Thomas S. Whittam - Publications

Affiliations: 
Michigan State University, East Lansing, MI 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Hazen TH, Sahl JW, Redman JC, Morris CR, Daugherty SC, Chibucos MC, Sengamalay NA, Fraser-Liggett CM, Steinsland H, Whittam TS, Whittam B, Manning SD, Rasko DA. Draft genome sequences of the diarrheagenic Escherichia coli collection. Journal of Bacteriology. 194: 3026-7. PMID 22582382 DOI: 10.1128/Jb.00426-12  0.409
2011 Leopold SR, Sawyer SA, Whittam TS, Tarr PI. Obscured phylogeny and possible recombinational dormancy in Escherichia coli. Bmc Evolutionary Biology. 11: 183. PMID 21708031 DOI: 10.1186/1471-2148-11-183  0.459
2010 Steinsland H, Lacher DW, Sommerfelt H, Whittam TS. Ancestral lineages of human enterotoxigenic Escherichia coli. Journal of Clinical Microbiology. 48: 2916-24. PMID 20534806 DOI: 10.1128/Jcm.02432-09  0.748
2010 Feng PC, Keys C, Lacher D, Monday SR, Shelton D, Rozand C, Rivas M, Whittam T. Prevalence, characterization and clonal analysis of Escherichia coli O157: non-H7 serotypes that carry eae alleles. Fems Microbiology Letters. 308: 62-7. PMID 20487015 DOI: 10.1111/J.1574-6968.2010.01990.X  0.76
2010 Abu-Ali GS, Ouellette LM, Henderson ST, Lacher DW, Riordan JT, Whittam TS, Manning SD. Increased adherence and expression of virulence genes in a lineage of Escherichia coli O157:H7 commonly associated with human infections. Plos One. 5: e10167. PMID 20422047 DOI: 10.1371/Journal.Pone.0010167  0.848
2010 Oaks JL, Besser TE, Walk ST, Gordon DM, Beckmen KB, Burek KA, Haldorson GJ, Bradway DS, Ouellette L, Rurangirwa FR, Davis MA, Dobbin G, Whittam TS. Escherichia albertii in wild and domestic birds. Emerging Infectious Diseases. 16: 638-46. PMID 20350378 DOI: 10.3201/Eid1604.090695  0.721
2010 Riordan JT, Tietjen JA, Walsh CW, Gustafson JE, Whittam TS. Inactivation of alternative sigma factor 54 (RpoN) leads to increased acid resistance, and alters locus of enterocyte effacement (LEE) expression in Escherichia coli O157 : H7. Microbiology (Reading, England). 156: 719-30. PMID 19942657 DOI: 10.1099/Mic.0.032631-0  0.499
2010 Abu-Ali GS, Ouellette LM, Henderson ST, Whittam TS, Manning SD. Differences in adherence and virulence gene expression between two outbreak strains of enterohaemorrhagic Escherichia coli O157 : H7. Microbiology (Reading, England). 156: 408-19. PMID 19892762 DOI: 10.1099/Mic.0.033126-0  0.818
2010 Vanaja SK, Springman AC, Besser TE, Whittam TS, Manning SD. Differential expression of virulence and stress fitness genes between Escherichia coli O157:H7 strains with clinical or bovine-biased genotypes. Applied and Environmental Microbiology. 76: 60-8. PMID 19880650 DOI: 10.1128/Aem.01666-09  0.58
2010 Cho S, Whittam TS, Boxrud DJ, Bartkus JM, Rankin SC, Wilkins MJ, Somsel P, Downes FP, Musser KA, Root TP, Warnick LD, Wiedmann M, Saeed AM. Use of multiple-locus variable number tandem repeat analysis and phage typing for subtyping of Salmonella Enteritidis from sporadic human cases in the United States. Journal of Applied Microbiology. 108: 859-67. PMID 19709332 DOI: 10.1111/J.1365-2672.2009.04492.X  0.341
2009 Walk ST, Alm EW, Gordon DM, Ram JL, Toranzos GA, Tiedje JM, Whittam TS. Cryptic lineages of the genus Escherichia. Applied and Environmental Microbiology. 75: 6534-44. PMID 19700542 DOI: 10.1128/Aem.01262-09  0.711
2009 Springman AC, Lacher DW, Wu G, Milton N, Whittam TS, Davies HD, Manning SD. Selection, recombination, and virulence gene diversity among group B streptococcal genotypes. Journal of Bacteriology. 191: 5419-27. PMID 19581371 DOI: 10.1128/Jb.00369-09  0.739
2009 Abu-Ali GS, Lacher DW, Wick LM, Qi W, Whittam TS. Genomic diversity of pathogenic Escherichia coli of the EHEC 2 clonal complex. Bmc Genomics. 10: 296. PMID 19575794 DOI: 10.1186/1471-2164-10-296  0.833
2009 Kulasekara BR, Jacobs M, Zhou Y, Wu Z, Sims E, Saenphimmachak C, Rohmer L, Ritchie JM, Radey M, McKevitt M, Freeman TL, Hayden H, Haugen E, Gillett W, Fong C, ... ... Whittam TS, et al. Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infection and Immunity. 77: 3713-21. PMID 19564389 DOI: 10.1128/Iai.00198-09  0.602
2009 Springman AC, Jacobs JL, Somvanshi VS, Sundin GW, Mulks MH, Whittam TS, Viswanathan P, Gray RL, Lipuma JJ, Ciche TA. Genetic diversity and multihost pathogenicity of clinical and environmental strains of Burkholderia cenocepacia. Applied and Environmental Microbiology. 75: 5250-60. PMID 19542323 DOI: 10.1128/Aem.00877-09  0.414
