Asger Hobolth, Ph.D. - Publications

Affiliations: 
Aarhus University, Aarhus, Denmark 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hobolth A, Siri-Jégousse A, Bladt M. Phase-type distributions in population genetics. Theoretical Population Biology. PMID 30822431 DOI: 10.1016/J.Tpb.2019.02.001  0.37
2019 Speed MS, Balding DJ, Hobolth A. A general framework for moment-based analysis of genetic data. Journal of Mathematical Biology. PMID 30734077 DOI: 10.1007/S00285-018-01325-0  0.369
2018 Nielsen MM, Tataru P, Madsen T, Hobolth A, Pedersen JS. Regmex: a statistical tool for exploring motifs in ranked sequence lists from genomics experiments. Algorithms For Molecular Biology : Amb. 13: 17. PMID 30555524 DOI: 10.1186/S13015-018-0135-2  0.338
2018 Skov L, Hui R, Shchur V, Hobolth A, Scally A, Schierup MH, Durbin R. Detecting archaic introgression using an unadmixed outgroup. Plos Genetics. 14: e1007641. PMID 30226838 DOI: 10.1371/Journal.Pgen.1007641  0.369
2018 Juul M, Madsen T, Guo Q, Bertl J, Hobolth A, Kellis M, Pedersen JS. ncdDetect2: Improved models of the site-specific mutation rate in cancer and driver detection with robust significance evaluation. Bioinformatics (Oxford, England). PMID 29945188 DOI: 10.1093/Bioinformatics/Bty511  0.338
2018 Waltoft BL, Hobolth A. Non-parametric estimation of population size changes from the site frequency spectrum. Statistical Applications in Genetics and Molecular Biology. PMID 29886455 DOI: 10.1515/Sagmb-2017-0061  0.343
2018 Bertl J, Guo Q, Juul M, Besenbacher S, Nielsen MM, Hornshøj H, Pedersen JS, Hobolth A. A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data. Bmc Bioinformatics. 19: 147. PMID 29673314 DOI: 10.1186/S12859-018-2141-2  0.354
2018 Hornshøj H, Nielsen MM, Sinnott-Armstrong NA, Świtnicki MP, Juul M, Madsen T, Sallari R, Kellis M, Ørntoft T, Hobolth A, Pedersen JS. Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival. Npj Genomic Medicine. 3: 1. PMID 29354286 DOI: 10.1038/S41525-017-0040-5  0.31
2017 Juul M, Bertl J, Guo Q, Nielsen MM, Świtnicki M, Hornshøj H, Madsen T, Hobolth A, Pedersen JS. Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate. Elife. 6. PMID 28362259 DOI: 10.7554/Elife.21778  0.337
2017 Madsen T, Hobolth A, Jensen JL, Pedersen JS. Significance evaluation in factor graphs. Bmc Bioinformatics. 18: 199. PMID 28359297 DOI: 10.1186/S12859-017-1614-Z  0.315
2017 Tataru P, Simonsen M, Bataillon T, Hobolth A. Statistical Inference in the Wright-Fisher Model Using Allele Frequency Data. Systematic Biology. 66: e30-e46. PMID 28173553 DOI: 10.1093/Sysbio/Syw056  0.376
2017 Juul M, Bertl J, Guo Q, Nielsen MM, Świtnicki M, Hornshøj H, Madsen T, Hobolth A, Pedersen JS. Author response: Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate Elife. DOI: 10.7554/Elife.21778.052  0.321
2016 Schrempf D, Hobolth A. An alternative derivation of the stationary distribution of the multivariate neutral Wright-Fisher model for low mutation rates with a view to mutation rate estimation from site frequency data. Theoretical Population Biology. PMID 28041892 DOI: 10.1016/J.Tpb.2016.12.001  0.354
2015 Hobolth A, Siren J. The multivariate Wright-Fisher process with mutation: Moment-based analysis and inference using a hierarchical Beta model. Theoretical Population Biology. PMID 26612605 DOI: 10.1016/J.Tpb.2015.11.001  0.37
2015 Tataru P, Bataillon T, Hobolth A. Inference Under a Wright-Fisher Model Using an Accurate Beta Approximation. Genetics. 201: 1133-41. PMID 26311474 DOI: 10.1534/Genetics.115.179606  0.348
2015 Bataillon T, Duan J, Hvilsom C, Jin X, Li Y, Skov L, Glemin S, Munch K, Jiang T, Qian Y, Hobolth A, Wang J, Mailund T, Siegismund HR, Schierup MH. Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing. Genome Biology and Evolution. 7: 1122-32. PMID 25829516 DOI: 10.1093/Gbe/Evv058  0.357
