, Vasiliou V. Mouse Models of The Cornea And Lens: Understanding Ocular Disease Animal Models in Eye Research. 148-172. DOI: 10.1016/B978-0-12-374169-1.00011-4  0.714
2007 Deitrich RA, Petersen D, Vasiliou V. Removal of acetaldehyde from the body. Novartis Foundation Symposium. 285: 23-40; discussion 40. PMID 17590985 DOI: 10.1002/9780470511848.Ch3  0.42
2007 Lassen N, Bateman JB, Estey T, Kuszak JR, Nees DW, Piatigorsky J, Duester G, Day BJ, Huang J, Hines LM, Vasiliou V. Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice. The Journal of Biological Chemistry. 282: 25668-76. PMID 17567582 DOI: 10.1074/Jbc.M702076200  0.55
2007 Jia S, Omelchenko M, Garland D, Vasiliou V, Kanungo J, Spencer M, Wolf Y, Koonin E, Piatigorsky J. Duplicated gelsolin family genes in zebrafish: a novel scinderin-like gene (scinla) encodes the major corneal crystallin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3318-28. PMID 17548429 DOI: 10.1096/Fj.07-8172Com  0.327
2007 Marchitti SA, Orlicky DJ, Vasiliou V. Expression and initial characterization of human ALDH3B1. Biochemical and Biophysical Research Communications. 356: 792-8. PMID 17382292 DOI: 10.1016/J.Bbrc.2007.03.046  0.776
2007 Marchitti SA, Deitrich RA, Vasiliou V. Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacological Reviews. 59: 125-50. PMID 17379813 DOI: 10.1124/Pr.59.2.1  0.762
2007 Estey T, Cantore M, Weston PA, Carpenter JF, Petrash JM, Vasiliou V. Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1. The Journal of Biological Chemistry. 282: 4382-92. PMID 17158879 DOI: 10.1074/Jbc.M607546200  0.393
2007 Estey T, Piatigorsky J, Lassen N, Vasiliou V. ALDH3A1: a corneal crystallin with diverse functions. Experimental Eye Research. 84: 3-12. PMID 16797007 DOI: 10.1016/J.Exer.2006.04.010  0.604
2006 Lassen N, Pappa A, Black WJ, Jester JV, Day BJ, Min E, Vasiliou V. Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts. Free Radical Biology & Medicine. 41: 1459-69. PMID 17023273 DOI: 10.1016/J.Freeradbiomed.2006.08.009  0.589
2006 Bhave SV, Hoffman PL, Lassen N, Vasiliou V, Saba L, Deitrich RA, Tabakoff B. Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice. Alcoholism, Clinical and Experimental Research. 30: 1659-69. PMID 17010133 DOI: 10.1111/J.1530-0277.2006.00201.X  0.543
2006 Muzio G, Trombetta A, Maggiora M, Martinasso G, Vasiliou V, Lassen N, Canuto RA. Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression. Free Radical Biology & Medicine. 40: 1929-38. PMID 16716894 DOI: 10.1016/J.Freeradbiomed.2006.01.020  0.548
2006 Vasiliou V, Ross D, Nebert DW. Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family. Human Genomics. 2: 329-35. PMID 16595077 DOI: 10.1186/1479-7364-2-5-329  0.394
2006 Panayiotidis MI, Stabler SP, Ahmad A, Pappa A, Legros LH, Hernandez-Saavedra D, Schneider BK, Allen RH, Vasiliou V, McCord JM, Kotb M, White CW. Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. Free Radical Biology & Medicine. 40: 348-58. PMID 16413417 DOI: 10.1016/J.Freeradbiomed.2005.09.004  0.317
2005 Vasiliou V, Nebert DW. Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family. Human Genomics. 2: 138-43. PMID 16004729 DOI: 10.1186/1479-7364-2-2-138  0.421
2005 Pappa A, Brown D, Koutalos Y, DeGregori J, White C, Vasiliou V. Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. The Journal of Biological Chemistry. 280: 27998-8006. PMID 15905174 DOI: 10.1074/Jbc.M503698200  0.404
2005 Kenney MC, Chwa M, Atilano SR, Tran A, Carballo M, Saghizadeh M, Vasiliou V, Adachi W, Brown DJ. Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder. Investigative Ophthalmology & Visual Science. 46: 823-32. PMID 15728537 DOI: 10.1167/Iovs.04-0549  0.324
2005 Lassen N, Estey T, Tanguay RL, Pappa A, Reimers MJ, Vasiliou V. Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 649-56. PMID 15703303 DOI: 10.1124/Dmd.104.002964  0.586
2005 Black W, Vasiliou V. Ocular metabolism and disposition of 4-hydroxy-2-nonenal Cutaneous and Ocular Toxicology. 24: 165-176. DOI: 10.1080/15569520500278906  0.355