2009 Tennant SM, Tauschek M, Azzopardi K, Bigham A, Bennett-Wood V, Hartland EL, Qi W, Whittam TS, Robins-Browne RM. Characterisation of atypical enteropathogenic E. coli strains of clinical origin. Bmc Microbiology. 9: 117. PMID 19490652 DOI: 10.1186/1471-2180-9-117  0.749
2009 Leopold SR, Magrini V, Holt NJ, Shaikh N, Mardis ER, Cagno J, Ogura Y, Iguchi A, Hayashi T, Mellmann A, Karch H, Besser TE, Sawyer SA, Whittam TS, Tarr PI. A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 8713-8. PMID 19439656 DOI: 10.1073/Pnas.0812949106  0.493
2009 Bergholz TM, Vanaja SK, Whittam TS. Gene expression induced in Escherichia coli O157:H7 upon exposure to model apple juice. Applied and Environmental Microbiology. 75: 3542-53. PMID 19346340 DOI: 10.1128/Aem.02841-08  0.734
2009 Bell JA, St Charles JL, Murphy AJ, Rathinam VA, Plovanich-Jones AE, Stanley EL, Wolf JE, Gettings JR, Whittam TS, Mansfield LS. Multiple factors interact to produce responses resembling spectrum of human disease in Campylobacter jejuni infected C57BL/6 IL-10-/- mice. Bmc Microbiology. 9: 57. PMID 19296832 DOI: 10.1186/1471-2180-9-57  0.385
2009 Newton HJ, Sloan J, Bulach DM, Seemann T, Allison CC, Tauschek M, Robins-Browne RM, Paton JC, Whittam TS, Paton AW, Hartland EL. Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement. Emerging Infectious Diseases. 15: 372-80. PMID 19239748 DOI: 10.3201/Eid1502.080631  0.614
2009 Manning SD, Springman AC, Lehotzky E, Lewis MA, Whittam TS, Davies HD. Multilocus sequence types associated with neonatal group B streptococcal sepsis and meningitis in Canada. Journal of Clinical Microbiology. 47: 1143-8. PMID 19158264 DOI: 10.1128/Jcm.01424-08  0.457
2009 McNamara SE, Srinivasan U, Zhang L, Whittam TS, Marrs CF, Foxman B. Comparison of probe hybridization array typing to multilocus sequence typing for pathogenic Escherichia coli. Journal of Clinical Microbiology. 47: 596-602. PMID 19144816 DOI: 10.1128/Jcm.01693-08  0.457
2009 Kailasan Vanaja S, Bergholz TM, Whittam TS. Characterization of the Escherichia coli O157:H7 Sakai GadE regulon. Journal of Bacteriology. 191: 1868-77. PMID 19114477 DOI: 10.1128/Jb.01481-08  0.79
2008 Cho S, Whittam TS, Boxrud DJ, Bartkus JM, Saeed AM. Allele distribution and genetic diversity of VNTR loci in Salmonella enterica serotype Enteritidis isolates from different sources. Bmc Microbiology. 8: 146. PMID 18793420 DOI: 10.1186/1471-2180-8-146  0.372
2008 Jacobson MJ, Lin G, Whittam TS, Johnson EA. Phylogenetic analysis of Clostridium botulinum type A by multi-locus sequence typing. Microbiology (Reading, England). 154: 2408-15. PMID 18667573 DOI: 10.1099/Mic.0.2008/016915-0  0.464
2008 Hazbón MH, Motiwala AS, Cavatore M, Brimacombe M, Whittam TS, Alland D. Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 52: 3369-76. PMID 18591265 DOI: 10.1128/Aac.00309-08  0.323
2008 Konczy P, Ziebell K, Mascarenhas M, Choi A, Michaud C, Kropinski AM, Whittam TS, Wickham M, Finlay B, Karmali MA. Genomic O island 122, locus for enterocyte effacement, and the evolution of virulent verocytotoxin-producing Escherichia coli. Journal of Bacteriology. 190: 5832-40. PMID 18586943 DOI: 10.1128/Jb.00480-08  0.59
2008 Schlager TA, Johnson JR, Ouellette LM, Whittam TS. Escherichia coli colonizing the neurogenic bladder are similar to widespread clones causing disease in patients with normal bladder function. Spinal Cord. 46: 633-8. PMID 18560376 DOI: 10.1038/Sc.2008.60  0.475
2008 Manning SD, Schaeffer KE, Springman AC, Lehotzky E, Lewis MA, Ouellette LM, Wu G, Moorer GM, Whittam TS, Davies HD. Genetic diversity and antimicrobial resistance in group B streptococcus colonizing young, nonpregnant women. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47: 388-90. PMID 18558880 DOI: 10.1086/589864  0.376
2008 Manning SD, Lewis MA, Springman AC, Lehotzky E, Whittam TS, Davies HD. Genotypic diversity and serotype distribution of group B streptococcus isolated from women before and after delivery. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 46: 1829-37. PMID 18462173 DOI: 10.1086/588296  0.406
2008 Eaton KA, Friedman DI, Francis GJ, Tyler JS, Young VB, Haeger J, Abu-Ali G, Whittam TS. Pathogenesis of renal disease due to enterohemorrhagic Escherichia coli in germ-free mice. Infection and Immunity. 76: 3054-63. PMID 18443087 DOI: 10.1128/Iai.01626-07  0.749
2008 Riordan JT, Viswanath SB, Manning SD, Whittam TS. Genetic differentiation of Escherichia coli O157:H7 clades associated with human disease by real-time PCR. Journal of Clinical Microbiology. 46: 2070-3. PMID 18400915 DOI: 10.1128/Jcm.00203-08  0.545