2015 Wilton PR, Carmi S, Hobolth A. The SMC' Is a Highly Accurate Approximation to the Ancestral Recombination Graph. Genetics. 200: 343-55. PMID 25786855 DOI: 10.1534/Genetics.114.173898  0.366
2014 Hobolth A, Jensen JL. Markovian approximation to the finite loci coalescent with recombination along multiple sequences. Theoretical Population Biology. 98: 48-58. PMID 24486389 DOI: 10.1016/J.Tpb.2014.01.002  0.348
2014 Andersen LN, Mailund T, Hobolth A. Efficient computation in the IM model. Journal of Mathematical Biology. 68: 1423-51. PMID 23588350 DOI: 10.1007/S00285-013-0671-9  0.396
2013 Tataru P, Sand A, Hobolth A, Mailund T, Pedersen CN. Algorithms for hidden markov models restricted to occurrences of regular expressions. Biology. 2: 1282-95. PMID 24833225 DOI: 10.3390/Biology2041282  0.357
2013 Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, ... Hobolth A, et al. Great ape genetic diversity and population history. Nature. 499: 471-5. PMID 23823723 DOI: 10.1038/Nature12228  0.339
2012 Mailund T, Halager AE, Westergaard M, Dutheil JY, Munch K, Andersen LN, Lunter G, Prüfer K, Scally A, Hobolth A, Schierup MH. A new isolation with migration model along complete genomes infers very different divergence processes among closely related great ape species. Plos Genetics. 8: e1003125. PMID 23284294 DOI: 10.1371/Journal.Pgen.1003125  0.438
2012 Prüfer K, Munch K, Hellmann I, Akagi K, Miller JR, Walenz B, Koren S, Sutton G, Kodira C, Winer R, Knight JR, Mullikin JC, Meader SJ, Ponting CP, Lunter G, ... ... Hobolth A, et al. The bonobo genome compared with the chimpanzee and human genomes. Nature. 486: 527-31. PMID 22722832 DOI: 10.1038/Nature11128  0.326
2012 Dutheil JY, Hobolth A. Ancestral population genomics. Methods in Molecular Biology (Clifton, N.J.). 856: 293-313. PMID 22399464 DOI: 10.1007/978-1-61779-585-5_12  0.38
2012 Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, et al. Insights into hominid evolution from the gorilla genome sequence. Nature. 483: 169-75. PMID 22398555 DOI: 10.1038/Nature10842  0.395
2012 Hvilsom C, Qian Y, Bataillon T, Li Y, Mailund T, Sallé B, Carlsen F, Li R, Zheng H, Jiang T, Jiang H, Jin X, Munch K, Hobolth A, Siegismund HR, et al. Extensive X-linked adaptive evolution in central chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 109: 2054-9. PMID 22308321 DOI: 10.1073/Pnas.1106877109  0.316
2011 Tataru P, Hobolth A. Comparison of methods for calculating conditional expectations of sufficient statistics for continuous time Markov chains. Bmc Bioinformatics. 12: 465. PMID 22142146 DOI: 10.1186/1471-2105-12-465  0.349
2011 Mailund T, Dutheil JY, Hobolth A, Lunter G, Schierup MH. Estimating divergence time and ancestral effective population size of Bornean and Sumatran orangutan subspecies using a coalescent hidden Markov model. Plos Genetics. 7: e1001319. PMID 21408205 DOI: 10.1371/Journal.Pgen.1001319  0.409
2011 Hobolth A, Andersen LN, Mailund T. On computing the coalescence time density in an isolation-with-migration model with few samples. Genetics. 187: 1241-3. PMID 21321131 DOI: 10.1534/Genetics.110.124164  0.336
2011 Locke DP, Hillier LW, Warren WC, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla AT, Minx P, Mitreva M, Cook L, Delehaunty KD, Fronick C, Schmidt H, ... ... Hobolth A, et al. Comparative and demographic analysis of orang-utan genomes. Nature. 469: 529-33. PMID 21270892 DOI: 10.1038/Nature09687  0.377
2011 Hobolth A, Dutheil JY, Hawks J, Schierup MH, Mailund T. Incomplete lineage sorting patterns among human, chimpanzee, and orangutan suggest recent orangutan speciation and widespread selection. Genome Research. 21: 349-56. PMID 21270173 DOI: 10.1101/Gr.114751.110  0.34