2004 Nebert DW, Vasiliou V. Analysis of the glutathione S-transferase (GST) gene family. Human Genomics. 1: 460-4. PMID 15607001 DOI: 10.1186/1479-7364-1-6-460  0.363
2004 Mashek DG, Bornfeldt KE, Coleman RA, Berger J, Bernlohr DA, Black P, DiRusso CC, Farber SA, Guo W, Hashimoto N, Khodiyar V, Kuypers FA, Maltais LJ, Nebert DW, Renieri A, ... ... Vasiliou V, et al. Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. Journal of Lipid Research. 45: 1958-61. PMID 15292367 DOI: 10.1194/Jlr.E400002-Jlr200  0.303
2004 Vasiliou V, Pappa A, Estey T. Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism. Drug Metabolism Reviews. 36: 279-99. PMID 15237855 DOI: 10.1081/Dmr-120034001  0.416
2003 DiFabio J, Ji Y, Vasiliou V, Thatcher GR, Bennett BM. Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance. Molecular Pharmacology. 64: 1109-16. PMID 14573760 DOI: 10.1124/Mol.64.5.1109  0.356
2003 Pappa A, Estey T, Manzer R, Brown D, Vasiliou V. Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea. The Biochemical Journal. 376: 615-23. PMID 12943535 DOI: 10.1042/Bj20030810  0.43
2003 Manzer R, Qamar L, Estey T, Pappa A, Petersen DR, Vasiliou V. Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA. Dna and Cell Biology. 22: 329-38. PMID 12941160 DOI: 10.1089/104454903322216671  0.392
2003 Vasiliou V, Qamar L, Pappa A, Sophos NA, Petersen DR. Involvement of the electrophile responsive element and p53 in the activation of hepatic stellate cells as a response to electrophile menadione. Archives of Biochemistry and Biophysics. 413: 164-71. PMID 12729613 DOI: 10.1016/S0003-9861(03)00095-X  0.358
2003 Pappa A, Chen C, Koutalos Y, Townsend AJ, Vasiliou V. Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage. Free Radical Biology & Medicine. 34: 1178-89. PMID 12706498 DOI: 10.1016/S0891-5849(03)00070-4  0.397
2003 Manzer R, Pappa A, Estey T, Sladek N, Carpenter JF, Vasiliou V. Ultraviolet radiation decreases expression and induces aggregation of corneal ALDH3A1. Chemico-Biological Interactions. 143: 45-53. PMID 12604188 DOI: 10.1016/S0009-2797(02)00171-0  0.337
2003 Sophos NA, Vasiliou V. Aldehyde dehydrogenase gene superfamily: the 2002 update. Chemico-Biological Interactions. 143: 5-22. PMID 12604184 DOI: 10.1016/S0009-2797(02)00163-1  0.359
2001 Sophos NA, Pappa A, Ziegler TL, Vasiliou V. Aldehyde dehydrogenase gene superfamily: The 2000 update Chemico-Biological Interactions. 130: 323-337. PMID 11306055 DOI: 10.1016/S0009-2797(00)00275-1  0.354
2001 Pappas P, Stephanou P, Karamanakos P, Vasiliou V, Marselos M. Phenobarbital inducibility and differences in protein expression of an animal model Chemico-Biological Interactions. 130: 275-283. PMID 11306051 DOI: 10.1016/S0009-2797(00)00271-4  0.376
2001 Pappa A, Sophos NA, Vasiliou V. Corneal and stomach expression of aldehyde dehydrogenases: From fish to mammals Chemico-Biological Interactions. 130: 181-191. PMID 11306042 DOI: 10.1016/S0009-2797(00)00233-7  0.368
2000 Vasiliou V, Pappa A, Petersen DR. Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism Chemico-Biological Interactions. 129: 1-19. PMID 11154732 DOI: 10.1016/S0009-2797(00)00211-8  0.404
2000 Vasiliou V, Pappa A. Polymorphisms of human aldehyde dehydrogenases: Consequences for drug metabolism and disease Pharmacology. 61: 192-198. PMID 10971205 DOI: 10.1159/000028400  0.388
2000 Vasiliou V, Buetler T, Eaton DL, Nebert DW. Comparison of oxidative stress response parameters in newborn mouse liver versus simian virus 40 (SV40)-transformed hepatocyte cell lines Biochemical Pharmacology. 59: 703-712. PMID 10677587 DOI: 10.1016/S0006-2952(99)00360-3  0.323
1999 Vasiliou V, Reuter SF, Williams S, Puga A, Nebert DW. Mouse cytosolic class 3 aldehyde dehydrogenase (Aldh3a1): Gene structure and regulation of constitutive and dioxin-inducible expression Pharmacogenetics. 9: 569-580. PMID 10591537 DOI: 10.1097/00008571-199910000-00004  0.369
1999 Vasiliou V, Shiao T. The lack of AHD4 induction by TCDD in corneal cells may involve tissue-specific regulatory proteins Advances in Experimental Medicine and Biology. 463: 181-188. PMID 10352684 DOI: 10.1007/978-1-4615-4735-8_22  0.325