2008 Manning SD, Motiwala AS, Springman AC, Qi W, Lacher DW, Ouellette LM, Mladonicky JM, Somsel P, Rudrik JT, Dietrich SE, Zhang W, Swaminathan B, Alland D, Whittam TS. Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks. Proceedings of the National Academy of Sciences of the United States of America. 105: 4868-73. PMID 18332430 DOI: 10.1073/Pnas.0710834105  0.827
2008 Ziebell K, Konczy P, Yong I, Frost S, Mascarenhas M, Kropinski AM, Whittam TS, Read SC, Karmali MA. Applicability of phylogenetic methods for characterizing the public health significance of verocytotoxin-producing Escherichia coli strains. Applied and Environmental Microbiology. 74: 1671-5. PMID 18165362 DOI: 10.1128/Aem.01619-07  0.494
2008 Tarr CL, Nelson AM, Beutin L, Olsen KE, Whittam TS. Molecular characterization reveals similar virulence gene content in unrelated clonal groups of Escherichia coli of serogroup O174 (OX3). Journal of Bacteriology. 190: 1344-9. PMID 18083801 DOI: 10.1128/Jb.01317-07  0.734
2008 Besser TE, Shaikh N, Holt NJ, Tarr PI, Konkel ME, Malik-Kale P, Walsh CW, Whittam TS, Bono JL. Greater diversity of shiga toxin-encoding bacteriophage insertion sites among Escherichia coli O157:H7 isolates from cattle than in those from humans (Applied and Environmental Microbiology (2007) 73, 3, (671-679)) Applied and Environmental Microbiology. 74: 554. DOI: 10.1128/Aem.02632-07  0.422
2008 Eaton KA, Friedman DI, Francis GJ, Young VB, Haeger J, Whittam TS, Tyler JS, Abu-Ali G. W1781 The Pathogenesis of Renal Disease Due to Enterohemorrhagic E. coli in Germ Free Mice Gastroenterology. 134: A-714. DOI: 10.1016/S0016-5085(08)63335-1  0.697
2007 Feng PC, Monday SR, Lacher DW, Allison L, Siitonen A, Keys C, Eklund M, Nagano H, Karch H, Keen J, Whittam TS. Genetic diversity among clonal lineages within Escherichia coli O157:H7 stepwise evolutionary model. Emerging Infectious Diseases. 13: 1701-6. PMID 18217554 DOI: 10.3201/Eid1311.070381  0.764
2007 Bergholz TM, Wick LM, Qi W, Riordan JT, Ouellette LM, Whittam TS. Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium. Bmc Microbiology. 7: 97. PMID 17967175 DOI: 10.1186/1471-2180-7-97  0.806
2007 Walk ST, Mladonicky JM, Middleton JA, Heidt AJ, Cunningham JR, Bartlett P, Sato K, Whittam TS. Influence of antibiotic selection on genetic composition of Escherichia coli populations from conventional and organic dairy farms. Applied and Environmental Microbiology. 73: 5982-9. PMID 17704272 DOI: 10.1128/Aem.00709-07  0.668
2007 Cho S, Boxrud DJ, Bartkus JM, Whittam TS, Saeed M. Multiple-locus variable-number tandem repeat analysis of Salmonella Enteritidis isolates from human and non-human sources using a single multiplex PCR. Fems Microbiology Letters. 275: 16-23. PMID 17692097 DOI: 10.1111/J.1574-6968.2007.00875.X  0.369
2007 Walk ST, Alm EW, Calhoun LM, Mladonicky JM, Whittam TS. Genetic diversity and population structure of Escherichia coli isolated from freshwater beaches. Environmental Microbiology. 9: 2274-88. PMID 17686024 DOI: 10.1111/J.1462-2920.2007.01341.X  0.72
2007 Bergholz TM, Tarr CL, Christensen LM, Betting DJ, Whittam TS. Recent gene conversions between duplicated glutamate decarboxylase genes (gadA and gadB) in pathogenic Escherichia coli. Molecular Biology and Evolution. 24: 2323-33. PMID 17675652 DOI: 10.1093/Molbev/Msm163  0.77
2007 Manning SD, Madera RT, Schneider W, Dietrich SE, Khalife W, Brown W, Whittam TS, Somsel P, Rudrik JT. Surveillance for Shiga toxin-producing Escherichia coli, Michigan, 2001-2005. Emerging Infectious Diseases. 13: 318-21. PMID 17479902 DOI: 10.3201/Eid1302.060813  0.444
2007 Bergholz TM, Whittam TS. Variation in acid resistance among enterohaemorrhagic Escherichia coli in a simulated gastric environment. Journal of Applied Microbiology. 102: 352-62. PMID 17241340 DOI: 10.1111/J.1365-2672.2006.03099.X  0.769
2007 Besser TE, Shaikh N, Holt NJ, Tarr PI, Konkel ME, Malik-Kale P, Walsh CW, Whittam TS, Bono JL. Greater diversity of Shiga toxin-encoding bacteriophage insertion sites among Escherichia coli O157:H7 isolates from cattle than in those from humans. Applied and Environmental Microbiology. 73: 671-9. PMID 17142358 DOI: 10.1128/Aem.01035-06  0.52
2007 Lacher DW, Steinsland H, Blank TE, Donnenberg MS, Whittam TS. Molecular evolution of typical enteropathogenic Escherichia coli: clonal analysis by multilocus sequence typing and virulence gene allelic profiling. Journal of Bacteriology. 189: 342-50. PMID 17098897 DOI: 10.1128/Jb.01472-06  0.784