2011 Hobolth A, Jensen JL. Summary statistics for endpoint-conditioned continuous-time Markov chains Journal of Applied Probability. 48: 911-924. DOI: 10.1239/Jap/1324046009  0.323
2009 Hobolth A, Stone EA. SIMULATION FROM ENDPOINT-CONDITIONED, CONTINUOUS-TIME MARKOV CHAINS ON A FINITE STATE SPACE, WITH APPLICATIONS TO MOLECULAR EVOLUTION. The Annals of Applied Statistics. 3: 1204. PMID 20148133 DOI: 10.1214/09-Aoas247  0.323
2009 Dutheil JY, Ganapathy G, Hobolth A, Mailund T, Uyenoyama MK, Schierup MH. Ancestral population genomics: the coalescent hidden Markov model approach. Genetics. 183: 259-74. PMID 19581452 DOI: 10.1534/Genetics.109.103010  0.431
2008 Hobolth A, Uyenoyama MK, Wiuf C. Importance sampling for the infinite sites model. Statistical Applications in Genetics and Molecular Biology. 7: Article32. PMID 18976228 DOI: 10.2202/1544-6115.1400  0.326
2008 Hobolth A. A Markov Chain Monte Carlo expectation maximization algorithm for statistical analysis of DNA sequence evolution with neighbor-dependent substitution rates Journal of Computational and Graphical Statistics. 17: 138-162. DOI: 10.1198/106186008X289010  0.358
2007 Choi SC, Hobolth A, Robinson DM, Kishino H, Thorne JL. Quantifying the impact of protein tertiary structure on molecular evolution. Molecular Biology and Evolution. 24: 1769-82. PMID 17522088 DOI: 10.1093/Molbev/Msm097  0.63
2007 Hobolth A, Christensen OF, Mailund T, Schierup MH. Genomic relationships and speciation times of human, chimpanzee, and gorilla inferred from a coalescent hidden Markov model. Plos Genetics. 3: e7. PMID 17319744 DOI: 10.1371/Journal.Pgen.0030007  0.394
2006 Jónsdóttir KY, Hoffmann LM, Hobolth A, Vedel Jensen EB. On error prediction in circular systematic sampling. Journal of Microscopy. 222: 212-6. PMID 16872420 DOI: 10.1111/J.1365-2818.2006.01589.X  0.322
2005 Hobolth A, Jensen JL. Statistical inference in evolutionary models of DNA sequences via the EM algorithm. Statistical Applications in Genetics and Molecular Biology. 4: Article18. PMID 16646835 DOI: 10.2202/1544-6115.1127  0.334
2005 Christensen OF, Hobolth A, Jensen JL. Pseudo-likelihood analysis of codon substitution models with neighbor-dependent rates. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 1166-82. PMID 16305327 DOI: 10.1089/Cmb.2005.12.1166  0.407
2005 Hobolth A, Jensen JL. Applications of hidden Markov models for characterization of homologous DNA sequences with a common gene. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 12: 186-203. PMID 15767776 DOI: 10.1089/Cmb.2005.12.186  0.373
2005 Jørgensen FG, Hobolth A, Hornshøj H, Bendixen C, Fredholm M, Schierup MH. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Bmc Biology. 3: 2. PMID 15679890 DOI: 10.1186/1741-7007-3-2  0.41
2003 Hobolth A, Pedersen J, Jensen EBV. A continuous parametric shape model Annals of the Institute of Statistical Mathematics. 55: 227-242. DOI: 10.1007/Bf02530496  0.355
2002 Hobolth A, Jensen EBV. A note on design-based versus model-based variance estimation in stereology Advances in Applied Probability. 34: 484-490. DOI: 10.1239/Aap/1033662161  0.34
2002 Hobolth A, Pedersen J, Vedel Jensen EB. A deformable template model, with special reference to elliptical templates Journal of Mathematical Imaging and Vision. 17: 131-137. DOI: 10.1023/A:1020681419750  0.333
2000 Hobolth A, Jensen EBV. Modelling stochastic changes in curve shape, with an application to cancer diagnostics Advances in Applied Probability. 32: 344-362. DOI: 10.1239/Aap/1013540167  0.35
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