Peter McGuffin, PhD FRCP FRCPsych FMedSci

Affiliations: 
Social, Genetic and Developmental Psychiatry King's College London, London, UK 
Area:
psychiatric genetics
Website:
http://www.iop.kcl.ac.uk/staff/profile/default.aspx?go=10199
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"Peter McGuffin"
Bio:

Peter McGuffin was born in Belfast and emigrated with his parents at aged 10 to the Isle of Wight. He first decided that he wanted to be a psychiatrist at the age of 16 after coming across (something he’d never heard of before) Freud’s ‘Introductory Lectures on Psychoanalysis’, in a local public library. He attended medical school at the University of Leeds, England where he graduated in 1972 and then received postgraduate training in internal medicine. It was at this stage that he became interested in genetics and had his first publications on immunogenetic aspects of coronary heart disease. He transferred this interest to psychiatric disorders and (with his wife Anne Farmer, also now a professor at the IoP) carried out one of the first genetic marker association studies on schizophrenia.He completed his training as a psychiatrist at the Maudsley Hospital, London and was awarded a Medical Research Council Fellowship to study genetics at London University and at Washington University, St Louis Missouri.He subsequently became an MRC Senior Clinical Fellow at the Maudsley and the Institute of Psychiatry and then moved to Cardiff where he held the Chair of Psychological Medicine at the University of Wales College of Medicine from Jan 1987 to September 1998. He returned to The Institute of Psychiatry as Director of the MRC SGDP Centre in October 1998 and held this post until December 2006 and then served a 3 year term as Dean and Head of School from January 2007 to December 2009. He is married with 3 grown up children and his interests outside of work include horse riding,driving his tractor, playing the classical guitar and running with his dogs.
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Publications

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Munn-Chernoff MA, Johnson EC, Chou YL, et al. (2020) Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology. e12880
Glanville KP, Coleman JRI, Hanscombe KB, et al. (2019) Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biological Psychiatry
Madsen T, Buttenschøn HN, Uher R, et al. (2019) Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder. The Journal of Clinical Psychiatry. 80
Mullins N, Bigdeli TB, Børglum AD, et al. (2019) GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. The American Journal of Psychiatry. appiajp201918080957
Stahl EA, Breen G, Forstner AJ, et al. (2019) Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics
Zhang X, Abdellaoui A, Rucker J, et al. (2019) Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biological Psychiatry
Köhler-Forsberg O, Larsen ER, Buttenschøn HN, et al. (2019) Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder. The British Journal of Psychiatry : the Journal of Mental Science. 1-8
Talarico F, Uher R, Farmer A, et al. (2019) T75Gwas And Pathway Enrichment Analysis In Adverse Drug Reactions In Depression European Neuropsychopharmacology. 29
Ren H, Fabbri C, Uher R, et al. (2019) Genome-Wide Association Study Of Anhedonia In Gendep Using A Linear Mixed Model Identifies Candidates With Relevant Biological Function European Neuropsychopharmacology. 29
Fabbri C, Tansey KE, Perlis RH, et al. (2018) Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 28: 945-954
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