2007 Alland D, Lacher DW, Hazbón MH, Motiwala AS, Qi W, Fleischmann RD, Whittam TS. Role of large sequence polymorphisms (LSPs) in generating genomic diversity among clinical isolates of Mycobacterium tuberculosis and the utility of LSPs in phylogenetic analysis. Journal of Clinical Microbiology. 45: 39-46. PMID 17079498 DOI: 10.1128/Jcm.02483-05  0.766
2006 Lacher DW, Steinsland H, Whittam TS. Allelic subtyping of the intimin locus (eae) of pathogenic Escherichia coli by fluorescent RFLP. Fems Microbiology Letters. 261: 80-7. PMID 16842363 DOI: 10.1111/J.1574-6968.2006.00328.X  0.722
2006 Saeed AM, Walk ST, Arshad M, Whittam TS. Clonal structure and variation in virulence of Salmonella enteritidis isolated from mice, chickens, and humans. Journal of Aoac International. 89: 504-11. PMID 16640300 DOI: 10.1093/Jaoac/89.2.504  0.687
2006 Zhang W, Qi W, Albert TJ, Motiwala AS, Alland D, Hyytia-Trees EK, Ribot EM, Fields PI, Whittam TS, Swaminathan B. Probing genomic diversity and evolution of Escherichia coli O157 by single nucleotide polymorphisms. Genome Research. 16: 757-67. PMID 16606700 DOI: 10.1101/Gr.4759706  0.738
2006 Monday SR, Keys C, Hanson P, Shen Y, Whittam TS, Feng P. Produce isolates of the Escherichia coli Ont:H52 serotype that carry both Shiga toxin 1 and stable toxin genes. Applied and Environmental Microbiology. 72: 3062-5. PMID 16598020 DOI: 10.1128/Aem.72.4.3062-3065.2006  0.563
2006 Palaniappan RU, Zhang Y, Chiu D, Torres A, Debroy C, Whittam TS, Chang YF. Differentiation of Escherichia coli pathotypes by oligonucleotide spotted array. Journal of Clinical Microbiology. 44: 1495-501. PMID 16597882 DOI: 10.1128/Jcm.44.4.1495-1501.2006  0.572
2006 Filliol I, Motiwala AS, Cavatore M, Qi W, Hazbón MH, Bobadilla del Valle M, Fyfe J, García-García L, Rastogi N, Sola C, Zozio T, Guerrero MI, León CI, Crabtree J, Angiuoli S, ... ... Whittam TS, et al. Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set. Journal of Bacteriology. 188: 759-72. PMID 16385065 DOI: 10.1128/Jb.188.2.759-772.2006  0.604
2005 Elena SF, Whittam TS, Winkworth CL, Riley MA, Lenski RE. Genomic divergence of Escherichia coli strains: evidence for horizontal transfer and variation in mutation rates. International Microbiology : the Official Journal of the Spanish Society For Microbiology. 8: 271-8. PMID 16562379  0.47
2005 Manning SD, Lacher DW, Davies HD, Foxman B, Whittam TS. DNA polymorphism and molecular subtyping of the capsular gene cluster of group B streptococcus. Journal of Clinical Microbiology. 43: 6113-6. PMID 16333106 DOI: 10.1128/Jcm.43.12.6113-6116.2005  0.676
2005 Fitch BR, Sachen KL, Wilder SR, Burg MA, Lacher DW, Khalife WT, Whittam TS, Young VB. Genetic diversity of Campylobacter sp. isolates from retail chicken products and humans with gastroenteritis in Central Michigan. Journal of Clinical Microbiology. 43: 4221-4. PMID 16081984 DOI: 10.1128/Jcm.43.8.4221-4224.2005  0.689
2005 Large TM, Walk ST, Whittam TS. Variation in acid resistance among shiga toxin-producing clones of pathogenic Escherichia coli. Applied and Environmental Microbiology. 71: 2493-500. PMID 15870339 DOI: 10.1128/Aem.71.5.2493-2500.2005  0.732
2005 Wick LM, Qi W, Lacher DW, Whittam TS. Evolution of genomic content in the stepwise emergence of Escherichia coli O157:H7. Journal of Bacteriology. 187: 1783-91. PMID 15716450 DOI: 10.1128/Jb.187.5.1783-1791.2005  0.819
2005 Hyma KE, Lacher DW, Nelson AM, Bumbaugh AC, Janda JM, Strockbine NA, Young VB, Whittam TS. Evolutionary genetics of a new pathogenic Escherichia species: Escherichia albertii and related Shigella boydii strains. Journal of Bacteriology. 187: 619-28. PMID 15629933 DOI: 10.1128/Jb.187.2.619-628.2005  0.826
2004 Anantha RP, McVeigh AL, Lee LH, Agnew MK, Cassels FJ, Scott DA, Whittam TS, Savarino SJ. Evolutionary and functional relationships of colonization factor antigen i and other class 5 adhesive fimbriae of enterotoxigenic Escherichia coli. Infection and Immunity. 72: 7190-201. PMID 15557644 DOI: 10.1128/Iai.72.12.7190-7201.2004  0.37
2004 He SY, Nomura K, Whittam TS. Type III protein secretion mechanism in mammalian and plant pathogens. Biochimica Et Biophysica Acta. 1694: 181-206. PMID 15546666 DOI: 10.1016/J.Bbamcr.2004.03.011  0.3
2004 Davies HD, Jones N, Whittam TS, Elsayed S, Bisharat N, Baker CJ. Multilocus sequence typing of serotype III group B streptococcus and correlation with pathogenic potential. The Journal of Infectious Diseases. 189: 1097-102. PMID 14999614 DOI: 10.1086/382087  0.428
