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Michael L. Stitzel, Ph.D. - Publications

Affiliations: 
2007 Johns Hopkins University, Baltimore, MD 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lawlor N, Kursawe R, Stitzel ML. 2061-P: Islet Single Cell Transcriptomes Reveal Cellular and Gene Regulatory Alterations in Type 2 Diabetes Pathogenesis Diabetes. 69. DOI: 10.2337/Db20-2061-P  0.364
2019 Lawlor N, Stitzel ML. (Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes. Molecular Metabolism. 27: S15-S24. PMID 31500827 DOI: 10.1016/J.Molmet.2019.06.002  0.358
2019 Lawlor N, Márquez EJ, Orchard P, Narisu N, Shamim MS, Thibodeau A, Varshney A, Kursawe R, Erdos MR, Kanke M, Gu H, Pak E, Dutra A, Russell S, Li X, ... ... Stitzel ML, et al. Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function. Cell Reports. 26: 788-801.e6. PMID 30650367 DOI: 10.1016/J.Celrep.2018.12.083  0.351
2018 Varshney A, VanRenterghem H, Orchard P, Boyle AP, Stitzel ML, Ucar D, Parker SCJ. Cell Specificity of Human Regulatory Annotations and Their Genetic Effects on Gene Expression. Genetics. PMID 30593493 DOI: 10.1534/Genetics.118.301525  0.38
2018 Khetan S, Kursawe R, Youn A, Lawlor N, Jillette A, Marquez EJ, Ucar D, Stitzel ML. Type 2 Diabetes Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets. Diabetes. PMID 30181159 DOI: 10.2337/Db18-0393  0.372
2018 Wu Z, Zhang Y, Stitzel ML, Wu H. Two-phase differential expression analysis for single cell RNA-seq. Bioinformatics (Oxford, England). PMID 29688282 DOI: 10.1093/Bioinformatics/Bty329  0.321
2017 Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Stitzel ML, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179  0.308
2017 Lawlor N, Youn A, Kursawe R, Ucar D, Stitzel ML. Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts. Scientific Reports. 7: 11959. PMID 28931935 DOI: 10.1038/S41598-017-12335-1  0.392
2017 Roman TS, Cannon ME, Vadlamudi S, Buchkovich ML, Wolford BN, Welch RP, Morken MA, Kwon GJ, Varshney A, Kursawe R, Wu Y, Jackson AU, Erdos MR, Kuusisto J, ... ... Stitzel ML, et al. A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the Adcy5 Locus. Diabetes. PMID 28684635 DOI: 10.2337/Db17-0464  0.387
2017 Lawlor N, Khetan S, Ucar D, Stitzel ML. Genomics of Islet (Dys)function and Type 2 Diabetes. Trends in Genetics : Tig. PMID 28245910 DOI: 10.1016/J.Tig.2017.01.010  0.372
2017 Varshney A, Scott LJ, Welch RP, Erdos MR, Chines PS, Narisu N, Albanus RD, Orchard P, Wolford BN, Kursawe R, Vadlamudi S, Cannon ME, Didion JP, Hensley J, Kirilusha A, ... ... Stitzel ML, et al. Genetic regulatory signatures underlying islet gene expression and type 2 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193859 DOI: 10.1073/Pnas.1621192114  0.38
2016 Lawlor N, George J, Bolisetty M, Kursawe R, Sun L, V S, Kycia I, Robson P, Stitzel ML. Single cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes. Genome Research. PMID 27864352 DOI: 10.1101/Gr.212720.116  0.388
2016 Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Stitzel ML, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642  0.332
2016 Zubek J, Stitzel ML, Ucar D, Plewczynski DM. Computational inference of H3K4me3 and H3K27ac domain length. Peerj. 4: e1750. PMID 26989607 DOI: 10.7717/Peerj.1750  0.344
2015 Stitzel ML, Kycia I, Kursawe R, Ucar D. Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function. Current Diabetes Reports. 15: 635. PMID 26272056 DOI: 10.1007/S11892-015-0635-0  0.368
2014 Kulzer JR, Stitzel ML, Morken MA, Huyghe JR, Fuchsberger C, Kuusisto J, Laakso M, Boehnke M, Collins FS, Mohlke KL. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell. American Journal of Human Genetics. 94: 186-97. PMID 24439111 DOI: 10.1016/J.Ajhg.2013.12.011  0.381
2014 Wang Y, Wang JT, Rasoloson D, Stitzel ML, O' Connell KF, Smith HE, Seydoux G. Identification of suppressors of mbk-2/DYRK by whole-genome sequencing. G3 (Bethesda, Md.). 4: 231-41. PMID 24347622 DOI: 10.1534/G3.113.009126  0.551
2013 Parker SC, Stitzel ML, Taylor DL, Orozco JM, Erdos MR, Akiyama JA, van Bueren KL, Chines PS, Narisu N, Black BL, Visel A, Pennacchio LA, Collins FS, et al. Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proceedings of the National Academy of Sciences of the United States of America. 110: 17921-6. PMID 24127591 DOI: 10.1073/Pnas.1317023110  0.405
2013 Bonnycastle LL, Chines PS, Hara T, Huyghe JR, Swift AJ, Heikinheimo P, Mahadevan J, Peltonen S, Huopio H, Nuutila P, Narisu N, Goldfeder RL, Stitzel ML, Lu S, Boehnke M, et al. Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation. Diabetes. 62: 3943-50. PMID 23903355 DOI: 10.2337/Db13-0571  0.313
2013 Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK, et al. Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 13481-6. PMID 23901115 DOI: 10.1073/Pnas.1304227110  0.318
2010 Stitzel ML, Sethupathy P, Pearson DS, Chines PS, Song L, Erdos MR, Welch R, Parker SC, Boyle AP, Scott LJ, Margulies EH, Boehnke M, Furey TS, Crawford GE, et al. Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metabolism. 12: 443-55. PMID 21035756 DOI: 10.1016/J.Cmet.2010.09.012  0.373
2010 Stitzel ML, Sethupathy P, Pearson DS, Chines PS, Song L, Erdos MR, Welch R, Parker SCJ, Boyle AP, Scott LJ, Program NCS, Margulies EH, Boehnke M, Furey TS, Crawford GE, et al. Erratum: Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci (Cell Metabolism (2010) 12 (443-455)) Cell Metabolism. 12. DOI: 10.1016/J.Cmet.2010.11.013  0.313
2007 Stitzel ML, Cheng KC, Seydoux G. Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition. Current Biology : Cb. 17: 1545-54. PMID 17869113 DOI: 10.1016/J.Cub.2007.08.049  0.644
2007 Stitzel ML, Seydoux G. Regulation of the oocyte-to-zygote transition. Science (New York, N.Y.). 316: 407-8. PMID 17446393 DOI: 10.1126/Science.1138236  0.63
2006 Stitzel ML, Pellettieri J, Seydoux G. The C. elegans DYRK Kinase MBK-2 Marks Oocyte Proteins for Degradation in Response to Meiotic Maturation. Current Biology : Cb. 16: 56-62. PMID 16338136 DOI: 10.1016/J.Cub.2005.11.063  0.587
2001 Stitzel ML, Durso R, Reese JC. The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4. Genes & Development. 15: 128-33. PMID 11157770 DOI: 10.1101/Gad.863801  0.398
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