1999 Stephanou P, Pappas P, Vasiliou V, Marselos M. Prepubertal regulation of the rat dioxin-inducible aldehyde dehydrogenase (ALDH3) Advances in Experimental Medicine and Biology. 463: 143-150. PMID 10352679 DOI: 10.1007/978-1-4615-4735-8_17  0.359
1998 Pappas P, Stephanou P, Vasiliou V, Marselos M. Anti-inflammatory agents and inducibility of hepatic drug metabolism European Journal of Drug Metabolism and Pharmacokinetics. 23: 457-460. PMID 10323327 DOI: 10.1007/Bf03189995  0.336
1997 Marks-Hull H, Shiao TY, Araki-Sasaki K, Traver R, Vasiliou V. Expression of ALDH3 and NMO1 in human corneal epithelial and breast adenocarcinoma cells. Advances in Experimental Medicine and Biology. 414: 59-68. PMID 9059607 DOI: 10.1007/978-1-4615-5871-2_8  0.355
1996 Vasiliou V, Kozak CA, Lindahl R, Nebert DW. Mouse microsomal Class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, inducibility by dioxin and clofibrate, and genetic mapping. Dna and Cell Biology. 15: 235-45. PMID 8634152 DOI: 10.1089/Dna.1996.15.235  0.359
1995 Vasiliou V, Puga A, Chang CY, Tabor MW, Nebert DW. Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression Biochemical Pharmacology. 50: 2057-2068. PMID 8849333 DOI: 10.1016/0006-2952(95)02108-6  0.337
1995 Vasiliou V, Shertzer HG, Liu RM, Sainsbury M, Nebert DW. Response of [Ah] battery genes to compounds that protect against menadione toxicity Biochemical Pharmacology. 50: 1885-1891. PMID 8615869 DOI: 10.1016/0006-2952(95)02083-7  0.362
1995 Vasiliou V, Reuter SF, Kozak CA, Nebert DW. Mouse class 3 aldehyde dehydrogenases. Advances in Experimental Medicine and Biology. 372: 151-8. PMID 7484373 DOI: 10.1007/978-1-4615-1965-2_20  0.328
1995 Shertzer HG, Vasiliou V, Liu RM, Tabor MW, Nebert DW. Enzyme induction by l-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells Chemical Research in Toxicology. 8: 431-436. DOI: 10.1021/Tx00045A015  0.371
1994 Pappas P, Vasiliou V, Nebert DW, Marselos M. Lack of response of the rat liver "class 3" cytosolic aldehyde dehydrogenase to toxic chemicals, glutathione depletion, and other forms of stress Biochemical Pharmacology. 48: 841-845. PMID 8080457 DOI: 10.1016/0006-2952(94)90064-7  0.311
1994 Vasiliou V, Theurer MJ, Puga A, Reuter SF, Nebert DW. Mouse dioxin-inducible NAD(P)H: Menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels Pharmacogenetics. 4: 341-348. PMID 7704040 DOI: 10.1097/00008571-199412000-00007  0.395
1993 Vasiliou V, Puga A, Nebert DW. Mouse class 3 aldehyde dehydrogenases: Positive and negative regulation of gene expression Advances in Experimental Medicine and Biology. 328: 131-140. PMID 8493891 DOI: 10.1007/978-1-4615-2904-0_15  0.323
1993 Nebert DW, Puga A, Vasiliou V. Roel of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction Annals of the New York Academy of Sciences. 685: 624-640. PMID 8395783 DOI: 10.1111/J.1749-6632.1993.Tb35928.X  0.389
1993 Vasiliou V, Reuter SF, Kozak CA, Nebert DW. Mouse dioxin-inducible cytosolic aldehyde dehydrogenase-3: AHD4 cDNA sequence, genetic mapping, and differences in mrna levels Pharmacogenetics. 3: 281-290. PMID 8148869 DOI: 10.1097/00008571-199312000-00002  0.361
1992 Vasiliou V, Puga A, Nebert DW. Negative regulation of the murine cytosolic aldehyde dehydrogenase-3 (Aldh-3c) gene by functional CYP1A1 and CYP1A2 proteins Biochemical and Biophysical Research Communications. 187: 413-419. PMID 1520328 DOI: 10.1016/S0006-291X(05)81508-6  0.404
1989 Vasiliou V, Marselos M. Tissue Distribution of Inducible Aldehyde Dehydrogenase Activity in the Rat after Treatment with Phenobarbital or Methylcholanthrene Pharmacology &Amp; Toxicology. 64: 39-42. PMID 2755909 DOI: 10.1111/J.1600-0773.1989.Tb00597.X  0.302
1989 Vasiliou V, Törrönen R, Malamas M, Marselos M. Inducibility of liver cytosolic aldehyde dehydrogenase activity in various animal species Comparative Biochemistry and Physiology. Part C, Comparative. 94: 671-675. PMID 2576795 DOI: 10.1016/0742-8413(89)90130-8  0.349
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