2004 Qi W, Lacher DW, Bumbaugh AC, Hyma KE, Ouellette LM, Large TM, Tarr CL, Whittam TS. EcMLST: An online database for multi locus sequence typing of pathogenic escherichia coli Proceedings - 2004 Ieee Computational Systems Bioinformatics Conference, Csb 2004. 520-521.  0.791
2003 Schlager TA, Whittam TS, Hendley JO, Bhang JL, Wobbe CL, Stapleton A. Variation in frequency of the virulence-factor gene in Escherichia coli clones colonizing the stools and urinary tracts of healthy prepubertal girls. The Journal of Infectious Diseases. 188: 1059-64. PMID 14513428 DOI: 10.1086/377643  0.449
2003 Alland D, Whittam TS, Murray MB, Cave MD, Hazbon MH, Dix K, Kokoris M, Duesterhoeft A, Eisen JA, Fraser CM, Fleischmann RD. Modeling bacterial evolution with comparative-genome-based marker systems: application to Mycobacterium tuberculosis evolution and pathogenesis. Journal of Bacteriology. 185: 3392-9. PMID 12754238 DOI: 10.1128/Jb.185.11.3392-3399.2003  0.47
2003 Blank TE, Lacher DW, Scaletsky IC, Zhong H, Whittam TS, Donnenberg MS. Enteropathogenic Escherichia coli O157 strains from Brazil. Emerging Infectious Diseases. 9: 113-5. PMID 12533292 DOI: 10.3201/Eid0901.020072  0.768
2002 Maidhof H, Guerra B, Abbas S, Elsheikha HM, Whittam TS, Beutin L. A multiresistant clone of Shiga toxin-producing Escherichia coli O118:[H16] is spread in cattle and humans over different European countries. Applied and Environmental Microbiology. 68: 5834-42. PMID 12450802 DOI: 10.1128/Aem.68.12.5834-5842.2002  0.564
2002 Tarr CL, Large TM, Moeller CL, Lacher DW, Tarr PI, Acheson DW, Whittam TS. Molecular characterization of a serotype O121:H19 clone, a distinct Shiga toxin-producing clone of pathogenic Escherichia coli. Infection and Immunity. 70: 6853-9. PMID 12438362 DOI: 10.1128/Iai.70.12.6853-6859.2002  0.799
2002 Whittam TS, Bumbaugh AC. Inferences from whole-genome sequences of bacterial pathogens. Current Opinion in Genetics & Development. 12: 719-25. PMID 12433587 DOI: 10.1016/S0959-437X(02)00361-1  0.818
2002 Bumbaugh AC, McGraw EA, Page KL, Selander RK, Whittam TS. Sequence polymorphism of dotA and mip alleles mediating invasion and intracellular replication of Legionella pneumophila. Current Microbiology. 44: 314-22. PMID 11927981 DOI: 10.1007/S00284-01-0024-6  0.798
2002 Tarr CL, Whittam TS. Molecular evolution of the intimin gene in O111 clones of pathogenic Escherichia coli. Journal of Bacteriology. 184: 479-87. PMID 11751825 DOI: 10.1128/Jb.184.2.479-487.2002  0.584
2002 Davies RL, Campbell S, Whittam TS. Mosaic structure and molecular evolution of the leukotoxin operon (lktCABD) in Mannheimia (Pasteurella) haemolytica, Mannheimia glucosida, and Pasteurella trehalosi. Journal of Bacteriology. 184: 266-77. PMID 11741868 DOI: 10.1128/Jb.184.1.266-277.2002  0.46
2001 Monday SR, Whittam TS, Feng PC. Genetic and evolutionary analysis of mutations in the gusA gene that cause the absence of beta-glucuronidase activity in Escherichia coli O157:H7. The Journal of Infectious Diseases. 184: 918-21. PMID 11510000 DOI: 10.1086/323154  0.524
2001 May BJ, Zhang Q, Li LL, Paustian ML, Whittam TS, Kapur V. Complete genomic sequence of Pasteurella multocida, Pm70. Proceedings of the National Academy of Sciences of the United States of America. 98: 3460-5. PMID 11248100 DOI: 10.1073/Pnas.051634598  0.391
2001 Donnenberg MS, Whittam TS. Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli. The Journal of Clinical Investigation. 107: 539-48. PMID 11238553 DOI: 10.1172/Jci12404  0.515
2001 Davies RL, Whittam TS, Selander RK. Sequence diversity and molecular evolution of the leukotoxin (lktA) gene in bovine and ovine strains of Mannheimia (Pasteurella) haemolytica. Journal of Bacteriology. 183: 1394-404. PMID 11157953 DOI: 10.1128/JB.183.4.1394-1404.2001  0.418
2001 Johnson JR, Delavari P, Stell AL, Whittam TS, Carlino U, Russo TA. Erratum: Molecular comparison of extraintestinal Escherichia coli isolates of the same electrophoretic lineages from humans and domestic animals. (Journal of Infectious Diseases (January 1, 2001) 183 (154-159)) The Journal of Infectious Diseases. 183. DOI: 10.1086/317945  0.397
2000 Blank TE, Zhong H, Bell AL, Whittam TS, Donnenberg MS. Molecular variation among type IV pilin (bfpA) genes from diverse enteropathogenic Escherichia coli strains. Infection and Immunity. 68: 7028-38. PMID 11083828 DOI: 10.1128/Iai.68.12.7028-7038.2000  0.542
2000 Tarr PI, Schoening LM, Yea YL, Ward TR, Jelacic S, Whittam TS. Acquisition of the rfb-gnd cluster in evolution of Escherichia coli O55 and O157. Journal of Bacteriology. 182: 6183-91. PMID 11029441 DOI: 10.1128/JB.182.21.6183-6191.2000  0.438
2000 Herbelin CJ, Chirillo SC, Melnick KA, Whittam TS. Gene conservation and loss in the mutS-rpoS genomic region of pathogenic Escherichia coli. Journal of Bacteriology. 182: 5381-90. PMID 10986240 DOI: 10.1128/JB.182.19.5381-5390.2000  0.493
2000 Reid SD, Herbelin CJ, Bumbaugh AC, Selander RK, Whittam TS. Parallel evolution of virulence in pathogenic Escherichia coli. Nature. 406: 64-7. PMID 10894541 DOI: 10.1038/35017546  0.833
2000 Schlager TA, Whittam TS, Hendley JO, Wilson RA, Bhang J, Grady R, Stapleton A. Expression of virulence factors among Escherichia coli isolated from the periurethra and urine of children with neurogenic bladder on intermittent catheterization. The Pediatric Infectious Disease Journal. 19: 37-41. PMID 10643848  0.302
1999 Reid SD, Betting DJ, Whittam TS. Molecular detection and identification of intimin alleles in pathogenic Escherichia coli by multiplex PCR. Journal of Clinical Microbiology. 37: 2719-22. PMID 10405431 DOI: 10.1128/Jcm.37.8.2719-2722.1999  0.661
1999 Czeczulin JR, Whittam TS, Henderson IR, Navarro-Garcia F, Nataro JP. Phylogenetic analysis of enteroaggregative and diffusely adherent Escherichia coli. Infection and Immunity. 67: 2692-9. PMID 10338471 DOI: 10.1128/Iai.67.6.2692-2699.1999  0.435
1999 McGraw EA, Li J, Selander RK, Whittam TS. Molecular evolution and mosaic structure of alpha, beta, and gamma intimins of pathogenic Escherichia coli. Molecular Biology and Evolution. 16: 12-22. PMID 10331248 DOI: 10.1093/Oxfordjournals.Molbev.A026032  0.751
1999 Nagy B, Wilson RA, Whittam TS. Genetic diversity among Escherichia coli isolates carrying f18 genes from pigs with porcine postweaning diarrhea and edema disease. Journal of Clinical Microbiology. 37: 1642-5. PMID 10203547  0.396
1999 Schlager TA, Hendley JO, Wilson RA, Simon V, Whittam TS. Correlation of periurethral bacterial flora with bacteriuria and urinary tract infection in children with neurogenic bladder receiving intermittent catheterization. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 28: 346-50. PMID 10064254 DOI: 10.1086/515134  0.407
1999 Reid SD, Selander RK, Whittam TS. Sequence diversity of flagellin (fliC) alleles in pathogenic Escherichia coli. Journal of Bacteriology. 181: 153-60. PMID 9864325 DOI: 10.1128/Jb.181.1.153-160.1999  0.702
1998 Whittam TS, Reid SD, Selander RK. Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7. Emerging Infectious Diseases. 4: 615-7. PMID 9866737 DOI: 10.3201/Eid0404.980411  0.651
1998 Tarr PI, Clausen CR, Whittam TS, Wilson RA. Antibiotic resistance and O antigen expression in Escherichia coli. The Journal of Infectious Diseases. 177: 1774-5. PMID 9607874  0.305
1998 Feng P, Lampel KA, Karch H, Whittam TS. Genotypic and phenotypic changes in the emergence of Escherichia coli O157:H7. The Journal of Infectious Diseases. 177: 1750-3. PMID 9607864  0.412
1998 Whittam TS, McGraw EA, Reid SD. 5 Pathogenic Escherichia coli O157:H7: A model for emerging infectious diseases Biomedical Research Reports. 1: 163-183. DOI: 10.1016/S1874-5326(07)80029-9  0.814
1997 Wieler LH, McDaniel TK, Whittam TS, Kaper JB. Insertion site of the locus of enterocyte effacement in enteropathogenic and enterohemorrhagic Escherichia coli differs in relation to the clonal phylogeny of the strains. Fems Microbiology Letters. 156: 49-53. PMID 9368360 DOI: 10.1016/S0378-1097(97)00403-5  0.4
1997 Wang FS, Whittam TS, Selander RK. Evolutionary genetics of the isocitrate dehydrogenase gene (icd) in Escherichia coli and Salmonella enterica. Journal of Bacteriology. 179: 6551-9. PMID 9352899  0.503
1997 Sreevatsan S, Pan X, Stockbauer KE, Connell ND, Kreiswirth BN, Whittam TS, Musser JM. Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proceedings of the National Academy of Sciences of the United States of America. 94: 9869-74. PMID 9275218 DOI: 10.1073/Pnas.94.18.9869  0.317
1997 Bokete TN, Whittam TS, Wilson RA, Clausen CR, O'Callahan CM, Moseley SL, Fritsche TR, Tarr PI. Genetic and phenotypic analysis of Escherichia coli with enteropathogenic characteristics isolated from Seattle children. The Journal of Infectious Diseases. 175: 1382-9. PMID 9180177 DOI: 10.1086/516470  0.423
1997 Beutin L, Geier D, Zimmermann S, Aleksic S, Gillespie HA, Whittam TS. Epidemiological relatedness and clonal types of natural populations of Escherichia coli strains producing Shiga toxins in separate populations of cattle and sheep. Applied and Environmental Microbiology. 63: 2175-80. PMID 9172336  0.446
1997 Gonçalves AG, Campos LC, Gomes TA, Rodrigues J, Sperandio V, Whittam TS, Trabulsi LR. Virulence properties and clonal structures of strains of Escherichia coli O119 serotypes. Infection and Immunity. 65: 2034-40. PMID 9169729  0.448
1996 Boyd EF, Wang FS, Whittam TS, Selander RK. Molecular genetic relationships of the salmonellae. Applied and Environmental Microbiology. 62: 804-8. PMID 8975610  0.365
1996 Feng P, Fields PI, Swaminathan B, Whittam TS. Characterization of nonmotile variants of Escherichia coli O157 and other serotypes by using an antiflagellin monoclonal antibody. Journal of Clinical Microbiology. 34: 2856-9. PMID 8897201 DOI: 10.1128/Jcm.34.11.2856-2859.1996  0.415
1996 Ngeleka M, Kwaga JK, White DG, Whittam TS, Riddell C, Goodhope R, Potter AA, Allan B. Escherichia coli cellulitis in broiler chickens: clonal relationships among strains and analysis of virulence-associated factors of isolates from diseased birds. Infection and Immunity. 64: 3118-26. PMID 8757842 DOI: 10.1128/Iai.64.8.3118-3126.1996  0.413
1996 Rodrigues J, Scaletsky IC, Campos LC, Gomes TA, Whittam TS, Trabulsi LR. Clonal structure and virulence factors in strains of Escherichia coli of the classic serogroup O55. Infection and Immunity. 64: 2680-6. PMID 8698495  0.432
1996 Trabulsi LR, Campos LC, Whittam TS, Gomes TAT, Rodrigues J, Gonçalves AG. Traditional and non-traditional enteropathogenic Escherichia coli serogroups Revista De Microbiologia. 27: 1-6.  0.328
1996 Whittam TS, McGraw EA. Clonal analysis of EPEC serogroups Revista De Microbiologia. 27: 7-16.  0.586
1995 Maslow JN, Whittam TS, Gilks CF, Wilson RA, Mulligan ME, Adams KS, Arbeit RD. Clonal relationships among bloodstream isolates of Escherichia coli. Infection and Immunity. 63: 2409-17. PMID 7790051  0.411
1995 Kapur V, Sischo WM, Greer RS, Whittam TS, Musser JM. Molecular population genetic analysis of Staphylococcus aureus recovered from cows. Journal of Clinical Microbiology. 33: 376-80. PMID 7714195 DOI: 10.1128/Jcm.33.2.376-380.1995  0.302
1995 Schlager TA, Whittam TS, Hendley JO, Hollis RJ, Pfaller MA, Wilson RA, Stapleton A. Comparison of expression of virulence factors by Escherichia coli causing cystitis and E. coli colonizing the periurethra of healthy girls. The Journal of Infectious Diseases. 172: 772-7. PMID 7658071 DOI: 10.1093/Infdis/172.3.772  0.441
1995 Eardly BD, Wang FS, Whittam TS, Selander RK. Species limits in Rhizobium populations that nodulate the common bean (Phaseolus vulgaris). Applied and Environmental Microbiology. 61: 507-12. PMID 7574588  0.339
1995 Kapur V, Kanjilal S, Hamrick MR, Li LL, Whittam TS, Sawyer SA, Musser JM. Molecular population genetic analysis of the streptokinase gene of Streptococcus pyogenes: mosaic alleles generated by recombination. Molecular Microbiology. 16: 509-19. PMID 7565111 DOI: 10.1111/J.1365-2958.1995.Tb02415.X  0.315
1994 Samadpour M, Ongerth JE, Liston J, Tran N, Nguyen D, Whittam TS, Wilson RA, Tarr PI. Occurrence of Shiga-like toxin-producing Escherichia coli in retail fresh seafood, beef, lamb, pork, and poultry from grocery stores in Seattle, Washington. Applied and Environmental Microbiology. 60: 1038-40. PMID 8161171 DOI: 10.1128/Aem.60.3.1038-1040.1994  0.338
1994 Li J, Nelson K, McWhorter AC, Whittam TS, Selander RK. Recombinational basis of serovar diversity in Salmonella enterica. Proceedings of the National Academy of Sciences of the United States of America. 91: 2552-6. PMID 8146152  0.36
1994 Boyd EF, Nelson K, Wang FS, Whittam TS, Selander RK. Molecular genetic basis of allelic polymorphism in malate dehydrogenase (mdh) in natural populations of Escherichia coli and Salmonella enterica. Proceedings of the National Academy of Sciences of the United States of America. 91: 1280-4. PMID 8108402  0.4
1994 Campos LC, Whittam TS, Gomes TA, Andrade JR, Trabulsi LR. Escherichia coli serogroup O111 includes several clones of diarrheagenic strains with different virulence properties. Infection and Immunity. 62: 3282-8. PMID 8039899  0.488
1993 White DG, Wilson RA, Emery DA, Nagaraja KV, Whittam TS. Clonal diversity among strains of Escherichia coli incriminated in turkey colisepticemia. Veterinary Microbiology. 34: 19-34. PMID 8447077 DOI: 10.1016/0378-1135(93)90004-Q  0.374
1993 Li J, Smith NH, Nelson K, Crichton PB, Old DC, Whittam TS, Selander RK. Evolutionary origin and radiation of the avian-adapted non-motile salmonellae. Journal of Medical Microbiology. 38: 129-39. PMID 8429538  0.33
1993 White DG, Dho-Moulin M, Wilson RA, Whittam TS. Clonal relationships and variation in virulence among Escherichia coli strains of avian origin. Microbial Pathogenesis. 14: 399-409. PMID 8366817 DOI: 10.1006/mpat.1993.1039  0.459
1993 Wang G, Whittam TS, Berg CM, Berg DE. RAPD (arbitrary primer) PCR is more sensitive than multilocus enzyme electrophoresis for distinguishing related bacterial strains. Nucleic Acids Research. 21: 5930-3. PMID 8290354 DOI: 10.1093/Nar/21.25.5930  0.483
1993 Whittam TS, Wolfe ML, Wachsmuth IK, Orskov F, Orskov I, Wilson RA. Clonal relationships among Escherichia coli strains that cause hemorrhagic colitis and infantile diarrhea. Infection and Immunity. 61: 1619-29. PMID 7682992  0.475
1992 Kapur V, White DG, Wilson RA, Whittam TS. Outer membrane protein patterns mark clones of Escherichia coli O2 and O78 strains that cause avian septicemia. Infection and Immunity. 60: 1687-91. PMID 1372298 DOI: 10.1128/Iai.60.4.1687-1691.1992  0.488
1991 Beltran P, Plock SA, Smith NH, Whittam TS, Old DC, Selander RK. Reference collection of strains of the Salmonella typhimurium complex from natural populations. Journal of General Microbiology. 137: 601-6. PMID 2033380  0.304
1991 Nelson K, Whittam TS, Selander RK. Nucleotide polymorphism and evolution in the glyceraldehyde-3-phosphate dehydrogenase gene (gapA) in natural populations of Salmonella and Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 88: 6667-71. PMID 1862091 DOI: 10.1073/pnas.88.15.6667  0.45
1990 Selander RK, Beltran P, Smith NH, Barker RM, Crichton PB, Old DC, Musser JM, Whittam TS. Genetic population structure, clonal phylogeny, and pathogenicity of Salmonella paratyphi B. Infection and Immunity. 58: 1891-901. PMID 2341183  0.32
1990 White DG, Wilson RA, Gabriel AS, Saco M, Whittam TS. Genetic relationships among strains of avian Escherichia coli associated with swollen-head syndrome. Infection and Immunity. 58: 3613-20. PMID 2228231 DOI: 10.1128/Iai.58.11.3613-3620.1990  0.511
1990 Orskov F, Whittam TS, Cravioto A, Orskov I. Clonal relationships among classic enteropathogenic Escherichia coli (EPEC) belong to different O groups. The Journal of Infectious Diseases. 162: 76-81. PMID 2192012  0.357
1990 Beutin L, Orskov I, Orskov F, Zimmermann S, Prada J, Gelderblom H, Stephan R, Whittam TS. Clonal diversity and virulence factors in strains of Escherichia coli of the classic enteropathogenic serogroup O114. The Journal of Infectious Diseases. 162: 1329-34. PMID 1977809  0.46
1990 Herzer PJ, Inouye S, Inouye M, Whittam TS. Phylogenetic distribution of branched RNA-linked multicopy single-stranded DNA among natural isolates of Escherichia coli. Journal of Bacteriology. 172: 6175-81. PMID 1699928 DOI: 10.1128/Jb.172.11.6175-6181.1990  0.426
1988 Whittam TS, Wachsmuth IK, Wilson RA. Genetic evidence of clonal descent of Escherichia coli O157:H7 associated with hemorrhagic colitis and hemolytic uremic syndrome Journal of Infectious Diseases. 157: 1124-1133. PMID 3286782  0.337
1988 Whittam TS, Wilson RA. Genetic relationships among pathogenic strains of avian Escherichia coli Infection and Immunity. 56: 2458-2466. PMID 3045001  0.394
1988 Whittam TS, Wilson RA. Genetic relationships among pathogenic Escherichia coli of serogroup O157 Infection and Immunity. 56: 2467-2473. PMID 2457555  0.378
1987 Caugant DA, Zollinger WD, Mocca LF, Frasch CE, Whittam TS, Frøholm LO, Selander RK. Genetic relationships and clonal population structure of serotype 2 strains of Neisseria meningitidis. Infection and Immunity. 55: 1503-12. PMID 3106223  0.316
1983 Ochman H, Whittam TS, Caugant DA, Selander RK. Enzyme polymorphism and genetic population structure in Escherichia coli and Shigella Journal of General Microbiology. 129: 2715-2726. PMID 6355392 DOI: 10.1099/00221287-129-9-2715  0.403
1983 Whittam TS, Ochman H, Selander RK. Multilocus genetic structure in natural populations of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 80: 1751-1755. PMID 6340107 DOI: 10.1073/Pnas.80.6.1751  0.315
1983 Caugant DA, Levin BR, Lidin-Janson G, Whittam TS, Svanborg Edén C, Selander RK. Genetic diversity and relationships among strains of Escherichia coli in the intestine and those causing urinary tract infections. Progress in Allergy. 33: 203-27. PMID 6338512 DOI: 10.1159/000318331  0.318
1980 Whittam TS, Rosenzweig ML. Introduction to Population Biology & Evolution.Otto T. Solbrig , Dorothy J. Solbrig The Quarterly Review of Biology. 55: 178-178. DOI: 10.1086/411755  0.452
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